PMID- 4134351 TI - Letter: Psychiatric services and the future. PMID- 4134352 TI - Letter: Isolation of the mentally handicapped. PMID- 4134353 TI - Letter: Selecting the sex of one's children. PMID- 4134354 TI - Letter: Carbon monoxide and smoking. PMID- 4134355 TI - Letter: Bowie and Dick test. PMID- 4134356 TI - Letter: Lymphoid malignancy. PMID- 4134357 TI - Letter: Diabetic retinopathy and prolactin. PMID- 4134358 TI - [Indications and uses of various pyelographic techniques (author's transl)]. PMID- 4134360 TI - Laryngectomy: paving the way to successful adjustment. Nursing grand rounds. PMID- 4134359 TI - [Progestagens in gynecologic oncology]. PMID- 4134361 TI - Herpes zoster as a cause of urinary retention. PMID- 4134362 TI - [Nursing of patients following intra-ocular operations]. PMID- 4134363 TI - Social service supports cardiac patients. PMID- 4134364 TI - [Tetracycline-distribution in kidney- and prostato-tissue of men suffering from kidney- and prostato-diseases (author's transl)]. PMID- 4134365 TI - Microfiche for self-study in ocular pathology. PMID- 4134366 TI - Examples of community prevention projects: Winners of ADA Preventive Dentistry Award. Council on Dental Health. PMID- 4134367 TI - Inhibition of migration of guinea pig macrophages and mouse spleen cells by unconcentrated human MIF in serum-free medium. PMID- 4134368 TI - Proceedings: Immunological determinants of luteinizing hormone and human chorionic gonadotrophin: contributions of the sub-units and of the conformation of the native hormone. PMID- 4134369 TI - Gramicidin S analogs containing N-methylleucine in place of leucine. PMID- 4134370 TI - Evaluation of T-cells and thymic serum factors in man using the rosette technique. PMID- 4134371 TI - A comparison of antigenic structure and phage pattern with biochemical properties of Staphylococcus aureus strains isolated from hares and mink. PMID- 4134372 TI - Identification of small amounts of antibiotics by electrophoresis and bio autography. PMID- 4134373 TI - Role of blocking serum factors in organ grafted rats. PMID- 4134374 TI - [Modern views on diagnostic technic in cases of serological conflicts]. PMID- 4134375 TI - Scleral plaques. I. Incidence and morphology. PMID- 4134376 TI - Malignant lymphoma of the eye and brain. Report of a case. PMID- 4134377 TI - Combined maternal erythrocyte autosensitization and materno-fetal Jk incompatibility. PMID- 4134378 TI - The risk of immunization IgG following Rh immune globulin therapy. PMID- 4134379 TI - Evidence for two anomalous I blood group determinants. PMID- 4134380 TI - Electron microscopy and immunoelectronmicroscopy of cytoplasmic hepatitis B antigen in hepatocytes. AB - The localization of hepatitis B antigen (HB Ag) and the nature of the virus-like particles in hepatocytes of patients with HB antigenemia are controversial. In many reports, numerous virus-like particles have been demonstrated in hepatocytic nuclei; the few reported in the cytoplasm are insufficient in number to explain the intense cytoplasmic fluorescence after staining with fluoresceinated antibody to HB Ag (HB Ab). We found numerous tubular and circular structures, measuring 20 to 30 nm in diameter, in the cisternae of the excess smooth endoplasmic reticulum (ER) of varying numbers of hepatocytes in 13 of 16 HB Ag carriers and in 4 of 9 patients with HB Ag-positive chronic hepatitis corresponding to cytoplasmic HB Ag specific fluorescence. Direct immunoelectronmicroscopy using peroxidase-labeled HB Ab revealed that the intracisternal bodies and the surrounding membranes contain HB antigenic determinants. These bodies are an ultrastructural correlate of cytoplasmic HB Ag. It is suggested that they are virally coded coat material rather than the mature hepatitis B virus or its core. PMID- 4134381 TI - [Tropochemical dyeing and staining reactions on solid polymer phases (author's transl)]. PMID- 4134382 TI - [Model experiment for quantitative photometry on tissue slices (author's transl)]. PMID- 4134383 TI - Detection of Aleutian disease in mink: serum-plate agglutination using iodine compared with precipitation by agar-gel electrophoresis. PMID- 4134384 TI - Sex hormones and kinetics of anphylactic histamine release. PMID- 4134385 TI - Giemsa banding patterns in the chromosomes of twelve species of cats (Felidae). PMID- 4134386 TI - Chromosomal banding patterns of two paracentric inversions in mice. PMID- 4134387 TI - Nonrandom distribution of chromosome breaks in Fanconi's anemia. PMID- 4134388 TI - Karyotype of the chimpanzee, Pan troglodytes, based on measurements and banding pattern: comparison to the human karyotype. PMID- 4134389 TI - [The electrocardiogram in idiopathic polyneuritis (author's transl)]. PMID- 4134390 TI - Convergent morphological evolution detected by studying proteins of tree frogs in the Hyla eximia species group. AB - Protein studies have uncovered an apparent case of convergent evolution among North American tree frogs. The species Hyla eximia and Hyla regilla are so similar in external morphology that the "wrightorum" subspecies is assigned by some authorities to H. eximia and by others to H. regilla. Yet microcomplement fixation experiments show that "wrightorum" albumin, though virtually indistinguishable from authentic H. eximia albumin, differs as much from H. regilla albumin as from albumins of species outside the genus Hyla, such as Acris crepitans. The morphological resemblance of "wrightorum" to H. regilla is thus probably due to convergence. PMID- 4134391 TI - A quantitative study of the peripheral nerve supply in the tadpole tail. PMID- 4134392 TI - [Indications for adenomectomy based on roentgenocinematocystography]. PMID- 4134393 TI - [Some indices of histamine metabolism in adolescents with chronic tonsillitis]. PMID- 4134394 TI - [Use of kenakort and kenacomb in the therapy of certain dermatoses]. PMID- 4134395 TI - Activation of a C-type virus from the human carcinoma cell line HBT-3 by iododeoxyuridine and testosterone. PMID- 4134396 TI - Detergent-solubilised H-2 alloantigen is associated with a small molecular weight polypeptide. PMID- 4134397 TI - Pulmonary hyaline membrane: light and electron microscopic study of the early stage. PMID- 4134398 TI - Spatial and temporal distribution of axonal degeneration in the primary optic system of the cat. PMID- 4134399 TI - Retrograde degeneration of primary optic fibers in the cat. PMID- 4134400 TI - The neuroglial response to injury following spinal cord transection in the goldfish. PMID- 4134401 TI - Editorial: Whipple's disease. PMID- 4134402 TI - Whipple's disease: a report of two cases. PMID- 4134403 TI - Letter: Paraproteins in malignant disease. PMID- 4134404 TI - Pneumatic compression of the calf and postoperative deep-vein thrombosis. PMID- 4134405 TI - Prevalence of bacteriuria in infants and preschool children. PMID- 4134406 TI - Effect of 15(R)15 methylprostaglandin E2 methyl ester on healing of gastric ulcers. Controlled endoscopic study. PMID- 4134407 TI - 1,25-dihydroxycholecalciferol and 1alpha-hydroxycholecalciferol in hypoparathyroidism. PMID- 4134408 TI - Seasonal variation in onset of Burkitt's lymphoma in the West Nile District of Uganda. PMID- 4134409 TI - Insecticide and viral interaction as a cause of fatty visceral changes and encephalopathy in the mouse. PMID- 4134410 TI - Inheritance of ankylosing spondylitis and HL-A antigen W27. PMID- 4134411 TI - Respiratory filters in clinical practice. PMID- 4134412 TI - An improved sampling device for cervical cytology. PMID- 4134413 TI - Editorial: Liver transplantation. PMID- 4134414 TI - Editorial: Role of the community physician. PMID- 4134415 TI - Editorial: Beware of the cow. PMID- 4134416 TI - Editorial: The lymphocyte in the gut. PMID- 4134417 TI - Editorial: Chlorpropamide in diabetic pregnancy. PMID- 4134418 TI - Editorial: tcPo2. PMID- 4134419 TI - Editorial: The relatives of schizophrenics. PMID- 4134420 TI - Live-virus vaccines in pregnancy. Risks and recommendations. PMID- 4134421 TI - Letter: Cancer of the cervix: a sexually transmitted infection? PMID- 4134422 TI - Letter: Hypoxia, saffron, and cardiovascular disease. PMID- 4134423 TI - Letter: Myopathies: the neurogenic hypothesis. PMID- 4134424 TI - Letter: Defective cellular membrane in muscular dystrophy? PMID- 4134425 TI - Letter: HL-A antigens in myasthenia gravis. PMID- 4134426 TI - Letter: HL-A-antigen segregation analysis in multiple sclerosis. PMID- 4134427 TI - Letter: American Medical Association. PMID- 4134428 TI - Letter: Blood-lead levels, behaviour, and intelligence. PMID- 4134429 TI - Letter: "Per cent T cells". PMID- 4134430 TI - Letter: Height and weight standards. PMID- 4134431 TI - Letter: Universal growth standards for preschool children. PMID- 4134432 TI - Letter: Vitamins and the elderly. PMID- 4134433 TI - Letter: Hair-colour changes in kwashiorkor. PMID- 4134434 TI - Letter: Maternal serum-alpha-fetoprotein and anencephaly. PMID- 4134435 TI - Letter: Anticonvulsants and congenital abnormalities. PMID- 4134436 TI - Letter: Prostaglandins and pre-eclampsia. PMID- 4134437 TI - Letter: Prostaglandin F2alpha and electroencephalogram changes. PMID- 4134438 TI - Letter: Detection of endotoxin. PMID- 4134439 TI - Letter: "Bronchospastic expiration". PMID- 4134440 TI - Letter: Therapeutic nutrition. PMID- 4134441 TI - Letter: Oestradiol 17beta: inhibitor of placental growth. PMID- 4134442 TI - Letter: Serum-lithium control. PMID- 4134443 TI - Letter: Amines and theories in psychiatry. PMID- 4134444 TI - Letter: Thyrotrophin-releasing hormone in depression. PMID- 4134445 TI - Letter: Upper gastrointestinal endoscopy. PMID- 4134446 TI - Letter: S.I. units. PMID- 4134447 TI - Letter: Bran hypothesis. PMID- 4134448 TI - Letter: Serum-gastrin in vitiligo. PMID- 4134449 TI - Letter: Growth-hormone response to exercise in obese children. PMID- 4134450 TI - Letter: Postoperative gynaecological wound infection. PMID- 4134451 TI - Letter: Immunotherapy with intravenous B.C.G. PMID- 4134452 TI - Letter: Cell-mediated immunity in hepatitis. PMID- 4134453 TI - Letter: Blood fractions for treatment of haemophilia. PMID- 4134454 TI - Letter: Prolactin levels in gynaecomastia related to Klinefelter's syndrome. PMID- 4134455 TI - Letter: Turner's syndrome and long-arm deletions of X chromosome. PMID- 4134456 TI - Letter: Effect of clonidine on nicotinic-acid flushing. PMID- 4134457 TI - Letter: Geriatrics is medicine. PMID- 4134458 TI - Obituary. John George Gibson. PMID- 4134460 TI - Leukemic infiltration of prostate. PMID- 4134459 TI - The innervation of the salivary gland of the moth, Manduca sexta. PMID- 4134461 TI - [Editorial: For an audiovisual policy]. PMID- 4134462 TI - Ultrastructural distribution of cell surface antigens in avian tumor virus infected chick embryo fibroblasts. AB - The distribution of neoantigens in the surface membrane of avian tumor virus infected chicken embryo fibroblasts was examined on carbon replicas of cell cultures using hemocyanin-labeled antibody. New determinants appearing on the cell surface of virally infected but not transformed cells are thought to be common with components of the viral envelope. These antigens were found to exist in a diffuse, random array on the dorsal cell surface, with a denser accumulation along the cell processes. In living cells, surface antigens are capable of several types of redistribution when activated by reaction with antibody. Leukosis virus-infected (non-transformed) cells showed two apparently independent modes of redistribution: a relocation of some antibody-related sites to the cell margin; or an involvement of essentially all sites in randomly dispersed aggregates. Viral antigenic sites on sarcoma virus-infected (transformed) cells, reacted with antibody, were able to produce weak marginal relocation; but revealed a more striking tendency to migrate to some central location. The centripetal coalescence thus formed resembles the "cap" noted in other systems. Prior aggregation into "patches" may not be a prerequisite for such cap formation. Tumor-specific surface antigen detection and mapping was attempted by this technique, but results were equivocal. An antigen possibly characteristic of rapidly dividing cells occurred in a sparse, diffuse fashion over the surface of morphologically distinct "round" cells. PMID- 4134463 TI - Temperature dependence of mast cell histamine secretion. PMID- 4134464 TI - Alpha1-fetoprotein biosynthesis during the growth cycle of differentiated fetal rat hepatocytes in primary monolayer culture. PMID- 4134465 TI - Isolation and characterization of RNA-directed DNA polymerase from a B-type RNA tumor virus. AB - RNA-directed DNA polymerase was isolated from milk-borne B-type murine mammary tumor virus of the RIII mouse strain. The several hundred-fold-purified enzyme sediments at 5.5 to 5.7S with an average molecular weight of approximately 100,000. The purified enzyme is completely template dependent and responds to RNA, DNA, and synthetic templates. Stability studies indicate differential lability dependent on the exogenous template used to monitor activity. PMID- 4134466 TI - Physical and chemical properties of an oncornavirus associated with a murine adrenal carcinoma cell line. AB - A type C oncornavirus has been isolated from a continuous cell line of murine adrenal carcinoma in culture. The particles have a buoyant density of 1.165 g/cm(3), exhibit typical type C morphology by electron microscopy, possess an RNA dependent DNA polymerase, and have a high molecular weight RNA (6.1 x 10(6)) which can be denatured to a homogeneous lower molecular weight species (3.2 x 10(6)) when extracted from rapidly harvested "immature" virions. The virus is related antigenically to other mammalian oncornaviruses and exhibits a similar, although much more complex, sodium dodecyl sulfate gel electrophoretic profile of virion proteins when compared to the profiles of other type C RNA tumor viruses. PMID- 4134467 TI - Immunological properties of two polypeptides of Mason-Pfizer monkey virus. AB - Two polypeptides were isolated from the Mason-Pfizer monkey virus (MP-MV). The polypeptides, designated MP-MV p26 and MP-MV p15, were 26,000 and 15,000 molecular weight, respectively, based on gel filtration chromatography in the presence of 6 M guanidine hydrochloride. Radioimmunoassays developed for MP-MV p26 and p15 were, respectively, 10 and 100 times more sensitive than immunodiffusion and 1 and 10 times more sensitive than micro-complement fixation for the detection of MP-MV. Antigens of other reverse transcriptase-containing RNA viruses did not cross-react in either MP-MV radioimmunoassay. Further, antisera against these other viruses did not react with the radioiodine-labeled MP-MV polypeptides. The MP-MV radioimmunoassays should be useful in studying the natural occurrence of this virus and its relationship to primate tumors. PMID- 4134469 TI - Introductory remarks for The Third James A. English Symposium. PMID- 4134468 TI - Deficiency of 60 to 70S RNA in murine leukemia virus particles assembled in cells treated with actinomycin D. AB - Production of particles with the ultrastructural appearance of C-type virions persisted for at least 6 h in actinomycin D-treated cells infected with murine leukemia virus. This phenomenon occurred despite severe inhibition of viral RNA synthesis. Virus particles present in a 6-h harvest sedimented in sucrose gradients with the buoyant density characteristic of RNA tumor viruses (1.16 g/cm(3)) and exhibited high levels of reverse transcriptase activity in response to the exogenous template polyriboadenylic acid.oligo deoxythymidylic acid in the range of untreated controls. However, RNase-sensitive endogenous activity was only (1/5) the level found in controls. This observation correlated with a marked reduction in infectivity. Kinetic studies on the appearance of labeled RNA in banded virions revealed that within the first hour after addition of actinomycin D, particles contained 60 to 70S RNA and two low-molecular-weight RNA species corresponding to 8 and 4S RNA. After approximately 1 h of incubation with actinomycin D, 60 to 70S RNA could not be detected and 4S RNA was the predominant species. These findings suggest that murine leukemia virus particles assembled in the presence of actinomycin D are deficient in 60 to 70S viral RNA. PMID- 4134470 TI - Structural proteins of mammalian oncogenic RNA viruses: murine leukemia virus neutralization by antisera prepared against purified envelope glycoprotein. AB - Goat and rabbit antisera prepared against a purified Rauscher murine leukemia virus glycoprotein (gp69/71) rapidly neutralized spleen focus-forming virus in Rauscher and Friend virus preparations. Absorption studies revealed that most of the neutralizing activity of goat anti-Rauscher virus gp69/71 serum was directed against type- and group-specific determinants. PMID- 4134471 TI - [Venous stenoses in their thoracobrachial trajectories]. PMID- 4134472 TI - Street runoff as a source of lead pollution. PMID- 4134473 TI - [Chemotaxis of human polymorphonuclear leukocytes in vitro. 1. Study of the method in normal adults]. PMID- 4134474 TI - The recognition of homologous and heterologous erythrocytes by guinea pig macrophages. PMID- 4134475 TI - Immunologically active glycopeptides derived from CEA. PMID- 4134476 TI - Relationship of skin reactive intestinal cancer antigen to the carcinoembryonic antigen of Gold and other antigens. PMID- 4134477 TI - Specificity of the carcinoembryonic antigen. PMID- 4134478 TI - Staining of biological material for the scanning electron microscope. PMID- 4134479 TI - Recent findings concerning dose response relationship in mutagenicity testing of chemicals. PMID- 4134480 TI - [Current situation and developmental trends in the field of thrombolytic agents]. PMID- 4134481 TI - Review of the biochemistry and coagulation physiology of brinolase. (Fibrinolytic enzyme from Aspergillus oryzae). PMID- 4134482 TI - [Experimental and clinical studies on a protease from Aspergillus oryzae (Brinase): fibrinogen turnover, thrombocyte aggregation and occlusion of the Scribner shunt]. PMID- 4134483 TI - [Characterization of an alkaline protease form Aspergillus ochraceus]. PMID- 4134484 TI - Studies on the proteolysis of fibrinogen and fibrin by Aspergillus ochraceus enzyme as compared to the action of plasmin. PMID- 4134485 TI - [Thrombolysis in experimental shunt loops]. PMID- 4134486 TI - [Fibrinolytic potential of the blood in liver damage]. PMID- 4134487 TI - [Electron microscopy findings in Lichen nitidus]. PMID- 4134488 TI - Histochemical studies of cartilage development in the mouse limb-bud. I. Connective tissue, RNA, and protein end-group methods. PMID- 4134489 TI - Immunology of the gastrointestinal tract. II. PMID- 4134490 TI - [Drug therapy in pacemaker patients]. PMID- 4134491 TI - Optical polarisation indicates linear arrangement of rhodopsin oligosaccharide chain in rod disk membranes of frog retina. PMID- 4134492 TI - [Radiosensitivity and cell proliferation in vitro and in vivo]. PMID- 4134493 TI - 5-Bromo-2'-deoxyuridine potentiation of transformation of rat-embryo cells induced in vitro by 3-methylcholanthrene: induction of rat leukemia virus gs antigen in transformed cells. AB - Low-passage rat-embryo cells were not transformed by 3-methylcholanthrene or by 5 bromo-2' deoxyuridine. However, prior treatment with bromodeoxyuridine, followed by treatment with methylcholanthrene, resulted in cell transformation about three subpassages after removal of the carcinogen. RNA-directed DNA polymerase activity could not be detected in either normal or transformed cells. However, gs-1 antigen specific for rat C-type RNA virus was detected in cultures derived from bromodeoxyuridine-treated cells. No gs-1 antigen for the C-type RNA virus was detected in cultures that had not been treated with bromodeoxyuridine during the 25 subpassages of these experiments.High-passage rat-embryo cells, derived from a different cell pool, were transformed by either methylcholanthrene or dimethylbenzanthracene without prior infection with an exogenous virus, and without prior treatment with bromodeoxyuridine, gs-1 antigen for C-type RNA virus was also detected in 4 of 4 randomly selected transformed cell lines; the gs-1 antigen was not detected in any of 4 nontransformed control cultures. Considering these and previously published findings, we conclude that the lowpassage cells cannot be transformed by methylcholanthrene because of powerful cellular controls over the endogenous virus. Bromodeoxyuridine triggers some expressions of the endogenous virus; thus, the bromodeoxyuridine-treated cells are more susceptible to the transforming effects of methylcholanthrene. High-passage rat cells do not maintain perfect control over expression of their endogenous virus; the cell cultures are susceptible to the transforming effects of chemical carcinogens. PMID- 4134494 TI - Measurement of serum folate levels and serum folic acid-binding protein by 3H-PGA radioassay. PMID- 4134495 TI - An improved nitroblue tetrazolium test and its correlation with toxic neutrophils. PMID- 4134496 TI - Hepatic cytopathology in alpha-1-antitrypsin (alpha-1-AT) deficiency. PMID- 4134497 TI - Letter: Celestin blue B and hematoxylin. PMID- 4134498 TI - Cystic dilatation of sex accessory organs in common and inbred Syrian Hamsters. PMID- 4134499 TI - Expression of the defective "S plus L-" type murine sarcoma virus genome in human amnion and lung cells. PMID- 4134500 TI - In vivo growth and antigenic properties of a rat sarcoma induced by Moloney sarcoma virus. PMID- 4134501 TI - Enhanced production of mouse mammary tumor virus in dexamethasone-treated, 5 iododeoxyuridine-stimulated mammary tumor cell cultures. PMID- 4134502 TI - HL-A heterozygosity as a genetic marker of long-term survival. PMID- 4134503 TI - A new routine in histopathology. PMID- 4134504 TI - The kinetics of erythrocyte lysis by Escherichia coli haemolysin. PMID- 4134505 TI - Mitomycin-induced lysis of Clostridium sordellii. PMID- 4134506 TI - Formation of "amyloid" fibrils in vitro by action of human kidney lysosomal enzymes on Bence Jones proteins. PMID- 4134507 TI - Gastric and caecal lesions in pigs following the feeding of sulphite. PMID- 4134508 TI - Experimental Escherichia coli mastitis in cattle, its pathogenisis and treatment. PMID- 4134509 TI - Biosynthetic activities of dorsal root ganglia in vitro and the influence of nerve growth factor. PMID- 4134510 TI - Low-angle x-ray diffraction studies on the period of central myelin sheaths during preparation for electron microscopy. A comparison between different anatomical areas. PMID- 4134511 TI - Fast and slow contraction times associated with fast and slow spike conduction of skeletal muscle fibres in normal subjects and in spastic hemiparesis. PMID- 4134512 TI - [Chronic secondary hypoparathyroidism in connection with a partially reversible psycho-organic syndrome (author's transl)]. PMID- 4134513 TI - [Neurophysiological aspects in carpal tunnel syndrome. Correlations with the clinical findings (author's transl)]. PMID- 4134514 TI - Electroanatomical observations on the ventro caudal parts of the thalamus according to the facts of stereotactic stimulation in man. PMID- 4134515 TI - [Gammaglobulins in cerebrospinal fluid during various stages of multiple sclerosis (author's transl)]. PMID- 4134516 TI - [Microanalysis of lipids in cerebrospinal fluid (author's transl)]. PMID- 4134517 TI - Rubella. PMID- 4134518 TI - Effects of supraoptimal temperatures on the myxomycete Physarum polycephalum. II. Effects on the rate of protein and ribonucleic acid synthesis. PMID- 4134519 TI - [Experience in the electron microscopic study of brain preparations, previously impregnated according to Golgi's method]. PMID- 4134520 TI - Cryoglobulins in glomerulonephritis not related to systemic disease. PMID- 4134521 TI - [Indicator of function of the urinary bladder]. PMID- 4134522 TI - The metabolism of porphyrins of the isocoproporphyrin series. PMID- 4134523 TI - The determination in human males of specific testosterone and 5aplha dihydrotestosterone binding to sex hormone binding globulin by a differential dissociation technique. PMID- 4134524 TI - [Possibilities of biofunctional studies of blood supply]. PMID- 4134525 TI - [The mechanism of supraventricular tachycardia]. PMID- 4134526 TI - Synchrotron radiation and its applications in biology. PMID- 4134527 TI - Relation of absorption rates of glucose, glycine and glycylglycine to serum globulin concentrations in man in vivo. PMID- 4134528 TI - Involvement of IgE in con A-induced histamine release from human basophils in vitro. PMID- 4134529 TI - The effect of nerve growth factor (NGF) upon axoplasmic transport in sympathetic neurons of the mouse. PMID- 4134530 TI - Subcellular localisation of adrenal cholesterol by autoradiography and digitonin reaction after aminoglutethimide-induced inhibiton of corticosterone synthesis. PMID- 4134531 TI - [Stimulation of gene activities by polyamines. An autoradiographic study with giant chromosones of Chironomus thummi (author's transl)]. PMID- 4134532 TI - Ultrastructure of exogenous peroxidase in cerebral cortex. PMID- 4134533 TI - Evidence for PAS positive reaction of the corticotroph granules of the rat adenohypophysis. PMID- 4134534 TI - Rohde's fiber: a septate axon in the leech. PMID- 4134535 TI - Cytoplasmic order in an invertebrate neuron. PMID- 4134536 TI - The deficient density-dependent growth control of human malignant glioma cells and virus-transformed glia-like cells in culture. PMID- 4134537 TI - Expression of fetal antigens and tumor-specific antigens in SV40-transformed cells. I. Serological analysis of the antigenic specificities. PMID- 4134538 TI - Some observations on the skeletal musculature of aged rats. I. Histological aspects. PMID- 4134539 TI - A new approach for studies on calcareous corpuscles in Hymenolepis microstoma. PMID- 4134540 TI - The HL-A system. II. Clinical relevance. PMID- 4134541 TI - Ontogenesis of sympathetic fibers after neonatal 6-hydroxydopamine treatment in the rat. PMID- 4134542 TI - Neutrophil-specific antigens: immunology and clinical significance. PMID- 4134543 TI - The cellular recognition in vitro of antigens related to human histocompatibility. PMID- 4134544 TI - Carcinoma of the lip. Analysis of the material of 25 years. PMID- 4134545 TI - [Colorimetric method of evaluating the staining of biological micropreparations]. PMID- 4134546 TI - [Human teratocarcinoma: cellular affinity labeling with tritiated estrogens]. PMID- 4134547 TI - Absence of B antibody in a blood group A person. PMID- 4134548 TI - [Role of microcoagulation in the catabolism of fibrinogen]. PMID- 4134549 TI - Combined intervention for controlling unwanted homosexual behavior. PMID- 4134550 TI - Morphological studies of Herpesvirus saimiri in primate cell cultures. PMID- 4134551 TI - A molecular theory to explain the mechanisms of allergic histamine release. PMID- 4134552 TI - Chronic plasma cell cervicitis. A rare pitfall in gynecological cytology. PMID- 4134553 TI - A description by computer of texture in Wright-stained leukocytes. PMID- 4134554 TI - The aid of some histochemical stains in the identification of mesothelial cells. Preliminary results. PMID- 4134555 TI - Diagnosis of strongyloidiasis in Papanicolaou-stained sputum smears. PMID- 4134556 TI - The morphology of Cryptococcus neoformans in human cryptococcosis. A light-,phase contrast and electron-microscopic study. PMID- 4134557 TI - Neurosecretion in the pineal gland of Macaca rhesus. PMID- 4134558 TI - Aqueous solution of acridine orange in the staining of DNA-aldehyde. PMID- 4134559 TI - [Recent findings on the lymphocytic system in man. II. Characterization of human T and B lymphocytes and their significance in medical practice (author's transl)]. PMID- 4134560 TI - [Hemotherapy in due proportion. II. Clinical administration of plasma fractions]. PMID- 4134561 TI - Synergia of a heparinoid and promethazine hydrochloride against liver cell necrosis. PMID- 4134562 TI - The effects of age and exercise on the succinic dehydrogenase content of individual muscle fibres from fast, slow and mixed hamster muscles. PMID- 4134563 TI - Glucose-6-phosphatase heterogeneity within the hepatic lobule of the phenobarbital-treated rat. PMID- 4134564 TI - Prevention by aging or by cytochalasin B of phalloidin stimulated formattion of microfilaments in cell membrane preparations of rat liver. PMID- 4134565 TI - Peroxidase and amylase activity of the guinea pig submandibular gland during the secretory cycle. An electronhistochemical and biochemical study. PMID- 4134566 TI - Expression of the major group-specific antigen (GS-A) of avian type-C viruses in normal chicken cells and tissues. PMID- 4134567 TI - Expression of fetal antigens and tumor-specific antigens in SV40-transformed cells. II. Tumor transplantation studies. PMID- 4134568 TI - [Fractionation and purification of allergenic extracts most commonly responsible for allergic bronchial asthma. Study of immunologic response in atopic patients]. PMID- 4134569 TI - [Neonatal candidosis with meningitis in a premature infant]. PMID- 4134570 TI - Histochemistry of primate extraocular muscles and the changes of denervation. PMID- 4134571 TI - An outer membrane protein of Neisseria meningitidis group B responsible for serotype specificity. AB - Meningococcal groups B and C have been subdivided into a series of serotypes based upon the antigenic specificity of protein serotype antigens (STA). The purpose of these studies was to obtain the STA by gentle methods and determine its anatomic location in the meningococcal cell. The STA was extracted from group B meningococcal strains by either 0.2 M LiCl or 0.2 M CaCl(2) and isolated from the extracts by gel filtration on Sepharose 6B or by pelleting the STA by centrifugation at 100,000 g. The isolated STA was a lipoprotein lipopolysaccharide complex with a mol wt of approximately 4 x 10(6) daltons. Antisera prepared against the type 2 STA were bactericidal only for homologous serotype strains. The STA proved to be a constituent of the outer membrane of the cell envelope. This was shown by SDS-polyacrylamide gel electrophoresis (PAGE) of the isolated outer membrane and of the purified STA. The type 2 STA complex contains three principal proteins, one of which is predominant with a mol wt of 41,000 daltons. The type 2 STA was dissociated by Triton X-100 and separated by sucrose gradient isodensity centrifugation into two peaks. The denser peak (rho = 1.26 g/cm(3)) contained the majority of the 41,000 dalton major outer membrane protein as shown by SDS-PAGE. This peak also contained the type 2 antigenic determinant. Thus the major outer membrane protein, extracted as part of a lipoprotein-lipopolysaccharide complex, contains the type 2 STA determinant. PMID- 4134572 TI - Effect of chronic sulfur dioxide inhalation on the carbohydrate histochemistry and histology of the canine respiratory tract. PMID- 4134573 TI - Cutaneous localization of human gamma-globulins in lupus erythematosus. An electron-microscopical study using the peroxidase-labeled antibody technique. PMID- 4134574 TI - Degradation of dyfonate in soil inoculated with Rhizopus arrhizus. PMID- 4134575 TI - A modified assay for the Waaler-Rose test using latex particles coated with rabbit gamma-globulins. PMID- 4134576 TI - [A new device for information and education of the patient]. PMID- 4134577 TI - [Effect of chlormadinone acetate on the activity of various liver enzymes in newborn rabbits]. PMID- 4134578 TI - Incorporation of exogenous DNA into mammalian chromosomes. PMID- 4134579 TI - A glycogen-rich segment of the tubuli recti and proximal portion of the rete testis in the guinea-pig. PMID- 4134580 TI - Proteins and amino acids in bovine oviducal fluid. PMID- 4134581 TI - Staphylococcal heat-stable opsonins. PMID- 4134582 TI - Fractionation of bee venom. I. Preparation and characterization of four antigenic components. PMID- 4134583 TI - The exudative lesions in diabetic retinopathy with special regard to the hard exudate. PMID- 4134584 TI - Spontaneous regression of a malignant melanoma of the choroid. PMID- 4134585 TI - Benign mucous membrane pemphigoid. 1. Secretion of mucus and tears. PMID- 4134586 TI - Benign mucous membrane pemphigoid. II. Cytology. PMID- 4134587 TI - [Immunoglobulin levels in sarcoidosis (author's transl)]. PMID- 4134588 TI - [Post-mortem investigation of occult thyroid carcinoma in endemic goitre regions (author's transl)]. PMID- 4134589 TI - Differential light scattering from spherical mammalian cells. AB - The differential scattered light intensity patterns of spherical mammalian cells were measured with a new photometer which uses high-speed film as the light detector. The scattering objects, interphase and mitotic Chinese hamster ovary cells and HeLa cells, were modeled as (a) a coated sphere, accounting for nucleus and cytoplasm, and (b) a homogeneous sphere when no cellular nucleus was present. The refractive indices and size distribution of the cells were measured for an accurate comparison of the theoretical model with the light-scattering measurements. The light scattered beyond the forward direction is found to contain information about internal cellular morphology, provided the size distribution of the cells is not too broad. PMID- 4134590 TI - Photoreactivation and excision repair of ultraviolet radiation-injured DNA in primary embryonic chick cells. AB - Primary embryonic chick cells have been evaluated on the basis of their capacity to repair photochemical lesions produced in the deoxyribonucleic acid (DNA) by ultraviolet (UV) radiation. The fate of one prominent class of UV photoproducts, cyclobutane pyrimidine dimers, was monitored by an in vitro enzymatic assay. UV irradiated cultures were incubated for prescribed times after which their damaged, radioactive-labeled DNA was extracted and exposed to a purified UV endonuclease selectively active toward sites altered by dimer formation. Single strand scissions specifically introduced by the enzyme treatment and, therefore, the dimer-containing sites remaining in the DNA were quantified retrospectively by velocity sedimentation in alkaline sucrose. When the chick fibroblasts were incubated in black light, essentially all nuclease-susceptible sites rapidly disappeared from the UV-damaged DNA. In sharp contrast, incubation of the irradiated cultures in total darkness severely impeded the metabolic machinery responsible for site elimination. A substantial amount of UV-stimulated DNA repair synthesis was also detected in the chick cells by conventional techniques involving isopyknic centrifugation and autoradiography. However, the UV photoproducts triggering this indicator of excision repair were probably not dimers since incubation of the irradiated cultures in the light rather than in the dark did not lead to a diminution in the extent of repair synthesis. By these criteria of DNA repair, it appears that embryonic chick cells primarily rely on a highly proficient, light-requiring mechanism, presumably enzymatic photoreactivation, for dimer elimination but also possess a light-independent, excision-type process to cope with other, as yet unidentified, photochemical defects. PMID- 4134591 TI - Glycogen storage and depletion in human skeletal muscle fibres. PMID- 4134592 TI - [Use of new educational technology in the development of human resources]. PMID- 4134593 TI - Active and passive cutaneous anaphylaxis in the horse following immunization with benzylpenicilloyl-bovine gamma globulin (BPO20-BGG). PMID- 4134594 TI - The clinical course associated with dense deposits in the kidney basement membranes. PMID- 4134595 TI - [Disorders of rhythm and conduction in ischemic heart disease]. PMID- 4134596 TI - [Antigenic similarities of certain Salmonella O:54 serotypes with other O groups of the Kaufmann-White outline]. PMID- 4134597 TI - Linear polypeptides of a known primary structure. Synthesis and immunochemical studies of poly(O-methyl-L-tyrosy-L-glutamyl-L-alanylglycyl)glycine-1-14C ethyl ester. PMID- 4134598 TI - [Antimetabolites in the treatment of acute human leukoses. Mechanism of action and conditioning factors in the cellular response to drugs. II]. PMID- 4134599 TI - [Intestinal lipodystrophy (Whipple's disease) diagnosed during life]. PMID- 4134600 TI - [On the 250th anniversary of the USSR Academy of Sciences. Scientific studies at the Academy of Sciences--theoretical basis for laboratory diagnosis]. PMID- 4134601 TI - [Cytological method of diagnosis of tumors and tumor-like formations of the jaws]. PMID- 4134602 TI - [Column for preparative separation of ribonucleic acids and other biological compounds by the method of polyacrylamide gel electrophoresis]. PMID- 4134603 TI - [Value of the bacterioscopic method of study in the present-day course of gonorrhea]. PMID- 4134604 TI - [Future development of laboratories in Sanitary-Epidemiological Stations]. PMID- 4134605 TI - [Pigment formation in staphylococci on a medium with bile]. PMID- 4134606 TI - Insulin degradation by fat cell ghosts. PMID- 4134607 TI - The adsorption of some proteins on hydroxylapatite and other absorbents used for chromatographic separations. PMID- 4134608 TI - The translation of mouse globin mRNA from which the polyadenylic acid sequence has been removed in a reinitiating protein synthesis system. PMID- 4134609 TI - The subunit-structure of the uterine "oestradiol-receptor". PMID- 4134610 TI - A test of models of membrane structure by molecular hybridization. PMID- 4134611 TI - [Determination of thyroid hormone-induced metabolic conditions using the T4 and T3 tests with reference to radioiodine therapy]. PMID- 4134612 TI - [Comparative toxic and therapeutic effects of adriamycin and bleomycin in malignant lymphoma (author's transl)]. PMID- 4134613 TI - [Immunological diagnosis of Larva migrans visceralis infection caused by Toxocara canis (author's transl)]. PMID- 4134614 TI - [Aberration of conduction. Differential diagnosis and significance of intermittently occurring spreading ventricular complexes in electrocardiogram]. PMID- 4134615 TI - [Special mechanism of action of Freund's and Berrens' adjuvants]. PMID- 4134616 TI - Separation of ribonuclease H and RNA directed DNA polymerase (reverse transcriptase) of murine type-C RNA tumor viruses. AB - Ribonuclease H (RNA.DNA-hybrid ribonucleotidohydrolase, EC 3.1.4.34) has been reported to copurify with reverse transcriptase (RNA directed DNA polymerase) of RNA tumor viruses. In addition, viral specific ribonuclease H and reverse transcriptase of avian type-C viruses are thought to be part of the same polypeptide. In this report we show that a fraction of the ribonuclease H activity from Rauscher murine leukemia and Kirsten murine sarcoma viruses was separated from reverse transcriptase by anion exchange chromatography while the remaining portion co-purified with the viral polymerase. The amount of this co purified nuclease activity was about 4- to 8-fold lower than the activity found in avian myeloblastosis virus (with respect to the ratio of ribonuclease H to reverse transcriptase) and this nuclease activity can only be detected by using labeled substrate of high specific radioactivity. However, a complete separation of ribonuclease H activity from reverse transcriptase was obtained by purifying core structures of the virus by sucrose density gradient centrifugation. While reverse transcriptase was present in the cores, there was no detectable ribonuclease H. Furthermore, a specific antibody against Rauscher leukemia virus reverse transcriptase did not inhibit any virion associated ribonuclease H activity. Our results suggest that in these virions these two enzyme activities reside in two separate molecules and probably in two different compartments of the virus. These findings emphasize a basic difference between the avian and murine type-C virus DNA polymerases. PMID- 4134617 TI - RNA-dependent DNA polymerase (reverse transcriptase) from avian myeloblastosis virus: a zinc metalloenzyme. AB - RNA tumor viruses contain a characteristic RNA-dependent DNA polymerase (reverse transcriptase) which has been thought to be related to the induction of leukemia by this virus. A disturbance in a zinc-dependent enzyme system was first postulated to account for the demonstrated differences in zinc metabolism of normal and leukemic leukocytes [Vallee et al. in (1949) Acta Unio. Int. Contra Cancrum 6, 869 and (1950) Acta Unio. Int. Contra Cancrum 6, 1102]. In order to investigate the relationship between zinc and the initiation of leukemia in chickens by avian myeloblastosis virus, we have examined the metalloenzyme nature of its reverse transcriptase. The present data show that this protein is a zinc metalloenzyme demonstrating the postulated relationship between zinc and a leukemic process. Paucity of purified enzyme generated the design of a novel system of analysis incorporating microwave-induced emission spectrometry combined with gel exclusion chromatography. It provides precision, reproducibility, and remarkable limits of detection on mul samples containing 10(-12) to 10(-14) g atoms of metal, and is thus orders of magnitude more sensitive than other methods. The chromatographic fraction with highest enzymatic activity contains 1.8 x 10(-11) g-atoms of zinc per 1.6 mug of protein, corresponding to either 1.8 or 2.0 g-atoms of zinc per mole of enzyme for a molecular weight previously determined either as 1.6 or 1.8 x 10(5). Copper, iron and manganese are absent, i.e., at or below the limits of detection, 10(-13) to 10(-14) g-atoms. Agents known to chelate zinc inhibit the enzyme, while their nonchelating isomers do not. The data underline the participation of zinc in nucleic acid metabolism and bear importantly upon the lesions that accompany leukemia and zinc deficiency. PMID- 4134618 TI - [Cytostatic treatment of liver cancer]. PMID- 4134619 TI - [Battered child syndrome]. PMID- 4134620 TI - Craniorachischisis in a partially trisomic 11 fetus in a family with reproductive failure and a reciprocal translocation, t(6p plus;11q minus). PMID- 4134621 TI - Immunoglobulins. PMID- 4134622 TI - Double autosomal trisomy and mosaicism for chromosomes no. 8 and no. 21. PMID- 4134623 TI - Presumptive mosaic partial trisomy associated with congenital anomalies and mental deficiency. PMID- 4134624 TI - Variations in normal human chromosomes. PMID- 4134625 TI - Acrocentric associations in mongol populations. PMID- 4134626 TI - Autosomal deletions 46,XY,del(12)(p11) and 46,XY-46,XY,del(5)(p13) with no effect on physical or mental development. PMID- 4134627 TI - Chromosome banding patterns in an infant with 13q minus syndrome. PMID- 4134628 TI - Identification of a 18-21 translocation with Klinefelter's syndrome by G-band patterns. PMID- 4134629 TI - Investigation of some biochemical genetic markers in four endogamous groups from Panjab (N. W. India). I. Protein and enzyme polymorphisms in serum. PMID- 4134630 TI - Evidence for an unlinked gene which modifies HL-A antigen expression. PMID- 4134631 TI - An (11;21) translocation in four generations with chromosome 11 abnormalities in the offspring. A clinical, cytogenetical, and gene marker study. PMID- 4134632 TI - The penetration of bacteria into experimentally exposed human coronal dentin. PMID- 4134633 TI - [Research into the biochemical bases of schizophrenic syndromes: a review]. PMID- 4134634 TI - [Treatment of thromboembolic conditions with thrombolytics and anticoagulants]. PMID- 4134635 TI - [Papanicolaou's staining method extended to semen studies]. PMID- 4134636 TI - Primary carcinoma of the liver. PMID- 4134637 TI - Simple mastectomy for early and advanced mammary carcinoma. PMID- 4134638 TI - Humoral immunity in chronic liver disease. PMID- 4134639 TI - [Immunoglobulin synthesis in mixed cultures of lymph node and bone marrow cells, obtained from immune donors]. PMID- 4134640 TI - Antibodies to BSA conjugates of morphine derivatives: strict dependency of the immunological specificity on the hapten structure. PMID- 4134642 TI - Approaches to alcholism in mid-Victorian England. PMID- 4134641 TI - [Hyrtl versus Brucke. A scholarly dispute of the nineteenth century and its background]. PMID- 4134643 TI - Anton Storck (1731-1803) and British therapeutics. PMID- 4134644 TI - [The origins of blood transfusion. I]. PMID- 4134645 TI - [Anti-arrhythmia agents]. PMID- 4134647 TI - Teaching aid: a practical method of demonstrating intensifying screen response. PMID- 4134646 TI - [Treatment of cardiac arrhythmias with N-propyl-ajmalinium-hydrogentartrat (Neo Gilurytmal (author's transl)]. PMID- 4134648 TI - HL-A antigens and disease. Statistical and genetical considerations. PMID- 4134649 TI - Beta2-microglobulin on the cell surface. Relationship to HL-A antigens and the mixed leucocyte culture reaction. PMID- 4134650 TI - [Cellular immune reaction against aggregated human gamma globulin in chronic polyarthritis]. PMID- 4134651 TI - [Quantitative determination of C-reactive protein in progressive chronic polyarthritis]. PMID- 4134652 TI - [Manifestation joint in degenerative bone diseases]. PMID- 4134653 TI - 1974 National Children's Dental Health Week. Bureau of Dental Health Education. PMID- 4134654 TI - [Chlamydia trachomatis study. Morphological variation of the etiological agent of trachoma in cell cultures]. PMID- 4134655 TI - Structure and activity of hepatitis B antigen (HBAg). 1. Studies on some conformational aspects and chemical modification of hepatitis B antigen. PMID- 4134656 TI - Colpomicroscopy: basic outlines, technique, application, diagnostics. PMID- 4134657 TI - Renewal rate of human sebaceous glands. PMID- 4134658 TI - Incidence of circulating antibodies reactive with basal cells of skin in drug reactions. PMID- 4134659 TI - Chronic mucocutaneous candidiasis, dermatophytosis and defective cellular immunity in monozygotic twins. PMID- 4134660 TI - Effects of ultraviolet irradiation on human skin lipids. In vivo and in vitro studies. PMID- 4134661 TI - Histochemical demonstration of thyrotropic and gonadotropic cells in the pituitary gland of the rat by the use of a lead tetraacetate-sodium bisulphite technique. PMID- 4134662 TI - Localization of free sulphydryl groups by ferricyanide reduction in developing conidiophores of Aspergillus nidulans. PMID- 4134663 TI - [The first tuberculosis cures with conteben--25 years later. The beginning of antimycobacterial therapy]. PMID- 4134664 TI - A new variant of Sandhoff's disease. PMID- 4134665 TI - [Interferometric determination of larusan, tibon and ethoxyd in preparations and drug forms]. PMID- 4134666 TI - [8 years of the intensive care unit in a 440-bed hospital]. PMID- 4134667 TI - Gel chromatography of thyroidal iodo-compounds on sephadex G-10. Separation of iodopeptides, iodine, 3-monoiodotyrosine, 3,5-diiodotyrosine and iodothyronines. PMID- 4134668 TI - Acid soluble nuclear proteins of rat liver: differential absorbance of bound dyes and changes in neoplasia. PMID- 4134669 TI - [Determinations of PBI and T3]. PMID- 4134670 TI - Proceedings: Influence of histamine releasing agents on tetragastrin-stimulated acid secretion of isolated bullfrog gastric mucosa. PMID- 4134671 TI - Simultaneous determination of particulate and molecular lead in the atmosphere. PMID- 4134672 TI - [Comparative evaluation of different methods of detecting leukocyturia]. PMID- 4134673 TI - Gangliosidosis (GM1). A re-evaluation of the vertebral deformity. PMID- 4134674 TI - Cell-mediated immunity to Friend virus-induced leukemia. PMID- 4134675 TI - Manipulating the patient. A comparison of the effectiveness of physician and chiropractor care. PMID- 4134676 TI - Letter: Diabetic ketoacidosis and intracerebral thrombosis. PMID- 4134677 TI - Letter: G.A.B.A. in Huntington's chorea. PMID- 4134678 TI - Letter: Propranolol and thyroidectomy. PMID- 4134680 TI - Plasma cell leukemia. Unassembled light and heavy chains in the urine. PMID- 4134681 TI - Increased urinary albumin-excretion rate in benign essential hypertension. PMID- 4134682 TI - Editorial: Universities and medical schools. PMID- 4134683 TI - Editorial: Pathologists at the crystal ball. PMID- 4134684 TI - Editorial: Defibrination with head injury. PMID- 4134685 TI - The lymphocyte in chronic lymphatic leukaemia. PMID- 4134686 TI - Geriatric psychiatry in the general hospital. PMID- 4134687 TI - Epidemic of postoperative wound infection associated with ungloved abdominal palpation. PMID- 4134688 TI - Letter: Tuberculosis retreats--slowly. PMID- 4134689 TI - Letter: Possible evidence for Xp plus in and XX Male. PMID- 4134690 TI - Letter: Neonatal deaths and sex-chromosome anomalies. PMID- 4134691 TI - Letter: Chloramphenicol. PMID- 4134692 TI - Letter: Suprastriate hemianopia. PMID- 4134693 TI - Letter: Effect of prostaglandin E2 therapy on the cerebral cortex. PMID- 4134694 TI - Letter: Prostaglandins and induction of labour. PMID- 4134695 TI - Letter: A.H.H. inducibility and lung cancer. PMID- 4134696 TI - Duration of treatment of phenylketonuria. PMID- 4134697 TI - Letter: Hospital service for children with infective diseases. PMID- 4134698 TI - Letter: Complement components in cystic fibrosis. PMID- 4134699 TI - Letter: Has anyone seen Betty? PMID- 4134700 TI - Letter: Glucagon in treatment of acute pancreatitis. PMID- 4134701 TI - Letter: S.I. units. PMID- 4134702 TI - Letter: Cellular immune responsiveness in cigarette smokers. PMID- 4134703 TI - Letter: Judging clinical competence. PMID- 4134704 TI - Letter: A.F.P. and ataxia-telangiectasia. PMID- 4134705 TI - Letter: Geriatrics is medicine. PMID- 4134707 TI - Letter: Burkitt's lymphoma. PMID- 4134706 TI - Letter: Oral contraceptives and vitamin nutrition. PMID- 4134708 TI - Letter: Seasonal variations in serum 25-hydroxycholecalciferol. PMID- 4134709 TI - Letter: Birth defects and oral hormone preparations. PMID- 4134710 TI - Letter: Unusual intranuclear filaments in multiple-sclerosis brain. PMID- 4134711 TI - Letter: Prolactin and hypercalcaemia. PMID- 4134712 TI - Proceedings: Long-term radiological assessment of juvenile rheumatoid arthritis. PMID- 4134713 TI - Terminal deoxynucleotidyltransferase in murine plasmocytomas. PMID- 4134714 TI - A glucagonoma syndrome. PMID- 4134715 TI - Treatment of uraemic pericarditis by anterior pericardiectomy. PMID- 4134716 TI - Assessment of response to treatment in advanced breast cancer. British Breast Group. PMID- 4134717 TI - Letter: B lymphocytes in inflammatory bowel disease. PMID- 4134718 TI - Letter: Lymphocyte response after radiotherapy. PMID- 4134719 TI - Letter: Propranolol in migraine. PMID- 4134720 TI - Simple rheumatoid agglutination test with non-diluted serum and blood. PMID- 4134721 TI - Proceedings: Stimulation of penicillin-sensitive lymphocytes by antigenic determinants covalently bound to cell membranes. PMID- 4134722 TI - [Proteinocholia]. PMID- 4134723 TI - [Post-coarctectomy syndrome with transition into a blind loop syndrome as an unusual complication following resection of an aortic isthmus stenosis]. PMID- 4134724 TI - Polymers as surgical implants. PMID- 4134725 TI - [Present-day data on changes in protein metabolism in malignant diseases of the blood]. PMID- 4134727 TI - Identification of cells in primate bone marrow resembling the hemopoietic stem cell in the mouse. PMID- 4134726 TI - Adrenal corticosteroids enhance production of type-C virus induced by 5-iodo-2' deoxyuridine from cultured mouse fibroblasts. AB - Induction of RNA "tumor" viruses by 5-iodo-2'-deoxyuridine in mouse fibroblasts is stimulated 5- to 25-fold by glucogenic adrenal corticosteroids. Enhancement of virus production by the hormones is inhibited by low concentration of cordycepin, an inhibitor of poly(A) synthesis. PMID- 4134728 TI - Histochemical staining patterns of muscle fibres in the gastrocnemius, soleus and anterior tibial muscles of the adult cat, as viewed in serial sections stained for lipids and succinic dehydrogenase. PMID- 4134729 TI - [Problems of the diagnosis of bullous dermatitis (apropos of 3 cases)]. PMID- 4134730 TI - Irradiation of epidermal cell suspensions in the presence and absence of protoporphyrin. PMID- 4134731 TI - A negative staining-carbon film technique for studying viruses in the electron microscope. I. Preparative procedures for examining icosahedral and filamentous viruses. PMID- 4134732 TI - Trophic influence of nerves on the development and maintenance of sensory receptors. PMID- 4134733 TI - Con A differentiates among grass pollens by binding specifically to wall glycoproteins and carbohydrates. PMID- 4134734 TI - Autogenous vein grafts in experimental canine atherosclerosis. Their fate in the abdominal aorta and peripheral arteries. PMID- 4134735 TI - Immunological cross-reactions of sulfobenzyylpenicillin. PMID- 4134736 TI - Differential inhibition of transcriptions catalyzed by T7-specific and Escherichia coli RNA polymerases by bleomycin. PMID- 4134737 TI - The effect of bleomycin on SV40 DNA: characteristics of bleomycin action which produces a single scission in a superhelical form of SV40 DNA. PMID- 4134738 TI - Interactions of DNA with zorbamycin, phleomycin and bleomycin; ultraviolet absorption and circular dichroism measurements. PMID- 4134739 TI - Effects of bleomycin on PHA-stimulated lymphocytes and isolated hepatic nuclei. PMID- 4134740 TI - Baboon virus isolate M-7 with properties similar to feline virus RD-114. AB - A virus (M-7) isolated from baboon placental tissue demonstrates many similarities to endogenous feline virus RD-114. Immunodiffusion analysis shows a group-specific antigen (gs-1) line of identity between M-7 and RD-114. Anti-RD 114 DNA polymerase IgG inhibits M-7 polymerase by 57% compared to 97% for RD-114. M-7 virus has helper activity as demonstrated by rescue of murine sarcoma virus (MSV) from sarcoma-positive leukemia-negative human amnion cells. The host range of the rescued M-7 pseudotype of MSV, MSV (M-7), is similar to that of RD-114 virus. MSV (M-7) is also able to transform baboon cells and causes no detectable transformation of feline cells without addition of helper feline leukemia virus. Interference properties of M-7 and RD-114 virus are identical. Virus-specific neutralizing antisera, although partially cross-reacting, can distinguish MSV (M 7) from MSV (RD-114). These similarities and differences between RD-114 and M-7 viruses are best explained as type-specific differences between two viruses within the same strain. PMID- 4134741 TI - A method for detecting Ig rheumatoid factors in seronegative rheumatoid arthritis. PMID- 4134742 TI - Pathomorphology and serum protein electrophoresis in animals intensively stimulated with thphoid fever vaccine. PMID- 4134743 TI - Mastocytes and some biologically active compounds in experimental trichinellosis. PMID- 4134744 TI - Comparison of morphological and physico-chemical properties of flagella and flagellins of Proteus mirabilis and its R mutant. PMID- 4134745 TI - Axoplasmic transport. PMID- 4134746 TI - [Nursing of patients following intra-ocular operations]. PMID- 4134747 TI - Amine-producing endocrine-like cells in the epithelium of urethra and prostate of the guinea-pig. A chemical, fluorescence histochemical, and electron microscopic study. PMID- 4134748 TI - Immunological studies of membrane glycoproteins isolated from human breast carcinomas. PMID- 4134749 TI - Metachromatic staining of basic nucleoproteins in chronic erythremic myelosis. PMID- 4134750 TI - Functional black adenoma of the adrenal cortex. A rare cause of primary aldosteronism. PMID- 4134751 TI - The chicken A-1 protein. Phylogenetic variation in the amino acid sequence of the encephalitogenic site. PMID- 4134752 TI - Structural studies on chick embryonic hemoglobins. PMID- 4134753 TI - Ultrastructure of 90Sr induced osteosarcomas and early phases of their development. PMID- 4134754 TI - [Detection of erythrocytic antigen A by electron microscopy]. PMID- 4134755 TI - To the memory of professor A. Biemond. PMID- 4134756 TI - [Sudanophilic (mitochondria) myopathy (author's transl)]. PMID- 4134757 TI - Vaccinia antibodies in cerebrospinal fluid of patients with multiple sclerosis. PMID- 4134758 TI - The prophylactic and therapeutic uses of immunoglobulin in virus infections. PMID- 4134759 TI - Encapsulation of lymphocyte DNA by vesicular stomatitis virus. AB - Vesicular stomatitis virus, grown on the WIL(2)-3A line of continuously growing human lymphocytes, contains DNA in addition to the viral RNA. By contrast, virus grown on BHK 21-C13 fibroblasts has no detectable DNA. The virus-associated DNA is found in both the B and T particles of the virus and is resistant to deoxyribonuclease. The DNA is intimately associated with the virus and appears to be incorporated into the viral ribonucleoprotein core structure produced by treatment of the virus with Nonidet P40 follow edby CsCl isopycnic banding. The virus-associated DNA has an isopycnic density of 1.699 g x cm(-) (-3) in CsCl, identical to that of human DNA. The average molecular weight of the DNA molecules associated with the virus is 9.0 x 10(5), as determined by velocity sedimentation in sucrose density gradients and studies of its contour length in the electron microscope. DNA.DNA reassociation kinetics of this DNA demonstrate that the DNA is of host origin and rules out the possibility that it originates from contaminating microorganisms or mitochondria. The analytical complexity of the virus-associated DNA shows that 50% of the virus-associated DNA sequences are homologous to the repeated DNA sequences of human DNA and the remaining 50% are homologous to human unique sequences. On the average, there is one molecule of DNA for each four virion particles. PMID- 4134760 TI - NS-1 (nervous system antigen-1), a glial-cell-specific antigenic component of the surface membrane. AB - A methylcholanthrene-induced glioblastoma of the C57BL/6 inbred mouse strain was used to raise antibodies in C57BL/6 and C57BL/10 inbred mice and in (C57BL/6 x DBA/2) and (C57BL/6 x Balb/c) F(1) hybrids. When examined by the cytotoxicity test, these antibodies define a cell-surface component (or components) found exclusively on brain tissue of all mouse strains studied and of several other mammalian species including man. The antigen, named NS-1 (nervous system antigen 1), is present on cells of three of the four mouse-glial-cell tumors tested, but not on the C1300 neuroblastoma, a tumor of neuronal origin. NS-1 occurs in higher concentration in regions of the nervous system richer in white than in gray matter, and in lower than normal concentrations in brains of myelindeficient neurological mutant mice. The concentration of NS-1 gradually increases postnatally and reaches the adult level between the third and fourth week. The existence of more than one allele or genetic locus controlling NS-1 activity is suggested by the occurrence of higher amounts of NS-1 in brains of the A and C57BL/6 than of the Balb/c and DBA/2 mouse strains. NS-1 is the first cellsurface component to be described that is not only unique to nervous tissue, but specific for glial cells. PMID- 4134762 TI - Intracellular localization of gastrin in the canine antral mucosa by the immunoenzyme technique. PMID- 4134761 TI - Immunological identity of the small subunit of HL-A antigens and beta2 microglobulin and its turnover on the cell membrane. AB - A number of immunological methods have been employed to show that the small subunit of HL-A antigens, isolated either after papain treatment or after solubilization with detergent, is identical to beta(2)-microglobulin, a protein previously isolated from human urine and shown to be homologous in structure to constant region domains of immunoglobulins. Moreover, quantitative data indicate virtually total identity between the small subunit of HL-A antigens and beta(2) microglobulin. Studies of the turnover of labeled HL-A antigens from the lymphocyte surface indicate that the two subunits turn over at similar rates, although only the small subunit could be detected in the culture medium. The significance of these observations is discussed. PMID- 4134763 TI - [Immune deficiencies in children]. PMID- 4134764 TI - [Leukocyte volume in the differentiation of acute leukemias]. PMID- 4134765 TI - [Experimental respiratory distress syndrome following injection of anti-lung serum. II. Morphological, biochemical, physical chemical, and immunological findings]. PMID- 4134766 TI - Tubocurarine requirements and plasma protein concentrations in the newborn infant. PMID- 4134767 TI - Sjogren's syndrome in progressive systemic sclerosis (scleroderma). PMID- 4134768 TI - The distribution of x-ray induced chromosomal abnormalities in rat kangaroo (Potorous tridactylis) cells in vitro. PMID- 4134769 TI - [Degradation of chlorinated benzenes, phenols and cyclohexane derivatives by benzene and phenol utilizing soil bacteria under aerobic conditions (author's transl)]. PMID- 4134770 TI - Axonal transport of newly synthesized glycoproteins in a single identified neuron of Aplysia californica. AB - Increasing amounts of glycoprotein synthesized from L-[(3)H]fucose injected into the cell body of R2, an identified Aplysia neuron, were found in the right pleuro abdominal connective. Autoradiography revealed that the glycoproteins were localized in the axon of R2. Glycoproteins appearing in the axon presumably were synthesized in the cell body, since no significant incorporation was observed when [(3)H]fucose was injected directly into the axon. [(3)H]glycoproteins were detected in the connective after a delay of 1 h after intrasomatic injection. Thereafter, transport from the cell body was rapid, and by 10 h after injection, 45% of the total neuronal [(3)H]glycoprotein had appeared in the axon. By analysing the radioactivity in cell body and connective 4, 10, and 15 h after injection, we found that [(3)H]glycoproteins were transported selectively compared to nonmacromolecular material. Sequential sectioning of the connective revealed that [(3)H]glycoproteins were transported in discrete waves. The population of membrane-associated [(3)H]glycoproteins in the axon differed from that in the cell body. Two of the five somatic components appeared to be transported preferentially. In addition a new component appeared in the axon 10 h after injection. PMID- 4134771 TI - Effects of Ca2+ and Mg2+ on rapid axonal transport of proteins in vitro in frog sciatic nerves. PMID- 4134772 TI - Immediate hypersensitivity and periodontal disease. PMID- 4134773 TI - Effects of serum lipoproteins on the morphology, growth, and metabolism of arterial smooth muscle cells. PMID- 4134774 TI - Affinities of progestogen and estrogen receptors in rabbit uterus for synthetic progestogens. PMID- 4134775 TI - Patient care, education, and research in pathology. PMID- 4134776 TI - PAS-bisulfite stain for diabetic angiopathy. PMID- 4134777 TI - Separation of single-stranded ribonucleic acids by acrylamide-agarose-urea gel electrophoresis. PMID- 4134778 TI - Focal and segmental sclerosing glomerulopathy (-nephritis). PMID- 4134779 TI - Histochemical and electron microscopic observations on the development, neural control and function of the Paneth cells of the mouse. PMID- 4134780 TI - Induction of ethylmorphine demethylation and aniline p-hydroxylation by various catatoxic steroids in regenerating rat liver. PMID- 4134781 TI - Immunochemical and enzymic properties of the electric eel acetylcholinesterase antiacetylcholinesterase system. PMID- 4134782 TI - X-XY mosaicism with short y. PMID- 4134783 TI - Muscle histology in fetuses at risk for Duchenne muscular dystrophy. PMID- 4134784 TI - Selective roles of thymus-derived lymphocytes in the antibody response. I. Differential suppressive effect of carrier-primed T cells on hapten-specific IgM and IgG antibody responses. AB - Passively transferred thymocytes and spleen cells from donors primed with keyhole limpet hemocyanin (KLH) exerted differential suppressive effect on IgM and IgG antibody responses of syngeneic recipients immunized with DNP-KLH depending primarily on the time when KLH-primed cells were transferred. This was demonstrated by the decrease in the numbers of DNP-specific direct and indirect PFC in the spleen of the recipients given KLH-primed cells at different times during primary and secondary immunization. Whereas the cell transfer simultaneously with or 2 days after the primary immunization produced only slight suppression of the peak IgM antibody response, it caused profound suppression of late IgM and IgG antibody responses. By contrast, the cell transfer 3 days after the immunization produced immediate suppression of the ongoing IgM antibody response resulting in its earlier termination, while being unable to prevent the induction of IgG antibody response. KLH-primed cells could moderately suppress the secondary anti-DNP antibody response, in which IgG antibody response was found to be slightly more sensitive than IgM antibody response to the suppressive influence of KLH-primed cells. The suppressive effect of the KLH-primed spleen cells was completely eliminated by the in vitro treatment of the cells with anti theta and C before cell transfer, indicating that cells responsible for the suppression are, in fact, T cells. The suppression of DNP-specific antibody response by KLH-primed T cells was achieved only if the recipients were immunized with DNP-KLH but not with DNP-heterologous carrier, suggesting that direct interaction between T and B cells is necessary for the suppression of the antibody response. It is concluded that susceptibility of B cells to the specific suppressive influence of T cells is inherently different depending on the differentiation stage of B cells and on the immunoglobulin class they are destined to produce. PMID- 4134785 TI - Influence of a combined oral contraceptive upon rats fed low protein-high carbohydrate diets. PMID- 4134786 TI - Primary and secondary cerebrospinal fluid acidosis as a manifestation of cerebral lesions. PMID- 4134787 TI - [Social and epidemiological aspects in epilepsy. A study of a population of a city of south-low-saxony (author's transl)]. PMID- 4134788 TI - [A contribution to the penicillin therapy of neurosyphilis pharmacokinetic aspects (author's transl)]. PMID- 4134789 TI - [Documentation of laboratory data in neurology with a combined non-computerized and optical mark reader form (author's transl)]. PMID- 4134790 TI - [Myotonic dystrophy associated with periphal neuropathy. Report of the clinical findings in ten cases with concurrent increase of protein levels in CSF (author's transl)]. PMID- 4134791 TI - Luteinizing hormone release and ovulation in anestrous ewes. PMID- 4134792 TI - Pattern of luteinizing hormone release in progestin-treated ewes. PMID- 4134793 TI - Virological investigations of Herpesvirus saimiri-infected owl monkeys. PMID- 4134794 TI - Morphology of mesothelial cells in peritoneal fluid from normal women. PMID- 4134795 TI - Identification of graft and host cells in bone marrow transplants by the quinacrine banding technique of chromosome identification. PMID- 4134796 TI - Value of increased ESR in cold as a test of autoimmunity and its comparison with standard tests. PMID- 4134797 TI - Electron microscopical and cultural features of Neisseria meningitidis competence variants. PMID- 4134798 TI - Purification and characterization of serologically active cell wall substances from Planococcus strains. PMID- 4134799 TI - Invited review. Thalassemia: an abnormality in globin chain synthesis. PMID- 4134800 TI - Experimental infection of Strongyloides westeri in parasite-free ponies. PMID- 4134801 TI - Retinoblastoma with necrosis of central retinal artery and vein and partial spontaneous regression. PMID- 4134802 TI - [Modes of therapeutic management of "early summer meningoencephalitis" (author's transl)]. PMID- 4134803 TI - [REM-syndrome Reticular Erythematous Mucinosis (round-cell erythematosis)]. PMID- 4134804 TI - Canine ceroid-lipofuscinosis-a model for human neuronal ceroid-lipofuscinosis and aging. PMID- 4134805 TI - Myeloma producing nonsecretory IgM and secretory IgG. PMID- 4134806 TI - S-adenosylmethionine: protein-carboxyl methyltransferase from erythrocyte. PMID- 4134807 TI - [Treatment and prevention of recurrences in papillomatosis cutis carcinoides Gottron using bleomycin]. PMID- 4134808 TI - [Diagnosis of monocytic leukemia]. PMID- 4134810 TI - An exclusive right thoracic approach for cancer of the middle third of the esophagus. PMID- 4134811 TI - Adenoid cystic carcinoma of the trachea. Experience with 16 patients managed by tracheal resection. PMID- 4134812 TI - Letter: Cerebrospinal-fluid electrophoresis in SSPE. PMID- 4134809 TI - Immunology of dermatophytes and dermatophytosis. PMID- 4134813 TI - The preferential invasion of young erythrocytes in acute Babesia bigemina infections of splenectomised calves. PMID- 4134814 TI - The fine structure of the microconidium of Blastomyces dermatitidis. PMID- 4134815 TI - Middle ear disease in children. Pathogenesis, diagnosis, and management. PMID- 4134816 TI - An unusual histological cataract. PMID- 4134817 TI - Chemical pathology of multiple sclerosis. PMID- 4134818 TI - Studies on pathogenesis of cervical spondylotic myelopathy: sagittal diameter of the spinal canal and cerebrospinal fluid characteristics in cervical spondylosis. PMID- 4134819 TI - [Artificial insemination in turkeys and an investigation into a suitable diluent of turkey semen (author's transl)]. PMID- 4134820 TI - [Canine glomerulonephrosis. I. Morphology of the lesions (author's transl)]. PMID- 4134821 TI - [Treatment of rheumatoid arthritis with gold. A double-blind study]. PMID- 4134822 TI - Common antigenic structures of HL-A antigens. V. An antigenic determinant characteristic of a 33,000-dalton fragment of HL-A molecules. PMID- 4134823 TI - HL-A antigens on circulating platelets. Ultrastructural demonstration. PMID- 4134824 TI - Hepatic lipid in Reye's syndrome: histochemical and ultrastructural characteristics. PMID- 4134825 TI - [Treatment of disturbances of cardiac rhythm using intravenous disopyramide]. PMID- 4134826 TI - Human dermatophilosis, its occurrence in Brazil. PMID- 4134828 TI - [Complex therapy of occupational allergic dermatoses with pyrogenal and histaglobin]. PMID- 4134827 TI - [Unusual symptomatology of Hodgkin's disease: massive invasion of the blood by abnormal cells]. PMID- 4134829 TI - Interpretation of synovial fluid findings in the horse. PMID- 4134830 TI - [Scleredema adultorum and multiple myeloma (author's transl)]. PMID- 4134831 TI - Cytochemistry of acid mucosubstance and acid phosphatase in Cryptococcus neoformans. PMID- 4134832 TI - The negative staining of "difficult" bacteria like Arthrobacter globiformis for electron microscopy. PMID- 4134833 TI - [Study of the polyribosomes of the spleen of animals immunized with E. coli beta galactosidase]. PMID- 4134834 TI - Biochemical studies on gramicidin S non-producing mutants of Bacillus brevis ATCC 9999. PMID- 4134835 TI - Polarization of the 515 nm effect on chloroplasts oriented by a magnetic field. PMID- 4134837 TI - Prolonged survival in a patient with hepatic malignant melanoma treated by intra arterial bleomycin and oral hydroxyurea. PMID- 4134836 TI - Triiodothyronine and thyroxine in hyperthyroidism. Comparison of the acute changes during therapy with antithyroid agents. AB - In 66 untreated patients with hyperthyroidism, serum triiodothyronine (T(3)) and thyroxine (T(4)) concentrations were measured by immunoassay. The mean T(3) level was 478+/-28 ng/100 ml (all values mean+/-SEM) and the T(4) was 20.6+/-0.6 mug/100 ml. The serum T(4)/T(3) ratio by weight was 48+/-2 as opposed to a value of 71+/-3 in euthyroid adults. There was a significant inverse correlation of the T(4)/T(3) ratios with serum T(3) (r=0.77; P<0.01) but not with serum T(4)(r=0.21). These results suggested that relative overproduction of T(3) is consistently present in patients with hyperthyroidism. To examine the acute effects of various antithyroid agents on serum T(3) and T(4) concentrations, iodide, propylthiouracil (PTU), and methylmercaptoimidazole (MMI) were given alone to mine patients, and serial T(3) and T(4) measurements were made. There was an acute decrease in serum T(3) over the first 5 days in the three iodide and three PTU-treated patients which was greater than that seen in the MMI group. This suggested that PTU and MMI had different effects on T(3) production. To compare the effects of PTU and MMI under conditions in which thyroidal hormone release was minimized, these drugs were given in combination with iodide. The mean daily dosage of PTU was 827 (n=11) and of MMI was 88 (n=8). In the PTU+iodide group, the initial serum T(3) concentration was 586+/-61 ng/100 ml and decreased significantly to 326+/-41 on day 1 and to 248+/-21 on days 2 and 3, respectively, and did not change further on days 4 and 5. In the MMI + iodide group, basal serum T(3) was 645+/-90 ng/100 ml and decreased to 568+/-81, 452+/ 73, and 344+/-51 on days 1, 2, and 3, respectively, and did not change thereafter. While the initial T(3) concentrations in serum were not different in the PTU and MMI groups, the T(3) concentrations in the PTU patients were significantly lower on days 1 and 2 and during the apparent plateau period on days 3-5. Serum T(4) concentrations decreased gradually in both groups, from 23.9+/-2.0 mug/100 ml, initially, to 17.5+/-1.6 on day 5 in the PTU group and from 22.0+/-2.6 to 14.6+/-2.0 in the MMI-treated patients. The T(4) values were not significantly different at any time. These changes resulted in increases in the serum T(4)/T(3) ratios in both groups, but these ratios were substantially higher in the patients treated with PTU + iodide. The initial serum T(4)/T(3) ratio was 43+/-3 and increased to 74+/-7 and 88+/-7 on days 1 and 2 in the PTU group, reaching a plateau value of 91+/-7 during days 3-5. Comparable values for MMI-treated patients were 35+/-2, 42+/-3, 52+/-6, and 54+/-3 during the plateau period. Previous investigations have shown that PTU inhibits T(4) deiodination in hyperthyroid patients and decreases T(3) production from T(4) in animals. The greater acute decrease in serum T(3) and the higher serum T(4)/T(3) ratios in the PTU-treated patients seems best explained by an inhibition of peripheral T(3) production by this agent. This conclusion is further supported by a direct relationship between the T(4)/T(3) ratio on days 3-5 and the dose of PTU administered. These results further suggest that both thyroidal and extrathyroidal pathways contribute substantially to the apparent overproduction of T(3) in hyperthyroidism. PMID- 4134838 TI - [Enuresis--a question of hereditary disposition? (author's transl)]. PMID- 4134839 TI - An analysis of the break points of structural rearrangements in man. PMID- 4134840 TI - Partial trisomy 11 in a child resulting from a complex maternal rearrangement of chromosomes 11, 12 and 13. PMID- 4134841 TI - Cross-reactions between human and animal plasma proteins. V. The role of the antiserum and immunological specificity in relation to the phenomenon of cross reaction. PMID- 4134843 TI - Unusual chromosome bands revealed by aging. PMID- 4134842 TI - Frequency and genetic effect of 1qh plus. PMID- 4134844 TI - Beta-2-microglobulin. Part of the HL-A molecule in the cell membrane. PMID- 4134845 TI - The relation between the "Alte Wiener Schule" and the Spanish medicine of the Enlightenment. PMID- 4134846 TI - Michael Scot and Mary of Bologna: an addendum. PMID- 4134847 TI - Accessory sex glands and their secretions in male Periplaneta americana (L.). II. Secretory behaviour and maturation of the mushroom gland complex. PMID- 4134848 TI - [What significance for the etiology and pathogenesis of rheumatoid arthritis have: d) humoral immune processes]. PMID- 4134849 TI - [What significance for the etiology and pathogenesis of rheumatoid arthritis have: e) cellular immune reaction]. PMID- 4134850 TI - [Scintigraphy of the joints by technetisum 99m]. PMID- 4134851 TI - [Bone changes in chronic inflammatory rheumatic diseases (arthritis, spondylitis) from the clinico-radiologic point of view]. PMID- 4134852 TI - [Unintentional symbolsim in the works of an amateur artist suffering from a chronic depression syndrome]. PMID- 4134853 TI - Gynecomastia in association with administration of thiacetazone in the treatment of tuberculosis. PMID- 4134854 TI - Serum alpha fetoprotein in childhood. PMID- 4134855 TI - Differentiation between early and late membrane antigen on human lymphoblastoid cell lines infected with Epstein-Barr virus. II. Immunoelectron microscopy. PMID- 4134856 TI - Biochemical and morphologic evidence for the presence of an RNA tumor virus in pulmonary carcinoma of sheep (Jaagsiekte). PMID- 4134857 TI - Argentaffin and argyrophil cells in the prostate. PMID- 4134858 TI - Hydralazine-induced Lupoid syndrome. Biochemical and immunological studies. PMID- 4134859 TI - Long-term exposure to auto exhaust and other pollutant mixtures: effects on pulmonary function in the beagle. PMID- 4134860 TI - Natural history of Ebstein's anomaly of tricuspid valve in childhood and adolescence. An international co-operative study of 505 cases. PMID- 4134861 TI - Pseudo AV block produced by concealed extrasystoles arising below the bifurcation of the His bundle. PMID- 4134862 TI - Maintenance of human tumours and tissues in immunosuppressed mice. PMID- 4134863 TI - Elastic tissue in uterine blood vessels. PMID- 4134864 TI - Inhibitory effect of foetal alpha 2 globulin, an acute phase protein, on carrageenin oedema in the rat. PMID- 4134866 TI - Center for Barr body condensation on the proximal part of the human Xq: a hypothesis. PMID- 4134865 TI - Differential spiralization along mammalian mitotic chromosomes. II. 5 bromodeoxyuridine and 5-bromodeoxycytidine-revealed differentiation in human chromosomes. PMID- 4134867 TI - Localization of rDNA in the chromosome complement of the rhesus (Macaca mulatta). PMID- 4134868 TI - Variable satellite DNA's in the African green monkey Cercopithecus aethiops. PMID- 4134869 TI - B-chromosomes in the myrmicine ant, Leptothorax spinosior. PMID- 4134870 TI - Descending connections from the mesencephalon to the inferior olive: an experimental study in the cat. PMID- 4134871 TI - Demonstration by degeneration silver method of the ascending projection from the locus ceruleus. PMID- 4134872 TI - Immunological heterogeneity of Clostridium botulinum type B toxins. PMID- 4134873 TI - Studies on the lethal action of toxotoxin. PMID- 4134874 TI - The medium is as important as the message. PMID- 4134875 TI - Unscramble your word power: learning aid for medical terminology. PMID- 4134876 TI - [Method for combined staining of cellular and tissue structures in histological sections of osseous and cartilaginous tissue]. PMID- 4134877 TI - [Treatment and pathogenesis of ligneous conjunctivitis (author's transl)]. PMID- 4134878 TI - Endogenous rat C-type virus in transplantable rat tumors. PMID- 4134879 TI - [Audio-visual aids in the School of Dentistry of the University of the Andes]. PMID- 4134880 TI - [Preferential efficicacy of immunocomplexes in the facilitation of tumor allografts]. PMID- 4134881 TI - Fine structural topochemistry of entamoeba histolytica Schaudinn, 1903. PMID- 4134882 TI - dsDNA made by RNase-sensitive DNA polymerase from RSV-transformed cells. PMID- 4134883 TI - Surface H-2 antigen concentration requirement of somatic hybrid cells for IgM mediated cytotoxicity. PMID- 4134884 TI - Subunit structure of HL-A antigens on cell surface. PMID- 4134885 TI - Identification of chromosomal abnormalities by quinacrine-staining technique in patients with normal karyotypes by conventional analysis. PMID- 4134886 TI - Letter: Nonketotic hyperosmolar diabetic coma in an infant. PMID- 4134887 TI - Metabolism of albumin and body fluid compartments in protein deficiency--an experimental study in the rhesus monkey. PMID- 4134888 TI - Letter: Gammaglobulin and congenital rubella. PMID- 4134889 TI - Some ultrastructural observations of haematoxyphil vascular change in oat-cell carcinoma. PMID- 4134890 TI - [Immunosuppression of severe dermatomyositis with cytostatic drugs and thymectomy (author's transl)]. PMID- 4134891 TI - [Letter: Examination of thyroid function]. PMID- 4134892 TI - Regional approach to poison control. PMID- 4134893 TI - [Species specific antigen of the causative agent of ornithosis]. PMID- 4134894 TI - The cytochemical bioassay of corticotrophin. PMID- 4134895 TI - Differential DNA synthesis in homologous regions of hybrid polytenic chromosomes (Anopheles atroparvus x A. labranchiae). PMID- 4134896 TI - A phylogenetic study of bird karyotypes. PMID- 4134897 TI - Blood groups of chimpanzees. PMID- 4134898 TI - Letter: Scabies in babies. PMID- 4134899 TI - Nitrogenase. PMID- 4134900 TI - Banding and chromatid separation in Chinese hamster chromosomes. PMID- 4134901 TI - Letter: Spotted centromeres in human chromosomes. PMID- 4134902 TI - Hyperthyroidism associated with pregnancy. PMID- 4134903 TI - A staining method for keratohyalin granules. PMID- 4134904 TI - Proceedings: Search for a viral etiology of human breast cancer. PMID- 4134905 TI - The sialic acid content in mouse female reproductive organs as a quantitative parameter for testing the estrogenic and antiestrogenic effect, antiestrogenic depot effect, and dissociated effect of estrogens on the uterus and vagina. PMID- 4134906 TI - Primary lipoidal degeneration of the cornea. PMID- 4134907 TI - Choriocarcinoma of the testis. PMID- 4134908 TI - Argyrophil cells and melanocytes in esophageal mucosa. PMID- 4134909 TI - Pulmonary fat embolism. An ultrastructural study. PMID- 4134910 TI - Muscle regeneration in the dystrophic Syrian hamster tongue. Effects of a moderately severe crushing injury. PMID- 4134911 TI - [Polyploidization of grain species by lindane insecticides]. PMID- 4134912 TI - [Comparative topic treatments of basal cell carcinomas and senile keratoses with 5-FU, retinoic acid and DNCB sensitization (author's transl)]. PMID- 4134913 TI - Induction of C-type particles in mammalian cancer cells. PMID- 4134914 TI - RNA directed DNA polymerase in C-type particles form normal rat thymus cultures and Moloney leukemia virus. PMID- 4134915 TI - Letter: Angio-immunoblastic lymphadenopathy with dysproteinaemia. PMID- 4134916 TI - Inequality and the health service. PMID- 4134917 TI - Clinical evaluation of the turkey-erythrocyte passive-haemagglutination test for hepatitis-B surface antigen. PMID- 4134918 TI - Drug-associated diarrhoea as a potential reservoir for hospital infections. PMID- 4134919 TI - Editorial: Tobacco smoke and the non-smoker. PMID- 4134920 TI - Psychiatric illness in doctors. PMID- 4134922 TI - Letter: Double failure of technically correct laparoscopic sterilization. PMID- 4134921 TI - Letter: Typhoid fever treated with chloramphenicol and co-trimoxazole. PMID- 4134923 TI - Letter: A new leg-prosthesis socket. PMID- 4134924 TI - Letter: Intravenous metronidazole in amoebic liver abscess. PMID- 4134925 TI - Letter: Post-pill fertility. PMID- 4134926 TI - Letter: Ankylosing spondylitis, sacroiliitis, regional enteritis, and HL-A 27. PMID- 4134927 TI - Tentative method of analysis for polynuclear aromatic hydrocarbons in automobile exhaust. PMID- 4134928 TI - Morphology of bacteriophage-like particles from Fusobacterium symbiosum. AB - The morphology of bacteriophage-like particles from the strict anaerobe Fusobacterium symbiosum is described. Attempts to demonstrate plaque formation on the host strain of F. symbiosum and other related species were unsuccessful. PMID- 4134930 TI - [Letter: Index of prematurity in ECG]. PMID- 4134929 TI - Beat-by-beat stroke volume from aortic-pulse-pressure analysis. PMID- 4134931 TI - A simple method for R banding of human chromosomes, showing a pH-dependent connection between R and G bands. PMID- 4134932 TI - [Ultrastructure of the nerve cells intravitally stained by neutral red]. PMID- 4134933 TI - [Formation and fixation of spherical structures in nucleated frog erythrocytes incubated in solutions of basic dyes and alkaloids (observation of single cells)]. PMID- 4134934 TI - [Immunoendocrinology]. PMID- 4134935 TI - Bacterial plaque disclosure survey. PMID- 4134936 TI - Salbutamol by intermittent positive pressure ventilation in status asthmaticus. PMID- 4134937 TI - [Histochemical investigations of metabolic activity of chloragosomes of Lumbricus terristris]. PMID- 4134938 TI - Studies on the cephalochordates of the Madras coast. 15. The nature of the structural polysaccharide in amphioxus, Branchiostoma lanceolatum. PMID- 4134939 TI - Cytochemical study of non-specific esterase, acid and alkaline phosphatase in the human thyroid neoplasms. PMID- 4134940 TI - Histochemical study on the oxidative enzymes of the interstitial cells of the renal medulla in rats. PMID- 4134941 TI - Histochemical analysis of thermal effects on the high pH metachromasia of galactogen. PMID- 4134942 TI - [Adsorption of horseradish peroxidase to ruthenium-red-positive structures in myeli-free nerves]. PMID- 4134943 TI - Basic nuclear proteins in a coelenterate; a cytochemical demonstration of histones in Hydra. PMID- 4134944 TI - Some enzyme histochemical studies of the transitional epithelium of mammalian urinary tract. PMID- 4134945 TI - [Quantitative histochemical demonstration of sulfhydrylgroups by the DDD-staining method. II. Determination of the SH-groups in insoluble proteins (author's transl)]. PMID- 4134946 TI - Histochemical aspects of hydatidiform mole and choriocarcinoma. PMID- 4134947 TI - Chemical nature of the hooks of the cystacanth of Moniliformis moniliformis. PMID- 4134948 TI - [Absorption of the anionic phthalocyanine dye Heliogen Blue K by single muscle fibers]. PMID- 4134949 TI - [Thoughts on urinary lithiasis among adults in Senegal]. PMID- 4134950 TI - [Species determination of dried blood by the method of immunofluorescence]. PMID- 4134951 TI - Regulation of hepatic transketolase activity by thiamin. PMID- 4134952 TI - Are patients satisfied? PMID- 4134954 TI - Evaluation of a prospective dental student. PMID- 4134953 TI - Dental school application is a disgrace. PMID- 4134955 TI - On becoming a professional. PMID- 4134956 TI - What is a professional? PMID- 4134957 TI - [Prolongation of allograft survival in mice by transplantation antigens incubated with normal serum. 1. Identification of the active serum fraction]. PMID- 4134958 TI - Is prolactin involved in precipitating migraine? PMID- 4134959 TI - Brain-decarboxylase activities as indices of pathological change in senile dementia. PMID- 4134960 TI - Is an acute disturbance in hepatic transport of bile-acids the primary cause of cholestasis in benign recurrent intrahepatic cholestasis? PMID- 4134961 TI - Spread of meningococcal infection within households. PMID- 4134962 TI - Letter: Nephritis after irradiation and chemotherapy for nephroblastoma. PMID- 4134963 TI - Letter: Effect of baclofen on myotonia. PMID- 4134964 TI - Recurrent meningococcal infection with an antigenically identical strain. PMID- 4134965 TI - Humoral response in patients with liver disease. PMID- 4134967 TI - [Prevention of infections during travel abroad]. PMID- 4134966 TI - Detection of protein subunits of ferritin in situ in cells by immunofluorescence. AB - Antisera raised in rabbits against protein subunits of rat liver ferritin contain antibodies (IgG) that precipitate subunits and other antibodies (IgG) that precipitate undissociated ferritin and apoferritin. Removal of the latter antibodies from IgG fractions of immune sera by repeated addition of ferritin leaves antibodies that specifically precipitate subunits. Using these subunit specific antibodies, we have demonstrated the presence of subunit-positive sites in cells by immunofluorescence. Subunit-positive sites were best demonstrated in rats that had been loaded with iron. These sites were diffusely spread through the cytoplasm of hepatocytes and Kupffer cells in rat livers and of macrophages and fibroblasts in rat livers and hearts. With antibodies to ferritin, the presence of ferritin was demonstrated in the same kinds of cells. Although, by immunofluorescence, the intracellular localization of ferritin-positive and subunit-positive sites was similar, ferritin-positive immunofluorescence was most intense in Prussian blue-positive cytoplasmic granules in which high concentrations of ferritin were presumed to be present on the basis of electron microscopic studies. Our findings can be interpreted to indicate either the presence of unassociated subunits or of fragments of subunits in the cytoplasm of the several kinds of cells studied. It is also possible that partly assembled molecules of ferritin or apoferritin in these cells reacted with subunit-specific antibodies. Subunit-specific antibodies may be useful for localizing sites of assembly of ferritin molecules at the level of cell fine structure and for elucidation of the biosynthesis of ferritin. PMID- 4134968 TI - Modified two-dimensional polyacrylamide gel electrophoresis systems for higher molecular weight nonhistone chromatin proteins from normal rat liver and Novikoff hepatoma ascites cells. PMID- 4134969 TI - Loss of DNA following C-banding procedures. PMID- 4134970 TI - Localization of sister chromatid exchanges in human chromosomes. AB - The bromodeoxyuridine; sensitivity of 33258 Hoechst fluorescence allows microfluorometric analysis of sister chromatid exchanges in human metaphase chromosomes. The frequency of sister chromatid exchanges among chromosomes correlates with chromosome length. Exchanges appear to occur predominantly in interband regions, as defined by quinacrine fluorescence, or very near band interband junctions. A few regions are involved unusually frequently. PMID- 4134972 TI - Letter: Lactic acidosis and hyperlactataemia. PMID- 4134971 TI - [Morphology of tissue forms of pathogenic organisms in vesceral mycoses. Studies on the histochemistry of polysaccharides and proteins. 4. Coccidioides immitis]. PMID- 4134973 TI - Editorial: Screening for hepatitis B. PMID- 4134974 TI - Directionality of brain microtubule assembly in vitro. AB - Chicks were injected intra-cerebrally with [(3)H]leucine, and (3)H-labeled microtubules were assembled in vitro in the brain supernatants. Pieces of these (3)H-labeled microtubules were then incubated with unlabeled brain tubulin subunits under conditions where the subunits assembled onto the labeled pieces. Electron microscopic autoradiography of the negatively-stained microtubules showed all of the radioactivity at one end of the tubules as they increased in length. This clearly demonstrated that the microtubules of brain in this in vitro system were being assembled unidirectionally. PMID- 4134975 TI - Regulatory processes of DNA synthesis in the embryo. PMID- 4134976 TI - Detection of areas of wall differentiation in fungi using fluorescent staining. PMID- 4134977 TI - [Sialic acids on the surface of plasmic membranes of cells originating in human lymphoid lines]. PMID- 4134978 TI - [Characteristic changes in the myofilaments and discus intercalaris of the myocardium following isoproterenol administration in rats]. PMID- 4134979 TI - [Free and total histamine levels in postmortem burns in rats]. PMID- 4134980 TI - [Embryologic study of the intraepithelial section of the eccrine sweat gland]. PMID- 4134981 TI - Response in macromolecular syntheses of mouse L cells to bleomycin, with special reference to cell-antibiotic interaction. PMID- 4134982 TI - [New data on the pathogenesis of gastric ulcer]. PMID- 4134984 TI - [A modern refresher method: posters]. PMID- 4134983 TI - [Cancers of the main bile duct. Diagnostic and therapeutic problems related to 20 cases]. PMID- 4134985 TI - Isolation of mammalian heterochromatin and euchromatin. PMID- 4134986 TI - Measurements of mammalian cellular DNA and its localization in chromosomes. PMID- 4134987 TI - Quantitative light microscopic autoradiography. PMID- 4134988 TI - Methods in the cellular and molecular biology of paramecium. PMID- 4134989 TI - Effect of bleomycin on the chromosomes of human lymphocytes at various cell phases. PMID- 4134990 TI - Enhancing effect of clamping of the portal vein on the effectiveness of antitumor agents against abdominal tumor growth. PMID- 4134991 TI - Isolation of hepatocytic mitosis-inhibiting protein from normal rat plasma. PMID- 4134992 TI - Sex-hormone-binding globulin. PMID- 4134993 TI - Interaction of ruthenium red with isolated sarcolemma. PMID- 4134994 TI - [Effect of vitamin B 12 on the serum proteins and protein fractions in chick embryos]. PMID- 4134995 TI - Cyclical phenomena in persistent virus infection. PMID- 4134996 TI - Long-term serial cell cultivation of human brain tumor in vitro. PMID- 4134997 TI - [Study of some physicochemical properties and the antigenic specificity of the hexone of adenovirus type I]. PMID- 4134998 TI - [Group-specific cellular antigens in the composition of parainfluenza viruses]. PMID- 4134999 TI - Relationship of uptake of sodium and 45calcium to ATP-induced histamine release from rat mast cells. PMID- 4135000 TI - Aetiology of multiple sclerosis. PMID- 4135002 TI - Demonstration of a fibrillar component in the cell wall of the yeast Saccharomyces cerevisiae and its chemical nature. AB - The ultrastructure of isolated cell walls of Saccharomyces cerevisiae from the log and stationary phases of growth was studied after treatment with the following enzymes: purified endo-beta-(1 --> 3)-glucanase and endo-beta-(1 --> 6) glucanase produced by Bacillus circulans; purified exo-beta-glucanase and endo beta-(1 --> 3)-glucanase produced by Schizosaccharomyces versatilis; commercial Pronase. While exo-beta-glucanase from S. versatilis had no electron microscopically detectable effect on the walls, Pronase removed part of the external amorphous wall material disclosing an amorphous wall layer in which fibrils were indistinctly visible. Amorphous wall material was completely removed by the effect of either endo-beta-(1 --> 3)- or endo-beta-(1 --> 6)-glucanase of B. circulans or by a mixture of the two enzymes. As a result of these treatments a continuous fibrillar component appeared, composed of densely interwoven microfibrils resisting further action by both of the B. circulans enzymes. The fibrillar wall component was also demonstrated in untreated cell walls by electron microscopy after negative staining. Because of the complete disappearance of the fibrils following treatment with the S. versatilis endo-beta (1 --> 3)-glucanase it can be concluded that this fibrillar component is composed of beta-(1 --> 3)-linked glucan. Bud scars were the only wall structures resistant to the effect of the latter enzyme. PMID- 4135001 TI - Assembly of gap junctions during amphibian neurulation. AB - Sequential thin-section, tracer (K-pyroantimonate, lanthanum, ruthenium red, and horseradish peroxidase), and freeze-fracture studies were conducted on embryos and larvae of Rana pipiens to determine the steps involved in gap junction assembly during neurulation. The zonulae occludentes, which join contiguous neuroepithelial cells, fragment into solitary domains as the neural groove deepens. These plaque-like contacts also become permeable to a variety of tracers at this juncture. Where the ridges of these domains intersect, numerous 85-A participles apparently pile up against tight junctional remnants, creating arrays recognizable as gap junctions. With neural fold closure, the remaining tight junctional elements disappear and are replaced by macular gap junctions. Well below the junctional complex, gap junctions form independent of any visible, preexisting structure. Small, variegated clusters, containing 4-30 particles located in flat, particle-free regions, characterize this area. The number of particles within these arrays increases and they subsequently blend together into a polygonally packed aggregate resembling a gap junction. The assembly process in both apical and basal regions conforms with the concept of translational movement of particles within a fluid plasma membrane. PMID- 4135003 TI - Prophasing of interphase nuclei and induction of nuclear envelopes around metaphase chromosomes in HeLa and Chinese hamster homo- and heterokaryons. AB - Fusing human HeLa metaphase cells with HeLa interphase cells resulted within 30 min in either of two phenomena in the resultant binucleate cell: either prophasing of the interphase nucleus or formation of a normal-appearing nuclear envelope around the metaphase chromosomes. The frequency of either occurrence was strongly dependent on environmental pH. At pH's of 6.6-8.0, prophasing predominated; at pH 8.5 nuclear envelope formation predominated. Additionally, the frequencies of the two events in multinucleate cells depended on the metaphase/interphase ratio. When the ratio was 0.33 nuclear envelope formation predominated; when it was 2.0 prophasing predominated. In their general features, the results with fused HeLa cells resembled those reported earlier with fused Chinese hamster Don cells. However, the results provided an indication that between pH 6.6 and 8.0 the HeLa metaphase cells possessed a much greater capacity than the Don metaphase cells to induce prophasing. Fusion of Don metaphase cells with HeLa interphase cells or of Don interphase cells with HeLa metaphase cells at pH 8.0 resulted in nuclear envelope formation or prophasing in each kind of heterokaryon. As in the homokaryons, the frequencies of the two events in the heterokaryons depended on the metaphase/interphase ratio. The statistics of prophasing and nuclear envelope formation in the homo- and heterokaryon populations were consistent with the notion that disruption or formation of the nuclear envelope depends on the balance attained between disruptive and formative processes. PMID- 4135004 TI - Autoradiographic studies of synthesis and intracellular migration of glycoproteins in the rat anterior pituitary gland. AB - The incorporation of [(3)H]fucose in the somatotrophic and gonadotrophic cells of the rat adenohypophysis has been studied by electron microscope autoradiography to determine the site of synthesis of glycoproteins and to follow the migration of newly synthesized glycoproteins. The pituitaries were fixed 5 min, 20 min, 1 h, and 4 h after the in vivo injection of [(3)H]fucose and autoradiographs analyzed quantitatively. At 5 min after [(3)H]fucose administration, 80-90% of the silver grains were localized over the Golgi apparatus in both somatotrophs and gonadotrophs. By 20 min, the Golgi apparatus was still labeled and some radioactivity appeared over granules. At 1 h and 4 h, silver grains were found predominantly over secretory granules. The kinetic analysis showed that in both protein-secreting cells (somatotrophs) and glycoprotein-secreting cells (gonadotrophs), the glycoproteins have their synthesis completed in the Golgi apparatus and migrate subsequently to the secretory granules. It is concluded from these in vivo studies that glycoproteins which are not hormones are utilized for the formation of the matrix and/or of the membrane of the secretory granules. The incorporation of [(3)H]fucose in gonadectomy cells (hyperstimulated gonadotrophs) was also studied in vitro after pulse labeling of pituitary fragments in medium containing [(3)H]fucose. The incorporation of [(3)H]fucose was localized in both the rough endoplasmic reticulum (ER) and the Golgi apparatus. Later, the radioactivity over granules increased while that over the Golgi apparatus decreased. The concentration of silver grains over the dilated cisternae of the rough ER was not found to be modified at the longest time intervals studied. PMID- 4135005 TI - Intracellular binding of ruthenium red in frog skeletal muscle. PMID- 4135006 TI - Peptide and amine producing endocrine-like cells in the chicken thymus. A chemical, histochemical and electron microscopic study. PMID- 4135007 TI - Studies on 5'-nucleotidase histochemistry. I. 5'-Nucleotidase activity in the developing esophagus of the mouse. PMID- 4135008 TI - Some effects of salts on staining: use of the Donnan equilibrium to describe staining of tissue sections with acid and basic dyes. PMID- 4135009 TI - Thiosulphation for the histochemical demonstration of protein-bound sulphydryl and disulphide groups. PMID- 4135010 TI - Electron microscopy and diffraction of wet unstained and unfixed biological objects. PMID- 4135011 TI - Renal glycoprotein: glycosyl transferase activities after administration of folic acid. PMID- 4135012 TI - The deposition of dental plaque in young adults on a diet containing chocolate and skim-milk powder. PMID- 4135013 TI - Alpha-fetoprotein levels in amniotic fluid in pregnancies complicated by rhesus isoimmunization. PMID- 4135014 TI - Formamidase in rat brain. PMID- 4135016 TI - Psychotic "art" in New Guinea. A cross-cultural study. PMID- 4135015 TI - Diamorphine-induced attack of paroxysmal hypertension in phaeochromocytoma. PMID- 4135017 TI - The recovery cycle of the averaged auditory evoked response during sleep in normal children. PMID- 4135018 TI - Cerebellar responses to penicillin-induced cerebral cortical epileptiform discharge. PMID- 4135019 TI - Intra-hemispheric phase relationships during self-regulated alpha activity. PMID- 4135020 TI - Age and sex differences in averaged evoked responses in a normal population, with observations on patients with gonadal dysgenesis. PMID- 4135021 TI - Contamination of scalp EEG spectrum during contraction of cranio-facial muscles. PMID- 4135022 TI - An implantable multi-channel biotelemetry system. PMID- 4135023 TI - [Differential effects of p-chlorophenylalanine on sleep in primates, Papio papio and Papio hamadryas]. PMID- 4135024 TI - Alpha wave phase and alpha attenuation. PMID- 4135025 TI - The recovery cycle of the averaged auditory evoked response during sleep in autistic children. PMID- 4135026 TI - [Procedure for discrimination between simple and complex Purkinje cell unitary discharges]. PMID- 4135027 TI - An electrode for recording single motor unit activity during strong muscle contractions. PMID- 4135028 TI - A simple eye movement monitoring system for clinical electroencephalography. PMID- 4135029 TI - A dual digital integrator for EEG studies. PMID- 4135030 TI - A technique for feature extraction and interpatient comparison of H-reflex conditioning curves. PMID- 4135031 TI - An electronic device for continuous counting of chemically induced epileptic discharges. PMID- 4135032 TI - Escherichia coli antibody: a screening test for immunodeficiency. AB - Six patients suffering from recurrent chest infections were found to lack antibodies to a pooled antigen obtained from six different serotypes of commensal Escherichia coli bacteria. All had normal serum IgG concentrations, but five subsequently benefited from regular gammaglobulin injections. We suggest that the absence of such E. coli antibodies usually indicates a clinically significant defect in antibody production. This simple screening test is of use in the diagnosis of primary and secondary immunodeficiency disorders. PMID- 4135033 TI - Fractionation and purification of prostatic acid phosphatase. PMID- 4135034 TI - Androgen assimilation by normal and hyperplastic dog prostate glands. PMID- 4135036 TI - Preventive dentistry: fads and facts. PMID- 4135035 TI - [The audio-visual continuing education program of the F.D.A]. PMID- 4135038 TI - Gilbert Frewin Hamilton. PMID- 4135037 TI - Homologous radioimmunoassay of thyrotrophin in rat plasma. PMID- 4135039 TI - Immunology of the tears. PMID- 4135040 TI - [Current problems in the pathogenesis and therapy of acute inflammation]. PMID- 4135041 TI - Regional variation in the permeability of rat thoracic aorta. AB - The permeability and ultrastructure of the intercostal orifices and interostial regions of rat thoracic aorta have been compared in the present study. The ostial regions consist of two different portions, an annulus and an inflow tract, the latter being continuous with the intercostal artery. The wall of the inflow tract has a sharp bend, demarcating inner and outer portions. Faint blueing of the lateral portions of aortic annuli is visible from 3(1/2) to 4(1/2) hours after injection of Evans blue dye and is no longer apparent at 5(1/2) hours, when there is diffuse discoloration of the thoracic aorta. Only the annuli are labeled by horseradish peroxidase (HRP) for 1(1/2) to 3(1/2) minutes after intravenous injection. There is more extensive and progressively heavier labeling of annuli and inner halves of the inflow tracts between 5 to 12 minutes. HRP is transported across aortic endothelium within micropinocytotic vesicles. Intercellular endothelial clefts do not appear to be directly permeated from the lumen through their junctions for a period of at least 3(1/2) minutes. The present observations preclude an assessment of the penetration of the junctions by HRP at later intervals. No appreciable differences are observed in the mode of transport of peroxidase through the more permeable endothelium of the annulus and less permeable endothelium of inflow tract and interostial regions. Observations made on tissues exposed to colloidal lanthanum, and on specimens stained en bloc with uranyl acetate and subjected to a combination of rotation-tilting, fail to demonstrate appreciable differences in the ultrastructure of the endothelial cell junctions of intercostal orifices and interostial regions. Since morphologic differences do not seem to account for the greater permeability of annular regions, the role of hemodynamic forces is considered. The relationship between regional variation in permeability and the development of atherosclerotic lesions is also discussed PMID- 4135042 TI - [The action of an oral rhinological agent on the nasal mucous membrane (author's transl)]. PMID- 4135043 TI - Histological and ultrastructural study of the glial pigment in pallidum and striatum of man. PMID- 4135044 TI - [Intrahepatic cholestasis following ovosiston]. PMID- 4135045 TI - [Oral contraceptives as a cause of cerebral circulatory disturbances? (author's transl)]. PMID- 4135046 TI - The fatty acid composition of cerebrosides and sulfatides in a case of adult metachromatic leukodystrophy. PMID- 4135047 TI - Enrichment in B cells after separation of lymphocytes from peripheral blood. PMID- 4135048 TI - Electrophoretic studies on the variations in serum protein profiles of golden hamsters infected experimentally with Opisthorcis felineus (Rivolta, 1884): globulin fractions. PMID- 4135049 TI - [Etiologic and pathogenetic factors of chronic polyarthritis. 3. Synopsis]. PMID- 4135050 TI - The relation of millisecond delayed light emission to light-induced ion accumulations in chloroplasts. PMID- 4135051 TI - Purification of a specific antibody to rat liver malic enzyme by affinity chromatography and application of the antibody as a quantitative reagent. PMID- 4135052 TI - [Study of mitochondrial structure by means of freeze cleavage and etching]. PMID- 4135053 TI - Banding analysis of the chromosomes of Marmosa mitis (murine opossum). PMID- 4135054 TI - Electron microscopic demonstration of rat liver glycogen phosphorylase activity with iron (Fe++). PMID- 4135055 TI - New studies on the neural crest origin of the avian ultimobranchial glandular cells--interspecific combinations and cytochemical characterization of C cells based on the uptake of biogenic amine precursors. PMID- 4135056 TI - [Critical study of tinctorial distribution proposed among endocrine cells of the fundic mucosa in the rabbit (author's transl)]. PMID- 4135057 TI - [Histochemical characterisation of antral epithelial weak green fluorescent cells of the rabbit. Their correspondance with gastrin cells (author's transl)]. PMID- 4135058 TI - A quantitative approach for immunofluorescence in microscopy: the use of antibody multilayers on nuclei. PMID- 4135059 TI - Scanning electron microscopy: identification of mast cells by indirect cathodoluminescence. PMID- 4135062 TI - [Albumin binding of the hepatotropic contrast medium Biligrafin]. PMID- 4135060 TI - Morphological and histochemical observations of the regenerated mucosa of the duodenum of the fowl after sub-total villous atrophy. PMID- 4135061 TI - Glycoprotein: glycosyl transferase activities of rat kidney plasma membranes. PMID- 4135063 TI - Iodine metabolism in leukocytes: effect of graded iodide concentrations. PMID- 4135064 TI - Rapid detection of hypoxanthine-guanine phosphoribosyltransferase on cellogel. PMID- 4135065 TI - [Inherited translocation t(4q minus;18q plus) with unbalanced progeny of different types (author's transl)]. PMID- 4135066 TI - DNA coating of blood vessels in retinoblastomas. PMID- 4135067 TI - [Disorders of speech development in childhood (author's transl)]. PMID- 4135068 TI - Mammalian cytogenetics. 8. Q-banding of chromosomes of Pan troglodytes, Gorilla gorilla berngei and Pongo pygmaeus. PMID- 4135069 TI - [Microscopical studies on the morphology of lympho-induced tumor cell destruction in vitro (author's transl)]. PMID- 4135070 TI - [Lesions of the right heart in carcinoid syndrome. Histochemical and ultrastructural study]. PMID- 4135071 TI - Alpha-chain disease with clinical, immunological, and histological recovery. AB - Clinical, immunological, and histological recovery in a patient with alpha-chain disease is described. The patient, a 27-year-old Greek man, presented with severe steatorrhoea, abdominal pain, oedema, and hypogammaglobulinaemia. Treatment with tetracycline produced only temporary remission. Intermittent therapy with prednisone and cyclophosphamide together with antibiotics was followed by clinical recovery, return of histological appearances of the small intestine to normal, and disappearance of free alpha-chain protein from the serum. The patient remained well one year later without treatment. PMID- 4135072 TI - Follicular lymphoma with deposits of amorphous hyaline material. PMID- 4135073 TI - Heterochromatin distribution and chiasma localization in the grasshopper Btyodema tuberculata (Fabr.) (Acrididae). PMID- 4135074 TI - [Clinical test of oxymetazoline-HCl-nose drops for infants (Nasivin 0,01 per cent)]. PMID- 4135075 TI - Selective staining of cell nuclei with haematoxylin containing transitional metal cations. PMID- 4135076 TI - Turner phenotype: mosaic 45,X-47,XY, plus 18. PMID- 4135077 TI - Autosomal reciprocal translocations in newborn children and their relatives. PMID- 4135078 TI - On the mechanism of T-cell mediated cytolysis. PMID- 4135079 TI - [Lead (author's transl)]. PMID- 4135080 TI - [Density (specific gravity) of microorganic cells]. PMID- 4135081 TI - [Histochemical and ultrastructural study of the secretion from neurosecretory pericaryons of the pars intercerebralis of the wasp Polistes]. PMID- 4135082 TI - [Substantive bindings of tetrazolium salts. Light and electronmicroscopy observations]. PMID- 4135083 TI - [Microscopic and ultramicroscopic studies of the skeletal muscle in acute and chronic experimental ischemia]. PMID- 4135084 TI - Mucopolysaccharides histochemistry of Musca domestica. IX. The oenocytes. PMID- 4135085 TI - [Immunohistochemical evidence of the change of the number of glucagon producing cells in the islets of Langerhans after truncular vagotomy (author's transl)]. PMID- 4135086 TI - [The histochemical evidence of insulin in the islets of Langerhans after truncular vagotomy (author's transl)]. PMID- 4135087 TI - The hatching process in fish embryos. 3. The structure, polysaccharide and protein cytochemistry of the chorion of the trout egg, Salmo gairdneri (Rich.). PMID- 4135088 TI - Histochemical studies on the mucins of the vertebrate tongues. V. Comparative mucopolysaccharide histochemistry of the mast cells in the tongues of twenty vertebrates. PMID- 4135089 TI - Familial hyperparathyroidism. PMID- 4135090 TI - The quantitative partition of the albumin fraction of milk serum proteins by gel chromatography. PMID- 4135091 TI - Changes of internal elastic membrane in the coronary arteries as related to atherosclerotic involvement. PMID- 4135092 TI - Muscle biopsy--technical and diagnostic aspects. PMID- 4135093 TI - Specificities of antisera against testosterone linked to albumin at different positions (C3, C11, C17). PMID- 4135094 TI - [Transformation of a NH group into a N-OH group (author's transl)]. PMID- 4135095 TI - Current thoughts on management of hyperthyroidism. PMID- 4135096 TI - [In vitro synthesis of alfa fetoprotein by cultures of human liver cancer cells]. PMID- 4135097 TI - Progesterone in the management of hormone-dependent inoperable tumours. PMID- 4135098 TI - [Immunoelectrophoresis in dermatological practice. II. Deficiency proteinemias, Hypogammaglobulinemias]. PMID- 4135099 TI - [Therapy of lupus-nephritis using corticosteroids and immunosuppressive agents]. PMID- 4135100 TI - A comparative study on rat liver and hepatoma nuclear membranes. PMID- 4135101 TI - Loss of small peripheral sensory neurons in Fabry disease. Histologic and morphometric evaluation of cutaneous nerves, spinal ganglia, and posterior columns. PMID- 4135102 TI - Serological properties and amino acid composition of the fimbriae of Aeromonas hydrophila. PMID- 4135103 TI - The ion exchanger character of insoluble collagen fraction isolated from bovine nasal septal cartilage. PMID- 4135104 TI - Sex hormones--effects on prolactin cells. PMID- 4135105 TI - Letter: Identification of two populations of human lymphocytes. PMID- 4135106 TI - The passive cutaneous anaphylaxis test (PCA) in the diagnosis of allergic respiratory diseases caused by hypersensitivity to organic dust. PMID- 4135107 TI - [Diagnosis of peripheral arthropathies (author's transl)]. PMID- 4135108 TI - Biochemical aspects of drug combinations. PMID- 4135109 TI - Carbon monoxide hazard in Cairo traffic. PMID- 4135110 TI - Liver ultrastructure in abetalipoproteinemia: Evolution of micronodular cirrhosis. PMID- 4135111 TI - Editorial: Steatosis-Mallory's hyaline-cirrhosis: Can their relationships be resolved by an experiment of nature? PMID- 4135112 TI - Specificity differentiation of herpes simplex virus types 1 and 2 by indirect immunofluorescence. PMID- 4135113 TI - Influence of the mutation "diabetes" on insulin release and islet morphology in mice of different genetic backgrounds. AB - Mice, 7-8-mo old, of the C57BL/KsJ-db strain and homozygotic for the mutant gene db, exhibited marked hyperglycemia and moderately elevated serum insulin levels. Light and electron microscopy provided evidence of a slightly decreased proportion of beta cells in the pancreatic islets, irregular islet architecture with intraislet ducts, and degenerative as well as hypertrophic changes in the individual beta cells. As a rule, islets microdissected from these mice did not release insulin in response to glucose, theophylline, iodoacetamide, or chloromercuribenzene-p-sulphonic acid. The absence of secretory responses was not simply due to lack of insulin. Although the islet content of insulin was decreased in C57BL/KsJ-db/db mice, the remaining amount was severalfold larger than that released from stimulated islets of normal controls. Another mutation, db(2J), an allele of db with identical phenotypic expressions in the C57BL/KsJ strain, was studied on the genetic background C57BL/6J. In contrast to the severely diabetic C57BL/KsJ-db/db animals, the C57BL/6J-db(2J)/db(2J) mice were characterized by highly elevated serum insulin levels and only moderate hyperglycemia. Their endocrine pancreas was enlarged and showed an increased proportion of beta cells. Like the islets of normal mice, those of C57BL/6J db(2J)/db(2J) mice responded to glucose and chloromercuribenzene-p-sulphonic acid, the glucose-induced responses being potentiated by theophylline or iodoacetamide. C57BL/KsJ-db/db mice should provide a valuable model for studying defects in insulin secretion in relation to diabetes mellitus. Mice of the C57BL/6J strain offer a control material that may help to elucidate the dependence of the insulin secretory defect on the background genome. PMID- 4135115 TI - Identification of Streptococcus mutans colonies by mannitol-dependent tetrazolium reduction. PMID- 4135114 TI - Fluorescamine: a novel reagent for the histochemical detection of amino groups. PMID- 4135116 TI - Hodgkin's disease 1974. PMID- 4135117 TI - Investigation of a cell strain with trisomy 14 from a spontaneously aborted human fetus. PMID- 4135118 TI - [Perimembrane structures of animal cells (the structural and chemical organization of "thick membranes")]. PMID- 4135119 TI - [Cooperative binding of organic dyes by frog actomyosin]. PMID- 4135120 TI - [Study of the structural changes in the lysosomal membranes to the action of histones]. PMID- 4135121 TI - Avian oral pigmentation. PMID- 4135122 TI - Gingival fluid in relation to tooth mobility and occlusal interferences. PMID- 4135123 TI - [Quantitative histochemical demonstration of sulfhydrylgroups by the DDD-staining method. 3. Quantitative cytospectrometrical determination in Ehrlich-ascites tumour cells (author's transl)]. PMID- 4135124 TI - The identification of adrenergic and cholinergic nerve endings in the trabecular meshwork. PMID- 4135125 TI - The effect of bleomycin and radiation in combination on bacteria and mammalian cells in culture. PMID- 4135126 TI - The distribution of repetitive DNA in the chromosomes of cultured cells of Drosophila melanogaster. PMID- 4135127 TI - End results of breast cancer patients in Finland 1953-1968. PMID- 4135128 TI - Breast milk: a source of more than nutrition for the neonate. PMID- 4135129 TI - Histamine release from mast cells: role of microtubules. PMID- 4135131 TI - Michael Scot and Mary of Bologna. A medieval gynecological puzzle. PMID- 4135130 TI - Significance of postradiation bronchoscopical findings in the prognosis of bronchial carcinoma. PMID- 4135132 TI - Defective translational control in the beta-thalassemia of Ferrara. PMID- 4135133 TI - The DNA content of sperm and hemocyte nuclei of the silkworm, Bombyx mori L. PMID- 4135134 TI - DNA replication and RNA transcription of euchromatic and heterochromatic chromosome regions during grasshopper meiosis. PMID- 4135135 TI - A review of the genus Chironomus (Diptera, Chironomidae). IX. The cytology of Chironomus tepperi Skuse. PMID- 4135136 TI - DNA replication, G- and C-bands and meiotic behaviour of supernumerary chromosomes of Rattus rattus (Linn.). PMID- 4135137 TI - Chromosomal banding patterns and karyotype evolution in three pig kidney cell strains (PK15, F and RP). PMID- 4135138 TI - Euploid segregation through multipolar mitosis in mammalian cell cultures. Identification of triploid, haploid, and segregating diploid cells in a diploid euploid primary culture of rhesus kidney cells. PMID- 4135140 TI - [Flow-through cytophotometric prescreening--a comparison of methods (author's transl)]. PMID- 4135139 TI - Immunological studies on chimpanzee plasma proteins. PMID- 4135141 TI - A monolayer and freeze-etching study of charged phospholipids. I. Effects of ions and pH on the ionic properties of phosphatidylglycerol and lysylphosphatidylglycerol. PMID- 4135142 TI - [Comparative electrophoretic studies of the blood serum in experimental spirochetosis]. PMID- 4135143 TI - [Identification of the parathyroid glands by means of in vivo staining: preliminary experimental results with various clinical observations]. PMID- 4135144 TI - Metastatic basal cell carcinoma: review, report of a case, and chemotherapy. PMID- 4135146 TI - Immunoregulatory alpha-globulins (IRA) and tumor immunity. PMID- 4135145 TI - [Immunochemical properties of aminoenanthyl-hemoglobin and phenylalanil hemoglobin]. PMID- 4135147 TI - DNA polymerases in human lymphoblastoid cells infected with simian sarcoma virus. PMID- 4135148 TI - Enzyme histochemical studies of autotransplanted nasal septum in the rat. PMID- 4135149 TI - Eye defects of mentally handicapped children. AB - Among 171 children who received routine ophthalmic and orthoptic examinations as part of their evaluation for suspected or known developmental handicap it was found that there was an unusually high incidence of ocular defects. Especially prevalent were high refractive errors (52%) and squints (40%), but there were also a number of other serious eye defects ranging from nystagmus and cataracts to microphthalmos.Because of this high incidence of eye defects it was considered essential that ophthalmic and orthoptic examinations should be part of the routine evaluation of developmentally handicapped children by the team of workers in an assessment centre. PMID- 4135150 TI - [The alcaline phosphatase as an exponent of the secretion of the rat ovarium (author's transl)]. PMID- 4135151 TI - Corticosteroid therapy of preterminal gastrointestinal cancer. PMID- 4135152 TI - DNA complementary to globin and immunoglobulin mRNA: a probe to study gene expression. PMID- 4135154 TI - Primary lung cancer in Taiwan. I. Chronological observation of epidemiological characteristics with etiological consideration. PMID- 4135153 TI - Tribenoside as an inhibitor of chemically induced histamine release. PMID- 4135155 TI - Reliability of the tissue stamp smear cytology. PMID- 4135156 TI - Alpha-fetoprotein in liver diseases in Taiwan. PMID- 4135157 TI - [Editorial: New aspects of thyroid function exploration]. PMID- 4135158 TI - The intensification of cobalt-filled neurone profiles using a modification of Timm's sulphide-silver method. PMID- 4135159 TI - Aryl-sulfatase activity of membrane-coating granules with particular reference to their origin. PMID- 4135160 TI - Cyclic adenosine monophosphate, adenyl cyclase and cyclic nucleotide phosphodiesterase in psoriatic epidermis, with a comment on urinary cAMP. PMID- 4135161 TI - Dopa and 5-S-cysteinyldopa in malignant melanoma in Ugandan Africans. PMID- 4135162 TI - 5-S-cysteinyldopa in melanomas of Caucasians. PMID- 4135163 TI - Ultrastructure of systemic lupus erythematosus. Dermal connective tissue. PMID- 4135164 TI - Connective-tissue effects of drugs causing lupoid syndrome. PMID- 4135165 TI - Erythrohepatic protoporphyria and its treatment with beta-carotene. PMID- 4135166 TI - Iron metabolism in tetracycline-treated acne patients. PMID- 4135167 TI - The effects of polythene occlusion and topical corticosteroids on resistance to friction injury in the skin. PMID- 4135168 TI - Erythema dyschromicum perstans (ashy dermatosis). Report of two cases from Scandinavia. PMID- 4135169 TI - Generalized plane xanthomas and monoclonal IgG. PMID- 4135170 TI - Metachromatic reaction of pseudoisocyanine with sulfatides in metachromatic leukodystrophy (MLD). I. Technique of histochemical staining. PMID- 4135171 TI - Component of strain MC29 avian leukosis virus with the property of defectiveness. AB - Three clones of morphologically altered cells (L(-)MC29) of singular properties were isolated from MC29 (subgroup A) leukosis virus-infected chick embryo cells. Supernatant fluids from cultures of the cloned cells produced no transforming or interfering activity on chick embryo cells susceptible to known avian leukosis sarcoma viruses. No virus associated with the cells was demonstrable by fluorescent-antibody staining or by electron microscopy. All L(-)MC29 clone cells were activated, however, by four strains of Rous-associated viruses (RAV) representative of A, B, C, and D subgroup avian leukosis viruses and by two strains of MC29 virus. Virus L(-)MC29 cells activated by superinfection with RAV 1 and RAV-2 was characterized by helper-dependent and helper-independent properties. These findings suggest that the strain MC29 leukosis virus, or a component thereof, possesses properties of defectiveness similar to those of the Bryan high-titer Rous sarcoma virus. PMID- 4135173 TI - Oral manifestations of hypogammaglobinaemia in a young child. PMID- 4135172 TI - Structure and development of viruses as observed in the electron microscope. XI. Entry and uncoating of herpes simplex virus. AB - Two morphologically distinct types of capsids are described. The dense capsid appeared to be disrupted near the cellular membrane with release of core material. The light capsid was more stable and was frequently encountered close to the nucleus, where empty capsids were also found. Pretreatment of cells before infection with either puromycin or actinomycin D markedly decreased the percentage of empty capsids. It is suggested that the two types of capsids play different roles in the process of initiating infection. One (the dense capsid) releases deoxyribonucleic acid (DNA) shortly after entry. This DNA is transcribed into a virus-specific ribonucleic acid, which codes for an enzyme capable of altering the permeability of the second type of capsid (the light capsid). In proximity to the nucleus, the infectious DNA then escapes without gross disruption of the capsid. PMID- 4135175 TI - [Idiopathic megaesophagus and carcinoma (author's transl)]. PMID- 4135176 TI - Correlation of structural differences in several bird lysozymes and their loop regions with immunological cross-reactivity. PMID- 4135177 TI - The use of acid-isopropyl alcohol in the acid-fast staining procedure. PMID- 4135178 TI - The effect of racin on the ultrastructure of the kidney. PMID- 4135179 TI - Studies on guinea pig skin cell cultures. II. Effect of a pig skin extract on DNA synthesis. PMID- 4135180 TI - Interference with healing of rat skin incisions treated with chlorhexidine. PMID- 4135181 TI - Trace elements with suspected and hitherto unknown biological function in normal and psoriatic epidermis. PMID- 4135182 TI - Contamination of leg ulcers. A bacteriological and clinical study on the effect of treatment with an ointment containing ristocein A and circulin. PMID- 4135184 TI - Erythema dyschromicum perstans. A report of two cases in fair-skinned patients. PMID- 4135183 TI - Implantation dermatoses. PMID- 4135185 TI - Acquired (digital) fibrokeratomas. Complication of ingrown toenail. PMID- 4135186 TI - Scleredema. PMID- 4135187 TI - Compatibility of hormonal contraceptives in diabetics. Results of a questionnaire survey. PMID- 4135189 TI - [A contribution to the differential diagnosis and pathogenesis of the malignant haemangioendothliomas (author's transl)]. PMID- 4135190 TI - [Genetically controlled disorders of the human complement system]. PMID- 4135191 TI - A comparison of methods for labelling DNA for use in the radioimmunoassay of DNA antibodies. PMID- 4135192 TI - A buffered chromic chloride method of attaching antigens to red cells: use in haemagglutination. PMID- 4135193 TI - Kinetic studies of gene frequency. I. Use of a DNA copy of reticulocyte 9 S RNA to estimate globin gene dosage in mouse tissues. PMID- 4135194 TI - Kinetic studies of gene frequency. II. Complexity of globin complementary DNA and its hybridization characteristics. PMID- 4135196 TI - Do-it-yourself slides for projection: an easy way. PMID- 4135195 TI - Media systems for education and training in the allied health sciences. PMID- 4135197 TI - [Structure and function of mast cells]. PMID- 4135198 TI - [Mast cells. Uptake, production, storage and release of histamine]. PMID- 4135199 TI - [Elastic globes; histochemical and electron microscopic investigations (author's transl)]. PMID- 4135200 TI - [Bleomycin: effects on DNA and nuclear strucutre in mouse-fibroblasts (author's transl)]. PMID- 4135201 TI - Serial maternal serum alpha 1-fetoprotein concentration during induced abortions. PMID- 4135202 TI - [Detection of intracellular membranous structures in Escherichia coli cells by means of negative contrast]. PMID- 4135203 TI - [Current data and contribution to the study of hemolytic disease caused by feto maternal blood incompatibility]. PMID- 4135204 TI - [Familial idiopathic hyperlipemis: diagnostic and therapeutic considerations]. PMID- 4135206 TI - [Demonstration of parasites in toxoplasmatic lymphadenitis]. PMID- 4135205 TI - [Chlorinated pesticides in foodstuffs of animal origin]. PMID- 4135207 TI - [Regression of gingivitis following local treatment]. PMID- 4135208 TI - [Intracranial teratoma with fetuses in fetu of a premature stillborn (author's transl)]. PMID- 4135210 TI - Fluorometric scanning of fluorescamine-labeled proteins in polyacrylamide gels. PMID- 4135209 TI - A comparative study for ultrastructural localization of intracellular immunoglobulins using peroxidase conjugates. PMID- 4135211 TI - Localization within cloned rat pituitary tumor cells of material that binds antigrowth hormone antibody. PMID- 4135212 TI - Ultrastructural immunocytochemical localization of lysozyme in the Paneth cells of man. PMID- 4135213 TI - Histochemical properties of the antral gastrin cell. PMID- 4135214 TI - Skeletal changes accompanying congenital indifference to pain in two Chinese children. PMID- 4135215 TI - Ribonucleic acid dependent deoxyribonucleic acid synthesis by Escherichia coli deoxyribonucleic acid polymerase. I. Characterization of the polymerization reaction. PMID- 4135216 TI - Developmental changes in the synthesis of alpha-fetoprotein and albumin in the mouse liver. Cell-free synthesis by membrane-bound polyribosomes. PMID- 4135217 TI - Evidence for a microviscosity increase in the Escherichia coli cell envelope caused by colicin E1. PMID- 4135218 TI - Tumor virus ribonucleic acid directed deoxyribonucleic acid synthesis: nucleotide sequence at the 5' terminus of nascent deoxyribonucleic acid. PMID- 4135219 TI - Frequency of deletion of short arm satellites in acrocentric chromosomes. PMID- 4135220 TI - Translocation, t(4qminus;13qplus), in three generations resulting in partial trisomy of the long arm of chromosome 4 in the fourth generation. PMID- 4135221 TI - Letter: Cellular metachromasia with toluidine blue O in cultured white cells of cystic fibrosis heterozygotes. PMID- 4135222 TI - New trends in the chemotherapy of tuberculosis--current aspects. PMID- 4135224 TI - Inhibition of cell-dependent cytotoxicity as an assay for mouse alloantibody. PMID- 4135223 TI - Diploid, tetraploid and octaploid beta cells in the islets of Langerhans of the normal human pancreas. PMID- 4135225 TI - Viral RNA of murine sarcoma virus produced by a hamster-mouse somatic cell hybrid. PMID- 4135226 TI - Minimal bone marrow damage in mice given bleomycin. PMID- 4135227 TI - Changes in the affinity of phosphotungstic acid and positively charged colloidal particles for the surfaces of malignant human transitional epithelium of the urinary bladder. PMID- 4135228 TI - Proceedings: Phase-specific oncocolon antigens: a theoretical framework for "carcinoembryonic antigen" specificities. PMID- 4135229 TI - Binding of progesterone in the human Fallopian tube. PMID- 4135230 TI - A quantitative study of the pregnancy zone protein in the sera of pregnant and puerperal women. PMID- 4135231 TI - Prenatal sex determination by fluorescent staining of cells for the presence of Y chromatin. PMID- 4135232 TI - Repair in arterial tissue. A scanning electron microscopic (SEM) and light microscopic study on the endothelium of the rabbit thoracic aorta following noradrenaline in toxic doses. PMID- 4135233 TI - Intraventricular aberrancy versus ventricular ectopy. PMID- 4135234 TI - [Participation of gamma-globulin and specific antibodies in the formation of amyloid]. PMID- 4135235 TI - [Fibrinolytic properties of the serous membranes in fibropurulent inflammation]. PMID- 4135236 TI - [Training apparatus for the programed study of micropreparations]. PMID- 4135237 TI - Effects of colchicine on myofilament arrangement and the lysosomal system in skeletal muscle. PMID- 4135238 TI - Cytochemical demonstration of catalasepositive particles (peroxisomes?) in fibroblasts. PMID- 4135239 TI - [Morphogenesis of the respiratory epithelium in the tracheal gills of larval Limmephilini KOL. (Insecta, Trichoptera) (author's transl)]. PMID- 4135240 TI - Arterial prosthesis of lyophilised human dura origin: healing fate; scanning electron microscopy and fibrinolytic autography of graft endothelium. PMID- 4135241 TI - Kinetics of the inhibitory effect of pepstatin on the reaction of hog renin with rat plasma substrate. PMID- 4135242 TI - The "Nona" electrocardiogram: findings in 100 patients of the 90 plus age group. PMID- 4135243 TI - Histologic evidence for lipids during human tooth movement. PMID- 4135244 TI - Prospective study of outpatients with extensive colitis. PMID- 4135245 TI - Angio-immunoblastic lymphadenopathy with dysproteinaemia. PMID- 4135246 TI - Outcome in offspring of chronic alcoholic women. PMID- 4135247 TI - Humoral and cell-mediated intrinsic-factor antibody in pernicious anaemia. PMID- 4135248 TI - Plasma-immunoreactive-calcitonin in patients with non-thyroid tumours. PMID- 4135249 TI - Immediate effects of feeding on blood-gases and some cardiorespiratory functions in ill newborn infants. PMID- 4135250 TI - Editorial: Tuberculosis retreats--slowly. PMID- 4135251 TI - Editorial: Follicular lymphomas. PMID- 4135252 TI - Editorial: Malaria vaccine: promise or phantom. PMID- 4135253 TI - Editorial: Obstetric analgesia and the newborn baby. PMID- 4135254 TI - Editorial: Children in danger. PMID- 4135255 TI - Impact of the Sahelian drought in Mauritania, West Africa. PMID- 4135256 TI - How efficient is immunological surveillance against cancer and why does it fail? PMID- 4135257 TI - Letter: Brittle diabetes. PMID- 4135258 TI - Letter: The isolation of hospitals for the mentally handicapped. PMID- 4135259 TI - Letter: Nothing much for the nurses. PMID- 4135261 TI - Letter: Treatment of acute myocardial infarction. PMID- 4135260 TI - Letter: Geriatrics is medicine. PMID- 4135262 TI - Letter: Prevention of coronary heart-disease. PMID- 4135263 TI - Letter: Relevance of the relevant in teaching. PMID- 4135264 TI - Letter: Shoulder-hand syndrome. PMID- 4135265 TI - Letter: Serum F.T.I. and T.S.H. in iodine-131 treated hyperthyroidism. PMID- 4135266 TI - Letter: Human calcitonin, serum-phosphate, renal failure. PMID- 4135268 TI - Letter: Force feeding of prisoners. PMID- 4135267 TI - Letter: Virus in faecal extracts from children with gastroenteritis. PMID- 4135269 TI - Letter: Beta-trace protein and neural-tube defects. PMID- 4135270 TI - Letter: Towards the prevention of spina bifida. PMID- 4135271 TI - Letter: Cholera. PMID- 4135272 TI - Letter: Thalidomide and embryonic neuropathy. PMID- 4135273 TI - Letter: Congenital anomalies and anti-social behaviour possibly related to microbial contamination of diet. PMID- 4135274 TI - Letter: Pathogenesis of Huntington's chorea, Pick's disease, and paralysis agitans. PMID- 4135275 TI - Letter: Anti-epileptic drugs and failure of oral contraceptives. PMID- 4135276 TI - Letter: S.S.P.E. and multiple sclerosis. PMID- 4135277 TI - Letter: Acute leukaemia and myeloma. PMID- 4135278 TI - Letter: Hospital service for children with infective diseases. PMID- 4135279 TI - Letter: Acid-base changes during treatment of diabetic ketoacidosis. PMID- 4135280 TI - Letter: Lymphocyte response. PMID- 4135281 TI - Letter: Colon cancer and blood-cholesterol. PMID- 4135283 TI - Letter: Reverse transcriptase in acute leukaemia. PMID- 4135285 TI - Letter: Mo91--an allele at the first HL-A locus. PMID- 4135284 TI - Letter: Antral-gastrin-cell hyperplasia in peptic-ulcer disease. PMID- 4135282 TI - Letter: Lithium in Parkinson's disease. PMID- 4135286 TI - Letter: Arachidonic acid and retinal pigmentary degeneration. PMID- 4135287 TI - Letter: Hyponatraemia. PMID- 4135288 TI - Letter: Fetoscopy followed by live birth. PMID- 4135289 TI - Letter: HL-A and disease. PMID- 4135290 TI - George Herbert Harry Benham. PMID- 4135291 TI - [Toluidine blue staining in the diagnosis of laryngeal diseases]. PMID- 4135292 TI - [Identification of pericentric 5th chromosome in a phenotypically normal women]. PMID- 4135293 TI - Urinary protein components. 3. Classification of proteinuria based on the protein clearance results. PMID- 4135294 TI - [Histologic studies of isolated rabbit kidneys before and after surface hypothermia]. PMID- 4135295 TI - Investigations of ageing in costal and tracheal cartilage of rats. PMID- 4135296 TI - The ninth retinula cell in the ommatidium of the worker honey bee (Apis mellifica L.). PMID- 4135297 TI - The surface film on the mesothelium of the serous membranes of the rat. PMID- 4135298 TI - Effect of temperature on the function of a proton pump. PMID- 4135299 TI - The influence of radiation on blood vessels and circulation. Chapter IX. Blood flow and permeability in the central nervous system. PMID- 4135300 TI - [Indication and achievements of after-care examinations of urologic tumors. Chemotherapeutic report]. PMID- 4135301 TI - [Radiotherapy of Wilms' tumors. Combined radio and chemotherapy in the treatment of Wilms' tumors]. PMID- 4135302 TI - [Tumor-immunologic phenomena: theoretic principles, clinical importance]. PMID- 4135303 TI - [General measures for the stimulation of the body-specific defense system in tumor-patients]. PMID- 4135304 TI - [Clinical, radiological and immunological examinations substantiation in ulcerative colitis]. PMID- 4135305 TI - AV techniques in CPR teaching. PMID- 4135306 TI - [Rapid technics in the electron microscopy study of hepatocytes]. PMID- 4135307 TI - Thermally-induced changes in chromatin of isolated nuclei and of intact cells as revealed by acridine orange staining. PMID- 4135308 TI - Transfer factor: a subcellular component that transmits information for specific immune responses. AB - Two transfer factors have been prepared in an animal model system, the guinea pig. They are both small molecules, derived from the leukocytes of immunologically experienced individuals, and capable of transferring information for specific immune responses to naive individuals. PMID- 4135309 TI - Androgen receptor in rat liver: hormonal and developmental regulation of the cytoplasmic receptor and its correlation with the androgen-dependent synthesis of alpha2u-globulin. PMID- 4135310 TI - An immunosuppressive peptide fraction in the serum of cancer patients. PMID- 4135312 TI - Evidence for non-identity of T killer and T helper cells sensitised to allogeneic cell antigens. PMID- 4135311 TI - Functional characterization of blocking antibody after human renal transplantation. PMID- 4135313 TI - Type-specific protein in herpes simplex virus envelope reacts with neutralising antibody. PMID- 4135314 TI - Expression of M locus differences by B cells but not T cells. PMID- 4135315 TI - The interference of human IgG with the double-antibody radioimmunoassay of thyrotrophic hormone and its clinical significance. PMID- 4135316 TI - Alcoholic aniline blue as a stain for deoxyribonucleic acid in the Feulgen procedure. PMID- 4135317 TI - A pedunculated middle lobe of the prostate gland. PMID- 4135318 TI - Dipetalonema semiclarum sp. nov. from the blood of man in the Republic of Zaire (Nematoda : Filarioidea). PMID- 4135319 TI - Microspectrophotometric studies on the staining of DNA with violet rosaniline. PMID- 4135320 TI - Raman spectroscopic investigation of gramicidin A' conformations. AB - Gramicidin A' is believed to form transmembrane channels in lipid bilayers and biological membranes. The first Raman spectroscopic study of gramicidin A' is presented. Evidence is found for two types of conformation. One type is found in the powder and has a Raman spectrum similar to that of model polypeptides with beta hydrogen bonding. The second type is found when gramicidin A' is dissolved in dimethyl sulfoxide. PMID- 4135321 TI - Immune cytolysis of human tumor cells mediated by xenogeneic "immune" ribonucleic acid: implications for immunotherapy. PMID- 4135322 TI - Immunotherapeutic suppression in transplantable solid tumours. PMID- 4135323 TI - Rescue of defective SV40 from mouse-human hybrid cells containing human chromosome 7. PMID- 4135325 TI - [Toluidine blue in surgery of hyperthyroidism; its use in diffuse hyperplasia of the parathyroids]. PMID- 4135324 TI - Effects of thyroxine, growth hormone, and pituitary homogenates on insulin secretion and glucose uptake in thyroidectomized rats. PMID- 4135326 TI - [Hypothyroidism]. PMID- 4135327 TI - Early regression of the progestational response in rabbits after administration of progestins in the estrogen priming phase. PMID- 4135329 TI - A new look at audiovisual teaching. PMID- 4135328 TI - [1st morphological studies on Pacinian corpuscles in cystic fibrosis of the pancreas]. PMID- 4135330 TI - The rosettes and the immuno-cyto-adherence: analytic essay. PMID- 4135331 TI - Trypsin inhibition in urine of developing neonatal pigs and in sow's colostrum. PMID- 4135332 TI - Lymphocyte plasma membranes. II. Cytochemical localization of 5'-nucleotidase in rat lymphocytes. PMID- 4135333 TI - A new formula for a half-oxidized hematoxylin solution that neither overstains nor requires differentiation. PMID- 4135335 TI - Neisseria gonorrhoeae in Papanicolaou smears. PMID- 4135336 TI - [Results of transvesical prostatectomy]. PMID- 4135334 TI - Papanicolaou smear of cultured human tumor cells. PMID- 4135337 TI - Tumor scanning agents. PMID- 4135339 TI - Fluorescent bodies in the spermatozoa of patients with sterility. PMID- 4135338 TI - A visual aid to the classification of oral contraceptives. PMID- 4135340 TI - Abrogation of cell-mediated immunity by hyperimmune alloantiserum: mechanisms and correlation with allograft enhancement. PMID- 4135342 TI - Emitted cerebral events. PMID- 4135343 TI - The effect of visual feedback on physiological muscle tremor. PMID- 4135341 TI - Release of rabbit aorta contracting substance (RCS) and prostaglandins induced by chemical or mechanical stimulation of guinea-pig lungs. AB - 1. Rabbit aorta contracting substance (RCS) and prostaglandins were released from guinea-pig isolated perfused lungs by gentle massage and also by infusion of Prosparol.2. RCS and prostaglandins were also released by infusion into the pulmonary artery of bradykinin, arachidonic and dihomo-gamma-linolenic acids or shock perfusate (containing RCS-releasing factor).3. Arachidonic and dihomo-gamma linolenic acids caused a prolonged release of RCS and prostaglandins whereas bradykinin and shock perfusate gave a short-lasting output.4. RCS and prostaglandins, together with histamine were released when superfused chopped lung tissue was agitated.5. Challenge of sensitized guinea-pigs in vivo led to the release of an RCS-like substance into the carotid arterial blood.6. Intravenous injection of bradykinin into guinea-pigs also released an RCS-like substance.7. The release of RCS and prostaglandins was inhibited by aspirin or indomethacin in all experiments.8. RCS contracted all vascular tissues investigated and also rat stomach strip.9. The half-life of RCS was estimated as 1-2 minutes. PMID- 4135344 TI - Computer analysis of rabbit EEG after cerebral ischemia. PMID- 4135345 TI - Asymmetries in the electroencephalogram associated with cerebral dominance. PMID- 4135346 TI - Electromyography during voluntary movement: the two-burst pattern. PMID- 4135347 TI - Generalized penicillin epilepsy in the cat: effects of intracarotid and intravertebral pentylenetetrazol and amobarbital injections. PMID- 4135348 TI - Generalized penicillin epilepsy in the cat: effect of midbrain cooling. PMID- 4135349 TI - Simultaneous averaging of epileptic discharges in 14 channels: a computer technique. PMID- 4135350 TI - Technique of reconstruction of a cerebral hemisphere from serial sections. PMID- 4135351 TI - Somatosensory responses to stimulus trains: normative data. PMID- 4135352 TI - Somatosensory response to stimulus trains in patients with multiple sclerosis. PMID- 4135353 TI - A very stable electrode system for recording human scalp potentials with direct coupled amplifiers. PMID- 4135354 TI - Bypassing the obstructed superior vena cava with a subcutaneous long saphenous vein graft. PMID- 4135355 TI - Centromeric heterochromatin and comparison of G-banding in cattle, goat, and sheep chromosomes (Bovidae). PMID- 4135356 TI - Translocation of centromeric heterochromatin in the T(10;13) 199H stock of Mus musculus and localization of chromosome break points. PMID- 4135357 TI - Giemsa-banded chromosomes of mouse myeloma in relationship to oncogenicity. PMID- 4135358 TI - Protein granules in glial and ependymal cells in the hypophysiotropic area of the rat, stainable with aldehyde-fuchsin and chrome alum-hematoxylin. PMID- 4135359 TI - Spectral and multivariate analysis of EEG changes during mental activity in man. PMID- 4135360 TI - [Sequential analysis of PGO activity in the cat]. PMID- 4135362 TI - Evoked potentials of the central visual system during and after hypoxia in cats. PMID- 4135361 TI - Average transmission distance from mitral-tufted to granule cells in olfactory bulb. PMID- 4135363 TI - Electro-oculographic abnormalities during pursuit movements in developmental dyslexia. PMID- 4135364 TI - Sleep patterns in a patient with a brain stem infarction involving the raphe nucleus. PMID- 4135365 TI - The effect of deep hypothermia and total circulatory arrest on the electroencephalogram in children. PMID- 4135366 TI - A remote-control leucotome for neurophysiological experimentation. PMID- 4135367 TI - Epidural electrode for animals with thin skulls. PMID- 4135368 TI - Haemoglobin synthesis in inducible, uninducible and hybrid Friend cell clones. PMID- 4135369 TI - The in vivo reproductive potential of density separated cells. PMID- 4135370 TI - [Protein histochemical behavior of the normal human uterine mucosa and after several years of insertion of an intrauterine pessary]. PMID- 4135372 TI - Biophysical studies on the mechanism of quinacrine staining of chromosomes. PMID- 4135371 TI - Relationship of age of normal dogs to blood serum constituents and reliability of measured single values. PMID- 4135373 TI - Acting out and unusual behavior in schizophrenia. PMID- 4135374 TI - Distribution of heavy metals in the hippocampal region of the guinea pig. A light microscope study with Timm's sulfide silver method. PMID- 4135375 TI - Ultrastructural studies on the coronet cells of the saccus vasculosus of the freshwater stickleback, Gasterosteus aculeatus form leiurus. PMID- 4135376 TI - [Lupus erythematosus with muscular involvement and Raynaud's syndrome]. PMID- 4135377 TI - [2,2'-Bi-4-pyrones (author's transl)]. PMID- 4135378 TI - Pancreatic cancer. Initial treatment as the determinant of survival. PMID- 4135379 TI - [Action of titanium on guinea pig macrophages and human lymphocytes cultured in vitro (author's transl)]. PMID- 4135380 TI - Delayed light studies on photosynthetic energy conversion. VII. Effect of the high energy state, coupled to 2,3,5,6-tetramethyl p-phenylenediamine-catalyzed cyclic electron flow, on millisecond emission from chloroplasts and digitonin subchloroplast particles. PMID- 4135381 TI - Polymorphic nature of the human Rho (D) antigen among the red cells of non-human primates. PMID- 4135382 TI - Blood groups of non-human primates. Summary of the currently available information. PMID- 4135383 TI - Immunological and structural studies of immunoglobulins of human, chimpanzee and other non-human primates. PMID- 4135384 TI - Implications of studies in chimpanzees for the serology of the human Rh-Hr blood types. PMID- 4135385 TI - [Evaluation of antigens from various developmental stages of Ascaris suum]. PMID- 4135386 TI - Blood group antigens in primate animals and their relation to human blood groups. PMID- 4135387 TI - Trophic functions of the neuron. 3. Mechanisms of neurotrophic interactions. The role of acetylcholine as a neurotropic transmitter. PMID- 4135388 TI - Trophic functions of the neuron. 3. Mechanisms of neurotrophic interactions. Systems of material transport in nerve fibers (axoplasmic transport) related to nerve function and trophic control. PMID- 4135389 TI - Trophic functions of the neuron. VI. Other trophic systems. The influence of the periphery on spinal motor neurons. PMID- 4135390 TI - [Thyroid function tests]. PMID- 4135391 TI - [Quantitative determination of proteins in the aqueous humor and the vitreous body of the rabbit]. PMID- 4135392 TI - Isolation of skin test-active preparations from yeast-phase cells of Blastomyces dermatitidis. AB - Cell wall and cytoplasmic fractions were isolated from mechanically disrupted yeast-phase cells of Blastomyces dermatitidis in an effort to obtain a reliable skin-test antigen. The biological activities of these fractions were compared with those of two blastomycin preparations. The cytoplasmic antigens exhibited a low index of specificity yet exceeded the specificities of the blastomycins. The skin test-active component(s) of the cytoplasmic material had a molecular weight between 10,000 and 30,000 and could easily be concentrated by ultrafiltration on a PM-10 membrane. Unlike the cytoplasmic antigens and blastomycins, an alkali soluble, water-soluble cell wall antigen effectively distinguished guinea pigs that were sensitized to B. dermatitidis from those sensitized to Histoplasma capsulatum. The biological activity of the yeast-phase antigen could be quantitated, on a weight basis, after purification by ultrafiltration (PM-10 membrane). PMID- 4135393 TI - Observations on mammalian pancreatic cells grown in monolayer cultures. V. Quantitative study of the nucleolar extrusion in rat pancreatic cells cultivated in vitro. PMID- 4135394 TI - [Organogenesis of the chick pineal body. IV. Studies by the Gomori method for neurosecretion and fluorescence microscopic aspects]. PMID- 4135395 TI - [Relative importance of the spleen for antibody formation]. PMID- 4135396 TI - [Posterior vertebral fusion using an acrylic cement in the treatment of spinal tumors. Revue of 50 cases]. PMID- 4135397 TI - [Anti-variola vaccination in patients with pulmonary tuberculosis in a group previously treated by Pronison and in a group previously protected by gamma globulin]. PMID- 4135398 TI - [Clinical and therapeutic aspects of measles in the past 15 years]. PMID- 4135399 TI - Ovarian tumor-specific antigens. PMID- 4135400 TI - Letter: Cytochrome c and cytochrome oxidase in diaminobenzidine staining of mitochondria. PMID- 4135401 TI - Absence of the 9q plus chromosome in Ph1 negative chronic myelogenous leukaemia. PMID- 4135402 TI - Microphotometry of banded human chromosomes. High resolving power by direct scanning of the specimen compared with scanning on microphotographs. PMID- 4135403 TI - [Pharmacology of curare-like neuromuscular blocking agents]. PMID- 4135404 TI - [Side-effects of the curare-like agents]. PMID- 4135405 TI - Histocompatibility-linked genetic control of specific immune responses to viral infection. PMID- 4135406 TI - Folic acid effects on glycoprotein-galactosyltransferase: a re-assessment. PMID- 4135407 TI - Transcription of heteropolymeric regions of avian myeloblastosis virus high molecular weight RNA with Escherichia coli DNA polymerase I. PMID- 4135408 TI - [Anti-immunoglobulin antibodies in immunologically deficient patients. Value of their determination in intolerance reactions to therapeutic gamma globulin injections]. PMID- 4135409 TI - Nucleotide sequences of human globin messenger RNA. AB - Globin messenger RNA, isolated from human peripheral blood reticulocytes, was transcribed into complementary DNA by use of the RNA-dependent DNA polymerase of avian myeloblastosis virus. The complementary DNA was then transcribed into (32)P labeled complementary RNA by E. coli RNA polymerase in the presence of alpha (32)P-labeled ribonucleoside triphosphates. The fingerprint pattern obtained from ribonuclease T1 digests of human globin complementary RNA was specific and reproducible. Different patterns were obtained from digests of duck, mouse, and rabbit globin complementary RNA. The fingerprint patterns obtained from digests of purified natural human 10S globin messenger RNA, labeled in vitro with (125)I or with [gamma-(32)P]ATP and polynucleotide kinase, were similar to that of the complementary RNA but contained some additional oligonucleotides. Sufficient nucleotide sequence information has been obtained from about 50% of the intermediate sized oligonucleotides (8-14 base residues long), to make possible examination of correspondence between these nucleotide sequences and globin amino acid sequences. Approximately 70% of these oligonucleotide sequences can be matched to unique amino-acid sequences in the alpha- or beta-globin chains. The other 30% do not match known amino-acid sequences and presumably correspond to untranslated portions of the mRNA; some of these sequences, however, can be matched to amino-acid sequence in the abnormally long segment of the alpha chain of hemoglobin Constant Spring, which is thought to result from a chain termination mutation. PMID- 4135410 TI - Passive enhancement of canine renal allografts with polyspecific F(ab')2 fragments. PMID- 4135411 TI - Are 'N bands' selective staining of specific heterochromatin? PMID- 4135412 TI - Stimulation of angiotensinogen release by raised blood angiotensin concentration in the dog. PMID- 4135413 TI - Proceedings: The effect of thymectomy and oestrogen administration on the secondary antibody response of Swiss mice. PMID- 4135414 TI - [Hematogenic generalized candidosis as a possible complication following urologic surgery]. PMID- 4135415 TI - [Current problems in andrology]. PMID- 4135416 TI - Neoantigens on spontaneous and carcinogen-induced rat tumors defined by in vitro lymphocytotoxicity assays. PMID- 4135417 TI - Evidence for virus-specific transplantation antigen in cells of lymphoid neoplasms induced by papovavirus SV40. PMID- 4135418 TI - Rat alpha1F. XI. Immunological control of cell proliferation: increased growth rate and alpha1F production by Morris hepatoma 5123tc in rats treated with anti thymocyte serum. PMID- 4135419 TI - A comparative ultrastructural study of hepatocyte nucleolar structures observed in physiological and pathological conditions. PMID- 4135420 TI - Deoxyribonucleic acid of the crab Cancer pagurus. 3. Intracellular localization of poly d(A-T) of Cancer pagurus by hybridization in situ. PMID- 4135421 TI - Heterochromatin differentiation in Trillium kamtschaticum by ammoniacal silver reaction. PMID- 4135422 TI - The effects of the S-protein on intracranial self-stimulation in the rat. PMID- 4135423 TI - Radiotransparent electrodes for recording precordial electrocardiographic leads during catheterization. PMID- 4135424 TI - A study of the interaction of bromocresol green with isolated serum globulin fractions. PMID- 4135425 TI - [Therapeutic and prophylactic effectiveness of carbochromen in experimental myocardial infarct]. PMID- 4135426 TI - Effects of repeated heating on human albumin. PMID- 4135427 TI - The association of lung shadowing with hypersensitivity responses in patients with allergic broncho-pulmonary aspergillosis. PMID- 4135428 TI - Investigations on the innervation of the human diaphragm. PMID- 4135429 TI - [Complement anomalies and infection-related shock]. PMID- 4135430 TI - [Letter: Calcified fibro-hyaline plaques in the liver in asbestosis]. PMID- 4135431 TI - The isolation from spleen tissue of high molecular weight proteins which alter vascular permeability: investigation of their pharmacological properties. PMID- 4135432 TI - A method of evaluation of the effectiveness of dental operatory delivery systems. PMID- 4135433 TI - Mastery learning and group study in a dietetics curriculum. PMID- 4135434 TI - Insulin antibodies in diabetic pregnancy. PMID- 4135435 TI - Editorial: Incompatible physicians. PMID- 4135436 TI - Editorial: Representing the Scots. PMID- 4135437 TI - Psychiatry and political dissent. PMID- 4135438 TI - Letter: HL-A8 and HL-A12 in coeliac disease. PMID- 4135439 TI - Letter: A.C.D. and C.P.D. blood preservation. PMID- 4135440 TI - Influence of anterior hypothalamic heating on the duration of fast wave sleep episodes. PMID- 4135441 TI - Clinical studies of the evoked response to rapid random flash. PMID- 4135442 TI - Variability of the human average evoked brain response to visual stimulation: a warning. PMID- 4135443 TI - Inter-session stability of human alpha rhythm densities. PMID- 4135444 TI - Semi-automatic, multi-channel Fourier analyser for evoked potential analysis. PMID- 4135446 TI - Diurnal variation in physiological tremor. PMID- 4135445 TI - Hemispheric asymmetry: frequency analysis of visual and auditory evoked responses to non-verbal stimuli. PMID- 4135447 TI - [Electrocortical rhythms characteristic of the onset of natural sleep in the cat. Their relationship to motor activity]. PMID- 4135448 TI - The effect of caffeine, nitrazepam and cigarette smoking on the contingent negative variation in man. PMID- 4135449 TI - Computer analysis of EEG wakefulness-sleep patterns during learning of novel and familiar sentences. PMID- 4135450 TI - A complete EEG radio-telemetry equipment. PMID- 4135451 TI - A peculiar cortical electric response after low intensity visual stimulation in the dark adapted rat. PMID- 4135452 TI - Increased permeability of the rat mast cell membrane to sodium and potassium caused by extracellular ATP and its relationship to histamine release. PMID- 4135453 TI - Morphological changes induced by ATP on rat mast cells and their relationship to histamine release. PMID- 4135454 TI - Reciprocal tachycardia using a left-sided bypass (type A) in patients with type B Wolff-Parkinson-White. PMID- 4135455 TI - [Bleomycin alone and in combination with methotrexate in the treatment of carcinoma of the esophagus (author's transl)]. PMID- 4135456 TI - [Diagnosis of brain tumors using current scintigraphic methods]. PMID- 4135457 TI - [After-care examinations in Hodgkin's disease. Internal medicine and chemotherapy]. PMID- 4135458 TI - [Preoperative irradiation in Wilms' tumor]. PMID- 4135459 TI - Pulmonary fibrosis following multiple treatment with bleomycin (NSC-125066) in dogs. PMID- 4135460 TI - Treatment of non-Hodgkin's lymphoma. Standard treatment. PMID- 4135461 TI - [Histochemical localization of the active ion transport in ther parotid gland of adult cattle]. PMID- 4135462 TI - [Exercise test. Risks and medico-legal repercussions]. PMID- 4135463 TI - Yeast- and mycelial-phase antigens of Blastomyces dermatitidis: comparison using disc gel electrophoresis. AB - The disc gel electrophoretic patterns obtained with skin test-active (mycelial and yeast) antigens of Blastomyces dermatitidis were compared. As would be expected, the blastomycins (mycelial-phase) and the cytoplasmic ultrafiltrates (yeast-phase) were heterogeneous mixtures containing proteins, glycoproteins, lipoproteins, and carbohydrates. The skin test-active cytoplasmic ultrafiltrates and the blastomycins contained glycoproteins that had similar R(f) values which allows the possibility that one or more of these components is responsible for the skin-test reactivity of these antigens. The electrophoretic migration of the alkali-soluble, water-soluble cell wall antigen differed from those of the cytoplasmic antigens and the two blastomycins. Electrophoresis, Sephadex chromatography, and ultrafiltration studies showed that the alkali-soluble, water soluble cell wall antigen is comprised of lipid, polysaccharide, and protein and has a molecular weight range of 30,000 to 50,000. The increased number and mobility of both the protein and carbohydrate bands after denaturation and electrophoresis of this antigen in sodium dodecyl sulfate indicate that there are several cross-linkages between the polysaccharide and/or protein moieties, possibly via lipid or disulfide bridges. PMID- 4135464 TI - [Neuromuscular-blocking agents. 2nd round table. The role of neuromuscular blocking agents in resuscitation]. PMID- 4135465 TI - Interactions of antibodies, complement components and various cell types in immunity against viruses and pyogenic bacteria. PMID- 4135466 TI - Hyperthyroidism and pregnancy. PMID- 4135467 TI - Treatment of Hodgkin's disease. PMID- 4135468 TI - The sex chromosomes of the Chinese hamster: constitutive heterochromatin deficient in repetitive DNA sequences. PMID- 4135470 TI - Acoustic jaw reflex in man: its relationship to other brain-stem and microreflexes. PMID- 4135469 TI - Cytology of the pituitary gland of the Indian desert gerbil Meriones hurrianae Jerdon. PMID- 4135471 TI - Modifications of pulvinar and geniculo-cortical evoked potentials during visual discrimination learning in monkeys. PMID- 4135472 TI - Lysosomes of the arterial wall. IV. Cytochemical localization of acid phosphatase and catalase in smooth muscle cells and foam cells from rabbit atheromatous aorta. AB - Cytochemical methods for acid phosphatase and catalase were applied to atheromatous aortas from cholesterol-fed rabbits. Whole tissue, partially digested aortic slices and isolated cells were used for the study. Present in the atheromatous lesions were smooth muscle cells in all stages of foamy transformation, from virtually normal appearing smooth muscle cells to severely altered cells with pronounced lipid accumulation. The results with the acid phosphatase method show that lysosomes increase both in size and in number as the smooth muscle cells become foam cells. In normal appearing smooth muscle cells, acid phosphatase reaction product was found in stacked cisternae of the Golgi apparatus and in small vesicles located in the Golgi region and distributed throughout the cytoplasm. In foam cells, reaction product was found in membrane limited vacuoles of varying size which typically contained membranous debris or myelin-like figures together with massive lipid deposits. No reaction was seen in "free" cytoplasmic lipid droplets lacking a surrounding membrane. These results confirm and extend previous biochemical findings indicating that, in the cholesterol-fed rabbit, the change from normal smooth muscle cell to foam cell is accompanied by marked physical and chemical changes of the lysosomes, including their progressive overloading with cholesteryl ester. Small diaminobenzidine positive particles were present in normal smooth muscle cells and in those at all stages of foamy transformation. These particles were more frequent in foam cells, in agreement with the marked increase in catalase activity detected biochemically in these cells. PMID- 4135473 TI - Liver histamine and zinc in guinea pig anaphylaxis. PMID- 4135474 TI - Sister chromatid exchanges induced by light flashes to 5-bromodeoxyuridine- and 5 iododeoxyuridine substituted Chinese hamster chromosomes. PMID- 4135475 TI - Fluorescent staining of L cell centromeres and chromocenters with 1 dimethylaminonaphthalene-5-sulfonyl chloride and G-bandings. PMID- 4135476 TI - The hemolytic uremic syndrome, with positive immunofluorescence studies. PMID- 4135477 TI - Neonatal hypothyroidism and goiter in one infant of each of two sets of twins due to maternal therapy with antithyroid drugs. PMID- 4135478 TI - In vitro characteristics of a myxopapillary ependymoma of the filum terminale maintained in tissue and organ culture systems. Light and electron microscopic observations. PMID- 4135479 TI - Developing an activity program in a welfare hotel. PMID- 4135480 TI - [Thyroid hormonosynthesis disorders due to iodotyrosine-dehalogenase deficiency. Value of the D.I.T. test for the detection of heterozygotes]. PMID- 4135481 TI - Editorial: DNA polymerase and hepatitis B antigen. PMID- 4135482 TI - On the diagnosis and treatment of sinoatrial disease with special reference to sinoatrial Wenckebach. PMID- 4135483 TI - Adrenergic mechanisms and immediate-type allergy. PMID- 4135484 TI - Morphological classification of rat incisor ameloblasts. PMID- 4135485 TI - Localization of muscle spindles in the human Extensor Indicis muscle for biopsy purposes. PMID- 4135486 TI - [Experimental Wallerian degeneration in the vestibular nuclei: study by light and electron microscopy after silver staining (author's transl)]. PMID- 4135487 TI - Intensive intravenous regimen for severe attacks of ulcerative colitis. PMID- 4135488 TI - Frequency of mycoplasma in fertile and infertile couples. PMID- 4135489 TI - Editorial: On the rocks. PMID- 4135490 TI - Editorial: Trachoma. PMID- 4135491 TI - Editorial: Childproofing the medicines bottle. PMID- 4135492 TI - Vibrio parahaemolyticus food-poisoning in Britain. PMID- 4135493 TI - Letter: American Medical Association. PMID- 4135494 TI - Letter: Phosphoglucose isoenzymes in spermatozoa. PMID- 4135495 TI - Letter: Small doses of intramuscular insulin in the treatment of diabetic "coma". PMID- 4135496 TI - Letter: Bowie and Dick test. PMID- 4135497 TI - Letter: Prostaglandin-F2alpha receptor in human corpora lutea. PMID- 4135498 TI - Ida Macalpine. PMID- 4135499 TI - Evaluating a self-instructional module in quantity food purchasing. PMID- 4135500 TI - Relation between benign prostatic hyperplasia and cancer of the prostate. A prospective and retrospective study. PMID- 4135501 TI - Survival of patients with late ventricular fibrillation after acute myocardial infarction. PMID- 4135502 TI - Prolonging remission in myeloblastic leukemia by tice-strain bacillus Calmette Guerin. PMID- 4135503 TI - Hodgkin's disease mortality among physicians. PMID- 4135504 TI - Beta-o thalassemia--time for a reappraisal? PMID- 4135505 TI - Editorial: Tuberculosis of the spine. PMID- 4135507 TI - Editorial: Who defends the patient? PMID- 4135508 TI - Editorial: Ballon v. bladder. PMID- 4135506 TI - Editorial: Microbial-antigen detection. PMID- 4135509 TI - Issues in National Health Insurance in the United States of America. PMID- 4135510 TI - Clinical effects on drug abuse of a conviction for a drug offence. PMID- 4135511 TI - Letter: HBAg in breast milk. PMID- 4135512 TI - Letter: Blood fractions for haemophilia. PMID- 4135513 TI - Letter: D.N.C.B. test in hepatitis. PMID- 4135514 TI - Letter: Respiratory filters in clinical practice. PMID- 4135515 TI - Letter: Cannulation of the radial artery. PMID- 4135516 TI - Letter: Klebsiella in hospital-acquired infections. PMID- 4135517 TI - Letter: Ampicillin-resistant Haemophilus influenzae. PMID- 4135518 TI - Letter: Postoperative gynaecological wound infection. PMID- 4135519 TI - Letter: Immune competence in Crohn's disease. PMID- 4135520 TI - Letter: Paget's disease as hereditary defect of connective tissue. PMID- 4135521 TI - Letter: Haemodialysis in multiple trauma. PMID- 4135522 TI - Letter: Transfer factor in adult rheumatoid arthritis. PMID- 4135523 TI - Letter: Serum-gentamicin levels after intravenous bolus injection. PMID- 4135524 TI - Letter: Adriamycin in acute leukaemia. PMID- 4135525 TI - Letter: Synthetic prostaglandin in gastric ulcer. PMID- 4135526 TI - Letter: Uterine hypertonus after oral prostaglandin E2. PMID- 4135527 TI - Letter: Measurement of skin blood-pressure. PMID- 4135528 TI - Letter: B lymphocytes during ageing. PMID- 4135529 TI - Letter: Lysine metabolism in Reye's syndrome. PMID- 4135530 TI - Letter: Hyponatraemia. PMID- 4135531 TI - Letter: Serum-cholesterol and dietary carbohydrates. PMID- 4135532 TI - Letter: Pathologists at the crystal ball. PMID- 4135533 TI - Letter: "Menstrual toxin". PMID- 4135534 TI - Letter: Tonsillectomy and Hodgkin's disease. PMID- 4135535 TI - Letter: Variation of stump volume after below-knee amputation. PMID- 4135536 TI - Letter: Probability of death related to previous army rank. PMID- 4135537 TI - Letter: Klinefelter's syndrome in a fetus. PMID- 4135538 TI - Letter: Anti-oestrogens and breast cancer. PMID- 4135539 TI - Letter: Classification of anti-tumour drugs. PMID- 4135540 TI - Letter: Maternal smoking and neonatal hyperbilirubinaemia. PMID- 4135541 TI - Letter: Cerebral intravascular coagulation in diabetic ketocidosis. PMID- 4135542 TI - Letter: Measuring malnutrition. PMID- 4135543 TI - Letter: Alpha-fetoprotein in Indian childhood cirrhosis. PMID- 4135544 TI - Letter: Aetiology of kwashiorkor. PMID- 4135545 TI - Letter: Oral contraception and sex ratio. PMID- 4135546 TI - Letter: Action of cyproterone acetate. PMID- 4135547 TI - Letter: Serotyping Neisseria meningitidis. PMID- 4135548 TI - Letter: Proguanil and mouth ulcers. PMID- 4135549 TI - Rhythmic activity of a group of human motoneurones during voluntary contraction of a muscle. PMID- 4135550 TI - Systemic lupus erythematosus with signs of retroperitoneal fibrosis. PMID- 4135551 TI - [Postsplenectomy changes in serum protein levels, their origin and possible significance]. PMID- 4135552 TI - Structural features of histamine release in rat peritoneal mast cells. A study with toluidine blue. PMID- 4135553 TI - Keratin bodies. A clue in the cytological detection of endometrial adenoacanthoma. Report of two cases. PMID- 4135554 TI - Letter: Breast cancer at site of implantation of pacemaker generator. PMID- 4135555 TI - [Hypothyroidism due to congenital abnormality of thyroglobulin synthesis. Apropos of 3 cases]. PMID- 4135556 TI - Heparin versus dextran in the prevention of deep-vein thrombosis. A multi-unit coctrolled trial. PMID- 4135558 TI - Editorial: Dimethyltryptamine and psychosis. PMID- 4135557 TI - Intestinal absorption of 25-hydroxycholecalciferol. PMID- 4135560 TI - Letter: Industrial action by radiographers. PMID- 4135559 TI - The general-practice dilemma. PMID- 4135561 TI - Letter: D.N.A. binding in rheumatoid arthritis. PMID- 4135562 TI - Letter: Allopurinol in leukaemias and lymphomas. PMID- 4135563 TI - Letter: Plasma-calcitonin and non-thyroid tumours. PMID- 4135564 TI - Letter: Positive feedback from a Royal College. PMID- 4135565 TI - Letter: Abdominal pain after intravenous benzylpenicillin. PMID- 4135566 TI - Letter: Origin of Hodgkin's cell. PMID- 4135567 TI - Letter: Catalin, quinones, and cataract. PMID- 4135568 TI - Letter: Vaginal smears after total hysterectomy. PMID- 4135569 TI - Letter: Rifampicin and immunosuppression. PMID- 4135570 TI - Letter: Specificity of N.B.T. test. PMID- 4135571 TI - Letter: Maldescended testes. PMID- 4135572 TI - Gordon Chester Kennedy. PMID- 4135573 TI - Anna Josephine Mayr-Harting. PMID- 4135574 TI - Biosyntheses of new bleomycins. PMID- 4135575 TI - [Intranuclear inclusions in Waldenstrom's disease. Their biological significance and diagnostic value]. PMID- 4135576 TI - [Letter: Consistency of alteration of alveolo-capillary transfer in man, due to an anti-tumor agent (bleomycin)]. PMID- 4135577 TI - [Impossibility of detecting heterozygote mucopolysaccharidosis by lymphocyte metachromasia in culture]. PMID- 4135578 TI - Physical growth and development, neurological maturation, and behavioral functioning in two Ecuadorian Andean communities in which goiter is endemic. II. PTC taste sensitivity and neurological maturation. PMID- 4135579 TI - Bronchial asthma produced by paranasal sinusitis. PMID- 4135580 TI - Hypersensitivity to intravenous morphine sulfate. PMID- 4135581 TI - Restoration of specific immunological virginity. PMID- 4135582 TI - Stimulatory capacity of human T and B lymphocytes in the mixed leukocyte culture. PMID- 4135583 TI - Reduced axoplasmic transport of choline acetyltransferase activity in dystrophic mice. PMID- 4135584 TI - Kynurenine formamidase. Purification and characterization of the adult chicken liver enzyme and immunochemical analyses of the enzyme of developing chicks. PMID- 4135586 TI - Faculty time expenditures for an audiovisual periodontology course. PMID- 4135585 TI - Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology. AB - Of 60 TRIC agents isolated from Gambian children with trachoma, 25 were serotype 1 and the remainder type 2. There was a pronounced difference in the proportions of these types in the two villages studied. In the village with a predominance of type 2 strains, TRIC agents remained confined to 2 adjacent compounds over a 14 month observation period. All 19 type 1 strains examined were characterized by the appearance in yolk sac smears of compact aggregates of elementary bodies; such aggregates were seen in only 2 of 35 type 2 strains, and may reflect a chemical difference in the surface of the elementary bodies or in a substance elaborated during their replication. PMID- 4135587 TI - Down and Klinefelter syndromes (48, XXY, G+) in a young man. Cytogenetic, endocrine, and testicular steroidogenesis studies. PMID- 4135588 TI - Experimental allergic encephalomyelitis in triethyltin sulfate-treated brown Norwegian and Lewis rats. PMID- 4135589 TI - Intercellular junctions of the tracheal epithelium in guinea pigs. PMID- 4135590 TI - Morphometric analysis of sarcomas with different karyotypes. PMID- 4135591 TI - Alpha-1-fetoprotein and alcoholic hepatitis. PMID- 4135592 TI - A hormonally influenced human serum globulin: elevation of Xh by estrogen. PMID- 4135593 TI - The cold-insoluble globulin of plasma and its relationship to factor VIII. PMID- 4135594 TI - A simplified platelet factor 3 (PF-3) assay for the rapid detection of platelet isoantibodies and an antiplatelet factor in ATP and SLE. PMID- 4135595 TI - Fiber types in the human brachial biceps muscle. PMID- 4135596 TI - Human immune response to active immunization with Rauscher leukemia virus. I. Cell-mediated and cell-associated immunity. PMID- 4135597 TI - Characteristics of an established cell line of retinoblastoma. PMID- 4135598 TI - Detection of Mason-Pfizer virus infection with human KC cells carrying Rous virus genome. PMID- 4135599 TI - Plaque assay for the Mason-Pfizer monkey virus. PMID- 4135600 TI - Transplantation isoantigenicity of a rat sarcoma and its spontaneous metastases. PMID- 4135601 TI - Presence of A-type and absence of C-type virus particles in a chemically induced guinea pig hepatoma. PMID- 4135602 TI - Application of radioimmunoassay to pharmacology. PMID- 4135603 TI - Late recurrence of testicular tumor. PMID- 4135604 TI - The effects of various manipulations on serum phosphatase levels in benign disease. PMID- 4135605 TI - Value of radiotherapy for adenocarcinoma of the prostate simulating primary rectal carcinoma. PMID- 4135606 TI - Association of Reye's syndrome with viral infection. PMID- 4135607 TI - Modulation, by food, of hormonal system regulating rat pancreatic secretion. PMID- 4135608 TI - Diagnosis of insulinomas by suppression tests. PMID- 4135609 TI - Risk of transfusing blood containing antibody to hepatitis-B surface antigen. PMID- 4135610 TI - Seasonal occurrence of complex ventricular septal defect. PMID- 4135611 TI - Effect of meals on rifampicin absorption. PMID- 4135612 TI - Peak-flow meter versus peak-flow gauge. PMID- 4135613 TI - Editorial: What price the N.H.S.? PMID- 4135614 TI - Editorial: Renal-artery stenosis and renal failure. PMID- 4135615 TI - Editorial: Gram-negative infective polyarthritis. PMID- 4135616 TI - Editorial: Reorganization on Humberside. PMID- 4135617 TI - Editorial: Colonic explosions. PMID- 4135618 TI - Multi-infarct dementia. A cause of mental deterioration in the elderly. PMID- 4135619 TI - Medical work and social power. PMID- 4135620 TI - Letter: Pathogenesis and natural history of porphyria cutanea tarda. PMID- 4135621 TI - Letter: Industrial action in the N.H.S. PMID- 4135622 TI - Letter: Inequality and the health service. PMID- 4135623 TI - Letter: Role of the community physician. PMID- 4135624 TI - Letter: Domiciliary physiotherapy service. PMID- 4135625 TI - Letter: Pathologists, thechnologists, crystal balls, or vipers in the bosom. PMID- 4135626 TI - Letter: Lack of antigenic correlation between chicken brain and thymus. PMID- 4135627 TI - Letter: Vitamins in the elderly. PMID- 4135628 TI - Letter: Treatment of paracetamol overdosage. PMID- 4135629 TI - Letter: Subpopulations of B lymphocytes in human tonsils and peripheral blood. PMID- 4135630 TI - Letter: Mixed receptors. PMID- 4135631 TI - Letter: T and B lymphocytes. PMID- 4135632 TI - Letter: Depression of lymphocyte transformation in women taking oral contraceptives. PMID- 4135633 TI - Letter: Quantitative bone scanning. PMID- 4135634 TI - Letter: Teaching biochemistry to medicals. PMID- 4135635 TI - Letter: Maternal alcoholism and intellectual development of offspring. PMID- 4135636 TI - Letter: Peptic ulcer in childhood. PMID- 4135637 TI - Letter: Hepatitis-B antigen and tobacco plants. PMID- 4135638 TI - Letter: Milk antibodies and myocardial infarction. PMID- 4135639 TI - Letter: Fibrinolytic activity and treatment of diabetes. PMID- 4135640 TI - Letter: Fate of 125I-labelled fibrinogen. PMID- 4135641 TI - Letter: Increased warfarin requirement during mercaptopurine therapy: a new drug interaction. PMID- 4135642 TI - Letter: Varieties of von Willebrand's disease. PMID- 4135644 TI - Letter: Kwashiorkor and tuberculosis. PMID- 4135643 TI - Letter: Mechanism of the anti-aggregating effect of aspirin on human platelets. PMID- 4135645 TI - Letter: Hypochromotrichia in malnutrition. PMID- 4135646 TI - Editorial: Dilating oesophageal strictures. PMID- 4135647 TI - Letter: Cannulation of radial artery. PMID- 4135648 TI - Letter: Limulus assay for gram-negative endotoxin. PMID- 4135649 TI - Letter: Depression of D.N.A.-polymerase activity by lithium. PMID- 4135650 TI - Letter: The 47 XXY karyotype. PMID- 4135651 TI - Letter: Dangers in nuclear-sexing the fetus. PMID- 4135652 TI - Letter: 8-21 translocation and missing sex chromosomes in acute leukaemia. PMID- 4135653 TI - Letter: Follow-up of urinary-tract infection in children. PMID- 4135654 TI - Letter: Dip test for bacteriuria. PMID- 4135655 TI - Letter: Treatment by vertebral manipulation. PMID- 4135656 TI - Letter: Acute arthralgia following high-dose intravenous methylprednisolone therapy. PMID- 4135658 TI - Letter: Hypertrophy of extensor digitorum brevis in limb-girdle muscular dystrophy. PMID- 4135657 TI - Letter: Diagnosis of superior-vena-cave obstruction. PMID- 4135659 TI - Letter: Stimulation of the spinal cord in motor-neurone disease. PMID- 4135661 TI - Letter: Dietary carbohydrate and serum-cholesterol. PMID- 4135660 TI - Letter: Prolactin and migraine. PMID- 4135662 TI - Letter: Medical nemesis. PMID- 4135663 TI - Letter: Fusidic acid in psoriasis. PMID- 4135664 TI - Letter: Rifampicin and drug metabolism. PMID- 4135665 TI - Charles Edward Lumsden. PMID- 4135666 TI - Victor Ewings Negus. PMID- 4135667 TI - [Surgical treatment of hemorrhaging esophageal varices]. PMID- 4135668 TI - Letter: Lipophilic paraproteins. PMID- 4135669 TI - [Computer analysis of the electrocardiogram with different programmes. II. Analysis of arrhythmias (author's transl)]. PMID- 4135670 TI - [Problems in the computer evaluation of electrocardiograms]. PMID- 4135671 TI - Immunologic diagnosis of human cancers. PMID- 4135672 TI - Antigenicity of fetal and adult cerebral tissue of man. PMID- 4135673 TI - Preliminary results of a computer logic program for the operative management of colon cancer. PMID- 4135674 TI - Gametocytes, sporozoites and liver schizonts. PMID- 4135675 TI - [Indication and technic of limited surgery for breast carcinoma]. PMID- 4135676 TI - [Improved evaluation criteria of autonomous thyroid adenoma: triiodothyronine concentration in serum, functional definition through TRH test]. PMID- 4135678 TI - [Letter: Nycturia in prostatic hypertrophy]. PMID- 4135677 TI - [Drug therapy of tuberculosis]. PMID- 4135679 TI - The nature of ventricular ectopic beats in chronic ischaemic heart disease. PMID- 4135680 TI - Effect of vitamin A alcohol on the surface coat and charges of L1210 leukemic cells. PMID- 4135681 TI - Mammary carcinogenesis in foster-nursed X-Gf mice. PMID- 4135682 TI - Phase II study of concurrent methotrexate and bleomycin chemotherapy. PMID- 4135683 TI - 5-azacytidine-modified patterns of uridine kinase activities in normal and neoplastic tissues. PMID- 4135684 TI - Evidence in favor of the existence of human breast cancer virus. PMID- 4135685 TI - Responses of cycling and noncycling cells to 1,3-bis(2-chloroethyl)-1-nitrosourea and to bleomycin. PMID- 4135686 TI - Controlled clinical trial of four short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis. Third report. East African-British Medical Research Councils. PMID- 4135687 TI - A clinical trial of the treatment of haemorrhoids by operation and the Lord procedure. PMID- 4135688 TI - Effect of different doses of chenodeoxycholic acid on bile-lipid composition and on frequency of side-effects in patients with gallstones. PMID- 4135689 TI - Editorial: Bone necrosis in divers. PMID- 4135690 TI - Editorial: Iatrogenic hip disease. PMID- 4135691 TI - Editorial: Laparotomy-the final court of appeal? PMID- 4135692 TI - Editorial: Deviance in the classroom. PMID- 4135693 TI - Editorial: Health policy and medical education. PMID- 4135694 TI - Subnormality and its relation to psychiatry. PMID- 4135695 TI - Ocular vaccinia. PMID- 4135696 TI - Letter: Protein requirement. PMID- 4135697 TI - Letter: Hunger in Mauritania. PMID- 4135698 TI - Letter: Thermosensitive transfer factors in chloramphenicol-resistant strains of Salmonella typhi. PMID- 4135699 TI - Letter: Imperialism: chloramphenicol. PMID- 4135700 TI - Letter: Geriatrics. PMID- 4135701 TI - Letter: Private practice. PMID- 4135702 TI - Letter: Industrial action in the N.H.S. PMID- 4135703 TI - Letter: Co-trimoxazole and the blood. PMID- 4135704 TI - Letter: Peptic ulceration and D-penicillamine. PMID- 4135706 TI - Letter: General-practice dilemma. PMID- 4135705 TI - Letter: Subnormality at the crossroads. PMID- 4135707 TI - Letter: Rejection. PMID- 4135708 TI - Letter: Bleeding and perioperative heparin. PMID- 4135709 TI - Letter: Subcutaneous heparin and postoperative deep venous thrombosis. PMID- 4135710 TI - Letter: Childproofing the medicines bottle. PMID- 4135711 TI - Letter: HL-A and disease. PMID- 4135712 TI - Letter: HL-A and idiopathic Addison's disease. PMID- 4135713 TI - Letter: Claims for a diathermy machine. PMID- 4135714 TI - Letter: Academics in the community. PMID- 4135715 TI - Letter: Bubbles show air movement in operating-theatres. PMID- 4135716 TI - Letter: National health insurance in the U.S.A. PMID- 4135717 TI - Letter: Angio-immunoblastic lymphadenopathy with dysproteinaemia. PMID- 4135718 TI - Letter: Suppression of delayed hypersensitivity in Graves' disease. PMID- 4135719 TI - Letter: Macronumbers of microorganisms. PMID- 4135720 TI - Letter: Bone-marrow preparations in chromosome studies. PMID- 4135721 TI - Letter: Methods of B.C.G. vaccination. PMID- 4135722 TI - Letter: Benign prostatic hyperplasia. PMID- 4135723 TI - Letter: Mortality in agranulocytosis. PMID- 4135724 TI - Letter: Serum-complement levels in haemolytic-uraemic syndrome. PMID- 4135725 TI - Letter: Impaired neutrophil phagocytosis. PMID- 4135726 TI - Letter: Antibiotics and neonatal hyperbilirubinaemia. PMID- 4135727 TI - Letter: Familial aggregation in nasopharyngeal carcinoma. PMID- 4135728 TI - Letter: HL-A typing and kidney transplantation. PMID- 4135729 TI - Letter: T and B lymphocytes in liver. PMID- 4135730 TI - Letter: Diet for diabetics. PMID- 4135731 TI - Letter: A shower of aortic aneurysms. PMID- 4135732 TI - Letter: Danger of varicella to immunosuppressed patients. PMID- 4135733 TI - Letter: Coagulase-negative Staphylococci in the urinary tract. PMID- 4135734 TI - Letter: Self and not-self. PMID- 4135735 TI - Letter: Another blood product. PMID- 4135736 TI - Letter: Colonies of Trichomonas vaginalis on Mycoplasma medium. PMID- 4135737 TI - Letter: Blood fractions for haemophilia. PMID- 4135738 TI - Selective immunosuppression using antigens and antibodies as pharmacologic agents. PMID- 4135739 TI - Drug-induced autoimmune disease. PMID- 4135740 TI - A review of development of adipose cellularity in man and animals. PMID- 4135741 TI - [Cytodiagnosis of tumors of the gastrointestinal system]. PMID- 4135742 TI - Recent results of two-stage surgical treatment of large ventricular septal defect. PMID- 4135743 TI - Atrial septectomy in patients with D-transposition of the great arteries, ventricular septal defect, and severe pulmonary vascular obstructive disease. PMID- 4135744 TI - Transventricular mitral valvulotomy. Analysis of factors influencing operative and late results. PMID- 4135745 TI - The diagnosis of thyrotoxicosis. PMID- 4135746 TI - Proceedings: The identification of two platelet specific release products. PMID- 4135747 TI - The interaction of dihydrotestosterone and oestradiol-17beta with macromolecules in human hyperplastic prostate tissue. PMID- 4135748 TI - Lability of human decidual cells. In vivo effects of hypertonic saline. PMID- 4135749 TI - Reply to letter. The possibility of diagnosing lower genital tract infections with Corynebacterium vaginale by means of wet mounts and stained smears. PMID- 4135750 TI - Thrombin stimulated release of platelet microfibrils. PMID- 4135751 TI - [Immunohistochemical investigations in T-lymphocytes of the mouse]. PMID- 4135752 TI - [Electron microscopy study on the erythropoiesis in fetal rat liver (day 14 a.p.) following administration of chloramphenicol and oxytetracycline]. PMID- 4135753 TI - Amniotic fluid beta-2 microglobulin concentration--an index of gestational age. PMID- 4135754 TI - Antenatal fetal sex determination from maternal blood during early pregnancy. PMID- 4135755 TI - Mechanism of histamine release from guinea-pig lung by soluble immune complexes. II. Role of anaphylatoxin. PMID- 4135756 TI - The ossification process of the developing antler in the white-tailed deer (Odocoileus virginianus). PMID- 4135757 TI - Histological preparation of bone to study ingrowth into implanted materials. PMID- 4135758 TI - Measurement of growth and resorption of bone in the seventh caudal vertebra of the rat. PMID- 4135760 TI - Reverse transcriptase in normal rhesus monkey placenta. AB - Particles with the morphology of type C virus have been identified from primate placentas by electron microscopy. A reverse transcriptase (RNA-dependent DNA polymerase) was isolated and purified from microsomal pellets of two fresh placentas of rhesus monkeys in the early stages of gestation. This enzyme was biochemically similar yet immunologically distinct from the reverse transcriptases of known tumorigenic type C RNA viruses isolated from primates, but was immunologically related to a reverse transcriptase isolated from a type C virus obtained from normal baboon placenta. These particles may represent endogenous viruses and may function in the transfer of genetic information during embryogenesis. PMID- 4135759 TI - Histochemical studies on calcified tissues. I. Amino acid histochemistry of foetal calf and human enamel matrix. PMID- 4135761 TI - An electron microscopic study of some protein fractions from bovine erythrocyte ghosts. PMID- 4135762 TI - Non-specific binding of proteins by substituted agaroses. PMID- 4135763 TI - Retinoblastoma at Groote Schuur Hospital 1952-1972. PMID- 4135764 TI - Laboratory problems in the diagnosis of trachoma. PMID- 4135765 TI - Malignant melanoma of the choroid a review of the histopathology of 100 cases. PMID- 4135766 TI - Nutritional and metabolic aspects of heredopathia atactica polyneuritiformis (Refsum's syndrome). PMID- 4135767 TI - Estradiol-17beta-hydroxysteroid dehydrogenase activity in preimplantation rat embryos. PMID- 4135768 TI - [Substantiation of Theodor Leber's teaching on circulation of intraocular fluid 100 years ago (author's transl)]. PMID- 4135769 TI - [The existence of goitres in the triton Pleurodeles waltlii. A comparative study of the thyroid function in goitrous and healthy urodelous amphibians (author's transl)]. PMID- 4135770 TI - Treatment of malignant esophageal obstruction by endoesophageal intubation. PMID- 4135771 TI - Etiologic factors in ulcerative colitis: birth, death and symbolic equivalents. PMID- 4135772 TI - S-tropic murine type-C viruses: frequency of isolation from continuous cell lines, leukemia virus preparations and normal spleens. PMID- 4135773 TI - Detection in human melanoma cell lines of particles with some properties in common with RNA tumour viruses. PMID- 4135774 TI - Genetic control of susceptibility to 3-methylcholanthrene-induced subcutaneous sarcomas. PMID- 4135775 TI - Proceedings: Anaphylactic release of prostaglandins, slow-reacting substance, and histamine, and its modification by sympathomimetics. PMID- 4135776 TI - Proceedings: Temporal relationship between rat liver histone acetylation and nuclear RNA polymerase activities after alpha-hexachlorcyclohexan application. PMID- 4135777 TI - Proceedings: The influence of glucocorticoids on the stimulability of adenyl cyclase and the anaphylactic histamine release in the guinea pig lung in vitro. PMID- 4135778 TI - Proceedings: Arterial and venous blood histamine levels after I.V. administration of histamine liberators in the dog in vivo. PMID- 4135779 TI - Proceedings: Control by feeding habits of the induction of hepatic DNA synthesis by alpha-hexachlorocyclohexane. PMID- 4135780 TI - Proceedings: Influence of oxymetazoline and phentolamine on noradrenaline (NA) release caused by electrical stimulation, potassium, tyramine and dimethylphenylpiperazine (DMPP). PMID- 4135781 TI - Alpha 1-antitrypsin deficiency associated with PZ and MP phenotypes. Clinical and laboratory correlations. PMID- 4135782 TI - Sjogren-Larsson syndrome. Oligophrenia--ichthyosis--di-tetraplegia. PMID- 4135783 TI - Effect of G-banding techniques on the ultrastructure of human chromosomes. PMID- 4135784 TI - Strongly fluorescent chromosome bands in metaphase and interphase. PMID- 4135785 TI - Direct Giemsa-banding pattern analysis of human chromosomes by means of a television microdensitometer: the Quantimet 720D. PMID- 4135786 TI - Identification of a large submetacentric X chromosome as pericentric inversion of an isochromosome of the long arm. PMID- 4135787 TI - 45,X-45,X, ace(?Yp)plus-46,X,r(Y) in a phenotypically normal newborn male. PMID- 4135788 TI - [Postradiation sensitization of cells of the blue-green alga Anacystis nidulans by means of dimethylbenzylrifampicin--an active inhibitor of RNA-dependent DNA polymerase]. PMID- 4135789 TI - Use of sodium hydroxide in the preparation of epidermal peels from certain coniferous leaves rich in resins and tannins. PMID- 4135790 TI - Collecting human chromosomes for whole-mount electron microscopy. PMID- 4135791 TI - A simple assay procedure for mixtures of hematoxylin and hematein. PMID- 4135792 TI - A method for obtaining longitudinal cryostat sections of living muscle without contraction artifacts. PMID- 4135793 TI - A method for the selective removal of deoxyribonucleic acid from tissue sections. PMID- 4135794 TI - A simple silver solution for staining reticulin. PMID- 4135795 TI - Oriented embedding of single-cell organisms. PMID- 4135796 TI - Toluidine blue staining of coccidia in cultured animal cells. PMID- 4135797 TI - Some observations on the demonstration of calcium oxalate in tissue sections. PMID- 4135798 TI - Autoclaving as an aid in the clearing of plant specimens. PMID- 4135799 TI - Sudan IV staining as a means of visualizing cleavage patterns in telolecithal eggs. PMID- 4135800 TI - Serial sectioning of Epon-embedded material for autoradiography. PMID- 4135801 TI - Thin-layer chromatography of lipids in adenovirus-treated human erythrocytes. PMID- 4135802 TI - [Changes in lysosomal enzyme activities of peritoneal leukocytes, serum and spleen in hens after lindane and DDT load]. PMID- 4135803 TI - [Changes in the biological activity of estrogens following the exposure of chickens to various insecticides of the chlorinated hydrocarbon series]. PMID- 4135804 TI - [Gambling addition. Depth psychology of the hand and handling]. PMID- 4135805 TI - Identification of nonfermentative gram-negative rods in clinical material. PMID- 4135807 TI - [Problems of follow-up care of patients with internal diseases and after operation in present day hospital service (author's transl)]. PMID- 4135806 TI - [Surgical correction of kinked internal carotid artery (author's transl)]. PMID- 4135808 TI - [A so-called open prostatectomy (author's transl)]. PMID- 4135809 TI - [Diagnostic value of vesiculography in histologically proven carcinoma of the prostate (author's transl)]. PMID- 4135810 TI - [Diagnosis of prostatic hypertrophy by means of cystourethrography (author's transl)]. PMID- 4135811 TI - Determination of plasma prothrombin with a reaction rate analyzer using a synthetic substrate. PMID- 4135812 TI - [The effects of cytostatic agents on short-term cultures (3H-uridine incorporation) and tissue cultures (cell counts) from human tumors (author's transl)]. PMID- 4135813 TI - [Psychological studies in the course of hypothyroidism]. PMID- 4135814 TI - [Stimultion of embryonic rat cells in culture by calf serum. 8. Specificity of serum factors S1 and S2 (author's transl)]. PMID- 4135815 TI - [Experimental transfer to the rabbit as a model of artificially induced placental insufficiency]. PMID- 4135816 TI - Antibodies with a gliotoxic effect in sera from rabbits injected with peptide 1 43 of the bovine encephalitogenic protein. PMID- 4135817 TI - Rotation cultures from different regions of embryonic chick brain. I. Biochemical and morphological characteristics. PMID- 4135818 TI - Effect of malnutrition on experimental allergic encephalomyelitis. PMID- 4135819 TI - Episodic encephalopathy associated with thyroid disorders. AB - Two patients with a thyroid disorder and an associated episodic encephalopathy are reported. The relationship between Hashimoto's thyroiditis, myxoedema, and neurological disease is considered, and the evidence for such disorders being due either to an underlying autoimmune process or that the encephalopathy is a direct result of the thyroid disorder is discussed. PMID- 4135821 TI - Comparative chromosome studies in Pinnipedia. PMID- 4135822 TI - Haploid meiosis as a regular phenomenon in the life cycle of Ulva mutabilis. PMID- 4135820 TI - Lymphocyte sensitization to basic protein of brain in multiple sclerosis and other neurological diseases. AB - The number of lymphocytes in the blood sensitized to encephalitogenic factor (EF) is less in multiple sclerosis than it is in general paralysis of the insane. The number appears related to the extent of parenchymatous destruction. The study offers no support for the view that lymphocyte sensitization to EF is of pathogenetic significance in multiple sclerosis. PMID- 4135823 TI - Prematurely condensed chromosomes of the Indian muntjac: a model system for the analysis of chromosome condensation and banding. PMID- 4135824 TI - Dicentric human X chromosomes. PMID- 4135825 TI - Chromosome banding pattern in a polymorphic population of Sorex araneus from northeastern Finland. PMID- 4135826 TI - Heterogeneity of Ph1 in chronic myeloid leukaemia. PMID- 4135827 TI - Localisation of repetitive DNA in mouse cells by in situ hybridization and dye binding techniques. PMID- 4135828 TI - Vacuolated villous epithelium of the small intestine of young pigs. PMID- 4135830 TI - [Lead in the ecological system along the express highway]. PMID- 4135829 TI - [Polychlorinated aromatic compounds as environmental poisons]. PMID- 4135831 TI - [Mandibular metastasis revealing a hepatoma]. PMID- 4135832 TI - Intracellular growth of an obligatory parasite mycobacterium leprae. Host bacterial interactions. PMID- 4135833 TI - [Analysis by titrimetry and electron microscopy of the molecular structure of lipoproteins, after enzymatic digestion]. PMID- 4135834 TI - [Clinical evaluation of tumor scanning with 57Co bleomycin]. PMID- 4135835 TI - Autoradiographic localization of intracellular alpha-foetoprotein in primary liver cancer in man. PMID- 4135836 TI - [Comparative studies on the histochemical behavior of amyloid, fibrinoid and hyalin deposits in blood vessel walls in mammals and birds. II. Carbohydrates]. PMID- 4135837 TI - Changes in the nervous system and musculature of old rats. PMID- 4135838 TI - A comparative morphological study of the developing node-paranode region in lumbar spinal roots. II. Light microscopy after osmiumtetroxide-alpha naphthylamine (OTAN)-staining. PMID- 4135839 TI - Indirect Wallerian degeneration in intramedullary root fibers of the kitten hypoglossal nerve light and electron microscopical observations on silver impregnated sections. PMID- 4135840 TI - Direct Wallerian degeneration in intramedullary root fibres of the kitten hypoglossal nerve light and electron microscopical observations on silver impregnated sections. PMID- 4135841 TI - Alpha-fetoprotein as a marker of embryo-specific differentiations in normal and tumor tissues. PMID- 4135842 TI - Alpha-fetoprotein: immunochemical purification and chemical properties. Expression in normal state and in malignant and non-malignant liver disease. PMID- 4135843 TI - [Sleep in patients with Parkinson's disease and its influence by L-DOPA (author's transl)]. PMID- 4135844 TI - Comparison of spectrophotometric and gas-liquid chromatographic measurements of serum diphenylhydantoin concentrations in epileptic out-patients. PMID- 4135845 TI - [Postoperative paralysis of the common peroneal nerve with fractures of the neck of the femur (author's transl)]. PMID- 4135846 TI - Phenytoin and folate deficiency: failure to show dose dependency. PMID- 4135848 TI - [Obturator nerve paralysis during parturition (author's transl)]. PMID- 4135847 TI - [Electrophysiological study of facial palsy in tetanus (author's transl)]. PMID- 4135849 TI - [Iodoproteinemia in various physiological and pathological conditions. Considerations on methods of determination]. PMID- 4135850 TI - [On the specificity of the complement-fixing antigen for Leptospira. Studies on syphilitic sera]. PMID- 4135851 TI - Improved techniques for staining and enumerating focus formation in viral infectivity assays. AB - Improved techniques consisting of glutaraldehyde fixation, Giemsa staining, and colony counter enumeration of foci in viral infectivity assays were compared to microscope scanning and lantern slide projection methods. These techniques broadened the scope of application to potentially hazardous viruses and increased the efficiency of assaying. PMID- 4135852 TI - The effect of cortisol on the phosphorylation of rat liver nuclear acidic proteins and the role of these proteins in biosynthesis of nuclear RNA. PMID- 4135853 TI - [Electrical activity of the diaphragm and a mechanical ventilator]. PMID- 4135854 TI - Influence of cardiotonic and cardioplegic agents on the heat production of the heart. PMID- 4135856 TI - [A mixture of gases as a bialveolar representation of ventilation]. PMID- 4135855 TI - [Accuracy of enzymatic quantitation of sorbitol in nanomolar quantities]. PMID- 4135857 TI - Effect of age and strain on uptake of alpha-amino-isobutyrate. PMID- 4135858 TI - Methods for determining the fraction of pulmonary surfactant lipid removed from the lung of beagle dogs by lavage. PMID- 4135859 TI - The kallikrein-kinin system in normal and glomerulonephritic rats. PMID- 4135860 TI - Glutamine-alpha-keto acid transaminase: partial purification and some properties of the enzyme from brain tissue. PMID- 4135862 TI - Activation of vestibular neurons during optokinetic nystagmus. PMID- 4135861 TI - Effect of angiotensin on renal function and intra-renal circulation. PMID- 4135863 TI - [Phase and amplitude distortions in electromagnetic measurements]. PMID- 4135864 TI - Release by isolated dog kidney of a natriuretic material following saline loading. PMID- 4135865 TI - Electrical noise and membrane transport processes. PMID- 4135866 TI - Interpretation of indicator-dilution curves as a local density random walk. PMID- 4135867 TI - Reliability of radioactive microspheres in regional blood flow measurements. PMID- 4135868 TI - Participation of baroreceptor reflexes in the perfused dog hind leg during electric stimulation of the hypothalamus. PMID- 4135869 TI - Effects of adrenalectomy and of neonatal sympathectomy in normotensive, renal hypertensive and spontaneously hypertensive rats. PMID- 4135870 TI - The relation between end-diastolic volume and source impedance of the left ventricle. PMID- 4135871 TI - Cross talk between right and left ventricle during the neonatal period. PMID- 4135872 TI - Correlation between electrophysiologic recordings and morphologic findings in the rabbit atrioventricular node. PMID- 4135873 TI - Assessment of myocardial contractility from intraventricular pressure recordings. PMID- 4135874 TI - Ion barriers in muscle fibres. PMID- 4135875 TI - [Effects of various expansions of conduction media on differences in electrocardiographic potentials gathered from cutaneous levels]. PMID- 4135876 TI - [Alinear end of respiratory and oxygen measurements of volume of expiration]. PMID- 4135877 TI - Persistence of an aldosterone influence on active sodium transport upon exposure of frog skin to ouabain. PMID- 4135878 TI - Quantitative studies of EEG development in the cerebral hemispheres of the chick embryo. PMID- 4135879 TI - Differentiation of foetal nervous tissue in tissue culture: morphology, electrophysiology and the effect of nerve growth factor. PMID- 4135880 TI - Histofluorimetric studies on 5-hydroxytryptamine in the pineal gland of the rat. PMID- 4135881 TI - Effect of free fatty acids on hepatic adenine nucleotide content and oxidative metabolism. PMID- 4135882 TI - Radioiodinated insulin fixation to a marine alga: Acetabularia mediterranea. PMID- 4135883 TI - Influence of saccadic eye movements on area 18 neurons in the cat. PMID- 4135884 TI - Interocular transfer, ocular dominance and "opposing habit" learning in the rabbit. PMID- 4135885 TI - The pressure-volume-flow relationship of the lung in healthy and ill neonates. PMID- 4135886 TI - Determination of O2-consumption, CO2-production and end-expiratory O2-and CO2 pressure in conscious dogs. PMID- 4135887 TI - Facilitated diffusion: the case of CO. PMID- 4135888 TI - The influence of changing physical load on aortic bloodflow. PMID- 4135889 TI - Influence of muscular exercise on the rates of uptake and oxidation of infused ketone bodies in normal man. PMID- 4135890 TI - The influence of an intensive period of training on a number of hematological parameters in male and female top athletes. PMID- 4135892 TI - Some psycho-physical experiments into the vertical dimension of occlusion of edentulous subjects. PMID- 4135891 TI - Neuronal firing in experimental hypercholesterolemia in rabbits. PMID- 4135893 TI - Morphologic aspects of the arterial wall in spontaneously hypertensive rats (SHR). PMID- 4135894 TI - Determination of the extracellular fluid volume with ferrocyanide as indicator. PMID- 4135895 TI - Reflex regulation of blood pressure and peripheral vascular tone during muscular contraction in the dog. PMID- 4135896 TI - Influence of heart rate on regional myocardial blood flow measured with radioactive microspheres in anaesthetized dogs. PMID- 4135897 TI - Effect of autoregulation on the intracortical distribution of renal blood flow. PMID- 4135898 TI - Cerebral blood flow measurements with 133 xenon during experimental metabolic alkalosis in the cat. PMID- 4135899 TI - The measurement of cerebral blood flow in the rat with radioactive microspheres. PMID- 4135900 TI - Influence of PCO2 on amino acids in the brain of the rat. PMID- 4135901 TI - [Use of triphenyltetrazolium chloride (TTC) for the determination of reduction activity of rumen liquor in clinically healthy cattle]. PMID- 4135902 TI - The primate globus pallidus: a Golgi and electron microscopic study. PMID- 4135903 TI - The primate substantia nigra: a Golgi and electron microscopic study. PMID- 4135904 TI - Quantitative determination of the alphafetoprotein (AFP). PMID- 4135905 TI - Serum gamma-globulins and hepatitis-associated antigen in blood donors, chronic liver disease and primary hepatoma. PMID- 4135906 TI - [Wermer's syndrome with endocrine tumors of the pancreas with a double cell component (apropos of 2 cases in the same family)]. PMID- 4135907 TI - Aggression and violence in children. PMID- 4135908 TI - Proceedings: A simple identification of osteoid matrix in decalcified bone. PMID- 4135909 TI - Cell wall protrusions induced by cauliflower mosaic virus in Chinese cabbage leaves: a cytochemical and autoradiographic study. PMID- 4135910 TI - Bleomycin, an inhibitor of vaccinia virus replication. PMID- 4135911 TI - A proposed nomenclature for the virion proteins of oncogenic RNA viruses. PMID- 4135912 TI - [Cytokinetic effect of bleomycin on mouse Ehrlich carcinoma in vivo. Possibilities of tumor cell synchronization for radiotherapy]. PMID- 4135913 TI - An epoxy resin embedding technique for large objects. PMID- 4135914 TI - Elastin V: syntheses, characterization, and staining properties of amidol black I. PMID- 4135915 TI - Combined enzymatic reaction for nervous and muscular tissues. PMID- 4135916 TI - A fluorescent brightener used for pollen tube identification in vivo. PMID- 4135917 TI - Basic Fuchsin-ferric chloride: a simplification of Weigert's resorcin-fuchsin stain for elastic fibres. PMID- 4135918 TI - Complete staining of neuromuscular innervation with bromoindigo and silver. PMID- 4135919 TI - Microwave irradiation as a generator of heat for histological fixation. PMID- 4135920 TI - Comparison of various oxidants for alum hematoxylin. PMID- 4135921 TI - A rapid method for in situ staining of prostatic and other tissue culture cells. PMID- 4135922 TI - A rapid thin-layer chromatographic system for Romanowsky blood stains. PMID- 4135923 TI - A modified toluidine blue staining method for nucleoli of ascites tumor cells. PMID- 4135924 TI - Distribution and configuration of surface myoneural junctions in the frog sartorius muscle. PMID- 4135925 TI - Identification of two populations of lymphocytes in rats and mice by routine transmission electron microscopy. PMID- 4135926 TI - Factors affecting the conversion of cross-reinnervated skeletal muscles. PMID- 4135927 TI - Primary liver cancer, alpha1 fetoprotein and hepatitis B antigen in Papua New Guinea. PMID- 4135928 TI - Pentobarbital-induced configurational changes at the synapse. PMID- 4135929 TI - Long term synaptic reorganization in rat fascia dentata deafferented at adolescent and adult stages: observations with the Timm method. PMID- 4135930 TI - Some serologic aspects of the immune response in the Atlantic bottle-nosed porpoise. PMID- 4135931 TI - Progestogens as contraceptives. PMID- 4135932 TI - Proceedings: Dynamics of transmissional ultrastructures in sympathetic neurones of the rat. PMID- 4135933 TI - Proceedings: The effect of electric stimulation on the axoplasmic transport of newly synthetized neuronal proteins. PMID- 4135934 TI - Proceedings: Some aspects of the release of the adrenergic transmitter. PMID- 4135935 TI - Proceedings: Pharmacology of the adrenergic mechanism. PMID- 4135936 TI - Dissociation between the chronotropic and inotropic actions of glucagon. PMID- 4135937 TI - Development and control of intestinal and hepatic fructokinase. PMID- 4135939 TI - [Neurologic follow-up studies of reanimated asphixia children]. PMID- 4135938 TI - [Alterations in serum proteins in patients with hypernephroma (author's transl)]. PMID- 4135940 TI - Intraluminal latex injection: an aid to the histological identification of renal tubules. PMID- 4135941 TI - The effect of fetuin and of spleen extract on hematopoietic precursors and on differentiated hematopoietic cells in irradiated mice. PMID- 4135942 TI - Detection of sialic acid containing compounds and the behaviour of gangliosides in polyacrylamide disc electrophoresis. PMID- 4135943 TI - Some quantitative aspects of the disc electrophoresis of ovalbumin using amido black 10B stain. PMID- 4135944 TI - Resolubilization of certain apoprotein components of human plasma high density lipoproteins in TCA-fixed polyacrylamide gels during destaining in acetic acid solutions. PMID- 4135945 TI - Comparison of the methylation of estradiol-17 beta and of estradiol-17 alpha by dimethyl sulfate. PMID- 4135946 TI - Assistance for the partially sighted child. PMID- 4135947 TI - [Aprindin, a new drug for the treatment of extrasystole. Studies at rest, after change of posture and during load]. PMID- 4135948 TI - Stimulation of glucose metabolism in rat mast cells by antigen, dextran and compound 48-80, used as histamine releasing agents. PMID- 4135949 TI - The thyroid gland morphology of cats subjected to hunger and thirst. PMID- 4135950 TI - Myelinated nerves of the rat iris. PMID- 4135951 TI - A method for the rapid elution of proteins from "mashed gel" after starch gel electrophoresis. PMID- 4135952 TI - A theory of precipitation and agglutination reactions in immunological systems. PMID- 4135953 TI - The relationship between cell viability and changes in mitochondrial ultrastructure, cellular ATP, ion and water content following injury of Ehrlich ascites tumor cells. PMID- 4135954 TI - Number of nuclei in isolated myocardial cells of pigs. PMID- 4135955 TI - [RNA synthesis during mitosis. I. Correlation between the condensation of chromosomes and the incorporation of 3H-uridine (author's transl)]. PMID- 4135956 TI - Changes in the nuclear structure during thyroid carcinogenesis in rats. An image analysis study. PMID- 4135957 TI - Hemoglobin Siam (alpha 2 15 arg beta 2): a new alpha-chain variant. PMID- 4135958 TI - Trisomy of the short arm of chromosome 17. PMID- 4135959 TI - Studies on the polymorphism of the soluble glutamic-pyruvic-transaminase in the population of Northern Bavaria (Germany). PMID- 4135960 TI - Case study of first course in teaching skills and methods for university medical staff. PMID- 4135961 TI - Self-instruction in general pathology by means of tape slide presentations. PMID- 4135962 TI - Review: The health care team. PMID- 4135963 TI - [Recent acquisitions on the etiopathogenesis of Whipple's disease. Report of a case with isolation of Klebsiella pneumoniae from the intestinal mucosa]. PMID- 4135964 TI - Photoallergy: a critical survey. PMID- 4135965 TI - [Editorial: Electron microscopy in diagnostic pathology]. PMID- 4135966 TI - [Effects of intravenous infusion of xylocaine on the extrasystole of chronic Chagasic cardiopathy]. PMID- 4135967 TI - Comparison of methods to detect significant bacteriuria. PMID- 4135968 TI - [Critical study and value of laboratory tests in the diagnosis of thyroid diseases]. PMID- 4135969 TI - [Simultaneous prostatic surgery and ureterolithotomy and their advantages]. PMID- 4135970 TI - A histological and histochemical study of the cotyledons of Phaseolus vulgaris L. during germination. PMID- 4135971 TI - Cataract extraction. PMID- 4135972 TI - [Prenatal sex-determination of the foetus without the use of amniocentesis (author's transl)]. PMID- 4135973 TI - [Comparative study of 2 methods of Mycobacterium tuberculosis discoloration. First results]. PMID- 4135974 TI - [Antibiotics in the therapy of Whipples disease (apropos of a case treated with tetracycline hydrochloride)]. PMID- 4135975 TI - [Study on albumins submitted to formaldehyde treatment and heated at 100 degrees C]. PMID- 4135976 TI - RNA-directed DNA polymerase--properties and functions in oncogenic RNA viruses and cells. PMID- 4135978 TI - Massive fibroid in the uterus. PMID- 4135977 TI - [Determination of 8 serum proteins in newborn infants with (physiological) transient jaundice]. PMID- 4135980 TI - Nursing care of the elderly lower-limb amputee. PMID- 4135979 TI - [Immunotherapy of cancer (some immunological problems in cancer therapy)]. PMID- 4135981 TI - Nursing care study. Above-knee amputation. PMID- 4135982 TI - Nursing care after primary excision. PMID- 4135984 TI - [Nursing care in pediatric surgery. 4. Surgical intervention on the infant's digestive tract and its nursing care]. PMID- 4135983 TI - [Nursing in pediatric surgery. 3. Children's cancer in the surgical field--solid tumor and its therapy]. PMID- 4135985 TI - [Nursing in pediatric surgery. 1. Diseases needing surgery in the neonatal period and their treatment]. PMID- 4135986 TI - [Current status of surgical treatment of esophageal cancer]. PMID- 4135987 TI - [The well-behaved child]. PMID- 4135988 TI - A state health education resource center. PMID- 4135989 TI - [Early experiences with Thiacetazone in Germany]. PMID- 4135990 TI - Spinal cord trauma. Experimental and clinical developments. PMID- 4135991 TI - Dynamic radioisotope study with a gamma camera-VTR system-RI angiography and CBF study in neurosurgical practice. PMID- 4135992 TI - Evoked cortical responses following stimulation of the thalamic VL nucleus in man. PMID- 4135993 TI - Growth control and adenosine 3':5'-cyclic monophosphate levels in clonal cells of rat glioma. PMID- 4135994 TI - Morphological and functional properties of pituitary adenomas in culture. PMID- 4135995 TI - Subtemporal transtentorial approach for large cerebello-pontine angle meningioma. PMID- 4135996 TI - Statistical analysis of chronic subdural hematoma in 309 adult cases. PMID- 4135997 TI - Chronic subdural hematoma in the aged. PMID- 4135998 TI - A case revealed prolonged cerebral vasospasm after evacuation of intracerebral hematoma. PMID- 4135999 TI - Services for the family. 2. PMID- 4136000 TI - [Early diagnosis of children with developmental disorders]. PMID- 4136001 TI - Eye enucleation. PMID- 4136002 TI - Better techniques for bagging stomas. 2. Colostomies. PMID- 4136003 TI - Scoliosis: affectionate yet firm postoperative nursing care. Nursing grand rounds. PMID- 4136004 TI - Chromosome preparation by air drying at low temperature and Giemsa banding procedures. PMID- 4136005 TI - Chiasma distribution at diakinesis in the normal human male. PMID- 4136006 TI - Cytological studies of the genus Rosa with special reference to the section Caninae. PMID- 4136007 TI - Repetitive DNA and constitutive heterochromatin in the chromosomes of guinea pig. PMID- 4136009 TI - C-banded male meiotic chromosomes of Acheta domesticus. PMID- 4136008 TI - Pericentric inversion Y in a population of newborn boys. PMID- 4136010 TI - How actinomycin binds to DNA. PMID- 4136011 TI - [Comparison of several different methods of antiblastic therapy in advanced carcinomas of the digestive system]. PMID- 4136012 TI - [Palliative treatment of cancer of the esophagus]. PMID- 4136013 TI - [Chemotherapy of hyperthyroidism and its remission in Japan]. PMID- 4136014 TI - [Evaluation of treatment of hyperthyroidism based on T3 analysis]. PMID- 4136015 TI - [Evaluation of effects of antithyroid drug treatment based mainly on the TRH test]. PMID- 4136016 TI - [Treatment of Basedow's disease in pregnancy with antithyroid drugs]. PMID- 4136017 TI - [Effect of inderal on external respiration in patients with hyperthyroidism]. PMID- 4136018 TI - Carriers and specificity in membranes. II. Characterization of carriers. Properties of ion-specific carriers. PMID- 4136019 TI - Binding studies of boron hydride derivatives to proteins for neutron capture therapy. PMID- 4136020 TI - Protein-binding polyhedral boranes. 1. PMID- 4136021 TI - The ultrastructure of plasma lipoproteins in lecithin:cholesterol acyltransferase deficiency. PMID- 4136022 TI - Effect of lysophosphatidyl choline on interaction between phosphatidyl choline and activator protein (apolipoprotein A-I) of lecithin:cholesterol acyltransferase. PMID- 4136023 TI - [The lymphoblastic transformation test in the presence of gamma globulins in rheumatoid polyarthritis]. PMID- 4136024 TI - Traffic pollution. PMID- 4136025 TI - Carcinogenic air pollutants in the exhaust from a European car operating on various fuels. PMID- 4136026 TI - [Effect of lindane on certain immunological reactions of rats]. PMID- 4136027 TI - Growing points in leprosy research. 4. Recent advances in the chemotherapy of leprosy. PMID- 4136028 TI - [Comprehensive review: lead, an ubiquitous noxious agent]. PMID- 4136029 TI - Surgical management of hyperthyroidism: current indications and results. PMID- 4136030 TI - T3 toxicosis. PMID- 4136031 TI - [Cross resistance of tubercle bacilli to KM, VM, CPM, LVM and TUM. I. The sensitivity of human tubercle bacilli isolated from patients to the five antibiotics (author's transl)]. PMID- 4136032 TI - Absence of B- and T-cell markers on acute lymphoblastic leukaemic cells and persistence of the T-cell marker on mitogen-transformed T-lymphocytes. PMID- 4136034 TI - [Anesthetic infiltrations and section of the peripheral nerves in the palliative treatment of advanced ischemic syndromes of the lower limbs]. PMID- 4136033 TI - Malignant disease of the kidney. An appraisal of diagnosis and management. AB - The diverse systemic effects associated with malignant renal tumours are described. It is emphasized that their recognition is essential for the early diagnosis of the tumour and that many of these effects may be overlooked unless the clinician is alert to their significance. Many of these early diagnostic clues also have a prognostic value.Although the basic management of a patient with a renal tumour continues to be a nephrectomy, the importance of tumour staging in relation to radical surgery is emphasized. Adjuvant therapy by radiotherapy, drugs, or immunotherapy is described and evaluated. PMID- 4136035 TI - Inhibition of allergic reactions by a novel phenanthroline ICI 74,917. PMID- 4136036 TI - Restricted clonal response to DNP in adult offspring of immunized mice: a maternal effect. PMID- 4136037 TI - Allotypic markers on Fab fragments of mouse immunoglobulins. PMID- 4136038 TI - The use of protein-substituted nylon catheters for selective immunoadsorption in vivo. PMID- 4136039 TI - Isolation of mouse thymus-derived lymphocyte specific surface antigens. PMID- 4136040 TI - Immunologic reactions to haptens on autologous carriers. II. Induction of hapten specific tolerance and correlations between antibody response and antigen-driven cell proliferation in vitro. PMID- 4136041 TI - Immunologic reactions to haptens on autologous carriers. 3. Cell separation at the antigen-specific in vitro DNA synthetic response level. PMID- 4136042 TI - Effect of carrier priming on the distribution of anti-hapten antibodies between IgG1 and IgG2 isotypes in the hyperimmune guinea pig. PMID- 4136043 TI - Tumor-specific and allospecific immunogenicity of soluble extracts from chemically induced murine sarcomas. PMID- 4136044 TI - Recurrent experimental allergic encephalomyelitis in the Lewis rat. PMID- 4136045 TI - Letter: Serologic code models with respect to the action of allogeneic anti-theta and xenogeneic anti-mouse or rat brain sera on thymocytes and brain tissue. PMID- 4136046 TI - Double-blind trial comparing two dosage schedules of beclomethasone dipropionate aerosol in the treatment of chronic bronchial asthma. Preliminary report of the Brompton Hospital-Medical Research Council Collaborative Trial. PMID- 4136047 TI - Sodium and the renin-angiotensin system in essential hypertension and mineralocorticoid excess. PMID- 4136048 TI - Body-fluid volume in low-renin hypertension. PMID- 4136049 TI - Reproductive and endocrine function after surgical treatment of bilateral crytorchidism. PMID- 4136050 TI - Infections in iron deficiency and other types of anaemia in the tropics. PMID- 4136051 TI - Defect of renal tubular acidification with antibody to loop of Henle. PMID- 4136052 TI - Hyposplenism in ulcerative colitis. PMID- 4136053 TI - Renal abnormality of essential hypertension. PMID- 4136054 TI - Editorial: Iron and resistance to infection. PMID- 4136055 TI - Editorial: The right to know. PMID- 4136056 TI - Editorial: Mumps vaccine. PMID- 4136057 TI - Editorial: Concern for quality. PMID- 4136058 TI - Editorial: Transoceanic schizophrenia. PMID- 4136059 TI - Vaccination in the control of influenza. Interim report to the Director of the Public Health Laboratory Service on a Collaborative Study with the Post Office. PMID- 4136061 TI - Planning in district management. Use of a teaching game. PMID- 4136060 TI - Serum-alpha 1-fetoprotein in hepatocellular carcinoma. PMID- 4136062 TI - Letter: The bran hypothesis. PMID- 4136063 TI - Letter: Yellow fat and visceral malignancy. PMID- 4136064 TI - Letter: Recurrent varicella-like illness in a child with leukaemia. PMID- 4136066 TI - Letter: HBAg carrier state in an infant delivered by caesarean section. PMID- 4136065 TI - Letter: Alcoholism among doctors. PMID- 4136067 TI - Letter: Serum hepatitis in late pregnancy. PMID- 4136068 TI - Letter: Cross-reaction of antibodies to human lactoferrin with HBAg. PMID- 4136069 TI - Letter: Detection of HBAg by passive haemagglutination. PMID- 4136070 TI - Letter: Prevention of post-transfusion hepatitis. PMID- 4136071 TI - Letter: False-positive results in antenatal diagnosis of neural-tube disorders. PMID- 4136072 TI - Letter: Rapid diagnosis of Down's syndrome. PMID- 4136073 TI - Letter: Transcervical fetoscopy. PMID- 4136074 TI - Letter: Klinefelter's syndrome in a fetus. PMID- 4136075 TI - Letter: Beta-trace protein and neural-tube defects. PMID- 4136076 TI - Letter: Neural-tube defects and subfertility. PMID- 4136077 TI - Letter: HL-A and infective sacroileitis. PMID- 4136078 TI - Letter: Offspring of chronic alcoholic women. PMID- 4136079 TI - Letter: Hepatomas and oral contraceptives. PMID- 4136081 TI - Letter: Geriatrics. PMID- 4136080 TI - Letter: Oral contraceptives and health. PMID- 4136082 TI - Letter: Diet and exercise in coronary heart-disease. PMID- 4136083 TI - Letter: Growth hormone and diabetic retinopathy. PMID- 4136084 TI - Letter: Plasma-catecholamines in sleeping hypertensives. PMID- 4136085 TI - Letter: Transfusion of fresh blood in the newborn. PMID- 4136087 TI - Letter: Body-temperature and myasthenia. PMID- 4136086 TI - Letter: Effects of feeding on blood-gases in a newborn infant. PMID- 4136088 TI - Letter: Hypotensive effect of angiotensin-converting-enzyme inhibitor SQ 20,881. PMID- 4136089 TI - Letter: What are we playing at? PMID- 4136090 TI - Letter: Cadaver kidney donation. PMID- 4136091 TI - Letter: Teaching biochemistry to medicals. PMID- 4136092 TI - Letter: Occupational hazards of businessmen in West Africa. PMID- 4136093 TI - Letter: Viruses in gastroenteritis. PMID- 4136094 TI - Letter: Intermittent compression: a new principle in treatment of wounds? PMID- 4136095 TI - Letter: Dimethylformamide: a cause of acute pancreatitis? PMID- 4136096 TI - Letter: Tuberculosis of the spine. PMID- 4136097 TI - Letter: Unusual tubular structures in brain reticulum-cell sarcoma. PMID- 4136098 TI - Letter: Reverse transcriptase in plasma of patients with breast cancer. PMID- 4136099 TI - Letter: Skin wrinkling in cystic fibrosis. PMID- 4136100 TI - Letter: A fashionable boot syndrome? PMID- 4136101 TI - Letter: Potential laboratory hazard from vacuum tubes. PMID- 4136102 TI - Letter: Breast tumours and hirsutism. PMID- 4136103 TI - Letter: 1,25-Dihydroxycholecalciferol and 1 alpha-hydroxycholecalciferol in hypoparathyroidism. PMID- 4136104 TI - Letter: Brain-levels of monoamine oxidase in depression. PMID- 4136105 TI - Heterogeneity of rat brain mitochondrial monoamine oxidase. PMID- 4136106 TI - [Progressive myoclonic epilepsy]. PMID- 4136107 TI - The relief of dysphagia by Celestin tube. PMID- 4136108 TI - [Identification of Paracoccidioides brasiliensis in infected tissues]. PMID- 4136109 TI - [A semiquantitative determination of vitamin D in horse and swine blood serum]. PMID- 4136110 TI - Clinical use of bleomycin: two case reports and review of toxicity. PMID- 4136111 TI - Immunoglobulin deficiency disorders. PMID- 4136112 TI - [Results of treatment of advanced cancers of the breast by intrapituitary implantation of radioactive yttrium]. PMID- 4136113 TI - Automatic conversion of slide synchronizing pulses on audio tape. PMID- 4136114 TI - [Minimal cerebral dysfunction]. PMID- 4136116 TI - Audiovisual production in a department of medical communications. PMID- 4136115 TI - [Histochemistry of human duodenal mucous membrane]. PMID- 4136117 TI - Light and electron microscopic studies on the cytochrome c adjective reaction for the demonstration of acid mucopolysaccharide. PMID- 4136118 TI - Initial surgical management of renal failure. PMID- 4136119 TI - [Educational aid]. PMID- 4136120 TI - [Audiovisual aid as a motivational means and a help in instruction in preventive dentistry]. PMID- 4136121 TI - Educating the patient who won't read. PMID- 4136122 TI - [Shoulder-hand syndrome in patients with hemiplegia]. PMID- 4136123 TI - [The product "Essentiale" in therapy of acute epidemic hepatitis]. PMID- 4136124 TI - [The criterion of the histamino-agglutinating factor and etiological classification of asthma patients]. PMID- 4136125 TI - [Ventricular parasystole in normal persons]. PMID- 4136126 TI - [Serum alpha-1-fetoprotein (AFP) in the immunological diagnosis of primary hepatoma]. PMID- 4136127 TI - [Immunoelectrophoretic analysis of serum gamma globulins in chronic hepatitis and hepatic cirrhosis]. PMID- 4136128 TI - Antigammaglobulin antibodies in rheumatic fever. PMID- 4136129 TI - [A histochemical study of carious lesions after staining with Mager, McNary and Lionetti's method]. PMID- 4136130 TI - Monoaminergic influence on testosterone-activated copulatory behavior in the castrated male rat. PMID- 4136132 TI - [Activities in a surgical room of a polyclinic]. PMID- 4136131 TI - Copulatory behavior in the male rat after impaired monoaminergic neurotransmission. PMID- 4136133 TI - Use of video-tape to change behavior. PMID- 4136134 TI - [Results of the treatment of acute staphylococcal destruction of the lung in children]. PMID- 4136135 TI - The variants of the group-specific component. A review of their distribution in human populations. PMID- 4136136 TI - Ovalbumin mRNA, complementary DNA and hormone regulation in chick oviduct. PMID- 4136137 TI - [Surgical treatment of intestinal obstruction caused by colonic cancer]. PMID- 4136138 TI - [Effect of pyocyanic infection on wound healing in experimental animals]. PMID- 4136139 TI - [Percival Bailey, born 9.5.1892, died 10.8.1973]. PMID- 4136140 TI - A reappraisal of the value of the EEG in subdural haematoma. A report on 86 patients, with a follow-up study. PMID- 4136141 TI - Renin release and renin-substrate reaction in the isolated perfused rabbit kidney. PMID- 4136142 TI - Errors in DNA replication as a basis of malignant changes. PMID- 4136143 TI - Long-incubation post-transfusion hepatitis without serological evidence of exposure to hepatitis-B virus. PMID- 4136144 TI - Relation between Escherichia coli K1 capsular polysaccharide antigen and clinical outcome in neonatal meningitis. PMID- 4136146 TI - Maternal enzymes of galactose metabolism and the "inexplicable" infantile cataract. PMID- 4136147 TI - Editorial: Micrococci in urine. PMID- 4136145 TI - Clinical, bacteriological, and immunological characterisation of ampicillin resistant Haemophilus influenzae type B. PMID- 4136148 TI - Undergraduate training in occupational medicine. PMID- 4136149 TI - Letter: Inhibition of labour by prostaglandin antagonists in impending abortion and preterm and term labour. PMID- 4136150 TI - Maurice Benjamin Strauss. PMID- 4136151 TI - Fibrinolytic inhibitors in human retroplacental blood. PMID- 4136152 TI - Letter: Diagnosing Corynebacterium vaginale (Haemophilus vaginalis) by means of wet mounts and direct stained smears. PMID- 4136153 TI - Common antigenic structures of HL-A antigens. II. Small fragments derived from papain-solubilized HL-A antigen molecules. PMID- 4136154 TI - Comparative inhibitory action of D- and L-tryptophan on the effect of d-lysergic acid diethylamide in vitro. PMID- 4136155 TI - [Histological examination of the arterial system originating from the aortic adventitia in experimental atherosclerosis]. PMID- 4136156 TI - [Resorcin-fuchsin staining. II]. PMID- 4136157 TI - [Whipple's disease. Case report (author's transl)]. PMID- 4136158 TI - Growth-hormone dependence among human breast cancers. PMID- 4136159 TI - Editorial: Surgical training in the E.E.C. PMID- 4136160 TI - Letter: Mebendazole and hydatid cysts. PMID- 4136161 TI - Letter: Haematological effects of gallbladder disease. PMID- 4136162 TI - Letter: Vitamin E and oxygen consumption. PMID- 4136163 TI - Plasma TSH and serum T-4 levels in long-term follow-up of patients treated with 131-I for thyrotoxicosis. AB - In February 1972 58% of patients euthyroid after iodine-131 therapy given for thyrotoxicosis between 1954 and 1966 had a high plasma TSH (>7.4 muU/ml) and 42% a normal plasma TSH level. A group of 69 of the euthyroid patients with high plasma TSH levels (25.0+/-2.0 muU/ml) in 1972 were re-examined 15 and 24 months later. The mean plasma TSH in the 66 patients remaining euthyroid at 15 months was 22.6+/-1.8 muU/ml, while three patients had become hypothyroid. At 24 months 64 of the patients were still available for study, of whom 61 remained euthyroid with a mean plasma TSH of 21.6+/-2.0 muU/ml, and a further three had become hypothyroid.All of a group of 61 of the euthyroid patients with normal plasma TSH levels (4.0+/-0.2 muU/ml) in 1972 remained euthyroid at 24 months with a mean plasma TSH of 4.1+/-0.3 muU/ml, though the plasma TSH level had become slightly raised in three.The mean serum T-4 level in the euthyroid patients with a high plasma TSH was significantly lower, though still in the normal range, than that in the euthyroid patients with a normal plasma TSH both in 1972 and in 1974.Since no patient with a normal plasma TSH level after iodine-131 treatment six to 18 years earlier for thyrotoxicosis developed hypothyroidism over a two-year period, the follow-up of such patients need not be so rigorous as that of similarly treated euthyroid patients with raised plasma TSH levels in whom hypothyroidism developed at the rate of 5% per year. PMID- 4136164 TI - [Conventional and dual competitive binding analysis of thyroxine by the Thyropac 4 kit and its clinical evaluation]. PMID- 4136165 TI - Quantitative study of the histocompatibility antigens on the surface of normal and leukaemic cells in mice. II. Quantitative variation in the expression of various H-2 specificities on the lymphoid cells from the B10 coisogenic strains of mice and their hybrids. PMID- 4136166 TI - [The Waaler-Rose test with preserved red corpuscles and with latex particles coated with rabbit gamma globulin]. PMID- 4136167 TI - Polyovular Graafian follicles in a newborn kitten with a study of polyovuly in the cat. PMID- 4136168 TI - Contractile protein changes in the regenerating rat liver. PMID- 4136169 TI - Verification of the previously reported t(3p minus:17q plus) by G banding. PMID- 4136170 TI - [Diagnostic significance of the study of alpha-fetoprotein in liver cirrhosis and primary cancer of the liver]. PMID- 4136171 TI - [Effect of synthetic thyrotropin-releasing hormone (TRH) on pituitary TSH secretion in man with special reference to the evaluation for TRH treatment. I. Effect of single TRH administration on pituitary thyroid fenction in man (author's transl)]. PMID- 4136172 TI - Vaginal adenosis: detection by colposcopy and iodine staining. PMID- 4136173 TI - Toxicants occurring naturally in foods. PMID- 4136174 TI - A modified alcian blue-periodic acid Schiff stain for epoxy-embedded atherosclerotic arteries. PMID- 4136175 TI - Antigen-specific thymus cell factors in the genetic control of the immune response to poly-(tyrosyl, glutamyl)-poly-D, L-alanyl--poly-lysyl. AB - The genetic control of the antibody response to a synthetic polypeptide antigen designated poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys [(T, G)-A--L] has been studied in congenic high responder C3H.SW (H-2(b)) and low responder C3H/HeJ (H 2(k)) strains of mice. This response is controlled by the Ir-1 gene and is H-2 linked. The method employed was to study the ability of specifically primed or "educated" T cells of each strain to produce cooperative factors for (T, G)-A--L in vitro. Such factors have been shown to be capable of replacing the requirement for T cells in the thymus-dependent antibody response to (T, G)-A--L in vivo. The T-cell factors produced were tested for their ability to cooperate with B cells of either high or low responder origin by transfer together with bone marrow cells and (T, G)-A--L into heavily irradiated, syngeneic (for bone marrow donor) recipients. Direct anti-(T, G)-A--L plaque-forming cells were measured later in the spleens of the recipients. The results showed that (a) educated T cells of both high and low responder origin produced active cooperative factors to (T, G) A--L, and no differences between the strains in respect to production of T-cell factors could be demonstrated; and (b) such factors, whether of high or low responder origin, cooperated efficiently with B cells of high responder origin only, and hardly at all with B cells of low responder origin. The conclusion was drawn that the cellular difference between the two strains lies in the responsiveness of their B cells to specific signals or stimuli received from T cells. As far as could be discerned by the methods used, no T-cell defect existed in low responder mice and the expression of the controlling Ir-1 gene was solely at the level of the B cells in this case. PMID- 4136176 TI - Biopsy of the pancreas. PMID- 4136177 TI - Serum alpha2-globulins in breast carcinoma. PMID- 4136178 TI - Editorial: Chlamydia and genital infection. PMID- 4136179 TI - Letter: Mobile coronary care. PMID- 4136181 TI - [Incidence of penetrating heart injuries and their histological characteristics]. PMID- 4136180 TI - Norepinephrine-sensitive properties of C-6 astrocytoma cells. PMID- 4136182 TI - [Prevention of the recurrence of goiter. Surgical and medical aspects]. PMID- 4136183 TI - Antibody response of inbred mouse strains to ordered tetrapeptides of tyrosine and glutamic acid attached to multichain polyalanine or polyproline. Tyr-Tyr-Glu Glu is a major determinant of the random poly-(Tyr, Glu)-polyDLAla--polyLys. AB - Five inbred mouse strains which represent high and low responders to the random synthetic polypeptide poly(LTyr,LGlu)-polyDLAla--polyLLys, designated (T, G)-A- L, to which the immune response is controlled by an H-2-linked gene, were immunized with three ordered tetrapeptides composed of tyrosine and glutamic acid attached either to multichain poly-DL-alanine or to polyproline. Only one of the three antigenic determinants, namely tyrosyl-tyrosyl-glytamyl-glutamic acid (T-T G-G), resembled the random peptide (T, G) in the pattern of immune responses elicited against it, and in the cross-reactivity of the specific antibodies with (T, G)-A--L. The immune response pattern to the other two ordered tetrapeptides, T-G-T-G and G-T-T-G, was different from that obtained with (T, G)-A--L, and no cross-reactivity was detected between the antibodies provoked with these peptides and (T, G)-A--L. Thus, it is suggested that T-T-G-G is a major determinant in the random (T, G)-A--L. PMID- 4136185 TI - Editorial: A blood-lymphocyte test for cancer? PMID- 4136184 TI - [D-penicillamine induced lupus during the treatment of rheumatoid arthritis. Report of 2 cases and systematic immunologic study during the treatment]. PMID- 4136186 TI - Letter: Cytotoxic lymphocytes from normal donors. PMID- 4136187 TI - Charles Wilfred Lawson. PMID- 4136188 TI - [Eosinophilia--a consideration on its immunological background and the significance of eosinopoietin (Komiya) (author's transl)]. PMID- 4136189 TI - Adjuvant effect of birch pollen on antibody production. PMID- 4136190 TI - Structural aspects of histamine release in rat peritoneal mast cells. Effects of adenosine 5'-triphosphate and role of calcium. PMID- 4136191 TI - Immunoglobulin production in chicken Harderian glands. PMID- 4136192 TI - Identification in the thyroid of antithyroglobulin antibodies in the fibrous variant of Hashimoto's thyroiditis. PMID- 4136193 TI - [A system of necessary interdisciplinary cooperation in the continuous care of handicapped children]. PMID- 4136194 TI - [Letter: Gamma globulins in viral meningitis?]. PMID- 4136195 TI - [Reverse transcriptase and its hypothetical role in tumor etiology]. PMID- 4136196 TI - [Immunobiology of Burkitt's lymphoma and human leukemias]. PMID- 4136197 TI - [Lipotropic agents in the treatment of psoriasis]. PMID- 4136198 TI - Practical synovial fluid examination. PMID- 4136199 TI - Aqueous solutions of some basic dyes in the specific staining of acid hydrolysed DNA. PMID- 4136200 TI - Histochemical studies in stomatal apparatus of Phaseolus mungo Linn. 3. Localization of ascorbic acid and peroxidase and their functional significance. PMID- 4136201 TI - Metachromasia through uranyl-ions method for nucleic acids detection in the vegetal cell. PMID- 4136202 TI - [Evidence of the enzymatic formation of acetaldehyde during the reduction of alcohol in liver sections with a stain reaction with purpald (author's transl)]. PMID- 4136203 TI - Analysis of synaptic vesicles in F-type axon terminals. PMID- 4136204 TI - Effects of Rauscher leukaemia virus on the immune system in susceptible and resistant mouse strains. PMID- 4136205 TI - Serological studies on Pseudomonas aeruginosa O group lipopolysaccharides. PMID- 4136206 TI - Effects of chemotherapy on the evolution of schistosomiasis japonica in chimpanzees. PMID- 4136207 TI - Studies on the regulation of carbohydrate synthesis during growth and differentiation of Physarum polycephalum. I. Activity of UDPGpyrophosphorylase during spherulation. PMID- 4136208 TI - Staining and fixation of unsaturated membrane lipids by osmium tetroxide. Crystal structure of a model osmium(VI) di-ester. PMID- 4136209 TI - Prostaglandins and in vitro TSH-dependent iodide binding by rat thyroid glands. PMID- 4136210 TI - [Isolation, characterization and quantitative immunochemical determination of the steroid-binding beta-globulin]. PMID- 4136211 TI - Immunofluorescent identification of a human thymic specific antigen. PMID- 4136212 TI - Histochemistry and fine structure of endocrine cells in foetal lungs of the rabbit, mouse and guinea-pig. PMID- 4136214 TI - The innervation of Purkinje fibres in the atrium of the avian heart. PMID- 4136213 TI - Time course and subcellular distribution of the radioactivity in a synaptic terminal after supplying the perikaryon with labelled glutamic acid. PMID- 4136215 TI - [The effect of heparin on the incidence of arrhythmias after acute myocardial infarction (author's transl)]. PMID- 4136216 TI - Electronmicroscopic comparison of the acid-fast and non-acid-fast strain of Mycobacterium phlei. PMID- 4136217 TI - Demonstration of orderly arranged acidic groups in amyloid by alcian blue. PMID- 4136218 TI - Comment on the paper by Marshall and Horobin "Measurements of the Affinities of Basic and "Mordant" Dyes for Various Tissue Substrates". PMID- 4136219 TI - Studies on mouse liver urate oxidase. 3. Fine localization of urate oxidase in liver cells revealed by means of ultracryotomy-immunoferritin method. PMID- 4136220 TI - Ultrastructural differences in cell membranes of erythrocytes myeloid and lymphoid cells as shown by topo-optical reactions. PMID- 4136221 TI - [Age related staining pattern of acid mucopolysaccharides in human rib cartilage by alcianblue-acridinorange following different fixation methods (author's transl)]. PMID- 4136222 TI - Organization of human mitotic chromosomes. PMID- 4136223 TI - Antiprotease activity in tears and nasal secretions. PMID- 4136224 TI - [Immunologic diagnosis of gastrointestinal cancer]. PMID- 4136225 TI - The structure of human high density lipoprotein and the levels of apolipoprotein A-I in plasma as determined by radioimmunoassay. AB - The major apoprotein of high density lipoprotein is apolipoprotein A-I (ApoA-I). In addition to being a structural component of this class of lipoproteins, ApoA-I also has a physiologic role as an activator of lecithin-cholesterol acyl transferase, an enzyme important in the metabolism of all lipoproteins. To measure ApoA-I content in human plasma, to assess its immunologic activity in hyperlipoproteinemia, and to carry out certain structural studies of high density lipoproteins, we have developed a double antibody radioimmunoassay. ApoA-I, isolated by gel filtration, was used to produce monospecific antisera. ApoA-I was iodinated by chloramine-T and the resulting [(125)I]-ApoA-I was purified by gel filtration. > 85% of [(125)I]-ApoA-I was precipitated by antibody, and 90% of bound [(125)I]ApoA-I was displaced by "cold" ApoA-I. Other lipoproteins and apoproteins did not react. Plasma and high density lipoprotein from normals and subjects with hyperlipoproteinemia displaced counts in parallel with ApoA-I, suggesting that the same antigenic determinants were reacting with antibody on lipid-free and lipid-associated ApoA-I. However, less than 5% of ApoA-I of high density lipoprotein reacted in the assay. Removal of the lipid by extraction increased the reactivity of ApoA-I in high density lipoprotein 15-20-fold; thus more than 95% of the ApoA-I molecules in "intact" high density lipoprotein are unreactive with antibody. Normal and hyperlipoproteinemic plasma and high density lipoproteins isolated from the same subjects continued to display parallelism with ApoA-I standard after lipid extraction, suggesting that ApoA-I of normal and hyperliproteinemic subjects are immunologically identical. About 90% of ApoA-I was in the d 1.063-1.21 fractions of normal plasma, trace quantities were found in the lipoproteins of d < 1.063, and the rest (about 10%) was in the d > 1.21 fraction. Normal plasma levels, assessed in extracted plasmas with a precision of 8%, were 100+/-35 mg/dl. Levels were normal in small groups of subjects with types II and IV hyperlipoproteinemia and high in pregnancy. However, larger population studies need to be performed to determine the distribution of ApoA-I levels in the various hyperlipoproteinemias. PMID- 4136226 TI - Abnormalities of chemotactic lymphokine synthesis and mononuclear leukocyte chemotaxis in Wiskott-Aldrich syndrome. AB - Wiskott-Aldrich syndrome is characterized by numerous humoral and cellular immune abnormalities including anergy, defective antibody production, and increased immunoglobulin synthesis. To define better the mechanisms of defective cellular immunity in this disorder, lymphoproliferative responses, lymphokine production, and the chemotactic responsiveness of mononuclear leukocytes (MNL) from patients with Wiskott-Aldrich syndrome were quantitated. Peripheral blood lymphocytes from these patients produced normal amounts of a lymphocyte-derived chemotactic factor (LDCF); however, their lymphoproliferative responses were frequently depressed, particularly to antigenic stimuli. In the absence of exogenous antigens or mitogens, lymphocytes from patients with Wiskott-Aldrich syndrome produced significantly more LDCF than unstimulated normal lymphocytes. In fact, this unstimulated LDCF production frequently approached the level produced by normal cells only after antigen or mitogen stimulation. The chemotactic responsiveness of MNL from Wiskott-Aldrich syndrome patients was impaired, particularly in those patients with the highest rates of unstimulated LDCF production. Furthermore, normal MNL chemotactic responsiveness could be impaired by preincubation of these cells in either LDCF or plasma from Wiskott-Aldrich syndrome patients. These observations suggest that the regulation of LDCF synthesis is abnormal in Wiskott Aldrich syndrome, and that a humoral chemotactic inhibitor, perhaps LDCF, "deactivates" the circulating MNL of patients with this syndrome. PMID- 4136228 TI - Enhancement of amphetamine action after interruption of ascending serotonergic pathways. PMID- 4136227 TI - Thyroid-stimulating activity and chorionic gonadotropin. AB - The nature of the substance with thyroid-stimulating activity (TSA) present in human chorionic gonadotropin (hCG) prepared from pregnancy urine was investigated. In the mouse thyrotropin bioassay, the characteristic maximum of blood radioactivity obtained with the TSA in hCG preparations occurred after that obtained with pituitary thyrotropin (hTSH) but before that obtained with long acting thyroid stimulator. Antiserum to the alpha subunit of hCG produced significant neutralization of the TSA in hCG. Significant antagonism of hTSH biologic activity was achieved with certain doses of hCG, suggesting that the TSA in hCG was a partial agonist of hTSH. This antagonism was neutralized by antiserum to the beta subunit of hCG. These immunologic results suggest that the substance with TSA in hCG preparations contains antigenic determinants similar to those of both the alpha and the beta subunit of hCG. Amounts of highly purified hCG and crude commercial hCG of equal immunologic activity were biologically indistinguishable in the bioassay for TSA. Both hCG immunoreactivity and the TSA in hCG adsorbed to concanavalin A and eluted with 0.2 M methyl alpha-D glucopyranoside. These results are consistent with the hypothesis that TSA is an intrinsic property of hCG or of a glycoprotein molecule physicochemically, biologically, and immunologically similar to hCG. PMID- 4136229 TI - Electron microscopy study of reovirus reaction cores. AB - A combined staining and shadowing method has been used to enhance the contrast of both reovirus cores and the RNA product that they have synthesized. After limited synthesis when all RNA strands associated with the core are nascent, many cores are observed that have more than 10 strands associated with each particle. The lengths of individual nascent mRNA molecules are not identical: many strands are extruded in the form of loops. These observations are consistent with the notion that synthesis of individual mRNA molecules occurs simultaneously at different rates at a number of different sites. The sites of extrusion are probably the 12 hollow projections located on the surface of the core. PMID- 4136231 TI - [Practolol in cardiac arrhythmias]. PMID- 4136230 TI - Properties of feline leukemia virus. I. Chromatographic separation and analysis of the polypeptides. AB - Rickard's strain of feline leukemia virus (FeLV) contains two large glycoproteins and five smaller polypeptides of molecular weights 100,000 (gp >/= 100), 70,000 (gp70), 30,000 (p30), 21,000 (p21), 15,000 (p15), 11,200 (p11), and 10,000 (p10) when chromatographed on 6% agarose in the presence of 6 M guanidine hydrochloride (GuHCl). P21 is a minor component which was not previously described for mammalian leukemia-sarcoma viruses and may be analogous to the seventh protein found in avian viruses. Analysis on 4% agarose and by sodium dodecyl sulfate polyacrylamide gel electrophoresis revealed that gp >/= 100 is actually >/= 200,000 daltons and dissociates to polypeptides of approximately 100,000 to 115,000 daltons, whereas gp70 can be resolved into six stained bands ranging from 40,000 to 80,000 daltons despite being rechromatographed as a single symmetrical peak on 6% agarose. Rechromatography on 8% agarose was found to be more effective than on 6% agarose or sodium dodecyl sulfate polyacrylamide gel electrophoresis for obtaining the five small polypeptides, especially p11 and p10, in a highly purified form suitable for further analysis and for obtaining more precise estimates of their molecular weights, especially when done by co-chromatography with iodinated standard proteins markers. Rechromatographed p30, p21, p15, p11, and p10 had molecular weights of 27,000, 18,000, 15,000, 12,000, and 12,000 respectively, by co-electrophoresis with the marker proteins on sodium dodecyl sulfate polyacrylamide gel electrophoresis, clearly establishing that the latter two FeLV polypeptides comigrate to form one less band when compared to elution from agarose. The isoelectric points of p30 and p15 were 5.5 and 8.9, respectively, after renaturation from GuHCl and 5.6 and 8.7, respectively, when isolated from Tween-ether treated virus. Rechromatographed p30, p15, and p11, renatured by removing GuHCl with dialysis, reacted only with their homologous antisera in immunodiffusion analysis, indicating that they are immunologically unrelated. Also the interspecies gs-3 determinant associated with p30 could be regained by removal of GuHCl. PMID- 4136232 TI - Charting a way through the wards. PMID- 4136233 TI - Diabetes mellitus, carcinoma of both breast. Nursing care study. PMID- 4136234 TI - Checking a plaster--how and why. PMID- 4136240 TI - [Effect of beta radiation on the regeneration of interrupted corneal nerves. I. Vital staining with methylene blue (author's transl)]. PMID- 4136241 TI - [Iatrogenic algodystrophy caused by phenobarbitone]. PMID- 4136242 TI - Binding of folic acid to serum proteins. 3. The effect of pernicious anaemia. PMID- 4136243 TI - The relevance of immune reactions in acute favism. PMID- 4136244 TI - The blood count during the ovarian cycle. PMID- 4136245 TI - Intraepithelial cervical neoplasia in women using intrauterine devices and long acting injectable progestogens as contraceptives. PMID- 4136246 TI - Esterase activity of Aspergillus niger in continuous culture. PMID- 4136247 TI - Comparison of serum vs eye bank storage of cat corneas. PMID- 4136248 TI - Experimental corneal wound strength. 7-0 Silk vs 10-0 monofilament nylon. PMID- 4136249 TI - Immunofluorescent detection of antibodies to ocular melanomas. PMID- 4136250 TI - [Serum and synovial levels of alpha-2-macroglobulin in the course of rheumatoid arthritis]. PMID- 4136251 TI - Osmium-zinc iodide staining and the quantitative study of central synapses. PMID- 4136253 TI - The role of the nervous system in regeneration, growth and cell differentiation in Hydra. I. Distribution of nerve elements during hypostomal regeneration. PMID- 4136254 TI - [Forced diuresis in the immediate postoperative period after prostatic adenomectomy]. PMID- 4136252 TI - The biochemical nature of the cell periphery of the salt gland secretory cells of fresh and salt water adapted mallard ducks. PMID- 4136257 TI - Radioimmunoassay of alpha-fetoprotein. I. Technique and serum levels in the normal adult. PMID- 4136258 TI - Radioimmunoassay of alpha-fetoprotein. II. Studies in patients suffering from hepatic diseases. PMID- 4136259 TI - G-band patterns, chromosomal homologies, and evolutionary relationships among wild sheep, goats, and aoudads (Mammalia, Artiodactyla). PMID- 4136260 TI - Observations on nucleolar staining with osmium tetroxide. PMID- 4136261 TI - Lysosomal function of juxtaglomerular granules. PMID- 4136262 TI - Lung inclusion bodies: different ultrastructure in simian and non-simian mammals. PMID- 4136263 TI - Some structural evidence in support of functional integration within the cephalic neuroendocrine complex of Periplaneta americana L. PMID- 4136264 TI - New antilymphoma L-asparaginase from Fusarium species. PMID- 4136265 TI - Frequency of 9qh+ and risk of chromosome aberrations in the progeny of individuals with 9qh+. PMID- 4136266 TI - Fluorescence banding pattern of human and mouse chromosomes with a benzimidazol derivative (Hoechst 33258). PMID- 4136267 TI - Othe relevance of non-histone proteins to the production of Giemsa banding patterns on chromosomes. PMID- 4136268 TI - The formation of the abnormal chromosome in balanced homologous Robertsonian translocation carriers. PMID- 4136269 TI - Familial short arm deletion of chromosome no. 15. PMID- 4136270 TI - Projections from the striate cortex to the diencephalon in the squirrel monkey (Saimiri sciureus). A light microscopic radioautographic study following intracortical injection of H3 leucine. PMID- 4136271 TI - Trypsin-banding procedure for avian chromosomes. PMID- 4136272 TI - [Possibilities and limits in the treatment of complicated heart defects in infants]. PMID- 4136273 TI - [Serologic diagnosis of measles]. PMID- 4136274 TI - Blocking of the effect of delta1 tetrahydrocannabinol (delta1THC) on spontaneous motor activity in the rat by immunization with a protein conjugate of delta1THC. PMID- 4136275 TI - Route of antigen administration for tolerance production. PMID- 4136276 TI - Destined for fame--but one would not think it. PMID- 4136277 TI - [Precipitation reaction for cancer and serum globulin determination in the differential diagnosis of pulmonary tuberculosis and lung neoplasms]. PMID- 4136278 TI - "Adolescent" cystinosis. A case presentation and review of the recent literature. PMID- 4136279 TI - "Generalized" epileptic seizures elicited by electrical stimulation of the frontal lobe in man. PMID- 4136280 TI - [A catechintrimer from oak bark (author's transl)]. PMID- 4136281 TI - [A clincial useful method for measuring nasal patency (author's transl)]. PMID- 4136282 TI - [A new histological staining: chromotropic silver hexamethylenetetramine. Its results in renal pathology]. PMID- 4136284 TI - [A study of 2 congenital hypothyroid goiters in siblings: identification of a genetic abnormality in thyroid hormonogenesis marked by the absence of thyroglobulin and by the iodination of unsuitable proteins rich in iodohistidine and deficient in thyroxine]. PMID- 4136283 TI - [A prospective study of impending myocardial infarct]. PMID- 4136285 TI - [Aberrant ventricular conduction in atrial premature beats and atrial pacing, studies with His bundle electrogram (author's transl)]. PMID- 4136286 TI - [About selection of suitable tetrazoliumsalts for quantitative estimation of enzymes in the histochemistry (author's transl)]. PMID- 4136287 TI - [Acaricide action of hexachlorano-creoline emulsions]. PMID- 4136288 TI - [Acquired granulocyte disorders]. PMID- 4136289 TI - [Actinomycins synthesized by Actinomyces sp. 2 strain in the presence of sulfadimezine]. PMID- 4136290 TI - [Advances in internal medicine. Present-day trends of studies of immune phenomena in rheumatoid arthritis]. PMID- 4136291 TI - [Agargel and immune electrophoretic investigations about the interaction of the stuff dye with the plasma proteins (author's transl)]. PMID- 4136292 TI - [Alcohol and neoplasms]. PMID- 4136293 TI - [Alkaloids from the Thai-drug Krung Kha Mao (Menispermaceae) 3. Isolation and identification of further bisbenzylisochinoline-alkaloids of the berbamine, resp. oxyacanthine-type (author's transl)]. PMID- 4136294 TI - [An electron-microscopic observation of tissue changes affected by anticancer agents. 2. Effects of bleomycin on the transplantable Vx-7 carcinoma of rabbits (author's transl)]. PMID- 4136295 TI - [Analog circuit for automated detection of the R on T-phenomenon (author's transl]. PMID- 4136296 TI - [Anthropologic significance of public and private antigens]. PMID- 4136297 TI - [Antistreptokinase activity in the newborn infant]. PMID- 4136298 TI - [Appearance and evolution of leukocyte antibodies in recipients of transfusions]. PMID- 4136300 TI - [Association between HLA antigens and beta-2 microglobulins detected by immunofluorescence on human lymphocyte membrane]. PMID- 4136299 TI - [Aspiration cytology in the diagnosis of palpable diseases of the breast (author's transl)]. PMID- 4136301 TI - [Audio-visual aids and the problem of instruction in dentistry]. PMID- 4136302 TI - [Basic encephalitogenic proteins: structure, immunologic activity and disintegrative changes]. PMID- 4136303 TI - [Behavior of liver mitochondria of fetal and newborn rats in isopycnic and gradient centrifugation in saccharose]. PMID- 4136304 TI - [Beta2-microblogulin in serums: a measure of glomerular filtration]. PMID- 4136305 TI - [Bicircadian periodicity in the sleep-wakefulness cycle under timeless conditions. Polygraphic study]. PMID- 4136306 TI - [Biochemical and ultrastructural correlation in the secretion of enzymatic proteins from the exocrine pancreas]. PMID- 4136307 TI - [Birefringence of a histological slice produced by irradiation with linearly polarized ultraviolet light (author's transl)]. PMID- 4136308 TI - [Bleomycin: cellular and vascular alteration in a patient (author's transl)]. PMID- 4136309 TI - [Capillary-nerve cell relationships in the intermuscular nerve plexus of the large intestine normally and after bilateral section of the pelvic nerves]. PMID- 4136310 TI - [Case of polymyalgia rheumatica]. PMID- 4136311 TI - [Case of A-G dysgammaglobulinemia]. PMID- 4136312 TI - [Chemotherapy of tumors. 3. Chemical review of natural antineoplastic agents: antibiotics and related compounds; enzymes and hormones]. PMID- 4136313 TI - [Chicken myoglobin: peptides obtained by thermolysin hydrolysis and complete structure]. PMID- 4136314 TI - [Cholinesterase and alpha-2-globulins of human serum]. PMID- 4136315 TI - [Clinical trial of an anticoagulant drug]. PMID- 4136316 TI - [Cobalt-57 labeled bleomycin metabolism in the mouse. 1. Distribution and Kinetics]. PMID- 4136317 TI - [Combined action of gibberellic acid and respiratory agents on oxygen consumption of storage plant tissue]. PMID- 4136318 TI - [Comparative statistics on complication rate in transurethral electroresections (TUR), cryotherapy and adenectomy of prostate]. PMID- 4136320 TI - [Comparative studies on the usefulness of the lymphocyte transformation test and the monocyte test in the diagnosis of allergies]. PMID- 4136319 TI - [Comparative studies on the pathology and pathogenesis of spontaneous coli enterotoxemia and of the experimental coli endotoxin syndrome in swine. V. Studies on the pathomorphology of the central nervous system in spontaneous coli enterotoxemia and the experimental coli endotoxin syndrome]. PMID- 4136321 TI - [Complications after thyroid gland surgery]. PMID- 4136322 TI - [Considerations relating to early development diagnosis]. PMID- 4136323 TI - [Constrained conformation imposed on polynucleotides by various types of sugar]. PMID- 4136324 TI - [Contemporary problems in physical medicine, functional rehabilitation, and rheumatology]. PMID- 4136325 TI - [Contribution to stigma cyto-physiology. V. Histochemical characterization of essentially lipidic nature of the Forsythia intermedia Z. exudate in photonic and electronic microscopy (author's transl)]. PMID- 4136326 TI - [Correlation between arrhythmias (author's transl)]. PMID- 4136327 TI - [Correlation between indices of thyroid I-131 absorption, basal metabolism, protein-bound iodine and various glycoprotein components in the blood serum in thyrotoxicosis]. PMID- 4136329 TI - [Cryogenic surgery of bladder-neck adenoma and of prostatic carcinoma]. PMID- 4136328 TI - [Correlation--analytical studies on plasma coagulation factors and various findings in patients with obstructive jaundice]. PMID- 4136330 TI - [Cutaneous biopsy in hyalin warts of the macula. Critical study of results]. PMID- 4136331 TI - [Cytochemical examination methods in the liquor-cytodiagnosis of neurologic diseases]. PMID- 4136332 TI - [Cytochemical study of the fetal rat pituitary gland]. PMID- 4136333 TI - [Decomposition of thioacetazone through ultraviolet radiation]. PMID- 4136334 TI - [Determination of anti-D activity in plasma pools and gamma globulins destined for Rh prevention]. PMID- 4136335 TI - [Determination of protein-bound iodine in cattle]. PMID- 4136336 TI - [Determination of proteins in plasma ultrafiltrates]. PMID- 4136337 TI - [Determination of thyroid function]. PMID- 4136338 TI - [Diagnosis of blood-brain barrier disorders and immunoreactive processes by cerebrospinal fluid electrophoresis]. PMID- 4136339 TI - [Diphtheria toxin: the molecular biology of an infection]. PMID- 4136340 TI - [Discrepancy between clinical status and in vitro thyroid function tests]. PMID- 4136341 TI - [Disseminated intravascular coagulation in blastic leukemia and certain other disorders]. PMID- 4136342 TI - [Do Pseudomonas aeruginosa develop chromogenic properties in connection with ion exchange resins?]. PMID- 4136343 TI - [Drug-induced hematologic disorders in Japan]. PMID- 4136345 TI - [Education and training in gastroenterological endoscopy--an educational program (author's transl)]. PMID- 4136344 TI - [Dysrhythmias in children after surgical closure of atrial septal defect (a series of 67 cases) (author's transl)]. PMID- 4136346 TI - [Effect of chlormadinone acetate on the incorporation of S-35 in fibroblasts of the human cervix in vitro]. PMID- 4136347 TI - [Effect of distamycin A and netropsin on normal cells and wall-less cells of Escherichia coli W 1655 F+]. PMID- 4136348 TI - [Effect of glycine residues on the conformation of oligopeptides]. PMID- 4136350 TI - [Effect of naproxen on DNA synthesis and DNA repair in human lymphocytes]. PMID- 4136349 TI - [Effect of imipramine on rat liver mitochondria]. PMID- 4136351 TI - [Effect of sulfadimezin on the biosynthesis of an actinomycin antibiotic by Actinomyces chrysomallus]. PMID- 4136352 TI - [Effect of thymectomy on adrenal glands. Opotherapy using thymus gland extracts]. PMID- 4136353 TI - [Effect of urea and malonamide on the cytotoxic action of alloantisera in the presence of complement]. PMID- 4136354 TI - [Electron microscopy studies on human pathogenic fungi. II. Ultrastructural changes of Candida albicans cells in the human vaginal epithelium under treatment with clotrimazol]. PMID- 4136355 TI - [Enzyme histochemical investigation on the papillar muscle of the heart of various mammals (author's transl)]. PMID- 4136359 TI - [Evidence of a polyadenylate segment in globin messenger RNA from the spleen of anemic rabbits]. PMID- 4136358 TI - [Evaluation of some chemical, culture and cytological tests in the bacteriological examination of urine]. PMID- 4136357 TI - [Epidemic keratoconjunctivitis]. PMID- 4136360 TI - [Exercise test and arrhythmia (author's transl)]. PMID- 4136356 TI - [Enzyme induction in the liver following administration of lindane by the oral route. A functional and morphological study in rats (author's transl)]. PMID- 4136363 TI - [Formation of recurrence and carcinoma following surgical removal of prostatic adenoma]. PMID- 4136362 TI - [Exsudative pleurisy in rheumatoid arthritis]. PMID- 4136361 TI - [Experimental xenografting in widely divergent species. Modification of the hyperacute xenogeneic rejection of kidneys from pigs (donor) by extreme hemodilution of dogs (recipients) (author's transl)]. PMID- 4136364 TI - [Further improvement of the ACD-AG preserving solution for blood. 1. Enhancement of the erythrocyte oxygen transport function by addition of pyruvate and xylite]. PMID- 4136365 TI - [Gaseous mixture as a monoalveolar model]. PMID- 4136366 TI - [Gene expression in ribosomal proteins of Escherichia coli]. PMID- 4136367 TI - [Genesis of jaw cysts based on comparative studies of cystic content and blood serum]. PMID- 4136368 TI - [Goiters in the newborn]. PMID- 4136369 TI - [Heat stability of rabbit, rat, and mouse erythrocytes in vitro and their survival in the organism]. PMID- 4136370 TI - [Hemodynamic consequences of cardiac arrhythmias. With special reference to premature beats and atrial fibrillation (author's transl)]. PMID- 4136371 TI - [Histochemical and ultrastructural studies of a casus of alpha-chain disease (author's transl)]. PMID- 4136372 TI - [Histochemical determination of acid mucopolysaccharides in the sclera]. PMID- 4136373 TI - [Histoenzymological study of the intestinal mucosa in 5 cases of Whipple's disease. Development under antibiotic treatment]. PMID- 4136374 TI - [Histopathological study of macular drusen]. PMID- 4136376 TI - [Identification of blood stains from newborns or fetuses by means of alpha1 fetoprotein-precipitation (author's transl)]. PMID- 4136375 TI - [Human serum albumin incompatibility: clinical and immunological investigations (author's transl)]. PMID- 4136377 TI - [Identification of the XYY syndrome by quinacrine dihydrochloride fluorescence staining]. PMID- 4136378 TI - [Immunocytological localization of MSH activity in the meta-adenohypophyse of stickleback fish Gasterosteus aculeatus L]. PMID- 4136379 TI - [In vitro maturation of the final precursor of Coxsackie virus]. PMID- 4136380 TI - [In vitro study of the pharmacological activity of disodium cromoglycate]. PMID- 4136381 TI - [In vivo behavior of lymphocytes in patients with chronic lymphadenosis under the effect of anti-lymphadenosis gamma globulin]. PMID- 4136382 TI - [Incorporation of adenosine and adenine in isolated rabbit heart]. PMID- 4136383 TI - [Increased concentration of phytanic acid in plasma and liver of an infant with cerebral damage of unknown etiology (author's transl)]. PMID- 4136384 TI - [Indirect induction of temperate bacteriophate Mu-1]. PMID- 4136385 TI - [Infection by varicella-zoster virus during pregnancy (author's transl)]. PMID- 4136386 TI - [Infectivity of the DNA extracted from purified nuclei of non-permissive Rous sarcoma cells]. PMID- 4136387 TI - [Influence of chlormadinonacetate on the rat ovary (author's transl)]. PMID- 4136388 TI - [Influence of hormonal contraceptives on the occurrence of vaginal mycoses]. PMID- 4136389 TI - [Inhibition of the multiplication of Paramyxovirus Parainfluenzae 3 strain EA 102 by actinomycin D]. PMID- 4136390 TI - [Interaction of atropine with blood serum proteins]. PMID- 4136391 TI - [Interaction of gastrointestinal hormones with pancreatic cells in the rat]. PMID- 4136392 TI - [Intraportal injection chemotherapy and fluctuation of alpha 1-fetoprotein in a patient with metastatic liver cancer originating at the stomach]. PMID- 4136393 TI - [Karyometric findings on the zona fasciculata of the adrenal gland following antithyroid medication in the embryologic animal experiment]. PMID- 4136395 TI - [Letter: Bleaching of Gram preparations]. PMID- 4136394 TI - [Kinetics of non-activated euglobulin fibrinolysis in human plasma]. PMID- 4136396 TI - [Letter: Gammaglobulin in pregnant women in contact with rubella]. PMID- 4136397 TI - [Letter: In-vitro diagnosis of thyroid gland function]. PMID- 4136398 TI - [Leukocytes and erythrocyte GPD deficiency]. PMID- 4136399 TI - [Limitation of the vascular effects of noradrenaline using noradrenaline itself]. PMID- 4136400 TI - [Luminescence of the partitions in Fusarium species]. PMID- 4136402 TI - [Membrane proteins. I. Chemical modification of tyrosyl residues]. PMID- 4136401 TI - [Mechanisms of immunologic facilitation studied in vitro. The action site of facilitating antibodies in mixed lymphocyte culture]. PMID- 4136403 TI - [Metabolism of bleomycin labled with a divalent cation. 2. Study of urinary metabolites in the rat and comparative study of tissue elimination of the cation alone or chelated by bleomycin]. PMID- 4136404 TI - [Metabolism of dopamine and norepinephrine in rat brain after acute and chronic administration of haloperidol, loxapine and clozapine]. PMID- 4136405 TI - [Microcomplement fixation test applied to a diphtheria toxin-antitoxin system]. PMID- 4136406 TI - [Morphological, cytochemical and autoradiographic studies on lymphocyte cultures with the addition of phytohemagglutinin or tuberculin]. PMID- 4136407 TI - [Morphology of benign localized pleural-mesothelioma]. PMID- 4136408 TI - [Myxedema due to lithium. Clinical and physiopathological study apropos of 2 cases]. PMID- 4136409 TI - [Neamine resistance: identification of two loci on the bacterial chromosome]. PMID- 4136410 TI - [New aspects of the action and use of antireticular cytotoxic serum]. PMID- 4136411 TI - [Nose rinsing, gargling and steambaths]. PMID- 4136412 TI - [Nursing of a patient with empyema treated with permanent surgical closure of the main bronchus]. PMID- 4136413 TI - [On the histochemical demonstration of zinc in the epididymis of humans (author's transl)]. PMID- 4136414 TI - [Osteoporosis caused by digestive disorders with rheumatic symptoms]. PMID- 4136415 TI - [Parathyroid scintigraphy]. PMID- 4136416 TI - [Physiological studies on the anti-thrombin system]. PMID- 4136417 TI - [Polycylic aromatics in surface and ground water]. PMID- 4136418 TI - [Practical aspects of the isolation of lymphocytes and granulocytes from blood]. PMID- 4136419 TI - [Practical hints on transurethral electroresection of prostatic adenoma. Experience in 500 cases]. PMID- 4136421 TI - [Prevention of viral hepatitis]. PMID- 4136420 TI - [Presence of sequences rich in polyadenylic acid in the RNA of a higher plant: Zea mays]. PMID- 4136423 TI - [Procedure to follow in the presence of major arrhythmias. Spike torsades]. PMID- 4136422 TI - [Primary bullous lung disease]. PMID- 4136424 TI - [Prognosis of inoperable bronchial carcinomas managed through a combination of cytostatic- and radiotherapy]. PMID- 4136425 TI - [Purification of encephalitogenic basic protein of sheep brain]. PMID- 4136426 TI - [Radiotherapy of tumors in childhood]. PMID- 4136427 TI - [Removal of infected dentin using fuchsin staining as a guide. 1. Experiment with extracted carious teeth (author's transl)]. PMID- 4136428 TI - [Results in the surgery of gastric carcinoma. Own results]. PMID- 4136429 TI - [Results of the treatment of corneo-conjunctival infections with Didrosulfon]. PMID- 4136430 TI - [Results related to the use of a new antihemorrhoidal preparation in the treatment of the ano-rectal varicose syndrome in pregnancy and the puerperium]. PMID- 4136431 TI - [Rhinomanometric tests of the effect of nasivinettes in normal subjects (author's transl)]. PMID- 4136432 TI - [Round-table conference on harmful effects of smoking. A synopsis of a round table conference held during the XXVth Congress of the Polish Society for Internal Medicine (Katowice, 20-22 September, 1973)]. PMID- 4136433 TI - [Selection of thermosensitive mutants in the streptomycin region of the Escherichia coli chromosome]. PMID- 4136434 TI - [Selective induction of a liver microsomal mixed-function oxygenase system. I. Comparison of acetylamino-2-fluorene with acetylamino-4-fluorene]. PMID- 4136435 TI - [Selective induction of a liver microsomal mixed-function oxygenase system. II. Kinetic study of benz(a)pyrene hydroxylase]. PMID- 4136436 TI - [Selective transcription of phage RNA by revertase using "directed" primer]. PMID- 4136437 TI - [Semiquantitative histochemical investigations on the juxtaglomerular apparatus of the rein in the animal experiment (author's transl)]. PMID- 4136438 TI - [Separation of 2 different tumor antigen entities in 2 iso-antigenic variants obtained from a chemically induced tumor in F1(A. CA X A. BY) hybrids]. PMID- 4136439 TI - [Significance of mediastinoscopy in bronchial carcinoma]. PMID- 4136440 TI - [Skin and cardiovascular system]. PMID- 4136441 TI - [Skin capillaries in adult diabetes mellitus. Optical and electron microscopic study]. PMID- 4136442 TI - [Sleep patterns of workers on rotating shifts]. PMID- 4136443 TI - [Sporadic Refsum-Thiebaut disease in a family with 3 cases of ichthyosis simplex]. PMID- 4136444 TI - [Staining of corneal acid mucopolysaccharides in man an various species of animals]. PMID- 4136445 TI - [Sterilization of female Drosophila melanogaster using reserpine. Effect of concentration and study of ovarian function]. PMID- 4136446 TI - [Stimulation of cyclic AMP and cyclic GMP in rat pancreas stimulated by gastro intestinal hormones in vivo and in vitro]. PMID- 4136447 TI - [Study of the antigenic characteristics of the erythrocytes in the blood of susliks from the Volga valley according to the phytohemagglutination reaction]. PMID- 4136448 TI - [Study of the formation of granulations in the antehypophyseal prolactin cells, in the hedgehog (Erinaceus europeus L.)]. PMID- 4136449 TI - [Study of various microelements in prostatic adenomas]. PMID- 4136450 TI - [Substructures of the defective phages of 2 strains of Streptomyces melanochromogenes]. PMID- 4136451 TI - [Susceptibility of drug-resistant tubercle bacilli isolated from pulmonary tuberculosis in patients to paromomycin (Aminosidine) (author's transl)]. PMID- 4136452 TI - [Synthesis of antiglycan antibodies type IgM and IgG with limited heterogeneity]. PMID- 4136453 TI - [Technique of thyroid function diagnosis]. PMID- 4136454 TI - [The alpha 2-beta 1 bond in the electrophoretic pattern]. PMID- 4136455 TI - [The contamination of surface-, rain-, and drinking water with chlorinated hydrocarbons]. PMID- 4136456 TI - [The effect of adenine and guanosine on the survival rate of erythrocytes after storage at temperatures between 4 and 25 degrees centigrade]. PMID- 4136457 TI - [The effect of storage temperatures between 4 and 25 degrees centigrade on the usefulness of stored blood]. PMID- 4136458 TI - [The effects of amidination on erythrocytes]. PMID- 4136459 TI - [The epidemic of keratoconjunctivitis of the spring of 1973]. PMID- 4136460 TI - [The evidence of the succinodehydrogenase with dimethylsulphoxyd (DNSO)-addition in the cochlea of guinea pig (author's transl)]. PMID- 4136461 TI - [The fate with time of protein-bound 131-iodine in the budgerigar (Melopsittacus undulatus) with simultaneous measurement of activity in the liver and other organs]. PMID- 4136462 TI - [The hematotoxicity of thiamphenicol. 3. Light microscopal, electron microscopal and cytogenetic studies]. PMID- 4136463 TI - [The histochemical behaviour of the unspecific esterases in the liver and kidney opposite any inorganic and organic compounds--a contribution to the enzyme toxicology (author's transl)]. PMID- 4136464 TI - [The occurrence of chlorinated hydrocarbon insecticides in school meals in the GDR]. PMID- 4136465 TI - [The receptors in immunocompetent cells]. PMID- 4136466 TI - [The topochemistry of the NAD(P)H-NBT-reductase activity in the kidney of rabbit (author's transl)]. PMID- 4136467 TI - [The use of fibrinogen and thrombin for localized thrombosing of arteries]. PMID- 4136468 TI - [Therapeutic action of infrared and ultraviolet radiation on wound healing]. PMID- 4136469 TI - [Treatment of prostatic carcinoma]. PMID- 4136470 TI - [Treatment of respiratory failure with antithyroid drugs and radioactive iodine I 131]. PMID- 4136471 TI - [Ultrastructural location of T auto-antigen on the guinea pig spermatozoon]. PMID- 4136472 TI - [Unusual case of Hashimoto's disease in pluriglandular insufficiency]. PMID- 4136473 TI - [Unusual leukemic syndrome in a newborn with 21 trisomy: megakaryocyte and platelet proliferation; disseminated intravascular coagulation syndrome]. PMID- 4136474 TI - [Use of an antiphlogistic drug (Tanderil) in chronic bronchitis]. PMID- 4136475 TI - [Use of bleomycin in otorhinolaryngology. Apropos of 41 cases]. PMID- 4136476 TI - [Use of closed-circuit television and audio-visual aids in pre- and postgraduate teaching of internal medicine]. PMID- 4136477 TI - [Virus etiology of childhood leukemias (report) (author's transl)]. PMID- 4136479 TI - [2-cycle system of work organization and complex biochemical examination of patients at a laboratory of a district hospital]. PMID- 4136478 TI - [Visualization of myoepithelial cells in the bovine mammary gland and their behavior during the ejection of milk]. PMID- 4136480 TI - A bleomycin-inactivating enzyme in mouse liver. PMID- 4136481 TI - A carcinoid saga. PMID- 4136482 TI - A case of a girl with a 21 ring chromosome. PMID- 4136483 TI - A clinical study on 29 cases of debatable STS and TPI seroreactions in Greenland. PMID- 4136484 TI - A comparative evaluation of the treatment of hyperthyroidism. PMID- 4136485 TI - A comparative study of behavioural aspects in encopretic children. PMID- 4136486 TI - A double isotope technique for estimating insulin degradation in vivo. PMID- 4136487 TI - A familial, balanced 2-5 translocation associated with trisomy 21 in one individual. PMID- 4136488 TI - A method for obtaining ultrathin frozen sections from fresh or glutaraldehyde fixed tissues. PMID- 4136489 TI - A method for the determination of polycyclic hydrocarbons in air-borne particulates from urban and other atmospheres. PMID- 4136490 TI - A method for the quantitative estimation of blood-brain barrier (BBB) damage. PMID- 4136491 TI - A new temporary pacing catheter with improved sensing and safety characteristics. PMID- 4136492 TI - A patient with prostatectomy. PMID- 4136493 TI - A procedure for selective acid extraction, staining and quantitative measurement of histones in Allium root nuclei. PMID- 4136494 TI - A rapid, new method for quantitative analysis of human amylase isozymes. PMID- 4136495 TI - A safer method of dilating oesophageal strictures. PMID- 4136496 TI - A serological tool for the diagnostics of virus B hepatitis. PMID- 4136497 TI - A simple visual pattern stimulator. PMID- 4136498 TI - A sliced gel assay for some enzymes which utilize guanine as substrate. PMID- 4136499 TI - A staining method of epoxy-embedded lymphatic and hemopoietic tissues in autoradiograms. PMID- 4136500 TI - A study of Danish snuff-induced oral leukoplakias. PMID- 4136501 TI - A survey of the chymotryptic peptides of the assembly protein of bacteriophage MS2. PMID- 4136502 TI - A systematic method for the detection of experimentally induced hyperplasia and early neoplasia in the urinary bladder. PMID- 4136503 TI - A working model for oncogenic DNA virus replication. PMID- 4136504 TI - Aberrant restriction and modification of a colicin-tolerant strain of Escherichia coli. PMID- 4136505 TI - Accumulation of coiliodal 198Au in normal bone marrow of rabbits. Microscopic and autoradiographic investigation. PMID- 4136506 TI - Accumulation of digoxin by canine choroid plexus. PMID- 4136508 TI - Acridine orange staining of epithelial cells in strong salt solution. PMID- 4136507 TI - Acid mucosaccharide-containing structures in the gall bladder epithelium of the rabbit as seen with the electron microscope. PMID- 4136509 TI - Acute lymphocytic leukemia. Cytochemistry and ultrastructure. PMID- 4136510 TI - Adrenalectomy with chemotherapy in the treatment of advanced breast cancer: objective and subjective response rates; duration and quality of life. PMID- 4136511 TI - Age related development of humoral immunity in normal children and in children with immunodeficiencies. PMID- 4136512 TI - Age variation in the uptake of radioiodine in thyrotoxicosis. PMID- 4136513 TI - Ageing, immune response, and mortality. PMID- 4136514 TI - Allergen-specific IgE in atopic dermatitis. PMID- 4136515 TI - Alopecia mucinosa with neurofollicular changes. PMID- 4136516 TI - Alpha 1-fetoprotein and carcinoembryonic antigen in a patient with carcinoid of the stomach. PMID- 4136517 TI - Alpha-fetoprotein in bovine hepatocellular carcinoma. PMID- 4136518 TI - Amino acid analysis with fluorescamine of stained protein bands from polyacrylamide gels. PMID- 4136519 TI - Amino acid sequence at the haem region of cytochrome c2 from Rhodopseudomonas palustris, strain X. PMID- 4136520 TI - An antigen in Hodgkin's disease tissue cultures: radioiodine-labeled antibody studies. AB - An antiserum was prepared in rabbits against an antigen obtained by density gradient sedimentation of centrifuged medium from monolayer cultures of spleens involved by Hodgkin's disease. The antiserum was tested by isotopic antibody techniques with cells from each of eight cultures derived from spleens involved by Hodgkin's disease, four cultures derived from normal adult spleen, and one culture each of fetal spleen and thymus. By an indirect radioiodine-labeled antibody assay, anti-Hodgkin's disease globulin reacted with an antigen on the surface of cells from the Hodgkin's disease cultures, the quantity of which was related to the number of target cells and the amount of antibody used. This Hodgkin's disease tissue-culture antigen did not react with a rabbit antiserum against fractionated medium from a normal spleen culture, nor against noncultured Hodgkin's disease tumor tissue. The tumor specificity of the Hodgkin's disease tissue-culture antigen was assessed by a direct technique using (125)I-labeled anti-Hodgkin's disease globulin absorbed with either cultured Hodgkin's disease cells or with cultured normal cells. By this method the quantity of antigen on cells from Hodgkin's disease cultures was 15- to 30-fold greater than that on cells from normal cultures. The Hodgkin's disease tissue-culture antigen is intimately associated with the propagation of the tumor in monolayer cultures, but its identity has not been established: it could be a viral component, a tumor or fetal antigen, or a normal tissue constituent. PMID- 4136521 TI - An arousal pattern in children with organic cerebral dysfunction. PMID- 4136522 TI - An electronic circuit for detection of EEG seizures recorded with implanted electrodes. PMID- 4136523 TI - An immunohistochemical study of the skin of healthy individuals. PMID- 4136524 TI - An inexpensive device for rapid destaining of cylindrical and slab acrylamide gels. PMID- 4136525 TI - An investigation on the chemical nature of the cuticle of a polychaete Nereis diversicolor (Annelida). PMID- 4136526 TI - An unusual case of massive hypertrophy of the breasts. PMID- 4136527 TI - Animal models of the asthmatic state. PMID- 4136528 TI - Anorexia nervosa: a clinical, psychiatric, and laboratory study. I. Clinical and laboratory investigation. PMID- 4136530 TI - Anti-reticulin antibodies in malabsorption syndromes. PMID- 4136529 TI - Antenatal diagnosis and lung maturation in anencephaly. PMID- 4136531 TI - Antibiotic concentrations in relation to structural changes in maxillary sinus mucosa following intramuscular or peroral treatment. PMID- 4136532 TI - Antibodies recognise specific structures of triple-helical polynucleotides built on poly(A) or poly(dA). PMID- 4136533 TI - Antibodies to chick-tendon procollagen. Affinity purification with the isolated disulfide-linded NH2-terminal extensions and reactivity with a component in embryonic serum. PMID- 4136534 TI - Antibodies to DNP, DNP-glycylglycylglycine and DNP-p-aminobenzoylglutamate. PMID- 4136535 TI - Antibody response to different determinants on carcinoembryonic antigen (CEA). PMID- 4136536 TI - Antigen-dependent alterations in the lipid composition of the CNS in guinea pigs with experimental allergic encephalomyelitis. PMID- 4136537 TI - Antigenic determinants in the N-terminal halves of human kappa-chains; their relation to the variable region subgroups. PMID- 4136538 TI - Antigenic differences between the ends and shafts of sex pili. PMID- 4136539 TI - Antigenic differences between T and B lymphocytes in man. PMID- 4136540 TI - Antigenic expression and cross reactions in HL-A variants of lymphoid cell lines. PMID- 4136541 TI - Argininosuccinic aciduria. Report of three cases and the effect of high and reduced protein intake on the clinical state. PMID- 4136542 TI - Aristedes: a second century case report. PMID- 4136543 TI - Arthur Henry Jacobs. PMID- 4136544 TI - Assessment of coma and impaired consciousness. A practical scale. PMID- 4136545 TI - Assignment of a gene for adenosine deaminase to human chromosome 20. PMID- 4136547 TI - Association of house-dust and grass-pollen allergies with specific IgA antibody deficiency. PMID- 4136546 TI - Association between maternal Herpesvirus infections and congenital malformations. PMID- 4136548 TI - Auditory and visual evoked potentials during hyperoxia. PMID- 4136549 TI - Autofluorescence of drusen of the optic nerve head. PMID- 4136550 TI - Automated analysis of deoxyribonucleic acid, protein and nuclear to cytoplasmic relationships in tumor cells and gynecologic specimens. PMID- 4136551 TI - Automated autoradiographic grain counting in human determined context. PMID- 4136552 TI - Automated classification of normal and abnormal leukocytes. PMID- 4136553 TI - Autosomal dominant insensitivity to pain with hyperplastic myelinopathy and autosomal dominant indifference to pain. PMID- 4136554 TI - Axonal transport of adenosine and uridine derivatives and transfer to postsynaptic neurons. PMID- 4136555 TI - B cell, T cell and monocyte origin of the guinea pig L2C leukemia, mouse lymphomas and human leukemias and lymphoblastic cell lines. PMID- 4136556 TI - Behaviour of serum immunoglobulins during and after intravenous administration of gamma-globulins in patients with antibody deficiency syndrome. PMID- 4136557 TI - Behaviour of some enzymes in rat kidney in acute poisoning with furfural. PMID- 4136559 TI - Better techniques for bagging stomas. 3. Ileostomies. PMID- 4136558 TI - Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse. PMID- 4136560 TI - Binding capacity of (NH4)2SO4-precipitate (25 percent-65 percent) of PH 5 enzyme of rat liver, after fasting and refeeding. PMID- 4136561 TI - Binding of dihydrostreptomycin to ribosomes from viomycin-sensitive and resistant strains of Mycobacterium smegmatis. PMID- 4136562 TI - Binding of thyroglobulin and thyroglobulin-antithyroglobulin immune complex to extraocular muscle membrane. PMID- 4136563 TI - Bioassay of growth hormone, I, Determination of longitudinal bone growth with tetracycline in hypophysectomized rats. PMID- 4136564 TI - Biochemical properties of histocompatibility antigens. PMID- 4136565 TI - Biochemical side effects of drugs in the elderly. PMID- 4136566 TI - Biophysical differentiation between lymphocytes from healthy donors, patients with malignant diseases and other disorders. AB - Changes in the structuredness of the cytoplasmic matrix (SCM) of human lymphocytes induced by PHA, CaBP and EF were studied with the technique of fluorescence polarization. The study suggests that the SCM test may offer a new and fast technique for the detection of malignant growth. PMID- 4136568 TI - Blood granulocyte staining with acridine orange. Changes with infection. PMID- 4136567 TI - Biosynthesis of small peptides. PMID- 4136569 TI - Blood pressure and heart rate in the rabbit during animal hypnosis. PMID- 4136570 TI - Bowel transit-times in two populations experiencing similar colon-cancer risks. PMID- 4136571 TI - Bowen's illumitran modified for mass-slide duplication. PMID- 4136572 TI - Breast cancer: molecular basis for a viral etiology. PMID- 4136573 TI - Bronchial brush biopsy in Hodgkin's disease. PMID- 4136575 TI - Calcium translocation by cells. PMID- 4136574 TI - Calcitonin secretion and APUD characteristics of naturally occurring medullary thyroid carcinomas in rats. PMID- 4136576 TI - Capability of lambs to absorb immunoproteins from freeze-dried bovine colostrum. PMID- 4136577 TI - Cardiology patient simulator. Development of an animated manikin to teach cardiovascular disease. PMID- 4136578 TI - Care after nasal surgery. PMID- 4136579 TI - Cell structure and function in the visual cortex of the cat. AB - 1. The organization of the visual cortex was studied with a technique that allows one to determine the physiology and morphology of individual cells. Micro electrodes filled with the fluorescent dye Procion yellow were used to record intracellularly from cells in area 17 of the cat. The visual receptive field of each neurone was classified as simple, complex, or hypercomplex, and the cell was then stained by the iontophoretic injection of dye.2. Fifty neurones were successfully examined in this way, and their structural features were compared to the varieties of cell types seen in Golgi preparations of area 17. The majority of simple units were stellate cells, whereas the majority of complex and hypercomplex units were pyramidal cells. Several neurones belonged to less common morphological types, such as double bouquet cells. Simple cells were concentrated in layer IV, hypercomplex cells in layer II + III, and complex cells in layers II + III, V and VI.3. Electrically inexcitable cells that had high resting potentials but no impulse activity were stained and identified as glial cells. Glial cells responded to visual stimuli with slow graded depolarizations, and many of them showed a preference for a stimulus orientation similar to the optimal orientation for adjacent neurones.4. The results show that there is a clear, but not absolute correlation between the major structural and functional classes of cells in the visual cortex. This approach, linking the physiological properties of a single cell to a given morphological type, will help in furthering our understanding of the cerebral cortex. PMID- 4136580 TI - Cell surface markers for human T and B lymphocytes. PMID- 4136581 TI - Cell to cell transmission of virus in the central nervous system. I. Subacute sclerosing panencephalitis. PMID- 4136582 TI - Cell-wall structure, mitosis and urease activity in Torulopsis species of high GC content. PMID- 4136583 TI - Ceroid-like pigment in age changes of human cartilage. PMID- 4136584 TI - Changes in canine mammary gland histology during the estrous cycle. PMID- 4136585 TI - Changes in immunospecificity and biologic activity of bovine insulin due to subsequent removal of the amino acids B1, B2, and B3. PMID- 4136586 TI - Changes in the activity and isozymic forms of lactic dehydrogenase in the rabbit oviduct following copulation. PMID- 4136587 TI - Changing enzyme patterns in chick organs during development. PMID- 4136588 TI - Characteristics of the conglutinating substance of sheep serum. AB - The conglutinating factor in sheep serum was characterized utilizing its ability to react with sensitized erythrocytes which had been alexinated with horse complement. The conglutinating substance in sheep serum was inactivated by the action of 2-mercaptoethanol, did not require calcium ions for its activity, was not inhibited by N-acetyl-D-glucosamine or L-fucose sugars and did not react directly with zymosan. All these activities distinguish this serum factor from bovine conglutinin. These data show that the conglutinating factor in sheep serum is an immunoconglutinin. Reactivity of sheep immunoconglutinin with both heterologous and autologous complement was demonstrated. PMID- 4136589 TI - Chronic myelomonocytic leukemia in adults. PMID- 4136590 TI - Cinefilm and EEG recording during "hand-waving" attacks of an epileptic, photosensitive child. PMID- 4136591 TI - Circulating immune complexes in human neuroblastoma: direct assay and role in blocking specific cellular immunity. PMID- 4136592 TI - Clindamycin effects on experimental ocular toxoplasmosis in the rabbit. PMID- 4136593 TI - Clinical cardiovascular pharmacology of dobutamine. A selective inotropic catecholamine. PMID- 4136594 TI - Clinical use of narcotic analgesics in terminal cancer. PMID- 4136595 TI - Clinico-roentgenological characteristics of pathogenesis of mandibular-joint ankylosis. PMID- 4136596 TI - Closed prostatectomy for relief of obstruction. PMID- 4136597 TI - Closure of the uterine lumen at implantation in senescent golden hamsters. PMID- 4136598 TI - Collagenolytic activity in rheumatoid nodules. I. Effect on acid-soluble tropocollagen. PMID- 4136599 TI - Color information in blood cells. PMID- 4136601 TI - Comments on estimations and tests of EEG amplitude distributions. PMID- 4136602 TI - Comments on the method of analysis of the proteins from nuclear particles. PMID- 4136600 TI - Colored reverse-banding of human chromosomes with acridine orange following alkaline-formalin treatment: densitometric validation and applications. PMID- 4136603 TI - Comparison of effects of glucagon and valinomycin on rat liver mitochondria and cells. PMID- 4136604 TI - Competitive inhibition of reagin-mediated histamine release by a human IgG2 myeloma protein. PMID- 4136605 TI - Complement-independence of tolerance induction. PMID- 4136606 TI - Computer-assisted tomography (EMI scanner). Its place in investigation of suspected intracranial tumours. PMID- 4136607 TI - Computer-based electronic cell volume analysis with the AMAC II transducer. PMID- 4136608 TI - Computer-controlled multiparameter analysis and sorting of cells and particles. PMID- 4136609 TI - Computer-oriented analysis of human chromosomes. IV. Deoxyribonucleic acid-based centromeric index. PMID- 4136610 TI - Conglomerates of tubular structures in BCG-induced alveolar macrophages revealed by negative staining. PMID- 4136611 TI - Considerations on the use of analgesic drugs in different stages of neoplastic diseases. PMID- 4136612 TI - Contributions to the study of the chemical nature of the nucleolar argentophil substance. PMID- 4136613 TI - Control of photosynthetic oxygen evolution by the internal pH of the chloroplast thylakoid. Inhibition of photosynthetic oxygen evolution by uncouplers at high pH and restoration of electron flow by an artificial electron donor for photosystem II. PMID- 4136614 TI - Coronal topography of human auditory evoked responses. PMID- 4136615 TI - Correction of post traumatic enophthalmos. PMID- 4136616 TI - Cotrimoxazole in the treatment of non-gonococcal urethritis. PMID- 4136617 TI - Critical-point drying: rapid method for the determination of bacterial extracellular polymer and surface structures. AB - The relative amount of extracellular polymer which remains about Azotobacter vinelandii, Zoogloea ramigera, Klebsiella pneumoniae, and Diplococcus pneumoniae after critical-point drying was studied by electron microscopy. The results obtained with this technique are compared to those obtained with methods that illustrate extracellular polymer, such as freeze-etching and ruthenium red staining. Comparative results indicate critical-point drying to be a rapid, reliable method for the determination of capsule-like polymer surrounding bacterial cells. In addition, critical-point drying can be used to observe morphogenetic changes, such as vesicle production. PMID- 4136618 TI - Cyclic AMP induced growth promotion in sunflower callus tissue. PMID- 4136620 TI - Cytochemical localization of nucleic acids with gallocyanin. PMID- 4136619 TI - Cytochemical and morphologic identification of macrophages and eosinophils in tissue cultures of normal human bone marrow. PMID- 4136621 TI - Danger signals in the separation-individuation process. The observations and formulations of Margaret S. Mahler. PMID- 4136622 TI - Dean's lecture. Immunoglobulin E and reaginic hypersensitivity. PMID- 4136623 TI - Decarboxylation of exogenous L-5-hydroxytryptophan after destruction of the cerebral raphe system. PMID- 4136625 TI - Demonstration of lymphocyte nucleoli. PMID- 4136624 TI - Demonstration of carcinoembryonic antigens (CEA), nonspecific cross-reacting antigens (NCA) and an associated alpha protein in normal human tissues and fluids by immunodiffusion techniques. PMID- 4136626 TI - Deoxyribonucleic acid cytochemistry for automated cytology. PMID- 4136627 TI - Detection of cytochrome P-450 in subcellular fractions of Endomycopsislipolytica grown on n-hexadecane. PMID- 4136628 TI - Detection of dengue cell-surface antigens by peroxidase-labeled antibodies and immune cytolysis. AB - The appearance of dengue-specific plasma membrane (DSPM) antigens in infected LLC MK(2) cell cultures was studied by (51)Cr release in immune cytolysis and at an ultrastructural level using peroxidase-labeled antibodies. DSPM antigen was first detected at 36 h with electron microscopy in approximately 30% of the cells, and this percentage did not increase with time. However, both surface staining with peroxidase-labeled antibodies and (51)Cr release indicated that the amount of DSPM antigen per cell increases with time. The appearance of (51)Cr release in immune cytolysis experiments with dengue-infected cells occurred much later than the peak of infectious virus release. This was in sharp contrast to immune cytolysis with a group A arbovirus, Eastern equine encephalitis, in which the kinetics of release of infectious virus and (51)Cr release were identical. This suggests different mechanisms of insertion of viral plasma membrane antigens in Eastern equine encephalitis and dengue-infected LLC-MK(2) cells. PMID- 4136629 TI - Detection of nitrogenase components and other nonheme iron proteins in polyacrylamide gels. PMID- 4136630 TI - Development and application of new equipment for transrectal ultrasonography. PMID- 4136631 TI - Development of chicken erythrocyte alloantigens in ontogenesis. PMID- 4136632 TI - Dexamethasone (DXM) effect on the histamine-releasing activity of endotoxin. PMID- 4136633 TI - Different mode of action of ribonuclease H in purified alpha and alpha beta ribonucleic acid-directed deoxyribonucleic acid polymerase from avian myeloblastosis virus. PMID- 4136634 TI - Differential extraction of proteins from human placental ribosomes. PMID- 4136635 TI - Disorders of phagocytic cell function. PMID- 4136636 TI - Displaced abomasum in dairy cattle: etiological factors. PMID- 4136637 TI - Dissociation of slow potentials and phasic multiple unit activity. PMID- 4136639 TI - Distribution of HL-A antigens on blood cells. PMID- 4136638 TI - Dissociation of the inhibitory activities of iodoacetamide (IAc) on specific histamine release and lactate production in human leucocytes. PMID- 4136640 TI - Distribution of UDPG-glycogen transferase on isolated rat liver glycogen particles. PMID- 4136641 TI - Douglas Austen Stanley. PMID- 4136642 TI - Drug reactions. 23. Drug induced alopecia. PMID- 4136643 TI - Drug-induced enteropathy characterized by lipid in macrophages. PMID- 4136644 TI - Drug-induced foam cell reactions in rats. I. Histopathologic and cytochemical observations after treatment with chlorphentermine, RMI 10.393 and Ro 4-4318. PMID- 4136645 TI - Dynamic nuclear magnetic resonance spectroscopy. PMID- 4136646 TI - Dynamics of human sleep sigma spindles. PMID- 4136647 TI - DNA cytophotometry of chromosomes in a case of chronic myelogenous leukemia. PMID- 4136648 TI - Early insulin response to glucose injected intravenously in patients with localized granuloma annulare. PMID- 4136649 TI - Early intervention. Experiences in a Service-Centered Research Program. PMID- 4136650 TI - Ectopic gonadotropin in a case of anaplastic large-cell carcinoma of the lung. AB - A case of ectopic gonadotropin production by a bronchogenic carcinoma is presented. Eleven similar cases have been previously reported. Urine gonadotropin titres appeared related to the size of the tumour mass since they decreased with response to treatment and increased when the tumour started progressing again. The hormone is most probably elaborated and secreted by the tumour cells. PMID- 4136651 TI - Editorial; Hospital medical staffing. PMID- 4136652 TI - Editorial: A prescription for perspiration. PMID- 4136653 TI - Editorial: Alimentary endoscopy for all. PMID- 4136654 TI - Editorial: Antenatal diagnosis of genetic disease. PMID- 4136655 TI - Editorial: Bongo-drum disease. PMID- 4136656 TI - Editorial: Bracken. PMID- 4136657 TI - Editorial: Carcinomatous polymyositis and neuromyopathy. PMID- 4136658 TI - Editorial: Diagnosis and automation. PMID- 4136659 TI - Editorial: Diagnosis of insulinoma. PMID- 4136660 TI - Editorial: Encephalopathy and fatty degeneration of viscera. PMID- 4136661 TI - Editorial: Fire-fighting: an insidious hazard. PMID- 4136662 TI - Editorial: Functional implications of axoplasmic transport. PMID- 4136663 TI - Editorial: Growth-hormone release-inhibiting hormone. PMID- 4136664 TI - Editorial: Haemophilia carriers. PMID- 4136665 TI - Editorial: Immune response genes. PMID- 4136666 TI - Editorial: Is HL-A matching worth while in kidney transplantation? PMID- 4136667 TI - Editorial: Leads in oesophageal cancer. PMID- 4136668 TI - Editorial: Lung tumours in mice exposed to tobacco smoke. PMID- 4136669 TI - Editorial: One-parent families. PMID- 4136670 TI - Editorial: Oral contraceptives and health. PMID- 4136671 TI - Editorial: Penicillins and nephropathy. PMID- 4136672 TI - Editorial: Portacaval anastomosis for metabolic disease. PMID- 4136673 TI - Editorial: Prosopagnosia. PMID- 4136674 TI - Editorial: Quality of laboratory animals. PMID- 4136675 TI - Editorial: Science in China. PMID- 4136677 TI - Editorial: Storm in a private bed. PMID- 4136676 TI - Editorial: Skin infection and the kidney. PMID- 4136678 TI - Editorial: Subcutaneous heparin. PMID- 4136679 TI - Editorial: Sulphasalazine-induced lung disease. PMID- 4136680 TI - Editorial: The coeliac philosophy. PMID- 4136681 TI - Editorial: The latest of L.A.T.S. PMID- 4136682 TI - Editorial: Tobacco substitutes and the Hunter committee. PMID- 4136683 TI - Editorial: Tomorrow's artificial kidney. PMID- 4136684 TI - Editorial: Transtracheal aspiration. PMID- 4136685 TI - Editorial: Ubiquitous HeLa. PMID- 4136686 TI - Editorial: Unto everyone that hath. PMID- 4136687 TI - Editorial: Use and abuse of the Supraregional Assay Service. PMID- 4136688 TI - Effect of beta 2 microglobulin antibody on effector function of T-cell mediated cytotoxicity. PMID- 4136689 TI - Effect of carrier preimmunization on the anti-hapten response in the chicken. PMID- 4136690 TI - Effect of chronic graded doses of ascorbic acid on thyroid activity, protein bound iodine of blood and deiodinase enzyme of peripheral tissues of guinea pigs. PMID- 4136691 TI - Effect of early thymectomy on the cellular changes occuring in the spleen of the clawed toad following administration of soluble antigen. PMID- 4136692 TI - Effect of emetine treatment on kidney aminopeptidase activity. PMID- 4136693 TI - Effect of estrogen on gene expression in the chick oviduct. 3. Hybridization studies with (3H) messenger RNA and (3H) complementary DNA under conditions of DNA excess. PMID- 4136694 TI - Effect of exercise on levels of plasma growth hormone, free fatty acids, and glucose in the pigeon. PMID- 4136695 TI - Effect of sex hormones on feed intake in rats. PMID- 4136696 TI - Effect of short and long term chlorpropamide treatment of insulin release and blood-glucose. PMID- 4136697 TI - Effect of short-term administration of N-nitroso compounds on liver histology and on pentobarbital-induced sleeping time in mice. PMID- 4136698 TI - Effects of bleomycin on 3H-thymidine incorporation in the skin and on the DNA, RNA and ATP syntheses in the primary tumour of patients with vulval carcinoma. PMID- 4136699 TI - Effects of cyclophosphamide on B- and T-lymphocytes in rheumatoid arthritis. PMID- 4136700 TI - Effects of guanethidine and imidazole on histamine response. PMID- 4136701 TI - Effects of ketamine on EEG activity in cats and monkeys. PMID- 4136702 TI - Effects of metabolic inhibitors on vital staining with methylene blue. PMID- 4136703 TI - Effects of post-coital administration of chlormadinone acetate to rats. PMID- 4136704 TI - Electro-acoustic unit for classroom use. PMID- 4136705 TI - Electroencephalographic recordings from deep cerebellar structures in patients with uncontrolled epileptic seizures. PMID- 4136706 TI - Electron microscope study of mitochondrial 60S and cytoplasmic 80S ribosomes from Locusta migratoria. AB - Purified mitochondrial ribosomes (60S) have been isolated from locust flight muscle. Purification could be achieved after lysis of mitochondria in 0.055 M MgCl(2). Mitochondrial 60S and cytoplasmic 80S ribosomes were investigated by electron microscopy in tissue sections, in sections of pellets of isolated ribosomes, and by negative staining of ribosomal suspensions. In negatively stained preparations, mitochondrial ribosomes show dimensions of approximately 270 x 210 x 215 A; cytoplasmic ribosomes measure approximately 295 x 245 x 255 A. From these values a volume ratio of mitochondrial to cytoplasmic ribosomes of 1: 1.5 was estimated. Despite their different sedimentation constants, mitochondrial ribosomes after negative staining show a morphology similar to that of cytoplasmic ribosomes. Both types of particles show bipartite profiles which are interpreted as "frontal views" and "lateral views." In contrast to measurements on negatively stained particles, the diameter of mitochondrial ribosomes in tissue sections is approximately 130 A, while the diameter of cytoplasmic ribosomes is approximately 180-200 A. These data suggest a volume ratio of mitochondrial to cytoplasmic ribosomes of 1:3. Subunits of mitochondrial ribosomes (40S and 25S) were obtained by incubation under dissociating conditions before fixation in glutaraldehyde. After negative staining, mitochondrial large (40S) subunits show rounded profiles with a shallow groove on a flattened side of the profile. Mitochondrial small subunits (25S) display elongated, triangular profiles. PMID- 4136707 TI - Electron microscopic studies of chain initiation complexes and polysomes. PMID- 4136708 TI - Electron microscopy of enzymes. PMID- 4136709 TI - Electrophoretic types of transaldolase, transketolase, and other enzymes in bifidobacteria. PMID- 4136710 TI - Electrophysiological investigations of methylmercury intoxication in humans. Evaluation of peripheral nerve by conduction velocity and electromyography. PMID- 4136711 TI - Electrophysiological studies of hippocampal, septal and midbrain projections to the hypothalamus of the rat. PMID- 4136712 TI - Elimination of the residual cytoplasmic material by prolonged ribonuclease treatment in gallocyanine-chromalum stained nerve cells fixed in formalin. PMID- 4136713 TI - Elution of antibody from the skin lesions of patients with pemphigus vulgaris. PMID- 4136714 TI - Embryonal sarcoma of the lower urinary tract in children: 5-year survival in 2 cases after radical treatment. PMID- 4136715 TI - Endemic goitre: a public health problem in Maharashtra, India. PMID- 4136716 TI - Endogenous RNA-directed DNA polymerase activity in virions of RNA tumor viruses and in a fraction from normal chicken cells. PMID- 4136717 TI - Endometriosis: histological and histochemical findings. PMID- 4136718 TI - Endoscopy in gastrointestinal bleeding. PMID- 4136719 TI - Enhancement of the immune response of genetically thymus-less mice by different cell populations. PMID- 4136720 TI - Enzyme-histochemical studies on the cycle in the endocervix and on the isthmus. PMID- 4136721 TI - Epithelial collagens and glycosaminoglycans in the embryonic cornea. Macromolecular order and morphogenesis in the basement membrane. AB - The embryonic corneal epithelium synthesizes both collagen and chondroitin sulfate and excretes them across the basement membrane into the subepithelial space where they assemble into a spiraling orthogonal matrix of fibrils. The assembly of collagen into fibrils is first apparent at the outer face of the basement membrane in a region of ordered chondroitin sulfate molecules. Hyaluronate, another morphogenetically important corneal macromolecule, is produced at these early stages only by the inner endothelium. These correlated biosynthetic and ultrastructural data demonstrate discrete macromolecular products of the two corneal epithelia with differing morphogenetic properties and functions. PMID- 4136722 TI - Epstein-Barr virus-associated complement-fixing and nuclear antigens in Burkitt lymphoma biopsies. PMID- 4136724 TI - Estimation of the activation energy for millisecond delayed fluorescence from uncoupled chloroplasts. PMID- 4136723 TI - Establishment and characteristics of two unique cell lines from patients with lymphosarcoma. PMID- 4136725 TI - Ethanol induced alterations of axoplasmic flow in retinal ganglion cells. PMID- 4136726 TI - Evaluation of the nutritional value of proteins of rape, turnip rape and yellow mustard seed by larvae of the yellow mealworm, Tenebrio molitor L. PMID- 4136727 TI - Evaluation of the T. pallidum haemagglutination (TPHA) test for syphilis on "problem sera". PMID- 4136728 TI - Evidence for a noradrenergic and dopaminergic mechanism in the hyperactivity produced by 4, alpha-dimethyl-m-tyramine (H 77-77) in rats. PMID- 4136729 TI - Evidence for a physiologic role of erythropoietin in fetal erythropoiesis. PMID- 4136730 TI - Evidence for a polysaccharide surface coat in the developmental stages of Leishmania donovani: a fine structure-cytochemical study. PMID- 4136731 TI - Evolutionary relationships between rat and mouse chromosomes. PMID- 4136732 TI - Experimental chemotherapy in leprosy, then and now. PMID- 4136733 TI - Experimental corneal wound strength. PMID- 4136734 TI - EEG radio telemetry. PMID- 4136735 TI - Failure of cytosine arabinoside in treating smallpox. A double-blind study. PMID- 4136736 TI - Familial neuromuscular disease with "myotubes". PMID- 4136737 TI - Five years' experience with iodine-125 therapy of Graves' disease. PMID- 4136738 TI - Five years' experience with the Bjork-Shiley tilting-disc valve in isolated aortic valvular disease. PMID- 4136740 TI - Fluorescence labeling of mouse alloantibodies. PMID- 4136739 TI - Flow microfluorometric analysis of cell killing with cytotoxic drugs. PMID- 4136741 TI - Fluorescence spectroscopic and fading behavior of Ehrlich's hyperdiploid mouse ascites tumor cells supravitally stained with acridine orange. PMID- 4136742 TI - Fluorometric properties of the bibenzimidazole derivative Hoechst 33258, a fluorescent probe specific for AT concentration in chromosomal DNA. PMID- 4136743 TI - Follow-up study of serum immunoglobulins in thymectomized cases of myasthenia gravis. PMID- 4136744 TI - Functional and morphologic characteristics of complement receptor lymphocytes in mice. PMID- 4136745 TI - Functional and structural proteins of the nervous system. Concluding remarks. PMID- 4136746 TI - Further studies of thyroid function tests in the elderly at home. PMID- 4136747 TI - Genetic alterations in tumor cells resulting in their escape from the immune response. PMID- 4136748 TI - Genetic control and immunity. PMID- 4136749 TI - Genitourinary-tract problems of the aged male. PMID- 4136750 TI - Geoffrey Platt. PMID- 4136751 TI - Germinal centers: a microenvironment for the production of antibody forming cell precursors? PMID- 4136752 TI - Globin messenger RNA synthesis and processing during haemoglobin induction in Friend cells. I. Evidence for transcriptional control in clone M2. PMID- 4136753 TI - Glomerular lesions in dysproteinemias. PMID- 4136754 TI - Glomerulonephritis associated with hepatitis-B surface antigen immune complexes in children. PMID- 4136755 TI - Glucocorticoid-receptor complexes in rat thymus cells. "Cytoplasmic"-nuclear transformations. PMID- 4136756 TI - Glycosaminoglycans of epidermis and dermal collagen in dog skin. PMID- 4136757 TI - Glycosuria and hyperglycaemia after kidney transplantation. PMID- 4136758 TI - Goldenhar's syndrome, typical and atypical forms. Report of two cases. PMID- 4136759 TI - Gonococcal disease. PMID- 4136760 TI - Haemagglutination and cytotoxic studies of H-2. V. T-e anti-27, 28, 29 family of antibodies. PMID- 4136761 TI - Hairy hatman to the rescue. PMID- 4136762 TI - Hematologic automation by use of continuous flow systems. PMID- 4136763 TI - Hemorrhagic shock in the rat: metabolic changes in brain and liver. PMID- 4136764 TI - Heparin-precipitable fraction (HPF) in an unselected material of dermatological inpatients. PMID- 4136765 TI - Hepatic morphologic alterations in dogs given 1-t-butylamino-3-(2-chloro-5 methylphenoxy)-2-propanol hydrochloride. PMID- 4136766 TI - Hepatitis B antigen (HBAg) in the Republic of Ireland: distribution of ad and ay subtypes. PMID- 4136768 TI - High energy phosphate compounds of gastric tissue in rats. PMID- 4136767 TI - Hepatitis B antigen: antigenic sites related to human serum proteins revealed by affinity chromatography. AB - Hepatitis B antigen-associated particles, isolated from sera of antigen carriers, were submitted to affinity chromatography on columns of insolubilized antibodies to normal human plasma. The particles adsorbed to the immunosorbent at pH 7.2 and were subsequently eluted at pH 2.2. Exposure of the particles to 8 M urea, 5 M KI, pH 2.2, detergents, organic solvents, or proteolytic enzymes failed to prevent their subsequent adsorption to the immunosorbent. This suggests that antigenic determinants related to human plasma proteins are constituent components of hepatitis B antigen-associated particles. These determinants are distinct from the group-specific (a) and subtype-specific (d or y) sites of the hepatitis B antigen and appear to be related to antigenic specificities on prealbumin, albumin, apolipoproteins C and D, and the gamma-chain of immunoglobulin G. PMID- 4136769 TI - High frequency of antibiotic-resistant enterobacteria in the River Stour, Kent. PMID- 4136770 TI - High resolution shading correction. PMID- 4136771 TI - High titre antiserum specific to aldosterone. PMID- 4136772 TI - High-resolution analysis of the modified quarter-stagger model of the collagen fibril. PMID- 4136773 TI - Histamine release from mast cells by highly purified phospholipase C (alpha toxin) and theta-toxin from Clostridium perfringens. PMID- 4136774 TI - Histamine release in endotoxin shock: effect of dexamethasone administration. PMID- 4136776 TI - Histochemical evidence for the existence of adreno-melanogenic tissue in the teleost fish Nandus. PMID- 4136775 TI - Histochemical and radioautographic studies of normal human fetal colon. PMID- 4136777 TI - Histochemical investigations on the epidermis of the electric fish Malopterurus electricus Lacep. (Teleostei: Malopteruridae). PMID- 4136778 TI - Histochemical studies of the monoamine oxidase during the development of the chick. PMID- 4136780 TI - Histochemistry of acid glycosaminoglycans (mucopolysaccharides) in the branchial epithelium of Selachians. PMID- 4136779 TI - Histochemistry and ultrastructure of the cell surfaces of the guinea pig kidney with quantitative data on carbohydrate components of glycosaminoglycans of kidney. PMID- 4136782 TI - Histological evidence supporting the inferior olive as the major source of cerebellar climbing fibers in the rat. PMID- 4136781 TI - Histochemistry of provisional calcification of cartilage in heterotopic implants of bone matrix. PMID- 4136783 TI - Home treatment for patients with haemophilia. PMID- 4136784 TI - Homing of B-lymphocytes to follicles: specific retention of immunologically committed cells. PMID- 4136785 TI - Homozygous hypercholesteraemia and the portacaval shunt. The need for a concerted attack by surgeons and clinical researchers. PMID- 4136786 TI - Hyaline ("colloid") cytoplasmic inclusions in motoneurones in association with familial micrencephaly, retardation and seizures. PMID- 4136787 TI - Hybridization characteristics of enzymatically synthesised DNA complementary to mouse immunoglobulin messenger RNA. PMID- 4136788 TI - Hyperthyroidism and pregnancy. PMID- 4136789 TI - Hypothalamo-hypophysial neurosecretory and portal system of the Indian wall lizard, Hemidactylus flaviviridis. PMID- 4136790 TI - HL-A antigens in leprosy. PMID- 4136791 TI - HL-As and the immune response to gluten. PMID- 4136792 TI - Identification of cell surface immunoglobulin markers by protein A-containing fluorescent staphylococci. PMID- 4136793 TI - Identification of chromosome anomalies in the blastic phase of chronic myelocytic leukemia (CML) by Giemsa- and quinacrine-banding techniques. PMID- 4136794 TI - Identification of viral reverse-transcriptase. PMID- 4136795 TI - IgG complexes in serum of rheumatoid arthritis patients. PMID- 4136796 TI - Immune activation of B cells: evidence for "one non-specific triggering signal" not delivered by the Ig receptors. PMID- 4136797 TI - Immunochemical studies on human fibrinogen and its fragments. Cross-reactivity of NH2-terminal "Disulfide Knot" and related structures as determined by radioimmunoassay. PMID- 4136798 TI - Immunodeficiency diseases: functional classification. PMID- 4136799 TI - Immunofluorescent localization of alpha-fetoprotein synthesis in endodermal sinus tumor (yolk sac tumor). PMID- 4136800 TI - Immunoglobulin surface determinants on chicken lymphoid cells. PMID- 4136801 TI - Immunological responses of guinea pigs to a synthetic autoantigen of brain. PMID- 4136802 TI - Immunoreactive polypeptide hormones in the pancreas and gut of the lamprey. PMID- 4136803 TI - Immunosuppression of the thymectomized fetal lamb and its neonatal reconstitution. PMID- 4136804 TI - Importance of coagulase-negative staphylococci as pathogens in the urinary tract. PMID- 4136805 TI - Importance of feed as an unavoidable source of pesticide contamination in poultry meat and eggs. 1. residues in feedstuff. PMID- 4136806 TI - Importance of feed as an unavoidable source of pesticide contamination in poultry meat and eggs. 2. Residues in eggs and tissues. PMID- 4136807 TI - In vitro antibody response to a distinct antigenic determinant of Escherichia coli beta-D-galactosidase. Effect of antigen dosage and co-cultivation of lymph node fragments on peak titres and duration of antibody synthesis. PMID- 4136808 TI - In vitro organ culture of adult human and mouse skin. PMID- 4136809 TI - In vitro studies of testosterone and 5alpha-dihydrotestosterone binding in benign prostatic hypertrophy. PMID- 4136810 TI - Incorporation of L-dopa, L-alpha-methyldopa and DL-isoproterenol into guinea pig hair. PMID- 4136811 TI - Increased serum immunoglobulin levels following portacaval shunt in the normal rat. AB - Normal rats subjected to end-to-side portacaval shunt showed decreased survival and weight gain, a progressive fall in serum albumin and reciprocal rise in serum gamma globulin when compared with sham-operated controls for 12 weeks. Antibacterial lipopolysaccharide antibody was detected in significant titre at the sixth and twelfth weeks. It is suggested that the elevated levels of gamma globulin and reversal of albumin/globulin ratios noted in these animals may represent an immune response to bacterial lipopolysaccharides released into the systemic circulation as a result of the portacaval shunt. The hyperglobulinaemia of cirrhosis in human subjects may have a similar aetiology. PMID- 4136812 TI - Increased DNA synthesis in vitro in guinea-pigs unresponsive to DNP--skin protein conjugate. PMID- 4136813 TI - Indications for early haemodialysis in multiple trauma. PMID- 4136814 TI - Indirect fluorescent antibody techniques for demonstration of trout viruses and corresponding antibody. PMID- 4136815 TI - Induction and suppression of experimental allergic encephalomyelitis in the non human primate. PMID- 4136816 TI - Induction of anti-alloantibodies by alloantibody fragments. PMID- 4136817 TI - Induction of anti-hapten antibody responses against haptens conjugated to autologous and heterologous proteins. PMID- 4136818 TI - Induction of host nuclear DNA synthesis in coccidia-infected chicken intestinal cells. PMID- 4136819 TI - Influence of fasting and refeeding on the elongation process in rat liver. PMID- 4136820 TI - Influence of hypoxia on the occurrence of the lactate dehydrogenase release from isolated perfused rat heart. PMID- 4136821 TI - Influence of light, riboflavin, and carotene on the response of rats to the acute toxicity of aflatoxin and monocrotaline. PMID- 4136822 TI - Influence of muscular exercise on plasma level of growth hormone in diabetics with and without retinopathy. PMID- 4136823 TI - Influence of possible HL-A haploidentity on renal-graft survival in Eurotransplant. PMID- 4136824 TI - Inhibition of guinea-pig complement by derivatives of benzamidine. I. Effect of p nitrophenylureido derivative of m-(m-phenoxypropoxy)benzamidine on guinea-pig complement component haemolytic activity. PMID- 4136825 TI - Inhibition of RNA directed DNA polymerase of murine leukemia virus by 2'-O alkylated polyadenylic acids. PMID- 4136826 TI - Innervation of human atrioventricular valves. PMID- 4136827 TI - Interaction aspects of antimycobacterial drugs in the chemotherapy of tuberculosis. I. Role of individual antituberculous drugs in drug regimens used in the chemotherapy of human tuberculosis. PMID- 4136828 TI - Interaction between erythrocyte membrane proteins and complement components. I. The role os -S-S linkages as revealed by two-dimensional sodium dodecylsulfate polyacrylamide gel electrophoresis. PMID- 4136829 TI - Interaction of bishydroxycoumarin with chloral hydrate and trichloroethyl phosphate. PMID- 4136830 TI - Interaction of human anaphylatoxin C3a with rat mast cells demonstrated by immunofluorescence. PMID- 4136831 TI - Interactions of fluorescent mercurial compounds and acidic fluorochromes with isolated living cells and nuclei. PMID- 4136832 TI - Interference with formation and expression of RNA tumor virus information: rationale and experimental results. PMID- 4136833 TI - Interneuronal epileptic discharges related to spike-and-wave cortical seizures in behaving monkeys. PMID- 4136835 TI - Intrinsic mutagenesis, an interpretation of the pathogenesis of xeroderma pigmentosum. PMID- 4136834 TI - Intracellular aluminum binding; a histochemical study. PMID- 4136836 TI - Iodine contamination of the serum protein-bound iodine: incidence and clinical significance. AB - Iodine contamination as defined by the combination of a raised (PBI-T(4)I) difference and low (131)I neck uptake was found in 38 (17.5%) of 217 euthyroid patients. Of these, 17 had PBI levels of greater than 20 mug/dl but in the remainder levels were clinically feasible. In only 21 was there a history of exposure to iodine. Two of 12 hypothyroid patients had PBI levels well within normal limits. False elevation of the PBI is thus shown to be common. It is neither always obvious nor can it be easily avoided. The PBI is not an acceptable alternative to T(4) estimation by other methods. PMID- 4136837 TI - Irradiated cerebellar medulloblastoma in a monozygotic twin. Growth, neurology and chromosomes 13 years after treatment. PMID- 4136839 TI - Isolation and characterization of a 5S RNA-protein complex from human placental ribosomes. PMID- 4136838 TI - Isoelectric focusing of proteins exposed to sodium dodecyl sulfate. PMID- 4136841 TI - Isolation of a new urine metabolite excreted in generalized congenital analgesia. PMID- 4136840 TI - Isolation and partial characterization of macromolecular urinary aggregates containing carcinoembryonic antigen-like activity. AB - Carcinoembryonic antigen-like substances in the urine of patients with bladder carcinoma and of healthy male subjects occur in a wide range of average molecular sizes. Some of these substances are glycoproteins giving reactions of antigenic identity with carcinoembryonic antigen (CEA) derived from colorectal carcinoma and occur in aggregation with proteins showing antigen specificities of albumin, haptoglobin and the heavy chains of immunoglobulins G, A and M. Recoveries of CEA like activities, following Sepharose 4B chromatography of urinary materials of molecular size > 3 * 10(4), varied from 40 to 1530%. Treatment with 1 mol/1 HClO(4) caused an apparent solubilization of 85% of the CEA-like activity of such materials from the urine of a patient with bladder carcinoma and raised the specific CEA-like activity of the solubilized product to 379% of that of the untreated materials. PMID- 4136842 TI - Isolation of a surface glycoprotein of human platelets. PMID- 4136843 TI - Isolation, structure and synthesis of a new heterocyclic glucoside from Lathyrus odoratus: 2-(beta, D-glucopyranosyl)-3-isoxazolin-5-one. PMID- 4136844 TI - Janet Simpson Ferguson Niven. PMID- 4136845 TI - Labeled staphylococcal protein A as an immunological probe in the analysis of cell surface markers. PMID- 4136846 TI - Laboratory examination of the thyroid. I. In vitro tests. Last of a series. PMID- 4136847 TI - Laboratory examination of the thyroid. 1. In vitro tests. PMID- 4136848 TI - Lack of incorporation of 1:N6-ethenoadenosine triphosphate into yeast tRNAPhe and tRNASer under standard conditions. PMID- 4136850 TI - Late effects of spinal cord irradiation with 300 kV X rays and 15 MeV neutrons. PMID- 4136849 TI - Laryngeal lesions in Urbach-Wiethe disease (lipoglycoproteinosis; lipoid proteinosis; hyalinosis cutis et mucosae). A histopathological and clinical study, including direct laryngoscopical examinations. PMID- 4136851 TI - Letter: "Menstrual toxin" and human fertility. PMID- 4136852 TI - Letter: A cold autoagglutinin in the newborn. PMID- 4136853 TI - Letter: A metabolite of bleomycin A5 in rabbit urine. PMID- 4136854 TI - Letter: Acrodermatitis enteropathica: a lethal inherited human zinc-deficiency disorder. PMID- 4136855 TI - Letter: Adrenal unresponsiveness associated with clobetasol propionate. PMID- 4136857 TI - Letter: Allopurinol and bone-marrow depression. PMID- 4136856 TI - Letter: Afferent blockage, oestrogenic therapy, and malignancy. PMID- 4136858 TI - Letter: Alpha 1-antitrypsin null gene (pi-). PMID- 4136859 TI - Letter: Alpha-fetoprotein radioimmunoassay in blood diseases. PMID- 4136860 TI - Letter: Ampicillin-resistant Haemophilus influenzae meningitis. PMID- 4136861 TI - Letter: Ampicillin-resistant Haemophilus influenzae. PMID- 4136862 TI - Letter: An adverse reaction to althesin. PMID- 4136863 TI - Letter: Angio-immunoblastic lymphadenopathy with dysproteinaemia. PMID- 4136864 TI - Letter: Another case of Whipple's disease? PMID- 4136865 TI - Letter: Apparent emergence of gentamicin-resistant Providencia stuartii during therapy with gentamicin. PMID- 4136866 TI - Letter: Assessment of response to treatment in advanced breast cancer. PMID- 4136867 TI - Letter: Autologous transfusion. PMID- 4136868 TI - Letter: Awareness during anaesthesia. PMID- 4136869 TI - Letter: Bacteriuria in preschool children. PMID- 4136870 TI - Letter: Beta-blocking agents in the treatment of catecholamine-induced symptoms in musicians. PMID- 4136871 TI - Letter: Bilharzial urethral discharge. PMID- 4136872 TI - Letter: Blood-lead levels, behavior, and intelligence. PMID- 4136873 TI - Letter: Bone necrosis in tunnel workers. PMID- 4136874 TI - Letter: Cancer of the cervix: a sexually transmitted infection? PMID- 4136875 TI - Letter: Cerebral intravascular coagulation in diabetic ketoacidosis. PMID- 4136876 TI - Letter: Chemistry of bleomycin. XIV. Biogenetic-like synthesis of (2S, 3S, 4R)-4 amino-3-hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin. PMID- 4136877 TI - Letter: Chemistry of bleomycin. 8. The x-ray structure determination of 4-amino-3 hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin. PMID- 4136878 TI - Letter: Chloromycetin: medical imperialism. PMID- 4136879 TI - Letter: Cholera. PMID- 4136880 TI - Letter: Chondroitinsulphaturia with alpha-L-iduronidase deficiency. PMID- 4136881 TI - Letter: Church, state, and people. PMID- 4136882 TI - Letter: Classification of non-Hodgkin's lymphomas. PMID- 4136883 TI - Letter: Clotting factors in von Willebrand's disease. PMID- 4136884 TI - Letter: Colonoscopic polypectomy. PMID- 4136885 TI - Letter: Comparison of the effects of early and late fixation on Alcian Blue staining in dog skin using two different fixatives. PMID- 4136886 TI - Letter: Complement components in cystic fibrosis. PMID- 4136887 TI - Letter: Congenital heart defects and prenatal sex hormones. PMID- 4136888 TI - Letter: Cryptorchidism. PMID- 4136889 TI - Letter: D.N.C.B. skin test in hepatitis. PMID- 4136891 TI - Letter: Detection of microbial antigens. PMID- 4136890 TI - Letter: Decrease of T lymphocytes during ageing. PMID- 4136892 TI - Letter: Diet and coronary heart-disease. PMID- 4136893 TI - Letter: District community physicians. PMID- 4136894 TI - Letter: Domiciliary physiotherapy. PMID- 4136895 TI - Letter: Emigration and mental subnormality in Northern Ireland. PMID- 4136896 TI - Letter: Endotoxin and stress. PMID- 4136897 TI - Letter: Evaluation of kwashiorkor and marasmus. PMID- 4136898 TI - Letter: Evolution of kwashiorkor and marasmus. PMID- 4136899 TI - Letter: Follow-up of urinary-tract infection in children. PMID- 4136900 TI - Letter: Food antibodies and myocardial infarction. PMID- 4136901 TI - Letter: Food antibodies and myocardial infarction. PMID- 4136902 TI - Letter: Food antibodies and myocardial infarction. PMID- 4136903 TI - Letter: Future of the N.H.S. PMID- 4136904 TI - Letter: Gamma-globulin and congenital rubella. PMID- 4136905 TI - Letter: General practitioners' opinions of a new hospital-discharge letter. PMID- 4136906 TI - Letter: Genetic diagram of the human family. PMID- 4136907 TI - Letter: Geriatrics is medicine. PMID- 4136908 TI - Letter: Geriatrics. PMID- 4136909 TI - Letter: Geriatrics. PMID- 4136910 TI - Letter: Geriatrics. PMID- 4136911 TI - Letter: Glucagon antibodies in diabetic patients. PMID- 4136912 TI - Letter: Group-Z meningococci. PMID- 4136913 TI - Letter: Growth of respiratory syncytial virus in RK13 cells. PMID- 4136914 TI - Letter: Haemagglutination-inhibition slide test for hepatitis-B antigen. PMID- 4136915 TI - Letter: Haemophilia carriers. PMID- 4136916 TI - Letter: Haemorrhagic thyroid cysts in nodular goitre. PMID- 4136917 TI - Letter: Histocompatibility testing in doubtful cases of ankylosing spondylitis. PMID- 4136918 TI - Letter: Hodgkin's disease mortality among physicians. PMID- 4136919 TI - Letter: Hyperosmolar coma in Cushing's disease. PMID- 4136920 TI - Letter: Hypertension: a direction for research. PMID- 4136921 TI - Letter: Hypotension after percutaneous liver biopsy. PMID- 4136922 TI - Letter: Hypotension during administration of angiotensin converting enzyme inhibitor SQ 20,881. PMID- 4136923 TI - Letter: HL-A antigens and coeliac disease. PMID- 4136925 TI - Letter: Imported infections. PMID- 4136924 TI - Letter: Immunoelectron microscopy and histochemistry of HB Ag. PMID- 4136926 TI - Letter: Indomethacin and bone pain. PMID- 4136927 TI - Letter: Industrial action in the N.H.S. PMID- 4136928 TI - Letter: Inhibition of lymphocyte response to stimulants induced by unsaturated fatty acids and prostaglandins. PMID- 4136929 TI - Letter: Ionic shuttles in shock. PMID- 4136930 TI - Letter: Iron and resistance to infection. PMID- 4136931 TI - Letter: Ischaemia times in renal transplants. PMID- 4136932 TI - Letter: Kveim reagent. PMID- 4136933 TI - Letter: Kwashiorkor and tuberculosis. PMID- 4136934 TI - Letter: Lactic acidosis and hyperlactataemia. PMID- 4136935 TI - Letter: Larger doses of immunosuppressive drugs. PMID- 4136936 TI - Letter: Leukaemia and lower-motor-neuron disease. PMID- 4136937 TI - Letter: Levodopa in treatment of myoclonus. PMID- 4136938 TI - Letter: Local chemotherapy for pseudomonas lung abscess. PMID- 4136939 TI - Letter: Local immunity and ulcerative colitis. PMID- 4136940 TI - Letter: Local immunity and ulcerative colitis. PMID- 4136941 TI - Letter: Magnesium deficiency and hypocalcaemia. PMID- 4136942 TI - Letter: Management of acute myocardial infarction. PMID- 4136943 TI - Letter: Manual cardiotocography in labour. PMID- 4136944 TI - Letter: Medical nemesis. PMID- 4136945 TI - Letter: Metabolic and hormonal response to acute myocardial infarction. PMID- 4136946 TI - Letter: Mobile coronary care. PMID- 4136947 TI - Letter: Mobile coronary care. PMID- 4136948 TI - Letter: Mortality and anaemia. PMID- 4136949 TI - Letter: Mycoplasma and fertility. PMID- 4136950 TI - Letter: N.B.T. test in overwhelming bacterial infection. PMID- 4136951 TI - Letter: Nature of crystalline chenodeoxycholic acid. PMID- 4136952 TI - Letter: Nature of nuclear projections in an adenocarcinoma of the breast. PMID- 4136953 TI - Letter: Neonatal cold injury and maternal reserpine administration. PMID- 4136954 TI - Letter: Neural-tube defects and twinning. PMID- 4136955 TI - Letter: New concepts in medical education. PMID- 4136956 TI - Letter: New enterovirus type associated with epidemic of aseptic meningitis and or hand, foot, and mouth disease. PMID- 4136957 TI - Letter: Nitrous-oxide asphyxia. PMID- 4136958 TI - Letter: Nomenclature and abbreviations for vitamin D metabolites. PMID- 4136959 TI - Letter: Non-congenital rubella encephalitis. PMID- 4136960 TI - Letter: Occupational hazard of halothane. PMID- 4136961 TI - Letter: On medical imperialism. PMID- 4136962 TI - Letter: Oral contraception: potential hazards of hormone therapy during pregnancy. PMID- 4136963 TI - Letter: Oral contraceptives and allergy. PMID- 4136964 TI - Letter: Oral contraceptives and health. PMID- 4136966 TI - Letter: Pathologists at the crystal ball. PMID- 4136965 TI - Letter: Pathogens in the urinary tract. PMID- 4136967 TI - Letter: Pathologists at the crystal ball. PMID- 4136968 TI - Letter: Peak-flow meter v. peak-flow gauge. PMID- 4136969 TI - Letter: Penicillinase production by Haemophilus influenzae. PMID- 4136970 TI - Letter: Pentazocine, mefenamic acid and hypertonic-saline abortion. PMID- 4136971 TI - Letter: Peripheral lymphocyte counts in colonic disease. PMID- 4136972 TI - Letter: Phenelzine and acetylator status. PMID- 4136973 TI - Letter: Plasma viscosity and pre-eclampsia. PMID- 4136974 TI - Letter: Pneumococcus with increased resistance to penicillin. PMID- 4136976 TI - Letter: Preparing multiple doses of bleomycin sulfate. PMID- 4136975 TI - Letter: Polyploidal giant cells in a laryngeal biopsy. PMID- 4136977 TI - Letter: Prevention of deep-vein thrombosis. PMID- 4136978 TI - Letter: Prolactin and migraine. PMID- 4136979 TI - Letter: Prolactin and the immune response. PMID- 4136980 TI - Letter: Propranolol in Parkinson's disease. PMID- 4136981 TI - Letter: Prostaglandins and pre-eclampsia. PMID- 4136982 TI - Letter: Protein requirements. PMID- 4136983 TI - Letter: Pseudomembranous colitis associated with clindamycin. PMID- 4136984 TI - Letter: Pulsus paradoxus in asthma. PMID- 4136985 TI - Letter: Radioimmunoassay of alpha-fetoprotein in gastrointestinal diseases. PMID- 4136986 TI - Letter: Rapid assay of gentamicin. PMID- 4136987 TI - Letter: Recovery from hemianopia in man: evidence for collicular vision? PMID- 4136988 TI - Letter: Relief of action myoclonus by 5-hydroxytryptophan. PMID- 4136989 TI - Letter: Retrolental fibroplasia. PMID- 4136990 TI - Letter: Rifampicin in co-oncogenic experiments. PMID- 4136991 TI - Letter: Rosetting cells in autoimmune haemolytic anaemia. PMID- 4136993 TI - Letter: S.I. units. PMID- 4136992 TI - Letter: Rubella antibody titres in rheumatoid arthritis. PMID- 4136994 TI - Letter: Schistosomes in Vietnam. PMID- 4136995 TI - Letter: Seasonal variation of histological osteomalacia in femoral-neck fractures. PMID- 4136996 TI - Letter: Serum-cholesterol after renal transplantation. PMID- 4136997 TI - Letter: Serum-ferritin. PMID- 4136998 TI - Letter: Serum-gentamicin levels after intravenous bolus injection. PMID- 4136999 TI - Letter: Small doses of insulin in the treatment of diabetic "coma". PMID- 4137000 TI - Letter: Somatic-cell mutation and cancer. PMID- 4137001 TI - Letter: Splenic lymphocytes in chronic myeloid leukaemia. PMID- 4137002 TI - Letter: Staining techniques. PMID- 4137003 TI - Letter: Stereotaxy for obesity. PMID- 4137004 TI - Letter: Subcutaneous heparin and postoperative thromboembolism. PMID- 4137005 TI - Letter: Subnormality and psychiatry. PMID- 4137006 TI - Letter: Synthesis of high-molecular-weight antihaemophilic factor in von Willebrand's disease. PMID- 4137007 TI - Letter: T and B cells in human spleen. PMID- 4137009 TI - Letter: Telling the parents. PMID- 4137008 TI - Letter: T lymphocytes in infectious mononucleosis. PMID- 4137010 TI - Letter: Terminology in biliary radiology. PMID- 4137011 TI - Letter: Thanatophoric dwarfism in triplets. PMID- 4137012 TI - Letter: The bran hypothesis. PMID- 4137013 TI - Letter: The bran-hypothesis. PMID- 4137014 TI - Letter: The cons of group psychotherapy. PMID- 4137015 TI - Letter: The empty sella. PMID- 4137016 TI - Letter: The megavitamin scene. PMID- 4137017 TI - Letter: The Feulgen reaction in polyvinyl alcohol or polyethylene glycol solution. "Fixation" by excluded volume. PMID- 4137018 TI - Letter: Thyrotrophin-releasing hormone in depression. PMID- 4137019 TI - Letter: Transfusion of fresh blood in the newborn period. PMID- 4137020 TI - Letter: Transfusion of fresh blood in the newborn. PMID- 4137021 TI - Letter: Translocation of intrauterine contraceptive devices. PMID- 4137022 TI - Letter: Treatment of cystic fibrosis. PMID- 4137023 TI - Letter: Treatment of haemophilia. PMID- 4137024 TI - Letter: Treatment of paracetamol overdosage. PMID- 4137025 TI - Letter: Undergraduate training in occupational medicine. PMID- 4137026 TI - Letter: Undergraduate training in occupational medicine. PMID- 4137027 TI - Letter: Unsaturated fatty acids and renal transplantation. PMID- 4137028 TI - Letter: Urea treatment of skin malignancies. PMID- 4137029 TI - Letter: Varicose veins in tropical Africa. PMID- 4137030 TI - Letter: Varicose veins in tropical Africa. PMID- 4137031 TI - Letter: Vibrio parahaemolyticus. PMID- 4137032 TI - Letter: Virus particles in acute gastroenteritis. PMID- 4137033 TI - Letter: Visceral malignancy and non-grey hair. PMID- 4137034 TI - Letter: Vitamin B 6, depression, and oral contraception. PMID- 4137035 TI - Letter: Weather and myasthenic fatigue. PMID- 4137036 TI - Letter: Wrinkling of skin in cystic fibrosis. PMID- 4137037 TI - Letter: X long-arm deletion with features of Turner's syndrome. PMID- 4137038 TI - Letters: Comment on Solcia and Buffa's "Azo coupling of indole-reactive enterochromaffin cells". PMID- 4137039 TI - Liberation of vasoactive materials from mast cells in anaphylactic shock. PMID- 4137040 TI - Light and electron microscopy of the islets of langerhans of the ground squirrel (Citellus citellus). PMID- 4137041 TI - Liquid scintillation radioassay in disposable microcentrifuge tubes: radioimmune precipitates and other applications. AB - A simple, economical radioassay system employing disposable polypropylene microcentrifuge tubes was developed. Plastic adapters permitted automatic operation in liquid scintillation spectrometers. Counting efficiencies of (3)H, (14)C, (32)P, and (125)I in liquid scintillation cocktails and of (32)P by Cerenkov radiation (at lower efficiency in absence of added scintillator) were comparable to those in standard vials. Multipurpose use of the microtubes made the system versatile and expedient, e.g., collection of precipitates and radioassay in the same container. Collection of radioimmune precipitates was aided by a carrier inorganic precipitate, Mg(2)P(2)O(7). PMID- 4137042 TI - Liver-cell adenomas and peliosis hepatis in mice associated with oxazepam. PMID- 4137043 TI - Loss of epithelial blood group antigen-A during wound healing in oral mucous membrane. PMID- 4137044 TI - Lymph node function and lymphocyte circulation in the pig. PMID- 4137045 TI - Lymphadenopathy simulating the malignant lymphomas. PMID- 4137046 TI - Lymphocyte differentiation in the chicken embryo--relationship to the microenvironment. PMID- 4137047 TI - Lymphocytes sensitised to basic encephalitogen in patients with multiple sclerosis unresponsive to steroid therapy. PMID- 4137048 TI - Lysogeny and lysosensitivity in Shigella dysenteriae group of bacteria. 3. Serological specificity of receptors of T2 and T4 phages in Shigella dysenteriae 7, strain D7. PMID- 4137049 TI - Macrophages bearing hapten-carrier molecules as foci inducers for T and B lymphocyte interaction. PMID- 4137050 TI - Maintenance of adult rhesus monkey motor neurons in tissue culture. PMID- 4137051 TI - Maintenance of synaptic membranes by the fast axonal flow. PMID- 4137052 TI - Malignant disease of the lymphoid system in immunological perspective. PMID- 4137053 TI - Management of childhood leukemia. PMID- 4137054 TI - Management of terminal illness. PMID- 4137055 TI - Managing carcinoma of the bladder. PMID- 4137056 TI - Marrow adipose cells. Ultrastructural and histochemical characterization. PMID- 4137058 TI - Mechanism of antigen binding to receptor antibody in B cell immunity and tolerance in vitro. PMID- 4137057 TI - Measurement of circulating desialylated glycoproteins and correlation with hepatocellular damage. AB - Addition of increasing amounts of (125)I-labeled desialylated thyroxine-binding globulin (DTBG) to hepatic cell membranes resulted in a progressive increase in binding. Saturability of membrane sites was indicated by a concentration beyond which further increases in [(125)I]DTBG resulted in no further binding. The binding curve for [(125)I]DTBG was similar to binding curves of desialylated orosomucoid, fetuin, and ceruloplasmin. An inhibition assay system using hepatic cell membranes showed that desialylated orosomucoid had a greater affinity for membrane binding sites than did DTBG but desialylated fetuin and ceruloplasmin bound less avidly than DTBG. Serum from normal persons and patients with a variety of illnesses was tested for its ability to inhibit [(125)I]DTBG binding. The inhibitory activity of 1 ml of normal serum was equivalent to that of 0.2-2 mug DTBG. Patients with Laennec's cirrhosis, biliary cirrhosis, and hepatic metastases had greatly increased inhibitory activity in their serum. Patients with jaundice due to extrahepatic obstruction had inhibitory activity not significantly different from that found in normal serum. Column chromatography of normal serum on Sephadex G-200 resulted in inhibitory activity throughout the range of protein molecular weight. Desialylation of normal serum with neuraminidase enhanced the inhibitory activity but did not change the distribution of the activity. Gel chromatography of cirrhotic serum showed markedly increased inhibitory activity associated with the macroglobulins and the 4.5S peak and a new peak of inhibitory activity in the low molecular weight area was also seen. Inhibition of desialylated glycoprotein binding to liver cell membranes by serum from patients with hepatocellular disease raises the possibility that desialylated serum glycoproteins accumulate in the circulation and that patients with compromised hepatocellular function may no longer be able to clear them from the circulation. Alternatively, accumulation of desialylated glycoproteins in the circulation could result from defective protein synthesis by the diseased liver. PMID- 4137059 TI - Mediators of cellular hypersensitivity and immunity including immunologically specific factors. PMID- 4137060 TI - Membrane antigens characteristic of human lymphoid cells in established cultures. PMID- 4137061 TI - Microfluorometric analysis of deoxyribonucleic acid replication kinetics and sister chromatid exchanges in human chromosomes. PMID- 4137062 TI - Micropolygyria: a histopathological and biochemical study. PMID- 4137063 TI - Modulation of the immunological release of the eosinophil chemotactic factor of anaphylaxis from human lung. PMID- 4137064 TI - Molecular evidence for viral agents in human cancer and its chemotherapeutic consequences. PMID- 4137065 TI - Molecular organization in bacterial cell membranes. 3. Components of a "soluble" fraction obtained by n-butanol extraction of Streptomyces albus membranes. PMID- 4137066 TI - Molecular-weight estimates of milk-fat-globule-membrane protein-sodium dodecyl sulphate complexes by electrophoresis in gradient acrylamide gels. AB - The molecular weights of milk-fat-globule-membrane proteins solubilized in sodium dodecyl sulphate were estimated by gradient gel electrophoresis. Standard curves were calibrated from both protein and glycoprotein markers of known molecular weight. Six major proteins were observed with Coomassie Blue staining and six with periodic acid-Schiff staining. The behaviour of the membrane proteins and the marker proteins was compared on several different single strength sodium dodecyl sulphate-polyacrylamide gels between 3 and 12% (w/v). The results were used to calculate the free electrophoretic mobility and retardation coefficient of each protein. Glycoprotein markers had a significantly lower mean free electrophoretic-mobility value than the protein markers. Three of the milk-fat globule-membrane glycoproteins were shown to be independent of any of the Coomassie Blue-stained bands. On the basis of a comparison of the free electrophoretic-mobility and retardation- coefficient values of markers and unknown proteins the most appropriate standard curve for molecular-weight estimation was chosen. PMID- 4137068 TI - Morphologic identification of microperfused-fixed single nephrons during renal micropuncture. PMID- 4137067 TI - Monoamine oxidase and cerebral uptake of dopaminergic drugs. AB - The brain uptake of amines that do not enter the brain or enter it poorly was promoted by noncompetitive inhibitors of monoamine oxidase, as shown by behavioral and chemical criteria. Mice pretreated with water or enzyme inhibitors other than those mentioned were placid after receiving dopamine (3,4 dihydroxyphenethylamine). Mice pretreated with monoamine oxidase inhibitors (nialamide or iproniazid) showed upon treatment with dopamine the brisk motor responses characteristic of treatment with its precursor, L-dopa (3,4 dihydroxyphenylalanine). After receiving dopamine, intact nialamide-pretreated mice showed marked increases of brain dopamine, in contrast to water-pretreated test mice or water-treated controls. In unilaterally caudectomized, nialamide pretreated mice, dopamine induced marked lateral curving of the body toward the lesion followed by running in that direction. Noradrenaline or adrenaline induced curving in caudectomized mice, whereas intact ones remained placid.These catecholamines are bound and inactivated by monoamine oxidase. The cerebral uptakes of chemicals that are bound but not inactivated by monoamine oxidase were thereafter tested. Nialamide induced increased behavioral responses to apomorphine and to N-propyl noraporphine, increased cerebral concentrations of both, and a deep coloration of the brain from methylene blue (bound by monoamine oxidase) but not Evans blue (bound by albumin). Even large doses of nialamide, however, failed to affect the behavioral responses to oxotremorine, which has cholinergic rather than adrenergic or dopaminergic properties. Mitochondrial monoamine oxidase seems therefore to play a specific regulatory role in the transport of substances that it binds, either to inactivate or to release them. PMID- 4137069 TI - Morphological study of the human ovary and mammary gland under the long-term effect of progestational agents. PMID- 4137070 TI - Mucin histochemistry of mucous carcinomas of breast and colon and non-neoplastic breast epithelium. AB - Although epithelial mucin has been demonstrated in ordinary mammary duct carcinomas, it is formed profusely in the uncommon mucous carcinomas. A histochemical study of mucous carcinomas of the breast and colon showed that both types produce similar mucins, viz, acid and neutral, although the mammary carcinomas produce more neutral mucin and small amounts of sulphated mucins are produced by colonic tumours. Similar studies on sections of normal breast and cystic mammary dysplasia have shown that intracellular neutral mucin was present in the ducts and lobules, and that intracellular acid mucin was present within cells of the terminal ducts and lobules. It was demonstrated enzymatically that the acid mucins produced by the normal and neoplastic tissues is sialic acid. Hence it can be shown that the mucin produced by mucous carcinomas is of epithelial rather than connective tissue type. It is contended that mucous carcinoma of breast arises by metaplasia of duct cells that have already undergone malignant change and not from the lobules of the breast. PMID- 4137071 TI - Myelin basic proteins. PMID- 4137073 TI - Nail growth: 30 years of observation. PMID- 4137072 TI - Myopathy associated with pigmentary degeneration of the retina and high protein content of cerebrospinal fluid. PMID- 4137074 TI - Naphthyl phosphates as substrates for fructose 1,6-diphosphatase. PMID- 4137075 TI - Native and artificial energy conserving sites operating in coupled electron donor systems for photosystem II. PMID- 4137076 TI - Natural history of autoimmune achlorhydric atrophic gastritis. A 1-15-year follow up study. PMID- 4137077 TI - Natural history of hypertension. A case for selective non-treatment. PMID- 4137078 TI - Naturally occurring arterial lesions in New World primates. PMID- 4137079 TI - Neurotoxicological effect of small quantities of lindane. Animal studies. PMID- 4137080 TI - New aspects of histaminopexy. PMID- 4137081 TI - New assessment centre for children. PMID- 4137082 TI - Nile blue staining of cells in amniotic fluid for fetal maturity. I. A reappraisal. PMID- 4137083 TI - Nile blue staining of cells in amniotic fluid for fetal maturity. II. In complicated obstetric cases. PMID- 4137084 TI - No evidence for an immunological cross-reaction between encephalitogenic myelin basic protein and histones. PMID- 4137085 TI - No-effect levels of organochlorine pesticides based on induction of microsomal liver enzymes in short-term toxicity experiments. PMID- 4137086 TI - Nuclear images of cells in different functional states. PMID- 4137088 TI - Obituary. Rupert Samuel Bruce Pearson. PMID- 4137087 TI - Nutrition and immunological responsiveness. T-cell function in the offspring of lipotrope and protein-deficient rats. PMID- 4137090 TI - On the immunological properties of preserved tissues. PMID- 4137089 TI - On the diagnosis of rare paraproteins. PMID- 4137091 TI - On the mechanism of interferon induction by polynucleotides. Suppressive effect of poly(rI)--poly(rC) on the liberation of histamine by polycations. PMID- 4137092 TI - On the regeneration and repair of superficial wounds in the skin of Rita rita (Ham.) (Bagridae, Pisces). PMID- 4137093 TI - On the triggering mechanism of anaphylactic reactions in rat mast cells. PMID- 4137094 TI - On the 3 alpha-hydroxysteroid dehydrogenase from Pseudomonas testosteroni. Purification and properties. PMID- 4137095 TI - Oncocognitive autoimmunity. PMID- 4137096 TI - Organization of the invading lymphoid tissue in human lymphoid thyroiditis. PMID- 4137097 TI - Pacemaker treatment. I. Indications for cardiac pacing and patient survival. PMID- 4137098 TI - Partial trisomy 8: further observation of a familial C-G translocation chromosome identified by the Q-staining methods. PMID- 4137099 TI - Participation of endogenous vasoactive agents in the pathogenesis of endotoxin shock. PMID- 4137100 TI - Participation of lipopolysaccharide genes in the determination of the enterobacterial common antigen: analysis of R mutants of Salmonella minnesota. AB - A series of R (rough) Salmonella minnesota mutants with rfb, rfe, and rfa mutations leading to various defects in the biosynthesis of cell wall lipopolysaccharide was analyzed as to their enterobacterial common antigen (CA) content. All mutants that had functional rfe genes were CA(+) as is the wild-type parent. This includes mutants with the most defective lipopolysaccharide core types, demonstrating that core structures are not a necessary part of CA. All rfe(-) mutants (complete lipopolysaccharide core, defective synthesis of O side chains) were defective in the synthesis of CA. A smooth strain was accidentally found to be CA(-); the mutation responsible for this defect was also located, like rfe, very close to ilv. PMID- 4137101 TI - Pathogenesis of membranous glomerulonephritis. PMID- 4137102 TI - Periodic acid-Schiff reaction, a useful index of duration of complete remission in acute childhood lymphocytic leukemia. PMID- 4137103 TI - Pesticide stability in cold-stored plant parts, soils, and dairy products, and in cold-stored extractives solutions. PMID- 4137104 TI - Phosphorylation of rat liver nuclear acidic phosphoproteins after administration of alpha-1,2,3,4,5,6-hexachlorocyclohexane in vivo. PMID- 4137105 TI - Phototransduction mutants of Drosophila melanogaster. PMID- 4137107 TI - Pick's disease. Histological and clinical correlations. PMID- 4137106 TI - Physiological and morphological identification of hypothalamic magnocellular neuroendocrine cells in goldfish preoptic nucleus. AB - 1. Intracellular recordings were made from antidromically identified neurones in the goldfish preoptic nucleus and Procion Yellow was ejected from the recording pipette, marking these magnocellular neuroendocrine cells diffusely, for histological identification.2. In confirmation of earlier studies these preoptic neuroendocrine cells showed resting membrane potentials of 47 mV, action potentials up to 85 mV, action potentials of long duration (3.9 msec) occurring in two steps, long-lasting hyperpolarizing after-potentials and orthodromic driving from olfactory input.3. Magnocellular neuroendocrine cells exhibited all or-none jumps to shorter antidromic latencies as pituitary stimulus strength increased, suggesting multiple branching of the ;axones' either near the preoptic nucleus or within the neural lobe.4. I find three morphological types of neuroendocrine cells throughout the magnocellular part of the preoptic nucleus. Cell Type I is a large (37 mum), multipolar neurone, 48 mum from the ependyma, with fine ;dendrites' projecting into the lateral hypothalamus and within the preoptic nucleus, with multiple branched ;axones'. Cell Type II is a large (31 mum), multipolar neurone, 24 mum from the ependyma, with a coarse ;dendrite' to the ependyma and fine ;dendrites' within the preoptic nucleus, with limited ;axonal' branching. Cell Type III is a small (18 mum), multipolar neurone, 46 mum from the ependyma, with fine ;dendritic' processes distributed within the preoptic nucleus, with limited ;axonal' branching.5. I conclude that magnocellular neuroendocrine cells show electrical membrane properties of other central neurones with both physiological and morphological evidence for multiple ;axonal' branching. The three identifiable neuroendocrine cell types (I, II, III) are distributed widely within the anatomical limits of the preoptic nucleus, pars magnocellularis, with each type receiving ;specific' input connexions and with unique output pathways. I suggest that these three types of neuroendocrine cells may be related to the ;cellular' secretion of ;specific' neurohypophysial hormones and neurophysins. PMID- 4137108 TI - Placental free-fatty-acid transfer and fetal adipose-tissue development: an explantation of fetal adiposity in infants of diabetic mothers. PMID- 4137109 TI - Polychlorinated biphenyl-induced alteration of biologic parameters in the rat. PMID- 4137110 TI - Positive occipital sharp transients of sleep: relationships to nocturnal sleep cycle in man. PMID- 4137111 TI - Possibilities now available in the study of the Y chromosome in human cells. PMID- 4137112 TI - Possible role of lymphokines in the development of ectopic lymphoid foci in the chicken. PMID- 4137113 TI - Postoperative course of vesicoureteral reflux associated with benign obstructive prostatic disease. PMID- 4137114 TI - Pour-on insecticides for the control of cattle lice (Linognathus vituli and Damalinia bovis). PMID- 4137115 TI - Predictive value of ST-segment displacement and other indices after myocardial infarction. PMID- 4137116 TI - Preferential location of chlorambucil-induced breakage in the chromosomes of normal human lymphocytes. PMID- 4137117 TI - Pregnancy following autograft transplantation of Fallopian tube and ovary in the rabbit. PMID- 4137118 TI - Preparation of clinical gynecologic specimens for automated analysis. An overview. PMID- 4137119 TI - Preparation of RNA transcripts of discrete segments of DNA. PMID- 4137120 TI - Preparation, characterization, and activation of a highly purified factor XI: evidence that a hitherto unrecognized plasma activity participates in the interaction of factors XI and XII. PMID- 4137121 TI - Presumptive Y-15 translocation and mental retardation in a family with a case of Klinefelter's syndrome. PMID- 4137122 TI - Prevention and treatment of carbon tetrachloride hepatotoxicity by cysteine: studies about its mechanism. PMID- 4137124 TI - Procedure re-examined. PMID- 4137123 TI - Primate type-C virus-related reverse transcriptase and RNA in human acute leukemia cells as potential diagnostic markers. PMID- 4137125 TI - Proceedings: Blockage of axoplasmic transport. Its relationships with the trophic function of neurons. PMID- 4137126 TI - Proceedings: Bulgarian section for EEG and clinical neurophysiology. PMID- 4137127 TI - Proceedings: Carcinoma of the oral cavity--general principles of therapy. PMID- 4137128 TI - Proceedings: Eastern Association of Electroencephalographers. PMID- 4137129 TI - Proceedings: Neurotrophic control of skeletal muscle of the rat. PMID- 4137130 TI - Proceedings: Neurotrophic effects in relation to axoplasmic transport. PMID- 4137131 TI - Proceedings: Polyclonal gammopathy and lymphoproliferation after transfer factor in severe combined immunodeficiency disease. PMID- 4137133 TI - Proceedings: The EEG society. PMID- 4137132 TI - Proceedings: The effect of methoxy-derivatives of catecholamines on histamine release from sensitized human leucocytes and its inhibition by the parent compounds. PMID- 4137134 TI - Proflavin-chymotrypsin interaction: high pressure temperature-jump studies. PMID- 4137135 TI - Progress with antiviral agents. PMID- 4137136 TI - Prolymphocytic leukaemia. PMID- 4137137 TI - Properties of factor 8 (antihemophilic factor). PMID- 4137138 TI - Proportional mortality among vinyl-chloride workers. PMID- 4137139 TI - Prospective, controlled trial of cyclophosphamide therapy in children with nephrotic syndrome. Report of the International study of Kidney Disease in Children. PMID- 4137140 TI - Prostaglandin E2 and the stimulation of rat gastric acid secretion by dibutyryl cyclic 3',5'-AMP. PMID- 4137141 TI - Protein phosphokinase activity in horse thyroid nuclei. PMID- 4137142 TI - Protothecosis: a case of disseminated algal infection. PMID- 4137143 TI - Proximal skin necrosis after radial-artery cannulation. PMID- 4137144 TI - Pseudoxanthoma elasticum: dermal polyanions and the mineralization of elastic fibers. PMID- 4137145 TI - Purification and detection of reverse transcriptase in viruses and cells. PMID- 4137146 TI - Purification and properties of nitrate reductase from Escherichia coli K12. PMID- 4137147 TI - Purification of human C3 proactivator by affinity chromatography. PMID- 4137148 TI - Purification of the RNA-directed DNA polymerase from avian myeloblastosis virus and its assay with polynucleotide templates. PMID- 4137149 TI - Purification, composition, and serological characterization of histoplasmin-H and M antigens. AB - To obtain purified H and M antigens suitable as primary standards in the serological diagnosis of histoplasmosis by agar gel double-diffusion tests, H and M reactive components of histoplasmin were fractionated by column chromatography by using Sephadex G-100, Sephadex G-200, and diethylaminoethyl cellulose. Six fractions from diethylaminoethyl cellulose were reactive in agar gel double diffusion, complement fixation, and capillary precipitin tests. When examined by electrophoresis on acrylamide gel, one M antigen (fraction 2, molecular weight greater than 200,000) and two H antigens (fractions 5 and 6, molecular weight greater than 200,000) each gave essentially a single protein band. In agar gel double-diffusion and complement fixation tests with sera from patients with proven cases of histoplasmosis, blastomycosis, or coccidioidomycosis, these two fractions of H antigen and the one of M antigen reacted only with sera from proven or suspect cases of histoplasmosis and showed reactivity with those sera known to contain only the anti-H or anti-M antibody, respectively. Fraction 2 (M antigen) and fractions 5 and 6 (H antigens) had carbohydrate-to-protein ratios of 1.60, 0.77 and 0.78, respectively. Both antigens contained galactose, glucose, mannose, and hexosamine, with mannose being the predominant sugar. Fraction 2 was characterized by a high proline and glucose content, whereas fractions 5 and 6 contained higher concentrations of galactose, mannose, glycine, and alanine. Each of these products appeared to separate into two active fractions, one of a molecular weight greater than 200,000 and one of a molecular weight less than 35,000. The M antigen component of fraction 2 was still characterized by a high proline content, whereas the H antigen components of fractions 5 and 6 had a high content of glutamic acid, serine, glycine, and proline. PMID- 4137150 TI - Qualitative vitamin requirements of Oryzaephilus mercator fauvel and their deficiency effects on the survival and growth of F1-progeny. PMID- 4137151 TI - Quantitative bone scanning: a method for assessing response of bone metastases to treatment. PMID- 4137152 TI - Quantitative determination of secondary amines: measurement of N-methylalanine. PMID- 4137153 TI - Quantity of serum immunoglobulins IgG, IgA and IgM in Bulgarian blood-donors. PMID- 4137154 TI - Radial and axial gradients of lead concentration in bark and xylem of hardwoods. PMID- 4137155 TI - Radioisotopes in preliminary screening of cervical cancer. PMID- 4137156 TI - Radiozinc uptake and scintiscanning in prostatic disease. PMID- 4137157 TI - Rapid analysis of dichloran, lindane, PCNB and TCNB residues in lettuce by automated gas-liquid chromatography. PMID- 4137158 TI - Rapid fractionation technique and re-treatment of cerebral metastases by irradiation. PMID- 4137159 TI - Reciprocating supraventricular tachycardia initiated by paired premature beats. PMID- 4137160 TI - Reconstructive operations on mandible in children. (Clinico-experimental study). PMID- 4137161 TI - Red cell hydrolases. 3. Neuraminidase activity in isolated human erythrocyte plasma membranes. PMID- 4137162 TI - Reduction in circulating T lymphocytes in alcoholic liver disease. PMID- 4137163 TI - Regulation of expression of a cistron in the RNA bacteriophage MS2. PMID- 4137164 TI - Relation between viruses from acute gastroenteritis of children and newborn calves. PMID- 4137165 TI - Relationship between Epstein-Barr virus (EBV) DNA and the EBV-determined nuclear antigen (EBNA) in Burkitt lymphoma biopsies and other lymphoproliferative malignancies. PMID- 4137166 TI - Release of histamine from human skin induced by intracutaneous injection of adenosine-5'-triphosphate. PMID- 4137167 TI - Remnants of necrotic grey matter. PMID- 4137168 TI - Replantation of composite graft of the nasal ala, Case report. PMID- 4137169 TI - Respiratory mast cells and basophiloid cells. II. Effect of pharmocologic agents on 3'5'-adenosine monophosphate content and on antigen-induced histamine release. PMID- 4137170 TI - Reverse transcriptase activity: increase in marrow cultures from leukaemic patients in relapse and remission. AB - An enzyme activity with the characteristics of reverse transcriptase was detected in marrow from patients with leukaemia in relapse and in firm haematological remission. The endogenous enzyme activities increased following culture, and in remission patients the enzyme activities reached levels equal to or exceeding those found in relapse. PMID- 4137171 TI - Reye's syndrome due to a novel protein-tolerant variant of ornithine transcarbamylase deficiency. PMID- 4137172 TI - Rhinophyma experiences with 81 operated patients. PMID- 4137173 TI - Role of hepatitis-B antigen carriers in non-parenteral transmission of the hepatitis-B virus. PMID- 4137174 TI - RNA-dependent DNA polymerase and ribonuclease H from Friend virions. PMID- 4137175 TI - RNA-dependent DNA polymerase from avian myeloblastosis virus. PMID- 4137176 TI - Sa 1, a possible new HL-A specificity found in the Japanese population. PMID- 4137178 TI - Scientific medicine? PMID- 4137177 TI - Salivary gland rests in the human pituitary. Light and electron microscopical study. PMID- 4137179 TI - Seasonal variation of histological osteomalacia in femoral-neck fractures. PMID- 4137180 TI - Selective photoconvulsive responses to intermittent diffuse and patterned photic stimulation. PMID- 4137181 TI - Senile cardiac amyloidosis in the dog. PMID- 4137182 TI - Senile changes in the fine structure of the lens in the rudd(Scardinius eryopthalmicus). PMID- 4137183 TI - Sensitization of human lymphocytes against autologous or allogeneic lymphoblastoid cell lines: characteristics of the reactive cells. PMID- 4137184 TI - Sensori-motor stimulation for the young handicapped child. PMID- 4137185 TI - Separation and characterization of cortical and medullary bursal lymphocytes. PMID- 4137186 TI - Sequential study of the impairment of thyroid function in the early stage of subacute thyroiditis. PMID- 4137187 TI - Serology for automated cytotoxicity assays. Contrast fluorescence test. PMID- 4137188 TI - Severe endemic trachoma in tunisia. II. A controlled therapy trial of topically applied chlortetracycline and erythromycin. PMID- 4137189 TI - Alpha(1)-fetoprotein in chronic liver disease. PMID- 4137190 TI - Simian sarcoma and feline leukemia virus antigens: isolation of species- and interspecies-specific proteins. PMID- 4137191 TI - Simultaneous differential staining by a cationic carbocyanine dye of nucleic acids, proteins and conjugated proteins. I. Phosphoproteins. PMID- 4137192 TI - Simultaneous differential staining by a cationic carbocyanine dye of nucleic acids, proteins and conjugated proteins. II. Carbohydrate and sulfated carbohydrate-containing proteins. PMID- 4137193 TI - Soluble-complex formation after myocardial infarction. PMID- 4137194 TI - Some aspects of sodium transport in chicken erythrocytes. PMID- 4137196 TI - Some plastic operations in ophthalmology with use of sterilized homologous tissues. PMID- 4137195 TI - Some observations upon developmental dyslexia. PMID- 4137197 TI - Some practical aspects of the transfer of passive immunity to newborn foals. PMID- 4137198 TI - Some psychoanalytic condiserations of bull fighting and bull worship. PMID- 4137199 TI - Some questions of static tissue conservation theory. PMID- 4137200 TI - Some thoughts on nursing inservice education. PMID- 4137201 TI - Species responsible for the fluorescence of 1:N6-ethenoadenosine. PMID- 4137202 TI - Specificity of hapten-reactive T and B mouse lymphocytes. Affinity and avidity of T- and B-cell receptors and anti-hapten antibodies as factors of dose and time after immunization. PMID- 4137203 TI - Specificity of receptors for IgG on human lymphocyte-like cells. PMID- 4137204 TI - Spectral matching of classical cytochemistry to automated cytology. PMID- 4137205 TI - Status quo in flow-through cytometry. PMID- 4137206 TI - Structural and functional properties of blood monocytes cultured in vitro. PMID- 4137207 TI - Structural change with pH of native beta-lactoglobulin A and B and of their derivatives with mercurinitrophenols as deduced from circular dichroic spectra. PMID- 4137208 TI - Structural changes in chromaffin granules induced by divalent cations. PMID- 4137209 TI - Studies of cochlear vasculature and sensory structures: a modified method. PMID- 4137210 TI - Studies of the direct coloring thiocholine method for localizing cholinesterase activity. PMID- 4137211 TI - Studies on passive immunity in the foal. 1. Gamma-globulin and antibody variations associated with the maternal transfer of immunity and the onset of active immunity. PMID- 4137212 TI - Studies on the binding and phagocytic inhibition properties of antimacrophage globulin (AMG). PMID- 4137213 TI - Studies on the inhibition of C56 initiated lysis (reactive lysis). I. Description of the phenomenon and methods of assay. PMID- 4137214 TI - Subacute toxicity of methylmercury in the adult cat. PMID- 4137215 TI - Subcellular structure of bovine thyroid. VI. A study of bovine thyroid nuclei by density gradient centrifugation in a zonal A-XII rotor. PMID- 4137216 TI - Submucous cleft palates. PMID- 4137217 TI - Successful laboratory screening for congenital hypothyroidism. PMID- 4137218 TI - Summary: the infant at risk--early detection and preventive intervention. PMID- 4137219 TI - Superficial macromolecular arrays on the cell wall of Spirillum putridiconchylium. AB - Electron microscopy of the cell envelope of Spirillum putridiconchylium, using negatively stained, thin-sectioned, and replicated freeze-etched preparations, showed two superficial wall layers forming a complex macromolecular pattern on the external surface. The outer structured layer was a linear array of particles overlying an inner tetragonal array of larger subunits. They were associated in a very regular fashion, and the complex was bonded to the outer, pitted surface of the lipopolysaccharide tripartite layer of the cell wall. The relationship of the components of the two structured layers was resolved with the aid of optical diffraction, combined with image filtering and reconstruction and linear and rotary integration techniques. The outer structural layer consisted of spherical 1.5-nm units set in double lines determined by the size and arrangement of 6- by 3-nm inner structural layer subunits, which bore one outer structural layer unit on each outer corner. The total effect of this arrangement was a double-ridged linear structure that was evident in surface replicas and negatively stained fragments of the whole wall. The packing of these units was not square but skewed by 2 degrees off the perpendicular so that the "unit array" described by optical diffraction and linear integration appeared to be a deformed tetragon. The verity of the model was checked by using a photographically reduced image to produce an optical diffraction pattern for comparison with that of the actual layers. The correspondence was nearly perfect. PMID- 4137220 TI - Suppression of immunological memory for a cross-reactive idiotype in adult mice. PMID- 4137221 TI - Surface antigens of murine IgM and IgG forming cells. PMID- 4137222 TI - Surgical correction of alopecia;. PMID- 4137223 TI - Susceptibility of rats to palmotoxins Bo and Go. PMID- 4137224 TI - Suxamethonium--a review. Pharmacological actions of suxamethonium apart from its neuromuscular blocking effect. PMID- 4137225 TI - Synaptic macromolecules: identification and metabolism. PMID- 4137226 TI - Synthetic vaccines--a dream or reality. PMID- 4137227 TI - Systemic anaphylaxis in the human being. PMID- 4137228 TI - Systemic lupus erythematosus. PMID- 4137229 TI - T cell recognition of cell surface antigens. I. Specificity. PMID- 4137230 TI - Teaching blood morphology: audiovisual method compared to microscope slides with written text and instructor. PMID- 4137231 TI - Techniques applicable to computer-aided cytophotometry in virology. PMID- 4137232 TI - Techniques of open prostatectomy. PMID- 4137233 TI - Temperature and weather correlates of myasthenic fatigue. PMID- 4137234 TI - Temperature effect on the permeability of plasma membranes of advanced germinal cells of the rat testis. PMID- 4137235 TI - Template specificities of Xenopus laevis RNA polymerases. Selective transcription of ribosomal cistrons by RNA polymerase A. PMID- 4137236 TI - Testosterone metabolism in benign prostatic hypertrophy. Suppression by diethylstilbestrol and gestonorone capronate. PMID- 4137238 TI - Textural parameters related to nuclear maturation in the granulocytic leukocytic series. PMID- 4137237 TI - Tests for penicillin allergy in man. I. Carrier effect on response to penicilloyl conjugates. PMID- 4137239 TI - The activity and research programme of the tissue bank in Warsaw. PMID- 4137240 TI - The application of artificial intelligence techniques to biologic cell identification. PMID- 4137241 TI - The argyrophil cells in the pancreatic islets of man. PMID- 4137242 TI - The blue dextran excluded volume of the human erythrocyte membrane. PMID- 4137243 TI - The cellular and molecular biology of RNA tumor viruses, especially avian leukosis-sarcoma viruses, and their relatives. PMID- 4137244 TI - The chemical and immunologic properties of the basic A1 protein of myelin. PMID- 4137245 TI - The chemical nature of the shell of molluscs. I. Prismatic and nacreous layers of a bivalve Lamellidans marginalis (Unionidae). PMID- 4137246 TI - The chemistry and biochemistry of phytanic, pristanic and related acids. PMID- 4137247 TI - The chemotherapy of colorectal cancer. PMID- 4137248 TI - The cytogenetic effect of triethylenemelamine in the rat as evaluated by the micronucleus test. PMID- 4137249 TI - The cytophysiology of thyroid cells. PMID- 4137250 TI - The definition of a lymphocyte-specific alloantigen system in the rat (Ly-1). PMID- 4137251 TI - The diagnosis of systemic lupus erythematosus. PMID- 4137252 TI - The early diagnosis of rejection by the leucocyte migration test in cadaveric renal transplantation. PMID- 4137253 TI - The effect of antigen doses and time intervals between antigen injections on secondary, tertiary and quaternary antibody responses. Establishment of hyperimmunization with bovine serum albumin in mice treated with capsular polysaccharide of Klebsiella pneumoniae. PMID- 4137254 TI - The effect of fixation on staining of placental tissue. PMID- 4137255 TI - The effect of glycoprotein from Candida albicans on isolated rat mast cells. PMID- 4137256 TI - The effect of post-heparin lipolytic activity on plasma lipoproteins. A study by electron microscopy. PMID- 4137257 TI - The effect of sex, social class and parity on achievement of Denver developmental screening test items in the first year of life. PMID- 4137258 TI - The effect of undernutrition on the rate of axonal transport in rabbit vagus nerves. PMID- 4137259 TI - The effect of white noise on the somatosensory evoked response in sleeping newborn infants. PMID- 4137260 TI - The effect of DL-lactate on regulation of porphyrin and heme biosynthesis in Escherichia coli and Achromobacter. PMID- 4137261 TI - The effects of colchicine and lumicolchicine on the rapid phase of axonal transport in the rabbit visual system. PMID- 4137262 TI - The effects of elevated intraocular pressure on slow axonal protein flow. PMID- 4137263 TI - The effects of N-methyl-3 piperidyl benzilate (JB-336) on sleep pattern and spiking activity in the lateral geniculate nucleus. PMID- 4137264 TI - The effects of 5,6-dihydroxytryptamine in the amphibian spinal cord using silver staining techniques. PMID- 4137265 TI - The electronmicroscopy of DNA. PMID- 4137266 TI - The fibrillar proteins of nerve cells. PMID- 4137267 TI - The full thickness skin graft for primary repair of malignant facial tumours. PMID- 4137268 TI - The fusion of hen erythrocytes by lipid-soluble and surface-active immunological adjuvants. PMID- 4137269 TI - The genetics of C-type RNA tumor viruses. PMID- 4137270 TI - The great protein fiasco. PMID- 4137271 TI - The histochemical demonstration of O-acylated sialic acid in gastrointestinal mucins. Their association with the potassium hydroxide-periodic acid-schiff effect. PMID- 4137272 TI - The hormone synthesis of hyperfunctioning thyroid nodules in euthyroid patients. PMID- 4137273 TI - The immune mechanisms and diagnosis of pigeon breeder's disease. PMID- 4137274 TI - The immunoglobulin system of the suckling pig. PMID- 4137275 TI - The infidelity of avian myeloblastosis virus deoxyribonucleic acid polymerase in polynucleotide replication. PMID- 4137276 TI - The influence of d-triiodothyronine (d-T3) on thyrotrophin secretion in man. PMID- 4137277 TI - The interocular distance in children with cleft before the operation. PMID- 4137278 TI - The investigation of superficial fungal infections by skin surface biopsy. PMID- 4137279 TI - The isolation of glyco-alpha-lactalbumins from some ruminant milks. PMID- 4137280 TI - The lack of correlation between hallucinogenesis and inhibition of axoplasmic transport. PMID- 4137281 TI - The leukocyte migration test in atopic dermatitis. PMID- 4137283 TI - The naphthol yellow S stain for proteins tested in a model system of polyacrylamide films and evaluated for practical use in histochemistry. PMID- 4137282 TI - The metabolism of antifertility steroids. The in virto metabolism of chlormadinone acetate. PMID- 4137284 TI - The nitroblue-tetrazolium test following acute myocardial infarction. AB - The percentage nitroblue-tetrazolium (NBT) leucocyte levels were evaluated daily in the 10 days following a first attack of coronary thrombosis. In 12 uncomplicated cases the peak increase was on the second or third day; thereafter the level declined and was below 10% by the tenth day. Three other patients did not conform to this pattern of NBT behaviour. They had experienced a second myocardial infarction and this was attended by a secondary rise in the NBT score; in the two survivors the score remained elevated on the tenth day. Comparison of the score on the second-third and tenth-fourteenth days is a possible useful index of a further complication. PMID- 4137285 TI - The nuclear envelope: its ultrastructure and functional significance. PMID- 4137286 TI - The parenteral toxicity of clindamycin 2-phosphate in laboratory animals. PMID- 4137287 TI - The pathology of the organic dementias. PMID- 4137288 TI - The pharmacodynamics of the oral anticoagulant drugs. PMID- 4137289 TI - The preparation of RNA-directed DNA polymerase from ovaries of Xenopus laevis. PMID- 4137290 TI - The presence of melanocytes in the nasal cavity. PMID- 4137291 TI - The quantimet cytoscreen and the interactive approach to cancer screening. PMID- 4137292 TI - The quaternary structure of alfalfa mosaic virus. PMID- 4137293 TI - The relation of red cell size to fetal hemoglobin concentration in the term infant. PMID- 4137294 TI - The response of the canine heart to double pulses of short duration: a simple addition principle. PMID- 4137295 TI - The role of soluble factors in T-B cell collaboration. PMID- 4137296 TI - The role of targets and mediators in endotoxin shock. PMID- 4137297 TI - The significance of heart-reactive antibodies in heart disease. PMID- 4137298 TI - The significance of Mallory bodies in the progression of fatty liver into cirrhosis. PMID- 4137299 TI - The structure of a morphogenetic cytoplasm, present in the polar lobe of Bithynia tentaculata (Gastropoda, Prosobranchia). PMID- 4137300 TI - The structure of the fibrinogen degradation products. PMID- 4137301 TI - The system bandpass required to avoid distortion of early components when averaging somatosensory evoked potentials. PMID- 4137302 TI - The ultrastructure of cultivable treponemes. 1. Treponema phagedenis, Treponema vincentii and Treponema refringens. PMID- 4137303 TI - The ultrastructure of human mitotic chromosomes and interphase nuclei treated by Giemsa banding techniques. PMID- 4137304 TI - The unlabeled antibody enzyme method of immunocytochemistry. Quantitative comparison of sensitivities with and without peroxidase-antiperoxidase complex. PMID- 4137305 TI - The use of coherent optical processing techniques for the automatic screening of cervical cytologic samples. PMID- 4137306 TI - The use of dimethyl sulfoxide in assessing fertility in turkey eggs. PMID- 4137307 TI - The use of fascial sling for the correction of postprostatectomy incontinence. PMID- 4137308 TI - The use of germ-free piglets in the study of lymphoid tissue and germinal centre formation. PMID- 4137309 TI - The use of protein A-containing Staphylococcus aureus as a solid phase anti-IgG reagent in radioimmunoassays as exemplified in the quantitation of alpha fetoprotein in normal human adult serum. PMID- 4137310 TI - The value of anti-DNA antibody titers in the early diagnosis, treatment and follow-up of systemic lupus erythematosus. PMID- 4137311 TI - The Denver Developmental Screening Test. Achievement of test items in the first year of life by Denver and Cardiff infants. PMID- 4137312 TI - The Hemalog D white cell differential system. PMID- 4137314 TI - The Styx. PMID- 4137313 TI - The Sezary cell: cytologic, cytochemical, and immunologic studies. PMID- 4137315 TI - Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c. PMID- 4137316 TI - Thrombophlebitis. A cardinal symptom of Behcet's syndrome. PMID- 4137317 TI - Thymic dependence of amphibian antibody responses. PMID- 4137319 TI - Thyroid function after injury. PMID- 4137318 TI - Thymus immunoglobulin receptors. Ontogenic development, response to antigenic stimulation and their possible role in the regulation of "aggressive" immune reactions. PMID- 4137320 TI - Thyroid function in a prosimian, Perodicticus potto. PMID- 4137321 TI - Thyroid-stimulating immunoglobulins in Graves' disease. PMID- 4137322 TI - Thyrotrophin-releasing hormone in the treatment of depression. PMID- 4137323 TI - Tissue banks and the problem of transplantation. PMID- 4137324 TI - Tissue reactions after subcutaneous implantation of Hydron Sponge. PMID- 4137326 TI - Total knee replacement. PMID- 4137325 TI - Tonic contraction of calf muscles by non-tetanic stimulation of popliteal nerve in man. PMID- 4137327 TI - Toxic effects of warfarin in rats fed different diets. PMID- 4137328 TI - Toxicologic changes in rats fed graded dietary levels of ochratoxin A. PMID- 4137329 TI - Tracking the dominant frequency of the EEG by phase-locked loop demodulation. PMID- 4137330 TI - Transformation of human fibroblasts with D.N.A. of cultured human rhabdomyosarcoma cells. PMID- 4137331 TI - Transmission of Creutzfeldt-Jakob disease from man to squirrel monkey. PMID- 4137332 TI - Transplantation of homogenous joints. Treatment of homogenous osteocartilaginous graft by partial replacement for autogenous cancellous bone and impregnation with autogenous marrow. PMID- 4137333 TI - Treatment of immediate hypersensitivity reactions to drugs. PMID- 4137334 TI - Treatment of oat-cell carcinoma of bronchus by preoperative radiotherapy and surgery. PMID- 4137335 TI - Tuberculin sensitivity in BCG-vaccinated children with common warts. PMID- 4137336 TI - Tumors formed by human rhabdomyosarcoma cells in chorioallantoic membrane of embryonated hens' eggs. PMID- 4137337 TI - Two propylhexedrine-associated fatalities: Benzedrine revisited. PMID- 4137338 TI - Typing of Haemophilus influenzae by counterimmunoelectrophoresis. PMID- 4137339 TI - Ultrastructural differences along the colonic mucosa of the mouse. PMID- 4137341 TI - Ultrastructure and organization of the bacterial envelope. PMID- 4137340 TI - Ultrastructural evidence for myosin of the smooth muscle type at the surface of trypsin-dissociated embryonic chick cells. PMID- 4137342 TI - Ultrastructure of cells isolated from rabbit aorta. PMID- 4137343 TI - Ultrastructure of freeze-cleaved dermal collagen. PMID- 4137344 TI - Unblocking or activation of the cellular immune mechanism by induced proteolysis in patients with cancer. PMID- 4137346 TI - University of Birmingham educational services unit. PMID- 4137345 TI - Unbuffered osmium staining in pars recta of the proximal tubule from rat kidney studied by thin and semi-thin section cytochemistry. PMID- 4137347 TI - Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders. PMID- 4137348 TI - Use of a spectral ratio in lateralization of CNS lesions. PMID- 4137349 TI - Use of antibiotics in a dairy herd and their effect on resistance determinants in enteric and environmental Escherichia coli. PMID- 4137350 TI - UDPG-glycogen transferase and phosphorylase activities in isolated rat liver parenchymal cells. PMID- 4137351 TI - Vaccinia of the vulva. A case report. PMID- 4137352 TI - Value of new laboratory tests in diagnosis and treatment. PMID- 4137353 TI - Value of the combined cytological and cytochemical classification in the management of acute childhood leukemia. PMID- 4137354 TI - Variation in the pattern of carbonic anhydrase activity in the cells of the gastric glands. PMID- 4137355 TI - Variations in separation-individuation and implications for play ability and learning as studied in the three-year-old in nursery school. PMID- 4137356 TI - Viroimmunoassays: detection of virus-antigen-antibody complexes with an immunoadsorbent. PMID- 4137357 TI - We need medical superintendents. PMID- 4137359 TI - William Gordon Masefield. PMID- 4137358 TI - Whooping-cough vaccination. An assessment. PMID- 4137360 TI - William James McCracken. PMID- 4137361 TI - Yolk sac tumor and alpha-fetoprotein: clinicopathological study of four cases. PMID- 4137362 TI - [Sexual precocity (author's transl)]. PMID- 4137363 TI - "Genetic' transformation of bacteria by RNA and loss of oncogenic power properties of Agrobacterium tumefaciens. Transforming RNA as template for DNA synthesis. PMID- 4137364 TI - in vitro studies on allotype suppression. I. Release from allotype suppression by antibodies specific for the non-suppressed allotype. PMID- 4137365 TI - o-Phthaldialdehyde reactive substances in dog's plasma and gelatin (Haemaccel) complicating the determination of histamine. PMID- 4137366 TI - [A new beta-blocker, LB 46--Visken]. PMID- 4137367 TI - [Ablatio mammae and postoperative radiotherapy of breast carcinoma]. PMID- 4137368 TI - [Action myoclonus occuring during acute decompensation of chronic renal insufficiency (author's transl)]. PMID- 4137369 TI - [Adequate dosage of tetanus antitoxin and tetanus-immune human gamma globulin TIG in the treatment of tetanus]. PMID- 4137370 TI - [Administration of creatine for several days: its effects on increased creatinuria (author's transl)]. PMID- 4137371 TI - [Affinity of 111In-bleomycin for malignant tumors (author's transl)]. PMID- 4137372 TI - [Anatomist Joseph von Gerlach, Erlangen, and his significance in neurohistology]. PMID- 4137373 TI - [Antibody therapy of influenza infections]. PMID- 4137374 TI - [Antihistaminic properties of (quinuclidinyl-3-methyl)-10 phenothiazine in man)]. PMID- 4137375 TI - [Audio-visual service at the Hotel-Dieu du Sacre-Coeur de Jesus]. PMID- 4137376 TI - [Bioenergetics in lung tissue]. PMID- 4137377 TI - [Cardiothyrotoxicoses]. PMID- 4137378 TI - [Cerebral circulatory disorders in acute craniocerebral injuries]. PMID- 4137379 TI - [Characteristics of clinical course and immunology of systemic lupus erythematosus (SLE) in males]. PMID- 4137380 TI - [Chemical pneumonitis following lymphangiography in childhood (author's transl)]. PMID- 4137381 TI - [Chemotherapy of suppurative meningitis]. PMID- 4137383 TI - [Clinical significance of urine cytology. Its present status in urology]. PMID- 4137382 TI - [Clinical and histological diagnosis of a case of familial adult metachromatic leucodystrophy (author's transl)]. PMID- 4137384 TI - [Clinical studies on fetal proteins--especially on alpha 2H globulin (alpha-2H) of Buffe (author's transl)]. PMID- 4137385 TI - [Clinico-immuno-morphological characteristics of the early period of systemic lupus erythematosus]. PMID- 4137386 TI - [Combined effect of radiation and bleomycin on mouse intestinal epithelial cells (author's transl)]. PMID- 4137387 TI - [Combined hormone therapy successfully used in ventricular extrasystole in pituitary dwarfism]. PMID- 4137388 TI - [Comparison of the results of traditional prostatectomy and of immediate prostatectomy without urethral catheter (author's transl)]. PMID- 4137389 TI - [Condition of the intraorgan lymphatic ducts of the trachea in fibro-cavernous pulmonary tuberculosis]. PMID- 4137390 TI - [Conservative treatment of prostatic hypertrophy with gestagens]. PMID- 4137391 TI - [Considerations concerning "antilymphocyte serums"]. PMID- 4137392 TI - [Contribution to the clinical aspects and morphology of successfully treated Whipple's disease]. PMID- 4137393 TI - [Cross resistance of tubercle bacilli to KM, VM, CPM, LVM, and TUM. II. The susceptibility of antibiotic-resistant strains which were obtained in vitro to the five antibiotics (author's transl)]. PMID- 4137394 TI - [Current concepts of chemistry and immunology of amyloid fibrils]. PMID- 4137395 TI - [Current problems in immunology]. PMID- 4137396 TI - [Cytological diagnosis of cancer of the prostate by the luminescence microscopic method]. PMID- 4137397 TI - [Demonstration of bands of human chromosomes in ordinary light and fluorescence after staining with pseudo-isocyanin]. PMID- 4137398 TI - [Doppler ultrasound sonography in the diagnosis of occlusions and stenoses of the carotid arteries with paradoxical or absent neurological findings (author's transl)]. PMID- 4137400 TI - [Effect of lindane on the serotonin content in the blood and tissues of white rats]. PMID- 4137399 TI - [DDT and its metabolites as well as gamma-HCH in the blood, bone marrow and fatty tissue in some hematologic syndromes]. PMID- 4137401 TI - [Effect of malnutrition on brain development (author's transl)]. PMID- 4137402 TI - [Effects of alcohol at the cellular level]. PMID- 4137403 TI - [Egas Moniz, 1874-1955, Nobel-prize winner in medicine and physiology 1949]. PMID- 4137404 TI - [Enzyme-histochemical studies on the reorganization of autologous spleen transplants (author's transl)]. PMID- 4137405 TI - [Evaluation of the degree of atrophy of tissues of the pelvic fundus in women with uterine prolapse]. PMID- 4137406 TI - [Experimental studies on heart contusion]. PMID- 4137407 TI - [Explorative laparotomy with splenectomy in lymphogranulomatosis]. PMID- 4137408 TI - [Factors influencing the value of thyroxine-binding index (TBC index). Possibility of quantifying the variables in order to obtain a "clean" TBC index. Experimental results obtained from the study of the influence of HCG on the TBC index in biological models]. PMID- 4137409 TI - [Fluorescent microscopic observation of urine exfoliative cells in urinary tract tumor]. PMID- 4137410 TI - [Gastroduodenal ulcer: pathogenetic and clinical aspects]. PMID- 4137411 TI - [Histamine receptors]. PMID- 4137412 TI - [Histoenzymatic characteristics of the connective tissue and vessels of the palatine tonsils in chronic tonsillitis from the age viewpoint]. PMID- 4137413 TI - [Histological and ultrastructural study of livers of rats maintained chronically hypercapnic (author's transl)]. PMID- 4137414 TI - [Hormonal activity of the thyroid gland in patients with stomach cancer]. PMID- 4137415 TI - [Hyperthyroidosis factitia]. PMID- 4137416 TI - [Hypothesis concerning the evolution of the HL-A system]. PMID- 4137417 TI - [HL-A antigens and beta-2-microglobulin in urine]. PMID- 4137418 TI - [HL-A antigens in children with congenital malformations (author's transl)]. PMID- 4137419 TI - [HL-A system. Genetic aspects and polymorphism (author's transl)]. PMID- 4137420 TI - [Immunologic studies in oligophrenics (author's transl)]. PMID- 4137421 TI - [Immunological activity of dihydrostreptomycin sulfate--precipitated fractions from cell-free intestinal bacterial lysates]. PMID- 4137422 TI - [Immunological aspects in gamma globulin therapy of allergic diseases]. PMID- 4137424 TI - [Immunomorphological study of surviving and fixed tissue blocks using contact microscopy]. PMID- 4137423 TI - [Immunological processes and their morphological manifestations in the development of tumors]. PMID- 4137425 TI - [Influence of glucose blood level on the human plasma inhibitor-alpha 2 (author's transl)]. PMID- 4137426 TI - [Influence of hormone-induced over-gestation on the morphology of the rabbit placenta]. PMID- 4137427 TI - [Inhibition of the anticomplement activity of gamma globulin through the addition of transferrin]. PMID- 4137428 TI - [Insecticides, antibiotics and other environmental chemicals as contaminants in infant nutrition (author's transl)]. PMID- 4137429 TI - [Intra-myocardial contrast injection (author's transl)]. PMID- 4137430 TI - [Is a urological specialist economically justified in county hospitals?]. PMID- 4137431 TI - [Isolation and translation of mRNAs for specific proteins (author's transl)]. PMID- 4137432 TI - [Level of protein-bound iodine in the blood serum in simple glaucoma]. PMID- 4137433 TI - [Liquor electrophoresis in connatal encephalitis]. PMID- 4137434 TI - [Localization of somatic antigen in Vibrio, established by using an immunoferritin method]. PMID- 4137435 TI - [Long-term experiences with synchronized cardiostimulation. II. Problems of inhibition of cardiostimulators on demand of Czechoslovak production]. PMID- 4137436 TI - [Method of obtaining and the characteristics of an antiserum that neutralizes Escherichia coli and Vibrio cholera enterotoxins]. PMID- 4137437 TI - [Modern laboratory methods for the evaluation of the thyroid function. II. Non isotope methods]. PMID- 4137438 TI - [Morphological study of certain nucleoprotein structures in the nuclei of lymphocytes cultivated in vitro in the presence of phytohemagglutinins]. PMID- 4137439 TI - [Mucopolysaccharides in their significance for vascular pathology with particular reference to the aging process and arteriosclerosis]. PMID- 4137440 TI - [Multiple meningiomata. Hereditary disease or metastasis? (author's transl)]. PMID- 4137441 TI - [New aspects of thyroid gland diagnostics]. PMID- 4137442 TI - [Orchidectomy and oestrogen therapy of carcinoma of the prostate (author's transl)]. PMID- 4137443 TI - [Orientation of scar tissue after incision of the optic nerve (author's transl)]. PMID- 4137444 TI - [Palliative surgery in gastrointestinal neoplasms]. PMID- 4137445 TI - [Pathomorphological principles and types of glomerulonephritis (author's transl)]. PMID- 4137446 TI - [Pathomorphology and pathomorphosis of tuberculosis of the peripheral lymph nodes]. PMID- 4137447 TI - [Peripheria neurovegetative portionis vaginalis uteri mulieris. V. Study on peripheral vegetable nerve fibres in squamous cell carcinoma of the portio vaginalis uteri and its preliminary stage by means of supravital methylene staining]. PMID- 4137448 TI - [Permanent continuing dental education]. PMID- 4137449 TI - [Phytohemagglutinin-induced increase of euchromatin contents in human lymphocytes]. PMID- 4137450 TI - [Plasma TSH during treatment with thyreostatic agents]. PMID- 4137451 TI - [Preliminary results of the use of human anti-measles immunoglobulin in measles encephalitis]. PMID- 4137452 TI - [Presence of RNase H activity not associated with reverse transcriptase activity in Moloney murine sarcoma virions]. PMID- 4137453 TI - [Present status of prenatal sex-diagnosis (author's transl)]. PMID- 4137454 TI - [Preventive treatment of thromboembolic postoperative complications in urology using subcutaneous calcium heparinate]. PMID- 4137455 TI - [Principles in the treatment of malignant pulmonary tumors with cyostatics]. PMID- 4137456 TI - [Problems in the diagnosis of mild early infantile brain damage in children]. PMID- 4137457 TI - [Prognosis for patients with inoperable bronchial carcinoma]. PMID- 4137458 TI - [Prostatic hypertrophy associated with bladder polyps. Report of 18 cases (author's transl)]. PMID- 4137459 TI - [Protein staining following acrylamide gel electrophoresis]. PMID- 4137460 TI - [Quantitative determination of liver steatosis (author's transl)]. PMID- 4137461 TI - [Radiotherapy in the management of breast carcinoma (author's transl)]. PMID- 4137462 TI - [Resin linked analogue of actinomycin C1 (D) and affinity chromatography of nucleic acids (author's transl)]. PMID- 4137463 TI - [Serodiagnosis of toxoplasmosis by means of indirect fluorescent antibody technic]. PMID- 4137464 TI - [Some data on the identification of the precipitation curves obtained by the immunoelectrophoresis method]. PMID- 4137465 TI - [Staphylococcal infection in a surgical clinic]. PMID- 4137466 TI - [Structure and affinity of antibodies in turtles]. PMID- 4137467 TI - [Study of the viability of corneal endothelium preserved in a moist chamber]. PMID- 4137468 TI - [Subcapital upper-arm fracture]. PMID- 4137469 TI - [Symptoms and treatment of bulbar stenosis of the ureter in adults (author's transl)]. PMID- 4137470 TI - [Systemic lupus erythematosus and lupoid diseases. Finding of typical LE cells in 2,000 patients with various internal and rheumatic diseases]. PMID- 4137471 TI - [Temperature dependent mutants of oncorna viruses (author's transl)]. PMID- 4137472 TI - [The articular manifestations of Whipple's disease. Apropos of a case, with histological study of the synovial membrane]. PMID- 4137473 TI - [The diagnose and the differential diagnose of the monarthritis (author's transl)]. PMID- 4137474 TI - [The effects of the exhaust from cars on man and on environment (author's transl)]. PMID- 4137475 TI - [The handicapped child. Etiology, diagnosis and care (author's transl)]. PMID- 4137476 TI - [The magnetic properties of enzymes and amino acids]. PMID- 4137477 TI - [The scar mesenchyma after experimental contusion of the optic nerve (author's transl)]. PMID- 4137478 TI - [The significance of ventricular extrasystoles]. PMID- 4137479 TI - [The tuberculosis problem in Botswana]. PMID- 4137480 TI - [Therapy of chronic hepatitis]. PMID- 4137481 TI - [Treatment of immunodeficiency]. PMID- 4137482 TI - [Treatment of inoperable carcinoma patients in old age]. PMID- 4137483 TI - [Treatment of occupational allergic dermatitis and eczema with histaglobin]. PMID- 4137484 TI - [Tumorous prostatic diseases. I. Prostatic adenoma--genesis, clinical aspects, therapy]. PMID- 4137485 TI - [Tyrothricin biosynthesis (author's transl)]. PMID- 4137486 TI - [Ultrastructure of the proximal tubule in rat kidney after pretreatment with a pentosane sulfuric acid ester (author's transl)]. PMID- 4137487 TI - [Use and results of treatment with phenytoin infusion concentrate (author's transl)]. PMID- 4137488 TI - [Use of cytostatic preparations in certain severe dermatoses (psoriasis, pemphigus, hemodermia)]. PMID- 4137489 TI - [Use of luminescence microscopy in the evaluation of the placenta in cases of hypotrophic newborn infants]. PMID- 4137490 TI - [UV-spectrophotometry in drug control. 12. Characterization and estimation of drugs with naphthalene-chromophores]. PMID- 4137491 TI - [Whipple's disease. Apropos of an autopsy]. PMID- 4137492 TI - [2 cases of granulomatous prostatitis. Anatomo-clinical comments]. PMID- 4137493 TI - [3 cases of "acquired B" erythrocyte phenotype. The pseudo-B specificity appears to be acquired at the expense of the A specificity]. PMID- 4137494 TI - [3 cases of osteoradionecrosis of the mandible treated with antibiotics with or without gammaglobulins]. PMID- 4137495 TI - A case of congenital toxoplasmosis with active chorioretinitis. Parasitological and histopathological findings. PMID- 4137496 TI - A case of sex-linked hereditary dysgammaglobulinaemia accompanied by interstitial pneumonia and lasting neutropenia. PMID- 4137497 TI - A cellular basis for auto-immunity. PMID- 4137498 TI - A clinical and histopathological study of twenty-seven cases of Urbach-wiethe disease. Dermatologic, gastroenterologic, neurophysiologic, ophthalmologic and roentgendiagnostic aspects, as well as the results of some clinico-chemical and histochemical examinations. PMID- 4137499 TI - A comparative immunochemical study of Shigella sonnei haptene polysaccharides. PMID- 4137500 TI - A double blind trial of a polyene macrolide--nystatin--in the treatment of benign prostatic hyperplasia in man. PMID- 4137501 TI - A histological evaluation of peripheral nerve repairs. PMID- 4137502 TI - A histopathological report on the nature of the epithelium and underlying connective tissue which surrounds oral implants. PMID- 4137503 TI - A light and electron microscopic study of the adenomatoid odontogenic tumor. PMID- 4137504 TI - A method for the mathematical study of the stained mass of the chromosomes. PMID- 4137505 TI - A micro procedure for fast typing of the genetic variants of phosphoglucomutase. PMID- 4137506 TI - A microculture technique utilizing whole blood for mouse chromosome analysis. PMID- 4137508 TI - A new method for identification of individual nephrons for light and electronmicroscopy. PMID- 4137507 TI - A new group of oncornaviruses. PMID- 4137509 TI - A new polysaccharide antigen common to Staphylococcus aureus strains of bacteriophage type 187. PMID- 4137510 TI - A new, simple method for the preparation of lymphocytes bearing specific receptors. PMID- 4137511 TI - A perspective on antitrypsin deficiency. PMID- 4137512 TI - A public speaking course for foreign medical graduates. PMID- 4137513 TI - A rabbit with the allotypic phenotype: ala2a3 b4b5b6. PMID- 4137514 TI - A simple and reproducible method of isolating rat peritoneal mast cells in high yield and purity. PMID- 4137515 TI - A simple method for the preparation of pure and active gamma-globulin-ferritin conjugates using glutaraldehyde. PMID- 4137516 TI - A study of questions connected with the production of immunoglobulin preparations labelled with fluorescein isothiocyanate. PMID- 4137517 TI - A supravital stain for nucleoli in human lymphocytes. PMID- 4137519 TI - A unified theory of the control of actin and myosin in nonmuscle movements. PMID- 4137518 TI - A theory of lymphocyte blast transformation (LBT) and malignant change based on proteolytic cleavage of trigger peptide: the detendomer. PMID- 4137520 TI - Abnormality in normal development. A concept of symptom formation in childhood. PMID- 4137521 TI - Acid-base diagrams maths, myths, and measurements. PMID- 4137522 TI - Actinomycin binding and uridine incorporation by human normal bone marrow cells. PMID- 4137523 TI - Active-passive immunization of human subjects against tetanus using homologous gamma globulin. PMID- 4137524 TI - Acute effects of gonadotrophins and prostaglandins on the metabolism of isolated ovarian follicles from PMSG-treated immature rats. PMID- 4137525 TI - Adenoid cystic carcinoma of the prostate. Report of a case. PMID- 4137526 TI - Age and organ dependent variations in the number of thymus derived RTLA bearing cells. PMID- 4137528 TI - Alizarin red. Vital staining of cornea and conjunctiva. PMID- 4137527 TI - Air pollution and the eye. PMID- 4137529 TI - Alpha chain determinants on the membrane of immunoglobulin synthesizing cells. PMID- 4137530 TI - Alpha Fetoprotein: An index of progression or regression of hepatoma, and a target for immunotherapy. AB - CLINICAL AND LABORATORY STUDIES OF AFP PRODUCING HEPATOMAS DEMONSTRATED THAT: 1) serum AFP levels correlated directly with tumor growth; 2) circulating AFP could be cleared by passive administration of an. excess of anti-AFP; and 3) highly specific anti-AFP functioned as a carrier to localize diagnostic and possibly therapeutic amounts of radioactivity in hepatoma tissue. These studies helped elucidate certain criteria which should be fulfilled before attempts to initiate passive humoral immunotherapy of cancer are undertaken. PMID- 4137531 TI - Ampicillin nephropathy. PMID- 4137532 TI - An attempt to correlate RNA-templated DNA polymerase activity with virus-like particles in human milk: murine mammary tumor virus (MuMTV) as a model system. PMID- 4137533 TI - An audio-visual teaching programme for training home dialysis patients. PMID- 4137534 TI - An electron microscopic study of the tympanojugular glomus. PMID- 4137535 TI - An epidemic of canine scabies in man. PMID- 4137536 TI - An immunological study of subacute sclerosing panencephalitis: measles and tissue antigens and immunoglobulins. PMID- 4137537 TI - An informatic analysis of serum protein disturbances in clinical pathology. PMID- 4137538 TI - An introduction to dentistry for the blind. PMID- 4137539 TI - Andrew Wilson. PMID- 4137540 TI - Antegrade concealed conduction to the His bundle; documentation with His bundle recording. PMID- 4137541 TI - Anti-immunoglobulin antibodies in immunodeficiencies: their influence on intolerance reactions to gamma-globulin administration. PMID- 4137542 TI - Antibody affinity. VII. Multivalent interaction of anti-lactoside antibody. PMID- 4137543 TI - Antidepressant action of tryptophan. PMID- 4137544 TI - Antigenic properties of a non-collagenous reticulin component of normal connective tissue. PMID- 4137545 TI - Antitumor antibiotics. PMID- 4137546 TI - Apparent violation of "Landsteiner's law". PMID- 4137548 TI - Association constant and heterogeneity index of antibodies specific for a natural determinant of a bacterial protein. Time-course studies during the in vitro immune response to a distinct site of Escherichia coli beta-D-galactosidase. PMID- 4137549 TI - Association of S-IgA subunits. PMID- 4137550 TI - Atherosclerosis in aortocoronary vein grafts. PMID- 4137547 TI - Are gastrin-cells present in mammalian pancreatic islets? PMID- 4137551 TI - Atypical azurophilic crystals in chronic lymphocytic leukemia. A case report and comparison with other crystalline inclusions. PMID- 4137552 TI - Australia antigen (HB-Ag) subtyping by a sensitive tanned cell haemagglutination inhibition technique. PMID- 4137553 TI - Autoradiographic studies of migrating neurons and astrocytes of human fetal cerebral cortex in vitro. PMID- 4137554 TI - Balloon atrioseptostomy. A palliative measure for transposition of the great arteries and certain other critical congenital cardiac defects. PMID- 4137555 TI - Binding of antinucleoside antibody to DNA. PMID- 4137556 TI - Binding of secretory piece to polymeric IgA and IgM paraproteins in vitro. PMID- 4137557 TI - Biochemical properties of reverse transcriptase activities from human cells and RNA tumor viruses. PMID- 4137558 TI - Biondi-like cell inclusions in the human iris. PMID- 4137559 TI - Biosynthesis and metabolism of collagen and its role in tissue repair processes. PMID- 4137560 TI - Biosynthesis of hypothalamic hypophysiotropic factors. PMID- 4137561 TI - Blood group investigations among the gypsy population of Hungary. II. Examinations of haptoglobin types and level and GM(1) factor. PMID- 4137562 TI - Blood group specificity of the lectin from Lotus tetragonolobus. PMID- 4137563 TI - Bulk flow of interstitial fluid after intracranial injection of blue dextran 2000. PMID- 4137564 TI - Carcinoma of the pancreas. A program for increasing survival. PMID- 4137565 TI - Cell mediated lympholysis in man. Occurrence of unexpected, HL-A (LA and FOUR) irrelevant lympholysis. PMID- 4137566 TI - Cell types contributing to the biosynthesis of sIgA. PMID- 4137567 TI - Cells involved in the immune response. XXVI. The demonstration of bone marrow specific antigens in the rabbit. PMID- 4137568 TI - Cells involved in the immune response. XXVII. The demonstration of appendix specific antigens in the rabbit. PMID- 4137569 TI - Cellular immunity in systemic lupus erythematosus. PMID- 4137570 TI - Centric fusion, satellite DNA, and DNA polarity in mouse chromosomes. AB - A fluorescent staining technique has demonstrated a contralateral arrangement of fluorescent spots in the centromeric region of mouse metacentric chromosomes which have resulted from centric fusion. The results suggest that centric fusion involves the maintenance of DNA polaritv through the centromere and that the thymidine-rich chain of satellite DNA in the centromeric region is associated with the same DNA chain in every mouse autosome. PMID- 4137571 TI - Changes of the luminal surface of the rat uterus at blastocyst implantation. Scanning electron microscopy and ruthenium red staining. PMID- 4137572 TI - Characteristics of SC-Ig complexes formed in vitro. PMID- 4137573 TI - Characterization of the surface protein components in adipocyte plasma membranes. PMID- 4137574 TI - Chemoimmunotherapy of cancer. 1. PMID- 4137575 TI - Christchurch Clinical School audio visual services for lecture theatres and other teaching areas. PMID- 4137576 TI - Chromosomes of the African ground squirrel, Xerus rutilus (Rodentia: Sciuridae). PMID- 4137577 TI - Chronic experimental allergic encephalomyelitis in inbred guinea pigs. An ultrastructural study. PMID- 4137578 TI - Circadian rhythm of cell proliferation in rat liver: synchronization by feeding habits. PMID- 4137579 TI - Circulating anticoagulant in disseminated lupus erythematosus. Proposed mode of action. PMID- 4137580 TI - Clonal depletion in neonatal tolerance. AB - Specific unresponsiveness can be induced in neonatal and adult BALB/c mice by antibody against antigen-specific receptor (antireceptor antibody). When heterologous antireceptor antibody is used in the indirect fluorescence technique, the number of fluorescent cells in these animals is significantly lower than in normal animals. Fluorescent cells appear after a relatively brief incubation of cells from adult-suppressed animals, whereas no fluorescent cells are detected when cells from neonatally treated animals are incubated briefly. Evidently, treating neonatal mice with antireceptor antibody specifically depletes the antigen-responsive clone. In contrast, antireceptor antibody causes reversible blockade of responsive cells in adult-suppressed animals. PMID- 4137581 TI - Clonal nature of the immune response to phosphorylcholine. IV. Idiotypic uniformity of binding site-associated antigenic determinants among mouse antiphosphorylcholine antibodies. AB - A new idiotypic determinant(s) on mouse anti-PC antibodies is described. Antibodies to the determinant(s) were raised in rabbits by immunization with HOPC 8, a PC-binding myeloma protein, and were isolated from HOPC 8 immunoadsorbent by elution with PC. These antibodies react with binding site determinants on anti-PC antibodies raised in all 15 inbred mouse strains tested regardless of histocompatibility or allotype, but fail to react with antibodies of other specificities or with anti-PC antibodies raised in other rodent species. These results correlate closely with other studies which show similar binding specificity of anti-PC antibodies raised in 17 different strains of mice. The site-associated idiotypic determinant(s) is clearly distinct from that detected by mouse anti-HOPC 8 antisera. This latter determinant(s) is present on anti-PC antibodies of only a few strains of mice and may not be in the binding site. PMID- 4137582 TI - Common antigenic structures of HL-A antigens. 3. An HL-A common antigenic marker closely associated with HL-A alloantigenic activity and detected by use of rabbit anti-rhesus monkey cell membrane antibodies. PMID- 4137583 TI - Common misconceptions about the prostate gland. PMID- 4137584 TI - Community agency includes role-PLAYING, DEMONSTRATIONS IN CAREER-DAY PROGRAMS. PMID- 4137585 TI - Comparative biochemical properties of RNA-directed DNA polymerases from Rauscher murine leukemia virus and avian myeloblastosis virus. PMID- 4137586 TI - Comparative chromosome studies in Cetacea. PMID- 4137587 TI - Comparison of ventricular parasystole with other dysrhythmias after acute myocardial infarction. PMID- 4137588 TI - Comparisons of glaucomatous visual fields using the black tangent screen and the Goldmann perimeter. PMID- 4137589 TI - Complex formation of guinea-pig liver diamine oxidase (histaminase) with heparinoids. PMID- 4137591 TI - Control of respirator-associated infection due to Pseudomonas aeruginosa. PMID- 4137592 TI - Control of spillover. The importance of Kupffer-cell function in clinical medicine. PMID- 4137590 TI - Contrast media as histamine liberators in man. PMID- 4137593 TI - Controlled trial of co-trimoxazole in children with urinary-tract infection. Bacteriological efficacy and haematological toxicity. PMID- 4137594 TI - Corneal collagenase: specific cleavage of types (alpha 1)2 alpha 2 and (alpha 1)3 collagens. PMID- 4137595 TI - Correction of neutropenia associated with dysgammaglobulinemia. PMID- 4137596 TI - Correlation between the synthetic activity and classification of reticulocytes. PMID- 4137597 TI - Coumarin anticoagulants: a review of some current research areas. PMID- 4137598 TI - Cytology of leukocyte concentrates. PMID- 4137599 TI - Cytotoxicity of three endodontic intracanal medicaments. PMID- 4137600 TI - Decreased globin messenger RNA in thalassemia by hydridization and biologic activity assays. PMID- 4137601 TI - Defect in neutrophil granulocyte chemotaxis in Job's syndrome of recurrent "cold" staphylococcal abscesses. PMID- 4137602 TI - Degeneration argyrophilia as an index of neural maturation: studies on the optic tract of the golden hamster. PMID- 4137603 TI - Delayed recovery of intellectual function after minor head injury. PMID- 4137604 TI - Delta5-3beta-hydroxysteroid dehydrogenase and estradiol-17beta-hydroxysteroid dehydrogenase activity in preimplantation hamster embryos. PMID- 4137605 TI - Desensitization in the process of histamine secretion induced by antigen and dextran. AB - 1. Antigen challenge of sensitized rat peritoneal mast cells in the absence of calcium failed to release histamine. The release when calcium was added subsequently declined rapidly, this desensitization being almost complete in 4 min.2. Phosphatidyl serine (10 mug/ml.) reduced the rate of desensitization so that decay of the response to added calcium was not complete after 16 min.3. Exposing normal cells to dextran resulted in a slow rate of desensitization, the response to phosphatidyl serine added with calcium having decayed by only 27% within 10 min.4. Phosphatidyl serine added with dextran prevented desensitization so that the response to subsequently added calcium did not decay even after an interval of 20 min.5. Cells activated by dextran and calcium became rapidly desensitized as shown by decay of the response to added phosphatidyl serine which was almost complete by 5 min.6. Histamine release by the calcium ionophore (A 23187) added to cells at intervals before the addition of calcium did not show significant decay.7. Desensitization of the cells to antigen did not change their response to the ionophore. PMID- 4137606 TI - Desensitization of rat mast cells by the use of theophyllin. PMID- 4137607 TI - Detection of type C viruses in normal and transformed cells. PMID- 4137608 TI - Determination of the noraml values of some human plasma proteins by means of quantitative radial immunodiffusion. PMID- 4137609 TI - Diagnosis of regional lymph node metastases in cancer of the breast. A study of the lymphatic system of the diseased breast. PMID- 4137611 TI - Differential staining of human and mouse chromosomes in interspecific cell hybrids. PMID- 4137610 TI - Diagnostic value of the PAS-positive lymphocyte index in diabetes. PMID- 4137612 TI - Distribution of heterochromatin in type-3 Y and other chromosomes of Drosophila athabasca. PMID- 4137613 TI - Diversity of antibodies to cross-reacting nitrophenyl haptens in inbred mice. PMID- 4137614 TI - Drug spotlight program: systemic corticosteroid therapy: pharmacology and endocrinologic considerations. PMID- 4137615 TI - DNA polymerase activity from two temperature-sensitive mutants of Rous sarcoma virus is thermolabile. PMID- 4137616 TI - Early psychosomatic symptom and the tendency towards integration. PMID- 4137617 TI - Editorial: "A-huffin' and a-puffin', a-sniffin' and a-suckin.'". PMID- 4137618 TI - Editorial: Accreditation of psychiatric facilities serving children and adolescents. PMID- 4137619 TI - Editorial: Asynergy and ventricular premature beats. PMID- 4137620 TI - Editorial: Computers or nurses? PMID- 4137621 TI - Editorial: Delaying premature labour. PMID- 4137622 TI - Editorial: Does this chemical cause cancer in man? PMID- 4137623 TI - Editorial: Endemic goitre on Idjwi island. PMID- 4137624 TI - Editorial: Immunology and developing countries. PMID- 4137625 TI - Editorial: Neuralgic amyotrophy. PMID- 4137626 TI - Editorial: Occupational leucoderma. PMID- 4137627 TI - Editorial: Oestradiol receptors in human breast cancer. PMID- 4137628 TI - Editorial: Rodent control and lassa fever. PMID- 4137629 TI - Editorial: Something rotten in Scotland, and elsewhere. PMID- 4137630 TI - Editorial: Testing renal function. PMID- 4137631 TI - Editorial: Where the axe is falling. PMID- 4137632 TI - Education of medical students in general pathology. Comparison of learning strategies: lecture, audiovisomat, self instruction. PMID- 4137633 TI - Effect of ethanol on the hypertonic saline-induced histological changes in the hypothalamic neurosecretory system of the spotted owlet, Athene brama Temminck. PMID- 4137634 TI - Effect of histamine releasing agents on the metabolism of exogenous glucose in rat mast cells. PMID- 4137635 TI - Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve. PMID- 4137636 TI - Effect of ribonuclease treatment on nuclear, dRNA-containing 30 S ribonucleoprotein particles. PMID- 4137637 TI - Effects of carbon monoxide on coronary heart disease. PMID- 4137638 TI - Effects of chlordiazepoxide in respiratory failure due to chronic bronchitis. PMID- 4137639 TI - Effects of sodium fluoride and other metabolic inhibitors on basal and TSH stimulated cyclic AMP and thyroid metabolism. PMID- 4137640 TI - Effects of splenectomy on amphibian antibody responses. PMID- 4137641 TI - Effects of stay at high altitude on the serum proteins of man. PMID- 4137642 TI - Elastic tissues in adenoid cyctic carcinomas. PMID- 4137643 TI - Electrical measurement of intestinal absorption of glucose in man. PMID- 4137644 TI - Electron microscope study of Erythema nodosum leprosum. PMID- 4137645 TI - Elevated plasma histamine concentrations in surgery: causes and clinical significance. PMID- 4137646 TI - Elevations in serum glycoprotein-N-acetylneuraminic acid transferases in rats bearing mammary tumors. PMID- 4137647 TI - Endogenous RNA-directed DNA polymerase activity in normal cells. PMID- 4137648 TI - Enzyme histochemical investigations of heterotopic gastric epithelium in the duodenum. PMID- 4137649 TI - Erythropoietin-stimulated proliferation of human red cell precursors in vitro. PMID- 4137650 TI - Ethical dilemmas in the care of the critically ill. PMID- 4137651 TI - Evaluation of the nitroblue tetrazolium test as applied to polymorphonuclear leukocytes in the cerebrospinal fluid. PMID- 4137652 TI - Evidence for a common synthetic origin for secretory and serum IgA. PMID- 4137653 TI - Evidence for identity or close association of the Fc receptor of B lymphocytes and alloantigens determined by the Ir region of the H-2 complex. AB - Immunoglobulin complexes, composed of heat-aggregated human Ig, were shown to bind to mouse B lymphocytes of a variety of strains, but not to either thymocytes or thymus-derived (T) lymphocytes under a variety of conditions. It was shown that this binding was not due to either natural human antibodies against mouse nor to nonspecific binding of human Ig by mouse lymphocytes. Such complexes were shown to bind to the same sites which bind mouse antibody-antigen complexes. This site is known as the Fc receptor. The binding of Ig complexes to mouse B lymphocytes was markedly inhibited by pretreatment of the lymphocytes with anti-H 2 antisera. A series of experiments indicated the specificity of this result, including the fact that this inhibition was shown not to be due to the artifact of shedding of H-2 antibody-antigen complexes, nor to nonspecific steric inhibition. The antibodies within anti-H-2 antisera which were responsible for this inhibition were specific for alloantigens associated with the Ir region of the H-2 complex (Ia antigens). Antiserum specific for these Ia antigens produced inhibition, whereas antisera specific for antigens determined by the K or D regions of the H-2 complex did not. Evidence was obtained using F(1) hybrid cells that at least some Ia antigens of both parental types are expressed on every B lymphocyte (i.e. codominant expression). These data indicate that the Fc receptor and a series of alloantigens controlled by the Ir region of the H-2 complex are identical or closely associated on the B-lymphocyte surface membrane. This observation may have implications for the mechanism of control of the immune response. PMID- 4137654 TI - Evidence for two linked loci controlling ther serologically defined leukocyte antigens of chimpanzees (ChL-A). PMID- 4137655 TI - Evidence of particle-associated RNA-directed DNA polymerase and high molecular weight RNA in human gastrointestinal and lung malignancies. AB - Previous communications have demonstrated that neoplastic cells of human breast cancers, leukemias, lymphomas, sarcomas, and brain tumors contain particles with similar diagnostic attributes as those found in RNA oncornaviruses. The present paper concerns malignancies of the gastrointestinal and pulmonary systems for which, like brain tumors, no suitable animal model or corresponding virus exists. By means of the simultaneous detection assay, these tumors have been found to contain 70S RNA and RNA-directed DNA polymerase encapsulated in particulate components possessing densities of 1.16-1.17 g/ml. Twelve out of 17 (70%) colon carcinomas, three out of five (60%) gastric carcinomas, all of three rectal carcinomas, and seven out of ten (70%) lung carcinomas contained detectable levels of these virus-like entities. None of the corresponding normal tissues was positive. PMID- 4137656 TI - Evidence that different antibodies are involved in the production of immunologically induced teratogenesis and nephritis. PMID- 4137657 TI - Experimental chemotherapy in carcinoma of the cervix. PMID- 4137658 TI - Experimental' pregnancy: the ethical complexities of experimentation with oral contraceptives. PMID- 4137659 TI - Factors limiting the histochemical reaction of choline dehydrogenase activity. PMID- 4137660 TI - Failure of bleomycin to affect humoral or cell-mediated immunity in the mouse. PMID- 4137661 TI - Familial clustering of hepatitis B antigen: a study in relatives of patients with liver diseases and hepatitis B antigenaemia. AB - Twelve of the 100 family contacts of 29 patients with transient and persistent hepatitis B antigenaemia were found to be positive for hepatitis B antigen (HBAg). No relation was found between familial clustering and the nature of liver disease or the duration of antigenaemia in the index cases.Eight affected relatives were apparently healthy carriers of HBAG, one had cirrhosis, and three (in the same family) developed acute viral hepatitis.The absence of parenteral exposure in the HBA,-positive family contacts and the identity in antigenic determinants d or y with those of the index cases, suggest a non-parenteral spread of HBAg in families of patients with HBAg-associated liver diseases. PMID- 4137662 TI - Familial Hodgkin's disease: an environmental and genetic disorder. PMID- 4137663 TI - Fiber types in human masticatory muscles. Relation to function. PMID- 4137664 TI - Fibre composition, enzyme activity and concentrations of metabolites and electrolytes in muscles of standardbred horses. PMID- 4137665 TI - Fibrinoid necrosis in granuloma induced by imcomplete Freund adjuvant. PMID- 4137666 TI - Fibrinolytic split products (FSP) and ethanol gelation test in preoperative evaluation of patients with prostatic disease. PMID- 4137667 TI - Fine structural, HaLV gs antigen, and reverse transcriptase study of the Syrian hamster stilbestrol-induced renal carcinoma. PMID- 4137668 TI - Fine structure of the synaptic endings on the Mauthner cell of the goldfish. PMID- 4137670 TI - Five-year ballistocardiographic follow-up of a patient with an implanted starr valve in mitral position. PMID- 4137669 TI - Fingerprinting techniques as aids in the analysis of composite chemical pollutants in the environment. PMID- 4137671 TI - Fluorescent staining for Mycobacterium leprae in tissue sections. Comparison with Fite-Faraco procedure. PMID- 4137672 TI - Focal aortic injury caused by cannulation: increased plasma protein accumulation and thrombosis. PMID- 4137673 TI - Follow-up of patients with pulmonary tuberculosis adequately treated by chemotherapy: is this really necessary? PMID- 4137674 TI - Formaldehyde condensation at reduced temperature. Increased sensitivity and specificity of the fluorescence microscopic method for demonstrating primary catecholamines. PMID- 4137675 TI - Functional characterization of membrane components of cytotoxic peritoneal exudate T lymphocytes. I. Search for T cell receptor activity in lymphocyte membrane fractions. PMID- 4137676 TI - Furcation canals in the human mandibular first molar. PMID- 4137677 TI - Further observations on a human syncytial virus from a nasopharyngeal carcinoma. PMID- 4137678 TI - G-G translocation and chronic myelocytic leukaemia. PMID- 4137679 TI - Galvanic separation of X- and Y-bearing human spermatozoa. PMID- 4137680 TI - Gamma-heavy chain disease. Preliminary studies in three cases. PMID- 4137681 TI - Gastric endocrine cell proliferation. Association with Zollinger-Ellison syndrome. PMID- 4137683 TI - Genetically-associated variations in the distribution of dentate granule cell synapses upon the pyramidal cell dendrites in mouse hippocampus. PMID- 4137682 TI - Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L tyrosine 10 (GAT). AB - In recent studies we have found that GAT not only fails to elicit a GAT-specific response in nonresponder mice but also specifically decreases the ability of nonresponder mice to develop a GAT-specific PFC response to a subsequent challenge with GAT bound to the immunogenic carrier, MBSA. Studies presented in this paper demonstrate that B cells from nonresponder, DBA/1 mice rendered unresponsive by GAT in vivo can respond in vitro to GAT-MBSA if exogenous, carrier-primed T cells are added to the cultures. The unresponsiveness was shown to be the result of impaired carrier-specific helper T-cell function in the spleen cells of GAT-primed mice. Spleen cells from GAT-primed mice specifically suppressed the GAT-specific PFC response of spleen cells from normal DBA/1 mice incubated with GAT-MBSA. This suppression was prevented by pretreatment of GAT primed spleen cells with anti-theta serum plus C or X irradiation. Identification of the suppressor cells as T cells was confirmed by the demonstration that suppressor cells were confined to the fraction of the column-purified lymphocytes which contained theta-positive cells and a few non-Ig-bearing cells. The significance of these data to our understanding of Ir-gene regulation of the immune response is discussed. PMID- 4137684 TI - Genetics and evolution of human immunoglobulin A. PMID- 4137685 TI - Glucagon-mediated changes in the concentration of rat hepatic tyrosine transaminase: an immunochemical analysis. PMID- 4137686 TI - Glucocorticoid inhibition of antigen-evoked histamine release from human skin. PMID- 4137687 TI - Glutaraldehyde fixed-antigen sensitized stable cells in indirect hemagglutination test for rapid diagnosis of hydatid disease, trichinosis and amoebiasis. PMID- 4137688 TI - Graves disease and idiopathic thrombocytopenic purpura. PMID- 4137689 TI - Gut-associated lymphoblasts and intestinal IgA plasma cells. PMID- 4137690 TI - Handwashing: surgical wards. Soap and water compared with 70% alcohol. PMID- 4137691 TI - Hapten-carrier relationships in immunological unresponsiveness. II. Decrease of antibody affinity and specificity in B cell tolerance. PMID- 4137692 TI - Hapten-specific IgE antibody responses in mice. IV. Evidence for distinctive sensitivities of IgE and IgG B lymphocytes to the regulatory influence of T cells. PMID- 4137693 TI - Hapten-specific IgE antibody responses in mice. 3. Establishment of parameters for generation of helper T cell function regulating the primary and secondary responses of IgE and IgG B lymphocytes. PMID- 4137694 TI - Hearing loss in paranoid and affective psychoses of the elderly. PMID- 4137695 TI - Hepatitis A and B. PMID- 4137696 TI - Hepatitis B transmitted by a human bite. PMID- 4137697 TI - Herpesvirus hominis: from latency to carcinogenesis? PMID- 4137698 TI - Heterologous recombination between mouse myeloma 315 heavy chains and rabbit antibody light chains: structural and functional properties of the hybrid molecules. PMID- 4137700 TI - High-speed liquid chromatographic cleanup of environmental samples prior to the gas chromatographic determination of lindane. PMID- 4137699 TI - HeLa cell R-deoxyribonucleic acid polymerases. Separation and characterization of two enzymatic activities. PMID- 4137701 TI - Histamine release by dextrans from rat peritoneal cells. PMID- 4137702 TI - Histochemical and electron microscopic studies on argyrophil granules in eccrine sweat gland cells in the pigmented skin of Riehl's melanosis. I. Histochemical studies. PMID- 4137703 TI - Histochemical and electron microscopic studies on argyrophil granules in eccrine sweat gland cells in the pigmented skin of Riehl's melanosis. II. Electronmicroscopic studies. PMID- 4137704 TI - Histochemical enzyme profile of the masseter muscle in different mammalian species. PMID- 4137705 TI - Histological, histochemical and ultrastructural studies on the nature of hyalin bodies in odontogenic cysts. PMID- 4137707 TI - Human leukocyte locus A (HL-A) antigens and infectious mononucleosis. PMID- 4137706 TI - Horseradish peroxidase histochemistry: a new method for tracing efferent projections in the central nervous system. PMID- 4137708 TI - Human secretory component. NH2-terminal amino acid sequences and peptide maps of the form occurring in exocrine immunoglobulin A and the free form. PMID- 4137709 TI - Humoral and cell-mediated immune responses of Lewis rats to syngeneic basic protein of myelin. PMID- 4137710 TI - HL-A antibodies and cold lymphocytotoxins. PMID- 4137711 TI - HL-A antigens and diabetes mellitus. PMID- 4137712 TI - HL-A histocompatibility antigens and skin diseases. PMID- 4137713 TI - HL-A in psoriasis vulgaris and in pustular psoriasis--population and family studies. PMID- 4137714 TI - Identification of human and mouse chromosomes in human-mouse hybrids by centromere fluorescence. PMID- 4137715 TI - Imagery techniques in psychiatry. PMID- 4137716 TI - Immunoenzymology of Clostridium histolyticum collagenase. PMID- 4137717 TI - Immunogenicity of lowly and highly derivatized dinitrophenyl-bovine gamma globulin in different strains of guinea pigs. PMID- 4137718 TI - Immunoglobulins, basic myelin proteins and age in man and monkeys. PMID- 4137719 TI - Immunohistochemistry of liver in alpha1-antitrypsin deficiency. A comparative study. PMID- 4137720 TI - Immunological studies in nephropathies accompanying childhood diabetes mellitus. PMID- 4137721 TI - Improved plasma culture system for production of erythrocytic colonies in vitro: quantitative assay method for CFU-E. PMID- 4137722 TI - In vitro hyposensitization of rat mast cells by antigen. PMID- 4137723 TI - In vivo kinetic studies in human myeloma. PMID- 4137724 TI - Inborn errors of morphogenesis. A review of localized hereditary malformations. PMID- 4137725 TI - Induction of endoreduplication in cultured mammalian cells by some chemical mutagens. PMID- 4137726 TI - Infectious DNA intermediate of an oncogenic RNA virus. PMID- 4137727 TI - Influence of orally administered antibiotics on anti-T agglutinin of normal subjects and of cirrhotic patients. PMID- 4137728 TI - Inhibition by nicotinamide of a homologous PCA reaction and antigen-induced histamine release from isolated rat peritoneal mast cells. PMID- 4137729 TI - Inhibition of the growth of tumour cells in culture by noxytiolin. PMID- 4137730 TI - Initiation of antibody responses by different classes of lymphocytes. IV. Lymphocytes involved in the primary antibody response to a hapten-protein conjugate. PMID- 4137731 TI - Interferon effect on cellular functions: enhancement of virus induced inhibition of host cell protein synthesis in interferon-treated cells. PMID- 4137732 TI - Intracellular localization of basement membrane antigen in parietal yolk sac cells. AB - Basement membrane antigen was localized in murine parietal yolk sac cells using the peroxidase-labeled antibody technic. In these cells the antigen can be localized in the rough endoplasmic reticulum and perinuclear space. In spite of the proven ability of the antibody to permeate all cell compartments, the antigen was never localized within elements of the Golgi complex. These findings suggest that the rough endoplasmic reticulum of the parietal yolk sac cells is responsible for the synthesis of the antigenic portion of the basement membrane molecule. At the present time there is no evidence implicating the Golgi complex in the synthesis or intracellular transport of the antigenic portion of basement membrane. PMID- 4137733 TI - Isoelectric focusing in gels. PMID- 4137734 TI - Isolation and characterization of catalase produced by Mycobacterium tuberculosis. PMID- 4137735 TI - Isolation and localization of an iron-binding rabbit seminal plasma antigen. PMID- 4137736 TI - Isolation of mast cell degranulators from the celomatic fluid of Parascaris equorum. PMID- 4137737 TI - Isolation of microsomal poly(A)-RNA from rat brain directing the synthesis of the myelin encephalitogenic protein in Xenopus oocytes. PMID- 4137738 TI - Isolation of recombinant IgG molecules carrying heavy chain allotypes transmitted in repulsion. PMID- 4137739 TI - Kinetic studies on phosphorylation of 5-azacytidine with the purified uridine cytidine kinase from calf thymus. PMID- 4137740 TI - Kinetocardiographic findings in ventricular premature beats. An atraumatic approach to the problem of cardiac dyssynergy. PMID- 4137741 TI - L-cystinyl-di-beta-naphthylamide hydrolase ("oxytocinase") in human colostrum and early milk plasma. Separation of two isozymes by acrylamide gel electrophoresis. PMID- 4137742 TI - Later responses of alcoholics to crisis. PMID- 4137743 TI - Lateral asymmetry in the fluorescence of human Y chromosomes stained with 33 258 Hoechst. PMID- 4137744 TI - Lectin and agglutinin receptors of red cell components. PMID- 4137745 TI - Letter: Acneiform lesions in combined rifampicin treatment in Africans. PMID- 4137746 TI - Letter: Activity of silver sulphadiazine against dermatophytes. PMID- 4137747 TI - Letter: Aetiology of kwashiorkor. PMID- 4137749 TI - Letter: Anencephalus and legitimacy. PMID- 4137748 TI - Letter: Alpha-fetoprotein in amniotic fluid in early normal pregnancy and intrauterine fetal death. PMID- 4137750 TI - Letter: Antenatal diagnosis of genetic disease. PMID- 4137752 TI - Letter: Assay of gentamicin. PMID- 4137753 TI - Letter: B-lymphocyte nature of hairy cells in hairy-cell leukaemia. PMID- 4137751 TI - Letter: Antibiotic-bone-cement mixtures in prevention of infection following total joint replacement. PMID- 4137754 TI - Letter: Biochemical lesion in vitamin-B12 deficiency in man. PMID- 4137755 TI - Letter: Blood-lead levels, behaviour, and intelligence. PMID- 4137756 TI - Letter: Catalin, quinones, and cataract. PMID- 4137757 TI - Letter: Cervical cancer and sexual behaviour. PMID- 4137758 TI - Letter: Classification of non-Hodgkin's lymphomas. PMID- 4137759 TI - Letter: Cleavage of heme from horseradish peroxidase by methanol with inhibition of enzymic activity. PMID- 4137760 TI - Letter: Complex and polyfunctional antibodies. PMID- 4137761 TI - Letter: Continuous blood-sampling. PMID- 4137762 TI - Letter: Corticosteroids in Landry-Guillain-Barre-Strohl syndrome. PMID- 4137763 TI - Letter: Cyclophosphamide and neoplasia. PMID- 4137764 TI - Letter: Diagnosis and treatment of hypertension. PMID- 4137765 TI - Letter: Diagnosis and treatment of hypertension. PMID- 4137766 TI - Letter: Differentiation between neonatal hepatitis and biliary atresia by measuring serum-alpha-fetoprotein. PMID- 4137767 TI - Letter: Drug induced aplastic anaemia. PMID- 4137768 TI - Letter: Endoscopy in acute gastrointestinal haemorrhage. PMID- 4137769 TI - Letter: Epilepsy in children. PMID- 4137770 TI - Letter: Evaluation of laboratory tests. PMID- 4137771 TI - Letter: Fasting blood-glucose levels. PMID- 4137772 TI - Letter: Fever in thalassaemia. PMID- 4137774 TI - Letter: Free fatty acids and acute myocardial infarction. PMID- 4137773 TI - Letter: Follow-up study of serum-creatine-kinase in carriers of Duchenne muscular dystrophy. PMID- 4137775 TI - Letter: Haemophilia carriers. PMID- 4137776 TI - Letter: Hazards of vinyl chloride. PMID- 4137777 TI - Letter: Head injury and defibrination. PMID- 4137778 TI - Letter: Health services in Chile. PMID- 4137779 TI - Letter: Heparin thrombin clotting-time and platelet factor 4. PMID- 4137780 TI - Letter: Heparin-induced lipolysis in the elderly. PMID- 4137781 TI - Letter: Heterologous stimulation of hepatitis-B antigen. PMID- 4137782 TI - Letter: Hyposplenism in ulcerative colitis. PMID- 4137783 TI - Letter: Iron poisoning: another energy crisis. PMID- 4137784 TI - Letter: Large intestinal-biopsy capsules and small babies. PMID- 4137785 TI - Letter: Leigh's disease and failure of automatic respiration. PMID- 4137786 TI - Letter: Lymphocyte transformation and oral contraceptives. PMID- 4137787 TI - Letter: Medicine and public health in the tropics. PMID- 4137788 TI - Letter: Meeting the need for doctors. PMID- 4137789 TI - Letter: Migraine and diet. PMID- 4137791 TI - Letter: Need for medical superintendents. PMID- 4137790 TI - Letter: Multiple sclerosis: a fever blister on the brain? PMID- 4137792 TI - Letter: Oral contraceptives, allergy, pregnancy, and depression. PMID- 4137793 TI - Letter: Oral hypoglycaemic therapy in diabetic pregnancies. PMID- 4137794 TI - Letter: Orbiviruses and gastroenteritis. PMID- 4137795 TI - Letter: Osmotic error in measurements of red-cell volume. PMID- 4137796 TI - Letter: Pairing of X and Y chromosomes. PMID- 4137797 TI - Letter: Pathogenesis of vascular proliferation in angio-immunoblastic lymphadenopathy with dysproteinaemia. PMID- 4137798 TI - Letter: Predictive value of laboratory tests. PMID- 4137799 TI - Letter: Prevention of convulsions. PMID- 4137800 TI - Letter: Prosopagnosia. PMID- 4137801 TI - Letter: Quality control of gentamicin assays. PMID- 4137802 TI - Letter: Rapid glucagon release in artificial fever. PMID- 4137803 TI - Letter: Rauwolfia derivatives and cancer. PMID- 4137804 TI - Letter: Respiratory filters in clinical practice. PMID- 4137805 TI - Letter: Retinal infarction during haemodialysis. PMID- 4137806 TI - Letter: Rifampicin and cortisone replacement therapy. PMID- 4137807 TI - Letter: Scientific medicine. PMID- 4137808 TI - Letter: Seasonal occurrence of ventricular septal defect. PMID- 4137809 TI - Letter: Self-testing reagents for diabetics. PMID- 4137810 TI - Letter: Skin wrinkling and nerve function. PMID- 4137811 TI - Letter: Skin wrinkling in cystic fibrosis. PMID- 4137812 TI - Letter: Smoking and lung cancer. PMID- 4137813 TI - Letter: Sulphasalazine-induced lung disease. PMID- 4137814 TI - Letter: SI units. PMID- 4137815 TI - Letter: ST-segment displacement after acute myocardial infarction. PMID- 4137816 TI - Letter: T lymphocytes in fulminating hepatitis. PMID- 4137817 TI - Letter: Terminology in biliary radiology. PMID- 4137818 TI - Letter: Tests for drug allergy. PMID- 4137819 TI - Letter: Tests of liver function. PMID- 4137820 TI - Letter: The megavitamin scene. PMID- 4137821 TI - Letter: Transfer-factor therapy of chronic active hepatitis. PMID- 4137822 TI - Letter: Transient hypotension after anaesthesia of peritoneum. PMID- 4137823 TI - Letter: Treatment of excessive axillary sweating. PMID- 4137824 TI - Letter: Tuberculin in rheumatoid arthritis. PMID- 4137825 TI - Letter: Unexplained tetanic spasms. PMID- 4137826 TI - Letter: Uptake of 35S-heparin by lymphocytes from cystic-fibrosis patients. PMID- 4137827 TI - Letter: Uterine pulsation as sign of early pregnancy. PMID- 4137828 TI - Letter: Vitamin A and rat embryos. PMID- 4137829 TI - Letter: Von-Willebrand-factor activity in pregnancy. PMID- 4137830 TI - Letter: What test and when? PMID- 4137831 TI - Letter: Whooping-cough vaccination. PMID- 4137832 TI - Letter: Zinc in acrodermatis enteropathica. PMID- 4137833 TI - Letter: 2,4-Diaminopyrimidines and heterozygous beta-thalassaemia. PMID- 4137834 TI - Ligneous conjunctivitis. PMID- 4137835 TI - Lobular carcinoma in situ of the breast with ductal involvement. Frequency and possible influence on prognosis. PMID- 4137836 TI - Local hemolysis plaque assay using a new method of coupling antigens on sheep erythrocytes by glutaraldehyde. PMID- 4137837 TI - Localization of the Tween 20-soluble membrane proteins of Acholeplasma laidlawii by crossed immunoelectrophoresis. PMID- 4137838 TI - Macro- and microdifferences in blood group antigens and antibodies. PMID- 4137839 TI - Macrophage immunity to vaccina virus: factors affecting macrophage immunity in vitro. PMID- 4137840 TI - Macrophages in mouse placenta: morphologic and functional identification. PMID- 4137842 TI - Methods for measurement of nitrogen oxides in automobile exhaust: a state-of-the art report. PMID- 4137841 TI - Mechanisms of pulmonary injury. PMID- 4137843 TI - Migration inhibition test in leukocytes from patients allergic to penicillin. PMID- 4137844 TI - Misinterpretation of cerebrospinal fluid Gram stain. PMID- 4137845 TI - Mitochondrial nucleoid staining with ammoniacal silver. PMID- 4137846 TI - Mitral valve replacement and aortic valve homograft: immediate postoperative care. PMID- 4137847 TI - Modulation of the assembly of immunoglobulin subunits by J chain. PMID- 4137848 TI - Morphological types of motor nerve terminals in rat hindlimb muscles, possibly innervating different muscle fiber types. PMID- 4137849 TI - Morphology and cell proliferation of subepithelial fibroblasts in adult mouse jejunum. I. Structural features. PMID- 4137850 TI - Morphology and frequency of early myocardial damage in various diseases. PMID- 4137851 TI - Mortality and water-hardness in three matched communities in Los Angeles. PMID- 4137852 TI - Motor and sensory flight neurones in a locust demonstrated using cobalt chloride. PMID- 4137853 TI - Mouse IgA myeloma proteins with alpha chain deletions: a comparison with human alpha chains with deletions. PMID- 4137854 TI - Multiple catalases of mycobacteria: differences in molecular weight. PMID- 4137855 TI - Multiple precipitation in IgA radial immunodiffusion by non-identical antigens. PMID- 4137856 TI - Murine leukemia virus group-specific antigen expression in AKR mice. PMID- 4137857 TI - Myelin breakdown and basic protein. PMID- 4137858 TI - Myocardial damage in children and its relation to coronary artery lesions. PMID- 4137859 TI - Myocardial sarcoidosis presenting as acute mitral insufficiency. PMID- 4137860 TI - Needle biopsy in diffuse lung diseases. PMID- 4137861 TI - Neonatal tolerance induced by antibody against antigen-specific receptor. AB - Specific immunologic unresponsiveness is induced by injecting adult or neonatal mice with antibody against antigen-specific receptor (antireceptor antibody). Suppression in mice treated as adults lasts several weeks, and cells from these suppressed mice respond normally in culture. In contrast, unresponsiveness induced in neonatal mice is long-lasting; cells from these mice do not respond in culture and do not affect the response of normal cells. Evidently, antireceptor antibody reversibly blocks antigen receptors in adult animals, but induces unresponsiveness in neonatal mice by depleting the clone of receptor-bearing cells. PMID- 4137862 TI - Neuronal geometry of RETZIUS cells in Hirudo medicinalis. PMID- 4137863 TI - Nomenclature for G-bands in rat chromosomes. PMID- 4137864 TI - Nonolfactory telencephalic afferents in the nurse shark (Ginglymostoma cirratum). PMID- 4137865 TI - Notes on viral oncolysis and on enhancement of tumor cell immunogenicity by adsorption of poorly infectious viruses. PMID- 4137866 TI - Ocular dominance. PMID- 4137867 TI - Oesophagogastrectomy in the treatment of malignancy of the thoracic oesophagus and cardia. PMID- 4137868 TI - Oestradiol synthesis by a human breast carcinoma. PMID- 4137869 TI - On different patterns of dendritic bundling in the cerebral cortex of the cat. PMID- 4137870 TI - On the mechanism of histamine release from pig lung in vitro induced by extracts of cotton dust. PMID- 4137871 TI - On the occurrence and morphology of Russell bodies in the dental granuloma. An evaluation of seventy-nine specimens. PMID- 4137872 TI - One-hour radioimmunoassay of serum drug concentrations, as exemplified by digoxin and gentamicin. PMID- 4137873 TI - Origin, distribution and differentiation of IgA-producing cells. PMID- 4137874 TI - Palliative resection of oesophageal carcinoma without formal thoracotomy. PMID- 4137875 TI - Parameters affecting heterogeneity of mouse anti-hapten antibody. PMID- 4137876 TI - Pathology of the Eisenmenger syndrome and primary pulmonary hypertension. PMID- 4137877 TI - Pattern formation in the imaginal discs of a temperature-sensitive cell-lethal mutant of Drosophila melanogaster. PMID- 4137878 TI - Penetration gland secretion by hexacanths of Hymenolepis diminuta;. PMID- 4137879 TI - Periapical inflammation in primary teeth and its effect on the permanent successors. PMID- 4137880 TI - Phosphorylation of myelin basic protein. PMID- 4137881 TI - Pink staining of pernicious anemia megaloblasts by alizarin red S. PMID- 4137882 TI - Place of chemotherapy in the management of malignant diseases. A retrospective study of 86 cases. PMID- 4137883 TI - Planning the operation of audiovisual aids in pathology. The search for optimal learning methods. PMID- 4137884 TI - Plasma digoxin after parenteral administration. Local reaction after intramuscular injection. PMID- 4137885 TI - Plasma fractionation in the United States. A review for clinicians. PMID- 4137886 TI - Plasma protein pattern in acute infectious diseases. PMID- 4137887 TI - Plasma-gastrin and acid secretion in patients with peptic ulceration. PMID- 4137888 TI - Potentiation of helper T cell function in IgE antibody responses by bacterial lipolysaccharide (LPS). PMID- 4137889 TI - Preoperative anaesthetic assessment clinic. PMID- 4137890 TI - Preparation of human angiotensinogen for plasma renin concentration assay. PMID- 4137891 TI - Preparation of iodinated tyrosine methyl ester of estradiol for radioimmunoassay. PMID- 4137892 TI - Prescribing: a programme emphasising benefits. PMID- 4137893 TI - Prevention and the handicapped child. PMID- 4137894 TI - Price of prostatectomy. AB - Three different urological units found that transurethral prostatectomy required a hospital stay at least one week shorter than open Millin or transvesical prostatectomy. By making transurethral resection more widely available there could be a substantial financial saving; but more surgeons would have to specialize in urology. PMID- 4137895 TI - Primary immunodeficiency. PMID- 4137896 TI - Production of an immunoglobulin-binding factor (IBF) by antigen-stimulated lymph node lymphocytes. PMID- 4137897 TI - Propanoic acid-ferric oxide hydrosols. Differential cell surface binding and its relation to membrane lipid. PMID- 4137898 TI - Protein and RNA synthesis in human proliferative endometrium in organ culture and the effect of progesterone. PMID- 4137899 TI - Protein synthesis in cells of various parts of the exocrine epithelium of the rat pancreas. PMID- 4137900 TI - Protonmotive force in fermenting Streptococcus lactis 7962 in relation to sugar accumulation. PMID- 4137901 TI - Psychoanalysis, the behavioral therapies, and the world of the future. PMID- 4137902 TI - Purification of influenza viruses using disulphide-linked immunosorbents derived from rabbit antibody. PMID- 4137903 TI - Purkinje fibers of sheep papillary muscle: occurrence of discontinuous fibers. PMID- 4137904 TI - Quantitative histological changes in osteoarthritic hip cartilage. Morphometric analysis of 29 osteoarthritic and 26 normal human femoral heads. PMID- 4137905 TI - Rapid antigenic typing of herpesvirus hominis isolates on the surface of infected cells by kinetic binding of 125I-labeled HVI antibodies. PMID- 4137906 TI - Rapid bacteriological diagnosis of pyogenic meningitis by latex agglutination. PMID- 4137907 TI - Rapid microspectrofluorimetry for biochemical and metabolic studies in single living cells. PMID- 4137908 TI - Rapid screening test for detection of elevated myo-inositol levels in human blood serum. PMID- 4137909 TI - Reaction of cardiolipin and phosphatidylinositol antisera with phospholipid antigens. PMID- 4137910 TI - Recurrent aphthous stomatitis and body reactivity. PMID- 4137911 TI - Regression of diet-induced fatty streaks in rhesus monkeys. PMID- 4137912 TI - Regression of stomatitis nicotina in persons with a long-standing habit of reverse smoking. Morphologic evidence of the role of ducts. PMID- 4137914 TI - Relationship of carcinoembryonic antigen to blood substances A and i: evidence that the antigenic sites are on different molecules. PMID- 4137913 TI - Relationship between antigen induced histamine release and cyclic AMP level in human leukocytes. PMID- 4137916 TI - Rhabdomyosarcomas induced by rous sarcoma virus in golden hamsters. PMID- 4137915 TI - Retention of matrix density in adrenergic vesicles after extensive norepinephrine depletion. PMID- 4137917 TI - Robert John McNeill Love. PMID- 4137918 TI - Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia. PMID- 4137919 TI - RNA metabolism in the brain. PMID- 4137920 TI - Sea-blue histiocytosis in hyperlipoproteinemia (cytomorphological, clinical and pathogenetic aspects). PMID- 4137921 TI - Selective amyloid staining as a function of amyloid composition and structure. Histochemical analysis of the alkaline Congo red, standardized toluidine blue, and iodine methods. PMID- 4137922 TI - Separation of t-RNAs by two-dimensional polyacrylamide gel electrophoresis. PMID- 4137923 TI - Serum creatinine, urea, and protein level changes in hydatidiform mole. PMID- 4137924 TI - Serum lipoproteins and the intravenous fat tolerance test in hypothyroid patients before and during substitution therapy. PMID- 4137925 TI - Serum protein fractions as determined by cellulose actate electrophoresis in schistosoma mattheei infested sheep. PMID- 4137926 TI - Short-term direct, and macrophage stimulated, bactericidal properties of antigen activated lymph node cell culture fluids. PMID- 4137927 TI - Silico-mycobacterial disease in sandblasters. PMID- 4137928 TI - Sister chromatid exchanges, indices of human chromosome damage and repair: detection by fluorescence and induction by mitomycin C. AB - Sister chromatid exchanges in chromosomes from human lymphocytes grown two replication cycles in medium containing 5-bromodeoxyuridine can be detected by fluorescence microscopy after staining with the bisbenzimidazole dye 33258 Hoechst. These exchanges are much more frequent than chromosome or chromatid breaks and appear to be partly but not entirely due to 5-bromodeoxyuridine incorporation. Sister chromatid exchanges are extremely sensitive indicators of chromosome damage produced by DNA cross-linking agents such as mitomycin C. Significant increases in the sister chromatid exchange frequency occur with 3 ng/ml of mitomycin C; higher concentrations of mitomycin C induce further sister chromatid exchanges. Comparatively few gross chromosomal aberrations are seen in cells exhibiting as many as one hundred or more sister chromatid exchanges. Most of the damage caused by mitomycin C to chromosomal DNA is apparently repaired without detectable changes in chromosome morphology. Analysis of sister chromatid exchanges may permit more sensitive detection of damage to DNA caused by other agents than has previously been possible by classical cytological techniques. PMID- 4137929 TI - Somatic chromosomes of the African white-tailed rat. PMID- 4137930 TI - Spasmodic torticollis: treatment by feedback display of the EMG. PMID- 4137931 TI - Special characteristics of the IgA2 subclass. PMID- 4137932 TI - Specific demonstration of the human hypophyseal adrenocortico-melanotropic (ACTH MSH) cell. PMID- 4137933 TI - Specific membrane properties of cat motoneurones. AB - 1. Electrophysiological properties of cat motoneurones were measured using intracellular electrodes, after which Procion dye was injected iontophoretically into the neurone through the recording pipette.2. Histological procedures were chosen to minimize changes in neuronal morphology. Reconstructed motoneurones had more dendritic branches and larger surface areas than the Golgi-stained motoneurones of earlier reports.3. The sum of the 3/2 power of the dendritic diameters (the dendritic trunk parameter; Rall, 1959) of the reconstructed motoneurones was found to decrease with distance from the soma. Thus, the dendritic tree is not satisfactorily approximated by a non-tapering membrane cylinder.4. A computational technique was developed to allow calculation of the specific resistance (R(m)) of the membrane using the measured value of the input resistance of the motoneurone and a more detailed approximation of the dendritic tree. These calculations indicate that the average resting value of dendritic R(m) is at least 1800 Omega cm(2). The specific membrane capacity, calculated assuming uniform R(m), ranged between 2-3 muF/cm(2). PMID- 4137935 TI - Specificity of antibodies to Streptococcus mutans; significance in inhibition of adherence. PMID- 4137934 TI - Specific positive selection of lymphocytes reactive to strong histocompatibility antigens. AB - Selected populations of thymus-derived (T) rat lymphocytes having specific immunological reactivity to chosen histocompatibility (H) alloantigens are found among the cellular products of the mixed lymphocyte interaction (MLI). Such specific selection seems to depend on (a) the antigen-induced proliferation of specific H antigen reactive cells (HARC), and (b) the disappearance of nonreactive cells from the cultures. When the surviving cells from this lymphocyte-antigen interaction are transferred into thymectomized, X-irradiated, marrow-reconstituted syngeneic recipients (B rats) which lack detectable T lymphocyte functions, the lymphocyte populations subsequently recovered from the hosts possess the capacity to react in the MLI and in the graft-vs.-host (GVH) reaction, and the reactions have specificity for the original priming alloantigens. In addition, these findings identify the cell that reacts in the MLI with the GVH reactive cell. PMID- 4137936 TI - Specificity of cell-mediated transplantation reactions. I. Studies with the technique of inhibition of migration and an assay of tumour immunity in vivo. PMID- 4137937 TI - Specificity of cell-mediated transplantation reactions. II. Studies with a sensitive assay of cell-mediated cytotoxicity. PMID- 4137939 TI - Spectrophotometric determination of naphazoline and phenotolamine in some pharmaceutical preparations using sodium nitroprusside. PMID- 4137938 TI - Specificity of the DNA product of RNA-dependent DNA polymerase in type C viruses: 3. Analysis of viruses derived from Syrian hamsters. AB - DNA transcripts were prepared from three related viruses of hamster and analyzed by interviral hybridization and by reaction with cellular DNA. A virus (G-HaLV), isolated from a dimethylbenzanthraceneinduced tumor cell in Graffi hamsters, contained nucleic acid sequences highly specific for hamster cell DNA and did not react with mouse cell DNA nor did its transcript show homology (<5%) with mouse or rat viral RNAs. The hamster-specific sarcoma virus, B-34, isolated by Bassin and coworkers from tumors induced by the Harvey strain of murine sarcoma virus, contained mouse-, hamster-, and possibly rat-specific sequences. B-34 transcripts were predominantly mouse-specific. GLOH(-), a lymphomagenic virus derived by dilution beyond the transforming endpoint of a hamster-specific sarcoma virus obtained from tumors induced by the Gross pseudotype of murine sarcoma virus, also contained hamster- and mouse-specific sequences. Only a portion of its hamster sequence (about 50%) was shared with B-34 and G-HaLV viruses. As expected, transcripts of GLOH(-) virus were reactive with mouse and hamster cellular DNA. PMID- 4137940 TI - Sperm immunology, infertility, and fertility control. PMID- 4137941 TI - Spontaneous sister chromatid exchanges detected by a BUdR-labelling method. PMID- 4137942 TI - Staged palliative resection of recurrent carcinoma of the neck using an extra anatomic carotid bypass. PMID- 4137943 TI - Staining of histones on polyacrylamide gels with amido black and fast green. PMID- 4137944 TI - Stimulatory immunotherapy in mammary cancer. PMID- 4137945 TI - Structure of the O-glycosidically linked carbohydrate units of fetuin. PMID- 4137946 TI - Studies on monoclonal antibodies. II. Immune complex (IgM-IgG) cryoglobulinemia: the mechanism of cryoprecipitation. PMID- 4137947 TI - Studies on the action of the calcium ionophore A 23187 on isolated rat mast cells. PMID- 4137949 TI - Studies on the human T-lymphocyte population. I. The development and characterization of a specific anti-human T-cell antibody. PMID- 4137948 TI - Studies on the biological and antigenic properties of ESP-1 type C virus particles. PMID- 4137950 TI - Studies on the human T-lymphocyte population. II. The use of a T-cell specific antibody in the partial isolation and characterization of the human lymphocyte receptor for sheep red blood cells. PMID- 4137951 TI - Studies on the influence of calcium in the anaphylactic histamine release from isolated rat mast cells. PMID- 4137952 TI - Studies on the nature of the abnormality of B cell differentiation in avian lymphoid leukosis: production of heterogeneous IgM by tumor cells. PMID- 4137953 TI - Studies on the status of arginine residues in cobrotoxin. PMID- 4137954 TI - Studies on transforming activities from human solid tumor cells following co cultivation with human leukemic bone marrow cells. PMID- 4137955 TI - Surface coats of the mouse blastocyst and uterus during the preimplantation period. PMID- 4137956 TI - Surface immunoglobulins of rat immunocytes: quantitation and fate of cell-bound peroxidase-labeled antibody and Fab fragment. PMID- 4137957 TI - Surface structure of mouse mammary tumor virus. PMID- 4137958 TI - Survey of recent studies on mechanism and significance of delayed (cellular)-type hypersensitivity. PMID- 4137959 TI - Synthesis of DNA complementary to cellular slime mold messenger RNA by reverse transcriptase. PMID- 4137961 TI - Teacher and distinguished pupil: William Henry Welch and George Hoyt Whipple. PMID- 4137960 TI - Systematics of RNA tumor viruses and virus-like particles of human origin. AB - [(3)H]DNA copies of avian, feline, murine, and primate RNA tumor virus genomes were synthesized in vitro by an RNA-dependent DNA polymerase reaction. These DNAs were hybridized to 60-70S RNA that had been purified from the viruses. The amount of the [(3)H]DNA hybridized yielded a measure of the genetic relatedness among the DNA preparations synthesized by the viruses. When many combinations of DNA and RNA were analyzed, the pattern of hybridization showed in some cases that the DNA copies of the viral RNA were related to each other in the same way that the natural hosts of the viruses are phylogenetically related. This pattern was observed only among the RNA leukemia viruses. The sarcoma component in sarcoma leukemia viruses from rats and primates appeared to be unusually closely related. The mouse mammary carcinoma virus and two unclassified viruses (MPMV and Visna) appeared to be genetically distinct.A similar analysis of DNA synthesized by an RNA-dependent DNA polymerase associated with a viral-like particle obtained from the cytoplasm of human leukemic white blood cells demonstrated that this DNA occupied a space in the affinity pattern of leukemia viruses which is expected of a nucleic acid from a primate-type-C RNA tumor virus. This observation strengthens earlier evidence that components of RNA tumor viruses are associated with human leukemia. PMID- 4137962 TI - Teaching medical-surgical nursing by concepts. PMID- 4137963 TI - Tensile yield in bone. PMID- 4137964 TI - Testing the potency of smallpox vaccines, anti-smallpox immune sera and immunoglobulins with the use of own reference vaccine and standard immunoglobulin. PMID- 4137965 TI - The action of nicotinamide on the release of histamine. PMID- 4137966 TI - The active sites of immunoglobulin molecules. PMID- 4137967 TI - The alpha2-macroglobulin level in cerebrospinal fluid; a parameter for the condition of the blood-CSF barrier. PMID- 4137968 TI - The antigenic determinant of fibrin(ogen) measured with agglutination inhibition immunoassays. AB - Agglutination inhibition immunoassays using antifibrinogen antiserum measure an antigenic determinant of fibrinogen which is located on the fragment D parts of this molecule. This antigenic determinant of fragment D, in contrast to others, does not form an immune precipitate with antifibrinogen antiserum. Upon very extensive hydrolysis by plasmin, this antigenic determinant has a reduced affinity for its antibody. PMID- 4137969 TI - The binding of asialo-glycoprotein to isolated Golgi apparatus. PMID- 4137970 TI - The cellular and molecular basis of immunological tolerance. PMID- 4137971 TI - The chemical elements and human morbidity--water, air and places--a study of natural variability. PMID- 4137972 TI - The complexity of the HL-A gene product I: study of a serum produced against HL A5 in an HL-A semi-identical situation. PMID- 4137973 TI - The diagnostic value of the NBT-test in the case of febrile diseases. PMID- 4137974 TI - The encephalitogenic dose response in guinea pigs of the tryptophan region of myelin basic protein. PMID- 4137975 TI - The establishment of systemic immunity following antigenic stimulation of the lymphoid tissue of the gastrointestinal mucosa. PMID- 4137976 TI - The fetus at risk. PMID- 4137977 TI - The genetic control of the immune response to different antigenic determinants within the synthetic polypeptide poly(His, Glu)-polyPro-polyLys. PMID- 4137978 TI - The hemocytes of a scorpion Palamnaeus swammerdami. PMID- 4137979 TI - The hemocytes of an lsopod Ligia exotica Roux. PMID- 4137980 TI - The hinge peptide of an IgA2m(2) myeloma protein. PMID- 4137981 TI - The induction and characterization of secretory IgA antibodies. PMID- 4137982 TI - The innervation of the trapezius muscle. An electrophysiological study. PMID- 4137983 TI - The karyotype of the pig. PMID- 4137984 TI - The lack of estrogen binding by human alpha-fetoprotein. PMID- 4137985 TI - The management of chronic pain syndromes in the upper extremity. PMID- 4137986 TI - The mechanism of breakdown of immune tolerance to a protein antigen in rabbits. PMID- 4137987 TI - The mechanism of the inhibitory action of zinc on histamine release from mast cells by compound 48-80,. PMID- 4137988 TI - The natural mediator for PMN emigration in inflammation. II. Common antigenicity of leucoegresin with immunoglobulin G. PMID- 4137989 TI - The natural mediator for PMN emigration in inflammation. 3. In vitro production of a chemotactic factor by inflammatory SH-dependent protease from serum immunoglobulin G. PMID- 4137990 TI - The nature of nuclear ribonucleoprotein particles containing virus-specific RNA. PMID- 4137992 TI - The nephrotic syndrome of infancy. PMID- 4137991 TI - The nephropathy of experimental hepatosplenic schistosomiasis. AB - The glomerular lesions induced in 10 chimpanzees infected with variable numbers of Schistosoma japonicum cercariae were studied by means of light and electron microscopy and fluorescent antibody technic. Ten animals served as controls; 5 were uninfected and 5 were only lightly infected. The animals were observed for periods ranging from 3 to 17 months, and by the time of sacrifice, all had developed advanced liver fibrosis. In general, the degree of glomerular injury was related to infection intensity and degree and duration of portal liver fibrosis. Some animals had terminal BUN elevation and slight proteinuria. By light and electron microscopy, in the initial stages, only part of the glomeruli were involved and exhibited mesangial matrix expansion and mesangial cell proliferation with intracellular hyaline droplets. At later stages, a larger number of glomeruli were affected and exhibited diffuse hypercellularity, glomerular basement thickening, mesangial sclerosis and less often, focal necrosis, crescent formation, synechiae and global hyalinization. In addition, there were discrete electron-dense deposits localized in the mesangial area in some glomeruli. Immunofluorescent studies utilizing antisera to chimpanzee gamma globulin and complement (C3) and to human properdin disclosed only faint deposits of C3, apparently in mesangial areas. The association of hepatosplenic schistosomiasis and nephropathy, the possible role of schistosomal antigen and the mechanism(s) of such glomerular injuries are reviewed and compared with the disease in humans and other host species infected with Schistosoma. PMID- 4137993 TI - The neuronal organization of cerebellar lobe C1 in the mormyrid fish Gnathonemus Petersii (teleostei). PMID- 4137994 TI - The origin of monomeric and polymeric forms of IgA in man. PMID- 4137995 TI - The production of experimental glomerulonephritis in the rat. PMID- 4137996 TI - The rat mast cell degranulation assay as an in vitro allergy test. PMID- 4137997 TI - The relationship between changes in cell wall composition and the establishment of polarity in Fucus embryos. PMID- 4137998 TI - The relationship of ventricular asynergy in coronary artery disease to ventricular premature beats. PMID- 4137999 TI - The relevance of RNA tumor viruses to human cancer. PMID- 4138000 TI - The rise of the filtering operations. PMID- 4138001 TI - The role of cellular interaction in differentiating between the occurrence of immunological tolerance and immunity following antigenic challenge. PMID- 4138002 TI - The search for meaning in renal transplantation. PMID- 4138003 TI - The sliding lens paradox or the unexpected effect of longitudinal ("to-and-fro") motion of plus spectacle lenses. A treatise on lens effectivity. PMID- 4138004 TI - The social world of individuals. PMID- 4138005 TI - The staining pattern of collagen fibrils. I. An analysis of electron micrographs. PMID- 4138006 TI - The staining pattern of collagen fibrils. II. A comparison with patterns computer generated from the amino acid sequence. PMID- 4138008 TI - The structure of rat liver mitochondria: a reevaluation. PMID- 4138007 TI - The strange cross-reaction of menadione (vitamin K3) and 2,4-dinitrophenyl ligands with a myeloma protein and some conventional antibodies. AB - To explore the possibility that the affinity of some myeloma proteins for 2,4 dinitrophenyl (DNP) ligands is the consequence of a "strange" (i.e., unexpected) cross-reaction for more natural ligands, a variety of substances (primarily derivatives of purines, pyrimidines, naphthaquinone) were tested for ability to block the binding of [(3)H]-epsilon-DNP-L-lysine by protein 315, an IgA mouse myeloma protein with high affinity for DNP ligands. The most impressive inhibiting activity was observed with 2-methyl-1,4-napthaquinone (menadione, vitamin K(3)). The affinity (intrinsic association constant) of protein 315 for menadione was 5 x 10(5) L/M (at 4 degrees C). Because the same affinity was measured in direct-binding assays (e.g., equilibrium dialysis) and in an indirect one based on the assumption of competitive binding with DNP-lysine, it is likely that menadione and DNP bind at overlapping sites in the protein's combining region. This conclusion is supported by molecular models which reveal some common structural features in these ligands. Hence it is not surprising that antinitrophenyl antibody preparations, raised by conventional immunization procedures (anti-2,4-DNP; anti-2,6-DNP; anti-2,4,6-TNP) also bind menadione with considerable affinity. As with DNP ligands, when menadione binds to protein 315 or to conventional antinitrophenyl antibodies, some of the protein's tryptophan fluorescence is quenched, there is a change in the ligand's absorption spectrum (hypochromia and/or red shift), and the binding is temperature-dependent (exothermal). PMID- 4138009 TI - The susceptibility of the fetus and child to chemical pollutants. Chemicals in human teratogenesis and transplacental carcinogenesis. PMID- 4138010 TI - The susceptibility of the fetus and child to chemical pollutants. Nature and sources of pollutants. PMID- 4138011 TI - The ultrastructure and permeability for colloidal carbon of intestinal submucosal arterioles in rats. PMID- 4138012 TI - The uninvolved psoriatic epidermis. PMID- 4138013 TI - The use of a sensitive micronephelometer in the estimation of antigens and precipitating antibodies. PMID- 4138014 TI - The use of the basic fuchsin stain in the recognition of early myocardial ischaemia. PMID- 4138015 TI - The value of the morphological and enzyme histochemical investigation in ovarian biopsies of twenty-two patients with menstrual disorders. PMID- 4138016 TI - The vestibular aqueduct and the para-vestibular canal. An anatomic and roentgenologic investigation. PMID- 4138017 TI - The IgA antibody-forming cell response in the rabbit submandibular gland following several different methods of immunization. PMID- 4138018 TI - Three contributions of lectins to the understanding of specific agglutination and precipitation. PMID- 4138019 TI - Three-dimensional reconstruction of the pericellular nests (baskets) of the motor (area 4) and visual (area 17) areas of the human cerebral cortex. A Golgi study. PMID- 4138020 TI - Topology of the outer segment membranes of retinal rods and cones revealed by a fluorescent probe. AB - When N,N'-didansyl cystine binds to the cell membranes of vertebrate rods and cones its fluorescence efficiency increases about 20-fold. The entire outer segments of living cones become brilliantly fluorescent. Stained live rods, as well as most freshly detached outer segments, are only weakly fluorescent, but they become brightly fluorescent within a few seconds if their plasma membranes are osmotically ruptured. The difference in staining of rod and cones suggests that disk membranes of rods are not continuous with the plasma membranes are osmotically ruptured. The difference in staining of rod and cones plasma membrane on outer segments of photoreceptors in electrophysiological and biochemical experiments, and to study the infolding pattern of rod and cone disks. PMID- 4138021 TI - Transcription and translation of viral RNA in cells transformed by RNA tumor viruses. PMID- 4138022 TI - Transfer of delayed hypersensitivity in rats. PMID- 4138023 TI - Transmission of proteins from mother to conceptus in the grey squirrel (Sciurus carolinensis). PMID- 4138024 TI - Transumbilical balloon atrial septostomy in 16 infants with transposition of the great arteries. PMID- 4138025 TI - Treatment of urinary retention. AB - In 50 patients retention of urine due to adenomatous enlargement of the prostate was relieved, in most cases by intraprostatic injections given for varying periods of time. No complications were encountered. Subsequently, some of the patients who did not respond adequately, and whose medical conditions improved, underwent prostateceomy. Histologically the removed prostates showed coagulation necrosis, with or without haemorrhage, but no inflammatory reaction. PMID- 4138026 TI - Triple pathway for induction of chemotaxis in neutrophil leucocytes by guinea-pig immune complexes of different Ig classes. PMID- 4138027 TI - Tumor growth in the guinea pig: alpha globulin changes associated with lymphocyte suppression. PMID- 4138028 TI - Type C viruses of baboons: isolation from normal cell cultures. PMID- 4138029 TI - Type-specific antibodies in human Chlamydia trachomatis infections of the eye. PMID- 4138030 TI - U.S. citizens studying medicine abroad. PMID- 4138031 TI - Ultrastructural localization of cholinesterase activity in the developing rat retina. PMID- 4138033 TI - Ultrastructure of bile canaliculi, with special reference to the surface coat and the pericanalicular web. PMID- 4138032 TI - Ultrastructural staining of thin sections with iron hematoxylin. PMID- 4138034 TI - Ultrastructure of the erythrocytes in beta-thalassemia. PMID- 4138035 TI - Usefulness of blood levels of antiepileptic drugs. PMID- 4138037 TI - Visceral viewpoints. My kingdom for a camera--some comments on medical technology. PMID- 4138036 TI - Vascular basement membrane changes in diabetic retinopathy. Montgomery lecture, 1973. PMID- 4138038 TI - Visualization of deoxyribonucleic acid molecules by protein film adsorption and tantalum-tungsten shadowing. PMID- 4138040 TI - Whipple disease: light and electron microscopy study. PMID- 4138039 TI - Vitamin K and the biosynthesis of prothrombin. IV. Isolation of peptides containing prosthetic groups from normal prothrombin and the corresponding peptides from dicoumarol-induced prothrombin. PMID- 4138041 TI - Why admit abortion patients? PMID- 4138042 TI - 12-(9-Anthroyl)-stearic acid and atebrin as fluorescence probes for energetic states of chloroplasts. PMID- 4138043 TI - 17-beta-oestradiol and the fibrinolytic activity on vein walls. PMID- 4138044 TI - Case against the use of d-tubocurarine in operant studies of the cardiovascular system. PMID- 4138045 TI - Uses and abuses of thyroid function tests. PMID- 4138046 TI - Fast and simple identification of adipose tissues in situ with dithizon. PMID- 4138047 TI - Test and teach number one. Myxoid liposarcoma of the thigh. PMID- 4138048 TI - Diet and the geographical distribution of multiple sclerosis. PMID- 4138049 TI - Some aspects of the release of the adrenergic transmitter. PMID- 4138050 TI - Cell border demarcation in the scanning electron microscope by silver stains. PMID- 4138051 TI - Mast cell population density in hamster gingiva. PMID- 4138052 TI - Some characteristics of the immune response to sporozoites of simian and human malaria. PMID- 4138053 TI - [The chorionic membrane of the human placenta]. PMID- 4138055 TI - [New cytogenetic methods in hematological clinic]. PMID- 4138054 TI - Time course of histamine release and edema formation in the rat paw after thermal injury. PMID- 4138056 TI - [New data on the viral etiology of cancer]. PMID- 4138057 TI - [The diagnostic value of serum acid phosphatases in carcinoma of the prostate (author's transl)]. PMID- 4138058 TI - [The diagnostic value of the TRH test in thyroid disease]. PMID- 4138059 TI - [The external rotation of the lower limb in normal and hemiplegic individuals (author's transl)]. PMID- 4138060 TI - High frequency of T lineage lymphocytes in nude mouse spleen. PMID- 4138061 TI - Disc gel electrophoresis. A technique involving fluorescent staining prior to separation. PMID- 4138063 TI - Cold lability of Bacillus cereus bacteriophage CP-51. AB - Phage CP-51 was rapidly inactivated when stored at the usual refrigerator temperatures (2 to 4 C) and even more rapidly when exposed to 0 C. The loss in viability resulting from exposure to cold appeared to correlate with the increase in number of phage particles having contracted tails. High concentrations (0.01 M) of Mg(2+), Ca(2+), or Mn(2+) stabilized the phage considerably, but even in the presence of these divalent cations, it was much less stable at 0 C than at 15 C. PMID- 4138062 TI - [The influence of air pollution on the paraffin content of the skin surface lipids (author's transl)]. PMID- 4138064 TI - [The lymphocyte blast-transformation reaction under the influence of collagen in osteochondrosis patients with a radicular syndrome]. PMID- 4138065 TI - [The morphology of the CNS in carbon tetrachlorid poisoning. Histological findings in the cerebellum of cross-breed rabbits (part III) (author's transl)]. PMID- 4138066 TI - [The ocular risks of treatment of Basedow's disease (author's transl)]. PMID- 4138067 TI - Role of energy metabolism in histamine release. A study on isolated rat mast cells. PMID- 4138068 TI - Role of the compensatory pause in the production of concealed bigeminy. PMID- 4138069 TI - Role of H-2 lymphocyte-defined and serologically-defined components in the generation of cytotoxic lymphocytes. AB - The cell-mediated lympholytic capability of mouse spleen cells stimulated in mixed lymphocyte culture is determined by lymphocyte-defined (LD) and serologically-defined (SD) antigenic differences present during sensitization. Cells which are activated by LD differences alone are markedly less effective in causing lysis of target cells. This lack of cytotoxicity is shown to be, at least in part, due to the inability of LD differences to allow the efficient generation of cytotoxic lymphocytes. SD antigens not only serve as good targets for CML but are also shown to be important for the generation of cytotoxic lymphocytes during the mixed lymphocyte culture. PMID- 4138071 TI - Left or right hepatic duct? PMID- 4138070 TI - Role of T lymphocytes in the humoral immune response. I. Proliferation of B lymphocytes in thymus-deprived mice. PMID- 4138072 TI - [The pathology of various chronic fibrotic lung diseases (with particular regard to clinical cases)]. PMID- 4138074 TI - Side reactions of chloramphenicol in mouse erythroblasts. PMID- 4138073 TI - Skin prolyl hydroxylase in patients with obstructive jaundice. PMID- 4138075 TI - Late results following cryosurgery of the prostate in 97 high risk patients. PMID- 4138076 TI - [The results of treatment of thyrotoxic heart disease (author's transl)]. PMID- 4138078 TI - Zinc therapy in acrodermatitis enteropathica. PMID- 4138077 TI - Cell surface modification in the treatment of experimental cancer: neuraminidase or concanavalin A. PMID- 4138079 TI - [The treatment of dermatomyositis]. PMID- 4138080 TI - Late urinary-tract infection after renal transplantation. PMID- 4138081 TI - [The use of gestagens in the treatment of infertility in the cow (collection of reports of unusual cases: clinical reports) (author's transl)]. PMID- 4138082 TI - [The value of plethysmography in Sudeck's dystrophy (author's transl)]. PMID- 4138084 TI - 1975 National Children's Dental Health Week special aids. Bureau of Dental Health Education. PMID- 4138083 TI - [New viewpoints on the etiology of Sudeck's syndrome]. PMID- 4138086 TI - Drug-induced lupus erythematosus syndrome. Immuno-pathological, electronmicroscopical and serological studies. PMID- 4138085 TI - Cost-effectiveness relationships in odor control. PMID- 4138087 TI - Cell-mediated autohypersensitivity in psoriasis. In vitro tests with extracts from psoriatic skin and scales. PMID- 4138088 TI - Long-term assessment of cyclophosphamide therapy for nephrosis in children. PMID- 4138089 TI - Long-term oral antiarrhythmic therapy with aprindine (AC 1802). PMID- 4138090 TI - Long-time treatment of intermittent claudication with vitamin E. PMID- 4138091 TI - Anti-T agglutinin in cirrhosis of the liver. PMID- 4138092 TI - User's guide to some new tests for hepatitis-B antigen. PMID- 4138093 TI - The "Doctoress" on a donkey: women health officers in nineteenth century Egypt. PMID- 4138094 TI - Visna and maedi viruses in tissue culture. PMID- 4138095 TI - Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury. PMID- 4138096 TI - Gamma globulins in pre-colostral piglet serum. PMID- 4138097 TI - "Catabolic" loss of body nitrogen in response to surgery. PMID- 4138098 TI - Collaborative study of the determination of Geotrichum mold in selected canned fruits and vegetables. PMID- 4138099 TI - Intracellular accumulation of oncornaviruses in continous human cell lines. PMID- 4138100 TI - Coxsackie B4 viruses and atrial myxoma. PMID- 4138101 TI - Characterization of human carcinoembryonic antigens. PMID- 4138102 TI - Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidine. PMID- 4138103 TI - Characterization of reverse transcriptase and RNase H from friend-murine leukemia virus. PMID- 4138104 TI - Characterization of the antibody production in rabbits induced by streptococcal group A and C carbohydrate antigens. I. Evidence for lact of correlation between magnitude of immune response, degree of antibody restriction, and immunoglogulin allotype. PMID- 4138105 TI - Characterization of the antibody production in rabbits induced by streptococcal group A and C carbohydrate antigens. II. Evidence that the appearance of an antibody response of restricted heterogeneity is accompanied by an anti-antibody production. PMID- 4138106 TI - Characterization of R-type vitamin B12-binding proteins by isoelectric focusing. I. The relationship between transcobalamin I, transcobalamin III and the granulocyte R protein. PMID- 4138107 TI - Glucagon control of fasting glucose in man. PMID- 4138108 TI - [Obtaining and clinical use of human immunoglobulins]. PMID- 4138110 TI - On waking screens. PMID- 4138109 TI - Explaining the unexpected abnormal results of biochemical profile investigations. PMID- 4138111 TI - Rectal carcinoid and rectal adenocarcinoma: a case report and review of the literature. PMID- 4138112 TI - Foetal origin of transferrin in mouse amniotic fluid. PMID- 4138113 TI - Medial pulvinar afferents to frontal eye fields in rhesus monkey demonstrated by horseradish peroxidase. PMID- 4138114 TI - [Local therapy in the oral and pharyngeal cavitities]. PMID- 4138115 TI - [Local use of histaglobin in vasomotor rhinitis]. PMID- 4138116 TI - Prevalence and prognostic value of ventricular dysrhythmias in patients with healed myocardial infarction. PMID- 4138117 TI - Mortality in areas containing natural fluoride in their water supplies, taking account of socioenvironmental factors and water hardness. PMID- 4138118 TI - [Dynamics of immunological indices under the effect of specific desensitization therapy in patients with recurrent aphthous stomatitis]. PMID- 4138119 TI - Histamine content of tracheal and lung tissue as a function of age in rats. PMID- 4138120 TI - Histamine release from isolated rat mast cells due to glycoprotein from Candida albicans in vitro. PMID- 4138121 TI - Histamine storage and release. PMID- 4138122 TI - RNA and DNA forms of the genetic material of C-type viruses and the integrated state of the DNA form in the cellular chromosome. PMID- 4138123 TI - Variant (Prinzmetal's) form of angina pectoris manifesting in complicating ventricular extrasystoles. PMID- 4138124 TI - [Advantages and inconveniences of uranyl acetate in comparative virology: study of 4 tailed bacteriophages]. PMID- 4138125 TI - Intraocular use of butyl-2-cyanoacrylate in retinal detachment surgery. A preliminary report. PMID- 4138126 TI - Therapeutic effectiveness and plasma levels of a new antidysrhythmic drug: aprindine. PMID- 4138127 TI - The application of acridine orange staining to quantitate low levels of Babesia divergens parasitaemias. PMID- 4138128 TI - Comparative investigation of protein concentration in serum and synovial fluid. PMID- 4138129 TI - Comparative study of 240 cases of cryosurgery using nitrogen protoxide and liquid nitrogen as coolant. PMID- 4138130 TI - [Apparatus combination for the kinetic determination of lactate dehydrogenase as based on Wagenknecht's color test]. PMID- 4138131 TI - Margaret Mary Basden. PMID- 4138132 TI - Primary amyloidosis with polyneuropathy. Some aspects on the histopathological diagnosis ante mortem based on studies of biopsy specimens from 30 familial and non-familial cases. PMID- 4138133 TI - Release of skin reactive factor by human lymphocytes. An in vitro correlate of cellular immunity. PMID- 4138134 TI - New aspects of oriented binding of diazo complexes on amyloid fibrils and other fibrillar protein structures. PMID- 4138135 TI - The assay of urinary thyroid hormones for assessing thyroid function. PMID- 4138136 TI - Ultrastructural changes in the normal human lens capsule from birth to old age. PMID- 4138137 TI - Ultrastructural studies of the argyrophil reaction in alpha1 cells in human pancreatic islets. PMID- 4138138 TI - Ultrastructural study of epithelial and connective gingival reattachment in man. PMID- 4138139 TI - Ultrastucture of the surface of Rickettsia prowazeki and Rickettsia akari. AB - Negative-contrast electron microscopy revealed that the outer layer of the envelope of rickettsiae is composed of a matrix of tetragonally arranged subunits. The layer projects approximately 7 nm from the cell wall. It is suggested that this outer layer is analogous to the structure considered capsule like in morphology. PMID- 4138140 TI - The ataxic (cerebellar) form of Creutzfeldt-Jakob disease. PMID- 4138141 TI - Sulfated acid mucopolysaccharides in the cortical granules of eggs. Effects of quaternary ammonium salts on fertilization. PMID- 4138142 TI - Isolation and characterization of Golgi apparatus and membranes from rat liver. PMID- 4138143 TI - Isolation and identification of soluble skin-reactive membrane antigens of malignant and normal human breast cells. PMID- 4138145 TI - Isolation of plant nuclei. PMID- 4138144 TI - Isolation of epidermal desmosomes. AB - A method is reported for the isolation of desmosomes in a high yield and of a purity suitable for biochemical analysis. The procedure utilizes the selective solubilizing action of citric acid-sodium citrate (CASC) buffer, pH 2.6, on the non-cornified layers of cow nose epidermis, followed by discontinuous sucrose density gradient centrifugation. Electron microscopy with both thin sections of pellets and unfixed spread preparations reveals that after centrifugation, desmosomes are located mainly at the 55-60% sucrose interface. In the desmosome preparation thus obtained, the characteristic desmosome structure is well preserved, showing the midline, unit membranes, and dense plaques. Furthermore, removal of the epidermal filament bundles by the solubilizing action of CASC buffer has revealed a finely filamentous layer on the cytoplasmic surface of the plaques. The dimensions, location, and appearance of this layer correspond with those of the "connecting component" which has been previously suggested as being responsible for the attachment of epidermal filament bundles to the desmosome. PMID- 4138146 TI - Isolation of plasma membrane from tissue culture--L cells. PMID- 4138147 TI - Isolation of plasma membranes from intestinal brush borders. PMID- 4138149 TI - [A rational preparation of small mammal brains (albino rat) for the manufacture of serial sections]. PMID- 4138150 TI - [Treatment of kidney and upper urinary tract tumors]. PMID- 4138148 TI - Isolation of postsynaptic densities from rat brain. AB - Most synapses in the central nervous system exhibit a prominent electron-opaque specialization of the postsynaptic plasma membrane called the postsynaptic density (PSD). We have developed a procedure for the isolation of PSDs which is based on their buoyant density and their insolubility in N-lauroyl sarcosinate. Treatment of synaptic membranes with this detergent solubilizes most plasma membranes and detaches PSDs from the plasma membrane so that they can be purified on a density gradient. Isolated PSDs appear structurally intact and exhibit those properties which characterize them in tissue. The isolated PSDs are of the size, shape, and electron opacity of those seen in tissue; they stain with both ethanolic phosphotungstic acid and bismuth iodide-uranyl lead and the fraction contains cyclic 3',5'-phosphodiesterase activity. Quantitative electron microscope analysis of the PSD fraction gives an estimated purity of better than 85%. Inasmuch as the PSD is associated primarily with dendritic excitatory synapses, our PSD fraction represents the distinctive plasma membrane specialization of this specific synaptic type in isolation. PMID- 4138151 TI - [Treatment of postoperative urinary incontinence in man, using Kaufman's prosthesis. Preliminary report on 7 cases]. PMID- 4138152 TI - [Treatment of rhythm disorders with aprindine. Results in 86 patients]. PMID- 4138153 TI - [Treatment of septicopyemic forms of acute hematogenic osteomyelitis]. PMID- 4138155 TI - [Treatment of Basedow's disease by long-term administration of synthetic antithyroid drugs associated with small doses of I-131 prescribed without dosimetry. Apropos of 293 cases with a follow-up of 12 years]. PMID- 4138154 TI - [Treatment of tachycardias and arrhythmias. Studies using Visken]. PMID- 4138156 TI - Dermatological hypersensitivity to thiacetazone. PMID- 4138157 TI - Premature ventricular contraction. Part 1. Clinical significance. PMID- 4138159 TI - [Barbituric acids with indandione contained in the nucleus]. PMID- 4138158 TI - Inhibition of testosterone metabolism in the human prostate. PMID- 4138160 TI - A biblical case of hypothermia-resuscitation by rewarming (Elisha's method). PMID- 4138161 TI - Metabolic aspects of spontaneous rewarming in accidental hypothermia and hypothermic myxoedema. PMID- 4138162 TI - Metabolic aspects of the role of hyperthermia im mammalian cell inactivation and their possible relevance to cancer treatment. PMID- 4138164 TI - Cerebral blood flow and quantitative rheoencephalography. PMID- 4138163 TI - RNA-bound reverse transcriptase in Escherichia coli and in vitro synthesis of a complementary DNA. PMID- 4138165 TI - Urticaria. PMID- 4138166 TI - Thiacetazone induced Steven-Johnson syndrome: a case report. PMID- 4138167 TI - [Psychosomatic aspects of pruritus]. PMID- 4138168 TI - The claustrum and the transitional neo-paleocortical area of the hedgehog (Erinaceus europaeus). PMID- 4138169 TI - The combined use of high efficiency liquid and capillary gas chromatography for the determination of polycyclic aromatic hydrocarbons in automotive exhaust condensates and other hydrocarbon mixtures. PMID- 4138170 TI - New concepts and developments in applied diagnostic virology. PMID- 4138171 TI - [Edocrinal study of uterine fibromyoma]. PMID- 4138172 TI - Endocrine-like cells in rat stomach: effects of 6-hydroxydopa on amine stores and amino acid decarboxylase activities. A chemical, fluorescence histochemical and electron microscopic study. PMID- 4138173 TI - Effect of buffer storage on fine structure and catalase cytochemistry of peroxisomes. PMID- 4138174 TI - Effect of maturation and aging on the rate of fast axoplasmic transport in mammalian nerve. PMID- 4138175 TI - Effect of prolonged beta-receptor blockade on dry weight and electrophysiological responses of rabbit hearts. PMID- 4138176 TI - Effect of severe, chronic illness on thyroid function. PMID- 4138178 TI - Detection of "C" type-oncornaviruses of cattle with spontaneous and with experimentally induced lymphatic leukemia. PMID- 4138179 TI - Detection of a specific antigen of amyloid fibrils in mice. PMID- 4138180 TI - [Reaction of anti-A-hemagglutinin from Helix pomatia with algae (Chlorella pyrenoidosa) and demonstration of heterophilic agglutinins against algae in human sera]. PMID- 4138181 TI - Detection of human reagins with rat peritoneal mast cells by histamine release. PMID- 4138182 TI - Rejection of tumor transplants after incubation in alkylated diffusion chambers. PMID- 4138183 TI - Infections caused by Pseudomonas species in patients with burns and in other surgical patients. PMID- 4138184 TI - Selective histochemical staining of cartilage matrix by Rivanol. PMID- 4138185 TI - Galactose neurotoxicity in chicks: effects on fast axoplasmic transport. PMID- 4138186 TI - [Electron microscopic investigations of juvenile angio-fibroma of the naso pharynx (author's transl)]. PMID- 4138187 TI - Effects of freezing in the presence of beta-mercaptoethanol on the antigenicity of peanut proteins. PMID- 4138188 TI - Effects of repetitive stimulation on membrane potentials and twitch in human and rat intercostal muscle fibres. PMID- 4138189 TI - Aspects of the Odland bodies in the synthesis of keratohyalin. PMID- 4138190 TI - Effects of 25-hydroxycholecalciferol on urinary electrolyte excretion in hypophosphataemic rickets. PMID- 4138191 TI - Structural and eletrophysiological properties of nymphal and adult insect medial neurosecretory cells: an in vitro analysis. PMID- 4138192 TI - Structural proteins associated with ribosomal cistrons in Xenopus laevis chromosomes. PMID- 4138193 TI - Structure antigenicity relationships of glucagon and related peptides. PMID- 4138195 TI - Pediculosis today. PMID- 4138194 TI - Structure of infectious bursal disease virus. AB - Infectious bursal disease virus of chickens was purified, and its structure was examined by the negative-staining technique in the electron microscope. The buoyant density of infectious bursal disease virus in CsCl was found to be 1.34 g/cm(3). The morphological details suggest that the capsid of the virion consists of a single layer of 32 capsomeres arranged in 5:3:2 symmetry. The virion measured about 55 nm in diameter and had no envelope. PMID- 4138196 TI - The cytochemical bioassay of ACTH. PMID- 4138197 TI - Solid phase radioimmunoassay for identification of Herpesvirus hominis types 1 and 2 from clinical materials. AB - A solid phase radioimmunoassay (RIA) was developed for typing Herpesvirus hominis (HVH) strains isolated from clinical materials, and it also proved to be applicable to the direct detection and typing of HVH antigen in human and animal brain tissue. The procedure utilized virus-infected human fetal diploid cells or brain tissue smears in the bottom of 1-dram glass vials, antigen was detected through the use of intermediate HVH antisera produced in rabbits or hamsters and cross-absorbed with the HVH heterotype, and (125)I-labeled anti-species (rabbit or hamster) globulins produced in goats were used for detection of immune complexes. The cross-absorbed HVH antisera could be used at high dilutions in the RIA test, and they reacted with marked type-specificity in the RIA system. Specificity of the test was also improved by determining and using optimal concentrations of intermediate sera and of (125)I-labeled anti-species globulins. Results of typing HVH isolates by the RIA procedure agreed in all instances with those obtained by direct fluorescent antibody staining with cross-absorbed conjugates. The RIA procedure was effective and more sensitive than direct fluorescent antibody for demonstrating and typing HVH antigen directly in smears of infected human brain tissue. PMID- 4138198 TI - T and B lymphocytes in systemic lupus erythematosus. PMID- 4138199 TI - Blood-group serology of fractions obtained from the human erythrocyte membrane. PMID- 4138200 TI - Incidence and meaning of the "e" determinant among hepatitis-B-antigen positive patients with acute and chronic liver diseases. Report from the Copenhagen Hepatitis Acuta Programme. PMID- 4138201 TI - Acrodermatitis enteropathica. Report of a case healed with zinc therapy. PMID- 4138202 TI - The development of secondary epileptic discharges in the rhesus monkey after commissure section. PMID- 4138203 TI - [Studies of enzootic bronchopneumonia in calves on consolidated farms. I. The effect of lactoplasmin, gamma-globulin and a tissue preparation on the course of Joffe's test in newborn and growing calves]. PMID- 4138204 TI - [Studies of organochlorine pesticide residues in animal fatty tissues]. PMID- 4138205 TI - [Studies on a skin manifestation in a case of Whipple's disease]. PMID- 4138206 TI - [Studies on the conidial differentiation of "Neurospora crassa". V. Ultrastructure of the macroconidiogenous sequence (author's transl)]. PMID- 4138207 TI - [Studies on Bleomycin]. PMID- 4138208 TI - A modified rotary L.E.-cell method for enhancing L.E.-cell production. PMID- 4138209 TI - Hereditary transcobalamin II deficiency: clinical findings in a new family. PMID- 4138210 TI - Dihydrostreptomycin accumulation in E. coli. PMID- 4138211 TI - New drugs of 1973. PMID- 4138212 TI - [Study on anti-Leishmania Donovani antibodies in a sample of animal serums]. PMID- 4138213 TI - [Case demonstration: Papillomatosis cutis carcinoides (Gottron) in epidermolysis bullosa dystrophica]. PMID- 4138214 TI - Acute epidermal necrolysis (Lyell syndrome) induced by thiacetazone. PMID- 4138215 TI - [Case of acute myocarditis and hepatitis after combined administration of antitetanus serum, gamma globulin and antirabies vaccine]. PMID- 4138216 TI - [Role of axoplasmic transport in synaptic structure and function]. PMID- 4138217 TI - Acute phase reaction following intravenous administration of streptokinase. PMID- 4138218 TI - Three ways of using immunology to investigate the cell surface: cocapping, helper determinants and immunogenicity. PMID- 4138219 TI - Stage D prostatic carcinoma. Survival rate in relapsed patients following new forms of palliation. PMID- 4138220 TI - Three-dimensional ultrastructure of the crayfish neuromuscular apparatus. AB - The synapse-bearing nerve terminals of the opener muscle of the crayfish Procambarus were reconstructed using electron micrographs of regions which had been serially sectioned. The branching patterns of the terminals of excitatory and inhibitory axons and the locations and sizes of neuromuscular and axo-axonal synapses were studied. Excitatory and inhibitory synapses could be distinguished not only on the basis of differences in synaptic vesicles, but also by a difference in density of pre- and postsynaptic membranes. Synapses of both axons usually had one or more sharply localized presynaptic "dense bodies" around which synaptic vesicles appeared to cluster. Some synapses did not have the dense bodies. These structures may be involved in the physiological activity of the synapse. Excitatory axon terminals had more synapses, and a larger percentage of terminal surface area devoted to synaptic contacts, than inhibitory axon terminals. However, the largest synapses of the inhibitory axon exceeded in surface area those of the excitatory axon. Both axons had many side branches coming from the main terminal; often, the side branches were joined to the main terminal by narrow necks. A greater percentage of surface area was devoted to synapses in side branches than in the main terminal. Only a small fraction of total surface area was devoted to axo-axonal synapses, but these were often located at narrow necks or constrictions of the excitatory axon. This arrangement would result in effective blockage of spike invasion of regions of the terminal distal to the synapse, and would allow relatively few synapses to exert a powerful effect on transmitter release from the excitatory axon. A hypothesis to account for the development of the neuromuscular apparatus is presented, in which it is suggested that production of new synapses is more important than enlargement of old ones as a mechanism for allowing the axon to adjust transmitter output to the functional needs of the muscle. PMID- 4138221 TI - Increase of T lymphocytes in the spleen in Hodgkin's disease. PMID- 4138222 TI - [Telecobaltotherapy in the treatment of corpus uteri cancer (author's transl)]. PMID- 4138223 TI - [Effect of bishydroxycoumarin on the intestinal absorption of some sugars]. PMID- 4138224 TI - [Effect of certain biological and physical factors on the bactericidal and protective reactions of the body. I. The effect of a tissue emulsion, vitamin A and nonspecific gamma-globulin on the blood clearance in rabbits]. PMID- 4138225 TI - [Effect of motor transport noise and pollution of the air with gases on the body]. PMID- 4138226 TI - [Effect of radical treatment of Basedow's disease on the ocular symptoms]. PMID- 4138227 TI - [Detection of ABO antigens in stained histological sections by absorption-elution and mixed agglutination reactions. A preliminary report]. PMID- 4138228 TI - Proceedings: Changes in response to chemotherapeutic agents during ther life history of monolayer cultures of a mouse tumour cell line. PMID- 4138229 TI - Proceedings: Histamine output from the rat gastric mucosa during stimulation and inhibition of acid secretion. PMID- 4138230 TI - Proceedings: The surface ultrastructure of exfoliated cervical cells. PMID- 4138231 TI - The effect of betamethasone valerate on seborrhoeic dermatitis of the scalp. A clinical, histopathological cell kinetic study. PMID- 4138232 TI - The effect of cationic triphenylmethane dye (crystal violet) on rabbit granulation tissue. Oxygen consumption and RNA and protein synthesis in tissue slices. PMID- 4138233 TI - The effect of electric stimulation on the axoplasmic transport of newly synthetized neuronal proteins. PMID- 4138234 TI - The effect of erythrocyte antigen structure on requirement for T cells. PMID- 4138235 TI - The effect of pseudopregnancy, induced with a combination of mestranol and chlormadinone acetate, on carbohydrate metabolism and nonesterified fatty acid level. PMID- 4138236 TI - [Panel discussion: Evaluation of the antiarrhythmic drugs and current problems associated with their use in clinical practice (author's transl)]. PMID- 4138237 TI - Samuel Norman Lytle. PMID- 4138238 TI - A preliminary report of a rapid method for the demonstration of abnormal gammaglobulin levels in bovine whole blood. PMID- 4138240 TI - System and crisis: a psychosomatic model of human development. PMID- 4138239 TI - Subcellular fractionation of rat liver. PMID- 4138241 TI - Schlemm's canal and scleral spur in normal and glaucomatous eyes. PMID- 4138242 TI - [Attempts at influencing phagocytosis in calves by means of certain biologically active preparations]. PMID- 4138243 TI - Evidence for a rapid phase of axoplasmic transport at early stages in the development of the visual system of the chick and frog. PMID- 4138244 TI - Evidence for inapparent rabies infection. PMID- 4138245 TI - Presenile dementia: further experience with an anticoagulant-psychotherapy regimen. PMID- 4138246 TI - Screening for disease: Definitions and criteria. PMID- 4138247 TI - Current activites of the APS Education Committee. PMID- 4138248 TI - Prevention of deep-vein thrombosis by low-dose heparin in patients undergoing total hip replacement. PMID- 4138249 TI - [Sleep in the kangaroo rat (Potorous apicalis). A study in the adult and in the young one month before final leaving of the pouch. Effects of weaning]. PMID- 4138250 TI - Letter: L.A.T.S. and Graves' disease. PMID- 4138251 TI - Letter: "Rotavirus" in stored specimens of faecal extracts. PMID- 4138252 TI - Letter: "Self" versus "non-self": in situ proteins. PMID- 4138253 TI - Letter: A radioimmunoassay for serum-alpha-fetoprotein based on commercial antisera. PMID- 4138254 TI - Letter: Acetylcholine poisoning and sympathetic overactivity in tetanus. PMID- 4138255 TI - Letter: Acid-base diagrams. PMID- 4138256 TI - Letter: Action of cysteamine in paracetamol poisoning. PMID- 4138257 TI - Letter: Activation or unblocking of T lymphocytes. PMID- 4138258 TI - Letter: Acupuncture for drug addiction. PMID- 4138259 TI - Letter: Acute arthralgia after high-dose intravenous methylprednisolone. PMID- 4138260 TI - Letter: Aetiology of Crohn's disease. PMID- 4138261 TI - Letter: Ampicillin-resistant haemophilus influenzae. PMID- 4138262 TI - Letter: An evolutionary theory of premenstrual tension. PMID- 4138263 TI - Letter: Anatomy of hepatic duct. PMID- 4138264 TI - Letter: Angina pectoris with normal coronary arteries. PMID- 4138265 TI - Letter: Angina pectoris with normal coronary arteries. PMID- 4138266 TI - Letter: Antigenicity of "monocomponent" insulins. PMID- 4138267 TI - Letter: Arachidonic acid and platelet aggregation. PMID- 4138268 TI - Letter: Ascorbic acid in treatment of pressure-sores. PMID- 4138269 TI - Letter: Atypical lymphocytes in infectious mononucleosis. PMID- 4138270 TI - Letter: B.A.L. in paracetamol poisoning. PMID- 4138271 TI - Letter: Basic encephalitogen and unresponsive multiple sclerosis. PMID- 4138272 TI - Letter: Beclomethasone aerosol in chronic bronchial asthma. PMID- 4138273 TI - Letter: Beta-adrenergic blockade in the treatment of M.A.O.I. self-poisoning. PMID- 4138274 TI - Letter: Blue eyedrops. PMID- 4138275 TI - Letter: Candicidin for benign prostatic hypertrophy. PMID- 4138276 TI - Letter: Care of the critically ill. PMID- 4138277 TI - Letter: Cellular immunity in minimal-lesion nephrosis. PMID- 4138278 TI - Letter: Changing pattern of antenatal diagnosis. PMID- 4138279 TI - Letter: Chlorpropamide in diabetic pregnancy. PMID- 4138280 TI - Letter: Chondroitinsulphaturia with alpha-L-iduronidase deficiency. PMID- 4138281 TI - Letter: Classification of non-Hodgkin's lymphomas. PMID- 4138282 TI - Letter: Clinical trials with vitamin C. PMID- 4138283 TI - Letter: Comparison between free thyroxine index and effective thyroxine ratio. PMID- 4138284 TI - Letter: Computers in intensive care. PMID- 4138285 TI - Letter: Controlled-environment treatment for postoperative management of wounds. PMID- 4138286 TI - Letter: Cot deaths. PMID- 4138287 TI - Letter: Cot deaths. PMID- 4138288 TI - Letter: Countercurrent immunoelectrophoresis for rapid diagnosis of dengue haemorrhagic fever. PMID- 4138289 TI - Letter: Cyclic A.M.P. and morphine analgesia. PMID- 4138290 TI - Letter: Defibrination and head injury. PMID- 4138291 TI - Letter: Diabetes in pregnancy. PMID- 4138292 TI - Letter: Diet and cardiovascular disease. PMID- 4138294 TI - Letter: Down with parameters. PMID- 4138293 TI - Letter: Dopamine-beta-hydroxylase and sympatho-adrenal activity. PMID- 4138295 TI - Letter: E-aminocaproic acid and subarachnoid haemorrhage. PMID- 4138296 TI - Letter: E-rosette test. PMID- 4138297 TI - Letter: Efficacy of influenza vaccines. PMID- 4138298 TI - Letter: Endoscopy in gastrointestinal bleeding. PMID- 4138299 TI - Letter: Environmental stress and thyrotoxicosis. PMID- 4138300 TI - Letter: Epsilon-aminocaproic acid and subarachnoid haemorrhage.?211. PMID- 4138301 TI - Letter: Estimation of blood-carboxyhaemoglobin. PMID- 4138303 TI - Letter: Evitable injuries. PMID- 4138302 TI - Letter: Evans Blue counterstain for immunofluorescence. PMID- 4138304 TI - Letter: Exercise and myocardial infarction. PMID- 4138305 TI - Letter: Factor VIII in von Willebrand's disease. PMID- 4138306 TI - Letter: Failure of "adequate" penicillin therapy to prevent bacterial endocarditis after tooth extraction. PMID- 4138307 TI - Letter: False-positives. PMID- 4138308 TI - Letter: Fluid balance after major surgery in chronic renal failure. PMID- 4138309 TI - LEtter: Food antibodies and myocardial infarction. PMID- 4138310 TI - Letter: Food antibodies and myocardial infarction. PMID- 4138311 TI - Letter: Food antibodies and myocardial infarction. PMID- 4138312 TI - Letter: Glycosuria and hyperglycaemia after kidney transplantation. PMID- 4138313 TI - Letter: Granular dystrophy of the cornea. PMID- 4138314 TI - Letter: Haloperidol, thyrotoxicosis, and neurotoxicity. PMID- 4138315 TI - Letter: Health services in Chile. PMID- 4138316 TI - Letter: Hepatitis-B antigen in vaginal secretions. PMID- 4138317 TI - Letter: Hepatitis-B surface antigen in breast milk. PMID- 4138318 TI - Letter: High avidity antibody in long-term survivors of acute leukaemia. PMID- 4138319 TI - Letter: Histological changes following chemical face peeling. PMID- 4138320 TI - Letter: Homocarnosinosis: a new metabolic disorder associated with spasticity and mental retardation. PMID- 4138321 TI - Letter: Hurler's syndrome with clear corneas. PMID- 4138322 TI - Letter: Hypothermic total body-washout with survival in Reye's syndrome. PMID- 4138323 TI - Letter: Immunodeficiency in the cerebro-hepato-renal syndrome of Zellweger. PMID- 4138324 TI - Letter: Immunohistochemical localization of complement in intestinal mucosa. PMID- 4138325 TI - Letter: In-vitro detection of hypersensitivity to antituberculous drugs. PMID- 4138326 TI - Letter: Increase of premalignant cervical lesions in teenagers. PMID- 4138328 TI - Letter: Intellectual function after head injury. PMID- 4138327 TI - Letter: Insulin suppression. PMID- 4138329 TI - Letter: Intestinal potential difference during glucose absorption. PMID- 4138330 TI - Letter: Intrauterine device, prostaglandins and copper. PMID- 4138331 TI - Letter: Jack becomes master. PMID- 4138332 TI - Letter: Jack becomes master? PMID- 4138333 TI - Letter: Late urinary-tract infection after renal transplantation. PMID- 4138334 TI - Letter: Lithium and magnesium-dependent enzymes. PMID- 4138335 TI - Letter: Low carbon-monoxide cigarettes. PMID- 4138336 TI - Letter: Low-dose heparin and stress ulceration. PMID- 4138337 TI - Letter: Lower-motor-neurone disease in mice and amyotrophic lateral sclerosis in man. PMID- 4138338 TI - Letter: Lymphocyte function and iron-deficiency anaemia. PMID- 4138339 TI - Letter: Lymphocyte-membrane adenosine triphosphatase. PMID- 4138340 TI - Letter: Lymphocytes in common variable (adult "acquired") hypogammaglobulinaemia. PMID- 4138341 TI - Letter: Mechanism of diarrhoea in cholera. PMID- 4138342 TI - Letter: Mechanism of lactic acidosis. PMID- 4138343 TI - Letter: Membranous nephropathy and hepatitis-B antigen. PMID- 4138344 TI - Letter: Meningococcal infection in London. PMID- 4138345 TI - Letter: Minocycline: possible vestibular side-effects. PMID- 4138346 TI - Letter: Minocycline: possible vestibular side-effects. PMID- 4138347 TI - Letter: Missing sex chromosomes and translocations in acute leukaemia. PMID- 4138348 TI - Letter: Monoamine-oxidase and migraine. PMID- 4138350 TI - Letter: Multiple sclerosis and diet. PMID- 4138349 TI - Letter: Multiple sclerosis and diet. PMID- 4138351 TI - Letter: New concepts in medical education. PMID- 4138352 TI - Letter: Non-specific enhancement of glomerular filtration by corticosteroids. PMID- 4138353 TI - Letter: Non-treatment of hypertension. PMID- 4138354 TI - Letter: Non-treatment of hypertension. PMID- 4138355 TI - Letter: Nuclear projections in tumour cells. PMID- 4138356 TI - Letter: Oral contraceptives and health. PMID- 4138357 TI - Letter: Oral sodium cromoglycate in gastrointestinal allergy. PMID- 4138358 TI - Letter: Origin of alpha-fetoprotein. PMID- 4138359 TI - Letter: Origin of malignant lymphomas. PMID- 4138360 TI - Letter: Oxolinic acid in urinary infections. PMID- 4138361 TI - Letter: Oxygen-modified collagen and bone necrosis in divers. PMID- 4138362 TI - Letter: Pathogenesis of coeliac sprue. PMID- 4138363 TI - Letter: Peak-flow meter versus peak-flow gauge. PMID- 4138364 TI - Letter: Penicillamine and zinc. PMID- 4138365 TI - Letter: Phenobarbitone and liver tumours. PMID- 4138366 TI - Letter: Phenolphthalein in "aspirin". PMID- 4138368 TI - Letter: Plasma-digoxin concentrations after an intravenous loading dose. PMID- 4138369 TI - Letter: Plasma-prolactin in breast cancer. PMID- 4138367 TI - Letter: Pitfalls in hepatitis A? PMID- 4138370 TI - Letter: Portacaval shunt in familial hypercholesterolaemia. PMID- 4138371 TI - Letter: Possible role of prostaglandins in idiopathic postural hypotension. PMID- 4138372 TI - Letter: Postoperative pulmonary embolism. PMID- 4138373 TI - Letter: Predictive value of laboratory tests. PMID- 4138374 TI - Letter: Prevention of bacterial endocarditis after tooth extraction. PMID- 4138375 TI - Letter: Proportional mortality among vinyl-chloride workers. PMID- 4138376 TI - Letter: Protein requirement. PMID- 4138377 TI - Letter: Protein requirement. PMID- 4138378 TI - Letter: Rapid diagnosis of Down's syndrome. PMID- 4138379 TI - Letter: Rauwolfia derivatives and breast cancer. PMID- 4138380 TI - Letter: Rauwolfia derivatives and breast cancer. PMID- 4138381 TI - Letter: Rauwolfia derivatives and breast cancer. PMID- 4138382 TI - Letter: Renal abnormality of essential hypertension. PMID- 4138383 TI - Letter: Reserpine, prolactin, allergy, and breast cancer. PMID- 4138384 TI - Letter: Role of adrenergic nerves in ovulation and ovum transport. PMID- 4138385 TI - Letter: Satellite staining of human chromosomes. PMID- 4138386 TI - Letter: Scanning electron microscopy in assessment of protein-calorie malnutrition. PMID- 4138388 TI - Letter: Seasonal variation of histological osteomalacia in femoral-neck fractures. PMID- 4138387 TI - Letter: Scanning electron microscopy of hairy cells in hairy-cell leukaemia. PMID- 4138389 TI - Letter: Serum-creatine-kinase levels in carriers of Becker muscular dystrophy. PMID- 4138390 TI - Letter: Serum-muramidase in leukaemic reticuloendotheliosis. PMID- 4138391 TI - Letter: Skin prolyl hydroxylase. PMID- 4138392 TI - Letter: Skin wrinkling in cystic fibrosis. PMID- 4138393 TI - Letter: Sleep and ventricular premature beats. PMID- 4138394 TI - Letter: Smoking and lung cancer. PMID- 4138395 TI - Letter: Smoking and the heart. PMID- 4138396 TI - Letter: Sperm-induced lymphocyte transformation. PMID- 4138397 TI - Letter: Spinal-fluid lysozyme in diagnosis of central-nervous-system tumours. PMID- 4138398 TI - Letter: Spread of hepatitis in dialysis units. PMID- 4138399 TI - Letter: Starch emboli in transplanted kidneys. PMID- 4138400 TI - Letter: Subacute sclerosing panencephalitis in the Middle East. PMID- 4138401 TI - Letter: Subcutaneous heparin. PMID- 4138402 TI - Letter: SI units. PMID- 4138403 TI - Letter: T lymphocytes and immunoglobulins in the aged. PMID- 4138404 TI - Letter: Termination of first-trimester pregnancies. PMID- 4138405 TI - Letter: The benzodiazepine bonanza. PMID- 4138407 TI - Letter: The nurse in the community. PMID- 4138406 TI - Letter: The great protein fiasco. PMID- 4138408 TI - Letter: The pigeon as reservoir for cryptococcus neoformans. PMID- 4138409 TI - Letter: The role of lay visitors in hospitals. PMID- 4138410 TI - Letter: The spleen in Hodgkin's disease. PMID- 4138411 TI - Letter: The T lymphocyte and hepatitis. PMID- 4138412 TI - Letter: Toxic substances, synergism, and drinking-water. PMID- 4138413 TI - Letter: Toxicity of dimethylformamide. PMID- 4138414 TI - Letter: Training of nurses. PMID- 4138415 TI - Letter: Transient bacteraemia complicating peroral jejunal biopsy. PMID- 4138416 TI - Letter: Treatment of hypertension. PMID- 4138417 TI - Letter: Treatment of lung cancer. PMID- 4138418 TI - Letter: Treatment of lung cancer. PMID- 4138419 TI - Letter: Treatment of thallium poisoning. PMID- 4138420 TI - Letter: Tryptophan in depression. PMID- 4138421 TI - Letter: Tryptophan in depression. PMID- 4138422 TI - Letter: Tryptophan in depression. PMID- 4138423 TI - Letter: Twinning and neural-tube defects. PMID- 4138424 TI - Letter: Unexplained tetanic spasms. PMID- 4138425 TI - Letter: Virus-like particles in hepatitis-A-positive faecal extracts. PMID- 4138426 TI - Letter: Vitamin-B12 deficiency. PMID- 4138427 TI - Letter: Wart-virus antibodies and multiple sclerosis. PMID- 4138429 TI - Letter: Why admit abortion patients? PMID- 4138428 TI - Letter: White-cell glutathione reductase in cystic fibrosis. PMID- 4138430 TI - Letter: Yersinia enterocolitica infection and thyroid disorders. PMID- 4138432 TI - Differences in cell surface characteristics between glucocorticoid-sensitive and resistant mouse lymphomas. PMID- 4138431 TI - Temperature-sensitive mutants of murine leukemia virus. IV. Further physiological characterization and evidence for genetic recombination. AB - Several temperature-sensitive mutants of the Rauscher strain of murine leukemia virus representing three distinct physiological groups have been further characterized. Genetic recombination between different pairs of these mutants has been demonstrated. Several representative genetic recombinants were isolated and shown to replicate equally well at the permissive (31 C) and nonpermissive (38 C) temperatures and to have serological characteristics of the wild-type parental virus. Alternative models for the mechanisms involved in recombination between type C RNA viruses are discussed. PMID- 4138433 TI - Differential renal protein clearance in toxaemia of pregnancy. PMID- 4138434 TI - Differential susceptibility of mouse trophoblast and embryonic tissue to immune cell lysis. PMID- 4138435 TI - [Experimental porphyria model with hexachlorocyclohexane]. PMID- 4138436 TI - [Experimental study of L 5818 Labaz used as a vasocontrictor in nasal instillation]. PMID- 4138437 TI - Properties and reaction mechanism of DT diaphorase from rat liver. PMID- 4138438 TI - Properties of an antigenic polysaccharide from Corynebacterium parvum. AB - Corynebacterium parvum strain 10390 is an antitumor agent and stimulant of the reticuloendothelial system and produces a soluble antigen towards the end of its growth cycle. This material, which is a cell wall component and can also be released from the organism by acid or alkaline hydrolysis, has been purified. It is an acidic polysaccharide of molecular weight 100,000 to 150,000 and contains galactose, glucose, fucose, N-acetylgalactosamine, N-acetylglucosamine, uronic acids, sialic acids, and a small proportion of amino acids. The antigen gives a precipitin reaction with antisera raised against the whole organism and also binds to animal cells. The antigenic determinants are extremely resistant to oxidation, reduction, and enzymatic and chemical hydrolysis, but the single cell binding site is destroyed by alkali and also by Helix pomatia digestive juice, alginase, and neuraminidase without substantially affecting the molecular weight. This site is inaccessible until the molecule is released from the cell surface. The possibility that the soluble antigen is the biologically active fraction of C. parvum is discussed. PMID- 4138439 TI - Properties of histocompatibility (HL-A) determinants. 3. The independent preciptation and epitope valence of soluble HL-A determinants. PMID- 4138440 TI - Properties of intracytoplasmic A particles isolated from oncornavirus-producing human cells. AB - A particles with the diameter of 70 to 80 nm were isolated from the cytoplasm of HEp-2, HeLa, and AO cells producing oncornavirus of Mason-Pfizer-like type. Most of the A particles banded at 1.23 to 1.24 g/ml, whereas 3 to 10% banded at 1.29 g/ml in equilibrium sucrose gradients. They banded at 1.30 g/ml in CsCl gradients suggesting that they contained 8% RNA. Individual A particles sedimented at 200 to 250S in velocity sucrose gradients, but their significant part was found aggregated and sedimented at more than 300S. They were resistant to RNase digestion. A particles possessed polymerase activity which was preferentially activated by Mn(2+) rather than by Mg(2+), the RNA template being 60S RNA. Cross hybridization with two DNA products and immunoassay showed that A particles and Mason-Pfizer-like oncornavirus produced by the same cells contained neither homological RNA sequences nor common antigens, suggesting that A particles are not intracellular precursors of Mason-Pfizer-like oncornavirus but represent an independent oncornavirus. Hybridization of A particle RNA with excess of cellular DNA revealed about 20 proviral copies per HEp-2 cell genome and no proviral copies in human embryo and placenta cell genomes. PMID- 4138441 TI - Properties of ribosomes from Streptomyces erythreus and Streptomyces griseus. AB - Ribosomes from an erythromycin-producing strain, Streptomyces erythreus, lacked affinity for erythromycin and were also resistant to other macrolide antibiotics (leucomycin, spiramycin, and tylosin) and to lincomycin, whereas Streptomyces griseus B(3) ribosomes were susceptible to all of these antibiotics. PMID- 4138442 TI - Repression of enzymes of nitrogen catabolism by methylammonium and caesium chloride in strains of Aspergillus nidulans insensitive to ammonium repression. PMID- 4138443 TI - Expression of selected antigens on the surface of cultured neural cells. PMID- 4138444 TI - Diabetes mellitus death-rates in England and Wales 1920-70 and food supplies. PMID- 4138445 TI - Enuretic alarm trainer for night and day. PMID- 4138446 TI - Secretion of dihydrotestosterone by human prostate in benign prostatic hypertrophy. PMID- 4138447 TI - Excretion of penicillin G and dihydrostreptomycin from quarters of cows with experimentally induced staphylococcal mastitis. PMID- 4138448 TI - Society's misfits. The homeless alcoholic. PMID- 4138449 TI - The evidence for involvement of type C RNA tumor viruses in human acute leukemia. PMID- 4138451 TI - The eye and its disorders. 18. Squint. PMID- 4138452 TI - The eye and its disorders. 28. The retina. PMID- 4138453 TI - [Surface alterations of the epithelium of the hyperplastic pharyngeal tonsil. A scanning electron microscopic study (author's transl)]. PMID- 4138454 TI - The fate of patients after incomplete resection of bronchial carcinoma. PMID- 4138455 TI - Key features for the identification of 250 hospital isolates of Pseudomonas aeruginosa, with observation on their in vitro susceptibility to 10 antibiotics. PMID- 4138456 TI - 5. Effects on staining of the presence of various kinds of dye impurities. PMID- 4138457 TI - Purification of avian myeloblastosis virus DNA polymerase by affinity chromatography on polycytidylate-agarose. AB - Polycytidylic acid [poly(rC)] covalently linked to cyanogen bromide-activated agarose is an effective affinity matrix for the RNA-dependent DNA polymerase from avian myeloblastosis virus. Poly(rC)-agarose is capable of binding large quantities of avian myeloblastosis DNA polymerase, which is then eluted by using a linear KCl gradient of increasing concentration. The DNA polymerase isolated from crude, detergent-disrupted virions by a single pass through columns of poly(rC)-agarose appears nearly homogeneous (approximately 90% pure) as determined by sodium dodecyl sulfate-polyacrylamide disc gel electrophoresis. Complete recovery of input enzymatic activity was obtained. Results suggest that polyribonucleotide columns may provide a high-yield, rapid method for the purification of oncornaviral DNA polymerase. PMID- 4138458 TI - [Long term monitoring of the EEG in neurological-neurosurgical intensive care (author's transl)]. PMID- 4138459 TI - [Long-term effects of anti-thyroid agents in thyrotoxicosis (author's transl)]. PMID- 4138460 TI - Management of patients with primary immune deficiency syndromes. PMID- 4138461 TI - Antigen-initiated B lymphocyte differentiation. Kinetics and T lymphocyte dependence of the primary and secondary in vitro immune responses to the hapten 4 hydroxy-3-iodo-5-nitrophenylacetic acid presented on the carrier polymerised bacterial flagellin. PMID- 4138462 TI - Cytogenetic and linkage studies of a familial 15pplus variant. PMID- 4138464 TI - Antigenic relationships among strains of African swine fecre virus. PMID- 4138463 TI - Polygenic factors controlling drug response. PMID- 4138465 TI - [Congenital pain insensitivity syndrome associated with lymphatic proliferation and dysgammaglobulinemia]. PMID- 4138466 TI - Autogenous immunity to endogenous RNA tumor virus: differential reactivities of immunoglobulins M and G to virus envelope antigens. AB - The autogenous humoral immune response of mice to their endogenous leukemia virus has been examined in terms of the reactivities of individual classes of antibody present in normal B6C3F(1) serum. Whole serum and the immunoglobulin (Ig) M and IgG fractions of serum from animals of different age groups were compared by radioimmune precipitation assays and viral infectivity neutralization assays. Both IgM and IgG fractions were able to precipitate virus, although not as effectively as whole serum. Virus-specific antibody levels, as well as total antibody concentrations in whole serum, appeared to increase with age. Sodium dodecyl sulfate gel electrophoresis analysis was performed with immune precipitates obtained when whole serum or 19 or 7S fractions from animals of different age groups were reacted with disrupted virus. The 19S antibody fraction reacted with three antigenic determinants on the viral envelope. These antigens have apparent molecular weights of 17,000, 43,000, and 68,000. The last two appear to be glycoproteins and may correspond to the M(2) and M(1) antigens. In contrast, the 7S component reacted only with the 17,000-molecular-weight protein. Neutralization assays against BALB:virus-2, a xenotropic endogenous mouse type C virus, revealed that 19S and whole serum but not the 7S fraction possessed neutralizing activity. These findings indicate that there are differential reactivities of IgM and IgG antibodies in normal serum of B6C3F(1) mice, with respect to both recognition of viral envelope antigens and neutralization of endogenous MuLV. These results are consistent with the hypothesis that the autogenous humoral immune response is a systemic host function that may be important in the regulation of endogenous type C virus expression in vivo. PMID- 4138467 TI - Antigens of murine leukemia viruses. PMID- 4138469 TI - [Marginal notes on a Congress: treatment of stomach carcinoma. Studies of our cases]. PMID- 4138468 TI - Ontogeny of B-lymphocyte function. I. Restricted heterogeneity of the antibody response of B lymphocytes from neonatal and fetal mice. AB - The ontogeny of the ability of B lymphocytes to produce an antihapten response which is heterogeneous with respect to affinity for the antigenic determinant was studied in a cell transfer system. The heterogeneity of affinity of the immune response of lethally irradiated mice reconstituted with syngeneic, adult thymus cells and fetal or neonatal tissues as a source of B lymphocytes was studied. It was found that B cells from 17 day fetal liver or neonatal liver are highly restricted with respect to heterogeneity of affinity as compared with adult spleen or bone marrow. The B-cell population achieves an adult character with respect to heterogeneity of affinity by 2 wk of age. The peripheral lymphoid tissues (spleen) appear to mature in this respect more rapidly than do central lymphoid tissues (bone marrow). Spleens from 10-day old donors behave in an adult, heterogeneous manner while bone marrow from the same donors exhibit a marked restriction in heterogeneity of affinity. Germfree mice produce an immune response which is indistinguishable from conventionally reared adult animals with respect to heterogeneity of affinity. The earlier appearance of the ability to transfer a heterogeneous immune response in spleen as compared with bone marrow suggests that the increasing heterogeneity of the B-lymphocyte population which occurs between birth and 2 wk of age is the result of a differentiation event and not of a somatic mutation or recombination event. PMID- 4138470 TI - [Origins of blood transfusion. II]. PMID- 4138471 TI - I region-associated antigen system (Ia) of the mouse H-2 gene complex. Further definition of Ia secificities with restricted anti-Ia antisera. PMID- 4138472 TI - [Pregnancy after gestagen treatment during the first half of the cycle]. PMID- 4138473 TI - [Diagnosis and therapy of prostatic carcinoma]. PMID- 4138474 TI - [Diagnosis of chromosomal rearrangement by the banding staining method]. PMID- 4138475 TI - [Phagocytizing lymphocyte-like elements of the peripheral blood and prednisolone (experimental research)]. PMID- 4138476 TI - Na+-gradient-stimulated AIB transport in membrane vesicles from Ehrlich ascites cells. PMID- 4138477 TI - Integration of measles virus nucleic acid into the cell genome. PMID- 4138478 TI - Sjogren's syndrome in systemic lupus erythematosus. Clinical and subclinical manifestations. PMID- 4138479 TI - [Alpha-macroglobulins]. PMID- 4138480 TI - [Alpha-1-fetoprotein in umbilical cord sera and in newborn infants]. PMID- 4138481 TI - On the mechanism of action of glycoprotein from Candida albicans. PMID- 4138482 TI - On the relationship between the frequency of association and the nucleolar constriction of individual acrocentric chromosomes. PMID- 4138483 TI - The hemagglutinating and neuraminidase protein of a paramyxovirus: interaction with neuraminic acid in affinity chromatography. PMID- 4138484 TI - Biochemical suppression of tumor virus activity. PMID- 4138485 TI - Further studies on antigenic regions of bovine encephalitogenic protein with the lymph node cell transformation test in rabbits. PMID- 4138486 TI - Synthesis of viral-specific polypeptides in Mengo virus-infected L cells: evidence for asymmetric translation of the viral genome. PMID- 4138487 TI - Synthetic RNA-dependent DNA polymerase from calf thymus. PMID- 4138488 TI - Two high affinity estrogen binding proteins of different specificity in the immature rat uterus cytosol. PMID- 4138489 TI - [Technic of rapid detection of hemoglobinopathies]. PMID- 4138490 TI - [Methods for ultrathin sections, negative contrast and cleavage in research on the ultrastructural organization of model and cellular membranes]. PMID- 4138491 TI - Alcoholic brain damage: anticoagulant therapy. PMID- 4138492 TI - Morphologic observations on four cases of SED congenita. PMID- 4138493 TI - Morphological and functional maturation of human thymic epithelium in culture. PMID- 4138494 TI - Morphological contributions to monoamine pharmacology. PMID- 4138495 TI - Psychological death: an adaptive response to life-threatening illness. PMID- 4138496 TI - [Pathomorphological study of the vesico-ureteral reflux in patients with prostatic adenoma]. PMID- 4138497 TI - Synchronized combination bleomycin-methotrexat in regional chemotherapy of orofacial carcinomas. PMID- 4138498 TI - [Mushroom-like benign tumor of pericardium (author's transl)]. PMID- 4138499 TI - Prophylactic use of intravenous saline in patients with chronic renal failure undergoing major surgery. PMID- 4138500 TI - Prophylaxis of viral hepatitis. PMID- 4138501 TI - Plethysmographical and clinical observations on Bricanyl therapy in Raynaud's phenomenon. PMID- 4138502 TI - [Anti-arrhythmic efficacy of aprindine during the acute phase of myocardial infarct]. PMID- 4138503 TI - Carriage of Staphylococcus aureus and beta haemolytic streptococci in relation to race. PMID- 4138504 TI - Palliative cryosurgical treatment of the inoperable rectum carcinoma. PMID- 4138505 TI - Palliative intubation in the management of esophageal carcinoma. PMID- 4138506 TI - Possible detection of presensitization to donor alloantigens by immunofluorescence. PMID- 4138507 TI - [Optic nerve involvement with diffuse secondary meningeal blastomatosis (author's transl)]. PMID- 4138508 TI - Clinical evaluation of tumor scanning with 57Co-bleomycin. PMID- 4138509 TI - Atypical lymphocytes in acute infectious mononucleosis. Identification by multiple T and B lymphocyte markers. PMID- 4138510 TI - Clinical significance of hematospermia. PMID- 4138511 TI - Replication of oncornavirus-like particle in human breast carcinoma cell line, MCF-7. PMID- 4138512 TI - Clinico-pathologic conference. PMID- 4138513 TI - [Lipids distribution in compact bones revealed by Soudan black B (author's transl)]. PMID- 4138514 TI - Leslie Wakefield Hale. PMID- 4138516 TI - Studies on experimental itch induced by kallikrein and bradykinin. PMID- 4138517 TI - Studies on guinea pig skin cell cultures. 3. Minimum cell numbers for establishment. PMID- 4138515 TI - Studies of excitable membranes. I. Macromolecular specializations of the neuromuscular junction and the nonjunctional sarcolemma. AB - The neuromuscular junctions and nonjunctional sarcolemmas of mammalian skeletal muscle fibers were studied by conventional thin-section electron microscopy and freeze-fracture techniques. A modified acetylcholinesterase staining procedure that is compatible with light microscopy, conventional thin-section electron microscopy, and freeze-fracture techniques is described. Freeze-fracture replicas were utilized to visualize the internal macromolecular architecture of the nerve terminal membrane, the chemically excitable neuromuscular junction postsynaptic folds, and the electrically excitable nonjunctional sarcolemma. The nerve terminal membrane is characterized by two parallel rows of 100-110-A particles which may be associated with synpatic vesicle fusion and release. On the postsynpatic folds, irregular rows of densely packed 110-140-A particles were observed and evidence is assembled which indicates that these large transmembrane macromolecules may represent the morphological correlate for functional acetylcholine receptor activity in mammalian motor endplates. Differences in the size and distribution of particles in mammalian as compared with amphibian and fish postsynaptic junctional membranes are correlated with current biochemical and electron micrograph autoradiographic data. Orthogonal arrays of 60-A particles were observed in the split postsynaptic sarcolemmas of many diaphragm myofibers. On the basis of differences in the number and distribution of these "square" arrays within the sarcolemmas, two classes of fibers were identified in the diaphragm. Subsequent confirmation of the fiber types as fast- and slow twitch fibers (Ellisman et al. 1974. J. Cell Biol.63[2, Pt. 2]:93 a. [Abstr.]) may indicate a possible role for the square arrays in the electrogenic mechanism. Experiments in progress involving specific labeling techniques are expected to permit positive identification of many of these intriguing transmembrane macromolecules. PMID- 4138519 TI - Studies on mitochondrial structure and function in Physarum polycephalum. III. Electron microscopy of a large amount of DNA releases from a central body in mitochondria by trypsin digestion. PMID- 4138518 TI - Studies on human antiglobulins. Some properties of a "new" type. PMID- 4138520 TI - Studies on the depletion and accumulation of microvilli and changes in the tubulovesicular compartment of mouse parietal cells in relation to gastric acid secretion. AB - Gastric parietal cells in mice present a spectrum of microscopic appearances due mainly to variations in the abundance of the tubular and vesicular component of the cytoplasm and in the size and number of microvilli lining the intracellular canaliculi. Differences in the range of forms among parietal cells of fasting versus fed mice were not especially striking, but cells with very numerous tubules and vesicles were more common after fasting. However, in mice treated with drugs or hormones that induce acid secretion, parietal cells were more uniform in appearance. There was a marked reduction of these cytoplasmic membranes and a concomitant increase in both the number and size of microvilli. Measurements of acid secretion in control animals and in animals treated with acid secretagogues indicated hydrogen ion secretion contemporaneous with depletion of the cytoplasmic tubulovesicular membranes and with increase of the microvilli. In mice with inhibited acid secretion, parietal cells showed an accumulation of cytoplasmic tubules and vesicles and reduction in the numbers of microvilli. Stereological methods were used to quantitate 10 different parietal cell compartments. Tracer studies with lanthanum did not reveal continuity between the tubules and the plasma membrane. However, there were regions of close apposition between the tubulovesicular membranes and the cell membrane of the canaliculus, and instances where cytoplasmic tubules extended from the cell into the core of enlarged microvilli. PMID- 4138521 TI - Studies on the determinant group of the type specific antigen of Leptospira kremastos strain Kyoto. PMID- 4138522 TI - Studies on the effects of basic proteins on myelination in nerve tissue cultures. PMID- 4138523 TI - Studies on the motility of Plasmodium sporozoites. PMID- 4138524 TI - Studies on the role of calcium in the anaphylactic histamine release from isolated rat mast cells. PMID- 4138525 TI - Studies on the storage polysaccharides of the Coccidia Eimeria bovis and Eimeria stiedai. PMID- 4138526 TI - Studies with lectins on the surface carbohydrate structures of mycoplasma membranes. AB - The surface carbohydrate structures on the cell membranes of various mycoplasma species have been investigated by using lectins, which are sugar-specific proteins. Carbohydrate structures presumably bound to glycolipids, with both galactose and glucose units, were found to be exposed on the surface of Mycoplasma pneumoniae and its temperature-sensitive mutants, M. mycoides var. mycoides and capri, M. pulmonis, M. gallinarum, and M. gallisepticum. Lipid-bound glucose was found on M. neurolyticum. The possible relationship of the lipid bound surface carbohydrate groups to the known serological cross-reactions and lipid compositions of the various mycoplasma species is discussed. Intact Acholeplasma laidlawii and M. fermentans have no lectin-binding sites exposed on their surfaces; galactose groups were discovered only after Pronase digestion of the organisms, suggesting that their glycolipids are hidden under a protein layer. Neither intact nor Pronase-digested M. hominis reacted with the lectins; this is fully consistent with the lipid composition of this organism, which contains glycolipids. The lectins from Vicia cracca and Phaseolus vulgaris, which react with N-acetyl-galactosamine groups, agglutinated M. gallinarum, M. gallisepticum, M. mycoides var. capri, and M. pulmonis. The agglutinability was lost after Pronase treatment, indicating that the corresponding carbohydrates are presumably protein bound. They may be correlated with the extracellular structures observed by electron microscopy of both sectioned and negatively stained mycoplasma species. PMID- 4138527 TI - Specificity and cross-reactivity of antisynaptosome antibodies. PMID- 4138528 TI - Preliminary experience in the treatment of cardiac arrhythmias with aprindine. PMID- 4138530 TI - [A simple and effective method for avoiding unspecified staining in immunohistology]. PMID- 4138529 TI - The immunohistopathology of glomerular antigens. The glomerular basement membrane, collagen, and actomyosin antigens in normal and diseased kidneys. AB - The immunofluorescent localization of antisera to human glomerular basement membrane (GBM), collagen, and smooth muscle actomyosin was examined in 15 specimens of normal renal tissue and 98 specimens from patients with renal disease. The anti-GBM and anticollagen antisera normally localize to GBM, while antiactomyosin localizes to the mesangium. Diabetic nephropathy revealed a striking expansion of mesangial material reacting with antiactomyosin. In contrast, the expanded mesangium in membranoproliferative glomerulonephritis did not react with antiactomyosin, and the GBM localization of anti-GBM and anticollagen sera was similarly lost. The thickened GBM in diabetes mellitus and membranous nephropathy reacted with anti-GBM and anticollagen, but with accentuation of staining on the inner aspect of the GBM. In proliferative glomerulonephritis there was a moderate increase in the distribution of actomyosin. Glomerular sclerosis and hyalinization in all diseases studied was accompanied by a loss of immunofluorescent staining for all glomerular antigens, including collagen. PMID- 4138531 TI - [Perinatal hemolytic disease due to Rh incompatibility--a real social calamity. Interview granted to Minerva Ginecologica by Prof. Franco Gasparri]. PMID- 4138533 TI - Combined treatment of malignant tumor with irradiation and bleomycin. PMID- 4138532 TI - Uridine monophosphate kinase: A new genetic polymorphism with possible clinical implications. PMID- 4138534 TI - The influence of paraproteinaemia on the technicon automated platelet counter. AB - In five patients whose serum contained a paraprotein it has been shown that platelet counts obtained using the Technicon AutoCounter are much too high. In two patients with IgG gammopathy the error is caused by some factor in the red cells lysed by the diluent solution 2M urea. In three patients with IgM gammopathy spurious platelet counts were produced by platelet-poor plasma when diluted with 2M urea. It is recommended that at the present time no patient known to have a paraprotein should have platelet counts performed on the AutoCounter. PMID- 4138535 TI - The influence of portosystemic shunt operation on immunoglobulins and Escherichia coli antibodies in patients with cirrhosis of the liver. PMID- 4138536 TI - Smoking and the heart. The basis for action. PMID- 4138537 TI - Binding of rifampicin by human plasma proteins. PMID- 4138538 TI - Binding of secretory component to dimers of immunoglobulin A in vitro. A model for the interactions of the two moieties in secretory immunoglobulin A. PMID- 4138539 TI - Binding of soluble immune complexes to human lymphoblastoid cells. II. Use of Raji cells to detect circulating immune complexes in animal and human sera. AB - Cells from a human lymphoblastoid cell line (Raji), with B-cell characteristics, and having receptors for human IgG Fc, C3b, and C3d, were used in an immunofluorescence test as in vitro detectors of immune complexes in animal and human sera. By this test, as little as 200-300 ng aggregated human gamma globulin or immune complexes per ml serum could be detected. The receptors for IgG Fc on the Raji cells were shown to be inefficient in detecting aggregated human gamma globulin and binding of aggregates to these receptors was inhibited by physiologic concentrations of 7S human IgG. Enhancement of aggregated human gamma globulin binding and binding of immune complexes formed in vitro to Raji cells was observed when the receptors for complement on these cells were used. By using the receptors for complement on Raji cells, circulating immune complexes were detected in rabbits with acute serum sickness, in mice with acute lymphocytic choriomeningitis virus infection, and in humans with immune complex type glomerulonephritis. The Raji cell test may be useful in detecting complement fixing immune complexes in different disease states, in monitoring circulating complexes in patients with immune complex diseases and in identifying the antigen(s) responsible for the induction of pathogenic immune complexes in humans and animals. PMID- 4138540 TI - [Firing patterns of single motor units in the early stage of demyelinating neuropathy (author's transl)]. PMID- 4138541 TI - New inhibitor of reagin-mediated anaphylaxis. PMID- 4138542 TI - Carcinoma of the corpus and cervix--some thoughts about diagnosis and treatment. PMID- 4138543 TI - EEG instrumentation standards: report of the Committee on EEG Instrumentation Standards of the International Federation of Societies for Electroencephalography and Clinical Neurophysiology. PMID- 4138544 TI - The interaction of cationic liposomes containing entrapped horseradish peroxidase with cells in culture. AB - Cationic liposomes composed of sphingomyelin, cholesterol, and stearylamine were prepared with horseradish peroxidase trapped inside. Stable particles were formed in which 10-12% of the enzymic activity appeared to be located at, or near, the outer surface of the liposome. Adsorption and uptake of liposomes by HeLa cells were followed cytochemically by electron microscopy and quantitated by enzyme assay and by the distribution and fate of particles labeled with [(14)C]cholesterol and [(125)I]horseradish peroxidase. The particles were adsorbed by HeLa cells at least 300 times as efficiently as was free horseradish peroxidase. Many of the particles remained at the cell surface, but numerous membrane-bound cytoplasmic inclusions were observed to contain peroxidase staining material. In addition, many areas of the cell membrane gave a positive staining reaction. It was concluded that many particles (presumably the larger ones) did not gain access to the interior of the cells, many were phagocytized, and some enzyme was transferred to the cell membrane, perhaps as a result of fusion of the liposomal membrane with the cell membrane. PMID- 4138545 TI - Continuous ECG (Holter) recordings in the evaluation of antiarrhythmic drugs. PMID- 4138546 TI - [Radiochemical determination of the mercaptopurine content and thin layer chromatographic study of aggregation behaviour of mercaptopurine-protein conjugates]. PMID- 4138547 TI - [Radiotherapy of malignant melanoma]. PMID- 4138548 TI - [Radiotherapy of prostatic cancer (author's transl)]. PMID- 4138550 TI - Cardiovascular effects of halothane in the stump-tailed macaque during spontaneous and controlled ventilation. PMID- 4138549 TI - [Serious situations in hyperthyroidism (author's transl)]. PMID- 4138551 TI - Precipitating antibodies in anti-erythropoietin sera. PMID- 4138552 TI - [Oedipus and the time accepted]. PMID- 4138553 TI - Impairment by cholestyramine of dicumarol and tromexan absorption in rats: a potential drug interaction. PMID- 4138554 TI - The isolation of kidney brush border. PMID- 4138555 TI - [Antistaphylococcal gamma globulin in complex treatment of suppurative inflammatory staphylococcal diseases]. PMID- 4138556 TI - Conditions for optimal MTV synthesis in vitro and the effect of steroid hormones on virus production. PMID- 4138557 TI - In vitro cytotoxicity of human lymphocytes: reduction of the lymphocyte cytotoxicity induced by antibodies or phytohemagglutinin by removing immune complex-binding cells. PMID- 4138558 TI - Committee on Educational Affairs of ASBC. PMID- 4138559 TI - Calcium balance in pregnancy. PMID- 4138560 TI - [Podium discussion on the theme "Tissue preparation and fixation"]. PMID- 4138561 TI - Passive transport of the stria vascularis. PMID- 4138562 TI - Viral hepatitis--the state of the art. PMID- 4138564 TI - Cyril Wyllie Kesson. PMID- 4138563 TI - Fetal malformations and abnormalities. PMID- 4138565 TI - [Collagen as cosmetic compound? (author's transl)]. PMID- 4138566 TI - Nodular cutaneous reactive histiocytosis caused by an unidentified microorganism: report of a case. PMID- 4138567 TI - Vinblastine-induced blockage of orthograde and retrograde axonal transport of protein in retinal ganglion cells. PMID- 4138568 TI - Simulataneous occurrence of Neisseria gonorrhoeae, Candida albicans, and Trichomonas vaginalis. PMID- 4138569 TI - Shoulder-hand syndrome. PMID- 4138570 TI - Muscle fibrillation induced by blockage of axoplasmic transport in motor nerves. PMID- 4138571 TI - [Nuclear medicine in thyroid gland diagnosis]. PMID- 4138572 TI - Isoelectrofocusing of human plasma lipoproteins in polyacrylamide gels: diagnosis of type III hyperlipoproteinemia ("broad beta" disease). PMID- 4138573 TI - An electron microscopic investigation of the surface coat of visceral yolk sac endoderm cells in the guinea pig. PMID- 4138574 TI - An electrophoretic method for detection of unbound bilirubin and reserve bilirubin binding capacity in serum of newborns. PMID- 4138575 TI - Complement components and IgE in bronchial asthma. PMID- 4138576 TI - Peculiar secretory IgA system identified in chickens. PMID- 4138578 TI - Acrylic cement and the cardiovascular system. PMID- 4138577 TI - [Palliative chemotherapy of bronchial cancers. Current status of the problem]. PMID- 4138579 TI - Facility design and equipment considerations for the team practice of dentistry. PMID- 4138581 TI - Cytologic diagnosis in allergic disorders. PMID- 4138580 TI - The liver in kwashiorkor. A clinical and electron microscopical study. PMID- 4138582 TI - Serological responses of multiple-sclerosis patients and controls to a virus isolated from a multiple-sclerosis case. PMID- 4138583 TI - Cytology of rheumatoid synovial cells in culture. III. Significance of isolates of epithelial cell lines. PMID- 4138584 TI - Development of contact sensitivity to DNFB in guinea pigs genetically differing in their response to DNP skin protein conjugates. PMID- 4138585 TI - Development of immunotherapy for infections due to Pseudomonas aeruginosa. PMID- 4138586 TI - Is closed circuit TV a worth-while teaching aid? PMID- 4138588 TI - Results of studies using an on-line automatic analyzer of sleep stages in the rat. PMID- 4138587 TI - Simultaneous measurement of bromsulphalein initial distribution volume and 131I albumin plasma volume in patients with liver disease. A study of 195 patients and a review of the literature. PMID- 4138589 TI - [Cellular infiltrate and capillaries in atopic dermatitis. Quantitative enzyme cytochemical and histochemical investigations (author's transl)]. PMID- 4138590 TI - Triglyceride-lowering effect of chenodeoxycholic acid in patients with endogenous hypertriglyceridaemia. PMID- 4138591 TI - [Analysis of failures in the cryogenic surgery for prostatic adenoma. Evaluation of 157 operations]. PMID- 4138592 TI - [Analysis of the equations of excitable membranes. IV. Use of the null-isocline method for analysis of Purkinje fiber membranes (anode and cathode stimulation, extrasystoles)]. PMID- 4138593 TI - [Analysis of ECG-arrhythmia using a digital computer in actual time operation]. PMID- 4138594 TI - Serum insulin response to glucose infusion in hyperthyroid dogs. PMID- 4138595 TI - Serum protein pattern in Addis Ababa preschool children. PMID- 4138596 TI - Serum proteins: diagnostic significance of electrophoretic patterns. PMID- 4138597 TI - [Gamma globulins in the blood and colostrum in coli infections in calves and in immunized cows]. PMID- 4138598 TI - Plasma kinins and the jarisch-herxheimer reaction. PMID- 4138599 TI - Plasma testosterone levels and acne. PMID- 4138600 TI - [Primary optic pathways and centers in the snake (Vipera aspis)]. PMID- 4138601 TI - Traumatic encephalopathy in a young boxer. PMID- 4138602 TI - Automatic suppression of eye movement and muscle artifacts when averaging tape recorded cerebral evoked potentials. PMID- 4138603 TI - Estimation of chromatin patterns at G1, S, and G2 of the cell cycle. PMID- 4138605 TI - The medical management of hyperthyroidism. PMID- 4138604 TI - A membrane filter method for correlating colposcopic, histological, and cytological pictures: the application to nuclear DNA measurements. AB - A method is described for collecting cells on membrane filters in their natural topographical relationships, so that they can be correlated with exact areas in the cervix and with punch biopsy specimens. The same cell sample, after study with Papanicolaou stain, can then be used for other methods without the cells losing their spatial relationships. An example is given of an early cervical carcinoma in which, using a photographic method with a simple type of photometric device, the nuclear DNA was measured from accurately identified normal and neoplastic areas. PMID- 4138606 TI - The mentally retarded are not different. PMID- 4138607 TI - The metabolism of IgG(T) in the newborn foal. PMID- 4138608 TI - Endemic cretinism of recent onset in New Guinea. PMID- 4138609 TI - Dynamics of axoplasmic transport in the optic system of the rat. PMID- 4138611 TI - [Chemotherapy of mouth carcinomas--hope or reality]. PMID- 4138610 TI - An immunoelectron microscopy study of Soehner-Dmochowski murine sarcoma virus following passage in rats and hamsters. PMID- 4138612 TI - A comparative immunochemical study of the serum proteins of several Galapagos iguanids. PMID- 4138613 TI - A comparison of techniques for determining prenatal sex from liquor amnii. AB - The cellular content of amniotic fluid is primarily composed of desquamated squamous cells. Depending on their site of origin and maturation, the staining characteristics of the nuclei and cytoplasm differ. Prenatal foetal sex was determined by comparing the proportion of anucleate pyknotic nuclei to vesicular nuclei using Papanicolaou's stain and the proportion of red cells to blue cells using Shorr's stain.Both techniques allow an accurate assessment of prenatal sex to be made after 30 week's gestation. There is a close correlation between the two methods. PMID- 4138614 TI - A simple method for the preparation of antiserum to bovine immunoglobulins using immunosorbents. PMID- 4138615 TI - Attempts at morphological identification of the hemopoietic stem cell in rodents and primates. PMID- 4138616 TI - Attempts to measure plasmalemma and tonoplast electropotentials in small cells of the moss Mnium using centrifugation techniques. PMID- 4138617 TI - [Stimulation of thyroid iodine uptake with TSH]. PMID- 4138618 TI - Rat myelin proteins. Compositional changes in various regions of the nervous system during ontogenetic development. PMID- 4138619 TI - Zenon Buczowski. PMID- 4138620 TI - Diurnal changes in mitotic activity and DNA synthesis in normal and tumor tissues of rats. PMID- 4138621 TI - [Signal transmission by degenerating synapses following interruption of the axoplasmic flow. Studies on the corpus geniculatum laterale of the cat]. PMID- 4138622 TI - An analysis of some discriminative properties of d-amphetamine. PMID- 4138623 TI - B. Anathaswami Rao. PMID- 4138624 TI - The nature of Reed-Sternberg cells and other malignant "reticulum" cells. PMID- 4138625 TI - Infancy and childhood. PMID- 4138626 TI - Iodine contamination in iodometric measurements of thyroid hormones. PMID- 4138627 TI - Immune deposits in passive Arthus phenomenon. Electron microscopic demonstration by use of peroxidase-labeled antibody. PMID- 4138628 TI - Canine lipoproteins and atherosclerosis. I. Isolation and characterization of plasma lipoproteins from control dogs. PMID- 4138629 TI - Canine lipoproteins and atherosclerosis. II. Characterization of the plasma lipoproteins associated with atherogenic and nonatherogenic hyperlipidemia. PMID- 4138630 TI - Immune responses against native and chemically modified albumins in mice. II. Effect of electric charge and conformation on the humoral antibody response and on helper T cell responses. PMID- 4138631 TI - Iodine-induced toxic diffuse goitre. PMID- 4138633 TI - Strong stimulation of CBA lymphocytes in the mixed lymphocyte interaction with cells from the H-2-indentical strain C3H. PMID- 4138632 TI - Cutaneous uses of the antiproliferative drugs. PMID- 4138634 TI - An inhibitor of DNA polymerase which appears after inoculation of BALB-c mice with syngeneic tumors. PMID- 4138635 TI - Chronic septal hepatitis. PMID- 4138636 TI - Chronic sinusitis in children. Comments on pathogenesis and management. PMID- 4138637 TI - [Clinical and immunobiological studies of cysticercosis in cattle]. PMID- 4138638 TI - [Clinical experiences in the treatment of prostatic hypertrophy with high doses of progesterone administered rectally]. PMID- 4138639 TI - [Clinical observations on communicating hydrocephalus of unknown eitology (author's transl)]. PMID- 4138640 TI - [Clinical study of a new anti-arrhythmia agent: aprindine]. PMID- 4138641 TI - [Clinical-immunological and electron microscopic findings in Whipple's diseases (author's transl)]. PMID- 4138642 TI - [Clinico-anatomical correlation between sighting of the lesion and alleviation of pain following stereotactic surgery (author's transl)]. PMID- 4138643 TI - [Significance and value of scintigraphy in pulmonary diagnosis]. PMID- 4138644 TI - [Significance of the albumin concentration for the toxic effect of Evans blue and Congo red on thrombocytes]. PMID- 4138645 TI - Scanning immunoelectron microscopy of mouse B and T lymphocytes. PMID- 4138647 TI - [Amino-liberating capacity of bioflavonoids in various rat species]. PMID- 4138646 TI - Immunization against Pseudomonas in infection after thermal injury. PMID- 4138649 TI - [Quinolinones as starting products for pentacyclic heterocycles (author's transl)]. PMID- 4138648 TI - Immunobiology of colon carcinomas. PMID- 4138650 TI - Immunological demonstration of alpha-fetoprotein in uterine cytosol from immature rats. PMID- 4138651 TI - Immunological distinction between the possible origins of enzymatic activity in a polypeptide fragment of staphylococcal nuclease. PMID- 4138652 TI - Eosinophilic argentaffin cells in the human appendix. PMID- 4138654 TI - Prognostic value of estrogen receptor to endocrine ablation in cancer of the breast. PMID- 4138653 TI - Diagnostic electron microscopy of faeces. I. The viral flora of the faeces as seen by electron microscopy. AB - A method is described for examining viruses in faeces by direct electron microscopy using negative staining. The particles found in a group of patients with gastroenteritis and a group with other conditions are compared. Small particles in the range of sizes covering parvoviruses and enteroviruses were found about as frequently in each group. Many of these were probably bacteriophages. Many bacteriophages with tails of various sizes and lengths were found. Adenoviruses were found in five of eight patients from whom they were isolated. Reovirus- (or orbivirus-) like particles were found associated with some gastroenteritis patients. PMID- 4138655 TI - Immunosuppression with ethidium bromide: effect on lymphocyte blastogenesis and antibody plaque forming spleen cells. PMID- 4138656 TI - [Transport in the dendrites of single motor neurons]. PMID- 4138657 TI - Demonstration of geniculocortical and callosal projection neurons in the squirrel monkey by means of retrograde axonal transport of horseradish peroxidase. PMID- 4138658 TI - [Transurethral electroresection of adenomas of the prostate (results of the treatment of 700 patients)]. PMID- 4138659 TI - Client education. Technics in small animal practice. PMID- 4138660 TI - Ribonucleic acid. I. The test-tube synthesis of a viral nucleic acid. II. The development and use of molecular hybridization. PMID- 4138661 TI - A convenient stimulus and situation coding system for the tape recording of event related potentials. PMID- 4138662 TI - Radioautographic studies on the intracellular distribution of bleomycin-14C in mouse tumor cells. PMID- 4138663 TI - [Serochemical differential diagnosis of chronic liver diseases by means of discrimination analysis with special reference to the mesenchyma]. PMID- 4138664 TI - [Cytochemical localization of ATPases in a ciliate protozoan: ultrastructural study]. PMID- 4138665 TI - Histochemical studies of mucus-secreting cells in the gut of a coral fish, Chelmon rostratus Cuvier. PMID- 4138666 TI - Histochemical study on neural crest cells in mice embryos. PMID- 4138667 TI - Dissociation of lymphocyte activating determinants from recognition sites in mouse MLR. PMID- 4138668 TI - Carbocyanine dye metachromasia of sialidase-sensitive polyanions in sera from normal and tumor-bearing mice. PMID- 4138669 TI - Leucocyte histamine release studies and skin tests with aggregated gamma-globulin in hypogammaglobulinaemia. PMID- 4138670 TI - Oligodendroglial ensheathment of axons during myelination in the developing rat central nervous system. A serial section electron microscopical sttudy. PMID- 4138671 TI - Reproductive immunology. PMID- 4138672 TI - [Algodystrophic syndromes]. PMID- 4138673 TI - Use of selective, intrahepatic, portal venography and in vivo coloration in planning segmental hepatic resection. PMID- 4138675 TI - [Oncofetal antigens--and SF]. PMID- 4138676 TI - [Ontogeny of finger-sweat glands in man]. PMID- 4138674 TI - Use of DNA-DNA annealing to detect new virus-specific DNA sequences in chicken embryo fibroblasts after infection by avian sarcoma virus. AB - Labeled, virus-specific DNA synthesized in vitro by the virion-associated polymerase of avian sarcoma virus (ASV) was used to measure virus-specific sequences in cell DNA in three ways: (i) by determining the effect of cell DNA upon the reassociation rate of double-stranded polymerase products; (ii) by measuring the kinetics of annealing of single-stranded polymerase product (cDNA) to cell DNA; or (iii) by measuring the amount of cDNA which anneals to a large excess of cell DNA. With these three assays and modifications of them, we show that fewer than five copies of ASV-specific DNA sequences are present per diploid cell in uninfected chicken embryos; that a two- to several-fold increase in copy number of viral DNA follows infection by ASV; that infection introduces to the cell viral sequences not present before infection; and that DNAs from uninfected Pekin duck and Japanese quail embryos show no homology with DNA synthesized by the ASV polymerase. Some of these results differ from data in a previous report from this laboratory (H. E. Varmus, R. A. Weiss, R. R. Friis, W. Levinson, and J. M. Bishop, 1972) and, in general, reconcile our observations with those from other laboratories. PMID- 4138677 TI - Retrograde thalamic degeneration: observations using a modification of the Fink Heimer silver impregnation technique. PMID- 4138678 TI - Angiographic management of postoperative bleeding. PMID- 4138679 TI - Amyloid in normal and pathological parathyroid glands. AB - Two groups of parathyroid glands have been examined for intrafollicular amyloid. In glands removed surgically it was found in nine cases (16%); in glands removed at necropsy it was found in 23 cases (46%). Also, two postmortem cases of systemic amyloidosis showed involvement of parathyroid glands with an entirely different distribution of amyloid. Compared with other amyloids the tinctorial properties of the intrafollicular amyloid were uniform in reactions with Congo red and Thioflavin T, but the intensity of the staining reaction for amino acids tryptophan and tyrosine was not constant for the follicle amyloid. This variation may be a feature of a maturation process but the derivation of this amyloid remains uncertain. PMID- 4138680 TI - Thyroid physiology and functional tests. PMID- 4138681 TI - Thyroid-stimulating hormone binding to beef thyroid membranes. Relation to adenylate cyclase activity. PMID- 4138682 TI - Radioimmunoassay for the major structural protein of hamster type C viruses. AB - A radioimmunoassay for the major, group-specific antigen (p30) of hamster type C viruses was developed. The test detected approximately 5 ng of viral protein per ml and was highly specific for hamster viruses when used with homologous antibody. Comparison of three hamster viruses, two being mouse-hamster pseudotypes, in homologous and heterologous intraspecies assays, showed no evidence of type specificity for these proteins. The pseudotype viruses showed no evidence of mouse virus p30 antigenic determinants. An interspecies antigen assay employing (125)I-labeled hamster p30 and anti-feline p30 was completely inhibited by cat (feline leukemia virus), hamster, and rat viruses, to a slightly lesser degree by mouse viruses, and only poorly by RD 114 and Gibbon ape viruses. The Mason-Pfizer virus did not inhibit this assay. Hamster p30 was detected by radioimmunoassay in individual embryos from two LSH hamsters and in several adult tissues, excluding muscle at levels below that required for detection in complement-fixation tests. PMID- 4138683 TI - Radioimmunoassay of alpha fetoprotein in the diagnosis of malignancy. PMID- 4138685 TI - [Embolization of the renal artery. Experimental study. Use in the treatment of kidney cancers]. PMID- 4138684 TI - A cholinergic mechanism in the spinal cord of cats. PMID- 4138686 TI - Histological findings in parakeratosis pustulosa. PMID- 4138687 TI - Anatomopathologic basis for the cryosurgery of the prostate. PMID- 4138688 TI - [Cytomorphologic findings in juvenile rheumatoid arthritis]. PMID- 4138689 TI - [Cytomorphological characteristics of cellular elements of the normal pancreas]. PMID- 4138690 TI - Proton evolution associated with the photooxidation of water in photosynthesis. PMID- 4138691 TI - Regional monitoring of ambient air carbon monoxide in Fairbanks, Alaska. PMID- 4138692 TI - Anthony Richard May. PMID- 4138693 TI - Macrophage-lymphocyte clusters in the immune response to soluble protein antigen in vitro. AB - We have studied the physical interaction between macrophages and lymphocytes during the immune response to purified protein derivative of tuberculin (PPD) in vitro. Mixtures of peritoneal macrophages and lymph node lymphocytes from guinea pigs immunized with tubercle bacilli formed cell clusters during 20 h of culture with PPD. The number of clusters produced was correlated to the number of immune lymphocytes in the cultures. Peritoneal macrophages which had been pulsed with PPD and untreated lymph node lymphocytes produced cell clusters in the absence of free PPD in numbers equivalent to those produced by the same cells in the presence of free PPD. In cultures containing a mixture of PPD-pulsed macrophages, not-pulsed macrophages, and immune lymphocytes with no free PPD, cell clusters developed mainly between the antigen-pulsed macrophages and lymphocytes. Cluster formation was antigen-specific with the specificity residing in the lymphocytes, mainly or exclusively in the T lymphocytes. These data indicate that in the process of cell cluster formation macrophages serve as antigen-binding (or processing) cells, while a subpopulation of lymphocytes interact physically and specifically with the macrophages. PMID- 4138694 TI - Macrophage-lymphocyte clusters in the immune response to soluble protein antigen in vitro. II. Ultrastructure of clusters formed during the early response. AB - Macrophage-lymphocyte clusters are formed when lymph node cells and autologous peritoneal exudate cells from guinea pigs immunized with tubercle bacilli are cultured in the presence of purified protein derivative of tuberculin (PPD) for 20 h. We have studied the ultrastructure of these clusters employing transmission and scanning electron microscopy. The most simple macrophage-lymphocyte cluster consisted of one macrophage, one large central lymphocyte with a blastoid appearance attached to the macrophage with a broad area of contact, and from a few to more than 20 small peripheral lymphocytes attached to the central lymphocyte by their uropods. Some clusters were of more complex type, containing two or three macrophages or one macrophage with more than one central lymphocyte attached to the surface, but even in these clusters each peripheral lymphocyte was attached only to one central lymphocyte. By morphological criteria the peripheral lymphocytes were T lymphocytes. PMID- 4138695 TI - Leukoplakia of the bladder: an 8-year follow-up. PMID- 4138696 TI - [Apropos of 30 observations on prostatic cryosurgery]. PMID- 4138698 TI - Microradiographic study of the normal human vertebral body. PMID- 4138697 TI - Factor VIII-related antigen in tissues detected by the indirect immunofluorescence technique. PMID- 4138699 TI - Temporal effects of artificial induction of ovulation on the hypothalamo hypophysial-ovarian system of the catfish, Heteropneustes fossilis (Bloch). PMID- 4138700 TI - Editoral: Alpha-fetoprotein in primary carcinoma of the liver and other diseases. PMID- 4138701 TI - Editoral: Bodies offered for research. PMID- 4138702 TI - Editoral: Postoperative immunosuppression. PMID- 4138703 TI - Restoration of immune competence in tolerant mice by parabiosis to normal mice. AB - These studies demonstrate that mice tolerant to human gamma globulin (HGG) regain their ability to make antibody to HGG after parabiosis to normal mice. This can be demonstrated by enumeration of PFC in the spleens of both the normal and tolerant partners. Hemagglutinin titers of normal-tolerant parabionts, however, are exceptionally low; serum antibody appears to be neutralized by circulating HGG present originally in the serum of the tolerant partner. These data support the hypothesis that tolerance to HGG in mice is a "defective" state due to the absence of cells capable of responding to this antigen. PMID- 4138704 TI - Explorations of a systems approach to alcoholism. Clinical observations of a simulated drinking gang. PMID- 4138705 TI - [Laboratory studies in alveolitis and pulmonary fibrosis (with particular regard to immunologic methods]. PMID- 4138706 TI - [Fluorescence diagnosis of sex chromosomes in the XYY syndrome]. PMID- 4138707 TI - Editorial: Acids, bases, and nomograms. PMID- 4138708 TI - Editorial: Antibiotics for disease. PMID- 4138709 TI - Editorial: Beta-blockade and size of acute myocardial infarction. PMID- 4138710 TI - Editorial: Computer-assisted tomography of the brain. PMID- 4138711 TI - Editorial: Conservative operations for diverticular disease. PMID- 4138712 TI - Editorial: Epilepsy, schizophrenia, and limbic system. PMID- 4138713 TI - Editorial: Little light on phototherapy. PMID- 4138714 TI - Editorial: Nephrocalcinosis and renal tubular acidosis. PMID- 4138715 TI - Editorial: Only black grapes. PMID- 4138716 TI - Editorial: Optic neuritis of obscure origin. PMID- 4138717 TI - Editorial: Progress with an artificial liver. PMID- 4138718 TI - Editorial: Proliferating and phagocytic histiocytes. PMID- 4138719 TI - Editorial: Scoliosis. PMID- 4138720 TI - Editorial: Self-injury. PMID- 4138722 TI - Editorial: Social-work support for the Health Service. PMID- 4138721 TI - Editorial: Sloth's compensations. PMID- 4138723 TI - Editorial: Starling's law survives. PMID- 4138724 TI - Editorial: The patients we don't see. PMID- 4138725 TI - Editorial: The pill off prescription? PMID- 4138726 TI - Editorial: The specialty of infectious diseases. PMID- 4138727 TI - Editorial: Viruses and heart-disease. PMID- 4138728 TI - Desmosome-like structures in acantholytic epidermal cells of contact dermatitis. PMID- 4138729 TI - A glossary of terms most commonly used by clinical electroencephalographers. PMID- 4138730 TI - [Cryotherapy in the treatment of prostatic obstructions in patients with increased surgical risk. Considerations on 200 additional cases]. PMID- 4138731 TI - [Cryotherapy of urinary retention in inoperable patients]. PMID- 4138732 TI - [Dicoumarol as the cause of abortion in mink (author's transl)]. PMID- 4138733 TI - Bullous scabies. PMID- 4138734 TI - [Preparation of mercaptopurine-protein conjugates from 5-mercaptopurine derivatives with an isothiocyanate group. 2. Immune suppressive antigen conjugates]. PMID- 4138735 TI - [Comparative elctrophoretic studies on blood sera of weaned lambs infested with Melophagus ovinus]. PMID- 4138736 TI - [Comparative electrophoretic studies using a veronal buffer and a mediator of carboxymethylcellulose]. PMID- 4138737 TI - [Comparative studies of Aujeszky's virus in cell culture]. PMID- 4138738 TI - [Comparison of aprindine (AC 1802) and lidocaine by intravenous route during the acute phase of myocardial infarct]. PMID- 4138739 TI - [Comparison of 2 methods of staining of Trichomonas vaginalis for purposes of medical diagnosis and didactics]. PMID- 4138740 TI - The peribrachial region of cat. I. A topographical study with special reference to the locus coeruleus. PMID- 4138741 TI - The pharmacology and clinical evaluation of aprindine a new antiarrhythmic agent. PMID- 4138742 TI - The phenomenon of premature chromosome condensation: its relevance to basic and applied research. PMID- 4138743 TI - [Morphologic studies of the influence of ultrasound upon the growing rabbit's larynx (author's transl)]. PMID- 4138744 TI - [Morphological and enzyme-histochemical data following the administration of a xenogenic antithymocyte serum to inbred mice]. PMID- 4138745 TI - [Morphological basis of a possible mode of transfer for DNA during the conjugation of star-forming soil bacteria (author's transl)]. PMID- 4138746 TI - [Morphological-physiological investigation on the effect of 5-azacytidine in the nucleolus]. PMID- 4138747 TI - [Morphology and histochemistry of synapses in the range of the intestinal tract (author's transl)]. PMID- 4138748 TI - Polyphosphate bone scans, 32phosphorus, and adenocarcinoma of the thyroid. PMID- 4138749 TI - Cytophotometric factors causing apparent differences between Feulgen DNA contents of different leukocyte types. PMID- 4138750 TI - Atrophy of the stria vascularis, a common cause for hearing loss. PMID- 4138751 TI - The physiological role of gamma-globulin. PMID- 4138752 TI - Ectopic subvesical prostatic tissue. PMID- 4138753 TI - Whipple's disease. George Hoyt Whipple, (born 1878). PMID- 4138754 TI - Paraplegia in carcinoma of the prostate. PMID- 4138755 TI - [Symposium: Axoplasmic flow and synaptic transmission. General conclusions]. PMID- 4138756 TI - [Whipple's disease. Digestive bioptic and histochemical findings in a case]. PMID- 4138757 TI - The preparation of matrix-bound proteases and their use in the hydrolysis of proteins. PMID- 4138758 TI - The prognostic importance of premature ventricular complexes in the late post infarction period. Experience in the Cornary Drug Project. PMID- 4138759 TI - The prognostic significance of ventricular premature contractions in healthy people and in people with coronary heart disease. PMID- 4138760 TI - The properties of ionic channels measured by noise analysis in thin lipid membranes. PMID- 4138761 TI - Asymptomatic arteritis of the uterine cervix. AB - A necrotizing arteritis in the uterine cervix is described as an incidental finding in surgical material from 10 patients. The histological features are compared with those seen in polyarteritis nodosa. Subintimal hyaline deposition and a relative paucity of neutrophil and eosinophil polymorphs characterized the lesion but the histological appearance was never sufficiently specific to exclude confidently the possibility of polyarteritis nodosa. None of the patients had evidence of multisystem disease either at the time of operation or at subsequent follow-up assessment. PMID- 4138762 TI - Receptor sites for aggregated gammaglobulin (AGG) on lymphocytes in lymphoproliferative diseases. PMID- 4138763 TI - The pyridine-nucleotide transhydrogenase of Salmonella typhimurium. PMID- 4138764 TI - Lower-oesophageal-sphincter relaxation is a myth. PMID- 4138765 TI - [Characteristics of the course of toxic hepatitis caused by the long-term effects of hexachlorcyclohexane (HCCH) preparations]. PMID- 4138766 TI - Contractile structures in endothelial cells of splenic sinusoids. PMID- 4138768 TI - [Intradermal tuberculin RT-23 test in patients with leukemia]. PMID- 4138769 TI - The radioallergosorbent test (RAST): diagnostic and clinical significance. PMID- 4138770 TI - Lateral amygdala unit acitvity: I. Relationship between spontaneous and evoked activity. PMID- 4138771 TI - Lateral amygdala unit activity: II. Habituating and non-habituating neurons. PMID- 4138772 TI - General and specific patterns of acrocentric association in parents of mongol children. PMID- 4138773 TI - General aspects of anti-arrhythmic treatment with aprindine. PMID- 4138774 TI - Generalized mastocytosis. PMID- 4138775 TI - Propranolol in the surgical management of thyrotoxicosis. AB - Forty-nine thyrotoxic patients prepared for partial thyroidectomy with the beta adrenoceptor blocking drug, propranolol, and iodine are compared with 42 patients prepared with carbimazole and iodine. The age and sex distribution of the two groups were comparable, but patients with obstructive airways disease and possible cardiac insufficiency were excluded from preparation with propranolol. The mean duration of preoperative treatment with propranolol was 40 days, compared with 89 days for carbimazole. Propranolol treated patients had lower pulse rates before and after operation. The serum PB(127)I values immediately before and after operation were higher in the propranolol group than in the carbimazole group, but were the same in both groups one and four months after operation. The incidence of hypothyroidism at one year after operation was 30% in the carbimazole prepared patients and 31% in the propranolol patients. Serum calcium levels were higher in the propranolol group at the time of operation. No adverse effects from the use of propranolol and at operation the thyroid gland prepared with propranolol was firmer, less friable, more easily mobilised and less likely to bleed than the gland prepared with carbimazole. There is, consequently, less risk of damage to the parathyroid glands and recurrent laryngeal nerves. However, the basal metabolic rate remains high on propranolol therapy and very careful supervision is advised. PMID- 4138776 TI - [Therapy of bronchial epidermoid carcinoma with bleomycin (25 cases)]. PMID- 4138777 TI - [Ultrastructural and cytochemical studies of bacteroid differentiation of Rhizobium trifolii Dangeard in the nodules of Trifolium repens L]. PMID- 4138778 TI - [Ultrastructural changes in skeletal muscles in experimental gas gangrene with Clostridium perfringens (author's transl)]. PMID- 4138779 TI - [Ultrastructure of inborn errors of keratinization. V. Ichthyosis in Refsum's syndrome (heredopathia atactica polyneuritiformis) (author's transl)]. PMID- 4138780 TI - Alteration of keratinization in mouse ear epidermis in recombinant grafts with tail dermis. PMID- 4138781 TI - Separation of water soluble proteins in psoriatic scales with different polyacrylamide gel concentrations and molecular weight estimations of the separated bands by disc-electrophoresis. PMID- 4138782 TI - Alterations in serum proteins of rats after immunization with Freund's adjuvant and Bordetella pertussis vaccine. PMID- 4138783 TI - Ulcerative lichen planus of the feet. A case in which the serological findings suggested systemic lupus erythematosus. PMID- 4138784 TI - Hypercalcemia associated with gaint condyloma accuminatum. PMID- 4138785 TI - The reaction of rheumatoid anti-Gm antibodies with native and aggregated Gm negative IgG. PMID- 4138786 TI - Age-related variation in proportion of circulating T cells. PMID- 4138787 TI - [Current problems in the diagnosis of adenoma of the prostate]. PMID- 4138788 TI - The repression of medical science in absolutist Spain: the case of Juan Manuel de Arejula 1755-1830. PMID- 4138789 TI - The retrograde intraaxonal transport of horseradish peroxidase in the chick visual system: a light and electron microscopic study. PMID- 4138790 TI - Allergy versus clinical immunology: a critical analysis. PMID- 4138791 TI - Experimental hepatic porphyria induced by hexachlorobenzene as a model for human symptomatic porphyria. PMID- 4138792 TI - Inherited metabolic disease. PMID- 4138793 TI - Determination of the defective function in two mutants of Rous sarcoma virus. PMID- 4138794 TI - International Federation of Societies for Electroencephalography and Clinical Neurophysiology. PMID- 4138795 TI - Scleroderma in the child. PMID- 4138796 TI - Heterogeneity of carcinoembryonic antigen and its fractionation by con A affinity chromatography. PMID- 4138797 TI - [Thyroid gland hormones--thyreostatic drugs]. PMID- 4138799 TI - Control of diesel exhaust odors. PMID- 4138798 TI - [Thyroid reserve in children with progressive rheumatoid arthritis based on the determination of the level of iodine bound to blood proteins]. PMID- 4138800 TI - The role of langerhans cells in contact allergy. I. An ultrastructural study in actively induced contact dermatitis in guinea pigs. PMID- 4138801 TI - Argyrophil mucus-secreting adenocarcinoma of the colon and sebocystomatosis: report of a case. PMID- 4138802 TI - Chloroplast and cytoplasmic ribosomes of Euglena: selective binding of dihydrostreptomycin to chloroplast ribosomes. AB - Dihydrostreptomycin binds preferentially to chloroplast ribosomes of wild-type Euglena gracilis Klebs var. bacillaris Pringsheim. The K(diss) for the wild-type chloroplast ribosome-dihydrostreptomycin complex is 2 x 10(-7) M, a value comparable with that found for the Escherichia coli ribosome-dihydrostreptomycin complex. Chloroplast ribosomes isolated from the streptomycin-resistant mutant Sm(1) (r)BNgL and cytoplasmic ribosomes from wild-type have a much lower affinity for the antibiotic. The K(diss) for the chloroplast ribosome-dihydrostreptomycin complex of Sm(1) (r) is 387 x 10(-7) M, and the value for the cytoplasmic ribosome-dihydrostreptomycin complex of the wild type is 1,400 x 10(-7) M. Streptomycin competes with dihydrostreptomycin for the chloroplast ribosome binding site, and preincubation of streptomycin with hydroxylamine prevents the binding of streptomycin to the chloroplast ribosome. These results indicate that the inhibition of chloroplast development and replication in Euglena by streptomycin and dihydrostreptomycin is related to the specific inhibition of protein synthesis on the chloroplast ribosomes of Euglena. PMID- 4138803 TI - Nephrotoxic canine glomerulonephritis. PMID- 4138804 TI - [Thyrotropin in serum. Methodology and clinical value]. PMID- 4138805 TI - [Aberrant ventricular complexes]. PMID- 4138806 TI - Robertsonian translocation between the chromosome Y and 15. PMID- 4138807 TI - Instruction in oral hygiene--a group approach. PMID- 4138808 TI - Observations on axoplasmic transport in rabbits with aluminum-induced neurofibrillary tangles. PMID- 4138809 TI - Observations on carcinoma of the oesophagus. PMID- 4138810 TI - Observations on the use of solid-phase-coupled antibodies in the radioimmunoassay of human placental lactogen. AB - A detailed comparative assessment was made of the use of solid-phase-coupled antibodies in radioimmunoassay, by using an assay for human placental lactogen as a model system. The major advantages of the solid-phase technique are: (1) in common with the use of a second antibody, it is universally applicable; (2) separation can be carried out rapidly; (3) in contrast with some other techniques, the separation of antibody-bound and free antigen is virtually complete. The disadvantages when compared with other procedures are: (1) a considerable proportion of the antibody may be lost during the initial coupling reaction; (2) the tubes must be continuously mixed during incubation, and much effort is expended in removing and replacing the caps; (3) there is a decrease in the apparent affinity constant of the antibody after coupling, which is reflected in a lower sensitivity of the assay system. It is concluded that solid-phase antibodies are of greatest value in those systems in which the supply of antiserum is abundant, and in which the achievement of high sensitivity is not a requirement. PMID- 4138811 TI - Mucus catheter with a protective guard. PMID- 4138813 TI - Class specificity of intracellular and surface immunoglobulin of cells in popliteal and intestinal lymph from sheep. PMID- 4138812 TI - Tests for penicillin allergy in man. II. The immunological cross-reaction between penicillins and cephalosporins. PMID- 4138814 TI - Warts. Biology and current therapy. PMID- 4138815 TI - Lupus-like syndromes induced by drugs. PMID- 4138816 TI - Cross-reactivity of synthetic linear dextran with anti-B512 dextran. Viewpoints on the nature of the antigenic determinants of dextran. PMID- 4138817 TI - Cross-reactivity of the axial filament antigen as a criterion for classification of Leptospira. PMID- 4138818 TI - Giemsa banding of 'normal' leukaemic chromosomes: a preliminary report. PMID- 4138819 TI - Polysaccharide surface coat (glycocalix) of human placental villi. PMID- 4138820 TI - A case of brain fever. PMID- 4138821 TI - A case of irreversible bilateral optic damage after ethambutol therapy. PMID- 4138822 TI - [Disseminated lenticular dermatofibrosis with osteopoikilia. Buschke--Ollendorff syndrome]. PMID- 4138823 TI - [Conservative or surgical treatment of coronary heart disease? An attempt of critical analysis of current situation]. PMID- 4138824 TI - The severe form of alpha thalassaemia is caused by a haemoglobin gene deletion. PMID- 4138826 TI - Transplantation and the ageing kidney. PMID- 4138825 TI - Non-specific stimulation of immunoglobulin synthesis in mice by capsular polysaccharide of Klebsiella pneumoniae. PMID- 4138827 TI - Remission of familial goitrous hypothyroidism. PMID- 4138828 TI - Assessment of cadaveric kidneys for transplantation. PMID- 4138829 TI - Assessment of human renal transplantation. PMID- 4138830 TI - A post-hysterectomy syndrome. PMID- 4138831 TI - [Prostatic adenomectomy in patients with an implanted EKS-2 pacemaker]. PMID- 4138832 TI - [Prostatic adenoms. Instrumental and surgical therapy]. PMID- 4138833 TI - Resistotyping of Proteus mirabilis and a comparison with other methods of typing. AB - Resistotyping of P. mirabilis using 10 compounds is reported. The method was tested for reproducibility and specificity and results were compared with those obtained by serological, bacteriophage, and proticine typing methods and the Dienes test. The possible relationship between resistance to the chemicals used in the test and antibiotics was also studied.The method was found to be simple, reproducible, show good specificity, and compare favourably with other typing methods. No linkage between resistance to the chemicals and antibiotic resistance was detected. PMID- 4138834 TI - The structure and growth of valve-pocket thrombi in femoral veins. AB - The structure of 50 small thrombi in femoral valve pockets and the microscopic contents of 35 apparently empty pockets were studied in an attempt to ascertain the nature of the microscopic nidi from which thrombi form and their manner of growth to visible thrombi. Sixteen thrombi had little or no cellular invasion. Most of these recent structures had two main regions, red areas restricted distally in the pocket by the vein wall, and larger white regions comprising most of the thrombus length and often covering the red areas. Red areas are the early sites of cellular adhesion and invasion and the likely sites of origin of most thrombi. They were usually dominated by red cells and fibrin. White zones, which represent propagation growth, are characterized by many foci of platelets with fibrin borders (platelet-fibrin units). Some red areas also contained platelet fibrin units but they were few and tiny; platelets were not seen in others and one small wholly red thrombus was devoid of platelets. Degenerative changes in platelet-fibrin units were observed, and it is postulated that many become purely fibrin structures. There was no significant evidence of preceding intimal damage in the vein wall. Therefore nidi are laid down on normal endothelium probably on the vein wall near the apex of the pocket. Some pockets, empty of thrombi, contained condensed foci of red cells or tiny fibrin fragments surfaced by endothelial cells and considered to be the remnants of aborted thrombi; a few contained clumps of platelets or leucocytes. It is postulated that any of these may represent the nidi from which thrombi grow. Several thrombi also incorporated large fat droplets, numerous in two. Fat embolic globules derived from fractures are their likely source. PMID- 4138835 TI - Cryosurgery of the prostate, a four years follow-up study. PMID- 4138836 TI - The surgical significance of thyroid isotopology: morphologic and physiologic considerations. PMID- 4138837 TI - Light, scanning, and transmission electron microscopy of stable staphylococcal L forms. PMID- 4138838 TI - Prostate cancer. PMID- 4138839 TI - [Gestation time prolonging effect of progesterone and various synthetic gestagens in the rat]. PMID- 4138840 TI - [Acute hallucinations from treatment with bleomycin]. PMID- 4138841 TI - Unintegrated murine leukemia viral DNA in newly infected cells. PMID- 4138842 TI - [Content of total iodine, its hormonal, nonhormonal compounds and the state of tissue sulfhydryl groups in the chorion and placenta in physiological pregnancy]. PMID- 4138843 TI - The termination of immunologic unresponsiveness to the cyanogen bromide fragments of bovine serum albumin in rabbits. PMID- 4138844 TI - Growth responses of selected quail lines to goitrogenic stresses. PMID- 4138846 TI - [On the effectivity in vitro of heterologous rabbit antisera against mouse leukemia cells (author's transl)]. PMID- 4138845 TI - [On the activity of phospholipase A2 compared with 1-alk-1'-enyl-2-acyl- and 1 alkyl-2-acyl-glycerophosphatides in multiple sclerosis (author's transl)]. PMID- 4138847 TI - [On the therapy of special malformations of the aortic isthmus (author's transl)]. PMID- 4138848 TI - Endothelial cell morphology in focal areas of in vivo Evans blue uptake in the young pig aorta. I. Quantitative light microscopic findings. PMID- 4138849 TI - Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides. AB - In vivo immune responses and in vitro mitogenic responses to bacterial lipopolysaccharides (LPS) have been compared in strains of C3H mice. C3H/HeJ spleen cultures did not support mitogenic responses to LPS and in vivo these mice produce low IgM responses to LPS. On the basis of these two responses, C3H/HeJ mice have been termed low LPS responders. All other strains of C3H mice tested (C3HeB/FeJ, C3H/DiSn, C3H/Str, CWB, CSW, and C3H/Sf and its H-2 congenics) are high LPS responders supporting large in vitro mitogenic and in vivo immune responses to LPS. The immune response difference between low and high LPS responders is a quantitative one. IgM responses are observed in C3H/HeJ mice in the range of 1.0-10 microg LPS. At lower and higher LPS concentrations, immune responses are not observed. In contrast, high LPS responders elicit LPS immune responses over a much wider dose range (0.1-200 microg). The ability to respond well to LPS is dominant as shown by the response of F(1) hybrid mice of low responder and high responder strains. The linkage relationships of mitogenic and immune responsiveness to LPS have been investigated in backcross (C3H/HeJ x CWB)F(1) x CWB mice. All mice that gave in vivo immune responses to LPS also supported mitogenic responses to LPS. The defect in C3H/HeJ mice that limits mitogenic and immune responsiveness to be due to a single autosomal gene which is not linked to the H-2 histocompatibility or heavy-chain allotype loci. PMID- 4138851 TI - Practical aspects of the hepatitis B problem. PMID- 4138850 TI - Genetic mapping of the antigenic determinants of two polysaccharide K antigens, K10 and K54, in Escherichia coli. AB - The genes controlling synthesis of the Escherichia coli acidic polysaccharide capsular antigens K10 and K54 were transferred by conjugation to E. coli strains of other serotypes. The genes concerned with these K antigen determinants showed genetic linkage with the serA locus. We propose to name the K antigen-controlling gene kpsA. The genetic determinants of the two K antigens could also be transferred to enteropathogenic serotypes, even though such strains have never been found in nature with special acidic polysaccharide K antigens. A noncapsulated derivative, K(-), of the K10 strain can transfer the genetic determinant of the K antigen, demonstrating the probable existence of another chromosomal locus involved in the production of such acidic polysaccharide K antigens. PMID- 4138852 TI - [Testicular histology, ejaculate and nucleoprotein content of spermatozoa in patients with treated testicular tumors]. PMID- 4138853 TI - Identification by peroxidase staining of monocytes in surface immunofluorescence tests. PMID- 4138854 TI - Identification of chloroplast coupling factor by freeze-etching and negative staining techniques. AB - Identification of chloroplast coupling factor particles, by the freeze-etching and negative-staining techniques, was made utilizing chloroplast thylakoids isolated from spinach leaves. Complete removal of particles, comparable in diameter to purified coupling factor particles, from the outer surface of freeze etched thylakoids was achieved by treatment with 0.8% silicotungstate. Reappearance of particles, comparable in diameter to purified coupling factor particles, on the outer surface of freeze-etched thylakoids was demonstrated by combining silicotungstate-treated thylakoids with purified chloroplast coupling factor. Negative-staining results were in agreement with the freeze-etch data. The results demonstrate that the chloroplast coupling factor particles are exposed on the outer surface. PMID- 4138855 TI - Identification of discrete classes of normal human peripheral lymphocytes by multiparameter flow analysis. PMID- 4138856 TI - Identification of monoaminergic fluorescent neurons by azan-staining in the cerebral ganglion of the earthworm, Allolobophora caliginosa. PMID- 4138857 TI - Identification, enumeration, and isolation of B and T lymphocytes from human peripheral blood. Report of a WHO-IARC-sponsored workshop on human B and T cells, London, 15-17 July 1974. PMID- 4138858 TI - Fixation with mercury salts. PMID- 4138859 TI - Functional cellular maturation in cultures of human haematopoietic cells. PMID- 4138860 TI - Functional changes of the neuronal and glial elements at the surface of the external layer of the median eminence. PMID- 4138861 TI - Quantitative thin-layer gel filtration applied to gamma-globulin preparations. PMID- 4138862 TI - Reactivity of steroid-resistant neonatal thymocytes. PMID- 4138863 TI - Treatment of chronic ventricular dysrhythmias with a new drug: aprindine (AC 1802). PMID- 4138864 TI - [Histochemical studies on the formation of mucoid substances in the gastric mucosa in uremia]. PMID- 4138865 TI - [Histochemical technic of Hematoxylin-Basic Fuchsin-Picric acid (HBFP) in the study of sudden death due to myocardial ischemia]. PMID- 4138866 TI - [Postoperative complications of perineal prostatic adenomectomy]. PMID- 4138867 TI - [Editorial: Glycogenosis]. PMID- 4138868 TI - Monitoring odorous air pollution in the field with human observers. PMID- 4138869 TI - Endotoxin-induced intravascular coagulation and shock in dogs: the role of factor VII. PMID- 4138871 TI - The treatment of bacterial endophthalmitis following retinal surgery. PMID- 4138870 TI - Penetration of pollutants in the airways. PMID- 4138872 TI - [Contribution of the immunologic assessment to the prognosis of primary bronchial cancers]. PMID- 4138873 TI - [Contribution to pathohistology of the extrinsic ocular muscles in myasthenia gravis pseudoparalytica (author's transl)]. PMID- 4138874 TI - Electroencephalographic activity of caimans as related to diving. PMID- 4138875 TI - Electron microscopic observations of melanin transfer in human skin. Evidence for indirect melanin transfer. PMID- 4138876 TI - Electron translucent vesicles in adrenal medulla following catecholamine depletion. PMID- 4138877 TI - Electrophoretic pattern of equine cerebrospinal fluid. PMID- 4138878 TI - Electrophysiologic basis of arrhythmias: a clinical correlation. PMID- 4138879 TI - Substructures and polypeptides of Visna virus. AB - The protein of Visna virus, disrupted by 8 M guanidine hydrochloride and heating, was resolved into 10 polypeptides by agarose gel column chromatography in 6 M guanidine hydrochloride. Two of the peaks contained glycopolypeptides. Nonidet disrupted virions were resolved into two fractions by potassium tartrate gradient centrifugation, with densities of 1.08 and 1.24 g/ml, respectively. About 70% of the viral DNA polymerase directed by added template was released into the light fraction, in which very little endogenous enzyme activity was detected. Also released into the light fraction were all of the glycopolypeptides, 50% of the viral RNA, and a part of each of the other viral protein components. The data indicate that extensive degradation of subviral structures occurred, even under mild conditions for virion disruption. The 1.24-g/ml fraction was composed of 50% of the viral RNA, most of the endogenous DNA polymerase activity (80%), and a major internal polypeptide (GuHCl6) with an estimated mol wt of 28,000. Two other polypeptides were also consistently detected in the heavy fraction, but they constituted less than 25% of the ribonucleoprotein complex, compared with 75% for GuHCl6. PMID- 4138880 TI - Idiotypic uniformity of cell surface immunoglobulin in chronic lymphocytic leukeima. Evidence for monoclonal proliferation. PMID- 4138881 TI - Serotyping of adenoviruses using immune electron microscopy. AB - Immune electron microscopy may be used to determine the type specificity of several common human adenoviruses. The method described utilized equine antisera and was used to serotype adenoviruses within hours after typical cytopathic effect was observed in tissue culture. Adenovirus types 1, 2, 3, 5, 7a, 8, and 11 were isolated from clinical specimens and serotyped by serum neutralization and immune electron microscopy. Five of the seven types were identified consistently and identically by the two methods. Types 7a and 11 were indistinguishable by immune electron microscopy. PMID- 4138882 TI - Unusual inclusions occurring in the blasts of four patients with acute leukemia and Down's syndrome. PMID- 4138883 TI - Production of C and T bands in human chromosomes after heat treatment at high pH and staining with "stains-all". PMID- 4138884 TI - [Structural-functional unit of epicardiac paraganglia in man of different age]. PMID- 4138886 TI - A study of lead concentrations in blood of children (and some adults) of Southern Tasmania. PMID- 4138885 TI - [Structure on DNA of RNA polymerase-binding sites (author's transl)]. PMID- 4138887 TI - [Value of iodine-I-123 in the examination of thyroid function]. PMID- 4138888 TI - Tissue-culture microtest for predicting response of human cancer to chemotherapy. PMID- 4138889 TI - Influence of glutaraldehyde and-or osmium tetroxide on cell volume, ion content, mechanical stability, and membrane permeability of Ehrlich ascites tumor cells. AB - Effects of fixation with glutaraldehyde (GA), glutaraldehyde-osmium tetroxide (GA OsO(4)), and osmium tetroxide (OsO(4)) on ion and ATP content, cell volume, vital dye staining, and stability to mechanical and thermal stress were studied in Ehrlich ascites tumor cells (EATC). Among variables investigated were fixation time, fixative concentration, temperature, osmolality of the fixative agent and buffer, total osmolality of the fixative solution, osmolality of the postfixation buffer, and time of postfixation treatment in buffer (Sutherland, R. M., et al. 1967. J. Cell Physiol.69:185.). Rapid loss of potassium, exchangeable magnesium, and ATP, and increase of vital dye uptake and electrical conductivity occurred with all fixatives studied. These changes were virtually immediate with GA-OsO(4) or OsO(4) but slower with GA (in the latter case they were dependent on fixative temperature and concentration) (Foot, N. C. 1950. In McClung's Handbook of Microscopical Technique. 3rd edition. 564.). Total fixative osmolality had a marked effect on cell volume with OsO(4) but little or no effect with GA or GA OsO(4). Osmolality of the buffer had a marked effect on cell volume with OsO(4), whereas with GA or GA-OsO(4) it was only significant at very hypotonic buffer osmolalities. Concentration of GA had no effect on cell volume. Osmolality of the postfixation buffer had little effect on cell volume, and duration of fixation or postfixation treatment had no effect with all fixatives. Freezing and thawing or centrifugal stress (up to 100,000 g) had little or no effect on cell volume after all fixatives studied. Mechanical stress obtained by sonication showed that OsO(4) alone produced poor stabilization and that GA fixation alone produced the greatest stabilization. The results indicate that rapid membrane permeability changes of EATC follow fixative action. The results are consistent with known greater stabilizing effects of GA on model protein systems since cells were also rendered relatively stable to osmotic stress during fixation, an effect not noted with OsO(4). After fixation with GA and/or OsO(4) cells were stable to osmotic, thermal, or mechanical stress; this is inconsistent with several earlier reports that GA-fixed cells retain their osmotic properties. PMID- 4138890 TI - Influence of hydralazine consumption on allylamine induced myocardial fibrosis and hypertrophy in rats. PMID- 4138891 TI - Influence of passive smoking and parental phlegm on pneumonia and bronchitis in early childhood. PMID- 4138892 TI - [Sequential chemotherapy of inoperable bronchial cancers]. PMID- 4138893 TI - Cellular and humoral response against determinants other than the classical HL-A specificities. Evidence for at least one system independent of the major histocompatibility complex. PMID- 4138894 TI - Cellular immune response to a drug-treated L5178Y lymphoma subline. PMID- 4138896 TI - Capsule production and virulence among strains of Staphylococcus aureus. PMID- 4138895 TI - Stimulation of Herpesvirus saimiri expression in the absence of evidence for type C virus activation in a marmoset lymphoid cell line. AB - Nucleic acid base analogues were used to examine a Herpesvirus saimiri (HVS) infected marmoset lymphoid cell line (MLC-1) for possible association with type C viruses. Synthetic templates poly(rA).d(pT)(10) and poly(dA).d(pT)(10) were used to detect RNA-directed DNA polymerase activity in 100-fold concentrated tissue culture fluids. HVS was monitored by immunofluorescence for early, late, and membrane antigens. MLC-1 cells were exposed to 30 mug of 5-bromo-2'-deoxyuridine (BUdR) per ml for 24 h and examined daily. Similar experiments used 5-iodo-2' deoxyuridine (IUdR) (20 mug/ml) for 30 h or IUdR (20 mug/ml) for 3 days followed by 2% dimethyl sulfoxide for 4 days. Results of these experiments failed to show any type C virus-like polymerase; however, HVS expression was greatly stimulated. BUdR and IUdR enhanced expression of HVS-associated antigens five- to sevenfold, with maximal stimulation being observed 3 to 4 days after removal of the analogue. IUdR-dimethyl sulfoxide treatment was generally less effective. Although more cells showed HVS antigens, the treatments did not increase cell free infectious virus. The data suggest that HVS-infected lymphoid cells can be stimulated to express virus in a manner similar to that of the Epstein-Barr virus in Burkitt's lymphoma cells. No evidence of type C virus was found in stimulated cultures. PMID- 4138897 TI - The ultrastructure of calf heart conducting fibers with special reference to nexuses and their distribution. PMID- 4138898 TI - The ultrastructure of lipid-depleted rod photoreceptor membranes. AB - The structure of lipid-depleted retinal rod photoreceptor membranes was studied by means of electron microscopy. Aldehyde-fixed retinas were exhaustively extracted with acetone, chloroform-methanol, and acidified chloroform-methanol. The effect of prefixation on the extractability of lipids was evaluated by means of thin-layer chromatography and fatty acid analysis. Prefixation with glutaraldehyde rendered 38% of the phospholipids unextractable, while only 7% were unextractable after formaldehyde fixation. Embedding the retina in a lipid retaining, polymerizable glutaraldehyde-urea mixture allows a comparison of the interaction of OsO(4) with lipid-depleted membranes and rod disk membranes which contain all their lipids. A decrease in electron density and a deterioration of membrane fine structure in lipid-depleted tissue are correlated with the extent of lipid extraction. These observations are indicative of the role of the lipid bilayer in the ultrastructural visualization of membrane structure with OsO(4). Negatively stained thin sections of extracted tissue reveal substructures in the lipid-depleted rod membranes. These substructures are probably the opsin molecules which are the major protein component of retinal rod photoreceptor membranes. PMID- 4138899 TI - [Results of cryotherapy in prostatic hypertrophy]. PMID- 4138900 TI - [Pedunculated fibrolipoma of the left tonsil (author's transl)]. PMID- 4138901 TI - [Immunologic evaluation of enriched cell fractions isolated from rat brain]. PMID- 4138902 TI - [Immunological prevention of iso-sensitization to Rh factor. Case studies]. PMID- 4138903 TI - [Immunology of cancer: basic experiments and clinical progress (author's transl)]. PMID- 4138904 TI - Arthur Henry Douthwaite. PMID- 4138906 TI - The use of a radioimmunoassay for alpha-fetoprotein in the diagnosis of malignancy. PMID- 4138905 TI - Failure of low-dose heparin to prevent deep-vein thrombosis after hip-replacement arthroplasty. PMID- 4138908 TI - Diffusion constant and dimension of bacteriophage phi X174 as determined by self beat laser light spectroscopy and electron microscopy. AB - The diffusion constant of bacteriophage phiX174 was determined by laser light self-beat spectroscopy. The method allows one to establish the diffusion constant in comparatively short time and with high accuracy. From the diffusion constant D(37) = 1.96 +/- 0.08 x 10(-7) cm(2)/s, the size of the virus particles within their aqueous milieu can be calculated. For phiX174, a diffusional diameter of 31.4 +/- 1.0 nm was found, in good agreement with measurements of diameters of freezeetched (32.3 +/- 1.8 nm) and negatively stained particles (33.8 +/- 2.1 nm), provided that the entire spikes of the virion are included. Other isometric viruses may show a complex interaction of the virion with the surrounding water and its ions. PMID- 4138907 TI - The use of antinucleoside antibodies to probe the organization of chromosomes denatured by ultraviolet irradiation. PMID- 4138909 TI - An automatic hybrid analyzer of sleep stages in the rat. PMID- 4138910 TI - An autopsy case of Sandhoff's disease. PMID- 4138911 TI - The visualization of concanavalin A binding sites in Purkinje cell somata and dendrites of rat cerebellum. AB - The localization of concanavalin A (Con A) binding sites in Purkinje cell somata and dendrites has been studied using a peroxidase labeling technique. In the somata, the nuclear, Golgi, and endoplasmic reticulum (ER) membranes are rich in Con A binding sites. The hypolemmal cisternae, which are continuous with the ER from the soma and throughout the dendritic tree of Purkinje cells, are also rich in Con A binding sites. Other cisternae seen in these dendrites do not bind detectable amounts of Con A. The results suggest that a cisternal system, rich in carbohydrate, may be continuous from the nuclear envelope to distal dendritic segments of Purkinje cells. Such a system could play a role in the movement of materials from Purkinje somata to dendrites. PMID- 4138912 TI - [In vivo estimation of semen production of rabbits in correlation with ejaculatory spermatic output, testicular size and volumetric proportions of testicular biopsies]. PMID- 4138913 TI - A new adenovirus from sheep. PMID- 4138914 TI - A new method for the quantitative detection of platelet aggregates in patients with arterial insufficiency. PMID- 4138915 TI - 8. Two simple but useful methods for the analysis of dyes: gel-filtration chromatography and solvent extraction. PMID- 4138916 TI - A sex difference in plasma thyroxine and thyroid stimulating hormone in rats. PMID- 4138917 TI - An experimental study of acute neonatal enterocolitis--the importance of breast milk. PMID- 4138918 TI - Study of the cytoplasmic lipids in thymic involution. PMID- 4138919 TI - Early structural changes in a case of late infantile amaurotic idiocy (early form of Batten-Spielmeyer-Vogt disease). PMID- 4138920 TI - X-ray studies on antibody fragments. PMID- 4138922 TI - Ten years experience on prostate cryosurgery. PMID- 4138923 TI - Embryonic antigens in tumor immunity. PMID- 4138921 TI - [Polydeoxynucleotides as DNA models]. PMID- 4138924 TI - Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies. AB - Large percentages of the lymphocytes from some patients with rheumatoid arthritis and systemic lupus erythematosus were densely covered with Ig demonstrable by immunofluorescence, which was occasionally present in the form of caps. The amount and character of the Ig staining depended largely on the procedures used in the isolation and washing of the lymphocytes. Cold-reactive antilymphocyte antibodies present in many sera wre primarily responsible for these variations. Overnight culture of the lymphocytes proved to be an efficient procedure for the removal of adsorbed antibody. Some evidence was also obtained for the presence of circulating immune complexes and exogenous rheumatoid factor molecules on the lymphocyte surface. Thus on freshly isolated cells the demonstration of surface Ig proved to an unreliable marker of bone marrow-derived (B) cells in these disease: the actual percent of B cells with intrinsic surface Ig was often markedly decreased. In patients with systemic lupus erythematosus, this reduction was in agreement with the low numbers of cells that had a receptor for aggregated IgG. The mean percentage of thymus-derived (T) cells in both diseases was slightly greater than the normal level.The concentrations of lymphocytes in joint fluids from patients with rheumatoid arthritis were often greater than levels found in blood. T cells primarily accounted for this increase. The T cells typically formed unusually dense rosettes with sheep erythrocytes. B lymphocytes were proportionally much diminished. Evidence was obtained for the existence of a major joint fluid lymphocyte population that lacked all assayed surface markers. PMID- 4138925 TI - Schizophrenia and the limbic system. PMID- 4138926 TI - Tye B virus and human breast cancer. PMID- 4138927 TI - The CLARA hematoxylin reaction. PMID- 4138928 TI - [4. Degrees of purity and contamination in commercial dyes. Disturbing influence on histological and histochemical dye procedures]. PMID- 4138929 TI - The Ea-2 (H-14) cellular antigen system in the mouse. PMID- 4138930 TI - New Giemsa method for the differential staining of sister chromatids. PMID- 4138931 TI - [9. Problems of column chromatographic and thin layer chromatographic purification of dyes, demonstrated in the example of brilliant cresyl blue]. PMID- 4138932 TI - An ATPase from dog gastric mucosa: changes of outer pH in suspensions of membrane vesicles accompanying ATP hydrolysis. PMID- 4138933 TI - S-100 protein in synapses of the central nervous system. PMID- 4138934 TI - [Is 2,6-dichlorophenolindophenol a specific inhibitor of catalase?]. PMID- 4138935 TI - [The nitroblue tetrazolium test in liver amebiasis in children]. PMID- 4138936 TI - [Alpha-1-fetoprotein in pediatric oncology]. PMID- 4138937 TI - Cytodiagnostic use of Feulgen-DNA measurements in cell imprints from the skin of patients with mycosis fungoides. PMID- 4138938 TI - Temperature-dependent properties of gramicidin A channels. PMID- 4138939 TI - High resolution negative staining of ferritin molecules on vermiculite single crystal supports. PMID- 4138940 TI - Nitrocellulose filter retention method for studying drug-nucleic acid interactions. PMID- 4138941 TI - [Changes in the bone marrow cell count of mice under the combined action of ultrahigh-frequency irradiation and of antitumor preparations]. PMID- 4138942 TI - Erythroid colony formation in vitro by dimethylsulfoxide-treated erythroleukemic cells. PMID- 4138943 TI - Methemoglobin reductase (cytochrome b5 reductase) deficiency in congenital methemoglobinemia. PMID- 4138944 TI - [Importance of the peroxidase determination in acute myeloblastic leukemia]. PMID- 4138945 TI - [Dependence on the menstrual cycle of the number of circulating human blood mast cells (blood basophils). A contribution to the determination of the ovulation time]. PMID- 4138946 TI - Immunochemical identification and characteristics of a specific antigen of the human retina. PMID- 4138947 TI - In vivo tests of thyroid function. PMID- 4138948 TI - Letter: Tests of thyroid function. PMID- 4138949 TI - Surface structures of the gonococcus. PMID- 4138950 TI - Tonsillar gonorrhoea demonstrated by a suction device. PMID- 4138951 TI - Alfred Francois Donne, 1801-1878, discoverer of Trichomonas vaginalis and of leukaemia. PMID- 4138952 TI - The pathogenesis of Hyostrongylus rubidus in growing pigs. PMID- 4138953 TI - Topography of retinal efferent connections in sciurids. PMID- 4138954 TI - Retrograde transport of horseradish peroxidase in transected axons. 1. Time relationships between transport and induction of chromatolysis. PMID- 4138955 TI - [Clinical aspects, therapy and prognosis of colonic carcinoma]. PMID- 4138956 TI - [Ultrastructure and histochemistry of the follicles and follicular cells of the rat adenohypophysis in organotypic culture]. PMID- 4138957 TI - [Histophysical detection of tissular polyanions by bathochromic metachromasia of pseudo-isocyanin]. PMID- 4138958 TI - [Histological basophilia and bathochromic metachromasia of pseudoisocyanin]. PMID- 4138959 TI - [Effects of distilled water aerosols and automobile exhaust gas condensate aerosols on various physiological parameters of rats and of SPF mice]. PMID- 4138960 TI - Transport of succinate in Escherichia coli. III. Biochemical and genetic studies of the mechanism of transport in membrane vesicles. PMID- 4138961 TI - Constitutive heterochromatin of Indian muntjac chromosomes revealed by DNAse treatment and a C-banding technique. PMID- 4138962 TI - Specific C band patterns in continuous human lymphoblastoid cell lines. PMID- 4138963 TI - A study of prostaglandins and prostaglandin antagonists in relation to anaphylaxis in calves. PMID- 4138964 TI - Response of alpha-fetoprotein to chemotherapy in patients with hepatomas. PMID- 4138965 TI - Alpha-fetoprotein and germ cell tumors: a possible role of yolk sac tumor in production of alpha-fetoprotein. PMID- 4138966 TI - Comparison of 5-azacytidine (NSC-102816) with CCNU (NSC-79037) in the treatment of patients with breast cancer and evaluation of the subsequent use of cyclophosphamide (NSC-26271). PMID- 4138967 TI - Failure of indium 111-labeled bleomycin tumor scanning to predict response to bleomycin (NSC-125066) treatment. PMID- 4138968 TI - Treatment of experimental mammary adenocarcinoma with herbicides. PMID- 4138969 TI - Potentiation of bleomycin by an antifungal polyene, pentamycin, in transformed animal cells. PMID- 4138970 TI - Bleomycin-induced damage in prematurely condensed chromosomes and its relationship to cell cycle progression in CHO cells. PMID- 4138971 TI - [Immunochemical studies on two polysaccharides extracted from Salmonella johannesburg 5.58 wild strain and Salmonella johannesburg 5.58 transformed by phage phi 1 (40)]. PMID- 4138972 TI - Characterization of a yeast D-mannan with an alpha-D-glucosyl phosphate residue as an important immunochemical determinant. PMID- 4138973 TI - Monoaminergic tracts of the diencephalon and innervation of the pars intermedia in Rana temporaria. A fluorescence and microspectrofluorimetric study. PMID- 4138974 TI - The effect of change of background colour on the ultrastructure of the pars intermedia of the pituitary of the eel (Anguilla anguilla). PMID- 4138975 TI - Ultrastructural changes of the oenocytes of Gryllus bimaculatus DEG (Saltatoria, Insecta) during the moulting cycle. PMID- 4138976 TI - Specific apocrine secretion in the anterior lobe of the prostate gland of rabbits. PMID- 4138977 TI - Structure of synthetic and native myosin filaments from Amoeba proteus. PMID- 4138978 TI - Some observations on the ultrastructure of the central amygdaloid nucleus in the cat. PMID- 4138979 TI - Hypothalamic projections to the amygdala in the cat. A light and electron microscopic study. PMID- 4138980 TI - [Problem of scabies]. PMID- 4138981 TI - [Stomach carcinoid with atypical course]. PMID- 4138982 TI - [Liver changes in experimental burns]. PMID- 4138983 TI - [Problems in Fridex poisoning]. PMID- 4138984 TI - [Use of gamma-globulins in the treatment of meta-herpetic keratitis (apropos of 3 cases)]. PMID- 4138985 TI - Characterization of anti-heart mitochondria autoantibodies produced in dogs following myocardial infarction. PMID- 4138986 TI - Demonstration of re-entry within the His-Purkinje system in man. PMID- 4138987 TI - The pathophysiology of malignant ventricular arrhythmias during acute myocardial ischemia. PMID- 4138988 TI - The in vivo effect of theophylline on histamine release from human leucocytes. PMID- 4138989 TI - DDT, dieldrin, and heptachlor epoxide in humans with liver cirrhosis. PMID- 4138990 TI - The radioimmunoassay of thyroxine in unextracted human serum. PMID- 4138991 TI - Pattern of Y-chromatin fluorescence in an XYY man. PMID- 4138992 TI - Y-chromatin fluorescence in human buccal smear. PMID- 4138993 TI - Longer Y chromosome in criminals. PMID- 4138994 TI - [Clinical studies on the use of a new combination of substances with antirheumatic action in the treatment of osteo-articular painful syndromes]. PMID- 4138995 TI - [Clearing and anti-platelet-aggregation effects of a heparinoid of natural origin]. PMID- 4138996 TI - Enterohepatic cycling of thyroxine in starved and fed brook trout, Salvelinus fontinalis (Mitchill). PMID- 4138997 TI - DNA helical content during the C-banding procedure. PMID- 4138998 TI - Relative activation and inactivation phenomena between homologous and nonhomologous nucleolus organizers on the normal human G chromosomes. PMID- 4138999 TI - Karyotypic analysis of a near-diploid established mouse cell line. PMID- 4139000 TI - A (6;21) translocation, unbalanced, 46 chromosomes. Repository identification no. GM-144. PMID- 4139001 TI - An (X;1) translocation, balanced, 46 chromosomes. Repository identification no. GM-97. PMID- 4139002 TI - Treatment of pulmonary tuberculosis. PMID- 4139004 TI - His bundle parasystole: A form of A-V junctional parasystole. PMID- 4139003 TI - Simultaneous cure of thyrotoxicosis and Wolff-Parkinson-White syndrome. PMID- 4139005 TI - Chromosome regions containing DNAs of known base composition, specifically evidenced by 2,7-di-t-butyl proflavine. Comparison with the Q-banding and relation to dye-DNA interactions. PMID- 4139007 TI - [Teaching for a human future from learning from animals]. PMID- 4139006 TI - Location of repetitious DNA in the chromosomes of the desert locust (Schistocerca gregaria). PMID- 4139008 TI - [The effects of oral contraceptives on male-pattern alopecia, seborrhoea, acne vulgaris and hirsutism. Anamnestic study on 325 women]. PMID- 4139009 TI - [Immunodiagnostics of neoplasms]. PMID- 4139010 TI - [Drug induced hematologic changes]. PMID- 4139012 TI - Examinations of the gomori-positive cells of the thymus in tissue culture. PMID- 4139011 TI - [Desquamative gingivitis. A case report]. PMID- 4139013 TI - Life stage and secretory cycle of anterior pituitary basophils. PMID- 4139015 TI - CSF-protein patterns in extrapyramidal diseases. Preliminary report with special reference to the protein patterns in Huntington's chorea. PMID- 4139014 TI - Relation between syringomyelia and von Hippel-Lindau's disease. PMID- 4139016 TI - A new metabolic disorder: myopathy with glycosamino(sialo)glycans accumulation. PMID- 4139017 TI - The uptake, distribution and anti-tumor activity of bleomycin in gliomas in the mouse. PMID- 4139018 TI - Sinus histiocytosis with massive lymphadenopathy--properties of cultured histiocytes. PMID- 4139019 TI - Effect of bleomycin on the sheep erythrocyte-induced rossette formation and on the allograft survival in mice. PMID- 4139020 TI - The preparation and purification of HL-A monospecific antigens using platelets and various lymphoid sources. PMID- 4139021 TI - Papain-resistant (f) and papain-sensitive (g) subclasses of rabbit sLgA. Allotypic specificities on different domains of the g subclass of alpha-chains (alpha g). PMID- 4139022 TI - Localization and structural features of an antigenic determinant in sea anemone collagen. PMID- 4139023 TI - The generation of antibody diversity. II. Plaque morphology as a simple marker for antibody specificity at the single-cell level. PMID- 4139024 TI - Immunogenicity and antigenic specificity of the loop fragment of lysozyme. PMID- 4139025 TI - Modification of culture medium for Xenopus embryonic cells. I. Effects of albumin and other proteins. PMID- 4139026 TI - Association of antibody to nerve growth factor with ganglionic non-neurons (glia) and consequent interference with their neuron-supportive action. PMID- 4139027 TI - The nuclear DNA content and chromatin ultrastructure of the coelacanth Latimeria chalumnae. PMID- 4139029 TI - [Effects of pH on the staining of human chromosomes with acridine orange]. PMID- 4139028 TI - Reactivation of nuclear RNA polymerase activity in growth stimulated epithelial cells. PMID- 4139030 TI - Rapid techniques for counting and analysis of chromosome aberrations. PMID- 4139031 TI - Ocular antigens. V: Species specificity of structural glycoproteins isolated from ocular connective tissues. An immunofluorescence and immunochemical study. PMID- 4139032 TI - Ocular antigens. VI: Immunogenic determinants in ocular and non-ocular tissues related to uveal pigment granules. An immunofluorescence and immunodiffusion study. PMID- 4139033 TI - The presence of a polyadenylic acid-dependent DNA polymerase in calf lens. PMID- 4139034 TI - Numerical increase of Gomori-positive glia in rat optic nerve following x irradiation. PMID- 4139035 TI - [Thalamic projections of the vestibular nuclei: a histological study in the cat (author's transl)]. PMID- 4139036 TI - Role of nerve-muscle contact in maintaining synaptic connections. PMID- 4139037 TI - Selective degeneration of central dopaminergic systems after injection of 6 hydroxydopamine in the ventral mesencephalic tegmentum of the rat. Demonstration by the Fink-Heimer strain. PMID- 4139039 TI - Unusual lysosomes in hamster hepatocytes. PMID- 4139038 TI - Schistosoma mansoni: defined system for stepwise transformation of cercaria to schistosomule in vitro. PMID- 4139040 TI - Retrograde axoplasmic transport: its continuation as anterograde transport. PMID- 4139041 TI - Reaction mechanisms in the release of mediators of immediate hypersensitivity from human lung tissue. PMID- 4139042 TI - Novel inhibitors of RNA synthesis. PMID- 4139043 TI - Chemistry and mechanism of action of bleomycin. PMID- 4139044 TI - [Clinical and laboratory data supporting the possible relationship between dental foci and erythema exudativum multiforme]. PMID- 4139045 TI - Effect of anti-sperm antibodies on oxygen utilization and lactic acid production by human spermatozoa. PMID- 4139046 TI - Energy dispersive x-ray analysis: application to assessment of spermatoan viability in primate semen. PMID- 4139047 TI - [Incidence and intensity of uterine bleeding in the neonate (author's transl)]. PMID- 4139048 TI - Determination by radioimmunoassay of the luteinising hormone-releasing hormone (LHRH) content of the hypothalamus of the rat and some lower vertebrates. PMID- 4139049 TI - Systemic lupus erythematosus and lupus renal disease. Diagnosis and management. PMID- 4139051 TI - [Determination of gestational age by means of Nil-blue staining of an amniotic fluid sample]. PMID- 4139050 TI - [Immunological aspects of pregnancy]. PMID- 4139052 TI - [The importance of immune enzyme technics in immunological diagnosis]. PMID- 4139053 TI - [Quantification of granulocyte protection in hemoblastoses]. PMID- 4139054 TI - [Counting of leukocytes effective for the prevention of infection in leukemias by counting leukocytes in the saliva]. PMID- 4139055 TI - [Autoimmune reactions in the area of leukocytes with special reference to drug induced forms]. PMID- 4139056 TI - [The serological usefulness of deep-frozen lymphocytes in the cell panel]. PMID- 4139057 TI - [Hemolytic anemias induced by drug hypersensitivity]. PMID- 4139058 TI - [Qualitative and quantitative criteria in cytological bone marrow diagnosis]. PMID- 4139059 TI - [New studies in the realm of the HL-A system: a 3d locus with serologically demonstrable markers]. PMID- 4139060 TI - [The value of proof in paternity exclusions in the HL-A system]. PMID- 4139061 TI - Quantitative determination of aggregated IgG in gamma globulin preparations. PMID- 4139062 TI - [Blood coagulation and fibrinolysis in premature and mature infants with respiratory distress syndrome and intracranial hemorrhage]. PMID- 4139063 TI - [Comparative studies on platelet kinetics using various stabilizers]. PMID- 4139064 TI - [Results of various sedimentation procedures for the production of leukocyte-poor human erythrocyte concentrates]. PMID- 4139065 TI - [Cryoprecipitates. 3. Concentration of plasma constituents in cryoprecipitates and their meaning for clinical practice]. PMID- 4139066 TI - [Standardization proposal for the serology of the bed side test]. PMID- 4139067 TI - [Results of the accumulation and electron-optical presentation of Australia antigen]. PMID- 4139068 TI - The effect of phenformin plus stanozolol on fibrinolysis, platelet adhesiveness and blood lipids in patients with recurrent venous thrombosis. PMID- 4139069 TI - [Acute transitory variants of autoimmune hemolytic anemias]. PMID- 4139070 TI - [Immunofluorescence patterns on cell membranes of human lymphocytes]. PMID- 4139071 TI - Monocytic and lymphocytic origin of macrophages (preliminary communication). PMID- 4139072 TI - Improvement in the cytochemical localization of aryl sulphatase in bone marrow and blood cells by use of naphtyl-sulphate and naphtol-AS-BI-sulphate. PMID- 4139073 TI - [Immunomorphological studies on lymphocytes in drug allergies]. PMID- 4139074 TI - Platelet functions and ultrastructure in the Hermansky-Pudlak syndrome. PMID- 4139075 TI - Structure and function of peripheral blood leukocytes from patients with elevated steroid level in organism. I. Electron microscopic and cytochemical studies of leukocytes of peripheral blood in Cushing's syndrome. PMID- 4139076 TI - Human CGL bone marrow cells grown in vitro, their immunological, cytological and cytochemical characteristics and attempts of their xenotransplantation. PMID- 4139077 TI - [Changes in the lung in lymphogranulomatosis and the results of cytostatic treatment]. PMID- 4139078 TI - [Complications in polycythemia rubra vera and its occurrence in other diseases]. PMID- 4139079 TI - [Monoclonal gammopathies]. PMID- 4139080 TI - [Considerations on HL-A antigens and their isolation]. PMID- 4139081 TI - [HL-A antibodies in polytransfused patients]. PMID- 4139082 TI - [The effect of leukocyte and thrombocyte antibodies in anti-thymocyte globulin (ATG) on the organism]. PMID- 4139083 TI - [Comparative study of the screening methods used for histocompatibility testing, electrophoretic precipitation and latex test]. PMID- 4139084 TI - [Serological character of the modifications of platelet antigens in malignant tumors]. PMID- 4139085 TI - Thrombohaemorrhagic skin lesion induced by a single injection of neuraminidase (EC. 3.2.1.18) in rabbits. PMID- 4139086 TI - The tissue plasminogen activator and plasma fibrinolysis in diet induced lipemia in rats. PMID- 4139087 TI - [Hemophilic pseudotumor in the calcaneus]. PMID- 4139088 TI - [Report on 2 further families with occurrence of Bu-a-1]. PMID- 4139089 TI - [Cryoprecipitates. 4. Antigenic properties of cryoprecipitates]. PMID- 4139090 TI - [Serological quality requirements for cryoprecipitates]. PMID- 4139091 TI - Applications of the fluorescence technique of Falck-Hillarp in studies on connections in the central nervous system. PMID- 4139092 TI - Formation of messenger RNA in animal cells. PMID- 4139093 TI - 14S mRNA of immunoglobulin light chain: purification, translation, and transcription into cDNA. PMID- 4139094 TI - Binding of a phallotoxin to protein filaments of plasma membrane of liver cell. PMID- 4139095 TI - Family therapy training: a statewide program for mental health centers. PMID- 4139096 TI - Different forms of incomplete trisomy 13. Mosaicism and partial trisomy for the proxim. PMID- 4139097 TI - G-band analyses of an established cell line of a human malignant glioma. PMID- 4139098 TI - Pericentric inversion of "fluorescent" segment in chromosome no. 3. PMID- 4139099 TI - Subdivision of the human Y chromosome. PMID- 4139100 TI - Studies on the mechanism of chromosome banding with trypsin. PMID- 4139101 TI - Serum polymorphisms in Down's syndrome. PMID- 4139102 TI - [Analysis of the linkage between the HL-A loci and the genes of other markers (author's transl)]. PMID- 4139103 TI - Inherited (13;14) translocation and reproduction. Report on three families. PMID- 4139104 TI - Comparison of glycoproteins isolated by phenol-water partition of human erythrocyte membranes. PMID- 4139105 TI - Linear and nonlinear HL-A9 subdivisions generated by serial dilution. PMID- 4139106 TI - Platelet aggregation as a quantitative immunologic technique. PMID- 4139107 TI - Activity of mouse reaginic antibodies in the rat: passive cutaneous anaphylaxis and in vitro passive histamine release. PMID- 4139108 TI - Contact sensitivity to oxazolone in the mouse. VIII. Demonstration of several classes of antibody in the sera of contact sensitized and unimmunized mice by a simplified antiglobulin assay. PMID- 4139109 TI - Photometric evaluation of indirect immunofluorescence chessboard titrations for the characterization of FITC-labelled antibodies. PMID- 4139110 TI - The optical rotatory dispersion of antigen-antibody complexes. PMID- 4139111 TI - A physiological mechanism preventing experimental allergic encephalitis. PMID- 4139112 TI - Effect of non-ionic polymers on the formation of immuno-precipitates in single radial immunodiffusion techniques. PMID- 4139113 TI - Hydrational aspects of A-anti-A and B-anti-B interactions. PMID- 4139114 TI - Polymorphism and intraspecific differences among spermatozoan and seminal plasma antigens. PMID- 4139115 TI - Subtypes of hepatitis B antigen. PMID- 4139116 TI - Effects of antigen-antibody complexes on the primary immune response in Rhesus monkeys. AB - A model for the enhancement of the primary humoral immune response of rhesus monkeys to marginal or weakly antigenic vaccines is presented. Our procedure used the complexing of formalin-inactivated Venezuelan equine encephalomyelitis (VEE) virus vaccine with specific, homologous, immune gamma globulin (IgG) at equivalence. Equivalence was determined by combining the concentrated, isotopically labeled ((3)H) virus with various concentrations of specific Sephadex-fractionated IgG. Enhancement of VEE virus antibody response in monkeys was obtained from preparations containing a marginal concentration of antigen that was complexed at equivalence with homologous IgG as compared with antigen alone. Protection in Swiss mice closely paralleled the antibody response pattern observed in monkeys, since complexes at equivalence provided 30 to 50% greater protection against challenge than antigen alone. PMID- 4139118 TI - Measurement of intracellular iodophilic polysaccharide in two cariogenic strains of Streptococcus mutans by cytochemical and chemical methods. AB - Quantitative cytological and chemical methods have been developed to study the intracellular iodophilic polysaccharide (IPS) content of two strains of Streptococcus mutans. The cytological method uses a periodic acid-chlorite treatment of thin sections to increase the affinity of IPS for uranyl and lead salts. This results in the IPS appearing as individual electron-dense granules which can be counted for quantitative studies. As a basis for these quantitative studies, IPS was measured chemically by dissolving whole cells with hot KOH and quantitating spectrophotometrically the amount of iodine-polysaccharide complex formed. PMID- 4139117 TI - Effect of synthetic disaccharide-protein conjugate as an immunogen in Salmonella infection in mice. AB - The synthetic disaccharide 3-O-alpha-tyvelopyranosyl-alpha-D-mannopyranoside, identical to the O antigen 9 determinant in Salmonella, covalently linked to bovine serum albumin and suspended in Freund complete adjuvant, was used as an immunogen in mice. Antibodies in high titer were formed against the O9 determinant as estimated by a bactericidal assay, whereas only low titers of hemagglutinating antibodies were found. A sensitive in vivo assay demonstrated that in immunized mice, after challenge with two strains of equal virulence but with different O antigens (O9, 12 and O4, 5, 12, respectively), the growth of the strain with the O9 determinant was suppressed in comparison to that with the O4 determinant. PMID- 4139119 TI - Antigenic relationships among Newcastle disease virus mutants obtained from laboratory strains and from recent California isolates. AB - The antigenic relationship between pairs of plaque mutants of Newcastle disease virus (NDV) derived from laboratory strains and from isolates from the 1971-72 California epizootic were examined by kinetic neutralization test. Comparing four sets of mutants from laboratory strains by both kinetic neutralization and hemagglutination inhibition tests, a similarity was found in the antigenic relationship expressed as an r value with both tests. However, kinetic neutralization was the more precise as well as sensitive assay. Antigenic diversity was greatest between pairs of mutants from different strains, but distinctions could also be made between mutants from the same strains such as Herts-L and Herts-S with an r value of 36%. Examination of mutants from the California epizootic isolated from separate locations and at different times showed antigenic divergence which was greatest between two red-plaque mutants with an r value of 39%. Antigenic distinctions were found between a red- and clear-plaque mutant obtained from isolates taken from brain and tracheal swabs of one infected chicken. In addition to antigenic divergence found between pairs of some mutants, two of the clear-plaque mutants reacted more avidly with antibody than did the corresponding red-plaque partner. Thus, both differences in antigenicity and avidity can be found among these NDV mutants. The antigenic variation found among these mutants is similar to that found within a serotype. This would imply that at the present NDV is a single serological type. PMID- 4139120 TI - New type of exfoliatin obtained from staphylococcal strains, belonging to phage groups other than group II, isolated from patients with impetigo and Ritter's disease. AB - Four strains of Staphylococcus aureus of a phage type other than the second group, isolated from patients with impetigo and Ritter's disease, were found to produce an exotoxin similar to those reported by Melish et al. (1972), Kapral and Miller (1971), and Arbuthnott et al. (1973). This toxin could elicit a general exfoliation of the epidermis with the so-called Nikolsky sign when subcutaneously inoculated into neonatal mice within 4 days after birth. The new toxin was serologically different from exfoliatin produced by the phage group II staphylococci previously reported (Kondo et al., 1973) and showed an electrophoretic pattern corresponding to that of the B-type toxin of the latter in acrylamide disc electrophoresis. It had the same molecular weight as that of the latter, which was estimated to be about 24,000. It was thermolabile and lost its toxic activity by heating at 60 C for 30 min; in addition, most of the toxicity was lost within 1 month of storage even at -30 C. We propose to designate the old typical heat-stable exfoliatin as S. aureus exfoliatin A and the new heat-susceptible exfoliatin as S. aureus exfoliatin B. PMID- 4139121 TI - Ultrastructure of pili and annular structures on the cell wall surface of Neisseria meningitidis. AB - In a survey of negatively stained preparations of the prototype strains of Neisseria meningitidis, pili were detected on three strains. However, these pili were detected on fewer than 5% of cells in populations of these three strains. Those individual cells with pili were seldom observed to contain more than two or three pili per cell. In contrast, nearly all cells of the nonprototype group B strain ATCC 13090 had numerous pili on their surfaces. When viewed in frozen etched replicas, a few pili were observed lying on the cell surface of this latter strain. An annular structure was also found in frozen-etched replicas. This structure usually consisted of a series of concentric rings that were always found on the flat side of these bean-shaped cells. It is concluded that such structures represent a differentiated portion of the cell wall, which is involved in cross-wall formation during synthesis of the cell septum in dividing cells. PMID- 4139122 TI - Comparison of the chemical structure and biological activities of the glycolipids of Salmonella minnesota R595 and Salmonella typhimurium SL1102. AB - It has been assumed in the past that the lipid moieties of endotoxic lipopolysaccharides are quite similar if not identical. This has been tested in the reported work here, where the chemical composition and biological activities of the glycolipids of two heptoseless Re mutants, Salmonella minnesota R595 and Salmonella typhimurium SL1102, have been studied and compared. The two glycolipids, extracted with chloroform-methanol (4:1), showed identical thin layer chromatographic patterns. The molar ratios for hexosamine, fatty acids, phosphorus, 2-keto-3-deoxyoctonate, total amines, and total nitrogen of the purified glycolipids were in the same range, but small differences could be established. Both glycolipids contained the same major fatty acids, i.e., lauric, myristic, palmitic, and 3-hydroxymyristic acids, in similar but not identical ratios. On paper electrophoresis, the acid hydrolysates of the two glycolipids showed analogous components. In the determination of molecular weight, whereas S. minnesota R595 glycolipid did not show concentration dependence, the molecular weight measured for S. typhimurium SL1102 increased with its concentration. The molecular weight of the fully endotoxic R595 glycolipid has been found to be 17,000 +/- 1,500. Both glycolipids showed similar activities in the Shwartzman skin reaction, Limulus-lysate clotting assay, mouse lethality, and enhancement of nonspecific resistance, but the R595 preparation appeared to be more active on a weight basis in some parameters than SL1102. Using passive hemagglutination, we observed cross-reactivity between the glycolipids. In the gel-diffusion test, they revealed clear identity. The antiserum against S. minnesota R595 neutralized the Shwartzman skin reactivity not only of R595 but also of SL1102 glycolipid. These results confirm that there are identical immunodeterminant group(s) in the two glycolipids. On the other hand, chemical analytical data for two glycolipids showed only similarities, indicating that although both glycolipids are of comparable chemical nature, differences between them exist. PMID- 4139123 TI - Correlation between in vitro anaphylactic histamine release from tissues and reagin titer in rat. PMID- 4139124 TI - Ultraviolet light absorption and fluorescence properties of an allergen extracted from Ascaris suum. PMID- 4139125 TI - A search for markers of rabbit lymphoid cells; alloantigens characterized by antisera to rabbit thymus. PMID- 4139126 TI - Gastric fetal sulphoglycoprotein antigen (FSA) and blood group antigens A and B. PMID- 4139127 TI - Effect of divalent cations and metabolic energy on the anaphylactic histamine release from rat peritoneal mast cells. PMID- 4139128 TI - In vitro studies of concanavalin-A-induced histamine release from human basophils: excess bridging in the inhibitory region of the dose-response curve. PMID- 4139129 TI - Adjuvant activity for alkylamines of immune responses to ovalbumin, myelin basic protein and a tumor. PMID- 4139131 TI - Immune basophil degranulation: detection by iodonitrotetrazolium dehydrogenase stain. PMID- 4139130 TI - The inhibitory effect of nicotinamide on asthma-like symptoms and eosinophilia in guinea pigs, anaphylactic mast cell degranulation in mice, and histamine release from rat isolated peritoneal mast cells by compound 48-80. PMID- 4139132 TI - Populations of guinea pig lymphocytes and Kurloff cells characterised by rosette forming reactions. PMID- 4139133 TI - ATP level and CO2 production of mast cells in anaphylaxis. PMID- 4139134 TI - Studies on the cytotoxic immune reaction. IV. Occurrence and specificity of metabolically dependent cell surface antigens in various animal tissues. PMID- 4139135 TI - Macro- and microdifferences in blood group antigens and antibodies. II. Subgroups of A, an example of graded microdifferences. PMID- 4139136 TI - Fine structure of Muller cells in the human retina as revealed by ruthenium red treatment. PMID- 4139137 TI - Interreceptoral junctions in the teleost retina. PMID- 4139138 TI - Nitroblue-tetrazolium (NBT) reduction in leukocytes of children with acute leukemia. PMID- 4139139 TI - [Rumination as a psychophysiologic disorder in early childhood]. PMID- 4139140 TI - [Recurrent idiopathic hematuria in children]. PMID- 4139141 TI - Quantitation of DNA by cytofluorometry of the conventional Feulgen reaction. PMID- 4139142 TI - The 'chess board' distribution of glycogen in liver. Artifact of fixation or the effect of an enzyme? PMID- 4139143 TI - The effects of age and exercise on the succinic dehydrogenase content of dystrophic hamster muscle fibres. PMID- 4139144 TI - The histochemical demonstration of mucosubstances in the glandular layer of the spermoviduct of the slug Deroceras laevis. PMID- 4139145 TI - Some histochemical observations on the mucosubstances of the nasal glands of the mouse. PMID- 4139146 TI - Studies on the alkaline hydrolysis of nucleic acid in tissue sections. V. Cytophotometric evaluation of the effect of an alkaline hydrolysis on the Feulgen reaction. PMID- 4139147 TI - Cholinesterase-rich cells in the rat fundic mucosa. A light and electron microscopical investigation. PMID- 4139149 TI - Acridine orange as a supravital fluorochrome indicating varying degrees of chromatin condensation. PMID- 4139148 TI - Investigation of staining, polarization and fluorescence microscopic properties of myoepithelial cells. PMID- 4139150 TI - Immunoperoxidase and immunofluorescence techniques in pig tissues. PMID- 4139152 TI - Some evidence of the nature of the Golgi-Cox deposit and its biochemical origin. PMID- 4139151 TI - Semipermeable membranes for improving the histochemical demonstration of enzyme activities in tissue sections. IV. Glucose 6-phosphate dehydrogenase and 6 phosphogluconate dehydrogenase (decarboxylating). PMID- 4139153 TI - Cardiovascular effects of the addition of N2O to halothane in stump-tailed macaques during spontaneous and controlled ventilation. PMID- 4139154 TI - Carbon monoxide euthanasia of dogs: chamber concentrations and comparative effects of automobile engine exhaust and carbon monoxide from a cylinder. PMID- 4139157 TI - Confirmation of six organothiophosphorus pesticides by chemical derivatization at nanogram levels. PMID- 4139156 TI - Confirmation of pesticide residue identity. VIII. Organophosphorus pesticides. PMID- 4139155 TI - Comparison of pituitary gland cytology in three species of leaf-nosed bat (Hipposideridae). PMID- 4139158 TI - Radioimmunoassay for phenobarbital. PMID- 4139159 TI - Adsorption of proteins onto hydrophobic polymer surfaces: adsorption isotherms and kinetics. PMID- 4139160 TI - Ultrastructural localization of rhodopsin in the vertebrate retina. AB - Early work by Dewey and collaborators has shown the distribution of rhodopsin in the frog retina. We have repeated these experiments on cow and mouse eyes using antibodies specific to rhodopsin alone. Bovine rhodopsin in emulphogene was purified on an hydroxyapatite column. The purity of this reagent was established by spectrophotometric criteria, by sodium dodecyl sulfate (SDS) gel electrophoresis, and by isoelectric focusing. This rhodopsin was used as an immunoadsorbent to isolate specific antibodies from the antisera of rabbits immunized with bovine rod outer segments solubilized in 2% digitonin. The antibody so prepared was shown by immunoelectrophoresis to be in the IgG class and did not cross-react with lipid extracts of bovine rod outer segments. Papain digested univalent antibodies (Fab) coupled with peroxidase were used to label rhodopsin in formaldehyde-fixed bovine and murine retinas. In addition to the disk membranes, the plasma membrane of the outer segment, the connecting cilium, and part of the rod inner segment membrane were labeled. We observed staining on both sides of the rod outer segment plasma membrane and the disk membrane. Discrepancies were observed between results of immunolabeling experiments and observations of membrane particles seen in freeze-cleaved specimens. Our experiments indicate that the distribution of membrane particles in freeze cleaving experiments reflects the distribution of membrane proteins. Immunolabeling, on the other hand, can introduce several different types of artifact, unless controlled with extreme care. PMID- 4139161 TI - Ultrastructure of mitosis and cytokinesis in the multinucleate green alga Acrosiphonia. AB - The processes of mitosis and cytokinesis in the multinucleate green alga Acrosiphonia have been examined in the light and electron microscopes. The course of events in division includes thickening of the chloroplast and migration of numerous nuclei and other cytoplasmic incusions to form a band in which mitosis occurs, while other nuclei in the same cell but not in the band do not divide. Centrioles and microtubules are associated with migrated and dividing nuclei but not with nonmigrated, nondividing nuclei. Cytokinesis is accomplished in the region of the band, by means of an annular furrow which is preceded by a hoop of microtubules. No other microtubules are associated with the furrow. Characteristics of nuclear and cell division in Acrosiphonia are compared with those of other multinucleate cells and with those of other green algae. PMID- 4139162 TI - Fine structural demonstration of ordered arrays of cytoplasmic filaments in vertebrate iridophores. A comparative survey. AB - Thin and thick sections of both physiologically active and physiologically passive iridophores from a range of vertebrate species have been examined by electron microscopy at 60 kV and at 1,000 kV. All iridophores studied have been found to contain 65-A filaments linking successive crystals in their parallel stacks; their orientation in the cell is shown in stereo pairs of 0.25-microm sections obtained from high voltage microscopy. In addition, several of the physiologically passive iridophores contain 100-A filaments in varying numbers. It is suggested that the thin filaments might be iridophore actin and play a role in the movement of iridophore components, and that the 100-A filaments might play a cytoskeletal role in the iridophores in which they occur. PMID- 4139163 TI - Effects of phosphotungstate negative staining on the morphology of the isolated Golgi apparatus. AB - Isolated Golgi complexes can be recognized in phosphotungstate (PTA) negative stain as stacks of membranous plates surrounded by a complex anastomosing network of tubules and vesicles. The extent of this tubular network is, however, much greater than can be observed in thin sections of whole cells. To determine which of the steps leading to the final negatively stained image may produce the observed changes, we have monitored each of the steps by other electron microscope and biochemical methods. The first damage to the membranes seems to occur during the initial isolation procedure as judged by the appearance of smooth patches on the freeze-fractured membrane faces that are normally covered with particles. Subsequent suspension of the Golgi fraction in water, to dilute the sucrose for negative staining, leads to the disappearnce of the stacking, to some tubulation and some vesiculation of the membranes as judged by thin section and freeze-cleave microscopy. The latter technique also reveals an increase in smooth-cleaving membrane faces. Application of the negative stain to the water washed Golgi fraction, finally, produces extensive tubular arrays and a simultaneous decrease in the remaining large membranous vesicles. The freeze cleaved tubular membranes appear essentially smooth except for small patches of aggregated particles. Parallel gel electrophoresis studies of the membranes and of the water and negative stain wash extracts indicate that protein extraction is involved in these morphological changes. PTA seems to be a particularly effective solvent for certain membrane proteins that are not removed by the water wash. These observations suggest that removal of membrane proteins alters structural restraints on the membrane lipids so that they behave semiautonomously like myelinics and form new artificial structures. This does not eliminate the possibility, however, that some tubules also exist in the Golgi apparatus in vivo. PMID- 4139164 TI - Characterization of calcium oxalate and calcium phosphate deposits in sarcoplasmic reticulum vesicles. PMID- 4139165 TI - Light and electron microscopy of laser microirradiated chromosomes. PMID- 4139166 TI - Localization of lipophosphonoglycan on both sides of Acanthamoeba plasma membrane. PMID- 4139167 TI - Detection of DNA synthesis in interphase nuclei by fluorescence microscopy. PMID- 4139168 TI - Prognosis and survival with extranodal Hodgkin's disease. PMID- 4139169 TI - Immunologic reactions and Australia antigenemia in Down's syndrome. PMID- 4139170 TI - Plasma renin activity, renin substrate and aldosterone during treatment with various oral contraceptives. PMID- 4139171 TI - Immunologic specificity of transfer factor. AB - This study examined the immunologic specificity of transfer factor using a chromatographically purified transfer factor preparation. The specificity of transfer was examined utilizing immunity to keyhole limpet hemocyanin (KLH) and tuberculin. Transfer factor prepared from a donor immune to KLH successfully transferred KLH skin test reactivity to 10 out of 10 recipients. In contrast, comparable amounts of transfer factor from two donors not immune to KLH failed to transfer immunity to KLH in 11 recipients despite evidence for successful transfer of tuberculin reactivity. Unlike prior studies with a variety of antigens, the immunity to KLH in recipients of KLH immune transfer factor appeared comparable to that of the donor since both could be elicited with the same skin test antigen dose. These observations indicate that transfer factor can initiate a specific immune response to an antigen not previously encountered by the recipient and that in certain circumstances this immune response can be comparable to that of the donor. These observations on specificity and potency of transfer factor have important implications for the clinical use of this material. PMID- 4139172 TI - An immunoperoxidase technique for the identification of gastrin-producing cells. AB - A technique for the identification of gastrin-producing cells (G cells) is described. This is applicable to formalin-fixed, paraffin-embedded material. It is based on an immunohistochemical method using peroxidase-labelled antibodies. PMID- 4139173 TI - Deep scopulariopsosis: a case report and sensitivity studies. AB - A 36-year-old female was admitted to hospital for debridement of chronically inflamed tendon sheaths and adjacent tissues near the left ankle. Despite antibiotic therapy and initial surgical interventions, the inflammation had progressed slowly over 16 months. Histopathological examination of excised tissues in September 1973 revealed a chronic granulomatous inflammation of tendon sheaths and muscle. Many branched hyphal segments, intercalary swollen cells, and a few conidia-like bodies were seen in sections, and also in KOH- and PAS-stained slides prepared from homogenized tissues. Culture of homogenized tissues yielded pure colonies of Scopulariopsis brevicaulis. Sensitivity tests were initially begun with amphotericin B, potassium iodide, and potassium tartrate (0.05-15 mug/ml of the phytone-yeast extract agar), and no inhibitory effect was observed. Subsequently, amphotericin B, antimony, 5-fluorocytosine (5-FC), griseofulvin, hamycin, and mycostatin were tested (25-300 mug/ml of the phytone-yeast extract agar). Of these chemicals, griseofulvin and hamycin proved to be most effective. Antimony and 5-FC were ineffective, and mycostatin produced a negligible effect on growth. The four strains of Lysobacter antibioticus, the producer of myxin antibiotic, strongly inhibited the growth of the fungus. PMID- 4139174 TI - Interaction of gelatin with stereospecific binding proteins and its enhancement of competitive binding assays. AB - The effect of gelatin (0.5 g/l) on binding curves at high dilution of three classes of stereo-specific binding proteins was studied. These included two antibodies (to oestradiol and aldosterone), six transins (horse and dog transcortins, human thyroxine-binding globulin, human sex steroid-binding globulin, and guinea pig transprogestin), and one receptor (bovine adrenal protein kinase). Gelatin increased the apparent binding of all these proteins, particularly at the highest dilutions and sometimes in a striking manner. While much of this action can be attributed to its decreasing the adhesion of the dilute binding protein to glass, gelatin also increased the apparent uptake of some tracers by certain adsorbents. Similar findings were obtained using human gamma globulin (2 g/l). These effects resulted in increased sensitivity and improved reproducibility in the assays employing them. PMID- 4139175 TI - Cultivation of periodontal ligament fibroblasts on dental implant materials and enzymatically debrided teeth. PMID- 4139176 TI - Ultrastructure of the gingival epithelium in the new born cat--some characteristics of the intercellular junctions. PMID- 4139177 TI - Radiophosphorous (P32) treatment in carcinoma of the breast and prostate: report of 39 cases. PMID- 4139178 TI - Robust metal complexes, ferrocenylmethyl carboxyhydrazide and 1 chloromercuriferrocene, as electron-opaque stains for aldehydes and thiol groups. PMID- 4139179 TI - Variability of the shape and argentaffinity of the granules in the enteroendocrine cells of the mouse duodenum. PMID- 4139180 TI - Nucleoside diphosphatase in the onion root tip. I. Effects of fixation and lead on enzyme activity. PMID- 4139181 TI - Procion yellow M-4RS binding to neuronal membranes. PMID- 4139182 TI - Immunofluorescence counterstains. PMID- 4139184 TI - Effects of two chelating agents, oxine and diethyldithiocarbamate (Antabuse), on stainability and motility of human sperms. PMID- 4139183 TI - Quantitative microfluorimetric studies on formaldehyde-induced fluorescence of 5 hydroxytryptamine in the pineal gland of the rat. PMID- 4139185 TI - The histochemical interpretation of the complex results of methylation upon gastrointestinal tract mucins, with special reference to the periodic acid-Schiff reactivity. PMID- 4139186 TI - Letter: Mechanism of tissue component staining by osmium tetroxide. PMID- 4139187 TI - Letter: Detection of luteinizing hormone-releasing hormone in the guinea pig median eminence with an immunohistoenzymatic technique. PMID- 4139188 TI - The ultrastructural localization of cytochrome c-oxidase complex in a lipid retaining, glutaraldehyde-urea embedment. PMID- 4139189 TI - Letter: Positive identification of intracellular biogenic amine reaction product with electron microscopic x-ray analysis. PMID- 4139190 TI - Letter: Diaminobenzidine activity in the platelet dense body. PMID- 4139191 TI - Cold staining methods for mycobacteria. PMID- 4139192 TI - Changes in the lytic spectrum and antigenic properties of mycobacteriophages after passages on Mycobacterium tuberculosis and other mycobacteria. PMID- 4139193 TI - Cellular events in tolerance. III. Carrier tolerance as a model for T cell unresponsiveness. PMID- 4139194 TI - Transplantation of a Marek's disease lymphoma in syngeneic chickens. PMID- 4139195 TI - Further studies on the immunologic relationships among measles, distemper, and rinderpest viruses. PMID- 4139196 TI - Dissociation of T cell helper function and delayed hypersensitivity. PMID- 4139197 TI - Receptors for antigen on lymphoid cells. I. Immunoadsorption of plaque-forming cells to poly-L-lysine-fixed antigen monolayers. PMID- 4139198 TI - The plaque cytogram assay. I. Light and scanning electron microscopy of immunocompetent cells. PMID- 4139199 TI - Peyer's patch lymphocytes: demonstration of the integrity of afferent and efferent T-cell functions in the guinea pig and rat. PMID- 4139200 TI - Adjuvanticity of synthetic polynucleotides for induction of experimental allergic encephalomyelitis in guinea pigs. PMID- 4139201 TI - The antibody response to myelin basic protein in Lewis and Fischer rats as followed by a sodium sulfate method of radioimmunoassay. PMID- 4139202 TI - The antibody response to myelin basic protein (BP) in Lewis rats: the effect of time, dosage of BP, and dosage of Mycobacterium butyricum. PMID- 4139203 TI - The effect of measles virus infection on T and B lymphocytes in the mouse. I. Suppression of helper cell activity. PMID- 4139204 TI - In vivo and in vitro production of a slow reacting substance in the rat upon treatment with calcium ionophores. PMID- 4139205 TI - Surface antigens of differentiated muscle cells in monolayer demonstrated by immunofluorescence and cytotoxicity. PMID- 4139206 TI - Rosette formation by lymphoid cells of mice immunized to HSA using SRBC sensitized with an HSA--anti-SRBC conjugate. PMID- 4139207 TI - Preparation of monospecific antiserum to human LMW kininogen using immunoadsorbents. PMID- 4139208 TI - Rabbit C1q: purification, functional and structural studies. PMID- 4139209 TI - A method for estimation of the relative antigenic potencies of preparations containing common new antigens derived from a precursor protein (beta lactoglobulin). PMID- 4139210 TI - Isoelectric focusing of antibodies in polyacrylamide gels. PMID- 4139211 TI - The reaction of partial identity in quantitative immunoelectrophoretic patterns. PMID- 4139212 TI - Molecular heterogeneity effects of IgM immunoglobulins in radial immunodiffusion. PMID- 4139213 TI - Examination of FITC preparations. I. Measurements of the dye content of fluorescein isothiocyanate preparations. PMID- 4139214 TI - Characterization of FITC-labelled F(ab')2 fragments of IgG and a rapid technique for the separation of optimally labelled fragments. PMID- 4139215 TI - A method for the separate detection of two labelled antigens in lymphoid tissues, using two different radioisotopes and a double autoradiographic stripping technique. PMID- 4139216 TI - Ascaris sensitivity in the dog. I. Isolation and characterization of an antigen. PMID- 4139217 TI - Alpha-fetoprotein quantitation by radioelectrocomplexing. PMID- 4139218 TI - A fluorescent stain for viable rosette-forming cells. PMID- 4139219 TI - Combined immunofluorescent staining for the simultaneous detection of anti-DNP antibody and immunoglobulin class in the same cell. PMID- 4139220 TI - Chemotaxis of human polymorphonuclears in vitro. II. Technical study. PMID- 4139222 TI - Antigenically distinct populations of Neisseria gonorrhoeae: isolation and characterization of the responsible determinants. PMID- 4139221 TI - Glycosaminoglycans. A biochemical and clinical review. PMID- 4139223 TI - Independent synthesis of light and heavy chains: quantitation of light-chain production by mouse myeloma variants. AB - The rates of immunoglobulin synthesis have been examined in two MFC-11 cell lines which were independently adapted to tissue culture and in light-chain-producing variants derived from each of them. One cell line synthesized 2.5 pg immunoglobulin/cell/h, while the other synthesized 3.6 pg immunoglobulin/cell/h. The ratio of heavy and light chains in the two cell lines was approximately the same, and the size of the intracellular pool of immunoglobulin was proportioned to the rate of synthesis. Variants which had spontaneously lost the ability to produce heavy chains continued to synthesize light chains at approximately the same rate as their parent cell line. PMID- 4139224 TI - Serological distinction of mutants B6.CH(zl) and B6.M505 from strain C57BL-6. AB - A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2(b)). The finding suggests that the mutations occurred in the H-2K(b) gene, and together with data on MLR and CML challenges the current concept of H-2 regions' involvement in immune reactions. PMID- 4139225 TI - Binding of soluble immune complexes to human lymphoblastoid cells. I. Characterization of receptors for IgG Fc and complement and description of the binding mechanism. AB - In the present work we studied the expression of membrane-bound Ig (MBIg) as well as receptors for IgG Fc and complement on nine human lymphoblastoid cell lines. When MBIg and receptors for IgG Fc were compared, four categories of cell lines could be distinguished: (a) cell lines having both MBIg and receptors for IgG Fc, (b) cell lines having MBIg but lacking receptors for IgG Fc, (c) cell lines lacking MBIg but having receptors for IgG Fc, and (d) cell lines lacking both MBIg and receptors for IgG Fc. Two types of receptors for complement could be detected on the cell lines studied, one for C3-C3b and one for C3d. When sensitized red cells carrying C3b or C3d were used for rosette tests, three categories of cell lines could be distinguished: (a) cell lines having receptors for C3b and C3d, (b) cell lines having receptors only for C3d and (c) cell lines lacking both receptors. However, when a more sensitive immunofluorescent method was used instead of the rosette technique, it was found that cell lines unable to form rosettes with EAC1423b(hu) were able to bind soluble C3 or C3b which indicated the presence of these receptors on the cell surface. Inhibition experiments showed that receptors for C3-C3b and receptors for C3d are distinct and that receptors for C3-C3b and C3d are different from receptors for IgG Fc. A cell line (Raji) without MBIg but with receptors for IgG Fc, C3-C3b, and C3d was selected for use in studying the binding mechanism of soluble immune complexes to cell surface membrane. Aggregated human gamma globulin was used in place of immune complexes. Immune complexes containing complement bind to Raji cells only via receptors for complement, namely receptors for C3-C3b and C3d. Binding of immune complexes containing complement to cells is much greater than that of complexes without complement. Immune complexes bound to cells via receptors for complement can be partially released from the cell surface by addition of normal human serum as well as isolated human C3 or C3b. We postulate that such release is due to competition of immune complex bound C3b and free C3 or C3b for the receptors on Raji cells. PMID- 4139226 TI - Membrane immunoglobulins of B lymphocytes: inability to detect certain characteristic IgM and IgD antigens. AB - Hemagglutination and fluorescent antibody studies have provided strong evidence for the unavailability or absence of specific antigenic sites on membrane-bound IgM which are present in serum and intracellular IgM. Antisera specific for different parts of the molecule indicated that a portion but not all of the Fc was involved. Absorption experiments with normal and leukemic viable B lymphocytes failed to remove a population of Fc antibodies found in IgM-specific antisera. Similar findings were made for IgD, the other major membrane immunoglobulin of human peripheral blood B cells. Various interpretations of these observations are discussed. The most likely possibility appears that the C terminal portion of the heavy chains of the immunoglobulin molecule is buried in the membrane. PMID- 4139227 TI - Isolation of antigen-binding cells from unprimed mice: demonstration of antibody forming cell precursor activity and correlation between precursor and secreted antibody avidities. AB - Cells binding DNP groups conjugated to fluoresceinated mouse gamma globulin ((F)DNP-MGG) were isolated from spleens of unprimed mice using a fluorescence activated cell sorter (FACS). The isolated cells were specifically enriched at least 100-fold for anti-DNP precursor activity in an adoptive transfer assay as compared to unfractionated spleen. The fraction depleted of binding cells, although depleted of anti-DNP precursor activity, responded as well as unfractionated spleen when assayed for anticarrier (keyhole limpet hemocyanin [KLH]) precursor activity. High avidity binding cells were stained using low concentrations of (F)DNP-MGG. Medium and low avidity binding cells were stained using high concentrations of (F)DNP-MGG in the presence of free hapten which selectively blocked staining of the high avidity binding cells. Cells were supplemented with an excess of carrier-primed (KLH), nylon-purified splenic T cells and transferred to irradiated recipients. DNP-KLH was given at transfer and 5 days later. The anti-DNP plaque-forming cell (DNP-PFC) response and the avidities of the DNP-PFC in the irradiated recipients were measured by hapten inhibition of direct PFC plaque formation 12 days after transfer. At this time, very few indirect PFC were found. There was a positive correlation between the avidity of the DNP-binding cells and the avidity of the anti-DNP antibody secreted by their progeny. High avidity DNP-binding cells gave rise to predominantly high avidity anti-DNP-PFC. Medium and low avidity binding cells gave rise to medium and low avidity DNP-PFC. PMID- 4139228 TI - Restriction of gene expression in B lymphocytes and their progeny. III. Endogenous IgA and IgM on the membranes of different plasma cell precursors. AB - Fluorescent antibody staining with antibodies to the f and g locus allotype markers present on rabbit alpha-chains revealed that the alpha-chain is the heavy chain on the Peyer's patch lymphocytes which previously had been shown to be the precursors of IgA-producing plasma cells. In addition, lymphocytes which had been stripped of membrane Ig with pronase and then cultured overnight to allow the sole expression of endogenous membrane Ig were found to have either the micro chain or the alpha-chain on their membranes, but not both. These results suggest that most lymphocytes are restricted to the synthesis of one class of heavy chains at a time and that the commitment to synthesizing that particular heavy chain is maintained during the differentiation of lymphocytes into plasma cells. The proportion of lymphocytes with membrane alpha-chains is higher in the Peyer's patch and appendix, two gut-associated lymphoid tissues (GALT), than in other lymphoid tissues. Since the GALT are enriched sources of precursors for IgA producing plasma cells compared to nongut-associated tissues, the presence of cells bearing membrane alpha-chains correlates well with the relative abilities of these tissues to generate IgA plasma cells. PMID- 4139229 TI - Experimental studies on the bridging hypothesis of anaphylaxis: haptenic determinants required to elicit immediate-type reactions in calf skin by separate or concurrent sensitization with reagins of different specificity. AB - The present study has established, that cows suitably immunized with either DNP edestin (DNP-Ed), di-DNP-gramicidin-J [(DNP)(2)-Gram], respectively, or p azobenzenearsonate-Ed (ABA-Ed) synthesized and secreted reaginic antibodies (IgE) into colostrum. Whereas ABA-Ed failed to elicit more than a low response, there was however a persistent and increased antibody synthesis between 10 and 56 days after priming with DNP-Ed. Bivalent and multivalent DNP haptens differing in molecular size, degree of substitution, and rigidity were compared for their effectiveness in eliciting Prausnitz-Kustner (P-K) reactions in either newborn colostrum-deprived calves or in those 4 wk of age. The sensitization with reaginic anti-DNP antibody has been accomplished either by feeding colostrum of the immunized dam or by intradermal injection of reaginic serum or colostral whey. It could be demonstrated that equimolar doses of the bivalent alpha,N (epsilon,N-DNP-aminocaproyl-)-epsilon,N-DNP-L-lysine and the multivalent dinitrophenylated bovine serum albumin were equally effective in eliciting reactions in skin sites provided that a high affinity antibody was used for sensitization. By contrast, the comparatively rigid, bivalent hapten, (DNP)(2) Gram consistently failed to induce comparable reactions. Furthermore, it was clearly shown that optimal distances of determinant groups on the haptenic molecule are a prerequisite for positive P-K reactions, since alpha,epsilon,N-bis DNP-lysine failed to induce comparable reactions. Concurrent sensitization of skin sites with reaginic anti-DNP and anti-ABA antibodies provides the final proof that cross-linking of two adjacent reaginic molecules on the mast cell surface by a bivalent hapten is required for effective elicitation of immediate type reactions. This has been accomplished by utilizing the bivalent epsilon,N DNP-alpha,N-[(4-hydroxy-3-azobenzenearsonic acid)-phenacetyl]-L-lysine (DNP-ABA) carrying noncross-reactive haptenic groups, which was consistently effective in eliciting P-K reactions in doubly but never in singly sensitized skin sites. It is apparent from the results that equimolar doses of monovalent haptens could completely inhibit the response to DNP-ABA. The present studies finally establish that mast cells of newborn colostrum-deprived calves lack IgE molecules on their surface. Thus, mast cells of newborn calves may be unique, to investigate the molecular mechanisms involved in immediate-type reactions more precisely. PMID- 4139231 TI - Genetic control of cell-mediated lympholysis in mouse. AB - H-2 congenic mouse strains were tested in vitro to investigate the genetic control of cell-mediated lympholysis (CML). Combinations were selected such that differences in various segments of H-2 could be examined for their ability to stimulate production of effector cells and to serve as targets for lysis. Particular emphasis was directed towards understanding the roles of LD and SD. SD region differences are important in the sensitization of effector cells and they also function as strong targets for lysis, or as markers for the CML targets. LD differences are also important for sensitization of cytotoxic effector cells, but they serve only as very weak targets for lysis. Collaboration occurs between LD and SD in generation of CML. The nature of this interaction can be of two types: together LD and SD can produce CML which neither difference alone can stimulate; LD can enhance a CML response stimulated by SD-region differences alone. PMID- 4139230 TI - Inheritance of antibody specificity. I. Anti-(4-hydroxy-3-nitrophenyl)acetyl of the mouse primary response. AB - Our data suggest that fine specificity of antihapten antibodies is a useful Mendelian marker of variable (V) genes. We found that some mouse strains (e.g., C57/BL6) consistently produced heteroclitic anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies (relative affinity for related (4-hydroxy-5-iodo-3 nitrophenyl)acetyl and (4-hydroxy-3.5-dinitrophenyl)acetyl was always >2) while other strains (e.g., CBA) produced "conventional" anti-NP antibodies (relative affinities were consistently <1). 48 (CBA x C57BL/6)F(1) mice were studied and most of them had heteroclitic anti-NP antibodies. They were backcrossed to the recessive CBA parent, and 87 backcross animals were similarly tested. Those heterozygous for the C57BL/6 heavy (H)-chain allotype were similar to the C57BL/6 and the F(1) mice while mice homozygous for the CBA allotype were indistinguishable from the CBA. Such monogenic inheritance was observed only in the primary response. Predominance of allotype-linked genes in the control of the fine specificity characteristics was confirmed by immunizing selected homozygous mouse strains. These mice contained various mixtures of genes from C57BL, BALB/c, and other strains. Specificity of their anti-NP was exclusively determined by genes linked to the H-chain allotype, no influence could be attributed to other genes including the H-2-linked genes. PMID- 4139232 TI - Protective and cellular immune responses to idiotypic determinants on cells from a spontaneous lymphoma of NZB-NZW F1 mice. AB - A spontaneous lymphoma (141) producing monoclonal IgM is established in NZB/NZW F(1) (B/W) mice who spontaneously develop an autoimmune disease. Idiotypic determinants of 141 IgM are present on the lymphoma cell surface as shown by indirect immunofluorescence and specific cytotoxicity with rabbit anti-idiotypic antiserum. Fluorescence and cytotoxicity are inhibited by 141 IgM but not by 104E IgM, a monoclonal IgM produced by a BALB/c plasmacytoma. Immunization of B/W mice with 141 IgM before transplantation of lymphoma 141 confers protective immunity. No such protection occurs after immunization with 104E IgM or other unrelated proteins. Protected mice contain spleen cells cytotoxic for 141 lymphoma cells. This cytotoxicity is blocked by incubation of spleen cells with 141 IgM but not with 104E IgM. Moreover, splenic lymphocytes from protected mice are stimulated to synthesize DNA by 141 IgM but not by 104E IgM. These results suggest that specific cellular immune responses to idiotypic determinants may participate in the observed protection against challenge with the corresponding B-cell tumor. PMID- 4139233 TI - Antibody responses to antigenic determinants of influenza virus hemagglutinin. I. Thymus dependence of antibody formation and thymus independence of immunological memory. AB - Using immunodiffusion methods it has been shown that purified hemagglutinin (HA) extracted from two related strains of influenza A viruses (A/PR8/34 and A/FM1/47) have two distinct antigenic determinants, or groups of determinants. One determinant is cross-reactive while the other is strain-specific. Antisera raised in normal mice against HA were shown to contain two populations of antibody molecules, each directed against one of the determinants. Immunization of thymus deprived (TXBM) mice showed a strong thymus dependence of antibody formation to HA. However, the thymus dependence of antibody formation against the cross reactive determinant could be overcome by repeated inoculations of HA in TXBM mice, indicating a different handling of two portions of the same molecule by the immunological system. Strong, secondary-type responses to the strain-specific determinant were observed in primed thymus-deprived mice after reconstitution with virgin thymus cells, showing that specific immunological memory was elicited by this determinant despite the absence of detectable antibody secretion. These findings are interpreted as examples of immunological recognition and memory mediated by B lymphocytes and discussed in terms of mechanisms of T and B lymphocyte co-operation. It is suggested that the helper effect of T lymphocytes is exerted at a late stage in the differentiation of specific populations of B cells into antibody-secreting cells. PMID- 4139234 TI - Antibody responses to antigenic determinants of influenza virus hemagglutinin. II. Original antigenic sin: a bone marrow-derived lymphocyte memory phenomenon modulated by thymus-derived lymphocytes. AB - Mice immunized sequentially with two related influenza virus hemagglutinins (HA) produced a secondary antibody response with two different specificities. Some antibodies were specific for determinants common to both HA's. Paradoxically, some antibodies were directed to determinants existing only in the HA first encountered. Primed spleen cells treated with anti-theta serum and complement were transferred from animals immunized with the first HA to either normal, irradiated, or thymus-deprived recipients. These memory cells were boosted in the recipients with either the homologous or the heterologous cross-reacting HA. B memory lymphocytes were shown to be directly triggered by both HA's and to be able to secrete, independently of T lymphocytes, antibodies to both kinds of determinants. However, T cells were shown to modulate this secondary response by either enhancing or suppressing antibody secretion by B-memory cells, depending on experimental conditions. These results are discussed in terms of antigen recognition by B cells and of kinetics of development of immunological memory. PMID- 4139235 TI - Genetic control of the antibody response to poly-L(Tyr,Glu)-poly-D,L-Ala--poly-L Lys in C3H--CWB tetraparental mice. AB - In order to further delineate the mechanisms underlying genetic unresponsiveness, tetraparental mice were constructed from immune response-1A gene high responder and low responder parental genotypes, then were immunized with poly-L-(Tyr,Glu) poly-D,L-Ala--poly-L-Lys ((T,G)-A--L). An analysis of the total serum allotype mixture and of the antigen-binding capacity of the separated allotypes demonstrated that in the milieu of a tetraparental mouse, both high and low responder B cells could be stimulated equally to produce identical high titered anti-(T,G)-A--L responses. Furthermore, these studies show that effective stimulation could occur across a histocompatibility disparity. PMID- 4139237 TI - Immunochemical studies on mannans of the genera Kluyveromyces and Saccharomyces. PMID- 4139236 TI - Activation of T and B lymphocytes in vitro. III. Presence of Ia determinants on allogeneic effect factor. AB - Observations from our own laboratories, as well as those of others, have demonstrated the critical role of histocompatibility gene products in governing the cell-cell interactions concerned with development and regulation of immune responses in several species (8-12). In mice, the relevant genes concerned have been shown to be located in the K end of the H-2 complex, i.e. in the K and/or I See PDF for Structure regions (13, 14). These discoveries have placed histocompatibility gene products on a more complex level of biologic function than was heretofore generally considered (15). Thus, the hypothesis was made from these observations that genes in the H-2 complex coded for products involved in the development of effective cell-cell interactions in the immune response (8, 9, 15). The recent identification of cell surface macromolecules on lymphocytes and macrophages, that may be distinct from immune response gene products but are likewise coded for by genes in the I region, has provided a group of suitable candidate molecules for such a role (2). In our initial studies on the biological and biochemical characteristics of AEF, we were impressed by the apparent preferential activity of the highly purified AEF preparations on B lymphocytes syngeneic to the activated T-cell population from which the AEF was obtained (1). Since a prediction of the aforementioned hypothesis is, of course, that the active molecules involved in regulatory immunocompetent cell interactions are gene products of the H-2 complex, and, accordingly, should be reactive with antisera directed against components of this complex, we were prompted to perform the appropriate analyses on our preparation of AEF. The experiments presented here demonstrate that the enhancing activity of AEF obtained from T cells of the H-2(d) haplotype can be specifically removed by immunoadsorbents prepared from antisera reactive with la molecules of the H-2(d) allele. Identical results were obtained in experiments with both direct and indirect absorption procedures. The possibility that the reaction of AEF with the B10.A anti-B10 (anti-Ia.8) antiserum resulted in release of some components that were in turn toxic to the cultured cells, has been made unlikely in these studies by the use of a direct adsorption method utilizing an immunoadsorbent prepared from thoroughly washed glutaraldehyde-linked antibodies. The results obtained with the (B6A)F(1) anti B10.D2 antiserum deserve some comment. This antiserum contains antibodies directed predominantly against the H-2K region specificity, H-2.31, but may also be reactive with recently determined Ia(d) specificities (5). The capacity of this antiserum to directly absorb approximately 45% of the AEF activity at the lowest concentration of AEF employed (Fig. 1) could be interpreted to indicate the reactivity of AEF with anti-H-2K antibodies. However, the data presented here are also consistent with the interpretation that partial adsorption by the direct immunoadsorbent and lack of adsorption by the indirect method (in which only a high concentration of AEF was incubated with the alloantisera) reflect reactivity of AEF with anti-Ia(d) antibodies present in this antiserum. We conclude, therefore, that the biologically active enhancing moieties of AEF bear Ia determinants and therefore are most probably gene products of the I region of the H-2 gene complex. Recent data from other investigators have shown that an antigen specific T-cell product could be specifically adsorbed by immunoadsorbents prepared from antisera directed against the K end of H-2 (16). Since the latter antisera may contain antibodies reactive with specificities of both K and I regions, it is possible that the use of selective anti-Ia sera may yield results consistent with those presented here. Taken collectively, these observations indicate that I-region gene products may be intimately involved in the mechanism of cell-cell interactions and responsible for the regulation of immune responses. PMID- 4139238 TI - An electron-microscopic examination of certain bovine mycoplasmas stained with ruthenium red and the demonstration of a capsule on Mycoplasma dispar. PMID- 4139239 TI - Influence of stress on the amount of "Gomori-positive" granules in the outer layer of the median eminence of bilaterally adrenalectomized rats. PMID- 4139240 TI - Oncorna-viral information in human glioblastoma. PMID- 4139241 TI - Effect of actinomycin-D on labelled material in the retina and optic tectum of goldfish after intraocular injection of tritiated RNA precursors. PMID- 4139242 TI - Molecular weight estimation of mouse and guinea-pig myelin basic proteins by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate: influence of ionic strength. PMID- 4139243 TI - Isoelectric focusing of CSF proteins in neurological diseases. PMID- 4139244 TI - Changes in cathepsins B-1 and D, neutral proteinase and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities in monkey brain with experimental allergic encephalomyelitis. PMID- 4139245 TI - Acoustic nerve tumors: diagnosis, surgical management and nursing care. PMID- 4139246 TI - Presidential address: Sixth annual meeting of the American Association of Neurosurgical Nurses. PMID- 4139247 TI - What are we doing? Where are we going? PMID- 4139248 TI - Neurosurgical nursing. PMID- 4139249 TI - Comparison of uptake of 67Ga-citrate and 57Co-bleomycin in tumor using a semiconductor detector. PMID- 4139250 TI - The R.N. problem: returning to active practice. PMID- 4139251 TI - Elastic tissue in chondrosarcomas. PMID- 4139252 TI - Effects of aldosterone antagonists on organ cultures of human prostatic tissue. PMID- 4139253 TI - Differentiation of pre- and postacetabular glands of schistosome cercariae using apomorphine as a stain. PMID- 4139254 TI - Supragingival and subgingival plaque and calculus formation in humans. PMID- 4139255 TI - [Ossified lymph node metastases due to osteosarcoma. Report of two cases (author's transl)]. PMID- 4139256 TI - Macromolecular components of the luminal fluid from the bovine uterus. PMID- 4139257 TI - The effect of mestranol and lynoestrenol on ovarian histamine in the rat. PMID- 4139258 TI - Separation of human serum components capable of inducing the acrosome reaction in hamster spermatozoa. PMID- 4139259 TI - Light and electron microscope studies on lipid stained by malachite green in the male reproductive tract of the rabbit, hamster and mongoose. PMID- 4139260 TI - Cystic fibrosis: current concepts. PMID- 4139261 TI - Another human chimaera. PMID- 4139262 TI - Inherited partial duplication of chromosome No. 15. PMID- 4139263 TI - Partial trisomy 12 in a mentally retarded boy and translocation (12;21) in his mother. PMID- 4139264 TI - An unusual chromosomal segregation in a family with a translocation between chromosomes 3 and 12. PMID- 4139265 TI - 48,XXX, plus 18 double trisomy. PMID- 4139266 TI - The interpretation of freeze-etch replicas from plant cell walls. PMID- 4139267 TI - A simple method of preparing 1-2 microm sections of large tissue blocks using glycol methacrylate. PMID- 4139268 TI - Electron microscopy of the stacked disk aggregate of tobacco mosaic virus protein. II. The influence of electron irradiation of the stain distribution. PMID- 4139269 TI - Nuclear glutamate dehydrogenase: unique antigenic determinants and determinants common to the mitochondrial enzyme. PMID- 4139270 TI - Studies on the control of nucleolar number in mammalian cells: effects of thyroid hormones, sex and strain specificity in mouse hepatocytes. PMID- 4139271 TI - An ultrahistochemical study on glycogen in cow Purkinje fibres. PMID- 4139272 TI - Purkinje-myocardial conduction delay: an alternative explanation. PMID- 4139273 TI - Immunodiffusion studies of canine lymphosarcoma antigens. PMID- 4139274 TI - Macrophages in solid tumors. I. Immunologically specific effector cells. PMID- 4139275 TI - Application of an automated particle analysis system to the quantitation of virus particles. PMID- 4139276 TI - Specificity of 51Cr-release cytotoxicity of lymphocytes immune to murine sarcoma virus. PMID- 4139277 TI - HL-A expression on the G1, S, and G2 cell-cycle stages of human lymphoid cells. PMID- 4139278 TI - Histologic changes in livers of pyridoxine-deprived baboons--relation to alpha1 fetoprotein and liver cancer in Africa. PMID- 4139279 TI - Immunoelectronmicroscopic analysis of surface antigens common to Mycobacterium bovis (BCG) and tumor cells. PMID- 4139280 TI - Shared antigens between Mycobacterium bovis (BCG) and neoplastic cells. PMID- 4139281 TI - Antigenicity of murine skin tumors induced by ultraviolet light. PMID- 4139282 TI - Alterations in membrane structure and function associated with neoplastic transformation in vitro. PMID- 4139283 TI - The fine structure of Purkinje fiber glycogen. A comparative study of negatively stained and cytochemically stained particles. PMID- 4139284 TI - Membrane organization in mouse spermatozoa revealed by freeze-etching. PMID- 4139285 TI - Uncommon paracrystalline structures formed in the endoplasmic reticulum of the integumentary cells of Diplotaxis erucoides ovules. PMID- 4139286 TI - Ultrastructure of some pelecypod adductor muscles. PMID- 4139287 TI - Close-to-life preservation of Staphylococcus aureus mesosomes for transmission electron microscopy. PMID- 4139288 TI - Efferent neurites to capsular muscles in the eye of a snail, Helix aspersa. PMID- 4139289 TI - Expression of the major internal viral polypeptide in cells transformed by wild type and temperature-sensitive murine sarcoma virus. AB - Phenotypic expression of the murine intraspecies and interspecies antigenic determinants of the major type C viral structural 30,000-dalton polypeptide, p30, was measured by radioimmunoassay inhibition in cell lines from different species. Uninfected normal rat kidney (NRK) cells did not contain detectable levels of murine intraspecies and interspecies p30 antigen, whereas rat cells transformed by and producing murine sarcoma virus (MSV)-Moloney leukemia virus (M-MSV-MuLV) contained high levels of both murine intraspecies and interspecies p30 antigen. Significant amounts of murine intraspecies and interspecies p30 antigen were detected in wild-type MSV-transformed nonproducer NRK cells. The control of p30 antigen expression was examined in temperature-sensitive MSV-transformed nonproducer cells [NRK(MSV-1b)] which are cold sensitive for maintenance of the transformed phenotype. Both murine intraspecies and interspecies p30 antigens were detected in NRK(MSV-1b) cells when grown at the permissive (39 C) or nonpermissive (33 C) temperature, suggesting that p30 antigen expression is not correlated with maintenance of the transformed phenotype. The results demonstrate that previously undetectable p30 antigens are expressed in MSV-transformed nonproducer NRK cells, and suggest that the expression of p30 antigen may be a useful marker for viral gene expression in mammalian cells. PMID- 4139290 TI - Sarcoma and helper-specific RNA tumor virus subunits in transformed nonproducer mouse cells activated to produce virus by treatment with bromodeoxyuridine. AB - A tumor line (58-2T) was established from a slowly growing tumor in a BALB/c mouse inoculated with M58-2 cells. The latter clonal cell line was isolated after bromodeoxyuridine treatment as a flat variant from nonproducer BALB/3T3 cells transformed by the Kirsten sarcoma virus. The 58-2T cells produced type C virus with two discrete virus-specific RNA species. One of the species, which was probably an endogenous virus RNA subunit, had a sedimentation coefficient of 35S as the largest major subunit, and had sequences similar to Rauscher leukemia virus RNA based on nucleic acid hybridization. The other RNA species had 30S as the largest major subunit and corresponded to Kirsten sarcoma virus-specific RNA. These two RNA species formed heterogeneous, 60 to 70S, high-molecular-weight RNA in virions.DNA transcripts (58-2T DNA) from the activated virus contained base sequences complementary to Rauscher leukemia virus and Kirsten sarcoma virus. The Kirsten sarcoma virus-specific DNA sequences (58-2TS) were purified from 58-2T DNA by eliminating RLV-specific sequences. PMID- 4139291 TI - Biological expression of antigenic determinants of murine leukemia virus proteins gp69-71 and p30. AB - Antisera to purified structural proteins of Rauscher murine leukemia virus, the major envelope glycoprotein, gp69/71, and the major internal protein, p30, were studied by immunofluorescence of viable and fixed virus-infected cells and by virus neutralization. Group-specific and type-specific determinants of gp69/71 were demonstrated by immunofluorescence and virus neutralization tests, indicating that these determinants are located in the cytoplasm and probably on the cell surface as well as on virus envelope. Antisera against p30 showed anti group and anti-interspecies activities by immunofluorescence with no virus neutralizing activity. Both antigenic determinants of gp69/71 were sensitive to guanidine-hydrochloride and to a lesser degree to ether treatment, whereas the group-specific determinants of p30 were relatively stable to these treatments. PMID- 4139292 TI - Structural proteins of mammalian oncogenic RNA viruses: immunological characterization of the p15 polypeptide of Rauscher murine virus. AB - The immunological properties of the purified 15,000-dalton protein of Rauscher murine type-C virus were analyzed by radioimmunoassay. The majority of the antigenic determinants of this protein were found to be remarkably specific to Rauscher and Friend virus and to a lesser extent to Moloney virus. Determinants reactive with other murine viruses (group-specific) or type-C viruses of other species (interspecies) were also demonstrated but were minor components of the total antigenic specificities of the protein. The results provide evidence that the antigenic properties of this protein specify the Friend-Moloney-Rauscher subgroup of type-C viruses. PMID- 4139293 TI - [Pulmonary lesions associated with chemotherapy for cancer (author's transl)]. PMID- 4139294 TI - [The effect of drugs on the endocrine function tests (author's transl)]. PMID- 4139295 TI - Mapping of antibiotic resistance markers in Mycobacterium smegmatis. PMID- 4139296 TI - Development of resistance to and dependence on streptomycin in Mycoplasma pneumoniae in vitro. PMID- 4139297 TI - Electron microscopic observations of lipid antigens with special reference to the Wassermann antigen. PMID- 4139298 TI - In vitro synthesis of reovirus genomic segments. PMID- 4139299 TI - Hepatic artery ligation for metastastic leiomyosarcoma of the liver. PMID- 4139300 TI - [Sensitivities of atypical mycobacteria to various drugs. II. Sensitivities to commonly used antibiotics, some of anti-neoplastic agents, an anti-leprotic and an antifungus agent (author's transl)]. PMID- 4139301 TI - [Histopathologic study on nephrotoxocity of tuberactinomycin-N, with special reference to interrelation between nephrotoxicity and ototoxicity (author's transl)]. PMID- 4139302 TI - [Post-extrasystolic delay of atrio-ventricular conduction]. PMID- 4139303 TI - [Antithrombotic action of nicotinic acid]. PMID- 4139304 TI - [Clinical evaluation of antiarrhythmic effect of thyrocalcitonin]. PMID- 4139305 TI - [Clinical pharmacological effect of Soviet-made adrenergic beta receptor blockader Benzoral]. PMID- 4139306 TI - DNA synthesis in peripheral blood leucocytes following renal transplantation. PMID- 4139308 TI - [Methodological approaches to the study of immunoglobulin G subclasses]. PMID- 4139307 TI - Neurosecretion and sodium excretion. PMID- 4139309 TI - [Isolation of immunoglobulin G from small quantities of human serum]. PMID- 4139310 TI - [Obtaining an antiserum to human free light and heavy chain immunoglobulin G]. PMID- 4139311 TI - [Immunoglobulins in certain dermatoses]. PMID- 4139312 TI - [Obtaining immunoglobulin with antibody activity to the hepatitis-associated antigen (HAA) by means of electrodecantation]. PMID- 4139313 TI - [Identification and quantitative separation of serum proteins on polyacrylamide gel]. PMID- 4139314 TI - [Identification of urinary protein fractions (uroproteins) after disc electrophoresis on polyacrylamide gel]. PMID- 4139315 TI - [Electrophoretic analysis on polyacrylamide gel of glycosaminoglycans]. PMID- 4139316 TI - [Utilization of Lowry's method for determining the protein content in the urine of healthy children]. PMID- 4139317 TI - [Biochemical nature of the bile color reaction]. PMID- 4139318 TI - [Attempt at evaluating and controlling the accuracy of biochemical analyses]. PMID- 4139319 TI - [Cytological diagnosis of malignant neoplasms of the rectum and colon]. PMID- 4139320 TI - [Clinical laboratory evaluation of the lymphocyte stimulation test in cancer (a review of the literature)]. PMID- 4139322 TI - [Universal device for piston dose distributor]. PMID- 4139321 TI - [Detection of specific antibodies to the hemagglutinin of the epidemic parotitis virus using the erythrocyte disaggregation reaction]. PMID- 4139323 TI - [Laboratory equipment for shaking]. PMID- 4139325 TI - [Use of the "Reanal" firm's gel electrophoresis apparatus (model 69) for disc electrophoresis]. PMID- 4139324 TI - [Serial collectorless DEAE-cellulose chromatography (based on the example of isolating serum fractions containing the immunoglobulins gamma-G, gamma-A and gamma-M)]. PMID- 4139326 TI - [Use of individual ammonium 14-tungsto-4-molybdo-2-phosphate for determining protein in biological fluids]. PMID- 4139327 TI - [Change in the gastric secretory function in acetic acid poisoning]. PMID- 4139328 TI - [Detection of minimal quantatities of virus in large volumes]. PMID- 4139329 TI - [Device for the measurement of precipitates in radial immunodiffusion]. PMID- 4139330 TI - [Miniature apparatus for reverse immunoelectroosmophoresis on agar (AMVIE)]. PMID- 4139331 TI - [In memoriam N. P. Piatnitskogo]. PMID- 4139332 TI - [Desferal test as a criterion of therapeutic effectiveness of iron therapy of anemia]. PMID- 4139333 TI - [Micromethod of leukoconcentration for the diagnosis of infectious mononucleosis]. PMID- 4139334 TI - [Early diagnosis of infectious mononucleosis under polyclinical conditions]. PMID- 4139335 TI - [Method of fluorescence microscopy of cytological preparations from the nasal mucosa]. PMID- 4139336 TI - [Cytological diagnosis of dyshormonal hyperlasia and breast cancer under polyclinical conditions]. PMID- 4139337 TI - [Use of the agglomeration test in the treatment of patients with pulmonary tuberculosis in a hospital and an outpatient clinic]. PMID- 4139339 TI - [Immunological tests in myocardial infarct]. PMID- 4139338 TI - [Method of controlled conjuation of fluorescein isothiocyanate with anti influenza horse gamma globulin]. PMID- 4139340 TI - [Study of blood serum insulin with the aid of devices for radioimmunological analysis]. PMID- 4139341 TI - [Polarographic examination of bile in diseases of the liver and biliary tract]. PMID- 4139342 TI - [Method of determination of the dissociation curve of oxyhemoglobin]. PMID- 4139343 TI - [Study of kinetics of mitochondrial respiration within the range of low oxygen concentrations]. PMID- 4139344 TI - [Method of quantitative analysis of free amino acids of the blood serum]. PMID- 4139345 TI - [Effect of transport and storage on the composition of blood samples collected for analysis]. PMID- 4139346 TI - [Obtaining of erythrocytic diagnostic agent for indirect hemagglutination reaction in meningococcal infection]. PMID- 4139348 TI - [Dosage apparatus as means of minor mechanization in the practice of a laboratory department]. PMID- 4139347 TI - [Detection of dissociation of tularemia microbe cultures by the method of staining of colonies]. PMID- 4139349 TI - [Choice of a colorimeter for unified methods of laboratory studies]. PMID- 4139350 TI - [Esophageal tube and method of its use]. PMID- 4139351 TI - [Comparative characteristics of cytochemical methods of detection of intracellular hemoglobin]. PMID- 4139352 TI - [Method of determination of blood sodium and potassium by flame photometer]. PMID- 4139353 TI - [Organization of bacteriological examination for the detection of meningococcus under large-city conditions]. PMID- 4139354 TI - [Dvice for studying interrelations between the microorganisms in vitro]. PMID- 4139355 TI - [Method of preparation and use of the indicator discs with carbohydrates]. PMID- 4139356 TI - [Set of stamps for the work in a bacteriological laboratory]. PMID- 4139357 TI - [Use of a medical ultraviolet (FMU-1) photometer for determination of enzymatic activity of blood]. PMID- 4139358 TI - [Sterilization of selective glass electrodes]. PMID- 4139359 TI - [In memory of O.I. Andreeva]. PMID- 4139361 TI - [Modification of a quantitative method of fibrinogen B determination]. PMID- 4139360 TI - [Dysfibrinogemia (literature survey)]. PMID- 4139362 TI - [Correlative relationship between blood coagulation indicators of practically healthy persons]. PMID- 4139363 TI - [Determination of heparin in blood plasma]. PMID- 4139364 TI - [Changes in the blood coagulation system in patients with serum hepatitis with hemorrhagic syndrome]. PMID- 4139365 TI - [Changes of certain indicators of blood coagulation in patients with coronary arteriosclerosis and hypertensive disease]. PMID- 4139366 TI - [Possibility of diagnosis of acute thrombosis by the symptoms of hypocoagulemia. Studies in vitro]. PMID- 4139367 TI - [Simple method of determination of blood progesterone of pregnant women with the aid of competitive protein binding]. PMID- 4139368 TI - [Determination of pregnanediol in urine by the method of thin layer chromatography on silica gel]. PMID- 4139369 TI - [Quantitative determination of pregnanediol in urine by the method of gas-liquid chromatography]. PMID- 4139370 TI - [Gas-chromatographic determination of estriol and estrone in women with a normal course of pregnancy]. PMID- 4139371 TI - [Gas-chromatographic determination of pregnanediol in urine of pregnant women]. PMID- 4139372 TI - [Determination of ultraviolet ray absorbing substances in blood serum]. PMID- 4139373 TI - [Analysis of the seeding ability of pertussis microbes in examining the patients and children in contact]. PMID- 4139374 TI - [Use of serological methods for the study of the common origin of Vibrios isolated during acute gastroenteritis]. PMID- 4139375 TI - [Method of isolation and identification of halophilic Vibrios]. PMID- 4139376 TI - [Use of preservatives in detection of intestinal Protozoa]. PMID- 4139377 TI - [Use of a fluid filter for the examination of great volumes of water for cholera microbes]. PMID- 4139378 TI - [Certain data concerning the biological properties of fibrinogen B]. PMID- 4139379 TI - [Method of quantitative determination of thrombolysis]. PMID- 4139380 TI - [Fractionating analysis of cortisol and corticosterone in blood plasma by thin layer chromatography]. PMID- 4139381 TI - [Effect of blood serum dilution on the results of determination of aminotransferases by Reutman and Frenkel's method]. PMID- 4139382 TI - [Use of a quantitative method of determination of blood bilirubin in clinical practice]. PMID- 4139383 TI - [Importance of determination of specific weight of plasma for the treatment of patients with dehydration]. PMID- 4139384 TI - [Evaluation of a new test for differentiation of Pseudomonas aeruginosa from similar bacteria]. PMID- 4139385 TI - [Apparatus for electrophoresis in starch gel]. PMID- 4139386 TI - [Use of microphotometer IFO-451 for photometry of electrophoregrams in polyacrylamine gel]. PMID- 4139387 TI - [Semiautomatic attachment for Ostwald's viscosimeter]. PMID- 4139388 TI - Platelet and leukocyte aggregation associated with antigenic leukocyte histamine release. PMID- 4139389 TI - Fine structural localization of endogenous peroxidase activity in inner medullary interstitial cells of the rat kidney. PMID- 4139390 TI - Mast cells in the rat alveolar septa undergoing fibrosis after ionizing irradiation. Ultrastructural and histochemical studies. PMID- 4139392 TI - The PVC, Part II: Treatment. PMID- 4139391 TI - Carcinoma of the thyroid gland: current therapy. PMID- 4139393 TI - Cell recognition based on natural morphological nuclear markers. PMID- 4139394 TI - Possible relation of gastrin and histamine receptors in gastric hydrochloric acid secretion. PMID- 4139395 TI - [Letter: Anticoagulation control--therapeutic level]. PMID- 4139396 TI - [Attack on liver cancer--what's the value of diagnosis and treatment?]. PMID- 4139397 TI - [Simulating--an old concept with a new meaning]. PMID- 4139398 TI - Sim One: a computer-controlled patient simulator. PMID- 4139399 TI - Teaching interpersonal relations for the practice of medicine. PMID- 4139400 TI - ["If the simulator would be interesting it should be better than the real situation"]. PMID- 4139401 TI - [An audio-visual course in general pathology--a new instruction system]. PMID- 4139402 TI - [Some practical advice on instructional aids]. PMID- 4139403 TI - Intensive immunosuppression in the treatment of multiple sclerosis. PMID- 4139404 TI - Results of administering B.C.G. to patients with melanoma. PMID- 4139405 TI - Controlled clinical trial of four short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis. PMID- 4139406 TI - Inhibition of gastrin and gastric-acid secretion by growth-hormone release inhibiting hormone. PMID- 4139407 TI - Prenatal diagnosis of xeroderma pigmentosum. Report of the first successful case. PMID- 4139408 TI - Inter-laboratory variation in measurement of blood-lead levels. PMID- 4139409 TI - Renal papillae and intrarenal reflux in the pig. PMID- 4139410 TI - Plasma uptake of dopamine and 5-hydroxytryptamine and plasma-catecholamine levels in patients with Huntington's chorea. PMID- 4139411 TI - Lupus erythematosus: a disease of D.N.A. discard? PMID- 4139412 TI - Editorial: Treatment of malignant melanoma. PMID- 4139413 TI - Editorial: V.U.R. plus I.R.R. equals C.P.N.? PMID- 4139414 TI - Editorial: Private beds. PMID- 4139415 TI - Editorial: Dopamine and G.A.B.A. in Huntington's chorea. PMID- 4139416 TI - Editorial: Pathologists in training. PMID- 4139418 TI - Editorial: Costs and benefits. PMID- 4139417 TI - Editorial: Slow-K, quick quick, slow. PMID- 4139419 TI - Diseases of the lung. PMID- 4139420 TI - Measurement of pain. PMID- 4139421 TI - Effect of clothing on dispersal of Staphylococcus aureus by males and females. PMID- 4139422 TI - Clothing design for operating-room personnel. PMID- 4139423 TI - Letter: The nurses' reward. PMID- 4139424 TI - Letter: The pill off prescription? PMID- 4139425 TI - Letter: Whooping-cough vaccination. PMID- 4139426 TI - Letter: Oral contraceptives and health: thromboembolic disease. PMID- 4139427 TI - Letter: Plasma-gastrin and acid secretion in peptic ulceration. PMID- 4139428 TI - Letter: Side-effects of minocycline hydrochloride. PMID- 4139429 TI - Letter: Disinfection of respirators. PMID- 4139430 TI - Letter: Epidemiology of Crohn's disease. PMID- 4139431 TI - Letter: Penicillamine and zinc. PMID- 4139432 TI - Letter: Serum-transaminase levels and salicylates. PMID- 4139433 TI - Letter: Human placental lactogen and fetal abnormality. PMID- 4139434 TI - Letter: Influenza and ventricular septal defect. PMID- 4139435 TI - Letter: Screening for spina bifida. PMID- 4139436 TI - Letter: Predicting response of human cancer to chemotherapy. PMID- 4139437 TI - Letter: Gluten-free diet. PMID- 4139438 TI - Letter: Post-hysterectomy syndrome. PMID- 4139439 TI - Letter: Low-dose heparin. PMID- 4139440 TI - Letter: Decreased sensitivity to oral anticoagulant therapy after attacks of migraine. PMID- 4139441 TI - Letter: Malfunction of the Cardiff pump. PMID- 4139442 TI - Letter: Neonatal hyperbilirubinaemia and oxytocin. PMID- 4139443 TI - Letter: Biochemical lesion in pernicious anaemia. PMID- 4139444 TI - Letter: Mortality and anaemia in women. PMID- 4139445 TI - Letter: Polyethylene glycol forming a proteolytic band on agar-gel electrophoresis. PMID- 4139446 TI - Letter: Geriatric medicine. PMID- 4139447 TI - Letter: Comparison of T.R.H., L.H.-R.H., and placebo in depression. PMID- 4139448 TI - Letter: Cot deaths. PMID- 4139449 TI - Letter: Self-poisoning. PMID- 4139450 TI - Letter: Sodium homoeostasis in preterm infants. PMID- 4139451 TI - Letter: Food antibodies and myocardial infarction. PMID- 4139452 TI - Letter: Monoamine oxidase and migraine. PMID- 4139454 TI - Letter: Relevance of the relevant in teaching. PMID- 4139453 TI - Letter: Intestinal biopsy in lysosomal storage disease. PMID- 4139455 TI - Letter: Chronic renal failure and major surgery. PMID- 4139456 TI - Letter: Deafness and paranoia. PMID- 4139457 TI - Letter: Recovery after minor head injury. PMID- 4139458 TI - Letter: Illustrating cretinism. PMID- 4139459 TI - Letter: Multiple sclerosis: absence of fever blisters. PMID- 4139460 TI - Letter: Peak-flow meter and peak-flow gauge. PMID- 4139461 TI - Letter: Calcium balance in pregnancy. PMID- 4139462 TI - Letter: Medical computing. PMID- 4139463 TI - Letter: Inadequate mothers. PMID- 4139464 TI - Letter: HL-A antigens and diabetes mellitus. PMID- 4139465 TI - Letter: Vitamin C and schizophrenia. PMID- 4139466 TI - Letter: Prolactin and prostaglandin synthesis. PMID- 4139467 TI - Obesity, diet, and type-II hyperlipidaemia. PMID- 4139468 TI - Left-ventricular endomyocardial biopsy. PMID- 4139469 TI - Assessment of the Apgar score. PMID- 4139470 TI - Sinus histiocytosis in British and Japanese patients with breast cancer. PMID- 4139471 TI - The neuropathic urethra. PMID- 4139472 TI - B-cell neoplasia in man. PMID- 4139473 TI - Editorial: The pineal. PMID- 4139474 TI - Editorial: The consultants' contract. PMID- 4139476 TI - Editorial: Genetics of schizophrenia. PMID- 4139475 TI - Editorial: Hot spots or hot lungs? PMID- 4139478 TI - Editorial: Eking out. PMID- 4139477 TI - Editorial: Spectinomycin for gonorrhoea. PMID- 4139479 TI - Substantial or decorative? Physicians' assistants and nurse practitioners in the United States. PMID- 4139480 TI - Psychiatric disorders. PMID- 4139482 TI - Your money or your life? PMID- 4139481 TI - Nitroblue-tetrazolium tests. PMID- 4139483 TI - The consultants' contract. PMID- 4139484 TI - Letter: Research on dietary fibre. PMID- 4139485 TI - Letter: Urinary reflux and chronic pyelonephritis. PMID- 4139486 TI - Letter: Computer-assisted tomography of the brain. PMID- 4139487 TI - Letter: Minocycline: Possible vestibular side-effects. PMID- 4139488 TI - Letter: Antigenicity of monocomponent insulins. PMID- 4139489 TI - Letter: Private beds. PMID- 4139490 TI - Letter: The nurse's reward--and the doctor's. PMID- 4139491 TI - Letter: Jack becomes master? PMID- 4139492 TI - Letter: The nurse in the community. PMID- 4139493 TI - Letter: Epidemiology of Crohn's disease. PMID- 4139495 TI - Letter: Portacaval shunt in familial hypercholesterolaemia. PMID- 4139494 TI - Letter: Portacaval shunt in hyperlipidaemia. PMID- 4139496 TI - Letter: Epsilon-aminocaproic acid. PMID- 4139497 TI - Letter: Ischaemic heart-disease and diet. PMID- 4139498 TI - Letter: The vulnerable myocardium. PMID- 4139499 TI - Letter: Benign prostatic hyperplasia and cancer of the prostate. PMID- 4139500 TI - Letter: Effects of hysterectomy. PMID- 4139501 TI - Letter: Rauwolfia derivatives and breast cancer. PMID- 4139502 TI - Letter: Health services in Chile. PMID- 4139503 TI - Letter: Rapid diagnosis of arbovirus infections by counterelectrophoresis. PMID- 4139504 TI - Letter: Respiratory depression after tranquillisers. PMID- 4139505 TI - Letter: Frequency of hepatitis-B antigen or antibody in household contacts of HBAg carriers. PMID- 4139506 TI - Letter: Oestrogen synthesis by human breast carcinomas. PMID- 4139507 TI - Letter: Thallium poisoning. PMID- 4139508 TI - Letter: What is Burkitt's lymphoma? PMID- 4139510 TI - Letter: Boxers' brain damage. PMID- 4139509 TI - Letter: Cervix cancer: A clarification. PMID- 4139511 TI - Letter: Nuclear projections and chromosome abnormalities. PMID- 4139512 TI - Letter: Grey-scale ultrasonography. PMID- 4139513 TI - Letter: Respiratory-distress syndrome of the newborn, Reye's syndrome, and fatty acids. PMID- 4139514 TI - Letter: Prophylaxis for postoperative venous thrombosis. PMID- 4139515 TI - Letter: Glaucoma and HL-A antigens. PMID- 4139516 TI - Letter: Haemophilia-B carriers. PMID- 4139517 TI - Letter: Renal activity and renal filtration fraction. PMID- 4139518 TI - Letter: Drug safety and children. PMID- 4139519 TI - Letter: Liver-specific bile canalicular antibodies. PMID- 4139520 TI - Letter: Mortality and natural fluoride content of drinking-water. PMID- 4139521 TI - Letter: Mumps vaccine. PMID- 4139522 TI - Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. PMID- 4139523 TI - Clinical manifestations of halophilic non-cholera Vibrio infections. PMID- 4139524 TI - Decreased survival related to irradiation postoperatively in early operable breast cancer. PMID- 4139525 TI - Priapism during regular haemodialysis. PMID- 4139526 TI - Live vaccine used to prevent the spread of varicella in children in hospital. PMID- 4139527 TI - Site of bladder-tumour recurrence. PMID- 4139528 TI - Invertebrate model for study of macromolecular regulators of mucus secretion. PMID- 4139529 TI - Factors affecting the onset of ventricular fibrillation in hypothermia. PMID- 4139530 TI - Editorial: What becomes of the XYY male? PMID- 4139531 TI - Editorial: W.H.O. and tuberculosis. PMID- 4139532 TI - Editorial: Spinal stroke. PMID- 4139533 TI - Editorial: A chickenpox vaccine? PMID- 4139534 TI - Editorial: Management in Africa. PMID- 4139535 TI - Editorial: A virus in S.L.E.? PMID- 4139536 TI - Editorial: Coma after cardiac arrest. PMID- 4139537 TI - Cancer screening by cytology. PMID- 4139538 TI - Laboratory monitoring and screening for cancer. PMID- 4139539 TI - Breast cancer. PMID- 4139541 TI - Major disasters. PMID- 4139540 TI - Surgical self-scrutiny. PMID- 4139542 TI - Use of transport-and-culture medium combined with immunofluorescence for the diagnosis of gonorrhoea. PMID- 4139543 TI - Letter: Recovery after minor head injury. PMID- 4139544 TI - Letter: SI units. PMID- 4139545 TI - Letter: Rauwolfia derivatives and breast cancer. PMID- 4139546 TI - Letter: The pill off prescription? PMID- 4139547 TI - Letter: Premenstrual tension. PMID- 4139548 TI - Letter: Viruses in water. PMID- 4139549 TI - Letter: Assisted entry to medical schools for health workers. PMID- 4139550 TI - Letter: Epsilon-aminocaproic acid and subarachnoid haemorrhage. PMID- 4139551 TI - Letter: Low-dose heparin and stress ulceration. PMID- 4139552 TI - Letter: Beta-galactosidase deficiency in young adults. PMID- 4139553 TI - Letter: Natural history of hypertension. PMID- 4139554 TI - Letter: Doctors and social workers. PMID- 4139555 TI - Letter: Computers or nurses? PMID- 4139556 TI - Letter: Hyposplenism in ulcerative colitis. PMID- 4139557 TI - Letter: Polyethylene glycol on agar-gel electrophoresis. PMID- 4139558 TI - Letter: Heat production in brain of newborn. PMID- 4139559 TI - Letter: Inadequate mothers. PMID- 4139560 TI - Letter: N.B.T. test and endotoxaemia. PMID- 4139561 TI - Letter: Varicose veins in tropical Africa. PMID- 4139562 TI - Letter: Buronil in Huntington's chorea. PMID- 4139563 TI - Letter: Lithium in Huntington's chorea. PMID- 4139564 TI - Letter: Screening for diseases of the lung. PMID- 4139565 TI - Letter: Colonic diverticula and dietary fibre. PMID- 4139566 TI - Letter: Postoperative immunosuppression. PMID- 4139567 TI - Letter: Relapsing-fever epidemic in the Sudan and Ethiopia. PMID- 4139568 TI - Letter: Cross-reaction of human serum-proteins with HBsAg. PMID- 4139570 TI - Letter: Peak-flow meter and peak-flow gauge. PMID- 4139569 TI - Letter: Down with parameters. PMID- 4139571 TI - Letter: T-cells in chronic lymphocytic leukaemia. PMID- 4139572 TI - Letter: Unexplained tetanic spasms. PMID- 4139573 TI - Letter: Rapid recovery from neuropathy after renal transplantation. PMID- 4139574 TI - Letter: Maturation of children on anticonvulsant therapy. PMID- 4139575 TI - Letter: Specific test for multiple sclerosis. PMID- 4139576 TI - Letter: Surface characteristics of Hodgkin's lymphoma cells. PMID- 4139577 TI - Letter: Enhancement of levodopa-induced growth-hormone stimulation by practolol. PMID- 4139578 TI - Letter: Anti-inflammatory drugs and tissue copper. PMID- 4139579 TI - Letter: Cyclic A.M.P., substance P, and morphine analgesia. PMID- 4139580 TI - Letter: Viral-coded information in human rhabdomyosarcoma cells. PMID- 4139581 TI - Letter: Prolongation of skin allografts in rats by treatment with linoleic acid. PMID- 4139582 TI - Letter: Morgagni syndrome and hyperostosis frontalis interna. PMID- 4139583 TI - Letter: Defect of collagen in growth-hormone disorders? PMID- 4139584 TI - Letter: Ionising radiation and chromosomal aberrations in malnutrition. PMID- 4139585 TI - Letter: Acute arthralgia after high-dose intravenous methylprednisolone. PMID- 4139586 TI - Letter: Urinary-tract infections due to atypical Enterobacter cloacae. PMID- 4139587 TI - Reduction of sudden deaths after myocardial infarction by treatment with alprenolol. Preliminary results. PMID- 4139588 TI - Treatment of thyrotoxicosis with lithium carbonate. PMID- 4139589 TI - Monospecific antigranulocyte sera against human neutrophils, eosinophils, basophils, and myeloblasts. PMID- 4139590 TI - Combined immunosuppression and anticoagulation in rapidly progressive glomerulonephritis. PMID- 4139591 TI - Incidence of diabetes in the first 26 years of life. PMID- 4139592 TI - Vacuum blood-culture bottles inhibiting growth of Candida and fostering growth of Bacteroides. PMID- 4139593 TI - IgE and secretory otitis media. PMID- 4139594 TI - Direct evidence for involvement of erythroid cells in acute myeloblastic leukaemia. PMID- 4139595 TI - Aural temperature of the newborn infant. PMID- 4139597 TI - Editorial: A time to be born. PMID- 4139596 TI - Pathogenesis of myelopathy in cervical spondylosis. PMID- 4139598 TI - Editorial: Dangerous fever. PMID- 4139599 TI - Editorial: Serum-gentamicin. PMID- 4139600 TI - Editorial: Beyond the examining finger. PMID- 4139601 TI - Editorial: Chromosomes and computers. PMID- 4139602 TI - Editorial: Viruses in water. PMID- 4139603 TI - Editorial: Questions about blood-pressure. PMID- 4139604 TI - Cardiovascular diseases. PMID- 4139605 TI - Proposals for assisted entry to medical schools for health workers as mature students. PMID- 4139606 TI - Acute decompression sickness. PMID- 4139607 TI - Letter: Treatment of hiccup. PMID- 4139608 TI - Letter: Food and death-rates from diabetes. PMID- 4139609 TI - Letter: Prevention of some infarcts in the myocardium. PMID- 4139610 TI - Letter: Reye's syndrome. PMID- 4139611 TI - Letter: Social-work support for the Health Service. PMID- 4139612 TI - Letter: The nurse in the community. PMID- 4139613 TI - Letter: The specialty of infectious disease. PMID- 4139614 TI - Letter: Deep-vein thrombosis after hip replacement. PMID- 4139615 TI - Letter: Diet and multiple sclerosis. PMID- 4139616 TI - Letter: Inhibition of lymphocyte response to stimulants induced by unsaturated fatty acids and prostaglandins in multiple sclerosis. PMID- 4139617 TI - Letter: Computer-assisted tomography of the brain. PMID- 4139619 TI - Letter: Legal status of the unborn. PMID- 4139618 TI - Letter: Cytomegalovirus in non-B post-transfusion hepatitis. PMID- 4139621 TI - Letter: Seasonal variation of histological osteomalacia in femoral-neck fractures. PMID- 4139620 TI - Letter: Virus-like particles in hepatitis A. PMID- 4139622 TI - Letter: Double-blind trial of lithium carbonate and haloperidol in Huntington's chorea. PMID- 4139623 TI - Letter: Lithium and magnesium-dependent enzymes. PMID- 4139624 TI - Letter: Tryptophan plus a pyrrolase inhibitor for depression? PMID- 4139625 TI - Letter: Chromosome analysis of human amniotic-fluid cells. PMID- 4139626 TI - Letter: Down with parameters. PMID- 4139627 TI - Letter: Assessment of human renal transplantation. PMID- 4139628 TI - Letter: Classification of non-Hodgkin's lymphomas. PMID- 4139629 TI - Letter: Estimation of blood-carboxyhaemoglobin. PMID- 4139630 TI - Letter: Clinical trials with vitamin C. PMID- 4139631 TI - Letter: HL-A genotypes and diabetes. PMID- 4139632 TI - Letter: Vitamin-C status of institutionalised patients. PMID- 4139633 TI - Letter: HL-A 27 and rheumatoid arthritis. PMID- 4139634 TI - Letter: Traumatic encephalopathy in a young boxer. PMID- 4139635 TI - Letter: Treatment of ascites. PMID- 4139636 TI - Geoffrey Robson Webster. PMID- 4139637 TI - Ernest Muir. PMID- 4139638 TI - [4 cases of thyroid gland epithelioma stimulating hyperfixing and autonomous nodules]. PMID- 4139639 TI - [Clinical picture of chronic polyarthritis]. PMID- 4139640 TI - Editorial: Management of advanced carcinoma. PMID- 4139641 TI - [Acute undifferentiated leukemia--acute lymphocytic leukemia of adults. Differential diagnosis, prognosis, results of therapy]. PMID- 4139642 TI - The interaction of uranyl acetate with DNA. PMID- 4139643 TI - Depsipeptide modification as a method of determining the contribution of intramolecular hydrogen bonds to the conformational stability of peptides (gramicidin S). PMID- 4139644 TI - The DNA-synthesizing system of isolated mitochondria of unfertilized loach eggs and its artificial activation in vitro by the antibiotic bruneomycin. PMID- 4139645 TI - Biophysical and biochemical properties of type B oncorna viruses isolated from continuous human cell cultures. PMID- 4139646 TI - Tissue specificity and autoimmunity. PMID- 4139647 TI - Electron microscope studies of glycogen synthase. PMID- 4139648 TI - [Whipple's disease. Apropos of a case demonstrating the existence of the congenital form]. PMID- 4139649 TI - [Cytological study of nasal discharge in infants]. PMID- 4139650 TI - [Focal nodular hyperplasia of the liver]. PMID- 4139651 TI - Griseofulvin: a potential agent of chromosomal segregation in cultured cells. PMID- 4139652 TI - [On the problem of reinfection possibility of deep trichophytosis]. PMID- 4139653 TI - Induction of humoral antibody response by soluble polysaccharide of Cryptococcus neoformans. PMID- 4139654 TI - Editorial: Infectious (?) myasthenia. PMID- 4139655 TI - Prevention of chronic neonatal hepatitis B virus infection with antibody to the hepatitis B surface antigen. PMID- 4139656 TI - Thyroid storm and its management. PMID- 4139657 TI - Editorial: Type B hepatitis--good news and bad. PMID- 4139658 TI - Specificity of antigen receptors for cytochrome c in delayed hypersensitivity. PMID- 4139659 TI - RNase inhibition of reverse transcriptase activity in human milk. PMID- 4139660 TI - Dissociation of increased hexose transport from initiation of fibroblast proliferation. PMID- 4139661 TI - Preservation of antigenic properties of macromolecules over 70 Myr. PMID- 4139662 TI - C-type viruses in systemic lupus erythematosus. PMID- 4139663 TI - Antigenic specificity of retinal pigment epithelium and non-immunological involvement in retinal dystrophy. PMID- 4139664 TI - Sequence at the 3' end of globin mRNA shows homology with immunoglobulin light chain mRNA. PMID- 4139665 TI - Giemsa banding of metaphase chromosomes in triatomine bugs. PMID- 4139666 TI - Transcriptional control of alpha-foetoprotein synthesis in developing mouse liver. PMID- 4139667 TI - Intellectual functioning of children with tetralogy of Fallot: influence of open heart surgery and earlier palliative operations. PMID- 4139668 TI - Tolerance induction with bovine gamma globulin in mouse radiation chimaeras depends on macrophages. PMID- 4139669 TI - Rat liver histone modifications and their relationship to DNA-dependent RNA polymerase activities during alpha-hexachlorocyclohexane induced liver proliferation. PMID- 4139670 TI - Release of prostaglandins, a prostaglandin metabolite, slow-reacting substance and histamine from anaphylactic lungs, and its modification by catecholamines. PMID- 4139671 TI - [Chemotherapy in squamous cell carcinoma of the oral cavity]. PMID- 4139672 TI - [Administration of encephalitogenic basic protein in the diagnosis of multiple sclerosis and Guillain-Barre syndrome]. PMID- 4139674 TI - How to negotiate the ups and downs, ins and outs of body alignment. PMID- 4139673 TI - [The fine structure of central nervous tissue (author's transl)]. PMID- 4139675 TI - The dos and don'ts of traction care. PMID- 4139676 TI - DIC, disseminated intravascular coagulation. Nursing grand rounds. PMID- 4139677 TI - After anesthesia. PMID- 4139678 TI - Chest tubes: basic techniques for better care. PMID- 4139679 TI - Editorial: The rheumatic diseases: progress. PMID- 4139680 TI - [Effect of bleomycine on microvessel--microangiographical observation lung (author's transl)]. PMID- 4139681 TI - Nailing of femoral neck fractures. PMID- 4139682 TI - Immune deficiency: evaluation, diagnosis, and therapy. PMID- 4139683 TI - [Histaglobin in the prevention and treatment of recurrent obturative respiratory tract infections in children]. PMID- 4139684 TI - [Abnormal character development in children having undergone early infantile cerebral injuries]. PMID- 4139685 TI - The clinical course of lupus nephritis: relationship to the renal histologic findings. PMID- 4139686 TI - Chronic lupus erythematosus: observations on long-term survivors of "suppressive" therapy of lupus nephritis with prednisolone. PMID- 4139687 TI - Glomerulonephritis with fibrin and crescent formation. PMID- 4139688 TI - Hyalinization of the periodontal ligament incident to orthodontic tooth movement. PMID- 4139689 TI - [Vitamin D. A few new aspects]. PMID- 4139690 TI - The many meanings food has for the aged. PMID- 4139691 TI - A case study: Meckel's diverticulum. PMID- 4139692 TI - Nursing care study: corrective osteotomy of the left tibia. PMID- 4139693 TI - Symposium: care of the dying; relatives, professional care, and the dying patient. PMID- 4139694 TI - Prevention of Rh haemolytic disease. PMID- 4139695 TI - [Serum aminotransferase activity in patients treated with anticoagulants from the 4-hydroxycoumarin derivative group]. PMID- 4139696 TI - [The cofactor correlation. The metabolic block and its treatment]. PMID- 4139697 TI - [Effect of collagen on the composition of sterile exudate in Rebuck's skin window test in patients with rheumatoid arthritis]. PMID- 4139698 TI - [Urine flowmetry in patients with prostatic adenoma treated with Raveron]. PMID- 4139699 TI - Drug-induced immune hemolytic anemia. PMID- 4139700 TI - 'Prostatism'. PMID- 4139701 TI - Editorial: The Delaney "anti-cancer" Clause. The Delaney Amendment. PMID- 4139702 TI - The effects of streptomycin or dihydrostreptomycin binding to 16S RNA or to 30S ribosomal subunits. AB - Evidence is presented suggesting that streptomycin binds to 16S RNA or to 30S ribosomal subunits at the same topographical site located on the RNA chain. The equally bactericidal dihydrostreptomycin binds to the same site as streptomycin but with lower affinity. The effect of drug binding to 16S RNA (measured by reconstitution inhibition) is readily reversible, while that of drug binding to 30S subunits (measured by misreading) persists after removal of the drug. Binding of the drug is not a necessary and sufficient reason for killing. PMID- 4139703 TI - The length of the terminal repetition in adenovirus-2 DNA. AB - Adenovirus-2 DNA was end-labeled by partial digestion with Escherichia coli exonuclease III and resynthesis with the DNA polymerase from avian myeloblastosis virus and alpha-(32)P-labeled deoxyribonucleoside triphosphates. This end-labeled DNA was cleaved with several specific endonucleases and the terminal fragments were characterized by gel electrophoresis and pyrimidine tract analysis. Two endonucleases gave identical fragments from both ends, presumably from cleavage within the inverted terminal repetition, while all other endonucleases gave dissimilar fragments from the two ends. From the sizes of these fragments it is estimated that the inverted terminal repetition is between 100 and 140 nucleotide pairs long. PMID- 4139704 TI - The identity of glutathione S-transferase B with ligandin, a major binding protein of liver. AB - Evidence is presented that ligandin, an intracellular protein involved in the binding of such anions as bilirubin, indocyanine green, and penicillin, is identical to glutathione S-transferase B (EC 2.5.1.18), an enzyme catalyzing the conjugation of glutathione with such electrophiles as 1-chloro-2,4 dinitrobenzene, 1,2-dichloro-4-nitrobenzene, iodomethane, ethacrynic acid, and bromosulfophthalein. The proteins, isolated by distinct methods, have the same specificity for substrates and for ligands, react in identical fashion to antibody produced against ligandin, bear entirely similar physical characteristics and amino acid composition, and are both induced in response to phenobarbital. Indocyanine green, one of the ligands that is not effective as a substrate, was shown to competitively inhibit the conjugation reaction. It is suggested that specificity is directed toward compounds with electrophilic sites. PMID- 4139705 TI - Enzymatic synthesis of solid phase-bound DNA sequences corresponding to specific mammalian genes. AB - With oligo(dT)-cellulose as primer, RNA-dependent DNA polymerase catalyzes the synthesis of cellulose-bound DNA that is complementary to mouse globin mRNA. The resulting cellulose-bound or solid phase complementary DNA hybridizes specifically with globin mRNA and permits the recovery of intact globin mRNA. This simple technique for the synthesis of solid phase-bound complementary DNA provides an additional and convenient method for the purification of specific genetic sequences. PMID- 4139706 TI - Ferritin, a Hodgkin's disease associated antigen. AB - Antigens which exist in high frequency in tumor tissues of patients with Hodgkin's disease have been obtained in relatively concentrated form by gel chromatography procedures. Further purification and analysis of these antigens performed in the present study have demonstrated that the antigen of fast electrophoretic mobility (F-antigen) is normal tissue ferritin. The identification of F-antigen as ferritin has been made on the basis of comparative physicochemical and immunological analyses of purified F-antigen and normal ferritin. Thus, F-antigen was found to contain iron and to be similar to ferritin in molecular weight, amino-acid composition, electrophoretic mobility, isoelectric distribution, and immunological reactivity. Absorption of a monospecific heterologous anti-F antiserum with normal tissue ferritin completely removed all anti-F antibody activity. Moreover, the absorption of polyspecific heterologous antiserum to crude Hodgkin's extracts, which contains antibodies reacting with F-antigen, the slower migrating S-antigen, and a third specificity present in lysates of normal peripheral blood lymphocytes (PL-antigen), with ferritin, removed only anti-F activity, thus distinguishing the S- and PL antigens from ferritin. The existence of ferritin in high quantities in serum of Hodgkin's disease patients may provide a tool of potential diagnostic and prognostic importance in the management of this disease. PMID- 4139707 TI - Heterogeneity of HL-A antigen preparations is due to variable sialic acid content. AB - Purified, papain-solubilized preparations of HL-A antigen from cultured human lymphoblastoid cells (HL-A2 and HL-A7,12 from RPMI 4265 cells and a mixture of HL A3, W-25, HL-A12, and HL-A27 from IM-1 cells) show substantial charge heterogeneity in isoelectric focusing gels. This heterogeneity can be ascribed largely to variable numbers of sialic acid residues on each molecule. Neuraminidase (EC 3.2.1.18) treatment of the HL-A antigens as a function of time altered the band patterns in a manner demonstrating that up to three sialic acid residues are present on both first locus ("LA") and second locus ("Four") antigens. Neuraminidase treatment did not alter the specificity or specific activity of the purified antigens. PMID- 4139708 TI - Structure of antibodies with shared idiotypy: the complete sequence of the heavy chain variable regions of two immunoglobulin M anti-gamma globulins. AB - The complete amino acid sequence of the heavy chain variable regions of two different molecules of immunoglobulin M anti-gamma globulin has been determined. These proteins, from different human patients, had independently been shown to share idiotypic specificity. Only eight sequence differences were discernible for the entire length of their heavy chain variable regions. Five of the differences occurred outside hypervariable regions, while three were placeable within such regions. A comparison of these molecules of anti-gamma globulin with the seven human V(H)III variable region sequences presently available for immunoglobulins without known antibody activity showed that the great majority of sequence differences between the two idiotypically similar antibodies and these seven proteins were confined to hypervariable regions. This study illustrates in precise terms a convergence of the distinct immunological properties of idiotypy, hypervariable region structure, and combining site specificity as they relate to the variable region of the immunoglobulin molecule. To a great degree these properties now appear to be a reflection of the same structural attributes of the variable region. PMID- 4139709 TI - Material isolated from normal and variant human liver that immunologically crossreacts with alpha1-antitrypsin. AB - A material that strongly reacts with antibodies against alpha(1)-antitrypsin, but has little trypsin inhibitory capacity, has been isolated and purified to homogeneity from human liver. The molecular weight of the crossreacting material is about 18,000, which is significantly lower than that of serum alpha(1) antitrypsin. The material isolated from the liver of a homozygous variant subject (ZZ) with alpha(1)-antitrypsin deficiency is readily distinguished by electrophoresis from the material extracted from a normal (MM) subject. The tissues from a heterozygous variant subject (MZ) contain the two components. The immunologically crossreacting material is presumably synthesized by the gene that codes for alpha(1)-antitrypsin. PMID- 4139710 TI - Detection and localization of virus-specific DNA by in situ hybridization of cells during infection and rapid transformation by the murine sarcoma-leukemia virus. AB - Cytological preparations of interphase nuclei and chromosomes from mouse 3T6 cells prepared at various times after infection with the murine sarcomaleukemia virus complex were hybridized with the [(3)H]DNA product of the viral RNA directed DNA polymerase. While uninfected nuclei had an average of 4 autoradiographic grains, infected nuclei had 30 grains at 5 hr after infection and 63-65 grains at 11 and 25 hr. Virus-specific grains were localized in the chromocenters of interphase nuclei and were found also in the centromeric heterochromatin region of metaphase chromosomes. These findings provide evidence that the viral RNA-directed DNA polymerase functions to synthesize virus-specific DNA early after infection and that newly synthesized viral DNA rapidly becomes associated with or integrated into specific intranuclear sites. PMID- 4139711 TI - Surface antigens of mammalian sarcoma virus-transformed nonproducer cells. AB - In vitro, clonal BALB/3T3 mouse cells were transformed into nonproductive sarcoma cells by Kirsten murine sarcoma virus. The resulting cells are called K-BALB. Similarly, the Kirsten sarcoma virus and woolly monkey sarcoma virus transformed normal rat embryonic kidney (NRK) cells to nonproductive sarcoma cells K-NRK and W-NRK, respectively. The presence of sarcoma cell surface antigen (SCSA) on these three different cell lines has been examined by immunoelectron microscopy using the rabbit anti-K-BALB, anti-K-NRK, and anti-W-NRK sera preabsorbed with normal embryonic rat cells, NRK cells, and BALB/3T3 cells. Four different specific sarcoma cell surface antigens have been demonstrated: SCSAa, an antigen specific to the surface of W-NRK cells; SCSAb, a surface antigen common to K-NRK and W-NRK cells; SCSAc, a surface antigen common to K-BALB and W-NRK cells; and SCSAd, a surface antigen broadly reactive with the rabbit antisera to W-NRK, K-NRK, and K BALB. PMID- 4139712 TI - Variants of mouse myeloma cells that produce short immunoglobulin heavy chains. AB - After mutagenesis of cultured mouse myeloma cells with ICR 191 or Melphalan, variant clones were isolated that synthesized immunoglobulin heavy chains shorter than those produced by the parent. These variants fell into two phenotypes, based on the size, serology, and pattern of assembly of the heavy chain. Variant chains of both types no longer reacted with antisera directed either against the Fc (C terminal half of the heavy chains) or subclass-specific IgG(2b) determinants. Comparative ion exchange chromatography of tryptic-chymotryptic peptides confirmed that the variant heavy chains differed structurally from those of the parent and from each other. A conversion from one phenotype to the other has been observed. PMID- 4139713 TI - Assignment of the human gene for hexose-1-phosphate uridylyltransferase to chromosome 3. AB - Mouse-human hybrid clones were tested for the presence of human hexose-1 phosphate uridylyl-transferase (EC 2.7.7.12;UDPglucose:alpha-D-galactose-1 phosphate uridylyltransferase). Two criteria, starch gel electrophoresis and double-immunodiffusion against a human transferase-specific antibody, were used to identify human enzyme in the hybrid clones. Seventeen of 33 hybrid clones analyzed were found to contain human transferase by both criteria. Karyological analysis of the hybrid clones showed concordant segregation of human transferase with human chromosome 3. Human galactokinase was asyntenic with human transferase. We thus assign this gene to human chromosome 3. PMID- 4139714 TI - Nucleotide sequence analysis of RNA synthesized from rabbit globin complementary DNA. AB - Rabbit globin complementary DNA made with RNA-dependent DNA polymerase (reverse transcriptase) was used as template for in vitro synthesis of (32)P-labeled RNA. The sequences of the nucleotides in most of the fragments resulting from combined ribonuclease T(1) and alkaline phosphatase digestion have been determined. Several fragments were long enough to fit uniquely with the alpha or beta globin amino-acid sequences. These data demonstrate that the cDNA was copied from globin mRNA and contained no detectable contaminants. PMID- 4139716 TI - Inhibition of murine leukemia virus production in chronically infected AKR cells: a novel effect of interferon. AB - Treatment of AKR cells that had spontaneously become procedures of a murine leukemia virus with a partially purified mouse interferon (> 5 x 10(7) international mouse reference units per mg of protein) inhibited endogenous virus production. This inhibitory effect decreased over a 72-hr period in a manner similar to interferon-induced antiviral activity directed against vesicular stomatitis virus in AKR cells. Despite the inhibitory effect of interferon on infectious murine leukemia virus and viral reverse transcriptase (RNA-dependent DNA polymerase) titers in the culture fluids, intracellular levels of viral groups-specific antigens were significantly increased. These results suggest that interferon treatment in AKR cells inhibited the assembly or release of the virus. PMID- 4139715 TI - Use of the avidin-biotin complex for specific staining of biological membranes in electron microscopy. AB - To expand the electron microscopist's options in localization and visualization, a new and general staining technique has been tested. The avidin-biotin complex serves as a coupling between the electron-dense marker, ferritin, and points of interest in biological samples. When specific cellular components are tagged with biotin, those components may be visualized with ferritin-linked avidin. Because of the remarkably strong affinity of avidin and biotin (characterized by an association constant of 10(15) M(-1)), the staining is rapid and stable. The preparation of ferritin-avidin conjugate is described, and examples are presented of the application of this complex to biotin-tagged membranes. The ghosts of Acholeplasma laidlawii have been treated with biotinyl-N-hydroxysuccinimide ester to label protein amino groups. Erythrocyte membrane oligosaccharides have been oxidized by periodate or by galactose oxidase, and the resulting aldehydes labeled with biotin hydrazide. The avidin-biotin complex in electron microscopy seems especially appropriate for seqential staining procedures, as well as for visualization of reaction sites of biotin-labeled, low-molecular-weight reagents. PMID- 4139717 TI - The role of the skin in active specific immunization against leukemia in guinea pigs. AB - The L(2)C leukemia strain, which originated as spontaneous leukemia in "strain 2" guinea pigs, is transmissible by cell-graft in animals of this line; on subcutaneous inoculation it induces consistently generalized and progressive stem cell leukemia in 99% of the inoculated animals. The leukemia thus induced never regresses. However, when very small doses of leukemic cell suspensions (0.05 ml of a 10(-6) or 10(-7) dilution) were inoculated intradermally, 86 out of 180 intradermal tumors (48%) regressed spontaneously. Most of the animals that recovered from the intradermal tumors were resistant to a challenging reinoculation of leukemic cells. This resistance could be substantially increased by a second intradermal inoculation of leukemic cells. Females were more resistant than males. When 55 immunized females and 36 males received a challenging subcutaneous reinoculation (0.5 ml each) of a leukemic cell suspension of 10(-2) dilution, only two females and six males developed leukemia; the remaining 83 animals (91%) remained in good health. In a control experiment, 126 untreated "strain 2" guinea pigs were inoculated subcutaneously with the same dose, and all but one (99%) developed leukemia. The immunity thus induced could not be transferred to other animals by a serum collected from immunized guinea pigs. PMID- 4139718 TI - Cellular immunity against Rous sarcomas of chickens. Preferential reactivity against autochthonous target cells as determined by lymphocyte adherence and cytotoxicity tests in vitro. AB - Spleen cells from random-bred chickens bearing Rous sarcomas were commonly more reactive against the neoplastic target cells in autochthonous than in allogenic interactions in vitro. This difference was observed both in cytotoxic assays ((51)Cr release from labeled target cells) and in an immunoadherence test measuring attachment of (51)Cr-labeled splenocytes to Rous sarcoma cells. Specific splenocyte reactivity was not observed with normal embryonic chicken fibroblasts, 3T3 cells, or embryonic mouse C3H fibroblasts. The immunoadherence technique required only 2 hr to perform, and revealed a more consistent superiority of autochthonous recognition of Rous sarcoma cells than the cytotoxicity assay. Experiments in which both procedures were used simultaneously with identical cell populations yielded similar results, indicating that splenocyte adherence may be a precursor of and/or concomitant to target cell damage and that individual-specific tumor antigencity may play a part in cellular immunity against Rous sarcomas. PMID- 4139719 TI - Genetic control of basal serum immunoglobulin E level and its effect on specific reaginic sensitivity. AB - Studies of the distribution of total serum immunoglobulin E levels in nonallergic and allergic populations defined a cut-off point between low and high immunoglobulin E at 95 U/ml, based on Mendelian recessive inheritance of high immunoglobulin E level. Subsequent investigations of the distribution of total serum immunoglobulin E levels in 28 allergic families confirmed the recessive hypothesis. The results of quantitative skin tests in eight families, performed with between five and eight highly purified grass and ragweed pollen allergens per family, demonstrate that the immunoglobulin E-regulating gene exerts a profound effect on specific immunoglobulin E-mediated sensitivity, often masking the effect of HL-A associated immune response genes. PMID- 4139721 TI - A protein, immunologically similar to Tamm-Horsfall glycoprotein, produced by cultured baby hamster kidney cells. PMID- 4139720 TI - Analysis of the C-value paradox by molecular hybridization. AB - Poly(A)-containing RNA was isolated from ovaries of Xenopus laevis laevis and Triturus cristatus carnifex and used as a template for the synthesis of radioactive complementary DNA with RNA-dependent DNA polymerase. When annealed with an excess of homologous DNA, the complementary DNA is rendered double stranded with kinetics that suggest that the coding sequences are single-copy in both these organisms. In Triturus, these sequences are distinct from the majority of the genome, which consists of repeated sequences, and distinct from the ribosomal cistrons, which are present in proportion to the increase in C-value relative to the Xenopus genome. Moreover, the number of different poly(A) containing molecules in the ovary (sequence complexity) is the same in Xenopus and in Triturus. PMID- 4139723 TI - The intensive therapy unit and the surgical patient. PMID- 4139722 TI - Some problems in cancer management. PMID- 4139724 TI - The early detection of recurrent and metastatic oncological disease. PMID- 4139725 TI - Beating duration of cultured rat heart cells as affected by drugs and other factors. PMID- 4139726 TI - [Resection of the superficial femoral vein in the treatment of post-phlebitis syndrome. Renewal of therapeutic interest]. PMID- 4139728 TI - Border symbolism. PMID- 4139727 TI - The umbilicus as vagina substitute. A clinical note. PMID- 4139729 TI - Effects of low and high doses of L-dopa on the tetrabenazine or alpha methyltyrosine-induced suppression of behaviour in a successive discrimination task. PMID- 4139730 TI - Skid row and inner-city alcoholics. A comparison of drinking patterns and medical problems. PMID- 4139731 TI - Defects of the renal collecting systems in patients receiving anticoagulants. PMID- 4139732 TI - Tumor and skeletal imaging in bone carcinoma: an experimental demonstration. PMID- 4139733 TI - Carcinogenesis. PMID- 4139734 TI - Hidden rheumatoid factor in latex negative test sera of patients with rheumatoid arthritis. PMID- 4139735 TI - [Alpha-1-feto proteins and hepatic cirrhosis (apropos of 1 case)]. PMID- 4139736 TI - Recent progress in the studies of lead poisoning. PMID- 4139737 TI - Editorial: Effect of dicumarol on the intestinal absorption of D-mannose and D xylose. PMID- 4139738 TI - [Proteins in human bronchial washings (author's transl)]. PMID- 4139739 TI - LD50 and pathologic effects of acute and chronic administration of methamphetamine HC1 in rabbits. PMID- 4139740 TI - Computation of unbound anticoagulant values in plasma. PMID- 4139741 TI - Muscle toxicity produced by phencyclidine and restraint stress. PMID- 4139742 TI - [Comparison of haemogram and phagocytosis after intravenous application of heterologous antimacrophage or antilymphocyte sera (author's transl)]. PMID- 4139743 TI - Some aspects of histological structure of bovine extrinsic eye muscle. PMID- 4139744 TI - Comparative aspects of primate chorionic gonadotropins. PMID- 4139745 TI - Coping with the devastation of head and neck cancer. PMID- 4139746 TI - [Alpha-fetoprotein (AFP). Nature, identification and clinical value]. PMID- 4139747 TI - [Use of histomorphometric measures in normal and pathologic lumbar intervertebral disks. Preliminary study]. PMID- 4139748 TI - Effect of human anti-gamma-globulin antibodies on human lymphocytes. PMID- 4139749 TI - Studies on the induction of antibody synthesis against sulfanilic acid in rabbits. II. Effect of antibodies directed against new antigenic determinants in homologous protein. The impact on the primary immune response. PMID- 4139750 TI - Studies on the induction of antibody synthesis against sulfanilic acid in rabbits. III. Effect of antibodies directed against new antigenic determinants in homologous protein. The effect in primed or unresponsive rabbits. PMID- 4139752 TI - Differential changes in type I and type II muscle fibres in rheumatoid arthritis. A biopsy study. PMID- 4139751 TI - Oestrogenic treatment of prostatic cancer lowers the fibrinolytic activity in vein walls. PMID- 4139753 TI - Techniques for the identification of human chromosomes. PMID- 4139754 TI - Health care and education: on the threshold of space. AB - The studies described herein represent some of the most sophisticated social and technical experiments ever attempted in education and health care delivery. It is hoped that the lessons learned from them will bring us much closer to the goal of providing good quality health care and education in areas that are away from metropolitan centers. PMID- 4139755 TI - Immune and toxic mechanisms in drug-induced agranulocytosis. PMID- 4139756 TI - Are viruses concerned in the etiology of human leukemia? PMID- 4139757 TI - Immunological aspects of the etiology of human leukemia. PMID- 4139758 TI - Minimal brain dysfunction. Introduction. PMID- 4139759 TI - [Electron microscopic localization of acid mucopolysaccharide in tooth germs of rats. 1. Effect of various staining procedures (author's transl)]. PMID- 4139760 TI - [Electron microscopic localization of acid mucopolysaccharides in tooth germs of rats. II. Findings after ruthenium red staining (author's transl)]. PMID- 4139761 TI - Origins and mechanisms of specificity in clonal selection. PMID- 4139762 TI - Antigen--antibody complexes as blocking factors on the T lymphocyte surface. PMID- 4139763 TI - Rabbit allotypes--tools for the examination of gene expression in lymphoid differentiation. PMID- 4139764 TI - Serum complement related to skin lesions of systemic lupus erythematosus. PMID- 4139765 TI - Radiation therapy--What is it? PMID- 4139766 TI - Reproduction of phage conversion of the somatic antigen of Shigella flexneri on hybrids of Escherichia coli. PMID- 4139767 TI - Cytophotometric investigation of the DNA content in pigmented epithelium cells of the rat retina during postnatal ontogenesis. PMID- 4139768 TI - [Levorin tolerance in its long-term use]. PMID- 4139769 TI - Simplified oesophageal intubation for cancer palliation. PMID- 4139770 TI - [Minimal brain dysfunction in the young child]. PMID- 4139771 TI - Metabolic aspects of shock. PMID- 4139772 TI - Carcinoma of the head of the pancreas and periampullary region. PMID- 4139773 TI - An evaluation of palliative abdominoperineal resection for carcinoma of the rectum. PMID- 4139774 TI - [Biochemical indices of the blood serum in various liver diseases]. PMID- 4139775 TI - [Use of lidocaine in arrhythmias]. PMID- 4139776 TI - [Functional state of the thyroid gland in circulatory insufficiency in patients with rheumatic heart disease]. PMID- 4139777 TI - Effects of selected tissue antisera--spleen-bone marrow, brain, thyroid, pancreas, pituitary, thymus, etc.--in vivo or in vitro: a review covering 30 years researches at the University of Texas Medical Branch. PMID- 4139778 TI - [Treatment of migraine (author's transl)]. PMID- 4139780 TI - [Immunodeficiency--a cause of recurrent airway infections in adults]. PMID- 4139779 TI - A method for evaluating the effects of allograft sterilization procedures on the viability of human fibroblasts. PMID- 4139781 TI - [Treatment planning in cancer of the bladder]. PMID- 4139782 TI - Types of collagen fibres in the calcareous sponges Sycon and Leucandra. PMID- 4139783 TI - [The use of fuchsin solutions for the staining of plaques]. PMID- 4139784 TI - Association of HL-A antigens and beta 2-microglobulin: concepts and questions. PMID- 4139786 TI - The basic structure and the antigenic characteristics of HL-A antigens. PMID- 4139785 TI - The immunoglobulin-like structure of human histocompatibility antigens. PMID- 4139787 TI - Structure, evolution and significance of beta2-microglobulin. PMID- 4139788 TI - Association between the beta-2-m-HL-A molecule and membrane structures responsible for lymphocyte activation. PMID- 4139789 TI - Production of beta 2-microglobulin by normal and malignant human cell lines and peripheral lymphocytes. PMID- 4139790 TI - The subunit structure of transplantation antigens. PMID- 4139791 TI - The prolongation of renal allograft survival by an immunosuppressive peptide isolated from human plasma. PMID- 4139792 TI - [Identification of chromosomes involved in the T1-IEM translocation in mice]. PMID- 4139793 TI - [Reliability of the results of Feulgen cytophotometric determination of DNA and cell ploidy level]. PMID- 4139794 TI - The diagnostic significance of serum alpha-fetoprotein. PMID- 4139795 TI - Suprapubic prostatectomy. Modified Hryntschak technique. PMID- 4139796 TI - Role of prolactin in benign prostatic hypertrophy. PMID- 4139797 TI - Bilateral sequential germ cell tumors of testis. PMID- 4139798 TI - [Certain histochemical characteristics of the structures of the labyrinth in man]. PMID- 4139799 TI - [Visual aids in otorhinolaryngology]. PMID- 4139800 TI - Rabies-like neuronal inclusions associated with a neoplastic reticulosis in a dog. PMID- 4139801 TI - Letter: "Green gizzard" problem in broiler poultry. PMID- 4139802 TI - [The bactericidal titre, the level of properdin, gamma globulins and agglutinins in the blood of sheep infected with Salmonella abortus ovis]. PMID- 4139803 TI - Coat protein and symptom specification in tobacco rattle virus. PMID- 4139804 TI - Structural proteins of adenoviruses. X. Isolation and topography of low molecular weight antigens from the virion of adenovirus type 2. PMID- 4139805 TI - Proteolytic cleavage of the hemagglutinin polypeptide of influenza virus. Function of the uncleaved polypeptide HA. PMID- 4139806 TI - RNA-directed DNA synthesis by virions of Rous sarcoma virus: further characterization of the templates and the extent of their transcription. PMID- 4139808 TI - A study of the structure of eggplant mottled dwarf virus. PMID- 4139807 TI - The relationship of visna, maedi and RNA tumor viruses as studied by molecular hybridization. PMID- 4139809 TI - The antigenic specificity of different states of aggregation of tobacco mosaic virus protein. PMID- 4139810 TI - Properties of mouse leukemia viruses. VIII. The major viral glycoprotein of Friend leukemia virus. Seroimmunological, interfering and hemagglutinating capacities. PMID- 4139811 TI - [The mechanism of change in the bioelectric activity of the brain in tumors of the prostate gland]. PMID- 4139812 TI - [Treatment of isolated metastases from choriocarcinoma of the uterus to the lung]. PMID- 4139814 TI - [Value of immunologic indices in the diagnosis of bronchopulmonary cancers and suppurative diseases of the lungs]. PMID- 4139813 TI - [Hormonal disorders in patients with fibroadenomatosis of the breast and previous diseases of the ovaries]. PMID- 4139815 TI - [DNA quantity in the endometrial cells at different phases of the menstrual cycle in precancer and cancer]. PMID- 4139816 TI - [Whipple's disease]. PMID- 4139817 TI - [Clinico-morphologic and immunologic comparisons in immunogenic nephropathies]. PMID- 4139818 TI - [Diagnostic value of ventricular extrasystole in myocardial infarction]. PMID- 4139819 TI - [Juxtaoral organ: the importance of knowledge of this organ in oral pathology and surgery (author's transl)]. PMID- 4139820 TI - [Three years of experience in the polychemotherapy of inoperable bronchial carcinoma]. PMID- 4139821 TI - [Short report on the possibilities of an immunosuppressive treatment in pulmonary diseases]. PMID- 4139822 TI - [Arrhythmias in acute myocardial infarct]. PMID- 4139823 TI - [Therapy of arrhythmias]. PMID- 4139824 TI - [The problem of environmental pollution by lead]. PMID- 4139825 TI - [Use of indirect anticoagulants]. PMID- 4139826 TI - [Current problems of transplantation immunology]. PMID- 4139827 TI - Postnatal development of the adrenergic nerve connections and catecholamine containing cells of the rat carotid body. PMID- 4139829 TI - [Histamine liberation in man and pathogenesis of stress ulcer]. PMID- 4139830 TI - [Light-microscopy demonstration of HB-Ag in liver biopsies. Comparative studies on HB-Ag findings in the serum with results of aldehyde-thionine staining]. PMID- 4139828 TI - Tumor angiogenesis factor. Speculations on an approach to cancer chemotherapy. AB - Tumor angiogenesis factor (TAF) and its importance in determining a strategy for cancer chemotherapy are discussed. It is suggested that inhibition of RNA synthesis or increased RNA catabolism might interfere with the metabolism of solid tumor cells more so than in normal cells, and thus hinder angiogenesis and pursuant tumor growth by preventing the synthesis of the RNA component of TAF. An attempt is made to indicate potential models for anti-angiogenesis agents of this type. The drugs offered as initial prototypes for investigations along these lines are actinomycin D (which likely has antimetabolite and anti-angiogenesis activities), polyriboinosinic-polyribocytidylic acid (which likely has adjuvant and anti-angiogenesis activities) and ribonuclease (which in theory might be a purely anti-angiogenetic agent). It is noted that these models may turn out to be less than ideal as therapeutic agents due to problems of toxicity, metabolism, potency, or distribution, but nonetheless might serve to yield insights into the design of new cancer chemotherapeutic drugs. In addition, some evidence is cited suggesting that actinomycin D may be more effective against certain tumors when employed in lower, chronic dosages rather than its present use in "loading" dosages.The concept of anti-angiogenesis agents as fundamentally "tumoristatic" therapies is discussed, and the likelihood that such agents might be effectively "tumoricidal" in immunocompetent hosts is mentioned. The main promise of an anti angiogenetic strategy is efficacy against presently intractable slowly growing human cancers when used in combination with other treatment modalities. In summary, a strategy of cancer chemotherapy predicated upon interference with RNA synthesis or increase in RNA catabolism is offered as a potential mechanism for establishing anti-angiogenesis, and as a promising alternative and adjunct to present methods. PMID- 4139831 TI - [Skin changes in pheochromocytoma. Differential diagnosis of acrocyanosis and livedo racemosa]. PMID- 4139832 TI - [Pseudolymphoma syndrome (author's transl)]. PMID- 4139833 TI - [A new micro-electrophoretic proceedure for untreated liquor cerebrospinalis. Differences in the pherogram of native and concentrated proteins. Studies on the protein electrophoresis of liquor cerebrospinalis with cellulose acetate membranes, II (author's transl)]. PMID- 4139834 TI - The quantitative determination of thyroxine binding globulin by Laurell electrophoresis. PMID- 4139835 TI - Quantitation of high-molecular proteins in cerebrospinal fluid. PMID- 4139836 TI - [Automated nephelometric determination of immunoglobulin E in concentrations of micrograms per litre: the discovery of a heterologous antigen-antibody system (author's transl)]. PMID- 4139837 TI - [Electrocardiographic changes in hyperthyroidism. Studies of 542 patients]. PMID- 4139838 TI - [Study of water-soluble antigens in normal human skin]. PMID- 4139839 TI - [Influence of cytostatic drugs on antinuclear antibodies in visceral lupus erythematosus]. PMID- 4139840 TI - [The importance of the specificity of immune reactions]. PMID- 4139841 TI - [Further characterization of HeLa virus]. PMID- 4139842 TI - [Occurrence of defective lysogeny in Rhizobium lupini]. PMID- 4139843 TI - [Insensitivity of defective lysogenic Rhizobium lupini strains to homologous phage-like bacteriocins]. PMID- 4139844 TI - [Natural occurrence and clinical importance of gram-positive, non-spore-forming anaerobes]. PMID- 4139845 TI - [Effect of certain pharmacological agents on barium chloride-induced arrhythmia in rabbits]. PMID- 4139846 TI - [Effect of monomycin and paratyphoid serum on the dynamics of blood serum proteins]. PMID- 4139847 TI - [The differential diagnosis of dermatomyositis in children]. PMID- 4139849 TI - Biological properties of bone tissue conserved in plastic material and sterilized with gamma rays (clinico-experimental study). PMID- 4139848 TI - [Clinical features of microcephaly]. PMID- 4139850 TI - Revascularization of free skin graft in dependence on the recipient bed. PMID- 4139851 TI - Reaction of haemopoietic system to transplantation of homologous bone tissue. PMID- 4139852 TI - Oblique clefts of the face. PMID- 4139853 TI - Fatal thermic accidents in old people. PMID- 4139854 TI - Reconstruction of the dorsum nasi by osteperiosteal graft. PMID- 4139855 TI - Reconstruction of the abdominal wall at venter pendulus. PMID- 4139856 TI - Tendon prosthesis. PMID- 4139857 TI - The Academician Frantisek Bruian in the Balkan wars (1912--1913). PMID- 4139858 TI - In memoriam of Prof. Gustavo Sanvenero-Rosselli. PMID- 4139859 TI - Testosterone metabolism in cultured hyperplasia of the human prostate. PMID- 4139860 TI - The quest for a short-acting nondepolarizing neuromuscular blocking agent. PMID- 4139861 TI - Neuronal typology in the anuran telencephalon: a Golgi study. PMID- 4139862 TI - [Morphology of contact between mast and muscle cells in mammals]. PMID- 4139863 TI - Methods of preservation and staining of rat thymus mast cells and their interpretation. PMID- 4139864 TI - The ureterovesical junction and the musculature of the dorsal wall of the urinary bladder. PMID- 4139865 TI - Histochemical and anisotropical aspects of the rat cementum. PMID- 4139866 TI - Histochemical reactions on the localization of lipids and carbohydrates in the diencephalon and the mesencephalon of Barilius bendelisis (Ham.) and Barilius vagra (Ham.). PMID- 4139867 TI - The role of the nerve in the formation and maintenance of taste buds. PMID- 4139868 TI - Histomorphology of the male accessory reproductive organs of Suncus murinus sindensis Anderson, the common Indian shrew. PMID- 4139869 TI - Ultrastructural aspects of lipoprotein passage through oocyte envelopes and storage in ooplasm during avian vitellopoiesis. PMID- 4139870 TI - Mast cells in plaques of multiple sclerosis. PMID- 4139871 TI - The lowering effect of deep-frozen storage on the gamma-globulin concentration of the cerebrospinal fluid after encephalography. PMID- 4139873 TI - Secretory properties of chronically inflamed middle ear mucosa. PMID- 4139872 TI - Hyperacute, neutrophilic, and localized forms of experimental allergic encephalomyelitis: a review. PMID- 4139874 TI - Immunoelectrophoretic determination of serum globulins in newborn infants of diabetic mothers. PMID- 4139875 TI - Bone marrow transplantation in inbred strains of mice. I. The failure of development of normal T cell function following allogeneic transplantation. PMID- 4139876 TI - Selenium carrier proteins in mouse plasma. PMID- 4139877 TI - Red cell 2,3-diphosphoglycerate in patients with hyperthyroidism before and after treatment. PMID- 4139878 TI - Arrhythmias in the earliest phase of acute myocardial infarction. PMID- 4139879 TI - Immunopathological changes during immunosuppressive treatment of glomerulonephritis in systemic lupus erythematosus. PMID- 4139880 TI - [Monostotic cranial plasmacytoma: report of a case (author's transl)]. PMID- 4139881 TI - Heavy metals in the brain. A light microscope study of the rat with Timm's sulphide silver method. Methodological considerations and cytological and regional staining patterns. PMID- 4139882 TI - Neurohistological studies of the hypothalamo-hypophysial system of Zonotrichia leucophrys gambelii (Aves, Passeriformes). PMID- 4139883 TI - Selenium catalysis of swelling of rat liver mitochondria and reduction of cytochrome c by sulfur compounds. PMID- 4139884 TI - Childhood exposure to environmental lead. PMID- 4139886 TI - Abnormal mitral valve motion during ventricular extrasystoles: an echocardiographic study. PMID- 4139885 TI - Membrane immunoglobulins and antigen receptors on B and T lymphocytes. PMID- 4139887 TI - Idiopathic hypertrophic subaortic stenosis. Long-term surgical follow-up. PMID- 4139888 TI - Gastrointestinal protein loss in hookworm and roundworm infections. PMID- 4139889 TI - Immunologic control of soluble protein absorption from the small intestine: a gut surface phenomenon. PMID- 4139890 TI - Alpha-1-antitrypsin deficiency and pulmonary disease. PMID- 4139891 TI - A simple technic for light and electron microscopic observation of the same sections. Study of human hyperplastic lymph nodes. PMID- 4139892 TI - Letter: Screening for chronic granulomatous disease. PMID- 4139893 TI - Primary cutaneous inoculation drug-resistant tuberculosis. PMID- 4139894 TI - Possible pathogenetic role of capsular antigens in fulminant pneumococcal disease with disseminated intravascular coagulation (DIC). PMID- 4139896 TI - Glomerular deposition of tumor antigen in membranous nephropathy associated with colonic carcinoma. PMID- 4139895 TI - Remission of Cushing's disease after administration of adrenocorticotropin. PMID- 4139898 TI - Chemistry of H and E staining. PMID- 4139897 TI - The hematoxylin shortage and the availability of synthetic substitutes. PMID- 4139899 TI - Pacemaker doll. PMID- 4139900 TI - The results of split-course radiation therapy in cancer of the lung. PMID- 4139901 TI - Serum changes in rabbits experimentally infected with Trypanosoma gambiense. PMID- 4139902 TI - Intestinal trauma resulting from feeding activities of Ancylostoma caninum. PMID- 4139903 TI - Localization of the circulating antigen within the gut of Schistosoma mansoni. PMID- 4139904 TI - [Quantitative determination of different aqueous humor proteins (author's transl)]. PMID- 4139906 TI - Differences in hydration characteristics of corneas in various animal species. Histochemical study of acid mucopolysaccharides. PMID- 4139907 TI - Phenol rhizotomy in the treatment of cancer pain. PMID- 4139905 TI - [Possible significance and origin of enzymes in the vitreous body of cattle (author's transl)]. PMID- 4139908 TI - "Axoplasmic transport"--the catering and communication system within nerve cells. PMID- 4139909 TI - Effects of lidocaine and etidocaine on the axoplasmic transport of catecholamine synthesizing enzymes. PMID- 4139910 TI - Inhibition of rapid axoplasmic transport by procaine hydrochloride. PMID- 4139911 TI - Anesthetic management of the patient with hyperthyroidism. PMID- 4139912 TI - Removal of blood group determinants from bovine erythrocyte membranes. I. Action of proteolytic enzymes on ghosts. PMID- 4139914 TI - An indirect hemagglutination test for antibodies to Corynebacterium equi. PMID- 4139913 TI - Composite complement: a mixture of feline C1 and guinea pig complement as a reagent compatible with feline antibodies. PMID- 4139915 TI - Quantitative analysis of three classes of immunoglobulins in serum of newborn pigs and milk of sows. PMID- 4139916 TI - Sodium and chloride transport across the equine cecal mucosa. PMID- 4139917 TI - Sequence and rate of postmortem autolysis in guinea pig liver. PMID- 4139918 TI - The regional difference of pleural mesothelial cells in rabbits. PMID- 4139919 TI - The solitary pulmonary nodule--1974. PMID- 4139920 TI - The switch from fetal to adult hemoglobin in humans: evidence suggesting a role for gamma-beta gene linkage. PMID- 4139921 TI - Use of globin cDNA as a hybridization probe for globin mRNA. PMID- 4139922 TI - Morphological and submicroscopic comparison of sickle erythrocytes of humans and deer. PMID- 4139923 TI - Embryonic and fetal hemoglobin in animals. PMID- 4139924 TI - The K+-stimulated ATPase system of microsomal membranes from gastric oxyntic cells. PMID- 4139925 TI - Hyaline bodies of the optic papilla and bilateral acute vascular occlusions. PMID- 4139926 TI - Autonomic drugs in ophthalmology: Some problems and promises. Section IV: Sympatholytic and sympathetic blocking agents--alpha adrenergic antagonists and beta adrenergic antagonists. PMID- 4139927 TI - Palliative treatment of oesophageal cancer. PMID- 4139928 TI - C bands in human metaphase chromosomes treated by barium hydroxide. PMID- 4139929 TI - Structural variation in chromosome No 9. PMID- 4139930 TI - [Serological, immunological and immunochemical research on the presence of a specific antigenic-protein in cancer-urine (author's transl)]. PMID- 4139931 TI - Fetuin as a trypsin inhibitor. PMID- 4139933 TI - [Feto-specific alpha-1 serum protein. Significance of its finding in the blood and personal experiences]. PMID- 4139932 TI - Some ultrastructural observations on keratohyalin granules of guinea pig epidermis. PMID- 4139934 TI - The staining of free-living amoebae by indirect immunofluorescence. PMID- 4139935 TI - Ventricular irritability associated with the use of naloxone hydrochloride. Two case reports and laboratory assessment of the effect of the drug on cardiac excitability. PMID- 4139936 TI - Fenestrated endothelium of the liver sinusoids of the guinea pig as revealed by scanning electron microscopy. PMID- 4139937 TI - Action of some antibiotics on the electrical activity of intestinal smooth muscle of rat. PMID- 4139938 TI - A solicitation for referral of your patients. PMID- 4139939 TI - [Clinical aspects of the evidence dental plaques in the deciduous teeth, with erithrocin 1 percent (author's transl)]. PMID- 4139940 TI - A steroid-sensitive solitary intracranial plasmacytoma. PMID- 4139941 TI - Disorders of the corneal epithelium. A clinicopathologic study of dot, geographic, and fingerprint patterns. PMID- 4139942 TI - Preparation of undecalcified temporal bone sections. PMID- 4139943 TI - [Demonstration of fine structure of the guinea pig organ of Corti after electron microscopic silver staining (author's transl)]. PMID- 4139944 TI - Anatomical projection of the cochlea to the cochlear nuclei of the guinea pig. PMID- 4139945 TI - The chemical composition of wool. XII Further studies on cortical cells and macrofibrils. PMID- 4139946 TI - Characterization of the organophosphorus-resistant Mt Alford, Gracemere and Silkwood strains of the cattle tick, Boophilus microplus. PMID- 4139948 TI - Cerebral dysfunctions--clarification, delineation, classification. PMID- 4139947 TI - Activity of fosfomycin against Pasteurella. PMID- 4139950 TI - Nursing management of transurethral resection of the prostate. PMID- 4139949 TI - Contingent reinforcement of lowered blood-alcohol levels in an outpatient chronic alcoholic. PMID- 4139951 TI - Immunological unresponsiveness in mice. I. Immunological unresponsivenss induced in embryonic mice by maternofetal transfer of human gamma-globulin. PMID- 4139952 TI - Isotope assay of histamine release. PMID- 4139953 TI - Localization of the XG allotypic determinants, in which carbohydrate structures take part, to the separable parts of the rabbit IgG molecule. PMID- 4139954 TI - Effect of storage on microsomal mixed function oxidase activity in mouse liver. PMID- 4139955 TI - Standardized excision of small areas of rat and mouse brain with topographical control. PMID- 4139956 TI - Subcellular distribution of K-strophanthoside (3H) in isolated guinea-pig hearts. PMID- 4139957 TI - A computer assisted instructional course in diagnosis and treatment of the rheumatic diseases. PMID- 4139958 TI - The articular cartilage in familial chondrocalcinosis. Light and electron microscopic study. PMID- 4139959 TI - [Rat blood values depending on age and sex. 3. Total protein and protein fractions]. PMID- 4139960 TI - [Investigation of the local antihistamine effect of dermatological preparations]. PMID- 4139961 TI - Immunoelectrophoretic changes in Lyell syndrome. PMID- 4139962 TI - Coronary lipohyalinosis. Dietary induction in guinea pigs. PMID- 4139963 TI - Focal differences in lipid metabolism of the young pig aorta. Part 2. Synthesis from (2-14c)ethanolamine and (1,2-14C)choline. PMID- 4139964 TI - Black grain mycetoma. A study of the chemistry, formation and significance of the tissue grain in Madurella mycetomi infection. PMID- 4139965 TI - Elution of antibodies from the lymphocyte membrane in certain dermatoses. Preliminary communication. PMID- 4139967 TI - Chlamydial infection of conjunctival tissues in culture. PMID- 4139968 TI - Megakaryocyte polyploidization in acute leukaemia and preleukaemia. PMID- 4139966 TI - Identification of muscle fibre types in the experimentally denervated tibialis anterior muscle of the rabbit. PMID- 4139969 TI - Jejunal absorption rates of glucose, glycine and glycylglycine in Zambian African adults with malnutrition. PMID- 4139970 TI - The cation-binding properties of gramicidin. PMID- 4139971 TI - The conformation of gramicidin A. PMID- 4139972 TI - The aggregation of gramicidin A in solution. PMID- 4139973 TI - A 13C nuclear magnetic resonance study of gramicidin A in monomer and dimer forms. PMID- 4139974 TI - High-anti conformation in o-azanucleosides. The crystal and molecular structure of 6-azacytidine. PMID- 4139975 TI - An unbiased method for estimating binding parameters in a non-cooperative binding process. PMID- 4139976 TI - Studies on fetuin from foetal bovine serum. The composition and amino acid sequences of glycopeptides from fetuin. PMID- 4139977 TI - Asymmetric membranes resulting from the fusion of two black lipid bilayers. PMID- 4139978 TI - Isolation of nuclei and characterization of nuclear DNA of Acanthamoeba castellanii. PMID- 4139979 TI - In vitro effects of silicotungstate on some RNA viruses. PMID- 4139980 TI - The Epstein-Barr virus (EBV) in human pathology. Results of a serological investigation of a hospital population. PMID- 4139981 TI - Antibodies to Epstein-Barr virus (EBV) antigens in sera of American Burkitt lymphoma patients. PMID- 4139982 TI - The equivalence of fluctuation analysis and chemical relaxation measurements: a kinetic study of ion pore formation in thin lipid membranes. PMID- 4139983 TI - The ordered structure of the encephalitogenic protein from normal human myelin. PMID- 4139984 TI - The collection and analysis of volatile hydrocarbon air pollutants using a timed elution chromatographic technique linked to a computer controlled mass spectrometer. PMID- 4139985 TI - Treatment of acid phosphatase deficiency disorders. PMID- 4139986 TI - [Preparation of preparations for the differential staining of chromosomes]. PMID- 4139987 TI - Chlorinated hydrocarbon insecticide residues in adipose, liver, and brain samples from Iowa mink. PMID- 4139988 TI - Hexachlorobenzene (HCB) residues in fish. PMID- 4139989 TI - Effects of DDT on bobwhite quail (Colinus virginianus) adrenal gland. PMID- 4139990 TI - Short-term effects of organophosphate pesticides on cholinesterases of estuarine fishes and pink shrimp. PMID- 4139991 TI - Residual organochlorine pesticides in the fat of mutton birds of New Zealand. PMID- 4139992 TI - The susceptibility to selected insecticides and acetylcholinesterase activity in a laboratory colony of midge larvae, Chironomus tentans (diptera: chironomidae). PMID- 4139993 TI - Lead concentrations in native trout. PMID- 4139994 TI - The pigeon, a sensor of lead pollution. PMID- 4139995 TI - Intestinal absorption of hexachlorobenzene and hexachlorocyclohex and isomers in rats. PMID- 4139996 TI - Simultaneous clean up of fish fat containing low levels of residues and separation of PCB from chlorinated pesticides by thin-layer chromatography. PMID- 4139997 TI - Pesticide residues in the top soil of five West Alabama counties. PMID- 4139998 TI - Storage of organochlorine insecticides in adipose tissue of Ugandans. PMID- 4139999 TI - The content of polychlorinated hydrocarbons in Arctic mammals. PMID- 4140000 TI - Effect of dihydroergotamine on partial functions of the kidneys and water and salt metabolism in dogs with experimental hypertension. PMID- 4140001 TI - Microfluorimetric study of thermal denaturation of the nuclear DNP-complex of lymphocytes stained with acridine orange. PMID- 4140002 TI - Analysis of changes in the nuclear chromatin of peripheral blood lymphocytes in Down's syndrome. PMID- 4140004 TI - Technical difficulties in determining the origin of hair and sebaceous glands found in regenerating skin. PMID- 4140003 TI - Detection of the mucopolysaccharide component of the supraplasmalemmal covering of cells lining the alveoli of the rat lung. PMID- 4140005 TI - Double-blind cross-over trial comparing intranasal beclomethasone dipropionate and placebo in perennial rhinitis. AB - Twenty-five patients with perennial rhinitis completed a double-blind cross-over trial of intranasal beclomethasone dipropionate 200 mug daily and placebo. Of these patients 19 preferred the active drug and two preferred placebo. There were significant reductions in symptom scores for nasal obstruction and rhinorrhoea and in the use of decongestant nasal drops when using the active drug. No changes in morning plasma cortisol levels occurred during the three-week treatment period. PMID- 4140006 TI - Investigations into the role of pharmacologically active amines in anaphylaxis in calves. PMID- 4140008 TI - The axonal transport of slowly migrating (3H)leucine labelled proteins and the regeneration rate in regenerating hypoglossal and vagus nerves of the rabbit. PMID- 4140007 TI - An automated system for counting silver grains in autoradiographs. PMID- 4140009 TI - Magnesium or calcium activated ATPase in mammalian nerve. PMID- 4140010 TI - Analysis of acetylcholinesterase synthesis and transport in the rat hippocampus: recovery of acetylcholinesterase activity in the septum and hippocampus after administration of diisopropylfluorophosphate. PMID- 4140011 TI - Suppression of the in vitro and in vivo cytotoxic effects of guanethidine in sympathetic neurons by nerve growth factor. PMID- 4140012 TI - Characteristics of the retrograde axonal transport system for nerve growth factor in the sympathetic nervous system. PMID- 4140013 TI - Striate cortex projections to the lateral geniculate and other thalamic nuclei: a study using degeneration and autoradiographic tracing methods in the marmoset Callithrix. PMID- 4140014 TI - Germination studies on pure yeast ascospores. PMID- 4140016 TI - The anatomical substratum of pain evidence derived from morphometric studies on peripheral nerve. PMID- 4140015 TI - Scanning and transmission electron microscopy of the ependymal lining of the third ventricle. PMID- 4140017 TI - Biology of the human malignant lymphomas. I. Establishment in continuous cell culture and heterotransplantation of diffuse histiocytic lymphomas. PMID- 4140018 TI - Effects of bleomycin on cells in culture: a quantitative cytochemical study. PMID- 4140019 TI - The documentation of human breast cancer in tissue culture. PMID- 4140020 TI - Total knee arthroplasty. PMID- 4140021 TI - [Immunodiagnosis of tumors today]. PMID- 4140022 TI - Structural basis of atrial and ventricular conduction. PMID- 4140023 TI - Re-entry--an important mechanism of cardiac arrhythmias. PMID- 4140024 TI - Wenckebach type I and type II atrioventricular block (revisited). PMID- 4140025 TI - Pre-excitation syndrome. PMID- 4140026 TI - Exercise-induced arrhythmias--recognition, classification, and clinical significance. PMID- 4140027 TI - Contribution of atrial pacing to understanding of the genesis of arrhythmias. PMID- 4140028 TI - Prognostic significance of ventricular premature beats. PMID- 4140029 TI - The P wave: correlation of surface and intra-atrial electrograms. PMID- 4140030 TI - Refractoriness of cardiac tissue. PMID- 4140031 TI - [Clinico-therapeutic considerations on a case of hypopotassemia with numerous subentrant episodes of ventricular fibrillation]. PMID- 4140032 TI - [Radioimmunologic methods in clinical practice (author's transl)]. PMID- 4140033 TI - Distribution of large ventral horn cells in the lumbar cord of the rat. PMID- 4140034 TI - Identification of neurophysin producing cells. I. The origin of the neurophysin like substance-containing nerve fibres of the external region of the median eminence of the rat. PMID- 4140035 TI - On catecholamine-containing cells in the rat interatrial septum. Enzymatic histochemical and elctron microscopical study. PMID- 4140036 TI - Sensory structure of the tentacles of the slub, Arion alter (Pulmonata, Mollusca). 1. Ultrastructure of the distal epithelium, receptor cells and tentacular ganglion. PMID- 4140037 TI - Sensory structure of the tentacles of the slug, Arion ater (Pulmonata, Mollusca). 2. Ultrastructure of the free nerve endings in the distal epithelium. PMID- 4140038 TI - Ultrastructure of pigment cells in wild type and color mutants of the Mexican axolotl. PMID- 4140039 TI - An ultrastructural study of the subcommissural organ cells of the African clawed toad, Xenopus laevis. PMID- 4140040 TI - The diversity of the messenger RNA population in growing Friend cells. PMID- 4140041 TI - Evaluation of ligation of a branch of the portal vein for unresectable hepatic tumor. PMID- 4140042 TI - [Cyto-immunological study of variations of prolactin cells and of gonadotropic cells during the annual sexual cycle in adenohypophysis of male fox]. PMID- 4140043 TI - The RN as a neurosurgical assistant. A new concept in total patient care. PMID- 4140044 TI - In vitro autoradiographic studies of DNA synthesis in human testis with spermatogenic arrest. PMID- 4140045 TI - Editorial: Trauma, splenectomy and the risk of infection. PMID- 4140046 TI - [Cardio-auditory syndromes of genetic origin]. PMID- 4140047 TI - The temperature dependence of the response to valinomycin and gramicidin by isolated liver mitochondria from warm- and cold-blooded animals. PMID- 4140048 TI - The generation of antibody diversity: its dependence on antigenic stimulation. PMID- 4140049 TI - Radioelectrocomplexing: a general radioimmunoassay procedure for the detection of primary binding of antigen by antibody. PMID- 4140050 TI - Immunogenicity in vitro: structural correlation. PMID- 4140051 TI - Static dynamic imaging of the brain. PMID- 4140052 TI - Expression of histocompatibility antigens during the growth cycle of cultured lymphoid cells. PMID- 4140053 TI - Homogeneous antibodies: induction and value as probe for the antibody problem. PMID- 4140054 TI - [Use of electrocoagulation in the palliative treatment of cancer of the rectum]. PMID- 4140055 TI - Trypsin G- and C-banding for interchange analysis and sex identification in the chicken. PMID- 4140056 TI - Nuclear DNA content of the emu. PMID- 4140057 TI - Early complications following operations for cancer of the rectum and anus. PMID- 4140058 TI - [Erythrocytes as depot and transport system for insulin]. PMID- 4140059 TI - [Provocation of extrasystoles and paroxysmal tachycardia in horses with heart valve diseases following exertion]. PMID- 4140060 TI - Recurrent seizures induced by potassium in the penicillin treated hippocampus. PMID- 4140061 TI - Oxidative metabolism during recurrent seizures in the penicillin treated hippocampus. PMID- 4140062 TI - Masseteric and digastric reflex activity during conditioned sensorimotor rhythm. PMID- 4140063 TI - The maturation and interrelationship of EEF patterns and auditory evoked response in premature infants. PMID- 4140064 TI - Schizophrenia and EEG spectral analysis. PMID- 4140065 TI - Huntington's chorea: an electroencephalographic and psychometric study. PMID- 4140066 TI - Clinical electromyographic studies of diseases of the motor unit. PMID- 4140067 TI - Focal seizures induced by movement without sensory feedback mechanisms. PMID- 4140068 TI - Transient global amnesia with a previously unreported EEG abnormality. PMID- 4140069 TI - Differential brainstem pathways for the conduction of auditory frequency following responses. PMID- 4140070 TI - [Sleep stages in "encephale isole" preparations: I. Triggering of ponto-geniculo occipital spikes and slow-wave sleep. The role of the nuclei of the raphe]. PMID- 4140071 TI - [Sleep stages of the "encephale isole" preparation: II. Paradoxical stages. Their triggering by afferent baroceptive stimulation]. PMID- 4140072 TI - Activity of muscle spindles during muscle twitch and clonus in normal and spastic human subjects. PMID- 4140073 TI - Slow potentials of the brain related to speech processing in normal speakers and stutterers. PMID- 4140074 TI - [Influence of blood pressure variations on the level of polarization of afferent endings in the cuneate nucleus. Role of the area postrema]. PMID- 4140075 TI - [Bulbar inhibition of electrodermal activity in the cat]. PMID- 4140076 TI - Spike-and-wave afterdischarges in cortical somatosensory neurons of cat. PMID- 4140077 TI - Remote monitoring of muscle length and EMG in unrestrained cats. PMID- 4140078 TI - A new technique for functional visual deprivation. PMID- 4140079 TI - A universal bird head-holder for stereotaxic surgery. PMID- 4140080 TI - Overlapping advance control systems for microelectrode positioning. PMID- 4140081 TI - Sources of electrocochleographic responses as studied in patients with brain damage. PMID- 4140082 TI - The importance of methodology in drug studies using EEG. PMID- 4140083 TI - Purification and properties of Avian growth hormones. PMID- 4140084 TI - Alpha-fetoprotein in primary liver cancer and other diseases. PMID- 4140085 TI - Evidence of similar behaviour of zinc in intestinal crypts and pancreatic islets. PMID- 4140087 TI - [Morphokinetic effect of gestagens on the swine's testis]. PMID- 4140086 TI - The influence of estrogenic and-or progestogenic treatment on some parameters of lipid metabolism (a controlled clinical study). PMID- 4140088 TI - [Further data on the effect of the synthetic thyrotropin releasing factor on the synthesis and degradation of the thyroid hormones in the rat]. PMID- 4140090 TI - Immunologic properties of Aalpha chain of human fibrinogen. PMID- 4140089 TI - Affinity labeling and topology of the antibody combining site. PMID- 4140091 TI - Human leukemic cells: RNA-directed DNA polymerase. PMID- 4140092 TI - On the use of affinity chromatography in demonstrating the transfer of thioester bound D-phenylalanine from the light enzyme of gramicidin S synthetase to an acceptor site for this amino acid on the heavy enzyme. PMID- 4140093 TI - Viability of tumor cells in mechanically and enzymatically prepared tissue suspensions. PMID- 4140094 TI - Pituitary prolactin levels in canine mammary cancer. PMID- 4140095 TI - [Use of radio-immunologic technics in the study of the antigenicity of morphine]. PMID- 4140096 TI - [Modality and mechanism of the toxic action of organochlorine insecticides. I. Comparative study of the acute toxic effects on the hamster and the rat]. PMID- 4140097 TI - The morphological characterization of isolated nuclei in comparison to in situ nuclei from mouse cortex. PMID- 4140098 TI - Axonal regeneration and functional plasticity in the central nervous system. PMID- 4140099 TI - [Light microscopic localization of rabies virus antigen by means of peroxidase labeled immunoglobulin (On the usefulness of immunoenzyme technique)]. PMID- 4140100 TI - Interaction of lindane and diazinon on the skin of rats. PMID- 4140101 TI - The inhibitory effect of toluidine blue and methylene blue on rat mast cell damage by promethazine, chlorpromethazine and chlorpromazine. Its reversal by glucose. PMID- 4140102 TI - The location of soluble antigen in the spleen of Xenopus laevis. PMID- 4140103 TI - Lanthanum staining of the intermediate region of the cell wall in Escherichia coli. PMID- 4140104 TI - Electrostatic field induced changes in mouse serum proteins. PMID- 4140105 TI - Inability of specific antibodies to discriminate between frog and tadpole haemoglogins in mixture. PMID- 4140106 TI - Some immunochemical studies on leukocyte antigens in acute leukemia. PMID- 4140107 TI - Studies on phytohemagglutinins XXI. The covalent oligomers of lysozyme-First case of semisynthetic hemagglutinins. PMID- 4140108 TI - An ammoniacal-silver stain technique specific for satellite III DNA regions on human chromosomes. PMID- 4140109 TI - Transformation of nucleoli in vesicular gland cells of mice. PMID- 4140110 TI - Correlation between cellular manifestations of allograft response and graft rejection times. PMID- 4140111 TI - Haemagglutination and cytotoxic studies of H-2 IV. Evidence that there are 3-like antigenic sites determined by both the K and the D crossover regions. PMID- 4140112 TI - Susceptibility of different avian cells to transfection with DNA isolated from virogenic mammalian Rous sarcoma cells. PMID- 4140113 TI - Effect of host splenectomy on the course of non-H-2 allograft response in mice. PMID- 4140114 TI - Correlative histochemical and ultrastructural studies on fetal and early postnatal guinea pig ovaries, with special reference to the development of interstitial cell system. PMID- 4140115 TI - [Premature regression of the corpus luteum in cows following an injection of progestagen during early dioestrus (author's transl)]. PMID- 4140116 TI - [Histological and histochemical studies on the epithelium of the epididymis of adult boars (author's transl)]. PMID- 4140117 TI - Acid mucopolysaccharide metabolism, the cell surface, and primary mesenchyme cell activity in the sea urchin embryo. PMID- 4140118 TI - Experimental analysis of the migration and differentiation of neuroblasts of the autonomic nervous system and of neurectodermal mesenchymal derivatives, using a biological cell marking technique. PMID- 4140119 TI - Muscle and cartilage differentiation in small and large explants from the chick embryo limb bud. PMID- 4140120 TI - Cytodifferentiation of the acinar cells of the rat submandibular gland. PMID- 4140121 TI - The inheritance of cell differentiation during limb regeneration in the axolotl. PMID- 4140122 TI - A barrier to diffusion in pseudoplasmodia of Dictyostelium discoideum. PMID- 4140123 TI - Free amino acids in normal and tumorous tissues of human kidney, bladder, and prostate. PMID- 4140124 TI - [Malignant rectal and anal tumors]. PMID- 4140125 TI - [Computation of the carbon monoxide concentration in the air over highways and neighboring residential developments]. PMID- 4140126 TI - [Study and evaluation of the genetic danger from chemical substances]. PMID- 4140127 TI - [Allergenic properties of furan compounds]. PMID- 4140128 TI - [Acute occupational lindane poisoning]. PMID- 4140129 TI - [Determination of alpha-1 fetoprotein contents in amniotic fluid collected during the 1st trimester of normal pregnancy and in fetal death]. PMID- 4140130 TI - [Protracted pleurisy as an early manifestation of lupus erythematosus]. PMID- 4140131 TI - [Adenoma of the prostate and the hematological patient]. PMID- 4140132 TI - Vegetative nuclear structures and their mode of division in Cyathus species. PMID- 4140134 TI - [Skeletal scans in Sudeck's bone dystrophy (author's transl)]. PMID- 4140133 TI - Distribution of nuclei in macroconidia of dermatophytes. PMID- 4140135 TI - [Therapy of bronchial asthma using gamma glubulin. Results of treatment using standardized and blood-group differentiated gamma globulin]. PMID- 4140136 TI - [Thin-layer chromatographic identification of the phenylthiohydantoins of amino acids (author's transl)]. PMID- 4140137 TI - Isolation and molecular properties of formamidase from rat liver cytoplasm. PMID- 4140138 TI - Electron microscopic study of pyruvate dehydrogenase complex from Saccharomyces carlsbergensis. PMID- 4140139 TI - [Differentiation of proteolytic enzymes in purulent mucous secretions by selective inhibition, combined with electrophoresis-a contribution to negative enzymatic staining (author's transl)]. PMID- 4140140 TI - Deficiency of lactosyl sulfatide sulfatase in metachromatic leucodystrophy (sulfatidosis). PMID- 4140141 TI - Epithelial basement membrane of bovine renal tubuli. Isolation and chemical characterization. PMID- 4140142 TI - Hospitals offer employees health programs. PMID- 4140143 TI - A t(21q21q) ring chromosome. PMID- 4140144 TI - Cytophilic antibodies in mice contact-sensitized with oxazolone. Immunochemical characterization and preferential binding to a trypsin-sensitive macrophage receptor. PMID- 4140145 TI - Cytophilic activity of IgG2 from sera of guinea-pigs immunized with bovine gamma globulin. PMID- 4140146 TI - Interaction of anti-thymocyte serum with haematopoietic stem cells. II. Stimulation of colony formation in vitro. PMID- 4140147 TI - Further evidence for the role of macrophages in the initiation of lymphocyte trapping. PMID- 4140148 TI - Mechanism of follicular antigen trapping. Evidence for a two cell mechanism using double isotope autoradiography. PMID- 4140149 TI - Further studies on the prevention of tolerance induction by poly A:U. PMID- 4140150 TI - The production of precipitating antiglobulin reagents specific for the subclasses of human IgG. PMID- 4140151 TI - Sheep antibodies to soluble rat collagen. Isolation of cross-linked peptides by affinity chromatography. PMID- 4140153 TI - Cells involved in the in vitro stimulation by DNP-carrier complexes of in vivo primed mouse spleen cells. PMID- 4140152 TI - In vitro stimulation of spleen cells of the mouse by DNP--carrier complexes. PMID- 4140154 TI - Stimulation of lymphocyte transformation by autologous serum fractions from patients with rheumatoid arthritis. PMID- 4140155 TI - Common antibody-induced redistribution on thymocytes of strain-, species- and non species-specific antigenic determinants shared by brain and thymocytes of mice. PMID- 4140156 TI - Haemagglutination inhibition assay of the common determinants and subspecificities of Australia antigen. PMID- 4140157 TI - Cytochemical studies on the staining of DNA-aldehyde with basic dyes. PMID- 4140158 TI - Thiacetazone concentration in blood related to grouping of tubercular patients, its treatment, results, and toxicity. PMID- 4140159 TI - Alpha-fetoprotein in Indian childhood cirrhosis. PMID- 4140160 TI - Role of macrophages in resistance to murine cytomegalovirus. AB - The role of macrophages in protecting mice from murine cytomegalovirus (MCMV) was studied in Swiss, CBA/J, and C57BL/6J mice. CBA/J mice were more resistant to virus than were C57BL/6J mice at all ages tested. Prior treatment of adult Swiss mice with 60 mg of silica, a dose selectively toxic to macrophages, increased mortality due to MCMV infection. Transfer of syngeneic adult macrophages to suckling mice significantly increased their resistance to subsequent MCMV infection. Transfer of syngeneic, nonimmune adult lymphocytes to suckling mice also had a lesser but significant protective effect against subsequent MCMV challenge. In vitro infection of adult CBA/J and C57BL/6J macrophages with virulent and attenuated MCMV resulted in productive infection in only a small percentage of cells and recovery of very little virus from the extracellular fluid. Infection of CBA macrophages was no less productive than C57BL/6J nor was infection with virulent virus more productive than with attenuated virus. Histological examination of the livers of MCMV-infected CBA/J and C57BL/6J mice suggested that divergent cellular immune responses to infection might account for differences in susceptibility. It is postulated that the macrophage may facilitate the inductive phase of cellular immunity, one possible explanation for its demonstrated importance in host defenses against MCMV. PMID- 4140161 TI - Immunological studies of Brown recluse spider venom. AB - Polyacrylamide gel electrophoresis of Loxosceles reclusa venom demonstrated that only one of seven or eight major (plus three or four minor) protein components caused necrosis in guinea pig skin. Sephadex gel filtration separated the venom into three major peaks, the second peak of which contained the dermonecrotic activity. Hyperimmunization of rabbits with increasing doses of venom from L. reclusa produced potent precipitating antisera, and the rabbits became resistant to lesion development. Ouchterlony-type immunodiffusion and immunoelectrophoretic studies revealed six to seven distinct precipitation lines, one of which stained intensely for esterase activity. Immunohistochemical techniques failed to detect any protease, lipase, catalase, acid phosphatase, alkaline phosphatase, or amylase activity in the venom. The spreading activity of recluse spider venom in guinea pig skin was inhibited as much as 71% by antivenom. Venom preincubated with antivenom was unable to incite lesions in guinea pig skin. Passive immunization of guinea pigs 18 h before an injection of venom conferred venom resistance upon the animals. Local injections of antivenom immediately after intradermal injections of venom markedly reduced the dermal lesion. Heparin reduced the local and systemic effects of venom when preincubated with whole venom or when administered systemically before an intradermal injection of venom. Treatment of whole venom with the chelating agent ethylenediaminetetraacetate did not inhibit its necrotic activity. Transfer studies from a 24-h lesion indicated that the necrotic activity was localized and remained active in tissue for at least 24 h but not for 5 days. No lesions developed when high concentrations of venom were intradermally injected into the skin of sacrificed guinea pigs, indicating that an interaction of body constituents and venom is essential for the development of a lesion. PMID- 4140162 TI - Influence of culture medium on the glucosyl transferase- and dextran-binding capacity of Streptococcus mutans 6715 cells. AB - Growth of Streptococcus mutans 6715 in a medium containing trace amounts of sucrose or dextran promotes cell-associated glucosyl transferase activity and increases the dextran-binding capacity of the organisms. PMID- 4140163 TI - The etiology of Skid Rows in the United States. PMID- 4140164 TI - LSD-assisted psychotherapy in patients with terminal cancer. PMID- 4140165 TI - [Clinical significance of pharmacologic effects of roentgen contrast media]. PMID- 4140166 TI - Malignant tumours of the bile ducts. PMID- 4140167 TI - Human growth hormone. Characterization of plasma and pituitary components and application of a new radioreceptor assay. PMID- 4140168 TI - Subunits of human glycoprotein hormones. Their immunological and biological behavior. PMID- 4140169 TI - Experimental exophthalmos. Alterations of normal hormone-receptor interactions in the pathogenesis of a disease. PMID- 4140170 TI - The leukocyte nitroblue-tetrazolium reduction test. A rapid counting method. PMID- 4140171 TI - Sickle cell anemia: therapeutic considerations. PMID- 4140172 TI - Morphological changes of Mycobacterium leprae grown in mouse foot pads. PMID- 4140173 TI - The effect of methanol on granulocyte and horseradish peroxidase quantitatively studied in a film model system. PMID- 4140174 TI - Some histochemical reactions of mast cells of gerbils, hogs, armadillos and cats. PMID- 4140175 TI - Peroxisomes in the liver of the carp (Cyprinus carpio L.). Electron microscopic cytochemical and biochemical studies. PMID- 4140176 TI - Ultrastructural localization of catalase on ultracryotomic sections of mouse liver by ferritin-conjugated antibody technique. PMID- 4140177 TI - Digestibility of elastic fibers by elastase in semifine and fine sections as a function of fixation mode and embedding media. PMID- 4140178 TI - Formaldehyde-chloral hydrate as a fixative for mouse tissues for localisation of acid and alkaline phosphatases. PMID- 4140179 TI - A reply to comments by Scott (Histochemistry 39, 195--196, 1974). PMID- 4140180 TI - High-resolution scanning-densitometry of photographic negatives of human metaphase chromosomes. II. Feulgen-DNA measurements. PMID- 4140181 TI - High-resolution scanning-densitometry of photographic negatives of human metaphase chromosomes. I. Instrumentation. PMID- 4140182 TI - Breakage of DNA-membrane complex by bleomycin. PMID- 4140183 TI - Study on alpha-1 antitrypsin enzyme deficiency in adult cirrhosis. A preliminary communication. PMID- 4140184 TI - Curing action of sodium dodecyl sulfate on a Proteus mirabilis R+ strain. AB - Growth of Proteus mirabilis harboring R100-1 (fi(+)drd str(r)cml(r)tet(r)sul(r)) factors in Penassay broth containing sodium dodecyl sulfate (SDS) leads to the loss of all or part of the genetic elements in high frequencies. In media containing SDS at concentrations as low as 0.03%, both lysis of R(+) cells and elimination of the R factors occur at high frequencies. Appearance of drug susceptible cells in R(+) cultures occurs during the exponential phase of growth; however, the frequencies of susceptible cells increase substantially after the culture reaches the stationary phase. Reconstruction experiments, coupled with other observations, suggest that the major factor in altering the frequency of drug-susceptible variants is the greater resistance of the variants to the lytic action of SDS. This resistance correlates in most cases with the loss of the transfer functions in the resistance transfer factor. PMID- 4140185 TI - Bovine plasma kininogens. III. Structural comparison of high molecular weight and low molecular weight kininogens. PMID- 4140186 TI - Two-dimensional arrays and particles in negative staining preparations of fragmented human erythrocyte ghosts. PMID- 4140188 TI - A five-channel multimedia programmer constructed from surplus parts. PMID- 4140187 TI - Mechanism of action of ribonucleic acid-directed deoxyribonucleic acid polymerase. I. Transcription of globin messenger ribonucleic acid. PMID- 4140189 TI - The role of carbohydrate in platelet adhesion to foreign surfaces. PMID- 4140190 TI - Blood viscosity in patients with peripheral vascular diseases in the area of low shear rates. PMID- 4140191 TI - The high voltage electron microscope in biology. PMID- 4140192 TI - Effects of calcium-containing fixation solutions on cholinergic synaptic vesicles. AB - Calcium (Ca)-containing fixation solutions applied to slices of electric organ of the electric ray, Narcine brasiliensis, have been shown to have three distinct ultrastructural effects on cholinergic synaptic vesicles of the nerve terminals. (a) An electron-dense particle (EDS) is observed within the vesicle; the particle is seen in unosmicated, unstained tissues and can be removed from thin sections by Ca-chelating agents. It is concluded that the EDS represents Ca bound by the vesicle. It is suggested that the bound ATP of the vesicle provides anionic Ca binding sites. (b) The vesicle membrane tends to 'crinkle' or collapse depending on the concentration of the other components of the fixative solution. The 'crinkling' or collapse are largely reversed by a wash step in the absence of Ca. (c) The presence of Ca results in the appearance of a population of vesicles which form characteristic fusions or 'tight' junctions with the terminal membrane. This appears to be morphological evidence for the proposal, which has been frequently put forward, that Ca facilitates such a fusion before discharge of vesicle-bound transmitter. With the discovery that the use of Ca-containing fixatives leads to the demonstration of a subpopulation of synaptic vesicles fused to the terminal membrane, we are led to propose that this is the ultrastructural location of the newly synthesized acetylcholine which has been shown by others to be preferentially released by stimulation. PMID- 4140193 TI - The visualization of the photosynthetic coupling factor in embedded spinach chloroplasts. AB - Spinach chloroplast lamellae were stained with aqueous uranyl acetate immediately after glutaraldehyde-osmium fixation but before dehydration and embedding. Under these conditions, the lamellae are shown in thin sections to have 95-A x 115-A coupling factor particles on their surfaces. The particles can be seen only on the matrix side of nonopposed thylakoids, and are shown to occur on both stromal and granal lamellae, regardless of the organization of the lamellae into stacks. It is estimated that, in native, fully coupled chloroplast lamellae, there is on the average one coupling factor for every 500 chlorophyll molecules. The morphological appearance of the particles is not affected by a variety of buffers, by changes in illumination or temperature, or by alterations in the energy state of the membranes during preparation. The particles can be removed from the membranes with low concentrations of Na(2)EDTA, and the photophosphorylating activity of the membranes is concomitantly lost. Both the activity and the appearance of the particles can be restored to the membranes by rebinding EDTA-extracted coupling factors to the uncoupled membranes. PMID- 4140194 TI - Pinocytosis in fibroblasts. Quantitative studies in vitro. AB - Horseradish peroxidase (HRP) was used as a marker to determine the rate of ongoing pinocytosis in several fibroblast cell lines. The enzyme was interiorized in the fluid phase without evidence of adsorption to the cell surface. Cytochemical reaction product was not found on the cell surface and was visualized only within intracellular vesicles and granules. Uptake was directly proportional to the administered concentration of HRP and to the duration of exposure. The rate of HRP uptake was 0.0032-0.0035% of the administered load per 10(6) cells per hour for all cells studied with one exception: L cells, after reaching confluence, progressively increased their pinocytic activity two- to fourfold. After uptake of HRP, L cells inactivated HRP with a half-life of 6-8 h. Certain metabolic requirements of pinocytosis were then studied in detail in L cells. Raising the environmental temperature increased pinocytosis over a range of 2-38 degrees C. The Q(10) was 2.7 and the activation energy, 17.6 kcal/mol. Studies on the levels of cellular ATP in the presence of various metabolic inhibitors (fluoride, 2-desoxyglycose, azide, and cyanide) showed that L cells synthesized ATP by both glycolytic and respiratory pathways. A combination of a glycolytic and a respiratory inhibitor was needed to depress cellular ATP levels as well as pinocytic activity to 10-20% of control values, whereas drugs administered individually had only partial effects. In spite of the availability of an accurate quantitative assay for fluid and solute uptake, the function of pinocytosis in tissue culture cells remains unknown. PMID- 4140195 TI - Change of chromatin morphology during the cell cycle detected by means of automated image analysis. PMID- 4140196 TI - Specificity of heteroantisera to human acute leukemia-associated antigens. AB - Antisera have been raised to human leukemic blast cells from individual patients in mice rendered tolerant with cyclophosphamide to remission leukocytes from the same individual. 10 antisera were raised against acute myelogenous leukemia (AML) cells and 5 antisera were raised against acute lymphoblastic leukemia (ALL) cells. Antisera to AML cells were absorbed with ALL cells, and antisera to ALL cells were absorbed with AML cells. Unabsorbed and absorbed antisera as well as antisera raised in nontolerant mice were tested for cytotoxicity against various cells of a panel containing myeloblasts from 35 patients with AML, lymphoblasts from 7 patients with ALL, myeloblasts from 7 patients with chronic myelogenous leukemia (CML) in blast crisis, peripheral blood leukocytes from 12 patients with acute leukemia in remission and 30 nonleukemic patients, and nucleated bone marrow cells from 10 nonleukemic patients. Unabsorbed antisera to AML or ALL cells raised in tolerant mice were highly cytotoxic to leukemic blasts cells but significantly less cytotoxic to remission and control cells. Antisera to AML cells absorbed with ALL cells retained measurable cytotoxicity against AML cells but were not cytotoxic to ALL cells or control cells. Similarly, antisera to ALL cells absorbed with AML cells retained significant cytotoxicity only to ALL cells. Control antisera raised in nontolerant mice were cytotoxic to all cells tested. Although species specific, histocompatibility, differentiation, maturation, and cell cycle-associated antigens may be responsible in part for the cytotoxic activity of the unabsorbed antisera, the absorbed antisera are probably detecting antigens specific for their leukemic cell type. PMID- 4140197 TI - Immunochemical studies of plasma kallikrein. AB - A monospecific antibody against human plasma kallikrein has been prepared in rabbits with kallikrein further purified to remove gamma globulins. The antisera produced contained antikallikrein and also anti-IgG, in spite of only 8% contamination of kallikrein preparation with IgG. The latter antibody was removed by adsorption of antisera with either Fletcher factor-deficient plasma or with purified IgG. Both kallikrein and prekallikrein (in plasma) cross-react with the antibody with no apparent difference between the precipitation arcs developed during immunoelectrophoresis and no significant difference in reactivity when quantified by radial immunodiffusion. Kallikrein antibody partially inhibits the esterolytic and fully inhibits the proteolytic activity of kallikrein. In addition, the antibody inhibits the activation of prekallikrein, as measured by esterase or kinin release. The magnitude of the inhibition is related to the molecular weight of the activator used. Thus, for the four activators tested, the greatest inhibition is observed with kaolin and factor XII(A), while large activator and the low molecular weight prekallikrein activators are less inhibited. With the kallikrein antibody, the incubation of kallikrein with either plasma or partially purified C1 esterase inactivator results in a new precipitin arc, as detected by immunoelectrophoresis. This finding provides physical evidence for the interaction of the enzyme and inhibitor. No new arc could be demonstrated between kallikrein and alpha(2)-macroglobulin, or alpha(1) antitrypsin, although the concentration of free kallikrein antigen decreases after interaction with the former inhibitor. By radial immunodiffusion, plasma from healthy individuals contained 103+/-13 mug/ml prekallikrein antigen. Although in mild liver disease, functional and immunologic kallikrein are proportionally depressed, the levels of prekallikrein antigen in plasma samples from patients with severe liver disease remains 40% of normal, while the functional kallikrein activity was about 8%. These observations suggest that the livers of these patients have synthesized a proenzyme that cannot be converted to active kallikrein. PMID- 4140198 TI - The "no-reflow" phenomenon after temporary coronary occlusion in the dog. AB - The role of microvascular damage in the genesis of the "no-reflow" phenomenon was investigated in the left ventricular myocardium of dogs subjected to temporary occlusions of a major coronary artery for 40 and 90 min. Intravenous carbon black or thioflavin S (a fluorescent vital stain for endothelium) were used to demonstrate the distribution of coronary arterial flow in control and damaged myocardium. These tracers were injected simultaneously with release of the coronary occlusion or after 5 or 20 min of reflow of coronary arterial blood. After 40 min of ischemia plus arterial reperfusion, usually the tracers were evenly distributed throughout the damaged tissue at each time of reperfusion. On the other hand, when reflow was allowed after 90 min of ischemia, portions of the inner half of damaged myocardium were not penetrated by the tracers. Electron microscopic study of this poorly perfused tissue revealed severe capillary damage; endothelial cells with large intraluminal protrusions and decreased pinocytic vesicles were common. Also, occasional intraluminal fibrin thrombi were noted, as well as extravascular fibrin deposits and erythrocytes. Myocardial cells were swollen in both poorly perfused and well-perfused irreversibly injured tissue. Contraction bands and mitochondrial Ca(2+) accumulation were prominent features of irreversible injury with reflow at 40 min but were not noted after 90 min of ischemia in areas with poor perfusion. These results suggest that 40 min of ischemia were tolerated by the capillary bed of the dog heart without serious capillary damage or perfusion defects, but that 90 min of ischemic injury was associated with the "no-reflow" phenomenon, i.e., failure to achieve uniform reperfusion. This failure of reflow was associated with extensive capillary damage and myocardial cell swelling. Death of severely ischemic myocardial cells in this model occurs before the onset of capillary damage and the no-reflow phenomenon. PMID- 4140199 TI - Phenformin therapy of chemical diabetes. PMID- 4140200 TI - Anatomical analysis of pupillary reflex pathways in the rhesus monkey. PMID- 4140201 TI - Practice related exercises--an approach to teaching preclinical technique. PMID- 4140202 TI - Letter: Further risk with bleomycin. PMID- 4140204 TI - ACtivity stain for the detection of L-asparaginase- anti-L-asparaginase complexes in agar. PMID- 4140203 TI - Solid tumor chemotherapy: new drugs and horizons. PMID- 4140205 TI - The simultaneous detection of two protein antigens in lymphoid tissues by combining immunofluorescence and autoradiography. PMID- 4140206 TI - The simultaneous detection of 3H- and 14C-labelled cells by double-layer autoradiography. PMID- 4140208 TI - [Treatment of esophageal cancer with antineoplastic agents in conjunction with surgery]. PMID- 4140207 TI - Morphologic, biologic, and cytochemical analysis of intracytoplasmic particles found in cultured fibroblasts from patients with systemic lupus erythematosus. PMID- 4140209 TI - [Diagnosis and treatment based on the characteristics of esophageal cancer]. PMID- 4140210 TI - [Cell kinetic study on the effects of cancer chemotherapeutic agents on primary culture cells from human oral mucosa (author's transl)]. PMID- 4140211 TI - Cardiac surgery in early infancy, updated. PMID- 4140212 TI - Localization of rhodomelanochrome in melanosomes of leaf frogs. PMID- 4140213 TI - Revertants of mouse cells transformed by murine sarcoma virus: flat variants without a rescuable sarcoma virus from a clone of BALB/3T3 transformed by Kirsten MSV. PMID- 4140214 TI - 14 and 6 Per second positive spiking. Developmental and clinical correlates in psychiatric patients and their siblings. PMID- 4140215 TI - The P2 protein of bovine root myelin: isolation and some clinical and immunological properties. PMID- 4140216 TI - Axonal transport and turnover of proline- and leucine-labeled protein in the goldfish visual system. PMID- 4140217 TI - Studies of axon permeability utilizing axoplasm extrusion techniques with single isolated axons from the circumesophageal connectives of Homarus americanus. PMID- 4140218 TI - The extent of axoplasmic transport during development, determined by migration of various radioactively-labelled materials. PMID- 4140219 TI - Proteolytic enzymes and experimental demyelination in the rat and monkey. PMID- 4140220 TI - The isolation and properties of large basic peptides from bovine spinal cord. PMID- 4140221 TI - The fine structural differences in human muscle fiber types based on peroxidatic activity. PMID- 4140222 TI - Adrenaline and noradrenaline cells in the adrenal medulla of the hamster: a morphological study of their innervation. PMID- 4140223 TI - The zinc-iodide-osmium reactive sites in the sensory epithelia of the frog labyrinth. PMID- 4140224 TI - External version in the rhesus negative woman. PMID- 4140225 TI - Maternal serum sialomucins during and after normal pregnancy. PMID- 4140226 TI - [Laryngeal neoplasms]. PMID- 4140227 TI - Antibodies against endocardium, vascular structures, and interstitium of striated muscle that cross-react with T. cruzi and T. rhodesiense. PMID- 4140228 TI - Iron gallein as a substitute for iron hematoxylin in parasitological staining. PMID- 4140229 TI - Metabolic and ionic requirements for the axoplasmic transport of dopamine beta hydroxylase. AB - 1. Metabolic and ionic requirements for the intra-axonal transport of dopamine beta-hydroxylase (DBH) were investigated in the cat hypogastric nerve-inferior mesenteric ganglion preparation in vitro by monitoring the enzyme accumulation above a crush, 2-2.5 cm distal to the ganglion.2. DBH accumulation in the proximal segment immediately above the crush increased linearly up to 6 h, during incubation in normal Krebs solution at 37 degrees C. The rate of transport of the enzyme was about 4 mm/h.3. Removal of the ganglion, electrical stimulation or reserpine pretreatment (1-6 days before the experiment) did not modify the rate of DBH accumulation.4. Anoxia and glucose deprivation, singly, did not affect accumulation of DBH; however, the combined treatment of anoxia plus glucose deprivation, or dinitrophenol plus glucose deprivation, very markedly interfered with accumulation.5. Removal of sodium or potassium from Krebs solution markedly inhibited the transport of DBH. Preincubation of the nerve in a high-calcium Krebs solution at 4 degrees C, and then reincubation at 37 degrees C, prevented the enzyme accumulation.6. N-ethylmaleimide, ouabain and oligomycin markedly inhibited the transport of DBH.7. The results suggest that transport of DBH, and therefore of noradrenaline storage vesicles, within the hypogastic nerve is dependent on metabolic energy derived from either glycolysis or oxidative phosphorylation. It is also suggested that the sodium-potassium-activated ATPase may play an important role in the intra-axonal transport of storage vesicles. PMID- 4140230 TI - The movement of optically detectable organelles in myelinated axons of Xenopus laevis. AB - 1. Intra-axonal organelles were detected by darkfield and Nomarski microscopy in isolated myelinated nerve fibres from Xenopus laevis. Nerve fibres from the 8th spinal roots, the sciatic nerve, and identified motor and sensory axons from other hind limb nerves were used. The movement of the organelles was recorded either on motion picture film or by noting the times at which they crossed the lines of an ocular grid.2. Three groups of organelles were detected in all fibres. A group of particles with round profiles 0.2-0.5 mum in diameter moved somatopetally. Another group of round particles moved somatofugally. The ratio of the number of somatopetally travelling particles to the number of somatofugally travelling particles was about 10:1. The third group of organelles consisted of rod-shaped bodies about 0.2-0.3 mum in diameter and 1-8 mum in length; these were usually stationary.3. All the round particles appeared to move independently of each other with a saltatory motion. The somatopetally and somatofugally travelling particles had statistically different mean velocities of 0.98 and 1.32 mum/sec respectively.4. Round particles often crossed the node of Ranvier with no appreciable change in velocity. Some, however, were temporarily arrested at the entrance to the node.5. While the rod-shaped organelles were usually stationary, they occasionally moved rapidly lengthwise for distances of up to 10 mum. Rarely a rod-shaped organelle exhibited a continuous saltatory motion.6. Round particles often travelled in either direction along the edge of rod-shaped organelles. One rod was observed to move along the path previously taken by a round particle.7. The findings are discussed with respect to (a) the normality of the preparations, (b) the numbers of particles travelling in each direction, (c) the nature of the organelles, and (d) the mechanisms underlying the motion.8. We suggest that particles move along microtubules which have specific directionalities and particle affinities. The microtubules are in bundles and are closely associated with rod-shaped mitochondria. PMID- 4140231 TI - [Semantics of the radiographic picture. New form of picture storage]. PMID- 4140232 TI - [Radiotherapy of rectal cancers. Apropos of surgical treatment for rectal cancer]. PMID- 4140233 TI - [Radiotherapy of rectal cancers. Radiotherapy of inoperable and recurring rectal cancers]. PMID- 4140234 TI - [Radiotherapy of rectal cancers. Apropos of 100 cases]. PMID- 4140235 TI - The diagnostic value of detecting eosinophilia of nasal secretions in allergic rhinitis. AB - Nasal mucus eosinophilia was found in 92 per cent of adults with active hay fever. After an initial period of gaining experience in the method of collecting mucus, this was found to be a simple cheap method of demonstating an allergic component in the genesis of rhinitis. This test could be employed for detecting the relationship of allergic factors to chronic respiratory tract disease in childhood and in adults. PMID- 4140236 TI - Interrupted aortic arch and ventricular septal defect: palliation in a neonate. PMID- 4140237 TI - Studies on specificity of cell-mediated immunity to human tumors. PMID- 4140238 TI - Effect of antigen density on complement-mediated lysis, T-cell-mediated killing, and antigenic modulation. PMID- 4140239 TI - Effect of immunoregulatory alpha-globulin on in vitro proliferative response of immune rat lymphocytes to syngeneic Gross virus-induced lymphoma. PMID- 4140240 TI - Recovery of murine xenotropic type-C virus from C57L mice. PMID- 4140241 TI - The nephrotic syndrome of childhood in Thailand. Histological, immunohistological and clinical correlations. PMID- 4140242 TI - Advanced carcinoma of bladder: treatment using hypogastric artery infusion with 5 fluorouracil, either as a single agent or in combination with bleomycin or adriamycin and supervoltage radiation. PMID- 4140243 TI - Fibroadenoma of the urachus. PMID- 4140244 TI - Letter: Gammopathy and carcinoma. PMID- 4140245 TI - [Application of minocycline for intravenous drip in urological field (author's transl)]. PMID- 4140246 TI - [Laboratory and clinical studies on amikacin (BB-K8), a new semisynthetic aminoglycoside (author's transl)]. PMID- 4140247 TI - Study on tuberactinomycin-N. I. In vitro Antibacterial activity of TUM-N on Tubercle bacilli isolated from patients. PMID- 4140248 TI - [Comparison of ampicillin-dicloxacillin (HI-56) with ampicillin against complex urinary tract infections (author's transl)]. PMID- 4140249 TI - [Clinical effect of ampicillin-dicloxacillin combination in chronic complicated urinary tract infections (author's transl)]. PMID- 4140250 TI - The incidence of myocardial abnormalities in man related to the level of ethanol consumption. A proposal of a diagnostic criterion of alcoholic cardiomyopathy. PMID- 4140251 TI - [Etiology and classification of hypothyroidism]. PMID- 4140252 TI - Tolerance induction in mice by continuous infusion of antigens. PMID- 4140253 TI - Persistent Masugi nephritis induced in rats in spite of the suppression of host antibody responses against the heterologous nephrotoxic antibodies. PMID- 4140254 TI - The management of extrahepatic bile duct carcinoma. PMID- 4140256 TI - Alpha-fetoprotein in the treatment of primary liver cancer. PMID- 4140255 TI - Changes in liver function after hepatic dearterialization in man. PMID- 4140257 TI - [An immunological study of plasminogen activator activity in the bladder (author's transl)]. PMID- 4140258 TI - [On the question of rosacea especially of rosacea keratitis (author's transl)]. PMID- 4140259 TI - [Complete destruction of the orbit by a malignant tumor (author's transl)]. PMID- 4140260 TI - Dietary cadmium and enteropathy in the Japanese quail: histochemical and ultrastructural studies. PMID- 4140261 TI - [The use of thermoanalytic methods in connective tissue research. 1. The composition of cartilage and tendon tissues under physiologic conditions]. PMID- 4140262 TI - [Thermoanalytic studies in connective tissue research. II. Changes in the structure of cartilage and tendon tissues under pathologic conditions]. PMID- 4140263 TI - The viability of parenchymal liver cells isolated from young and old rats. PMID- 4140264 TI - The effects of dimethylaminoethyl p-chlorophenoxyacetate on spinal ganglia neurons and satellite cells in culture. Mitochondrial changes in the aging neurons. An electron microscope study. PMID- 4140265 TI - Detection of recurrence of large-bowel carcinoma by radioimmunoassay of circulating carcinoembryonic antigen (C.E.A.). AB - The usefulness and limitations of the carcinoembryonic antigen (C.E.A.) radioimmunoassay for the evaluation of tumour resection and for the detection of tumour relapse were studied in patients with large-bowel carcinoma. The level of plasma-C.E.A. was determined before any treatment in a group of 101 patients with histologically proven adenocarcinoma of the colon and rectum. 71% of all patients and 63% of cases with localised tumour (Dukes A and B) had a preoperative C.E.A. value of 5 ng. per ml. or higher. This limit was reached by only 1 of 90 apparently healthy, non-smoking blood-donors. Among 45 patients for whom a complete tumour resection was reported, all patients except 5 showed a drop of C.E.A. to normal values after surgery. The 5 patients whose C.E.A. did not fall to below 5 ng. per ml. showed a subsequent rise in C.E.A. level and were all found later to have a tumour relapse. The results indicate that an incomplete drop of circulating C.E.A. level one month after surgery has a bad prognostic significance. 22 of these patients were followed up by repeated C.E.A. radioimmunoassay for several months after surgery. 8 showed a progressive increase in C.E.A. levels preceding clinical diagnosis of tumour relapse by two to ten months. 6 other patients showed a moderate increase in C.E.A. levels, suggesting a tumour relapse not yet clinically detectable. The remaining 8 patients showed no increase in C.E.A. level above 5 ng. per ml. and no clinical symptoms of relapse. The results demonstrate that relapses of colon and rectum carcinoma can be detected by increased C.E.A. levels months before the appearance of any clinical evidence. PMID- 4140266 TI - Natural history of phenylketonuria and influence of early treatment. AB - This study describes the intellectual development of twenty-eight sibling pairs with phenylketonuria in which the index case presented because of retarded development. In twelve pairs (group I) the "second" sibling was born subsequently, and in sixteen (group II) there was a second sibling already in the family at the time of diagnosis of the index case. The intellectual outcome of the second siblings of group II suggests that approximately 1 in 6 or 7 patients with untreated classical phenylketonuria achieves an I.Q. above 70, although with evidence of intellectual impairment. The highly significant difference in intellectual outcome between the early treated second siblings of group I and the late or untreated second siblings of group II demonstrates the beneficial effect of early treatment on the intelligence of affected children. PMID- 4140267 TI - Ascorbic acid supplementation in the treatment of pressure-sores. AB - In a prospective double-blind controlled trial the effect of large doses of ascorbic acid on the healing of pressure-sores has been assessed. 20 surgical patients were studied, the pressure areas being assessed by serial photography and ulcer tracings. The mean ascorbic-acid levels in treated and non-treated groups one month after the start of treatment were 65.6 and 25.8 mug per 10-8 white blood-cells. In the group treated with ascorbic acid there was a mean reduction in pressure-sore area of 84% after one month compared with 42.7% in the placebo group. These findings are statistically significant (P less than 0.005) and suggest that ascorbic acid may accelerate the healing of pressure-sores. PMID- 4140268 TI - Vagal control of glucagon release in man. AB - A significant fall in fasting plasmapancreatic-glucagon was produced by injection of atropine. After arginine infusion atropine reduced the normal rise of glucagon by 33% and glucose by 40%. Eleven patients studied during insulin hypoglycaemia after a selective vagotomy showed a peak rise in plasma-glucagon of 173 pg. per ml., which was not significantly different from the glucagon rise in ten preoperative controls (168 pg. per ml.). The glucagon response to insulin hypoglycaemia (81 pg. per ml.) in a matched group of ten patients with truncal vagotomy was significantly less than after selective vagotomy. This evidence of parasympathetic control of the alpha cell accords with morphological and laboratory-animal findings. Maintenance of normal glucagon release after selective vagotomy favours the use of this operation rather than the cruder truncal vagotomy. PMID- 4140270 TI - Effect of glycerophosphate on lithogenic bile. A new approach to treatment of cholelithiasis. AB - Previous studies in animals showed a twofold increase of bile-phospholipids when glycerophosphate, a precursor of phospholipids, was incorporated in chow diet. The present study evaluates the effect of short-term administration of beta glycerophosphate on bile composition in patients with lithogenic bile. 10 patients with lithogenic bile were selected for study; 9 had cholelithiasis. Fasting hepatic and gallbladder bile before and after treatment with beta glycerophosphate (6 g. daily for six days) was analysed for molar ratios of cholesterol (Ch.), total bile-salts (B.S.), and total phospholipids (P.L.). The molar ratios of Ch. divided by B.S. + P.L. in hepatic bile decreased in 9 of the 10 patients (P less than 0.01). Thus in all but 1 of the 10 patients the hepatic bile became less lithogenic. This observation was confirmed by plotting the molar percentages on triangular coordinates. The results suggest no change in cholesterol concentrations but an increase of phospholipid and bile-salt concentrations. The composition of the gallbladder bile did not change. These preliminary studies indicate that beta-glycerophosphate should be evaluated as a potential new therapeutic agent for dissolution of cholesterol gallstones in man. PMID- 4140269 TI - Changes in cortisol metabolism following rifampicin therapy. AB - A patient with Addison's disease required increased corticosteroid dosage whilst receiving rifampicin. The pharmacological half-life of cortisol was reduced, but returned to normal when rifampicin was stopped. Cortisolproduction rates in four patients with pulmonary tuberculosis rose during treatment with rifampicin, as did urinary D-glucaric-acid excretion, an index of liver microsomal-enzyme activity. The alteration of the corticosteroid requirement in the patient with Addison's disease and the elevation of the cortisol-production rates were attributed to increased cortisol catabolism following hepatic macrosomal-enzyme induction by rifampicin. PMID- 4140271 TI - Radioimmunoassay of cannabinoids in blood and urine. AB - A radioimmunoassay (R.I.A.), using a sheep antiserum and 3-H-T.H.C., has been developed for the measurement of tetrahydrocannabinol (T.H.C.) in plasma and urine. The antiserum cross-reacts with T.H.C. metabolites, but nevertheless possesses sufficient group specificity and sensitivity to permit measurement of cannabinoids in plasma and urine of animals and volunteers following the administration of pure T.H.C. Subjective effects experienced by the volunteers seemed to correlate with plasma-T.H.C. levels. The examination of random plasma urine samples collected from patients attending a drug-addiction clinic revealed the presence of measurable amounts of cannabinoids in several of them. PMID- 4140272 TI - Simplified method for diagnosis of genital and ocular infections with Chlamydia. AB - The diagnosis of infections with chlamydia related to the trachoma agent is best confirmed by isolation of the organism in tissue-culture. A simplified technique using conventional monolayers of McCoy cells can be used as an alternative to current methods involving heavily irradiated cells and appears to be of reasonable sensitivity. Chlamydial infection was confirmed in 38/190 females attending venereal clinics, in 22/35 patients with hypertrophic cervical erosions, and in 7/18 infants with ophthalmia neonatorum. PMID- 4140273 TI - Pathogenesis of lipoid nephrosis: a disorder of T-cell function. AB - Clinical observations suggest that lipoid nephrosis is produced by a systemic abnormality of T-cell function resulting in the secretion of a circulating chemical mediator toxic to an immunologically innocent glomerular basement membrane. The lack of evidence of a humoral antibody response, remission induced by measles which modifies cell-mediated immunity, the therapeutic benefits of steroids and cyclophosphamide which also abate cell-mediated responses, and the occurrence of this syndrome in Hodgkin's disease support this hypothesis. The susceptibility of untreated patients to pneumococcal infections may be of primary or secondary pathogenetic importance. Taken together, the data suggest that this syndrome is a clinical expression of a self-limited primary immune-deficiency disease. PMID- 4140274 TI - Editorial: Confinement of the poxvirus. PMID- 4140275 TI - Editorial: Electrical stimulation of the brain. PMID- 4140276 TI - Editorial: Long-term intravenous feeding. PMID- 4140277 TI - Editorial: Thallium. PMID- 4140278 TI - Editorial: Grey-scale ultrasonography. PMID- 4140279 TI - Training of medical teachers. AB - The need for teacher training in the health professions and the shortcomings of the usual methods of involving teachers in teaching strategies are discussed. An outline of a course employing a workshop method to overcome some of the shortcomings is given, based on the four years' experience of the course held at King's College Hospital Medical School. PMID- 4140280 TI - Training teachers of general practice. PMID- 4140281 TI - Teacher training for medical schools in Africa. AB - Though the problem areas of medical education in Africa have been defined and steps have been taken to attack them, notably by preparing teaching staff as agents of change and by opening teacher-training centres, progress cannot be otherwise than slow. PMID- 4140282 TI - Educational assistants. AB - Certain needs of medical education might be met through a team approach by which clinical teachers, in particular, can save time and effort in the planning, implementation, and assessment of education. This could be achieved through the help of educational consultants whose relationship to the teachers, as well as their responsibilities and training, are here discussed. PMID- 4140283 TI - Environmental stress and thyrotoxicosis. Absence of association. AB - The incidence of treated thyrotoxicosis in Northern Ireland has been estimated by the technique of "therapeutic auditing" for the periods (a) three years preceeding the start of the present civil unrest and (b) the ensuing three years. No change in incidence was found, which supports the concept that environmental stress is not important in the pathogenesis of this disease. PMID- 4140284 TI - Pseudomonas aeruginosa in hospital sinks. AB - Pseudomonas aeruginosa was isolated from sink waste-traps in 27 of 116 (23.3%) samples from a large general hospital and from 19 of 47 (40.4%) samples from a burns unit at another hospital. Smaller proportions of samples from sink outlets and surfaces of basins yielded Ps. aeruginosa. A waste-trap heater ('Econa') used twice daily for fifteen minutes reduced the isolations of Ps. oeruginosa from waste-traps to a very low level; isolations of other organisms were also reduced, though to a smaller extent. Despite the continuing high frequency of Ps. aeruginosa in sinks and some other moist hospital sites, Ps. aeruginosa infections were infrequent in the general hospital and had been greatly reduced by the successful use of various prophylactic measures in the burns unit. PMID- 4140285 TI - Letter: Blood fractions for haemophilia. PMID- 4140286 TI - Letter: Medical nemesis. PMID- 4140287 TI - Letter: "Wild white" viruses and smallpox. PMID- 4140289 TI - Letter: Classification of non-Hodgkin's lymphomas. PMID- 4140288 TI - Letter: Evaluation of laboratory testing. PMID- 4140290 TI - Letter: Origin of malignant lymphomas. PMID- 4140291 TI - Letter: Grey-scale ultrasonography in the investigation of obstructive jaundice. PMID- 4140292 TI - Letter: Manipulating the patient. PMID- 4140293 TI - Letter: Hyposplenism and ulcerative colitis. PMID- 4140294 TI - Letter: Myopathies: the neurogenic hypothesis. PMID- 4140295 TI - Letter: Carcinogenic potential of magnesium deficiency. PMID- 4140296 TI - Letter: Peak-flow meter v. peak-flow gauge. PMID- 4140297 TI - Letter: Trauma and cancer. PMID- 4140298 TI - Letter: Cadaver-kidney donation. PMID- 4140299 TI - Letter: Treatment of anorexia nervosa by levodopa. PMID- 4140300 TI - Letter: Proportional mortality among vinyl-chloride workers. PMID- 4140301 TI - Letter: "Localised hypertrophic neuropathy" and hypertrophic polyneuropathy. PMID- 4140302 TI - Letter: Sterile operating-theatres. PMID- 4140303 TI - Letter: Reye's syndrome or not? PMID- 4140305 TI - Letter: Weather and myasthenic fatigue. PMID- 4140304 TI - Letter: Fenfluramine and dreaming. PMID- 4140306 TI - Letter: Lithium, Ebstein's anomaly, and other congenital heart defects. PMID- 4140307 TI - Letter: Transplacental lithium poisoning. PMID- 4140308 TI - Letter: Protein requirement. PMID- 4140309 TI - Letter: Autoinhibition of P.H.A. response by chronic-lymphocytic-leukaemia serum. PMID- 4140310 TI - Letter: Infantile cataract and galactose metabolism. PMID- 4140311 TI - Letter: Methylprostaglandin e2 methyl ester and gastric-ulcer healing. PMID- 4140312 TI - Letter: Testosterone cream: use or abuse? PMID- 4140313 TI - Letter: Microbial-antigen detection. PMID- 4140314 TI - Letter: Diagnosis of insulinomas by suppression tests. PMID- 4140315 TI - Letter: Nature of nuclear projections in adenocarcinoma of the breast. PMID- 4140316 TI - Letter: Storage and transport of serum for prolactin radioimmunoassay. PMID- 4140317 TI - Letter: Anti-epileptic drugs and failure of oral contraceptives. PMID- 4140318 TI - Letter: Labelled leucocytes in thrombi. PMID- 4140319 TI - Letter: Oxytocin and neonatal jaundice. PMID- 4140320 TI - Letter: Iron and resistance to infection. PMID- 4140322 TI - Letter: Dermatoglyphic nomogram in diagnosis of trisomy 21. PMID- 4140321 TI - Letter: Paramyxovirus-like structures in Goodpasture's syndrome. PMID- 4140323 TI - Robert Cruickshank. PMID- 4140324 TI - Edward Falkner Hill. PMID- 4140325 TI - John Nathaniel Cumings. PMID- 4140326 TI - William Johnston. PMID- 4140327 TI - Chemoimmunotherapy of adult acute leukaemia. Prolongation of remission in myeloblastic leukaemia with B.C.G. PMID- 4140328 TI - Prednisone in Duchenne muscular dystrophy. PMID- 4140329 TI - Paget's bone disease: response to human calcitonin in patients resistant to salmon calcitonin. PMID- 4140330 TI - Impairment of folate absorption by systemic bacterial infections. PMID- 4140331 TI - Hypertonicity of the cricopharyngeal sphincter: A cause of globus sensation. PMID- 4140332 TI - Increased plasma levels of 15-keto-13,14-dihydro-prostaglandin F2X after allergen provoked asthma in man. PMID- 4140333 TI - Availability of three antibiotics after intramuscular injection into thigh and buttock. PMID- 4140335 TI - Editorial: Anaemia during pregnancy. PMID- 4140334 TI - Autoimmune mechanisms in human vascular disease. PMID- 4140337 TI - Editorial: Carry on talking. PMID- 4140336 TI - Editorial: Predisposition to thrombosis. PMID- 4140338 TI - Editorial: Chemoprophylaxis of meningococcal infections. PMID- 4140339 TI - Editorial: Burn toxin. PMID- 4140340 TI - Editorial: Acute arsine poisoning. PMID- 4140341 TI - Editorial: Students as patients. PMID- 4140342 TI - Multiphasic screening. PMID- 4140343 TI - Biochemistry of well populations. PMID- 4140344 TI - Biochemical profiles for hospital patients. PMID- 4140345 TI - Teaching geriatric medicine. PMID- 4140346 TI - Letter: Diet and geographical distribution of multiple sclerosis. PMID- 4140347 TI - Letter: Aetiopathogenesis of multiple sclerosis. PMID- 4140349 TI - Letter: The consultants' contract. PMID- 4140348 TI - Letter: Enzyme antidote for experimental cyanide poisoning. PMID- 4140350 TI - Letter: Doctors and social workers.,. PMID- 4140351 TI - Letter: Sanctions and the National Health Service. PMID- 4140352 TI - Letter: The nurse in the community. PMID- 4140353 TI - Letter: Detection of breast cancer. PMID- 4140354 TI - Letter: Screening for cardiovascular diseases. PMID- 4140355 TI - Letter: Screening for spina bifida. PMID- 4140356 TI - Letter: Antibodies against thyroid cells in Yersinia enterocolitica infection. PMID- 4140357 TI - Letter: Monoamine-oxidase and migraine. PMID- 4140358 TI - Letter: Effects of hysterectomy. PMID- 4140359 TI - Letter: Mortality and natural fluoride content of drinking-water. PMID- 4140360 TI - Letter: Malignant hyperthermia: a human stress syndrome? PMID- 4140361 TI - Letter: Inadequate mothers. PMID- 4140362 TI - Letter: Artificial kidney and artificial liver. PMID- 4140363 TI - Letter: Blood fractions for haemophilia. PMID- 4140364 TI - Letter: Localisation of phaeochromocytoma. PMID- 4140365 TI - Letter: Recovery after minor head injury. PMID- 4140366 TI - Letter: Fetal lung maturation in toxaemia and oestrogen therapy in management of respiratory distress syndrome. PMID- 4140367 TI - Letter: Follow-up in tuberculosis. PMID- 4140368 TI - Letter: Myelopathy in cervical spondylosis. PMID- 4140369 TI - Letter: Divalent cations in predicting antidepressant response to lithium. PMID- 4140370 TI - Letter: Influence of age on neurohormonal receptors. PMID- 4140371 TI - Letter: A time to be born. PMID- 4140372 TI - Letter: Time dimension of the gene. PMID- 4140373 TI - Letter: Potassium supplements. PMID- 4140374 TI - Letter: Health of plutonium workers. PMID- 4140375 TI - Letter: Monoamniotic twins. PMID- 4140376 TI - Letter: A simple non-invasive technique for measuring cardiac contractility. PMID- 4140377 TI - Letter: Diagnostic accuracy of vaginal smears. PMID- 4140378 TI - Letter: Death-rates from diabetes. PMID- 4140379 TI - Letter: Doctors and smoking. PMID- 4140380 TI - Letter: Duplication of 21 or 8-21 translocation in acute leukaemia. PMID- 4140381 TI - Letter: Plasmapheresis in rhesus isoimmunisation. PMID- 4140382 TI - Letter: Lithium and M.R.I.H. in tardive dyskinesia. PMID- 4140383 TI - Letter: Fetal adiposity in infants of diabetic mothers. PMID- 4140384 TI - Letter: Treatment of malignant melanoma. PMID- 4140386 TI - Letter: Treatment of enuresis. PMID- 4140385 TI - Letter: Plasma-diazepam levels following intramuscular injection by nurses and doctors. PMID- 4140387 TI - Letter: Thrombocytopenia after intralipid infusion in a neonate. PMID- 4140388 TI - Letter: Familial Hodgkin's disease. PMID- 4140389 TI - Letter: Serum-gentamicin. PMID- 4140390 TI - Obituary: Douglas Cameron Lavender. PMID- 4140391 TI - Radionuclide brain scanning in investigation of late-onset seizures. PMID- 4140392 TI - Mortality in adults and trace elements in water. PMID- 4140393 TI - Therapeutic effectiveness of oral testosterone. PMID- 4140394 TI - Mortality from malignant disease in patients with asthma. PMID- 4140395 TI - Sclerosing peritonitis, an unusual reaction to a beta-adrenergic-blocking drug (practolol). PMID- 4140396 TI - In-vitro interactions between antitumour antibodies and anti-antibodies in malignancy. PMID- 4140397 TI - Transfusion of plasma-protein fraction and renal-allograft rejection. PMID- 4140398 TI - Distribution of cerebral activity in chronic schizophrenia. PMID- 4140399 TI - A device to prevent disconnection at 3-way tap junctions. PMID- 4140400 TI - Editorial: Are sex hormones teratogenic? PMID- 4140401 TI - Editorial: Treatment of acromegaly. PMID- 4140402 TI - Editorial: The giraffe's parameter. PMID- 4140404 TI - Editorial: Epidemic giardiasis. PMID- 4140403 TI - Editorial: Evicting the mite. PMID- 4140405 TI - Editorial: The Doctor Fox effect. PMID- 4140406 TI - Taking stock. PMID- 4140407 TI - Congenital and infantile neoplasia of the kidney. PMID- 4140408 TI - Outbreak of psychosomatic illness at a rural elementary school. PMID- 4140409 TI - Animal models in cancer research. PMID- 4140410 TI - Letter: Protein requirement. PMID- 4140411 TI - Letter: Units of energy in nutrition. PMID- 4140412 TI - Letter: Diabetes, HL-A antigens, and congenital rubella. PMID- 4140413 TI - Letter: Diabetes and virus infection. PMID- 4140414 TI - Letter: Incidence of diabetes in children. PMID- 4140415 TI - Letter: Television in the ward. PMID- 4140416 TI - Letter: Tight gloves. PMID- 4140417 TI - Letter: Ovulation stimulation and defects of neural-tube closure. PMID- 4140418 TI - Letter: Prospective diagnosis of spina bifida. PMID- 4140419 TI - Letter: Anencephaly, subfertility, and abortion. PMID- 4140420 TI - Letter: Diet and multiple sclerosis. PMID- 4140421 TI - Letter: Effectiveness of hepatitis-B immune globulin in haemodialysis patients. PMID- 4140422 TI - Letter: Dane particles in cord blood. PMID- 4140423 TI - Letter: HBsAg subtype and chronic glomerulonephritis. PMID- 4140424 TI - Letter: Risk of transfusing blood containing anti-HBs. PMID- 4140425 TI - Letter: Absence of HBsAg and anti-HBs in spinal fluid. PMID- 4140426 TI - Letter: Reaction to phenoxybenzamine. PMID- 4140427 TI - Letter: Contamination of factor-VIII concentrates with metal particles. PMID- 4140428 TI - Letter: Salicylates and pregnancy. PMID- 4140429 TI - Letter: Angina pectoris with normal coronary arteries. PMID- 4140430 TI - Letter: Toxicity of chenodeoxycholic acid in rhesus monkeys. PMID- 4140431 TI - Letter: Purity criteria for chenodeoxycholic acid. PMID- 4140432 TI - Letter: Base excess and organic acidaemia. PMID- 4140433 TI - Lactic acidosis and hyperlactataemia. PMID- 4140434 TI - Letter: Familial Hodgkin's disease. PMID- 4140435 TI - Letter: Intercellular junctions between erythroblasts. PMID- 4140436 TI - Letter: Frequency of cystic-fibrosis gene. PMID- 4140437 TI - Letter: Lithium in thyrotoxicosis. PMID- 4140438 TI - Letter: Fat cells in childhood obesity. PMID- 4140439 TI - Letter: Metabolic defect in hyperornithinaemia. PMID- 4140440 TI - Letter: Menkes' kinky hair disease treated with subcutaneous copper sulphate. PMID- 4140441 TI - Letter: Herpes rugbeiorum. PMID- 4140442 TI - Letter: The consultants' contract. PMID- 4140443 TI - Letter: The "political health service". PMID- 4140444 TI - Letter: Social work and general practice. PMID- 4140445 TI - Letter: The specialty of infectious disease. PMID- 4140446 TI - Letter: Assisted entry to medical schools for health workers as mature students. PMID- 4140447 TI - Letter: A XXX-XXY marriage. PMID- 4140448 TI - Letter: Distinguishing T and B lymphocytes by light microscopy and Normarski optics. PMID- 4140449 TI - Letter: Colistin sensitivity testing. PMID- 4140450 TI - Cryosurgical treatment of recurrent head and neck malignancies-a comparative study. PMID- 4140451 TI - [The role of the lymph vessel system in diseases of the gastrointestinal tract (author's transl)]. PMID- 4140452 TI - [Recent antineoplastic agents in the treatment of solid tumors]. PMID- 4140453 TI - Mitochondrial swelling associated with exercise and method of fixation. PMID- 4140454 TI - [Bleomycin associated pneumonitis. Retrospective clinico-pathological study]. PMID- 4140455 TI - Vascular reactions to laser in vivo. PMID- 4140456 TI - The cervical lymphatic ducts of the dog: structure and function of the endothelial lining. PMID- 4140457 TI - Adrenergic innervation and vascular patterns in canine adipose tissue. PMID- 4140458 TI - Capillary pore rheology of erythrocytes. II. A method for the preparation of leucocyte-poor erythrocyte suspensions suitable for capillary pore rheometry. PMID- 4140459 TI - On pericytes, particularly their existence on lung capillaries. PMID- 4140460 TI - The place of chemotherapy in the treatment of advanced squamous carcinoma of the head and neck and in other situations. PMID- 4140461 TI - [Dextran-intolerance (author's transl)]. PMID- 4140462 TI - [Heart rhythm disorders in healthy persons]. PMID- 4140464 TI - [Hepatitis infections due to stay in tropical and subtropical developing countries, and their evaluation by an accident-insurance carrier]. PMID- 4140463 TI - [Problems of interference in artificial pacemaker's stimulation (author's transl)]. PMID- 4140465 TI - [Demonstration of collagen on semi-fine sections using two special dyes and collagen digestion]. PMID- 4140466 TI - A rapid silver protein method for nervous tissue. PMID- 4140467 TI - [Vertical distribution pattern and wind dependence of lead concentration in the air in the area of a city road crossing]. PMID- 4140468 TI - Colour vision and the 'pill'. PMID- 4140469 TI - Early interaction between animal viruses and cells. PMID- 4140470 TI - Protection of mouse spermatogonia against x-ray induced translocations. PMID- 4140471 TI - An improved rapid nuclear staining technique for permanent sections. PMID- 4140472 TI - The histochemistry of hyaluronic acid and related mucosaccharides in the cerebral and other arteries of the dog. PMID- 4140473 TI - [The contamination of roadway apples with lead]. PMID- 4140474 TI - Possible role of DNA synthesis in formation of sister chromatid exchanges. PMID- 4140475 TI - Large numbers of cells in normal mice produce antibody components of isologous erythrocytes. PMID- 4140476 TI - Histology of orofacial tumours perfused with bleomycin. PMID- 4140477 TI - [Intracystic therapy of bleomycin for craniopharyngioma--effect of bleomycin for cultured craniopharyngioma cells and intracystic concentration of bleomycin (author's transl)]. PMID- 4140478 TI - [Electron microscopic observations of two cases of monstrocellular sarcoma of the brain in vivo and in vitro (author's transl)]. PMID- 4140479 TI - Immunocytochemical localization of dopamine-beta-hydroxylase in adrenal chromaffin granules. PMID- 4140480 TI - The spinal cerebrospinal fluid absorptive pathways. PMID- 4140481 TI - Neuropathologic aspects in Menkes' Kinky hair disease (trichopoliodystrophy). Menkes' Kinky hair disease. PMID- 4140483 TI - Aspects of surgical nursing. PMID- 4140482 TI - Light microscopic staining and histochemical applications for plant meristems embedded in Spurr's medium. PMID- 4140484 TI - Disclosing wafers in an oral hygiene instruction program. PMID- 4140485 TI - [Recurrent glomus-angioma of the internal rectus muscle of the eye]. PMID- 4140486 TI - Hodgkin's disease in the elderly. PMID- 4140487 TI - Oral focal mucinosis. A clinicopathologic and histochemical study of eight cases. PMID- 4140488 TI - [Group antigens and antigenic determinants of reverse transcriptases of type C oncornaviruses]. PMID- 4140489 TI - Modifications of surface coat of aortic endothelial cells in hyperlipemic rats. PMID- 4140490 TI - The ultrastructure of elastic tissue. PMID- 4140491 TI - Corpora amylacea in parathyroids in cases of primary hyperparathyroidism. PMID- 4140492 TI - A comparative analysis of the ultrastructure, biology and pathogenicity of mycoplasmas. PMID- 4140493 TI - [Juvenile cerebral spongiosis]. PMID- 4140494 TI - Epidemiology of organochlorine insecticides in the adipose tissue of Israelis. PMID- 4140495 TI - Polychlorinated biphenyl and organochlorine pesticides residues in Canadian chicken eggs. PMID- 4140496 TI - Nature and mechanism of cellular recognition and regulation of leucocyte migration. PMID- 4140497 TI - Care of the lower limb amputee. PMID- 4140498 TI - [Effect of sucrose on the hematological and biochemical properties of blood in young fattening cattle]. PMID- 4140499 TI - [Effect of exogenously applied steroid hormones on some proteins and enzymes in rabbit blood serum]. PMID- 4140500 TI - [Growth defects in children with a large thymus]. PMID- 4140501 TI - Isolation of plasma membrane from porcine spermatozoa. PMID- 4140502 TI - Isoelectric focusing of peripheral lymphocytes. PMID- 4140503 TI - Particles with characteristics of leukoviruses in cultures of marrow cells from leukemic patients in remission and relapse. AB - An enzyme activity with the characteristics of RNA-directed DNA polymerase (reverse transcriptase) was detected in marrow from patients with leukemia in relapse and in firm hematological remission. Material having the enzyme activity, when analyzed in sucrose gradients, appeared as two distinct homogeneous bands of particles with densities of about 1.17 and 1.23 g/ml. The enzyme activity was stimulated by exogenous template poly(rC).(dG)(12-18) but not by (dT)(12-18). The enzyme activities in these bands also increased (1.7- to 24-fold) after culture, and both bands with enzyme activity were obtained from the cultured cells and from the supernatant medium. Electron microscopic studies showed that the two bands contained particles resembling leukoviruses or their cores. PMID- 4140504 TI - Similar idiotypes in antibody-forming cells and in cells synthesizing immunoglobulins without detectable antibody function. AB - The occurrence of immunoglobulins with and without antibody specificity and with and without idiotypic specificity was studied, by use of enzyme-labeled antigen and antibodies, in lymph node cells of rabbits immunized with horse-radish peroxidase and hen ovalbumin. Some cells, containing immunoglobulins without detectable antibody function, were shown to contain idiotypes similar to those found in antibody-producing cells. PMID- 4140505 TI - Sarcoma-virus-related RNA sequences in normal rat cells. AB - A rat type C virus spontaneously activated from the NRK (normal rat kidney) cell line was found to have two major size classes of viral RNA subunits sedimenting at 35 and 30 S. Virus-producing cells contained both RNA species, while normal "virus-free" rat cells contained primarily virus-specific 30S RNA species. A DNA transcript, specific for Kirsten sarcoma virus, prepared from virus activated in nonproducer BALB/c cells originally transformed by Kirsten sarcoma virus and rendered specific for the virus by absorption of sequences related to mouse helper virus hybridized only with the 30S RNA species of virus-producing rat cells and normal rat cells. These findings are consistent with the hypothesis that sarcoma-specific nucleic acid sequences in kirsten sarcoma virus emerged through a process that incorporated some portions of 30S RNA species from rat cells (either normal or virus-producing) into the Kirsten leukemia virus during passage in vivo of that virus. The virus designated M-MSV(RaLV), which originally derived from tumor induced by Moloney sarcoma virus (M-MSV) in rats, contained 35S RNA species of rat type C viruses and 30S RNA species specific for both rat and mouse viruses. It appears striking that for these two animal species, sarcoma virus-specific information resides on a 30S subunit. PMID- 4140506 TI - A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. AB - Dividing cells from persons with Bloom's syndrome, an autosomal recessive disorder of growth, exhibit increased numbers of chromatid breaks and rearrangements. A highly characteristic feature of the chromosome instability in this syndrome is the tendency for exchanges to occur between chromatids of homologous chromosomes at homologous sites. In the present experiments, a cytogenetic technique by which the sister chromatids of a metaphase chromosome are stained differentially has been used to demonstrate a striking and possibly specific, but hitherto unrecognized, increase in the frequency with which sister chromatids also exchange segments. The cells were grown in bromodeoxyuridine and stained with 33258 Hoechst and Giemsa. Whereas phytohemagglutinin-stimulated lymphocytes from normal controls had a mean of 6.9 sister chromatid exchanges per metaphase (range 1-14), those from persons with Bloom's syndrome had a mean of 89.0 (range 45-162). Normal frequencies of sister chromatid exchanges were found in cells heterozygous for the Bloom's syndrome gene, and also in cells either homozygous or heterozygous for the genes of the Louis-Bar (ataxia telangiectasia) syndrome and Fanconi's anemia, two other rare disorders characterized by chromosome instability. In a differentially stained chromatid interchange configuration discovered during the study, it was possible to determine the new distribution of both sister and non-sister-but-homologous chromatids that had resulted from numerous exchanges. By following shifts in the pattern of staining from chromatid to chromatid, visual evidence was obtained that the quadriradial configurations long recognized as characteristic of Bloom's syndrome represent exchanges between homologous chromosomes, apparently at homologous points. We postulate that the increase in the frequency of exchanges between nonsister-but homologous chromatids and those between sister chromatids in Bloom's syndrome represents aspects of one and the same disturbance. A study of this phenomenon in relation to the clinical features of Bloom's syndrome may be helpful eventually in understanding the biological significance of chromatid exchange in somatic cells. PMID- 4140507 TI - Localization of Escherichia coli ribosomal proteins S4 and S14 by electron microscopy of antibody-labeled subunits. AB - Binding sites for antibodies specific for proteins S4 and S14 of the small subunit of E. coli ribosomes have been mapped on the surface of the subunit by electron microscopy. Antibody binding to reconstituted subunits was shown to depend specifically on the presence of E. coli S4 and S14. Anti-S14 IgG was found to bind to a limited region of the ribosome surface. In contrast anti-S4 IgG was found to bind to three separated regions of the ribosome surface, suggesting S4 has an elongated conformation in situ. PMID- 4140508 TI - Type C viral antigens in man. I. Antigens related to endogenous primate virus in human tumors. AB - Partially purified extracts from 33 human tumors of several histologic types were used as competing antigens in a radioimmunoassay for the p30 protein of an endogenous primate type C virus (M7). Antigens immunologically related to the p30 protein of the M7 virus were detected in two tumors. Like viral p30 antigens previously identified in tissues of several other primates, the antigens found in human tumors crossreact with the p30 protein of the feline RD-114 virus but are unrelated by similar immunologic criteria to the p30 proteins of several other mammalian type C viruses. Gel filtration shows that most of the antigenic activity co-chromatographs with authentic p30 protein. These results, along with those showing nucleic acid sequences related to those of an endogenous primate type C virus in the DNA of human cells, make it clear that humans, like other primates, have type C viral sequences in their genome and can, in some circumstances, express at least one type C viral protein. PMID- 4140509 TI - The identification of the eukaryotic ribosomal proteins homologous with Escherichia coli proteins L7 and L12. AB - Antibodies were raised against eukaryotic (rat liver) and prokaryotic (E. coli) ribosomal particles and ribosomal proteins. The antisera were characterized and used to determine the identity of the eukaryotic proteins homologous to E. coli L7 and L12. The large subunit of rat liver ribosomes contains two acidic proteins, L40 and L41; they migrate during two-dimensional polyacrylamide gel electrophoresis in a way that mimics the behavior of L7 and L12. Rat liver L40 and L41 were found to be immunologically related to E. coli L7/L12, hence the proteins are likely to share some structural homology. PMID- 4140510 TI - Actin is the naturally occurring inhibitor of deoxyribonuclease I. AB - Various tissues and cells in culture contain a specific inhibitor of DNase I (EC 3.1.4.5). In this paper evidence is presented that this inhibitor is actin, one of the major structural proteins of muscle and nonmuscle cells. (a) The inhibitor is a major cellular component constituting 5-10% of the soluble protein. (b) It migrates with actin on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, having a characteristic molecular weight of 42,000. (c) It has an amino-acid composition closely similar to that of actin. (d) The peptide maps of the two proteins are nearly identical. (e) Skeletal muscle actin inhibits the enzymatic activity of DNase I. (f) DNase I-agarose affinity chromatography quantitatively retains purified skeletal muscle actin, and actin, specifically, from high-speed supernatants of whole cell extracts. (g) An antibody to purified inhibitor protein from calf thymus, used in indirect immunofluorescence on cells grown in culture, stains a two-dimensional network of fibers similar to that seen with an actin-specific antibody.The observation that actin can be isolated by DNase agarose affinity chromatography provides a useful tool for the biochemical study of actin under different physiological conditions. PMID- 4140511 TI - The regulation of protein synthesis in mammalian cells VI. Soluble and polyribosome associated components in controlling in vitro polypeptide initiation in HeLa cells. AB - The in vitro initiation of polypeptides on endogenous polyribosomes has been studied in extracts from HeLa cells. Regulation of the rate of initiation of polypeptides can be examined. In these experiments an assay using [(35)S]fMet tRNA(f) (Met) has been developed, and the system further characterized. The system has been separated into a fraction containing polyribosomes with subunits and a fraction containing soluble components. The regulation of initiation has at least two distinct components. There is one factor in the soluble fraction which develops a stimulated response after protein synthesis has been inhibited in intact cells. This stimulation does not require new RNA synthesis during the period of cell "stress."A second component is associated with ribosomes. This factor is necessary for the initiation of polypeptides on endogenous polyribosomes. It disappears gradually when cells are exposed to actinomycin. The disappearance is first manifested by an inability of polyribosomes to respond to stimulated supernatants. This unstable component, which decays in the presence of actinomycin, has no apparent counterpart in systems that measure initiation on exogenous mRNA. PMID- 4140512 TI - Alterations of membrane glycopeptides in human colonic adenocarcinoma. AB - Membrane glycopeptides were examined in human colonic adenocarcinoma and normal colonic mucosa. The carbohydrates of membrane glycopeptides were found to be markedly reduced in tumor tissue and the relative proportions of the various sugars were altered. Although all of the sugars were lower in tumor tissue when compared to the adjacent normal mucosa, galactosamine, fucose, and sialic acid were more significantly reduced. Examination of the blood group activity and lectin-binding properties of membrane glycopeptides revealed that specific carbohydrate structures had changed in the tumor tissue. Most striking of these changes was the disappearance of glycoprotein-associated blood group A activity. Assay of the enzyme responsible for synthesis of the blood group A determinant showed that this glycosyltransferase activity was greatly diminished in tumor tissue. A galactosyltransferase and a fucosyltransferase were also significantly lower in the tumor tissue whereas the levels of another galactosyltransferase and a sialyltransferase were unaltered. Glycosidase activities in the normal and tumor tissues were similar. The results show that an alteration in glycoprotein biosynthesis occurred during tumorigenesis that resulted in a modified membrane glycoprotein composition and that these changes are probably a reflection of reduced levels of the enzymes responsible for glycoprotein synthesis. PMID- 4140513 TI - Reverse transcriptase: correlation of zinc content with activity. AB - Evidence is presented that DNA polymerase of avian myeloblastosis virus has an obligatory zinc requirement for activity. Previous studies indicate that the purified polymerase contains zinc in a stoichiometry of about 1 g-atom/mole. We now find that the enzyme-bound zinc is exchangeable with radioactive (65)Zn; after isoelectric focusing, the radioactive (65)Zn is coincident with polymerase activity. Dialysis of the (65)Zn-labeled polymerase against the chelator, 1,10 phenanthroline, results in a progressive loss of radioactive (65)Zn and polymerase activity. Thereupon, incubation of the inactivated enzyme with Zn(2+) fully restores activity. Thus, the DNA polymerase present in an oncogenic RNA virus, like animal DNA polymerases, can be rigorously classified as a zinc metalloenzyme. DNA polymerase of avian myeloblastosis virus is inactivated by 1,10-phenanthroline at a much faster rate than the bacterial and animal DNA polymerases that have been tested. It may, therefore, be possible to inactivate selectively DNA polymerases from animal tumor viruses by brief exposure to appropriate metal chelators. PMID- 4140514 TI - Studies on the reverse transcriptase of RNA tumor viruses. Structural relatedness of two subunits of avian RNA tumor viruses. AB - The structural relationship of the small (alpha) and large (beta) subunits of reverse transcriptase isolated from two avian RNA tumor viruses has been examined by tryptic peptide analysis. Comparison of the tryptic hydrolysates of the isolated subunits by two-dimensional separation on thin-layer cellulose plates indicates that (i) the alpha subunit of reverse transcriptase of avian myeloblastosis virus is structurally related to the beta subunit; (ii) the alpha and beta subunits of the enzyme of Rous sarcoma virus also appear to be related; and (iii) there appears to be an extensive amino-acid sequence homology between reverse transcriptases of avian myeloblastosis virus and Rous sarcoma virus. Evidence is also presented that both alpha and beta subunits can be identified in purified avian myeloblastosis virions. PMID- 4140515 TI - The presence of I-region-associated antigens on B cells in molecules distinct from immunoglobulin and H-2K and H-2D. AB - The distribution of I-region-associated antigenic specificities in murine lymphoid cells was studied by immunofluorescence. The antigens were mostly represented in B cells and in macrophages. The complexes of I-anti-I-region associated antigens were found to be distributed throughout the lymphocyte surface both at 4 degrees and 37 degrees . In about two-thirds of the lymphocytes the complexes redistributed into caps after incubation with a second ligand (an anti-mouse immunoglobulin). The I-region specificities were in molecules distinct from immunoglobulin or from the molecules coded by the H-2K and H-2D regions. PMID- 4140516 TI - Nonhistone proteins control gene expression in reconstituted chromatin. AB - Chromatin was reconstituted from the purified DNA and histones of chicken erythrocytes and the nonhistone proteins of either chicken reticulocytes or chicken liver. Reconstituted chromatins, native chicken reticulocyte chromatin, and free DNA were transcribed with Escherichia coli RNA polymerase and the concentrations of globin-specific sequences in the RNA products were measured by hybridization with [(3)H]DNA complementary to chicken globin messenger RNA. Reticulocyte, but not liver, nonhistone proteins were shown to activate the globin genes in reconstituted erythrocyte chromatin. The transcripts of native and reconstituted chromatins were indistinguishable in respect of both the total yield of the RNA and the fractional yield of globin-specific sequences. PMID- 4140517 TI - Regulation of immune response by autogenous antibody against receptor. AB - BALB/c mice repeatedly immunized with Pneumococcus R36A vaccine produce antibodies to phosphorylcholine having the TEPC-15 myeloma idiotype (murine IgA myeloma protein that binds phosphorylcholine). The plaque-forming cell response to phosphorylcholine shows a decrease with repeated immunizations. In contrast, spleen cells from multiply immunized mice responded better in vitro than spleen cells from nonimmunized mice. The serum of animals immunized four or five times agglutinates TEPC-15-coated sheep erythrocytes. Inhibition of hemagglutination shows that the agglutinating activity is directed against the TEPC-15 idiotype. Sera from these mice, when added to cultures of normal spleen cells, specifically suppress the response to phosphorylcholine. The suppressive activity in the serum can be removed by solid absorption with TEPC-15. Evidently, repeated immunization with antigen induces two kinds of antibody responses: one directed against antigen and the other directed against the antibody to the antigen. It is proposed that this "auto" antibody against receptor is involved in the regulation of the immune response. PMID- 4140518 TI - Solitary plasmacytoma of the clavicle. PMID- 4140519 TI - Measles vaccines. PMID- 4140520 TI - Mixed lymphocyte culture determinants, measles infection and multiple sclerosis. PMID- 4140521 TI - Platelet aggregation and release triggered by antibody to platelet factor 4 (PF4). PMID- 4140522 TI - Anaphylactoid edema induced in rats by nickel and cobalt salts. PMID- 4140523 TI - Induction of guinea pig leukemia-like virus from cultured guinea pigs cells. PMID- 4140524 TI - Determination of uterine blood volume and correlation with ovarian function. PMID- 4140525 TI - The effects of thyroid state on rat liver glucose-6-phosphatase activity and glycogen content. PMID- 4140526 TI - Comparative effects of pancuronium and d-tubocurarine on blood histamine and sympathetic activity. PMID- 4140527 TI - Microtubules in prolactin cells of the rat anterior pituitary gland. PMID- 4140528 TI - Effect of con A on tolerance to BGG in NZB-W mice. PMID- 4140529 TI - Suppression of prolactin secretion by acute administration of delta9-THC in rats. PMID- 4140530 TI - Chromosome changes revealed by the Q-band staining method during cell senescence of WI-38. PMID- 4140531 TI - Drug displacement from protein-binding and redistributional interactions. PMID- 4140532 TI - Metabolic side-effects of allopurinol. PMID- 4140533 TI - [Preparation of salicylic acid-albumin and salicylic acid-globulin conjugates]. PMID- 4140534 TI - Some electron microscopic studies on intact nuclear 'ghosts' and nuclear membrane fragments. PMID- 4140535 TI - Crystalline glycoprotein cell walls of algae: their stucture, composition and assembly. PMID- 4140537 TI - Experimental study of the regeneration of sympathetic nerve fibers after nerve homografting. PMID- 4140539 TI - Mechanisms of immunological enhancement. PMID- 4140541 TI - Chemical pollutants with special reference to sources of pollution. PMID- 4140540 TI - Alpha-fetoprotein: expression in human disease and in rat experimental models. PMID- 4140542 TI - [The antigenic determinants of lysozyme (author's transl)]. PMID- 4140543 TI - [Biochemistry of histocompatibility alloantigens (author's transl)]. PMID- 4140544 TI - [Flagellar antigen of Salmonella (author's transl) ]. PMID- 4140545 TI - [Experimental allergic encephalomyelitis antigen (author's transl)]. PMID- 4140546 TI - [Structure and function of immunoglobulin G (author's transl)]. PMID- 4140547 TI - [Antigenicity of immunoglobulin (author's transl)]. PMID- 4140548 TI - [Cellular mechanisms in induction of antibody response (author's transl)]. PMID- 4140549 TI - [Myelin proteins and demyelinating disease (author's transl)]. PMID- 4140550 TI - [Trochanteroplasty. Salvage operation in mutilations of the femoral head and neck in children. Indications, technic and results, apropos of 10 cases]. PMID- 4140552 TI - [Iodine and thyroxine metabolism in progressive muscular dystrophy]. PMID- 4140551 TI - [Immunological rings in the cornea after the systematic administration of antivariolic gamma globulin (VIG) in the treatment of ocular vaccinia]. PMID- 4140553 TI - [Effect of l-dopa on the thyroid function and the plasma lipids (author's transl)]. PMID- 4140555 TI - Classification of acute leukaemias using Romanowsky, sudan black and periodic acid Schiff stains. PMID- 4140554 TI - Tumours of liver, biliary system and pancreas. PMID- 4140556 TI - Introduction to nomenclature and classification of acute leukemias. PMID- 4140557 TI - Practical value of cytochemical studies for the classification of acute leukemias. PMID- 4140558 TI - Indications and limits of cytochemistry in acute leukemia. PMID- 4140559 TI - Reaginic antibody in experimental allergic encephalomyelitis. I. Characterization of heat-labile skin-fixing antibody. PMID- 4140560 TI - Reaginic antibody in experimental allergic encephalomyelitis. II. Histamine and serotonin blockade. PMID- 4140561 TI - Effects of chronic ingestion of some lower aliphatic alcohols in rats. PMID- 4140562 TI - Localization of narcotic analgesics in synaptic membranes of rat brain. PMID- 4140563 TI - [The determination of DNA and its contribution in the nucleus in experimental cancer of the large intestine of the rat and its precursors (author's transl)]. PMID- 4140564 TI - [Vitalmicroscopic studies of the perivascular connective tissue using interference technique (author's transl)]. PMID- 4140565 TI - [Rhabdomyosarcoma]. PMID- 4140566 TI - [Diagnosis of drug allergies]. PMID- 4140567 TI - [Histamine metabolism in hemorrhagic-hypotensive shock]. PMID- 4140568 TI - Histochemical study of the formation of dental plaque in artificial fissures. PMID- 4140569 TI - A national therapy project for drug resistant pulmonary tuberculosis. PMID- 4140571 TI - Interdisciplinary management of developmental disabilities cases. PMID- 4140570 TI - [Splenic lipidosis with or without ceroids in idiopathic thrombopenic purpura]. PMID- 4140572 TI - Pachytene analysis of acrocentric human chromosomes. PMID- 4140573 TI - [Mechanisms of the effect of corticosteroid therapy on arterial pressure in chronic glomerulonephritis]. PMID- 4140574 TI - [Autohemotransfusion in surgical treatment of prostatic adenoma]. PMID- 4140575 TI - [Clinico-morphological characteristics of prostatic adenoma in different variants of its course]. PMID- 4140576 TI - Radioimmunoassay for gamma-a fetal protein in serum of patients with cancer and nonmalignant diseases. PMID- 4140577 TI - Oxygen consumption by acrylamide polymerization for rapid screening of chemotherapeutic agents. PMID- 4140578 TI - Corneal nerves. PMID- 4140579 TI - [Immunological aspects of the borderline forms of connective tissue diseases]. PMID- 4140580 TI - [Borderline forms between rheumatoid arthritis and systemic lupus erythematosus]. PMID- 4140582 TI - [Virus as a cause of leukemia and blood cell disease in man]. PMID- 4140581 TI - [Histamine-liberation effect of hypotensive compounds present in various human serum albumins. Relation with blood group substances]. PMID- 4140583 TI - [Reoperation for lesions of the left ventricular outflow tract (author's transl)]. PMID- 4140584 TI - [On Brook's infundibulectomy and subsequent total correction of the tetralogy of Fallot (author's transl)]. PMID- 4140585 TI - [Histochemical studies of the extension of necrosis following temporary regional myocardial ischemis in pigs (author's transl)]. PMID- 4140586 TI - [Nuclear medical studies for the determination of right-to-left cardiac shunting in infants with congenital cyanotic heart disease by perfusion lung scans and total-body count (author's transl)]. PMID- 4140587 TI - Lack of association between carcinoma of the breast and HL-A specificities. PMID- 4140588 TI - Inhibition of the mixed lymphocyte reaction by sera from multipara. PMID- 4140589 TI - Subacute thyroiditis: observations on 98 cases for the last 14 years. PMID- 4140590 TI - Influence of phosphororganic radioprotective drugs on postirradiation changes of reactivity to barium chloride in guinea pig intestine. PMID- 4140591 TI - Pertinent features of M locus determinants including revised nomenclature and strain distribution. PMID- 4140592 TI - Rabbit anti-human thymocyte globulin (RAHTG): in vitro and in vivo testing. PMID- 4140593 TI - Evaluation of the efficiency of leukocyte transfers by Y-chromatin studies. PMID- 4140594 TI - Typing for the MLC determinants and its possible impact on Europdonor. PMID- 4140595 TI - Genetics of the human histocompatibility system HL-1. PMID- 4140596 TI - Cross-reactive antigens, cancer, and transplantation. PMID- 4140597 TI - Immunological enhancement of renal allografts. PMID- 4140598 TI - [Technic of obtaining oocytes from rats and mice and staining the constituent heterochromatin in meiotic chromosomes]. PMID- 4140599 TI - [Detection of cationic proteins in the cytoplasm of leukocytes with the use of bromphenol blue]. PMID- 4140600 TI - [Sorption properties of cells of regenerating liver]. PMID- 4140601 TI - [Treatment of pulmonary tuberculosis in developing countries]. PMID- 4140602 TI - Nursing in Padang, Indonesia. PMID- 4140603 TI - Human prostatic reverse transcriptase and RNA-virus. PMID- 4140605 TI - Intracisternal hyalin in hepatocytes of human liver biopsies. PMID- 4140604 TI - Isolation of glomeruli and tubular fragments from rabbit kidney. PMID- 4140606 TI - Distinguishing normal human blood lymphocytes from lymphocytes in dengue and typhoid fever. PMID- 4140607 TI - Polypeptide hormone production by "carcinoid" apudomas and their relevant cytochemistry. PMID- 4140608 TI - [Results of treating trophoblastic disease (based on data from the N. N. Petrov Research Institute of Oncology of the Ministry of Public Health of the USSR)]. PMID- 4140610 TI - [Some ultrastructural characteristics of the cancer cell compared with the embryonic cell]. PMID- 4140609 TI - [Production of oncornaviruses by cell cultures]. PMID- 4140611 TI - [Changes in the connective tissue of the mammary glands in tumor induction in rats]. PMID- 4140612 TI - [Chemotherapy of trophoblastic disease]. PMID- 4140613 TI - [Histochemical data on human skin melanoma in relation to treatment]. PMID- 4140614 TI - [Characteristics of a human ovarian cancer cell line]. PMID- 4140615 TI - [Detection of a specific antigen in the bone marrow of animals administered antiviral vaccines]. PMID- 4140616 TI - [Cytological methods of detecting the contamination of primary kidney tissue cultutes from green monkeys by extraneous viruses]. PMID- 4140617 TI - [Study of the interaction of the replicative form of the RNA of the encephalomyocarditis virus with actinomycin]. PMID- 4140618 TI - [Blood platelets and their role in hemostasis]. PMID- 4140619 TI - [Hormonal treatment of prostatic hypertrophy with special reference to the usefulness of gestagens]. PMID- 4140620 TI - [Blood and plasma viscosity in liver cirrhosis (author's transl)]. PMID- 4140621 TI - [Different density of antigenic determinants on alveolar and peritoneal macrophages (author's transl)]. PMID- 4140622 TI - [Further immunological phenomena in ulcerative colitis (author's transl)]. PMID- 4140624 TI - [School and occupational aids for patients with vision disorders or blindness]. PMID- 4140623 TI - [Advances in the surgical treatment of skin tumors]. PMID- 4140625 TI - [Catamnestic studies on the shoulder-hand syndrome]. PMID- 4140626 TI - [Department developmental problems--report on a model]. PMID- 4140627 TI - [Protein binding of biologically active substances and the therapeutic significance of its modification]. PMID- 4140628 TI - [Significance and necessity of metaphylactic studies in bladder cancer]. PMID- 4140629 TI - [Mastocytosis and urticarial changes in the gastrointestinal tract: endoscopic findings in 3 cases]. PMID- 4140630 TI - [Endoscopic intravital staining in the stomach]. PMID- 4140631 TI - Electrophoretic examination of cerebrospinal fluid proteins in children with acute lymphocytic leukemia. II. Communication. PMID- 4140632 TI - Changes of the protein composition of the cerebrospinal fluid in childhood acute leukemia. PMID- 4140633 TI - [The quantitative immunological determination of serum proteins (author's transl)]. PMID- 4140634 TI - [Studies on the direct radioimmunological determination of triiodothyronine in serum (author's transl)]. PMID- 4140635 TI - [Comparative studies on four thrombocyte counting methods: counting in the smear preparation after Fonio, chamber counting in the phase contrast microscope, counting with the Coulter Thrombocounter, and the Technicon Auto-Counter]. PMID- 4140636 TI - Studies on the application of 125I labelled testosterone in protein binding methods. PMID- 4140637 TI - Routine procedure for the separation of the isoenzymes of alkaline phosphatase. PMID- 4140638 TI - Experimental ependymomas: in vivo and in vitro morphology. PMID- 4140639 TI - Histamine and serotonin in the gastric erosions of rats dead from exposure to cold: a histochemical and quantitative study. PMID- 4140640 TI - Studies on the antigenic determinant group of the type-specific antigen of Leptospira canicola. PMID- 4140641 TI - Review of the global epidemiological situation of plague since the last Congress of Tropical Medicine and Malaria in 1968. PMID- 4140642 TI - [Structural organization of the descending pathways that participate in the activation of the flight of the Asiatic locust, Locusta migratoria]. PMID- 4140643 TI - [Effect of gamma-globulin administration on the immunoglobulin content in the blood serum of healthy children]. PMID- 4140644 TI - Acid phosphatase from human prostate. Chemical modification and activity of the enzyme. PMID- 4140645 TI - Open heart surgery in the first year of life. PMID- 4140646 TI - Fluorometric characterization of six classes of human leukocytes. PMID- 4140647 TI - Membrane properties of lymphatic cells in fine needle biopsies of lymphomas. I. Cap formation after exposure to fluorescein conjugated concanavalin A. PMID- 4140648 TI - Cytological effects of thio-TEPA on ascites tumors in mice. PMID- 4140649 TI - Quality evaluation of cytology laboratories in New York State: expanded program, 1971-73. PMID- 4140650 TI - Some cytochemical properties of isolated human endosalpingeal cells. PMID- 4140651 TI - A new technique for colonic cytology. PMID- 4140652 TI - Cytologic diagnosis in primary carcinoma of Fallopian tube. Case report and review. PMID- 4140654 TI - An improved method for the preparation of epidermal sheets. PMID- 4140653 TI - Studies on guinea pig skin cell cultures. IV. Collagen synthesis. PMID- 4140655 TI - Ultrastructure of necrobiosis lipoidica diabeticorum. PMID- 4140656 TI - Participation of singlet state excites oxygen in photohemolysis induced by kynurenic acid. PMID- 4140657 TI - Immunological tolerance and dermal eosinophilia induced in dinitrochlorobenzene sensitized guinea pigs. PMID- 4140658 TI - HL-A-antigens and psoriatic arthritis. PMID- 4140659 TI - Correlative study of rubella antibody titre, basement zone antibody titre, and IgG content of sera of patients with bullous pemphigoid. PMID- 4140660 TI - Precipitating antibodies to sulfathiazole in serum of patients with suspected allergy to sulfonamides. PMID- 4140661 TI - Studies on tryptophan catabolism in acrodermatitis enteropathica. PMID- 4140662 TI - Hematological changes in psoriasis. Secondary anemia, XVIII. PMID- 4140663 TI - Occupational and non-occupational scrotal cancer in Sweden, 1958-1970. PMID- 4140664 TI - Hyperkeratosis lenticularis perstans (Flegel). PMID- 4140665 TI - On the occurrence of genital herpes simplex virus infection. Clinical and virological findings and relation to gonorrhoea. PMID- 4140666 TI - Effects of long term treatment with tetracycline. PMID- 4140667 TI - Treatment of light sensitivity with carotenoids. Serum concentrations and light protection. PMID- 4140668 TI - Letter: Etiology of erythropoietic protoporphyria, and protection of photosensitive subjects. PMID- 4140669 TI - Changes in the level of immunoglobulins in the Danzig quintuplets in their first year of life. PMID- 4140670 TI - Observation of the cells of basophilic series by Astra blue staining. PMID- 4140671 TI - Staining of cholesterol with the fluorescent antibiotic "filipin". PMID- 4140672 TI - On the structure and histochemistry of the cuticle of austroperipatus Peripatoides novae zealandiae. PMID- 4140673 TI - Urea and pyridine in Feulgen staining of Bryophyllum. PMID- 4140674 TI - Ruthenium red and lanthanum nitrate a possible tracer and negative stain for scrapie "particles"? PMID- 4140675 TI - The growth of the cranial base in the Wistar albino rat studied by vital staining with alizarin red S. PMID- 4140676 TI - Studies on the factors inducing metastasis of breast cancer to lymph node. I. Lymph flow in the thoracic wall. PMID- 4140677 TI - Measles virus antibodies in multiple sclerosis. PMID- 4140678 TI - Taxonomic criteria for Mycobacteria and nocardiae. PMID- 4140679 TI - Human experiences related to adverse drug reactions to the fetus or neonate from some maternally administered drugs. PMID- 4140680 TI - Transmitter release and recycling of synaptic vesicle membrane at the neuromuscular junction. PMID- 4140681 TI - Cytochemical studies of secretory and other granules associated with the endoplasmic reticulum in rat thyroid epithelial cells. PMID- 4140682 TI - Stereological study of pancreatic exocrine cells. PMID- 4140683 TI - Activation of mammalian leukemia viruses. PMID- 4140684 TI - Structural components of rna tumor viruses. PMID- 4140685 TI - [Telecobalt in the treatment of bladder cancer. Results after 5 years and postradiotherapy sequelae]. PMID- 4140686 TI - Localization of granules stained artifactually with the Fink-Heimer technique in certain brain stem nuclei of the pigeon. PMID- 4140688 TI - Dominant piebald trait in a retarded child with a reciprocal translocation and small intercalary deletion. PMID- 4140687 TI - Viral potentiation of chemical toxins in the experimental syndrome of hypoglycemia, encephalopathy, and visceral fatty degeneration. PMID- 4140689 TI - A familial X-22 translocation with an extra X chromosome. PMID- 4140690 TI - Pericentric inversions of human chromosomes 9 and 10. PMID- 4140691 TI - Declining testicular function with age. Hormonal and clinical correlates. PMID- 4140692 TI - Staining of glutaraldehyde fixed, glycol methacrylate embedded hamster lungs. PMID- 4140693 TI - Timely topics in clinical chemistry: in vitro thyroid testing. PMID- 4140694 TI - Evaluation of a new automated tissue stainer. PMID- 4140695 TI - Effect of adrenergic blockade and specific antithyroid therapy on electrocardiographic changes in hyperthyroidism. PMID- 4140696 TI - A light and electron microscopic study of anterior subcapsular cataracts. PMID- 4140697 TI - Clinical, pathologic, and therapeutic aspects of carcinoma of the pancreas. PMID- 4140698 TI - [Types of vaginal smears in late pregnancy and their prognostic value]. PMID- 4140699 TI - Junctions between the cells of the trabecular meshwork. PMID- 4140700 TI - Some morphological features of the myoneural junctions in certain normal muscles of the rat. PMID- 4140702 TI - Bronchoprovocative tests (BPT) in clinical and experimental allergy. PMID- 4140701 TI - The effect of proteolytic enzymes and hyaluronidase on the intracellular beta- and gamma-metachromatic granules and the matrix of rat epiphyseal cartilage. PMID- 4140703 TI - [L.A.T.S. activity during hyperthyroidism. Apropos of 143 cases of Basedow's disease]. PMID- 4140704 TI - [Immunological phenomenon in experimental toxoplasmosis. II. Qualitative and quantitative kinetic development of serum constituents in CBA mice]. PMID- 4140705 TI - Evaluation of the outcome of pregnancy in threatened abortion by biochemical methods. PMID- 4140706 TI - On the origin of RNA tumor viruses. PMID- 4140707 TI - The relationship between genes and polytene chromosome bands. PMID- 4140708 TI - Fluorescent antibody study of the gram-positive anaerobic cocci. AB - Fluorescent antibody conjugates were prepared from five species of anaerobic cocci commonly isolated from human infections. When tested with homologous and heterologous cells these conjugates were found to be highly specific. There was no evidence of a common genus antigen. Peptococcus magnus conjugates detected a species-specific antigen; cross-reactions with Peptostreptococcus anaerobius were readily eliminated by absorption. The conjugates from Peptococcus asaccharolyticus, Peptococcus prevotii, Peptostreptococcus, anaerobius, and Peptostreptococcus intermedius displayed a high degree of strain specificity. Occasional cross-reactions were detected with homologous strains, suggesting the presence of common antigens, but no attempt was made to determine the number of different serotypes in these species. PMID- 4140709 TI - Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5 azacytidine. Studies on methylation of 45S and 32S RNA. PMID- 4140710 TI - Renin and hypertension in childhood. PMID- 4140711 TI - Plasma proteins in meconium from normal infants and from babies with cystic fibrosis. PMID- 4140712 TI - Proceedings: Antigen catabolism in New Zealand and other strains of mice. PMID- 4140713 TI - Impaired gastric secretion in rats treated with 5-azacytidine. PMID- 4140714 TI - [Amino acid metabolism and control of cell volume]. PMID- 4140715 TI - The cytopathology and development of a human polyoma virus (B.K.). PMID- 4140716 TI - Morphology of SMON virus. PMID- 4140717 TI - [Methods of studying the chromosomes in gametogenesis and embryogenesis in mammals]. PMID- 4140718 TI - Muscle in Lafora disease. PMID- 4140719 TI - Immunoglobulins of human dental plaque. PMID- 4140720 TI - [Structure and function of the stimulated adrenal cortex. 1. Early changes of the nuclear volume in the adrenal cortex of the rat after ACTH]. PMID- 4140721 TI - Studies on the biosynthesis of tetrahymanol in Tetrahymena pyriformis. The mechanism of inhibition by cholesterol. AB - Tetrahymanol biosynthesis by the protozoan Tetrahymena pyriformis was progressively inhibited by the inclusion of cholesterol in the growth medium. Studies with labelled precursors of tetrahymanol have established that there are two major sites of inhibition in whole cells. The inhibition at the first site, between acetate and mevalonate, occurred rapidly after addition of cholesterol. The activity of 3-hydroxy-3-methylglutaryl-CoA reductase (EC 1.1.1.34), a predominantly cytosolic enzyme in this organism, was not inhibited in cholesterol grown cells nor by addition of cholesterol directly to the assay medium. The second major site of inhibition in whole cells is between mevalonate and squalene and this is accompanied by inhibition of the enzyme that converts farnesyl pyrophosphate into squalene (squalene synthetase). Squalene cyclase is partially inhibited. The conversion of mevalonate into tetrahymanol in vitro was not inhibited by the addition of cholesterol to the assay medium. Tetrahymanol added to the culture medium is taken up by the cells but does not inhibit endogenous biosynthesis. It is suggested that cholesterol inhibits the later stages of tetrahymanol biosynthesis by causing a change in membrane structure and function which alters the activity of membrane-bound enzymes. PMID- 4140722 TI - Uroporphyrin formation induced by chlorinated hydrocarbons (lindane, polychlorinated biphenyls, tetrachlorodibenzo-p-dioxin). Requirements for endogenous iron, protein synthesis and drug-metabolizing activity. PMID- 4140723 TI - Damage of rat liver deoxyribonucleic acid by bleomycin. PMID- 4140724 TI - [Acute effects of sulfur dioxide on the blood circulation of animals as well as on the contractility of isolated blood vessels]. PMID- 4140725 TI - [Cytophotometric characterization of bursal lymphocytes in hatching chickens]. PMID- 4140726 TI - Electron microscopic study of 'Rushton' hyaline bodies in cyst linings. PMID- 4140727 TI - Perineal retropubic prostatectomy. PMID- 4140728 TI - Macrophage electrophoretic mobility (MEM) test in cancer: a critical evaluation. PMID- 4140729 TI - Abnormal cells in ther peripheral blood of patients with Hodgkin's disease. I Observation with light microscopy. PMID- 4140730 TI - Abnormal cells in the peripheral blood of patients with Hodgkin's disease. II. Ultrastructural studies. PMID- 4140731 TI - Organization and use of multi-disciplinary teaching laboratories at the new medical school, Nottingham. PMID- 4140732 TI - [Letter: Electrogenic active ion transport in muscle fibers in the presence of oxidative phosphorylation uncouplers]. PMID- 4140733 TI - [Effect of anions on the anomalous behavior of actin solutions stained with acridine orange]. PMID- 4140734 TI - [Letter: Role of cations in the anomalous behavior of actin stained with acridine orange]. PMID- 4140735 TI - [Change in certain properties of DNA under the influence of oxytetracycline]. PMID- 4140736 TI - [Preparation and properties of a crystalline antithyroid phytoprecipitin from the seeds of the pea, Pisum sativum L]. PMID- 4140737 TI - [Effect of gramicidin S on the respiratory parameters of rat liver mitochondria]. PMID- 4140739 TI - [Cellular reaction of the hepatic stroma during various rhythms of pathogenic influence]. PMID- 4140738 TI - Radioimmunoassay of alpha-fetoprotein. V. Influence of age on the physiological serum alpha-fetoprotein level in man and in rat. PMID- 4140740 TI - [Reaction of the thyroid gland to changes in the concentration of plasmin in the blood]. PMID- 4140741 TI - Immunodiffusion analysis of mouse leukemia antigens. PMID- 4140742 TI - Detection of common antigenic properties of the pollen of various species of ragweed by passive sensitization of strips of nomkey ileum. PMID- 4140744 TI - Editorial: Health progress in the Americas. PMID- 4140743 TI - Selective reaction of effector lymphocytes of transplantation immunity to private specificities of the H-2K and H-2D loci. PMID- 4140745 TI - Partial thyroidectomy for thyrotoxicosis. PMID- 4140746 TI - A trial of 1-(2-chlorethyl)-3-(4-methyl-cyclohexyl)-1-nitrosourea in the treatment of patients with advanced gastro-intestinal cancer. PMID- 4140747 TI - Editorial: Drug targets in cancer chemotherapy. PMID- 4140748 TI - Transport and changes of activity of choline acetyltransferase in the peripheral stump of an interrupted nerve. PMID- 4140749 TI - Afferents to the septal area of the rat studied with the method of retrograde axonal transport of horseradish peroxidase. PMID- 4140750 TI - Uptake and transport of horseradish peroxidase by cut end of the vagus nerve. PMID- 4140751 TI - An improved silver impregnation method for tracing degenerating nerve fibers and their terminals in frozen sections. PMID- 4140752 TI - Diurnal variations of serum cortisol and PBI in the thoroughbred horse and effect of physical effort on plasma cortisol concentration. PMID- 4140753 TI - New chemotherapeutic agents--bleomycin and adriamycin. PMID- 4140754 TI - Lupus pericarditis. AB - This report documents a case of systemic lupus erythematosus in which the major presenting feature was pericarditis and in which the diagnosis was made after pericardiocentesis by the demonstration of typical LE cells in pericardial fluid stained with Wright's stain. Review of the literature indicates that pericarditis in lupus is more common than is generally suspected, and when it is the initial manifestation it is often misdiagnosed as "benign viral pericarditis".Screening for collagen disease should be a part of the work-up of any patient presenting with pericarditis, especially a woman. Occasionally lupus may be present even when the serologic tests have given negative results. Under such circumstances, or when the patient manifests an atypical or prolonged course, a diagnostic pericardiocentesis is in order, provided an effusion can be confirmed on scan. A search for LE cells should be included in the analysis of the aspirated fluid. PMID- 4140755 TI - A cytochemical and autoradiographic study of oocyte nucleoli in Limnaea stagnalis L. PMID- 4140756 TI - An investigation of ageing in human costal cartilage. PMID- 4140758 TI - Correlation between microtubular number and transport activity of hypothalamo neurohypophyseal secretory neurons. PMID- 4140759 TI - Vital staining of specific monoamine-containing cells in the leech nervous system. PMID- 4140757 TI - On the structure of the human archicortex. I. The cornu ammonis. A Golgi and pigmentarchitectonic study. PMID- 4140760 TI - The ultrastructural localization of fibrinogen at the erythrocyte surface and in the capillary endothelium. PMID- 4140761 TI - A quantitative identification of three muscle fiber types in the body muscles of Lampetra fluviatilis, and their relation to blood capillaries. PMID- 4140762 TI - Ultrastructure of the neurosecretory system of the Colorado potato beetle, Leptinotarsa decemlineata (Say). I. Characterization of the protocerebral neurosecretory cells. PMID- 4140763 TI - Ultrastructure of the neurosecretory system of the Colorado potato beetle, Leptinotarsa decemlineata (Say). II. Pathways of axonal secretion transport and innervation of neurosecretory cells. PMID- 4140764 TI - Distribution and properties of gastrin cells in the gastrointestinal tract of chicken. PMID- 4140765 TI - Studies on central projections of the pineal nerve tract in rainbow trout, Salmo gairdneri Richardson, using cobalt chloride iontophoresis. PMID- 4140766 TI - Synthesis and intracellular transport of proteins in the exocrine pancreas of the frog (Rana esculenta). I. An ultrastructural and autoradiographic study. PMID- 4140767 TI - Neurosecretion in the external and internal zone of the median eminence of the cat and dog. PMID- 4140768 TI - Nematosomes or nucleolus-like bodies in hypothalamic neurons, the subfornical organ and adenohypophysial cells of the rat. PMID- 4140769 TI - The messenger-like properties of the poly(A)plus RNA in mammalian mitochondria. PMID- 4140770 TI - Isolation from BALB/c mouse cells of a structural polypeptide of a third endogenous type C virus. PMID- 4140771 TI - Current policies of radiation therapy of breast cancer. PMID- 4140772 TI - Multicentric and multifocal urothelial tumors. PMID- 4140773 TI - The perineal shot: demonstration of prostatic size during urography. PMID- 4140774 TI - Precommitment in the immune system. PMID- 4140775 TI - [Surgical treatment of diverticulum diseases of the colon - single or multiple resection]. PMID- 4140776 TI - Cytological studies on the organization of DNA in giant trophoblast nuclei of the mouse and the rat. PMID- 4140777 TI - Electron microscope observations of the organisation of chromatin fibers in isolated nuclei of of rat liver. PMID- 4140778 TI - A simple method to sequentially reveal Q-and C-bands on the same metaphase chromosomes. PMID- 4140779 TI - Comparative analysis of the polytene chromosomes of Glossina austeni and Glossina morsitans morsitans. PMID- 4140780 TI - [Child play and its significance]. PMID- 4140781 TI - [Significance in the involvement of intrahepatic bile ducts for the genesis of icterus and cholestasis in viral hepatitis]. PMID- 4140782 TI - Albumin catabolism measurement by a double tracer technique in uraemic patients during a single dialytic treatment. PMID- 4140783 TI - Possible participation of insulin in the control of vascular permeability. PMID- 4140784 TI - The anatomy and fine structure of the eye in teleost. II. The vascular connections of the lentiform body in Fundulus grandis. PMID- 4140785 TI - Nephrotoxic and pneumotoxic antibodies and their acute action on lungs. II. Acute pulmonary lesions and lethal effects of these antibodies in rats. PMID- 4140786 TI - [Semiquantitative histological analysis in experimental pyelonephritis of the rabbit (20-days-series and 31-days-series) (author's transl)]. PMID- 4140787 TI - Influence of oral contraceptives on the rat exocrine pancreas. A histologic, histochemical, and electron microscopic study. PMID- 4140788 TI - [Effect of solanum melongena on experimental atheromatosis. V. Electron microscopic observations on cholesterol-induced atheromatosis in rabbits in mean- and long-term tests (author's transl)]. PMID- 4140789 TI - [Pattern recognition of cell nuclei: influence of inherent errors in scanningcytophotometry (author's transl)]. PMID- 4140790 TI - DNA-Feulgen value in brain cells of the adult worker honeybee dependent on age. PMID- 4140791 TI - [Experimental studies on the development of the thoracic wall in chick embryos]. PMID- 4140792 TI - Are there any nonspecific large molecule-large molecule interactions? PMID- 4140793 TI - A simple technique for demonstrating heterochromatin in Nigella. PMID- 4140794 TI - Detection of fungal spore antigens by serologic methods. PMID- 4140795 TI - Entry of radioactivity from methyl-labeled methionine into mitochondrial and cytoplasmic RNA of cultured hamster cells. PMID- 4140796 TI - Electrophoretic separation of proteins on cellulose acetate: a technique for the study of prostatic and vesicular contributions in human seminal fluid. PMID- 4140797 TI - The expression of H-2 and differentiation antigens on mouse spermatozoa. PMID- 4140798 TI - Effect of simultaneous administration of antibiotics and TEPA on the realization of potential chromosome breaks as translocation in Drosophila melanogaster. PMID- 4140799 TI - Interactions of lymphoid cells with transplantation antigens bound to immunoadsorbent. PMID- 4140800 TI - [Oligo-anuria in female genital carcinoma (author's transl)]. PMID- 4140801 TI - Immunological relatedness among reptilian, avian, and mammalian pituitary luteinizing hormones. PMID- 4140802 TI - Comparative immunochemical studies of chicken ultimobranchial calcitonin. PMID- 4140803 TI - A cytological study on the structure of the pituitary gland of Monopterus albus (Zuiew). PMID- 4140804 TI - [Basis of the hygienic norms for the levels of a series of pesticides in the soil]. PMID- 4140805 TI - An attempt to induce myelofibrosis in rabbits by saponin injections. PMID- 4140806 TI - Inhibition of fibrinolysis by the human vascular wall related to the presence of smooth muscle cells. PMID- 4140807 TI - [The reproducibility of hematological products, microscopy and interpretation as well as its value for standardization and automation]. PMID- 4140808 TI - [The appearance of Auer-rods within Auer-globes]. PMID- 4140809 TI - [Proposal for the standardization of the absolute count of basophil granulocytes]. PMID- 4140810 TI - [The behavior of the serum iron level in children with lymphogranulomatosis]. PMID- 4140811 TI - [The cytology of transudates. 1. The cytomorphology of pleural transudates]. PMID- 4140812 TI - [The cytology of transudates. 2. The capability of phagocytosis in transudate cells]. PMID- 4140813 TI - [Leukocyte alkaline phosphatase in lymphoreticular neoplasms]. PMID- 4140814 TI - [Pathogenesis and differential diagnosis of antibody deficiency syndromes in the adult]. PMID- 4140815 TI - [Clinical valve of quantitative immunoglobulin determinations]. PMID- 4140816 TI - [Erythropoietins]. PMID- 4140817 TI - [Modification of erythrocyte resistance by polyenylphosphatidylcholine]. PMID- 4140818 TI - [Mechanism of rabbit platelet aggregation inhibition induced by cobalt(II)-ions]. PMID- 4140819 TI - [Thrombocyte function during the use of immunosuppressive agents]. PMID- 4140820 TI - [The effect of cytostatic drugs on blood platelets and lymphocytes in patients with neoplasms]. PMID- 4140821 TI - [Pathogenesis of blood coagulation disorders in chronically asphyctic newborn infants]. PMID- 4140822 TI - [Quantitative determination of fibrinolytic degradation products by means of electroimmunodiffusion]. PMID- 4140823 TI - [Blood coagulation studies in essential hyperlipoproteinemia with special reference to thrombocyte kinetics]. PMID- 4140824 TI - [Epidemiology of post transfusion hepatitis]. PMID- 4140825 TI - [History of UV therapy]. PMID- 4140826 TI - [Molecular origin of the effects of light on nucleic acid metabolism]. PMID- 4140827 TI - [The effect of ultraviolet irradiation of the blood on the blood picture]. PMID- 4140828 TI - Effect of prolonged ingestion of polychlorinated biphenyls on the rat. PMID- 4140829 TI - Liver response tests. IX. Cytopathological changes in the enlarged but histologically normal rat liver. PMID- 4140830 TI - The behavior of ring chromosome 13. PMID- 4140831 TI - Monosomy for the centromeric and juxtacentromeric region of chromosome 21. PMID- 4140832 TI - Tentative localization of a Hageman (Factor XII) locus on 7q, probably the 7q35 band. PMID- 4140833 TI - 1q plus variants in a normal adult population (one with a pericentric inversion). PMID- 4140834 TI - Malformative syndrome with ring chromosome 13. PMID- 4140835 TI - Partial trisomy 8: trisomy of the distal part of the long arm of chromosome number 8 plus (8q2) in a severely retarded and malformed girl. PMID- 4140836 TI - Trisomy 12p due to familial t(12p-,6q plus) translocation. PMID- 4140837 TI - A triploid human abortus due to dispermy. PMID- 4140838 TI - Labelling of human chromosomes with 3H-AMD. PMID- 4140839 TI - A familial reciprocal translocation between three chromosomes. PMID- 4140840 TI - Letter: A comment to the paper: Variations in normal human chromosomes, Humangenetik 22,1--15(1974). PMID- 4140841 TI - Observations with G bonding of human chromosomes. Reduction of dye concentration in Soerensen buffered solutions is sufficient for demonstrating G bands. PMID- 4140842 TI - Marker chromosomes in parents of spontaneous abortuses. PMID- 4140843 TI - Possible complex translocation t(9;14;13) (q12;pl?;Q31) in mother of a child with 9-p trisomy syndrome. PMID- 4140845 TI - Mitomycin-C therapy in advanced gastrointestinal malignant tumours. PMID- 4140844 TI - Surgery-ends and means. The Fifth Annual Borges Memorial Oration (March 1974). PMID- 4140846 TI - Studies on the therapeutic use of mercurascan (MSC). Part 2: Antiarrhythmogenic and haemodynamic effect of MSC in experimental myocardial ischaemia. PMID- 4140847 TI - Human prostatic adenoma and carcinoma in cell culture: the effects of androgen free culture medium. PMID- 4140848 TI - Immunogenicity of spermatozoa. PMID- 4140849 TI - The autoimmune response to male reproductive tissues of rabbits. III. Effects of testosterone and estrogen on cryoimmunogenic and immunochemical expressions of the central accessory glands. PMID- 4140850 TI - Virion transcriptase activity of influenza virus isolates. PMID- 4140851 TI - Interconversion of molecular size of the DNA polymerase from Rauscher leukemia virus. PMID- 4140852 TI - Viral subtypes and cross-protection in hepatitis B virus infections of chimpanzees. PMID- 4140853 TI - Measurement of mercury vapor concentrations in urban atmospheres. PMID- 4140854 TI - Clinical significance of increased serum myoinositol levels. PMID- 4140855 TI - GM polymorphism and leukemia. PMID- 4140856 TI - Effects of protein source, goitrogens and iodine level on performance and thyroid status of pigs. PMID- 4140857 TI - Serum and pituitary LH concentrations in ewes infused with LH-RH/FSH-RH. PMID- 4140858 TI - Editorial: The cytology and the cytochemistry of acute leukaemias. PMID- 4140859 TI - [Surgical treatment of simple transposition of great vessels using Mustard's operation. Study of 50 cases]. PMID- 4140860 TI - The first born. PMID- 4140861 TI - A gas chromatographic-mass spectrometric study of organic compounds adsorbed on particulate matter from diesel exhaust. PMID- 4140862 TI - Studies on the nature of non-specific staining in nitro-blue tetrazolium detection of dehydrogenases in poly acrylamide gel electrophoresis ("nothing dehydrogenase"). PMID- 4140863 TI - A simple method for the clinical determination of the mitotic activity of the human prostate in vitro. AB - Patients with a hyperplastic prostate were studied for the epithelial mitotic activity of adenomatous tissue by the (3)H-thymidine labelling method. A simple method in vitro was improved for biopsy samples. The mitotic activities obtained in vitro were compared with those obtained in vivo. The results show that the mitotic activity is not affected by the short incubation of the samples in Tyrode's balanced salt solution. PMID- 4140864 TI - A simple and rapid method for the differentiation of the members of the genus Klebsiella. PMID- 4140865 TI - Proceedings: A simplified approach to metabolic bone disease. PMID- 4140866 TI - Proceedings: Granulomatous orchitis due to histoplasma capsulatum masquerading as sperm granuloma. PMID- 4140867 TI - Persistence of chlorpyrifos-methyl in corn silage and effects of feeding dairy cows the treated silage. PMID- 4140868 TI - Foods and nutrition in a Black Studies program. PMID- 4140869 TI - Ultrastructural study of membrane-bound enzymes in thymocytes. PMID- 4140870 TI - A more sensitive and specific histochemical peroxidase stain for the localization of cellular antigen by the enzyme-antibody conjugate method. PMID- 4140871 TI - Problems of specificity in the use of a strontium capture technique for the cytochemical localization of ouabain-sensitive, potassium-dependent phosphatase in mammalian renal tubules. PMID- 4140872 TI - A morphological study of the epithalamus and the thalamus of Xenopus laevis. PMID- 4140873 TI - [Qualitative and quantitative studies on the cerebellar nuclei in Felidae]. PMID- 4140874 TI - The comparative anatomy of the telencephalon of the hagfish, Myxine glutinosa. PMID- 4140875 TI - Relations between some structural parameters of types and forms of neurons effecting different kinds of switches in the neocortex. PMID- 4140876 TI - Subcortical projections of the cingulate gyrus in cat. PMID- 4140877 TI - Pain and its management. PMID- 4140878 TI - Tropical canine pancytopenia: Clinical, hematologic, and serologic response of dogs to Ehrlichia canis infection, tetracycline therapy, and challenge inoculation. PMID- 4140879 TI - Multiple myeloma in Iowa. PMID- 4140880 TI - [Properties of the mutant of Escherichia coli which can be induced to synthesize colicin E1 by macromolecular antibiotics (author's transl)]. PMID- 4140881 TI - [Membranes in the biosynthesis of lipopolysaccharides (author's transl)]. PMID- 4140882 TI - [Removal of infected dentin using fuchsin staining as a guide. 2. Experiment with vital carious teeth (author's transl)]. PMID- 4140883 TI - Fetomaternal transfusion: a case report. PMID- 4140884 TI - Letter: Lamellated bodies in the adepidermal space of the frog tadpole skin. PMID- 4140885 TI - Binding of thyroid hormone in rabbit serum: definition of a prealbumin and effects of strain variation on binding. PMID- 4140886 TI - Function of the anuran conus arteriosus. PMID- 4140887 TI - Histological studies of skin carrying bite marks. PMID- 4140888 TI - Study on the parafollicular cells in the thyroid gland of hamsters by lead hematoxylin staining technics. PMID- 4140889 TI - Preliminary studies on the control of Japanese encephalitis vectors in Taiwan by chemical means. PMID- 4140890 TI - Radioimmunoassay of the group-specific antigen in detection of avian leukosis virus infection. PMID- 4140891 TI - Conservation of weight with the mentally retarded. PMID- 4140892 TI - Spectrophotometry of cerebrospinal fluid in subacute and chronic subdural haematomas. AB - Spectrophotometric examinations were performed on cerebrospinal and subdural fluids in subacute (five patients) and chronic (20 patients) subdural haematomas, with special reference to the diagnostic aid of CSF spectrophotometry. Spectrophotometric xanthochromia of haemorrhagic origin was found in all CSFs examined, while definite visible xanthochromia was observed in only 28% and the CSF was judged as colourless in 52% of those cases. Characteristic bleeding patterns were found spectrophotometrically in all the 20 CSFs examined within 24 hours after lumbar puncture, haematoma patterns being detected in 90-95% of the cases. In many cases the electrophoretically separated protein fractions of CSF and subdural fluids were spectrophotometrically examined. In conclusion, CSF spectrophotometry is a simple, fast, and extremely sensitive method, which in our opinion should be used routinely in the diagnosis of suspected subdural haematomas, if lumbar puncture is not contraindicated. PMID- 4140893 TI - Protein pattern or cerebrospinal fluid in spasmodic torticollis. AB - The protein patterns found on isoelectric focusing and quantitative paper electrophoresis of cerebrospinal fluid were studied in three patients with spasmodic torticollis. Very alkaline end fractions were found on isoelectric focusing in the CSF-gammaglobulin region in each case. Alkaline end fractions in the CSF-gammaglobulin region with similar or same isoelectric points have also been observed in other extrapyramidal disorders, particularly Huntington's chorea, and in other neurological diseases, especially in multiple sclerosis. It has to be shown if these alkalline end fractions consist of the same or different compounds, conceivable constituents being mentioned. Examination of the CSF protein pattern might help to distinguish organic from hysterical torticollis. PMID- 4140894 TI - A study of the distribution of mitochondria in some oxidative muscle fibres of the pig. PMID- 4140895 TI - Central neuroblastoma induced by transplacental administration of methylnitrosourea in Wistar-R rats. An electron microscopic study. PMID- 4140896 TI - Clinical studies of multiple sclerosis in Japan. Multiple sclerosis starting with retrobulbar neuritis. PMID- 4140897 TI - [Paroxysmal dysarthria and ataxia. A pathognomonic seizure syndrome in multiple sclerosis (author's transl)]. PMID- 4140898 TI - [Dental aspects of facial pain, particularly trigeminal neuralgia (author's transl)]. PMID- 4140899 TI - [Cerebral metastases from an ectopic chorionepithelioma in man. A contribution to the differential diagnosis of intracerebral hemorrhage (author's transl)]. PMID- 4140900 TI - [Uraemic polyneuropathy after renal transplantation (author's transl)]. PMID- 4140901 TI - [Pre- and postoperative occlusion of cerebral arteries in a case of sphenoidal meningioma with angiographically demonstrated chorioideal anastomosis through the chorioideal posterior artery (author's transl)]. PMID- 4140902 TI - Current approaches in the treatment of malignant gliomas of the brain. PMID- 4140903 TI - The patient that mattered. PMID- 4140904 TI - The berry aneurysm patient: the surgical management--from hemorrhage to follow up. PMID- 4140905 TI - [Nursing care of the anesthetized patient]. PMID- 4140906 TI - Possible antagonism of amphetamine by decongestant-antihistamine compounds. PMID- 4140907 TI - The effect of lithium on thyroid functioning: a controlled study. PMID- 4140908 TI - [Retrograde urethrography in a standing position. Principle. Technic. Results]. PMID- 4140909 TI - Familial mental retardation in a family with an inherited chromosome rearrangement. PMID- 4140910 TI - Chromocentres in polymorphs as interphase markers for chromosomes having increased constitutive heterochromatin. PMID- 4140911 TI - Trisomy 21 mosaicism in a woman with two children with trisomy 21 Down's syndrome. PMID- 4140912 TI - Three generations and seven family members with a t(21q22q) chromosome. PMID- 4140913 TI - Karyotype 45,XX,-21/46,XX,21q-in an infant with symptoms of G-deletion syndrome I. PMID- 4140914 TI - Evaluation of multimedia self-teaching programs for medical students taking community preceptorships. PMID- 4140915 TI - Preparation and characterization of plasma membrane of cardiac tissue. PMID- 4140916 TI - Calcium-movement controlling cardiac contractility II. Analog computation of cardiac excitation-contraction coupling on the basis of calcium kinetics in a multi-compartment model. PMID- 4140917 TI - [Action of tranexamic acid on pre and post-operative bleeding after prostatic adenomectomy (double blind study)]. PMID- 4140918 TI - [Radioisotope methods of metastases localization in urologic cancers]. PMID- 4140919 TI - [Our experience in the chemotherapy of urologic cancers and its complications]. PMID- 4140920 TI - [Treatment of pain in bone metastases of prostatic carcinoma through unilateral left adrenalectomy]. PMID- 4140921 TI - [Urologic cancer metastases. Conclusions of the forum]. PMID- 4140922 TI - [Mictiography]. PMID- 4140923 TI - [Value of flow measurements in the evaluation of lower urinary obstruction in man]. PMID- 4140924 TI - [Results, early and secondary complications of cryogenic surgery without direct vision. Prevention]. PMID- 4140925 TI - [Systemic chemotherapy in bladder tumors]. PMID- 4140926 TI - [Action and production of diphtheria toxin, with special reference to its analysis using the cross-reacting toxin material]. PMID- 4140927 TI - [Studies on Naphthol-AS-D-chloroacetate esterase staining on blood cells-as a staining distinguishing between neutrophils and monocytes (author's transl)]. PMID- 4140928 TI - [Action of anti-arrhythmic beta-blockaders]. PMID- 4140929 TI - [Treatment of extrasystole (ventricular and atrial extrasystoles)]. PMID- 4140930 TI - [Treatment of arrhythmia at coronary care units]. PMID- 4140931 TI - [Current status of the cardiac pacemaker]. PMID- 4140932 TI - [Variant alkaline phosphatase in human gastric cancer (auther's transl)]. PMID- 4140933 TI - [Gastric xanthomatosis observed in rabbits fed on a cholesterol diet and chlormadinone acetate]. PMID- 4140935 TI - Quantitative and qualitative analyses of the antibody response of adult mice tolerized with deaggregated bovine gamma-globulin. I. At the serum antibody level. PMID- 4140934 TI - Nitroblue tetrazolium (NBT)-dye test and the myeloperoxidase reaction of human leukocytes. PMID- 4140936 TI - Quantitative and qualitative analyses of the antibody response of adult mice tolerized with deaggregated bovine gamma-globulin. II. At the cellular level. PMID- 4140937 TI - [Bedside nursing. Terminal care and peaceful death. Nursing of an aged female patient from the time of her gastrectomy till her final moments]. PMID- 4140938 TI - [Nursing in the coronary care unit. 4. A case of myocardial infarct with coronary insufficiency and "R on T" type extrasystole]. PMID- 4140939 TI - [Rehabilitation nursing of patients with chronic diseases. Follow-up nursing of peptic ulcer patients with post-gastrectomy complications]. PMID- 4140940 TI - [Preoperative and postoperative nursing of cataract patients]. PMID- 4140941 TI - Prolonged intra-aortic infusion therapy with anti-tumor agents for advanced cancer of the stomach, colon and rectum. PMID- 4140942 TI - [Nursing in surgery of newborn infants. 2]. PMID- 4140943 TI - [Nursing in pediatric surgery. 6. Trauma, burns and nursing]. PMID- 4140944 TI - [Immunological basis of advantages of the swine cardiac valves over calf cardiac valves in xenotransplantation into the man]. PMID- 4140945 TI - [Disorders of cardiac rhythm and their prognostic significance after myocardial infarct]. PMID- 4140946 TI - [Optimal parameters of dual heart stimulation]. PMID- 4140947 TI - [Autoimmune reactions and blood coagulation status in patients with myocardial infarct]. PMID- 4140948 TI - [Rehabilitation of patients after surgical treatment of vasorenal hypertension]. PMID- 4140949 TI - [Current status and prospects for use of hyperbaric oxygenation in cardiac surgical practice]. PMID- 4140950 TI - [Reverse transcriptase activities in human plasma of malignant states (author's transl)]. PMID- 4140951 TI - [Acute viral pneumonia]. PMID- 4140952 TI - [Serotonin level in patients with bronchial asthma in connection with treatment by histaglobulin and corticosteroids]. PMID- 4140953 TI - [The fate of blood plasma enzymes (literature survey)]. PMID- 4140954 TI - [Method of identification of certain enzymes with the aid of their diffusion in agar gel with substrates]. PMID- 4140955 TI - [Method of determination of the activity of creatine kinase in the blood serum]. PMID- 4140956 TI - [Testing of experimental sample of the Soviet-made set of reagents for determination of the activity of aminotransferases in the blood serum (Raitman Frenkel method)]. PMID- 4140957 TI - [Determination of hydrophobic organic phosphorus cholinesterase inhibitors in the blood]. PMID- 4140958 TI - [Activity of blood serum enzymes in viral hepatitis in patients of different age]. PMID- 4140959 TI - [Certain methods of determination of blood ammonia (literature survey)]. PMID- 4140960 TI - [Determination of urea in the blood serum by "Uranal" test]. PMID- 4140961 TI - [Determination of fibrinolytic activity of blood]. PMID- 4140962 TI - [Determination of the content of antiheparin factor of thrombocytes in the plasma]. PMID- 4140963 TI - ["Bacteriostatic test"- a method of the study of microbial sensitivity to antibiotics]. PMID- 4140964 TI - [Agglutination by certain viruses of erythrocytes, treated with trypsin]. PMID- 4140965 TI - [Method of standardization of the results of titration of Rickettsia of the typhoid group on chick embryo]. PMID- 4140966 TI - [Chick embryos as a model for studying colicine biosynthesis in bacteria of the enteric family]. PMID- 4140967 TI - [Sets of chemical reagents - an active medium of work standardization in the laboratories]. PMID- 4140968 TI - [Colorimetric method of determination of phosphohexose isomerase with the aid of anthrone reagent]. PMID- 4140969 TI - [Method of determination of peptidase activity]. PMID- 4140970 TI - [Hyperfibrinogemia in malignant tumors in children]. PMID- 4140971 TI - [Dynamics of the indicators of coagulogram and thrombelastogram during 24-hour period in patients with stenocardia]. PMID- 4140972 TI - [Electrode-accumulator for the EFM-1 apparatus]. PMID- 4140973 TI - [Method of washing of bacteriological equipment]. PMID- 4140974 TI - [History of laboratory service in Russian medicine]. PMID- 4140976 TI - DNA microdensitometry as a measure of cycling-non-cycling activity in aged human diploid cells in culture. PMID- 4140975 TI - The discoveries of vitamin K and dicumarol and their impact on our concepts of blood coagulation. PMID- 4140977 TI - Letter: death and coronary attacks after giving up cigarette smoking. PMID- 4140978 TI - Antibodies to pancreatic islet cells in insulin-dependent diabetics with coexistent autoimmune disease. PMID- 4140979 TI - Portal hypertension with varices in unusual sites. PMID- 4140980 TI - Infusion of angiotensin-II analogue in two patients with unilateral renovascular hypertension. PMID- 4140981 TI - Amoebic infection of the eye. PMID- 4140982 TI - Inadequate antibody response to HBAg or suppressor T-cell defect in development of active chronic hepatitis. PMID- 4140983 TI - Inadequate antibody response to hBAg or suppressor T-cell defect in development of active chronic hepatitis. PMID- 4140984 TI - Decreased glucagon activity: A mechanism for genetic and acquired endogenous hyperlipaemia. PMID- 4140985 TI - Editorial: Autoimmune diabetes mellitus. PMID- 4140986 TI - Editorial: Kuru, Creutzfeldt-Jakob, and scrapie. PMID- 4140987 TI - Editorial: Oral bacterial vaccine and colds. PMID- 4140988 TI - Editorial: Too good to die. PMID- 4140989 TI - Editorial: Tryptophan and serotonin in Down syndrome. PMID- 4140990 TI - Quality and quantity in chemical pathology. PMID- 4140991 TI - Diphtheria in the Manchester area 1967-1971. PMID- 4140993 TI - Letter: Death and coronary attacks after giving up cigarette smoking. PMID- 4140992 TI - Letter: Reduction of sudden Deaths after myocardial infarction. PMID- 4140994 TI - Letter: Effect of surgery on lymphocytotoxicity against tumour cells. PMID- 4140995 TI - Letter: Treatment of malignant melanoma. PMID- 4140996 TI - Letter: Yersinia enterocolitica infection and thyroid disorders. PMID- 4140997 TI - Letter: Doctors, money, and N. H. S. PMID- 4140998 TI - Letter: Social workers in the primary-care team. PMID- 4140999 TI - Letter: Iron deficiency and infection. PMID- 4141000 TI - Letter: Priapism during regular dialysis. PMID- 4141001 TI - Letter: Errors of lead analyses: dependability of laboratories and clinicians. PMID- 4141002 TI - Letter: the specialty of infectious disease. PMID- 4141003 TI - Letter: Aetiology of systemic lupus erythematosus. PMID- 4141004 TI - Letter: Lupus erythematosus, D. N. A. antibodies, and suppression of erythropoiesis. PMID- 4141005 TI - Letter: are rauwolfia alkaloids carcinogenic? PMID- 4141006 TI - Letter: Rauwolfia derivatives and breast cancer. PMID- 4141007 TI - Letter: Control of respirator-associated infections. PMID- 4141008 TI - Letter: Immunosuppressive treatment of rapidly progressive glomerulonephritis. PMID- 4141009 TI - Letter: Preoperative hydration in chronic renal failure. PMID- 4141010 TI - Letter: Dispersal of Staphylococcus aureus. PMID- 4141011 TI - Letter: HL-AS and the immune response to gluten. PMID- 4141012 TI - Letter: Endoscopic liver biopsy. PMID- 4141013 TI - Letter: Muscle biopsy in Crohn's disease. PMID- 4141014 TI - Letter: Epidemic of aortic aneurysm? PMID- 4141015 TI - Letter: N. B. T. test in pulmonary embolism and bacterial pneumonia. PMID- 4141016 TI - Letter: Medicine in the Open University. PMID- 4141017 TI - Letter: Multiple sclerosis: vesicles at vaccination scar. PMID- 4141018 TI - Letter: Natural history of hypertension. PMID- 4141019 TI - Letter: Withdrawal of antihypertensive therapy. PMID- 4141020 TI - Letter: Double deletion of X chromosome. PMID- 4141021 TI - Letter: Transmission of carcinoembryonic antigen by transfused blood. PMID- 4141022 TI - Letter: Zollinger-Ellison syndrome in Negroes. PMID- 4141023 TI - Letter: An antigen associated with pregnancy. PMID- 4141024 TI - Letter: Mitochondria, autoimmunity, and oncogenesis. PMID- 4141025 TI - Letter: Placental transmission of L. A. T. S. protector. PMID- 4141026 TI - Letter: A new molecular defect in phenylketonuria. PMID- 4141027 TI - Letter: Ageing, T lymphocytes, and Down's syndrome. PMID- 4141028 TI - Letter: Herpes-simplex virus (type 1) transmitted to a neonate. PMID- 4141029 TI - Maurice Ernest Noel Smith. PMID- 4141030 TI - [Production and resorption of the perilymph (lymphatic pathways of the inner ear) (author's transl)]. PMID- 4141033 TI - Evaluation of an audiovisual carrel-tutorial course in clinical medicine. PMID- 4141031 TI - Inhibitors of immune reactions. PMID- 4141034 TI - The application of the negative staining technique to the study of membranes. PMID- 4141035 TI - Myelin basic proteins. PMID- 4141036 TI - Scanning electron microscope methods for the study of membranes. PMID- 4141037 TI - Basic methodology for cell culture--cell transformation. PMID- 4141038 TI - Use of antibodies of localization of components on membranes. PMID- 4141039 TI - Isolation of oxyntic cells. PMID- 4141040 TI - Methods for the study of chloroplast membranes of wild-type and mutant strains of Chlamydomonas reinhardi. PMID- 4141041 TI - [Interaction of acridine orange with Staphylococcus aureus cells]. PMID- 4141042 TI - [Cytological diagnosis of the thyroid gland]. PMID- 4141043 TI - The isolation of Chlamydia subgroup A (Chlamydia trachomatis) in irradiated McCoy cells. PMID- 4141044 TI - Immunological study of the agent responsible for subacute sclerosing panencephalitis and biochemical characterization of measles antibody in subacute scelerosing panencephalitis. PMID- 4141045 TI - Enzyme treatment of unfixed cell cultures as a means of determining different specificities of immunoglobulin-M in multiple sclerosis and measles. PMID- 4141046 TI - [Simple method for determination of urinary flow rate]. PMID- 4141047 TI - [Medical treatment of prostatic adenoma. Urinary flow data]. PMID- 4141048 TI - [Tadenan in the treatment of prostatic adenoma. Anatomo-clinical study]. PMID- 4141049 TI - [Prostatectomy in chronic leukemia]. PMID- 4141050 TI - [Double-blind test on the therapeutic effects of a prostatic extract in the clinical syndrome of prostatic adenoma]. PMID- 4141051 TI - [Treatment of prostatic adenoma with medroxyprogesterone acetate]. PMID- 4141052 TI - [Glossitis caused by Herpes Simplex virus. Histomorphological and clinical findings]. PMID- 4141053 TI - The gamma particle. A study of cell-organelle interactions in the development of the water mold Blastocladiella emersonii. PMID- 4141054 TI - [Australia-antigen (HB Ag) and hepatitis in childhood (author's transl)]. PMID- 4141055 TI - [Diagnosis, therapy and clinical course in chronic active hepatitis in childhood with special reference to immunological findings (author's transl)]. PMID- 4141056 TI - [Methods and results of the determination of 25-OH-vitamin D3 in competitive protein binding assay (author's transl)]. PMID- 4141057 TI - [Letter: Absorption of lead by plants?]. PMID- 4141058 TI - [The effect of lidoflazine on the excitation process in the resting and stress ECG in coronary patients (author's transl)]. PMID- 4141059 TI - [Clinical aspects of benign essential monoclonal gammopathy (author's transl)]. PMID- 4141060 TI - [Conservative treatment of prostatic adenoma]. PMID- 4141061 TI - [Cryosurgery of the prostate. Evaluation as a method for the treatment of obstruction of the neck of the bladder (author's transl)]. PMID- 4141062 TI - The need for a clinical teacher. PMID- 4141063 TI - Liver growth and mixed-function oxidase activity: dose-dependent stimulatory and inhibitory effects of alpha-hexachlorocyclohexane. PMID- 4141064 TI - Binding of exogenous noradrenaline by the proteins of dog plasma. PMID- 4141065 TI - Search for oncogenicity of type C particles released from mammalian cell lines transformed by avian Oncornaviruses. PMID- 4141066 TI - Detection of oncornavirus-like particles in human cell lines derived from tumours of hemopoietic tissue. PMID- 4141067 TI - Somatic cell hybrids between mouse cells and avian sarcoma virus transformed hamster cells. PMID- 4141068 TI - Correlation between the intensity of in vitro migration of peritoneal exudate cells and the quantity of nonadherent cells. PMID- 4141069 TI - Reversible hypogammaglobulinaemia after diphenylhydantoin and hydroxyzine therapy. PMID- 4141070 TI - [Significance of a pharmacological correction during a course of experimental liver disease due to low-protein diet in the rat (ultrastructural studies)]. PMID- 4141072 TI - Letter: Stilboestrol. PMID- 4141071 TI - Measuring the progress of a health service. PMID- 4141073 TI - Carcinoma of the bowel. PMID- 4141074 TI - [Substrate and significance of the so-called snail tracks of the retinal]. PMID- 4141075 TI - [Corneal changes in chronic glaucoma]. PMID- 4141076 TI - [Proceedings: Inductive and noninductive effect of interferon containing preparations]. PMID- 4141077 TI - [Chromolipids]. PMID- 4141078 TI - [Intensity of formation of antigammaglobulins in healthy children after administration of different doses of gamma globulin]. PMID- 4141079 TI - [Certain problems of pathogenesis and therapy of neurodermatitis and eczema in childhood]. PMID- 4141080 TI - Organochlorine insecticide residues in carpeting. PMID- 4141081 TI - [Whipple's disease revealed by arthritis]. PMID- 4141082 TI - [Orthorhythmic endocardiac stimulations. Diagnostic and therapeutic significance]. PMID- 4141083 TI - [Letter: Hyperthyroidism and amiodarone. Evaluation of 10 cases]. PMID- 4141084 TI - [Letter: Significance of Australia antigen (H. B. antigen)]?14. PMID- 4141085 TI - [Letter: simultaneous presence of australia antibody and antigen with different specificities (ay antigen and anti-d antibody)]. PMID- 4141086 TI - Nursing care study: modified Wertheim's hysterectomy. PMID- 4141088 TI - Modern visual aids. PMID- 4141087 TI - Microscopy of surgical specimens. PMID- 4141089 TI - Nursing care study; Acholuric jaundice. PMID- 4141090 TI - Nursing care study; Suprapubic prostatectomy. PMID- 4141091 TI - Hypogammaglobulinaemia with Whipple's disease. PMID- 4141092 TI - [Current concepts of the surgical treatment of broncho-pulmonary cancer]. PMID- 4141093 TI - Episodic weakness in thyrotoxicosis. PMID- 4141094 TI - [Effect of hypofunction of the thyroid gland on the changes of haptoglobin and transferrin level in the blood serum of rats]. PMID- 4141095 TI - [Effect of physical load on the content of protein-bound iodine in the blood plasma of trained and untrained rats]. PMID- 4141096 TI - Immune responses of inbred guinea pigs to the random terpolymers poly (Glu57Lys38Tyr5) and poly (Glu51Lys34Tyr15). PMID- 4141097 TI - Histamine release from human leucocytes by concanavalin A and other mitogens. PMID- 4141098 TI - Consecutive activation of a type C RNA and polyoma virus from tumors induced by polyoma virus-transformed rat cells. PMID- 4141099 TI - Kallikrein inhibitory capacity of alpha2-macroglobulin subunits. PMID- 4141100 TI - A reduced silver stain for normal axons in the central nervous system. PMID- 4141101 TI - [Present-day instruction centers]. PMID- 4141102 TI - Impairment of the freedom to change with the acquisition of the symbolic process. PMID- 4141103 TI - Psychotherapeutic assistance to a blind boy with limited intelligence. PMID- 4141104 TI - Little Black Sambo. PMID- 4141105 TI - Death education and its effect on the death anxiety level of nurses. PMID- 4141106 TI - Public health aspects of air pollution from diesel vehicles. PMID- 4141107 TI - Elastic fibres and reticulin of mammalian muscle spindles and their functional significance. PMID- 4141108 TI - Comparison of self-rating and quantity-frequency measures of drinking. PMID- 4141110 TI - [Tumorscanning of head and neck with 57Co-bleomycine (author's transl)]. PMID- 4141109 TI - Begging and social deviance on skid row. PMID- 4141111 TI - [Hemoconcentration and staining with fluorochrome: a new method for the quantitative study of parasitemia in experimental infection of Trypanosoma cruzi]. PMID- 4141112 TI - [Thyroid function in the lingual thyroid]. PMID- 4141113 TI - Factor analysis of gross and fine motor ability in developmentally disabled children. PMID- 4141114 TI - [Is prevention of tetanus still useful?]. PMID- 4141115 TI - [Clinical importance of determination of antigens of cancerous origin]. PMID- 4141116 TI - [Anatomical documents concerning a case of Refsum's disease]. PMID- 4141117 TI - [Refsum's disease. (Course)]. PMID- 4141119 TI - [Treatment of scabies]. PMID- 4141118 TI - [Chemotherapy of Hodgkin's disease]. PMID- 4141120 TI - [Rhythm disorders in the acute phase of myocardial infarct and their treatment]. PMID- 4141121 TI - [Painful complications of myocardial infarct]. PMID- 4141122 TI - [Boric acid. Method suggested to determine in situ its presence in Crustacea]. PMID- 4141123 TI - Erythrophagocytosis by pathological erythroblasts in the Di Guglielmo syndrome. A study of 18 cases. PMID- 4141124 TI - Immunoglobulin-containing intranuclear inclusions in plasma cells in a case of IgG myeloma. PMID- 4141125 TI - [Values of colloid and liver-cell scintigraphy, as well as of laparoscopy and liver serology in the diagnosis of liver tumors]. PMID- 4141126 TI - [Filtration leukopheresis. Simple and inexpensive method of obtaining granulocytes]. PMID- 4141127 TI - [Amyloid goiter]. PMID- 4141129 TI - Comparison of tuberculosis case-finding in a high prevalence area. PMID- 4141128 TI - [Periarteritis nodosa with positive Australia antigan. Digestive perforation. Report of a case]. PMID- 4141130 TI - [Alpha chain-producing intestinal lymphoma (author's transl)]. PMID- 4141131 TI - [Feedback regulation between the levels of IgG and IgM (author's transl)]. PMID- 4141132 TI - [World population year 1974: family planning on 5 continents]. PMID- 4141133 TI - [Why don,t we use more audio-visual aids?]. PMID- 4141135 TI - Non-extractable lipids in the adipose tissues of horses and ponies affected with generalized steatitis. AB - When adipose tissues of horses and ponies affected with generalized steatitis were extracted by acetone, methanol and chloroform, non-extractable lipids were found to be present, which had become insoluble as a result of peroxidation and polymerization and had acquired autofluorescent characteristics. The origin of these lipids varies. Peroxidation occurs in three different lipid compartments, namely in the cytoplasm of the necrotized adipose cells, in the macrophagess and in the fat globules present in stroma. PMID- 4141134 TI - Possible mechanism for the fibrinolytic effect of certain bis tetrahydroisquinolines: evidence for histamine release. PMID- 4141136 TI - [Chances and results of surgery of malignant mesothelioma of the pleura (author's transl)]. PMID- 4141137 TI - [Operative treatment of primary and secondary diffuse pleural tumours (author's transl)]. PMID- 4141138 TI - [Thoracotomy and open treatment of chronic empyema as possibility for patients being otherwise inoperable (author's transl)]. PMID- 4141139 TI - Chlorphentermine-induced lipidosislike ultrastructural alterations in lungs and adrenal glands of several species. PMID- 4141140 TI - Residual effects of short-term, low-level exposure of nonhuman primates to polychlorinated biphenyls. PMID- 4141141 TI - [Radiotherapy of endocrine ophthalmopathy using 18-MeV betatron radiation]. PMID- 4141142 TI - [Gastric sarcoma]. PMID- 4141144 TI - [Adenoma and cancer of the prostate]. PMID- 4141143 TI - Burn shock. PMID- 4141145 TI - [False and true proteinuria in inflammatory diseases of the organs of the urinary system]. PMID- 4141146 TI - [Immunobiological study of colibacterial pyelonephritis]. PMID- 4141147 TI - [Analysis of postoperative mortality in adenoma of the prostate gland]. PMID- 4141148 TI - [Use of simplified uroflowmetry and indices of the functional state of the urinary bladder in prostatic adenoma]. PMID- 4141149 TI - [Gerontological problems in urology]. PMID- 4141150 TI - [Remote results of various modifications of transvesical adenomectomy of the prostate]. PMID- 4141151 TI - [Late hemorrhage following adenomectomy of the prostate]. PMID- 4141152 TI - [Use of leukocyte intoxication index for evaluation of the course of the postoperative period in patients following prostatic adenomectomies]. PMID- 4141153 TI - [Sodium and potassium content of erythrocytes at the terminal stage of chronic renal insufficiency and during treatment by chronic hemodialysis]. PMID- 4141154 TI - [Importance of the evaluation of blood filling and tonus of prostatic vessels in the diagnosis of prostatic neoplasms]. PMID- 4141155 TI - [Prostatic adenomectomy in a patient with implanted cardiostimulator]. PMID- 4141156 TI - [Protein fractions and hyaluronidase activity in the blood serum in pyelonephritis (experimental study)]. PMID- 4141157 TI - [Diverticula of the bladder: pathogenesis, clinical course and treatment (author's transl)]. PMID- 4141158 TI - [Influence of gestonoron-capronate (GC) upon uptake and metabolism of H3 testosteron in benign prostatic hypertrophy (BPH): in vivo-experiments (author's transl)]. PMID- 4141161 TI - [Antistaphylococcal gamma-globulin in the treatment of staphylococcal eye infection]. PMID- 4141162 TI - [Use of antibodies stained with horseradish with peroxidase for the determination of the presence of antigens]. PMID- 4141163 TI - Improved weight gains in pigs following treatment for sarcoptic mange. PMID- 4141164 TI - [Age-related changes in the microstructure of the skin in fine-fleeced sheep]. PMID- 4141165 TI - [Bacterial culture methods for staining flagellae]. PMID- 4141166 TI - Intraneuritic corpora amylacea. Demonstration in orbital cortex of elderly subjects by means of early postmortem brain sampling and electron microscopy. PMID- 4141167 TI - [Assuring visibility in practical exercises]. PMID- 4141168 TI - [Antiviral immunity in the child during ontogenesis]. PMID- 4141169 TI - [Clinico-morphological characteristics of Brenner tumor]. PMID- 4141170 TI - [Functional state of the thyroid gland in acute cerebro-cranial injury]. PMID- 4141171 TI - [Association of complete atrioventricular block with disorders of excitability in rheumatic heart disease]. PMID- 4141172 TI - [Synovial fluid and the importance of its examination in the diagnosis of joint diseases]. PMID- 4141173 TI - [Effect of diet therapy on the quantity of lipid-containing leukocytes in the blood in ischemic heart disease]. PMID- 4141174 TI - [Effect of chlorophos and methylnitrophos on certain immune reactions of the body against a background of protein-deficient nutrition]. PMID- 4141175 TI - [Study of the group-specific antigen of oncornavirus from human laryngeal carcinoma cells and its comparison with antigens from oncornaviruses of different origin]. PMID- 4141176 TI - [Further study of the virus of human lymphoblastoid cells J-96]. PMID- 4141177 TI - [Comparative study of antigenic relationships between rubella virus strains in conventional and kinetic hemagglutination inhibition tests]. PMID- 4141178 TI - [Agglutination reaction of antibody-sensitized erythrocytes with Colorado tick fever virus]. PMID- 4141179 TI - [Development of lyophilized test-preparations for detection of viruses in infected cells]. PMID- 4141180 TI - [Development of molecular biology and outlook for virological research]. PMID- 4141181 TI - [Study of West Nile virus antigens]. PMID- 4141182 TI - [Multiple complications of myocardial infarct]. PMID- 4141183 TI - [Disruption of the cardiac rhythm in myocardial infarct]. PMID- 4141184 TI - [Dynamics of some blood indices in activated osteoarthrosis treated with mineral oil electrophoresis (clinico-experimental study)]. PMID- 4141185 TI - [Bleomycin--a new antineoplastic antibiotic]. PMID- 4141186 TI - [Heart involvement in young patients with grippe-pneumonia, based on baalistocardiographic and electrocardiographic data]. PMID- 4141187 TI - [Functional activity of the thyroid gland in alcoholic patients]. PMID- 4141188 TI - [Total and free thyroxine in certain thyroid diseases (preliminary report)]. PMID- 4141189 TI - [Clinico-laboratory observations on 30 patients with plasmacytoma]. PMID- 4141190 TI - [Concept of endocrine ophthalmopathies]. PMID- 4141191 TI - [Chronic calciphylactic pancreatitis]. PMID- 4141192 TI - [Status and some aspects of the prevention of complications following vaccination against smallpox]. PMID- 4141193 TI - [Etiology, pathogenesis and treatment of gangrenous pyoderma]. PMID- 4141194 TI - The effect of ageing on enzyme histochemical vital reactions. PMID- 4141195 TI - [Regional variations of "elastic globes" in human skin (author's transl)]. PMID- 4141196 TI - A histological study of the adenohypophysis of the rat. 1. Evaluation of some specific staining methods. PMID- 4141197 TI - Contribution to the assessment of the pre-operative condition of the nose in patients with palatoschisis. PMID- 4141198 TI - Free-skin transplantation using the "sito" graft in the treatment of faulty stumps of the lower limb. PMID- 4141199 TI - Purpura fulminans. PMID- 4141200 TI - Formation of vagina (colpopoiesis) from peritoneum of Douglas pouch. PMID- 4141201 TI - Reconstructive surgery for faulty short amputation stumps of foot. PMID- 4141202 TI - Fractures in rhinoplasty. PMID- 4141203 TI - Tissue bank of the University Hospital in Hradec Kralove (conception, work, future). PMID- 4141204 TI - Complicated reconstruction after mutilating operation of the lip in bilateral cleft of the primary and secondary palate. PMID- 4141205 TI - Letter: Cytology of epithelioid sarcoma. PMID- 4141206 TI - Analysis of variance of the Papanicolaou staining reaction. PMID- 4141207 TI - Malignant melanoma of the vagina. A case diagnosed cytologically. PMID- 4141208 TI - Lipid peroxidation in erythrocytes. Supravital staining of peroxidised cells by crystal violet. PMID- 4141209 TI - Secondary anemia (XV) and reticuloendothelial uptake in cancer. PMID- 4141210 TI - [Immunologic abnormalities in the course of myeloid splenomegaly with myelosclerosis]. PMID- 4141211 TI - Plasma protein metabolism. PMID- 4141212 TI - Origin of the marker chromosomes in an established hypotriploid glioma cell line studies with G-band technique. PMID- 4141213 TI - Iatrogenic Crooke's changes in human pituitary gland with special reference to the correlation of cortical hormones applied. PMID- 4141214 TI - Porcine salmonellosis: a counterpart to the generalized Shwartzman reaction. PMID- 4141215 TI - Lobular carcinoma in situ. A histological study of 52 cases. PMID- 4141216 TI - Effect of ricin immunization on the qualitative compositions of plasma proteins. PMID- 4141217 TI - Hyalinosis as the cause of massive cerebral hemorrhage. PMID- 4141218 TI - Early results of intraarterial application of bleomycin, methotrexate and proresid in locally advanced head and neck tumors. PMID- 4141219 TI - Immunodiagnosis and immunization in bacterial meningitis. PMID- 4141220 TI - Pathophysiology and epidemiology of acute viral infections of the nervous system. PMID- 4141221 TI - Acid secretion and mobilization of gastric mucosal histamine on combined cholinergic and pentagastrin stimulation. PMID- 4141222 TI - Landmarks in malaria research (a review). PMID- 4141223 TI - A study of striae observed in the cornea from contact lens wear. PMID- 4141224 TI - The pathogenesis of bleomycin-induced pulmonary fibrosis in mice. AB - Administration of 0.5 mg bleomycin to mice twice weekly for 4 weeks induced pulmonary fibrosis. The initial site of injury was the intima of pulmonary arteries and veins where endothelial cells became edematous and were separated from the underlying basement membrane by large blebs. These lesions occurred after 2 weeks and were associated with infiltration of perivascular spaces by lymphocytes and plasma cells. Capillary endothelial blebbing and interstitial edema were observed after 4 weeks, when multifocal necrosis of type 1 alveolar epithelial cells was accompanied by fibrinous exudation into the alveoli. The process of repair was characterized by proliferation and metaplasia of type 2 epithelial cells, fibroblastic organization of alveolar fibrin and fibrosis of the interstitium within 8 to 12 weeks. The consistent induction of changes similar to those of diffuse pulmonary fibrosis or fibrosing alveolitis in man suggests that bleomycin-induced injury may provide a suitable model for the investigation of this ill-defined group of diseases. PMID- 4141226 TI - [Condition of the cervix in uterine prolapse]. PMID- 4141225 TI - Pathology of the pigment epithelium and retina in rabbits poisoned with lead. AB - Multifocal lesions of the retinal pigment epithelium were observed in rabbits fed a diet contaning 0.5% lead subacetate for periods of up to 2 years. Groups of pigment epithelial cells became congested with a lipofuscin pigment which was apparently derived from phagosomes of rod outer segments. Lipofuscin granules displaced melanin granules from the apical surface of the retinal pigment epithelial cells and resulted in conspicuous brown pigmentation of these cells in albino animals. Migration of macrophages and pigment epithelial cells into the subretinal space was common in affected areas. This pathology was not observed in the pigment epithelium of the ora serrata, or ciliary body. At the latest time periods, the abnormal lipofuscin pigmentation subsided, and degeneration of photoreceptors occurred. The pathogenesis of the lesions is discussed. PMID- 4141227 TI - [Diagnosis of pyelonephritis during pregnancy]. PMID- 4141228 TI - [Immunochemical indentification of beta globulin of the "pregnancy zone" in the blood serum of patients with hydatid mole and chorioepithelioma]. PMID- 4141229 TI - An improved method for the colorimetric assay of thiacetazone in pharmaceutical preparations. PMID- 4141230 TI - Fatty acids of the fat body of Pieris brassicae L. during metamorphosis; effect of a low concentration of a chlorinated insecticide. PMID- 4141231 TI - [Current nosologic concepts in malignant non-Hodgkin lymphomas]. PMID- 4141232 TI - [Ultrastructural and histochemical study of bacterial destruction in 2 cases of Whipple's disease]. PMID- 4141233 TI - [Staining technics for tissues osmium-fixed and embedded in araldite and epon]. PMID- 4141234 TI - [Presence of virus-like particles in a pleomorphic strain of Penicillium citrinum]. PMID- 4141235 TI - [Enhancement of section contrast in electron microscopy]. PMID- 4141236 TI - [Treatment of sequellar oculomotor paralyses]. PMID- 4141237 TI - In-vitro culture of Kaposi's disease cells. PMID- 4141238 TI - Bovine babesiasis: computer simulation of Babesia argentina parasite rates in Bos taurus cattle. PMID- 4141239 TI - The use of BCG as a source of acid and alcohol fast bacilli for staining purposes. PMID- 4141240 TI - Tubular complex of small lymphocytes in lymphatic tissues of the mouse. PMID- 4141241 TI - Role of easily released substances (ERS) from bacteria into physiologic solutions in natural immunity. V. Antigenic relation of bacterial ERS and human gamma globulins of the Gm and InV systems. PMID- 4141242 TI - [Tuberculosis by non-acid-fast Mycobacterium. Demonstration and isolation of two strains (author's transl)]. PMID- 4141243 TI - Ultrastructural observations on the keratohyalin granules of the rat oral epithelium. PMID- 4141244 TI - The incidence of epithelium in periapical granulomas and the mechanism of cavitation in apical dental cysts in man. PMID- 4141245 TI - Distribution within the cochlea of dihydrostreptomycin injected into the circulation. An autoradiographic and electron microscopic study. PMID- 4141246 TI - Immediate hypersensitivity responses in the marsupial Setonix brachyurus (the quokka). Characterization of the homocytotropic antibody. PMID- 4141247 TI - The effect of burimamide, an H-2 receptor antagonist, upon the general and coronary haemodynamics of intact dogs and upon histamine release by Tween 20. PMID- 4141248 TI - A programmed individual study method for teaching veterinary radiology: a pilot study. PMID- 4141249 TI - Multiple family therapy. PMID- 4141250 TI - Genetic aspects of spermatoza. PMID- 4141251 TI - Structure of mammalian chromosomes. PMID- 4141252 TI - Chemical and structural analysis of mammalian spermatozoa. PMID- 4141253 TI - Quantitation of heterogeneous human heterochromatin: microdensitometric analysis of C-and G-bands. PMID- 4141254 TI - A new method for staining for peptidase on polyacrylamide gels. PMID- 4141256 TI - Intra-axonal transport in noradrenergic neurons in the sympathetic nervous system. PMID- 4141255 TI - Ionophore-mediated coupling between ion fluxes and amino acid absorption in mouse ascites-tumour cells. Restoration of the physiological gradients of methionine by valinomycin in the absence of adenosine triphosphate. AB - 1. Preparations of mouse ascites-tumour cells depleted of ATP and Na(+) ions accumulated l-methionine, in the presence of cyanide and deoxyglucose, from a 1mm solution containing 80mequiv. of Na(+)/l and about 5mequiv. of K(+)/l. Valinomycin increased, from about 4 to 16, the maximum value of the ratio of the cellular to extracellular concentrations of methionine formed under these conditions without markedly affecting the distributions of Na(+) and of K(+). Similar observations were made with 2-aminoisobutyrate, glycine and l-leucine. Increasing the extracellular concentration of K(+) progressively decreased the accumulation of methionine in the presence of valinomycin. Over the physiological range of ionic gradients, the system behaved as though the absorption of methionine with Na(+) was closely coupled to the electrogenic efflux of K(+) through the ionophore. The process was insensitive to ouabain and so the sodium pump was probably not involved. 2. The amount of methionine accumulated during energy metabolism was similar to the optimal accumulation in the presence of valinomycin when ATP was lacking. It was also similarly affected by increasing the methionine concentration. 3. A mixture of nigericin and tetrachlorosalicylanilide mimicked the action of valinomycin. The anilide derivative inhibited the absorption of 2-aminoisobutyrate in the presence of valinomycin, but not in its absence. 4. Gramicidin inhibited methionine absorption and caused the preparations to absorb Na(+) and lose K(+). 5. The observations appear to verify the principle underlying the gradient hypothesis by showing that the tumour cells can efficiently couple the electrochemical gradient of Na(+) to the amino acid gradient. PMID- 4141257 TI - [AC-polarographic determination of thioacetazone and its decomposition products in biological material]. PMID- 4141258 TI - Comparative effect of imolamine, lidocaine and disopyramide on experimental rhythm disorders and auriculoventricular conduction. PMID- 4141259 TI - Clinical experience with euthroid: a new drug for thyroid replacement therapy. PMID- 4141260 TI - A follow-up study of nineteen alcoholic patients treated by means of tetraethyl thiuram disulfide (antabuse) implants. PMID- 4141261 TI - The colony forming efficiency of single cells and cell aggregates from a spontaneous mouse mammary tumour using the lung colony assay. AB - Single cell suspensions of spontaneous C3H mammary tumours did not produce colonies in the lungs of syngeneic mice after intravenous injection whereas cell aggregates obtained from similar tumours did. The number of colonies formed after the injection of aggregates was related to aggregate size and was proportional to the number injected.Single cells grew in an intramuscular site and in vitro and it was also found that if spontaneous tumours were passaged in vivo a few times single cells would grow in the lung. PMID- 4141262 TI - Incidence of carcinoma of stomach and tumour type. PMID- 4141263 TI - A spontaneous glomerular lesion in the Syrian hamster (Mesocricetus auratus). PMID- 4141264 TI - The autonomic control of colonic mucin secretion in the mouse. PMID- 4141265 TI - The molecular organization of the very rapidly renaturing DNA sequences in Drosophila melanogaster: further evidence for a class of non-satellite simple sequence DNA. PMID- 4141266 TI - [Heterogenic antigens of E. coli genetic recombinants similar to human A, B, and O antigens]. PMID- 4141267 TI - [The influence of inhibitory and facilitory structures in the medulla oblongata on segmental reflexes in experimental thyrotoxicosis]. PMID- 4141268 TI - [A modification of Peters' method for application to cytologic studies]. PMID- 4141269 TI - [The effect of the severity of a sustained terminal condition on endocrine gland function in the early postresuscitation period]. PMID- 4141270 TI - [Passive transmission of experimental allergic encephalomyelitis by serum anti brain antibodies]. PMID- 4141271 TI - Autonomic neuroreceptor mechanisms in brain vessels. PMID- 4141272 TI - [Neurospecific antigen without species specificity]. PMID- 4141273 TI - [Relative importance of hypothalamic lesions induced by aurothioglucose in normally fed and fasting mice]. PMID- 4141274 TI - [Changes in sleep-wakefulness rhythms after injection of albumin or gamma globulin in lethally irradiated rats]. PMID- 4141275 TI - The organic-inorganic relationships in bone matrix undergoing osteoclastic resorption. PMID- 4141276 TI - Histochemical studies on calcified tissues. II. Amino acid histochemistry of developing dentine and bone. PMID- 4141277 TI - Giemsa banding of the chromosomes of the domestic sheep (Ovis aries). PMID- 4141278 TI - Chromosome structure in Chilocorus (Coleoptera: Coccinellidae). I. Fluorescent and Giemsa banding patterns. PMID- 4141279 TI - A preschool screening program on central Vancouver Island: a two-year follow-up. PMID- 4141280 TI - Phase I study of twice weekly 5-azacytidine (NSC-102816). PMID- 4141281 TI - The ultrastructure of the skin of Tilapia mossambica (Peters). PMID- 4141282 TI - Possible mechanisms determining synapse formation in developing skeletal muscles of the chick. PMID- 4141283 TI - Substrate-histochemical investigations and ultrahistochemical demonstrations of acid phosphatase in larval and prepupal salivary glands of Drosophila melanogaster. PMID- 4141284 TI - On pigment-loaded stellate cells within layer II and III of the human isocortex. PMID- 4141285 TI - Ultrastructural and cytochemical studies of perifollicular mesenchyme in the thyroid gland of the golden hamster. PMID- 4141286 TI - [Treatment of hyperthyroidism in children with antithyroid drugs and the results of T3 inhibition and TRH tests]. PMID- 4141287 TI - Methyl prednisolone in the treatment of renal transplant rejection. PMID- 4141288 TI - [Diagnosis and therapy of chronic hepatitis]. PMID- 4141289 TI - Public health under Napoleon: The Conseil de Salubrite de Paris, 1802-1815. PMID- 4141290 TI - William Bullein and the "lively fashions" in Tudor medical literature. PMID- 4141291 TI - Friedrich Hoffman and some medical aspects of witchcraft. PMID- 4141292 TI - [Jacques Ballexserd, the physician from Geneva (1726-1774) and the physical education of children]. PMID- 4141294 TI - [Origin of blood transfusion. III]. PMID- 4141293 TI - Bellini's concept of catarrh: an examination of a seventeenth-century iatromechanical viewpoint. PMID- 4141296 TI - Neonatal immunology and related protective mechanisms. PMID- 4141295 TI - Invluence of oral contraceptives on circulating immune response. II. Effect of progestogenic and estrogenic components. PMID- 4141297 TI - [Chromatid exchanges in human mitotic cells. BUDR Treatment and bichromatic fluorescence by aridine orange (author's transl)]. PMID- 4141298 TI - Differential Giemsa staining of sister chromatids and the study of chromatid exchanges without autoradiography. PMID- 4141299 TI - Giemsa technique for the detection of sister chromatid exchanges. PMID- 4141300 TI - Cytological differentiation of constitutive heterochromatin. PMID- 4141301 TI - X and Y chromosomes of Aedes aegypti (L.) distinguished by Giemsa C-banding. PMID- 4141302 TI - Banding patterns on lampbrush chromosomes of Triturua marmoratus (Amphibia Urodela) by the Giemsa stain. PMID- 4141303 TI - Comparative study of human chromosome replication in primary cultures of embryonic fibroblasts and in cultures of peripheral blood leucocytes . I. Chromosome replication at the beginning and termianation of the S PERIOD. PMID- 4141304 TI - [Effect of acetoacetylation of erythrocytes on Mott cell formation during immunization]. PMID- 4141305 TI - [Polymyalgia rheumatica and its treatment]. PMID- 4141306 TI - [The action of ajmaline bitartrate on ventricular extrasystoles after recent myocardial infarction (author's transl)]. PMID- 4141307 TI - [New cytostatics in oncological therapy]. PMID- 4141308 TI - Heterogeneity of erythrocyte catalase II. Isolation and characterization of normal and variant erythrocyte catalase and their subunits. PMID- 4141309 TI - Studies on lysostaphin. Serological cross-reactions between three isolated enzymes. PMID- 4141310 TI - [Short explanation on the pathogenesis and therapy of foot-mycoses]. PMID- 4141311 TI - PG fertility control research--maps and directory. PMID- 4141312 TI - World fertility trends, 1974. PMID- 4141313 TI - [Fertility problems in the horse]. PMID- 4141314 TI - Colon cancer: a disease of fibre depletion or of dietary excess? PMID- 4141315 TI - The X chromosomes of mammals: karylogical homology as revealed by banding techniques. AB - A comparison of the Giemsa-banding patterns of the X chromosomes in various mammalian species including man indicates that two major bands (A and B), which are resistant to trypsin and urea-treatments, are always present irrespective of the gross morphology of the X chromosomes. This is true in all mammalian species with the "original or standard type" X chromosomes (5-6% of the haploid genome) thus far analyzed. In the unusually large-sized X chromosomes the extra chromosomal material may be due either to the addition of genetically inert constitutive heterochromatin or to an X-autosome translocation. In these X chromosomes two major bands are present in the actual X-chromosome segment. Our data on C and G band patterns also support Ohno's hypothesis that the mammalian X chromosome is extremely conservative in its genetic content, in spite of its cytogenetic variability. PMID- 4141316 TI - [Nonspecific stimulation of reactivity of the body of patients during heart surgery]. PMID- 4141317 TI - Life cycle of RNA oncogenic viruses. PMID- 4141318 TI - RNA tumor viruses and human leukemias. PMID- 4141319 TI - RNA tumor viruses and human lymphomas. PMID- 4141320 TI - Biochemical evidence for the presence of RNA tumor viruses in human leukemic plasma. PMID- 4141321 TI - Relatedness of RNA and reverse transcriptase from human acute myelogenous leukemia cells and from RNA tumor viruses. PMID- 4141322 TI - Glucocorticosteroids and RNA tumor viruses. PMID- 4141323 TI - The molecular basis of gene expression. PMID- 4141324 TI - Reverse transcriptase of an oncornavirus-like particle derived from human HeLa cells. PMID- 4141325 TI - The relevance of RNA-directed DNA polymerase activity to human neoplasia. PMID- 4141326 TI - On the origin of human acute myeloblastic leukemia: virus-"hot spot" hypothesis. PMID- 4141327 TI - DNA-dependent DNA and RNA polymerases and tRNA-methyl-transferases in human leukemia and differentiating Friend virus leukemia cells. PMID- 4141328 TI - Cytology and cytochemistry of the leukemia cell. PMID- 4141329 TI - Human leukemia--an overview. PMID- 4141330 TI - Hemopoietic stem cells and leukemia. PMID- 4141331 TI - Differentiation and transformation of hematopoietic cells in culture. PMID- 4141332 TI - [Bone scan of persisting epiphyseal cartilage]. PMID- 4141333 TI - A presumptive tetrasomy for the short arm of chromosome 9. PMID- 4141334 TI - Mosaic-trisomy and pericentric inversion of chromosome 9 in a malformed boy. PMID- 4141336 TI - Partial trisomy 4q and partial monosomy 18q as a consequence of a paternal balanced translocation t(4qminus; 18qplus). PMID- 4141335 TI - [Chromatid exchange and heterochromatin alteration of human chromosomes with BUdR labelling. Demonstrated by benzimidazolfluorochrome and Giemsa stain]. PMID- 4141337 TI - Participation of D-group chromosomes in satelite associations. PMID- 4141338 TI - Social science and health policy in preindustrial society. PMID- 4141339 TI - Notes on the psychical roots of religion, with particular reference to the development of western Christianity. PMID- 4141340 TI - Aggression, error and truth. PMID- 4141341 TI - A discussion of the paper by Ernesto M. La Porta on "Agression, error and truth". PMID- 4141342 TI - The Alaskan Athabaskan potlatch ceremony: an ethnopsychoanalytic study. PMID- 4141343 TI - Diabetes associated with prostatic hypertophy and its managemnet in transvesical prostatectomy. PMID- 4141344 TI - Characterization of the major viral polypeptide in cells transformed by wild-type and temperature-sensitive murine sarcoma virus. PMID- 4141345 TI - [Picture reports: Primary lesion, ulcus phagedaenicum, lues ulcerosa, skin changes during bleomycin treatment, granuloma gangragenscens nasi]. PMID- 4141346 TI - [Spilous nevus--a pigmented nevus with giant melanosoma. Clinical aspects, histology and ultrastructure]. PMID- 4141347 TI - [Histology of the unchanged skin in the diabetic patient]. PMID- 4141348 TI - Elimination of wheat and rye chromosomes in a strain of octoploid triticale as revealed by giemsa banding technique. PMID- 4141349 TI - Cytogenetic investigations on a Ehrlich ascites tumor, and four sublines resistant to daunomycin, adriamycin, vincristine and vinblastine. PMID- 4141350 TI - Absence of longitudinal differentiation of dinoflagellate (Prorocentrum micans) chromosomes. PMID- 4141351 TI - The influence of salt on the staining of tissue sections with basic dyes: an investigation into the general applicability of the critical electrolyte concentration theory. PMID- 4141352 TI - The mechanism of false-positive lipid histochemical reactions of glutaraldehyde fixed rat adrenal medulla. PMID- 4141353 TI - The mechanism of the ferric ferricyanide reduction reaction. PMID- 4141354 TI - Histochemical observations with the light and the electron microscope on the mucosubstances of the normal mouse gallbladder epithelial cells. PMID- 4141355 TI - Anisotropy and isoelectrical point determinations on collagen bundles of the rat periodontal fibers. PMID- 4141356 TI - [On the use of chrome-gelatin and formalin-gelatin as an adhesive for tissue sections intended for treatment with performic acid (author's transl)]. PMID- 4141357 TI - Selective proteolytic sensitivity of sulfate-collagen and basement membranes. PMID- 4141358 TI - Proceedings: On neutral red staining of APUD cells. PMID- 4141359 TI - Proceedings: The distribution of chromaffin-positive (CH plus) and small intensely fluorescent (SIF) cells in rat sympathetic ganglia of different ages. PMID- 4141360 TI - Alpha-1 antitrypsin deficiency in pulmonary diseases. PMID- 4141361 TI - Electron-microscope observations on the organization of the nucleus in chicken erythrocytes and a superunit thread hypothesis for chromosome structure. PMID- 4141362 TI - Visualization of charged groups on the surface of rat liver nuclei. PMID- 4141363 TI - Structure of layer IV in the somatosensory neocortex of the rat: description and comparison with the mouse. PMID- 4141364 TI - A dicentric Robertsonian translocation in a Dexter Cow. PMID- 4141365 TI - [Surgical treatment of esophageal neoplasms with preoperative extensive radiation and administration of antineoplastic drugs]. PMID- 4141366 TI - Fast axoplasmic transport in nonmyelinated mammalian nerve fibers shown by electron microscopic radioautography. PMID- 4141367 TI - Indices for measurement of soft accumulations in clinical studies of oral hygiene and periodontal disease. PMID- 4141368 TI - The release of histamine during gastric acid secretion in conscious rats. AB - 1. Conscious gastric-cannulated rats were given [(3)H]histidine and aminoguanidine by dosage procedures intended to build up fast-turnover and slow turnover pools of tissue [(3)H]histamine. Acid secretion was stimulated by I.V. infusion of pentagastrin, and the [(3)H]histamine content of gastric juice and excretion in urine were determined at 30 min intervals.2. The amount of [(3)H]histamine in gastric juice derived from either a slow-turnover or fast turnover pool was very low in unstimulated animals, and was not altered during pentagastrin-stimulated acid secretion.3. From a slow-turnover pool pentagastrin caused increased urinary excretion of [(3)H]histamine. This was abolished by gastrectomy, so that the [(3)H]histamine liberated by pentagastrin from this pool appears to have been derived from the stomach. Evidence was not found for the existence of a slow-turnover histamine pool in the glandular mucosa of the stomach, and the source within the stomach of this pentagastrin-liberated histamine is thus uncertain.4. From a fast-turnover pool pentagastrin did not cause an increased urinary excretion of [(3)H]histamine. The amount of [(3)H]histamine excreted by gastrectomized rats was not different from that produced by gastric-cannulated animals. This suggests that a high proportion of urinary histamine derived from a fast-turnover pool was non-gastric in origin.5. Differences in the time scale of [(3)H]histamine release and acid secretion were not found. In some experiments the urinary output of [(3)H]histamine was prolonged beyond the end of pentagastrin administration and gastric acid secretion. However, the overall data do not suggest that urinary histamine output and gastric acid secretion take different time courses. PMID- 4141369 TI - Electrical responses of double cones in the turtle retina. AB - 1. Responses to monochromatic flashes were recorded intracellularly from double cones in the retina of the turtle, Pseudemys scripta elegans. Double cones have been identified by intracellular marking with Procion Yellow dye.2. The direct light response of a double cone is a hyperpolarization graded with the intensity of a flash and similar to the response of single cones.3. When flashes were dim, responses were proportional to light intensity but varied in time course as a function of wave-length. They reached peak in about 120 msec for deep red stimuli and about 143 msec for green stimuli.4. When applied over red backgrounds, responses to red flashes became smaller, faster and frequently diphasic, but responses to green remained similar to those recorded from darkness. Green backgrounds made responses to all colours small and fast.5. Linear spectral sensitivity curves have peaks corresponding to the peak sensitivities of single red-sensitive and green-sensitive cones. Red and green backgrounds suppressed red and green sensitivity respectively.6. Large fields of illumination evoked composite responses which included the direct light response, its enhancement from illumination of nearby receptors and the depolarizing effect of luminosity horizontal cell impingement. In the green-sensitive element the depolarizing effect was larger for red than for green flashes, and stimulation with red annuli evoked net depolarizing responses.7. It is concluded that the responses of double cones may be explained by coupling of the responses from red-sensitive and green sensitive elements each of which has properties otherwise similar to single red sensitive and green-sensitive cones. PMID- 4141370 TI - Protein and glucose-induced changes in sodium transport across the pig small intestine. AB - 1. The effect of glucose and of bovine gamma-globulin on short-circuit current and sodium transport was measured using new-born pig ileum before and after suckling.2. Glucose increased the short-circuit current with an apparent K(m) of 1.9 and 19.5 mM for new-born unsuckled and suckled intestines respectively. The V(max) was about 80 muA cm(-2) in each case.3. Bovine gamma-globulin applied to new-born pig ileum caused a 20% increase in sodium chloride influx without change of short-circuit current. The tissue conductance was also greater in the presence of globulin. These effects were not seen in ileum taken from suckled pigs.4. p Chloromercuriphenyl sulphonic acid (PCMPS) inhibited the globulin induced increase in sodium influx in new-born pig ileum without changing the measured short-circuit current. 0.1 mM-PCMPS also changed the characteristics of the glucose-dependent increase in short-circuit current, so that this response came to resemble that seen in ileum taken from suckled pigs. Dithioerythritol reversed this effect of PCMPS.5. The suckling-dependent difference in results is explained in terms of a change in microvillar function taking place as a consequence of long-term pinocytosis in vivo. The ability of PCMPS to simulate some of these changes suggests that sulphydryl groups might be important regulators of microvillar membrane stability. PMID- 4141372 TI - Antigens and antigenic variability of the African trypanosomes. PMID- 4141373 TI - Differentail nuclear coloration in ciliates. PMID- 4141371 TI - The ontogenetic development of concentration differences for protein and ions between plasma and cerebrospinal fluid in rabbits and rats. AB - 1. The purpose of this study was to study in rats and rabbits the ontogenetic development of the blood-brain barrier to macromolecules and the ontogenetic development of concentration differences between plasma and cerebrospinal fluid for ions which are known to be transported actively across the choroid plexus and the blood-brain barrier.2. By comparing the development of concentration differences for ions with the development of the blood-brain barrier to macromolecules we wanted to evaluate an eventual relationship between the development of these two functions of the blood-brain barrier.3. The concentration of protein in cerebrospinal fluid and plasma was measured in foetal, juvenile and adult rabbits and in new-born, juvenile and adult rats. The concentration of protein was similar in rabbit foetuses at 23 days of gestational age (term at 31 days) and in new-born rats, and the ratio decreases at approximately the same rate in the two species.4. The high concentration of proteins in cerebrospinal fluid might reflect either a high rate of entry of protein into the brain or a low production rate of cerebrospinal fluid. Injection of Diamox(R) (100 mg/kg) 2 hr before sampling of cerebrospinal fluid did not change the concentration of protein in cerebrospinal fluid in new-born rats whereas it increased the concentration in older rats. This finding suggests that new-born rat produces little (if any) cerebrospinal fluid suggesting that the high concentration of protein in cerebrospinal fluid in new-born rats reflect a low rate of turnover of cerebrospinal fluid.5. The concentration of sodium, potassium, chloride and magnesium in plasma and cisternal cerebrospinal fluid was measured in rabbits of different age, from 23 days of gestation until adulthood, and in rats of different ages from birth until adulthood.6. Concentration differences between plasma and cerebrospinal fluid for these were established in the youngest animals examined, indicating that the active transport mechanisms for these ions were functioning at an age where the concentration of protein in cerebrospinal fluid was very high.7. The maintenance of concentration differences for ions at a time where the concentration of proteins in cerebrospinal fluid is high, is difficult to explain if the high concentration of proteins in cerebrospinal fluid is due to a leakiness of the intercellular junctions between cerebral endothelial cells. However, the findings might be explained either by a low rate of production of cerebrospinal fluid in the youngest animals and/or by a pinocytotic transfer of proteins across the blood-brain barrier in these animals.8. In rats concentration gradients for ions are established at an age (new-borns) with a low or absent bulk formation of cerebrospinal fluid and at an age where the capillaries are still not enveloped by astrocytic foot processes. These facts suggest that the active transport mechanisms for the ions must be located in the cerebral endothelial cells. PMID- 4141374 TI - Sequence of structural changes in cultures of Clostridium tetani grown on a solid medium. PMID- 4141375 TI - Ultrastructural changes in renal tubules of sheep following experimental infection with Leptospira interrogans serotype pomona. PMID- 4141376 TI - Plasma proteins of the pregnant and normal Rhesus monkey (Macaca mulatta). A two dimensional electrophoretic study. PMID- 4141377 TI - Banding identification of partial trisomy 15 and of 8/21 translocation. PMID- 4141378 TI - Four cases of 9p trisomy resulting from a balanced familial translocation (9:15) (q13;q11). Clinical picture and cytogenetic findings. PMID- 4141379 TI - [Receptors of--steroid hormones: Progestogen]. PMID- 4141380 TI - [Evaluation of alpha fetoprotein analysis by rivanol sedimentation method]. PMID- 4141381 TI - [Case of polyclonal gammopathy with lymphadenopathy]. PMID- 4141382 TI - [Papanicolaou's staining using celestine blue (a substitute for hematoxylin)]. PMID- 4141383 TI - [Staining of the cell nucleus by a new gallocyanin solution]. PMID- 4141384 TI - [Double staining of frozen sections mounted on the gelatin slide: application to the histological study of blood vessels]. PMID- 4141385 TI - [Changes of the weight of liver slices caused by formalin fixation]. PMID- 4141386 TI - [Evaluation of muscle ATPase staining]. PMID- 4141387 TI - [Immunological examination of malignant tumors. (A) Clinical significance of alpha fetoprotein]. PMID- 4141388 TI - [Evaluation beta-gamma bridging]. PMID- 4141389 TI - [Clinical significance of the analysis of serum alpha globulin subfractions]. PMID- 4141390 TI - [Evaluation of trypsin pretreatment in Giemsa's staining]. PMID- 4141391 TI - [Antigenic changes of glucagon labeled with chloramine-T]. PMID- 4141393 TI - [Nursing in surgery of newborn infants. 1]. PMID- 4141392 TI - Studies on the healing of experimental ulcer in the rat II: influence of anti inflammatory drugs on the healing of the acetic acid ulcer and the components in gastric tissue. PMID- 4141394 TI - [Contribution on the clinical problems of idiopathic panuveitis (author's transl)]. PMID- 4141396 TI - [On the occurrence and formation of human SNagg-type antigamma globulins with anti-Gm- and anti-INV-specificity (author's transl)]. PMID- 4141395 TI - [Editorial: Antigammaglobulins of human origin]. PMID- 4141397 TI - The interpretation of electrocardiograms in small animals. PMID- 4141398 TI - [Prevention and treatment of post-vaccinal complications]. PMID- 4141399 TI - [Fistulas in the areas of esophagus, stomach, and bile ducts (author's transl)]. PMID- 4141400 TI - [Therapy of acute liver insufficiency (author's transl)]. PMID- 4141401 TI - [Modern methods of learning in surgical training (author's transl)]. PMID- 4141402 TI - [Bleeding from ruptured esophageal varices (author's transl)]. PMID- 4141403 TI - [Bleeding from the upper intestinal tract in infancy and childhood (author's transl)]. PMID- 4141404 TI - [Round-table discussion on the subject of gastrointestinal hemorrhages]. PMID- 4141405 TI - [Surgical indications--changes and developments, considered by a medical historian]. PMID- 4141406 TI - [Strauma maligna (author's transl)]. PMID- 4141407 TI - Nucleic acids attached to solid matrices. PMID- 4141408 TI - Angiotensin and catecholamines of the central nervous system. PMID- 4141409 TI - [Absorption of phosphate ion by eel intestine (anguilla anguilla L.). Comparison of two methods of studying in vitro transport at the muscosal level]. PMID- 4141410 TI - Effects of fasting on intermediate hepatic metabolism of the rat. PMID- 4141411 TI - [Nutrition of a lepidopteran caterpillar Plodia interpunctella Hubner (Lepidoptera, Pyralidae) on a chemically defined medium]. PMID- 4141412 TI - Protein nutrition of Tenbrio molitor L. XVII. Improved amino acid mixture and interaction with dietary carbohydrate. PMID- 4141413 TI - Vitamin B 2(riboflavin)-sparing activity of ascorbic acid in the larval nutrition of Oryzaephilus mercator Fauvel (Coleoptera). PMID- 4141414 TI - Metabolic kinetics of the anti-ketotic compound 1,2-propanediol in the rumen. PMID- 4141415 TI - [Intra-individual variability in the circadian rhythm of creatine excretion and urinary electrolytes]. PMID- 4141416 TI - Conditioning of depressor responses evoked by stimulation of aortic nerve in the rabbit. PMID- 4141417 TI - [Cardiovascular reactions released by the introduction of bradykinin in the sub arachnoid spaces in the anesthetized cat]. PMID- 4141418 TI - [Resistance of endogenous intraluminal phospholipids to pancreatic hydrolysis in intact rats]. PMID- 4141419 TI - Contralateral potentials in the suprasylvian gyrus evoked by pulvinar stimulation. PMID- 4141420 TI - Metabolic effects following a medium chain triglycerides load in dogs. V. Influence of the perfusion rate. PMID- 4141421 TI - [Ion tolerance in larvae of Salamandra salamandra L. (Amphibia, Urodele), immersed in distilled water]. PMID- 4141422 TI - Immunoaffinity chromatography of proteins. PMID- 4141423 TI - Bovine thyroid gangliosides: distribution pattern after differential pelleting. PMID- 4141424 TI - [Proceedings: Influence of beta-adrenergic receptor blockade on the hyperlactacidemia of exercise in hypoxia]. PMID- 4141425 TI - Proceedings: Ammonia and amino acids in the brain of the rat with chronic hepatic failure. PMID- 4141426 TI - [Proceedings: Influence of tryptophan on the hypotensive effect of arachidonic acid]. PMID- 4141427 TI - [Proceedings: Evolution of the rate of motor conduction and of distal latency of the internal popliteal sciatic nerve during exhausting muscular exercise]. PMID- 4141428 TI - Proceedings: Intra- and extracranial blood flow during sympathetic nerve stimulation. PMID- 4141429 TI - [Proceedings: Influence of pH on the activity of the microsomal calcium pump of smooth intestinal mucle]. PMID- 4141430 TI - Proceedings: Influence of changes in the acid-base balance on cerebral blood flow after an actue hypertensive insult. PMID- 4141431 TI - Cone and rod ERP in the human eye. PMID- 4141432 TI - Proceedings: Bioluminescence of a bathypelagic fish, Argyropelecus hemigymnus Cocco. PMID- 4141433 TI - Proceedings: Osmolality and myocardial function. PMID- 4141434 TI - [Proceedings: Alveolar argon plateau following a respiratory embolism formed by the tracer]. PMID- 4141435 TI - [Proceedings: Maximally effective muscular exercise in water at different temperatures]. PMID- 4141436 TI - [Proceedings: The RNA of oncogenic RNA viruses]. PMID- 4141437 TI - Proceedings: Structure and interactions of ribosomal ribonucleic acids of Escherichia coli and Proteus vulgaris. PMID- 4141438 TI - [Proceedings: Reactive sites of Escherichia coli methional tRNA synthetase]. PMID- 4141439 TI - Proceedings: Information content of an RNA genome. PMID- 4141440 TI - Proceedings: Previously unrecognized interactions among synthetic homopolynucleotides and their complexes revealed by interferon induction studies. PMID- 4141441 TI - Proceedings: Methylation of yeast aspartic-tRNA by enzymes from cytoplasm, chloroplasts and mictochondria of Phaseolus vulgaris. PMID- 4141442 TI - [Proceedings: Small molecular weight RNA from a murine oncornavius: 85 RNA from murine sarcoma virus (MSV-M-MLV)]. PMID- 4141443 TI - [Proceedings: Fixation of ethidium bromide to rRNA and to ribosomes of Saccharomyces cerevisiae]. PMID- 4141444 TI - Proceedings: Improved synthetic templates for the RNA-instructed RNA polymerase of bacteriophage Q beta. PMID- 4141445 TI - [Proceedings: Evidence for two serine tRNAs specific for phage T5]. PMID- 4141446 TI - Proceedings: Effect of polyamines on aminoacylation of tRNA from Phasaeolus vulgaris. PMID- 4141447 TI - [Proceedings: What is the conformation of single strand poly(A)?]. PMID- 4141448 TI - [Proceedings: Predictions on the intramolecular hydrogen bonding of nucleosides]. PMID- 4141449 TI - Proceedings: Isolation of acidic coat mutants of the RNA bacteriophage MS2 by use of polyacrylamide gel electrophoresis. PMID- 4141450 TI - [Proceedings: Synthesis of nuclear heterodisperse RNA at the beginning of maize germination]. PMID- 4141451 TI - Proceedings: Influence of pressure on the relaxation kinetics of the binding of ethidium bromide to yeast tRNA. PMID- 4141452 TI - Proceedings: Isolation and translation of a 33 s mRNA coding for a beef heavy chain thyroglobulin. PMID- 4141453 TI - Proceedings: Structure and function studies on ferritin. PMID- 4141454 TI - [Proceedings: Copper proteins]. PMID- 4141455 TI - Proceedings: Inhibition by Cd2+ of the endogenous respiration of Endomycopsis lipolytica. PMID- 4141456 TI - Proceedings: Activation of the inactive precursor of collagenase by kallikrein and plasmin. PMID- 4141457 TI - Proceedings: Sodium dodecyl sulphate electrophoresis on polyacrylamide gel of functional tryptic fragments of crystalline beta-haemocyanin of Helix pomatia. PMID- 4141458 TI - [Proceedings: Metalloenzyme-substrate complexes]. PMID- 4141459 TI - [Proceedings: Action of cyanogen bromide on human lactotransferrin]. PMID- 4141460 TI - [Proceedings: Absorption spectra of cardiac cytochromes in situ]. PMID- 4141461 TI - [Proceedings: Structure of glycan moieties of sero- and lactortransferrins]. PMID- 4141462 TI - Proceedings: Influence of pressure on the reduction of horse heart ferricytochrome c with potassium ferrocyanide. PMID- 4141463 TI - [Proceedings: Conformation of a bacterial ferredoxin]. PMID- 4141464 TI - Proceedings: The effect of monoglyceride feeding on serum lipoproteins in the absorptive state in man. PMID- 4141465 TI - Proceedings: Threshold-dependent phenomena in photomorphogenic processes. PMID- 4141466 TI - Proceedings: A long-term effect of phytochrome on the induction of chlorophyll synthesis. PMID- 4141467 TI - [Proceedings: Membrane proteins. Effect of erythrocyte charge on their sensitivity to silica]. PMID- 4141468 TI - [Proceedings: Catabolic repression by nitrogen of arginase synthesis in Saccharomyces cerevisiae]. PMID- 4141469 TI - [Proceedings: Isolation and characterization of peptides obtained by the action of cyanogen bromde on fragment B of diptheria toxin]. PMID- 4141470 TI - Proceedings: Stimulation of cellular transport by cyclic AMP in yeast. PMID- 4141471 TI - Proceedings: Endogenous lysophospholipids, phosphatide acyl hydrolase activity and fatty acids esterification in liver particles. PMID- 4141472 TI - [Proceedings: Tryptic cleavage of citraconylated of fragment b of diphtheria toxin]. PMID- 4141473 TI - Proceedings: Isolation of the A-protein from bacteriophage MS2 and sequence analysis of soluble trypitic peptides. PMID- 4141474 TI - Proceedings: Protein phophokinase associated with rabbit skeletal muscle sarcoplasmic vesicles. PMID- 4141475 TI - Proceedings: Functional significance of estrogen-induced protein in rat uterus. PMID- 4141476 TI - The cell coat in the neuropil of the chick spinal cord during development. PMID- 4141477 TI - [The lag phase of Saccharomyces cerevisiae growth following dehydration]. PMID- 4141479 TI - [The blind-end branch of the bifid ureter. Case report]. PMID- 4141478 TI - [Protein determination in suspensions of microbial cells using dichlorotriazine dyes]. PMID- 4141480 TI - [Pathological changes in the respiratory tract in Waldenstrom's macroglobulinemia. Example of 5 observations]. PMID- 4141481 TI - A new staining method for nucleoli. PMID- 4141482 TI - Fenfluramine-induced ultrastructural alterations in tissues of rats and guinea pigs. PMID- 4141483 TI - A histochemical study of the epidermal keratinization in the skin of a fresh water teleost Bagarius bagarius (Ham.) (Sisoridae, Pisces). PMID- 4141484 TI - [Problems and experiences in the topic psychological formation of the physician]. PMID- 4141485 TI - [1973 treatment of acute leukemias]. PMID- 4141486 TI - Rational management of thyroid auto-immune disease. PMID- 4141487 TI - The search for positive goitrogenic agents. PMID- 4141488 TI - Interrelations of the search for naturally-occurring goitrogens to the treatment of thyrotoxicosis. PMID- 4141490 TI - The current status of human pituitary cytophysiology. PMID- 4141491 TI - On the histogenesis of shark enamel. PMID- 4141489 TI - Purves symposium: 2. Pituitary morphology in relationship to function. General principles. PMID- 4141492 TI - [Polysaccharides in the spores of myxosporidians of the fam. Myxobolidae]. PMID- 4141493 TI - [Immunogenicity of Toxoplasma strains of differing virulence]. PMID- 4141494 TI - Sea-blue histiocytes in marrow in Batten-Spielmeyer-Vogt disease. PMID- 4141495 TI - Management of cataract and cataract surgery. PMID- 4141496 TI - Prevention of Rh immunization. Evaluation of Rh (D) antibody and elaboration of its mechanism of action by chromium-51 RBC clearing method. PMID- 4141497 TI - [Long-time results of intracavitary isotope therapy of malignant effusions]. PMID- 4141499 TI - Club foot; management and nursing responsibilities. PMID- 4141498 TI - Total hip replacement. PMID- 4141500 TI - [Alpha-fetoprotein (AFP) in normal and pathological states]. PMID- 4141501 TI - [Fetal antigens as indicators of human neoplasms]. PMID- 4141502 TI - [The effect of reagent concentration and pH on luminescence intensity during protein determination by the chemoluminescent method]. PMID- 4141503 TI - [Insulin immunogenicity]. PMID- 4141504 TI - [Some changes in lipid metabolism and the state of the vascular wall in rats with a prolonged course of alloxan diabetes]. PMID- 4141505 TI - [Effect of serotonin on the autoluminescing and adrenergic structures of the thymus gland]. PMID- 4141507 TI - The influence of a magnetic field on immunologic and enzymatic reactions carried out at a solid-liquid interface. PMID- 4141506 TI - [Certain problems of pathogenesis of diffuse non-toxic sporadic goiter]. PMID- 4141508 TI - [Postinfluenzal, chronic Guillain-Barre syndrome with oligoclonic gammopathy and generalized amyloidosis]. PMID- 4141509 TI - [Postinfluenzal, chronic Guillain-Barre syndrome with oligoclonic gammopathy and generalized amyloidosis]. PMID- 4141510 TI - Symbolic apperception and Integral Psychology. PMID- 4141511 TI - [Controlled study of the combination isoniazid-thioacetazone in the treatment of lung tuberculosis]. PMID- 4141512 TI - [Combination of P32 and testosterone in the treatment of pain due to osseous metastasis of prostate neoplasms]. PMID- 4141513 TI - Rheumatoid arthritis and the family. PMID- 4141514 TI - The facts about hair transplantation. PMID- 4141515 TI - [Instruments of prevention]. PMID- 4141516 TI - Cofactor of the "lupus anticoagulant". PMID- 4141517 TI - [Significance of brochoscopy for the checking of therapeutic results and observing the course of bronchial carcinoma treated with high voltage radiation]. PMID- 4141518 TI - [Early results of cytostatic treatment supplementing high-voltage radiotherapy of inoperable small-cell bronchial carcinoma]. PMID- 4141520 TI - [The effect of hypoxia on the histopathological picture of the incisor pulp in the rat]. PMID- 4141521 TI - [Progress in scientific oncology]. PMID- 4141519 TI - A radioimmunoassay of plasma estradiol-17beta with the use of polyethylene glycol to separate free and antibody-bound hormone. PMID- 4141522 TI - The continuing carrier problem. PMID- 4141523 TI - The human major histocompatibility system. PMID- 4141524 TI - [Effect of Ca ions on the sorption of an anionic phthalocyanine dye by single muscle fibers]. PMID- 4141525 TI - [2 glycogen fractions in rat liver cells (cytofluorometric study)]. PMID- 4141526 TI - [Tinctorial properties of glycerinated muscle models, contracted by ATP]. PMID- 4141528 TI - The effect of chemical structure and surface properties of synthetic polymers on the coagulation of blood. III. In vivo adsorption of proteins on polymer surfaces. PMID- 4141527 TI - Platelet adhesion to polymer surfaces. PMID- 4141529 TI - Renal preservation with Plasmanate-albumin perfusate: successful clinical use. PMID- 4141530 TI - [Pathologico-morphological characteristics of the D-2 isolate of Marek's disease on various cell cultures of avian origin]. PMID- 4141531 TI - [Synchronization of the heat in heifers by the peroral administration of chlormadinone acetate (CAP)]. PMID- 4141532 TI - [Use of some cytochemical methods for differentiation of peripheral blood and bone marrow cells in healthy cattle and in cattle with leukosis]. PMID- 4141533 TI - [Cultivation of organ cultures prepared from the respiratory tract of calves]. PMID- 4141534 TI - Sheep scab: its diagnosis and biology. PMID- 4141535 TI - [The effect of chlororganic pesticides on the bodies of animals]. PMID- 4141536 TI - [Activity of the thyroid gland and the sexual function in cows]. PMID- 4141537 TI - [Study of the cellular composition of the conjunctiva in animals]. PMID- 4141538 TI - [The effect of experimental hyper- and hypothyrosis on rat serum ceruloplasmin concentration]. PMID- 4141539 TI - The medical assistant. Training. PMID- 4141540 TI - The medical assistant. Discussion on assurance of qulaity, competence and accountability. PMID- 4141541 TI - [Mucinous carcinoma of the eccrine sweat glands]. PMID- 4141542 TI - [Simple semi-thin section method enabling various routine staining]. PMID- 4141543 TI - An in situ study of the hypothalamic neurosecretory system of some teleostean fishes. PMID- 4141544 TI - [Results of interruption of ventricular tachycardias using RR-linked interval stimulation]. PMID- 4141545 TI - [Tissue-specific antigens of the surface of the lymphocytes]. PMID- 4141546 TI - [Cross-reacting antigens of microorganisms and of mammalian tissues and their role in immunopathology]. PMID- 4141547 TI - [Immunological and immunomorphological study of experimental atherosclerosis in rabbits]. PMID- 4141548 TI - [Long-term effects of the estrogen-gestagen combination preparation Ovosiston on glucose level in the insulin tolerance test]. PMID- 4141550 TI - [Mathematical models of the primary immunological reaction (a review)]. PMID- 4141549 TI - [Gastric motor activity in steppe and swamp tortoises]. PMID- 4141551 TI - [Class E immunoglobulins (reagins) (a review of the literature)]. PMID- 4141552 TI - [Synthesis of serum gamma-globulins under conditions of bodily saturation with them]. PMID- 4141554 TI - [The anticomplementarity of gamma-globulin preparations]. PMID- 4141553 TI - [Common antigenic determinants in human lung tissue and several microorganisms]. PMID- 4141555 TI - [Cyto-serologic indices of immunity and their correlation in animals immunized against plague]. PMID- 4141556 TI - [Insecticide and insecticide-raticide preparations obtained by fixing toxic agents on sorbents]. PMID- 4141557 TI - [On problems of Sudeck's dystrophy (author's transl)]. PMID- 4141558 TI - [Contraception with low dose chlormadinone acetate. Clinical and histological results]. PMID- 4141559 TI - [Classification, value and significance of spermatogenic cells in human ejaculum]. PMID- 4141560 TI - [Immunohematology]. PMID- 4141561 TI - Ph1-negative chronic myelocytic leukemia with a missing Y chromosome. PMID- 4141562 TI - The fibrinolytic enzyme system in acute and chronic liver injury. PMID- 4141563 TI - Investigations on plasma viscosity in patients with cirrhosis of the liver. PMID- 4141564 TI - Heparinoids - a new inhibitor of experimental liver necrosis in rats. PMID- 4141566 TI - Studies on the integument of cestodes. I. Histology and histochemistry of the integument of the adult cestode Taenia hydatigena. PMID- 4141565 TI - Whipple's disease: etiopathogenesis, treatment, diagnosis, and clinical course. Case report and review of the world literature. PMID- 4141567 TI - Some remarks on the PAS reaction in semithin sections of Epon-embedded tissues. PMID- 4141568 TI - [Cholesteroldigitonide in the atherosclerotic aorta: Ultrastructural findings after fixation with a digitonin content aldehyde solution (author's transl)]. PMID- 4141569 TI - Lysosomal enzyme activities in the rectal gland of marine elasmobranchs. PMID- 4141570 TI - Nature of the protein and the mode of stabilization of the cuticular spines of liver-fluke Fasciola hepatica (L.). PMID- 4141571 TI - [Duodenal regulation of gastric secretion]. PMID- 4141572 TI - Leukocyte migration inhibition by brain tissue antigens in acute inflammatory diseases of the nervous system. PMID- 4141573 TI - Comparison between morphological changes and histamine release induced in rat mast cells by human allergic sera and specific allergen. PMID- 4141574 TI - Cupric sulfate-thionin method to demonstrate degeneration of neurofibrils in an Alzheimer case. PMID- 4141575 TI - Observations on a glycoprotein isolated from human aorta. PMID- 4141576 TI - Some aspects of the pathogenesis of prostatic hyperplasia. PMID- 4141578 TI - Structural correlates of the mechanism of action of indirect sympathomimetic amines. PMID- 4141577 TI - Benign hyperplasia of the human prostate exposed to steroid hormones in organ culture. PMID- 4141579 TI - Electron microscopy of bone marrow following the intravenous injection of colloidal gold. PMID- 4141580 TI - Interaction between skid row people and law enforcement and health professionals. PMID- 4141581 TI - Schistosoma mansoni: cercaria to schistosomule. PMID- 4141582 TI - Curriculum design for the generalist health care technician. PMID- 4141583 TI - Haemodynamic side-effects of pancuronium. PMID- 4141584 TI - Occupational hazards in anesthesia: survey of blood enzymes, morphology and serum proteins in anesthesia residents. PMID- 4141585 TI - [Giant hemo-lymph nodes in the man]. PMID- 4141586 TI - On the ultrastructure of the lymphoplasmocytes. PMID- 4141587 TI - Studies on the function of adrenodoxin and TPNH-cytochrome c reductase in the mitochondria and microsomes of adrenal cortex, utilizing immunochemical techniques. PMID- 4141589 TI - [Karyotype of a male atele (Ateles paniscus)]. PMID- 4141588 TI - [The mechanism of chromosome segmentation induced by BUDR (5-bromodeoxyuridine)]. PMID- 4141590 TI - A peculiar t(21 ; 14) translocation, associated with a pericentric inversion of the Y chromosome in a mongol boy. PMID- 4141591 TI - Presumably balanced translocations involving the same band of chromosome No. 4 found in two mentally retarded, dysmorphic individuals. PMID- 4141592 TI - [Hypotheses concerning the course of constant regions (Cgamma) in human IgG]. PMID- 4141593 TI - [A study of specificity of retinal antigens with the macrophage migration inhibition test (author's transl)]. PMID- 4141594 TI - [The induction in rabbits of precipitating auto-antibodies against brain extracts (author's transl)]. PMID- 4141595 TI - [Immunological relationship between neurotoxin and heavy purified endotoxins extracted from "Shigella dysenteriae" (Shiga), smooth and rough forms (author's transl)]. PMID- 4141596 TI - [An immunochemical study of an immunofluorescent serum factor present in normal subjects and active against "T. pallidum" (author's transl)]. PMID- 4141597 TI - [Tetanus prophylaxis using purified hyper-immune sera II. Laboratory animal study of pepsin-digested horse antitoxin (author's transl)]. PMID- 4141599 TI - Criteria for preparing, evaluating, and standardizing iodinated globulins for radioimmunoassay procedures. AB - Procedures were examined for labeling immune globulins with radioactive iodine using chloramine-T as the oxidizing agent. The chloramine-T method was critically evaluated to establish the optimal conditions for preparing iodinated globulins with high specific radioactivities without impairing their immunospecificities for use in in vitro radioimmunoassays. The results showed that the use of 100 mug of chloramine-T per ml, 500 to 1,000 muCi of Na (125)I per mg of protein, and a 10-min oxidation reaction time produced globulins of both high specific radioactivities and immunospecificities. Criteria were established for evaluating and determining optimal concentrations of iodine-labeled globulin for use in radioimmunoassays. The results of this investigation indicated that the amount of labeled indicator globulin used in radioimmunoassays should be based upon protein concentration rather than radioactivity. PMID- 4141598 TI - In vitro system for production of mouse mammary tumor virus. AB - An in vitro system for production, purification, and concentration of mouse mammary tumor virus is described. Monolayer cultures of C(3)H mouse mammary tumor cells propagated at 34 C in roller bottles in the presence of dexamethasone, a glucocorticoid hormone, release B-type particles which possess ribonucleic acid and a ribonucleic acid-dependent deoxyribonucleic acid polymerase. One thousandfold concentration by ultracentrifugation with subsequent gradient fractionation yielded > 7 x 10(10) particles per ml in the 1.16- to 1.18-g/ml region. Mouse mammary tumor virus produced in this system was free of detectable C-type virus. PMID- 4141600 TI - The techniques of surgery possible in incurable obstructive carcinoma of the corpus ventriculi. PMID- 4141601 TI - Familial cold urticaria. Clinical findings. PMID- 4141603 TI - Lupus erythematosus-like lesions in newborn infants. PMID- 4141602 TI - Immunosuppressive and cytotoxic drugs in dermatology. PMID- 4141604 TI - Citrate lyase from Rhodopseudomonas gelatinosa: purification, electron microscopy and subunit structure. PMID- 4141605 TI - [Bleomycin-Co 57 in the diagnosis of tumors of the respiratory]. PMID- 4141606 TI - Virions released from the surface of leukovirus-producing cells. PMID- 4141607 TI - [Quantitative determination of arginine in the nucleus of squamous epithelium of the human cervix uteri (author's transl)]. PMID- 4141608 TI - [Catechin derivatives from tormentilla roots]. PMID- 4141609 TI - [Bis-3-chromonyl-methanes from bis(4-hydroxy-3-coumarinyl)-methanes]. PMID- 4141610 TI - [The colour reaction of derivatives of hydrobenzoic acids under the condition of Vitalimorin]. PMID- 4141611 TI - [A method of selective silver impregnation of degenerating nerve fibers and their endings using pentavalent vanadium compounds]. PMID- 4141612 TI - [Leukoplakia and cancer of the vulva]. PMID- 4141613 TI - [Diagnosis of cancer in hyperplastic nodes of the prostate]. PMID- 4141614 TI - [Method of preparing and staining semithin sections]. PMID- 4141615 TI - [Ultrastructure of the prostatic epithelium in nodular hyperplasia and cancer]. PMID- 4141616 TI - [On the method of staining semithin sections with toluidine blue]. PMID- 4141617 TI - [Comparative morphometric analysis of changes in the glandular apparatus of the pyloro-antral division of the stomach in ulcer disease and cancer]. PMID- 4141618 TI - [Morphometric and pathohistological characteristics of myocardial infarct]. PMID- 4141619 TI - The pacemaker patient and his management. PMID- 4141620 TI - The roles of radiotherapy and cytotoxic drugs in the management of carcinoma of the esophagus. PMID- 4141621 TI - The pharmacological mediation of the acute inflammatory response: a brief review. PMID- 4141623 TI - Peptides from myelin basic protein as substrates for adenosine 3', 5'-cyclic monophosphate-dependent protein kinases. PMID- 4141622 TI - Metabolic studies on myelin. Evidence for a precursor role of a myelin subfraction. AB - Myelin prepared from brain tissue of the developing rat (15 days post partum) can be separated into several subfractions. These are (1) ;myelin-like' and ;purified myelin', by the technique of Davison and co-workers (Agrawal et al., 1970b) and (2) ;membrane fraction,' ;light myelin' and ;heavy myelin' by the discontinuous sucrose-gradient procedure described in the present paper. ;Myelin-like' and ;membrane-fraction' subfractions appear to be similar in chemical properties, but different in detailed morphology by electron microscopy. Both fractions are related to myelin, on the basis of demonstrable myelin basic protein by polyacrylamide-gel electrophoresis in sodium dodecyl sulphate and the presence of a myelin-marker enzyme, 2':3'-cyclic nucleotide 3'-phosphohydrolase. These two fractions have a low lipid content (17% for ;myelin-like' and 40% for ;membrane fraction' subfractions) compared with myelin (67-72%). No cerebroside was detected in these two fractions, whereas cerebrosides are a major component of myelin itself. The administration of [2,3-(3)H]tryptophan to young rats results in more rapid incorporation into proteins of the ;myelin-like' and ;membrane fraction' subfractions when compared with incorporation into myelin. Data are presented which are consistent with a precursor-product relationship for conversion of ;myelin-like' and ;membrane-fraction' subfractions into myelin. PMID- 4141624 TI - Anti-arrhythmic action of dilazep. Action on experimental arrhythmias induced by g-strophanthin (ouabain), epinephrine and aconitine. PMID- 4141625 TI - Adult acute leukaemia. AB - Seventy-eight adult patients with acute leukaemia were classified cytologically into 3 categories: acute lymphoblastic leukaemia (ALL), acute myelogenous leukaemia (AML) or acute undifferentiated leukaemia (AUL). The periodic acid Schiff stain was of little value in differentiating the 3 groups. The treatment response in each group was different: 94% of patients with ALL (16/17) achieved complete remission with prednisone, vincristine and other drugs in standard use in childhood ALL; 59% of patients with AML (27/46) achieved complete remission with cytosine arabinoside and daunorubicin (22 patients), or 6-thioguanine and cyclophosphamide (2 patients), 6-thioguanine, cyclophosphamide and Adriamycin (1 patient), and cytosine and Adriamycin (1 patient); only 2 out of 14 patients (14%) with acute undifferentiated leukaemia achieved complete remission using cytosine and daunorubicin after an initial trial of prednisone and vincristine had failed. Prednisone and vincristine would seem to be of no value in acute undifferentiated leukaemia. It would seem also that no benefit is obtained by classifying all patients with acute leukaemia over 20 years of age as "adult acute leukaemia" and treating them with the same polypharmaceutical regimen. The problems posed by each disease are different and such a policy serves only to obscure them. PMID- 4141627 TI - Eelctron microscopic studies of xeroderma pigmentosum: unusual changes in the keratinocyte. PMID- 4141626 TI - Alpha-foetoprotein in rats with nephrotoxic serum nephritis. PMID- 4141628 TI - Hereditary hypotrichosis simplex of the scalp. Evidence for autosomal dominant inheritance. PMID- 4141629 TI - Metastatic mucus-secreting mammary carcinoma in the eyelid. Report of two cases. PMID- 4141630 TI - [Thermal degradation of alpha s and beta caseins of the cow. II. Modifications of physicochemical properties]. PMID- 4141631 TI - [Action of certain antimitotic and immunosuppressive drugs on the electrophoretic mobility of human lymphocytes. Comparison with their action on blood platelets and red cells]. PMID- 4141632 TI - Current concepts on the ultrastructural pathogenesis of macular and lattice corneal dystrophies. AB - Some thoughts on the ultrastructural genesis of the lesions in macular and lattice corneal dystrophy are reviewed. These two genetically determined diseases of the cornea are symbolized by two chemical complexes, namely glycosaminoglycans and amyloid; they raise many questions about the biologic behavior of the cornea and its constituent cells and matrix stroma. Though the lesions in these two diseases appear to be localized to the cornea, the possibility of other tissues and organs being involved cannot be excluded at present, particularly when one takes into account that adequate postmortem studies have not yet been performed on patients with macular or lattice corneal dystrophy. To distinguish lattice corneal dystrophy from other disorders of the cornea which also contain amyloid, the term primary hereditary corneal amyloidosis is proposed. This terminology would seem appropriate in view of the fact that not all affected members of a family develop lesions with a lattice pattern. PMID- 4141633 TI - X-linked congenital panhypopituitarism. AB - Two half brothers with panhypopituitary dwarfism are reported who have the same mother and different, unrelated fathers. The subject of hereditary panhypopituitarism is reviewed briefly. It is concluded that there are at least two forms of hereditary panhypopituitary dwarfism, one of which may be X-linked. PMID- 4141635 TI - [Nature of the differential staining capacity of metaphasic chromosomes according to length]. PMID- 4141634 TI - Lipoid proteinosis. AB - Twenty-eight cases of lipoid proteinosis have been identified in a highly inbred White-Khoikhoi ("Hottentot") hybrid community living in Namaqualand, South Africa. The clinical manifestations of the disease are described, and a genetic analysis is presented. Genealogic studies have shown that the autosomal mutant gene for lipoid proteinosis was introduced into South Africa by a German settler and his sister in the mid-17th century. A great-grandson of that settler carried the gene to Namaqualand, where several generations of inbreeding have produced numerous affected homozygotes. PMID- 4141636 TI - An approach to recidivism. PMID- 4141637 TI - Studies on the metabolism of catecholamines in the central nervous system of the mouse. AB - 1 The distribution of the metabolites of noradrenaline, 1-(3,4 dihydroxyphenyl)ethane-1,2-diol (DOPEG) and 1-(4-hydroxy-3-methoxyphenyl)ethane 1,2-diol (MOPEG), in the brain of the mouse has been investigated.2 The rate of disappearance of the metabolites after inhibition of the enzyme monoamine oxidase has been used to estimate their turnover rates in the mouse hypothalamus. It was concluded that the turnover of DOPEG was much faster than that of MOPEG.3 When mice were treated with reserpine dissolved in 5% ascorbic acid solution there was an increase in the hypothalamic concentration of both MOPEG and DOPEG. However, similar increases in the concentrations of the two metabolites were seen when the animals were treated with 5% ascorbic acid solution alone.4 The administration of tropolone, an inhibitor of the enzyme catechol-O-methyl transferase, resulted in an increase in the concentration of DOPEG.5 Mice, exposed to a temperature of -15 degrees C showed increased hypothalamic concentrations of both DOPEG and MOPEG.6 The rates of formation in the mouse striatum of 3,4-dihydroxyphenylacetic acid (DOPAC) and 4-hydroxy-3-methoxyphenylacetic acid (HVA), acidic metabolites of dopamine, were compared with the turnover rate of dopamine, estimated from the rate at which this catecholamine disappears after treatment with alpha-methyl-p tyrosine. It was concluded that the estimate of dopamine turnover obtained by this method is likely to be too large because of the compensatory feedback mechanism which is thought to play a role in the metabolism of dopamine in the brain. PMID- 4141639 TI - Carcinoma of the penis and bleomycin chemotherapy in Uganda. PMID- 4141640 TI - [Carcinoma of the bile ducts]. PMID- 4141638 TI - Formation of a factor increasing vascular permeability during electrical stimulation of the saphenous nerve in rats. AB - 1 Increased vascular permeability following electric antidromic stimulation of the rat saphenous nerve was observed in the skin area supplied by the nerve, confirming previous results by other authors.2 The phenomenon was not affected by pretreatment of the rats with diphenhydramine, burimamide or their combination; atropine, methysergide, methysergide plus diphenhydramine, carboxypeptidase B, acetylsalicylic acid, indomethacin or methiazinic acid. It was partially reduced by previous injection of cellulose-sulphate, a kininogen-depleting agent.3 Perfusates from the subcutaneous tissue of the paw area supplied by the saphenous nerve contained permeability increasing activity as shown by intradermal tests in other rats. This activity was present in perfusates collected during nerve stimulation but not in those collected before stimulation. It was not destroyed by heating to 100 degrees C, or by alpha-chymotrypsin or trypsin.4 Bradykinin like activity may appear later in the perfusates, depending on the intensity of the stimuli.5 It is concluded that following electrical antidromic stimulation of the saphenous nerve a permeability increasing factor is released, possibly from nerves. It is dialysable and can be distinguished from acetylcholine, histamine, 5-hydroxytryptamine, plasma kinins, substance P, prostaglandins and high molecular weight proteins. The increased vascular permeability induced by this factor leads to plasma exudation and activation of the kinin system. PMID- 4141641 TI - [Alpha-1-fetal protein in patients with porphyria cutanea tarda]. PMID- 4141642 TI - [The activities of some hydrolases after administration of encephalitogenic protein (author's transl)]. PMID- 4141643 TI - [Hypothalamo-hypophyseal system of Symphodus (Teleostei, Labridae)]. PMID- 4141644 TI - Antigen-mediated macrophage adherence inhibition. PMID- 4141645 TI - Differentiation of lymphocytes in mouse bone marrow. II. Kinetics of maturation and renewal of antiglobulin-binding cells studied by double labeling. PMID- 4141646 TI - The role of immunoglobulin receptors on lymphocytes in production of MIF in guinea pigs. PMID- 4141647 TI - Differentiation of murine thoracic duct lymphocytes into T and B subpopulations by computer cell-scanning techniques. PMID- 4141648 TI - Role of lymphocyte surface determinants in lymph node homing. PMID- 4141649 TI - The human mixed-lymphocyte culture (MLC) interaction after in vivo allo immunization. II. HL-A specificity of early proliferative response. PMID- 4141650 TI - Tolerance induction to a thymus-dependent antigen in vitro: treatment of nonadherent cells with tolerogen biologically filtered in vitro. PMID- 4141651 TI - Effect of in ovo treatment with cyclophosphamide on lymphoid system in chicken. PMID- 4141652 TI - The influence of 2-mercaptoethanol (2-ME) treatment of IgG antibody on its ability to induce cytotoxicity in nonsensitized lymphocytes. PMID- 4141653 TI - [Antiglobulins in children. Serological properties of antiglobulins and some biological characteristics of their carriers]. PMID- 4141654 TI - Studies on encephalitogenic fragments of myelin protein. IV. Synthesis of glycine analogs of tryptophan-containing fragment. PMID- 4141655 TI - Studies on encephalitogenic fragments of myelin protein. III. Synthesis of H-Arg Phe-Ser-Trp-Gly-Ala-Glu-Gly-Asn-Arg-OH as an analog of encephalitogenic decapeptide. PMID- 4141657 TI - Antibodies to collagen in patients with emphysema. PMID- 4141656 TI - Diseases of the thyroid gland. PMID- 4141658 TI - T-lymphocyte differentiation in vitro in primary immunodeficiency diseases. PMID- 4141659 TI - Suppression of experimental allergic encephalomyelitis in Rhesus monkeys by a synthetic basic copolymer. PMID- 4141660 TI - Immunochemical studies of fragments of bovine nasal cartilage proteoglycan subunit. PMID- 4141661 TI - Disorders of the autonomic nervous system. Chapter 2. Relavant aspects of pharmacology. PMID- 4141662 TI - Predicting what antibodies an antigen will induce: the inadequacy of the determinant model. PMID- 4141663 TI - Human acute leukemia cells with membrane-bound immunoglobulin. PMID- 4141664 TI - Ultrahistochemical studies in the basal lamina of the visceral pleura of mice. PMID- 4141665 TI - Meningiomatoid proliferation of arachnoidal cells after focal brain injury. PMID- 4141666 TI - [Stimulation of experimentally inducdd tissue granulation by agglutinin obtained from Helix pomatia L. albumin glands (Anti-APH)--Part II (AUTHOR'S TRANSL)]. PMID- 4141667 TI - [Proceedings: T3 suppression test and TSH and prolactin reactions to TRH in patient with Basedow's disease under treatment with thyroid antagonists]. PMID- 4141668 TI - [Proceedings: Antigenic determinants of bovine peptide chains]. PMID- 4141669 TI - [Proceedings: 131 I uptake by the thyroid after termination of antithyroid agent treatment]. PMID- 4141670 TI - [Proceedings: Effect of inorganic iodine on serum thyroxine concentration in Basedow's disease--in patients during treatment with antithyroid agents]. PMID- 4141671 TI - [Proceedings: Effect of the volume of iodine uptake on recurrence of Basedow's disease: in patients with suppression of iodine uptake due to actions of antithyroid agents]. PMID- 4141672 TI - [Proceedings: Basedow's disease in pregnancy and parturition]. PMID- 4141673 TI - [Proceedings: Recovery rate in Basedow's disease treated with thyroid antagonists: frequency of development of suppression 1 year after the initiation of the treatment]. PMID- 4141674 TI - [Proceedings: Treatment of prostatic cancer with chlormadinone acetate. 1. The effect on testosterone dynamics]. PMID- 4141675 TI - [Proceedings: Immunological study of thyroid cancer: humoral immunity]. PMID- 4141676 TI - [Proceedings: Fetoplacental function test using the correlation ratio of serum HPL and alpha-fetoprotein]. PMID- 4141677 TI - [Proceedings: Effects of an antithyroid agent on the pituitary-thyroid system]. PMID- 4141678 TI - [Proceedings: T3 suppression test and TRH test for patients under treatment with anti-thyroid drugs for hyperthyroidism]. PMID- 4141679 TI - Localization of insulin on fat cell ghosts by ferritin labelled insulin antibodies. PMID- 4141680 TI - Identification and isolation of a foetoprotein in the chicken. PMID- 4141681 TI - Fluorescence cytochemical studies on oocyte growth in Chiton tuberculatum, with special emphasis on protein end-group methods. PMID- 4141682 TI - Innervation of adrenal cells in the lizards Lacerta dugesi and Lacerta pityusensis. PMID- 4141683 TI - Cytological detection of the c-25H deletion involving the albino (c) locus on chromosome 7 in the mouse. AB - A deletion of the albino (c) locus on mouse chromosome 7 has been demonstrated using Q- and G-banding methods in a mouse heterozygous for the radiation-induced lethal albino allele, c(25H). The deletion, which is thought to be 1-6 cM long, represents about 7.6% of the length of the metaphase chromosome. PMID- 4141684 TI - The histology and histochemistry of the cuticle of females of Enterobius vermicularis. PMID- 4141686 TI - Cytoarchitectonic structure of the subthalamic nucleus compared with adjacent structures in the rat. PMID- 4141685 TI - A metachromatic study of the distribution of acid mucopolysaccharides in the aortal wall of vertebrates. PMID- 4141687 TI - [Proceedings: Yolk sac tumor and alpha-fetoprotein]. PMID- 4141688 TI - Preparatory electroimmunodiffusion for making precipitins to selected native antigens. PMID- 4141689 TI - Secondary antibody response elicited in vitro with chicken gamma globulin1-4. PMID- 4141690 TI - Equine infectious anemia: detection of infections virus-antibody complexes in the serum. PMID- 4141691 TI - Isolation of pure human peripheral blood T-lymphocytes using nylon wool columns. PMID- 4141692 TI - Mast cell responses in mesenteric lymph nodes to infection of rats with the nematode, Nippostrongylus brasiliensis. PMID- 4141693 TI - Two myeloma globulins, IgG1-kappa and IgG1-lambda, from a single patient (Im). I. Purification and immunochemical characterization. PMID- 4141694 TI - Two myeloma globulins IgG1-kappa and IgG1-lambda, from a single patient (Im). II. Their common cellular origin as revealed by immunofluorescence studies. PMID- 4141695 TI - Immunoglobulins of the marsupial Setonix brachyurus (Quokka). Characterization of three major serum classes, IgG2, IgG1 and IgM. PMID- 4141696 TI - Separation of 'species' and major histocompatability antigen in the rat. PMID- 4141697 TI - Cytochemical studies in Indian childhood cirrhosis. PMID- 4141698 TI - [X-chromosome translocations. Examination based on treatment with BUDR and staining with acridine orange]. PMID- 4141699 TI - [Unilateral coxarthrosis with forme fruste of congenital analgia (indifference for pain) with normocalcemic hypercalciuria]. PMID- 4141700 TI - Non-fluorescent Y-chromosome. PMID- 4141701 TI - Electron microscopic examination of cartilage in the syndrome of exocrine pancreatic insufficiency, neutropenia, metaphyseal dysostosis and dwarfism. PMID- 4141703 TI - Vital staining of nerve fibres and endings. PMID- 4141702 TI - The thyrotropin releasing hormone test in idiopathic pituitary dwarfism. PMID- 4141704 TI - The cortico-nigral fibre tract. An experimental Fink-Heimer study in cats. PMID- 4141705 TI - Experimental alteration of the coronal sutural area: a histological and quantitative microscopic assessment. PMID- 4141706 TI - Biological significance and localization of antigenic determinant common to thiol proteases of plant origin. PMID- 4141708 TI - Quality control in cervical cytology. AB - From surveys conducted by the authors it is concluded that the best and most acceptable quality control methods in cytology are those from within the laboratory. Most of these have results which can be reported centrally. Where the overall control and codes of practice are high, there the results are the most reliable, as sources of error from whatever cause are quickly brought to light. These conclusions are illustrated by data from the five centres and correlated in the tables. PMID- 4141709 TI - Comparative cytogenetical and morphological studies in ovarian dysgenesis. AB - In 14 cases of the Turner syndrome and pure gonadal dysgenesis streak gonads were studied histologically. In cases where the 46,XX line was unimpaired the blood vessels of the gonad showed severe degeneration in at least 30 to 50%. These streak gonads usually contained some of the characteristic ovarian elements as well as the vascular lesions. In gonosomal monosomy, on the other hand, a similar intensive vascular degeneration could not be found and the gonad consisted of indeterminate connective tissue. These observations are strong indications of a close correlation between karyotype and the histology of the streak gonad, which may supply further information on the manner and timing of the development of the streak gonad. PMID- 4141707 TI - Anionic sites of human erythrocyte membranes. II. Antispectrin-induced transmembrane aggregation of the binding sites for positively charged colloidal particles. AB - The effects of affinity-purified antispectrin gamma-globulins on the topographic distribution of anionic residues on human erythrocytes membranes was investigated using collo ida iron hydroxide labeling of mounted, fixed, ghost membranes. Antispectrin gamma-globulins were sequestered inside ghosts by hemolysis and the ghosts were incubated for 30 min at 37 degrees C and then fixed with glutaraldehyde. The topographic distribution of colloidal iron hydroxide clusters on ghosts incubated with low (<0.05 mg/ml) or high (>5-10 mg/ml concentrations of sequestered antispectrin was dispersed, but the distribution at intermediate concentrations (0.1-5 mg/ml) was highly aggregated. The aggregation of colloidal iron hydroxide binding sites was time and temperature dependent and required the sequestering of cross-linking antibodies (antispectrin Fab could not substitute for gamma-globulin antibodies) inside the ghosts. Prior glutaraldehyde fixation or fixation at the time of hemolysis in antispectrin solutions prevented the antispectrin-induced colloidal iron site aggregation. The antispectrin reacted exclusively at the inner ghost membrane surface and the colloidal iron hydroxide bound to N-acetylneuraminic acid residues on the outer membrane surface which are overwhelming on the sialoglycoprotein glycophorin. These results were interpreted as evidence for a structural transmembrane linkage between the inner surface peripheral protein spectrin and the integral membrane component glycophorin. PMID- 4141710 TI - Tietze's disease. AB - The material from a case of Tietze's disease has been examined histologically. A review of the literature on the pathology of this lesion correlated with the findings from this case indicates that there is a pathological lesion in the costal cartilage in this disease. This consists of an increased vascularity and degenerative changes with patchy loss of ground substance leading to a fibrillar appearance. Cleft formation may occur with mucoid debris which may undergo calcification. Hypertrophic changes may be present at the periphery. The aetiology still remains obscure. PMID- 4141711 TI - Leukaemic reticuloendotheliosis: a morphological and immunological study of four cases. AB - Morphological and immunological studies of four cases of leukaemic reticuloendotheliosis are reported. The findings indicate that leukaemic reticuloendotheliosis is a monoclonal B cell neoplasm in which the leukaemic cell expresses either Kappa or lambda light chain and delta heavy chain determinants. The similarity between this disease and chronic lymphocytic leukaemia is discussed. PMID- 4141712 TI - Recent findings on the chemical structure and biological activity of bacterial lipopolysaccharides. PMID- 4141713 TI - Serological cross-reactions between Brucella abortus and Yersinia enterocolitica IX. PMID- 4141714 TI - Lethal effect of lipopolysaccharides (endotoxins) of various enterobacteria. PMID- 4141715 TI - Modified suprapubic prostatectomy (a report of 30 cases). PMID- 4141716 TI - An experimental study on the treatment of enlarged prostate. PMID- 4141717 TI - [Uptake of bleomycin by human brain tumors]. PMID- 4141719 TI - Some aspects of the development of the notochord in mouse embryos. PMID- 4141718 TI - Effect of oestradiol-17beta and progesterone on the metabolism of testosterone by human prostatic tissue. PMID- 4141720 TI - Cellular aspects of regeneration hormone influence in Nereis diversicolor. PMID- 4141721 TI - [Evidence for the role of an apical cap glycoprotein in amphibian regeneration: cytochemical and autoradiographic electron-microscopic studies (author's transl)]. PMID- 4141722 TI - The anoinic binding-sites at the cell surface after tissue dissociation and during the early phases of cell reaggregation. PMID- 4141723 TI - New concepts in the evaluation of the abnormal Papanicolaou smear. PMID- 4141724 TI - Methylation of myelin basic protein by enzymes from rat brain. PMID- 4141725 TI - The use of tutorial services and a self-study center. PMID- 4141726 TI - Pleomorphic adenoma of the vulva. PMID- 4141727 TI - The ultrastructure and time sequence of the early stages of paraquat lung in rats. PMID- 4141728 TI - Quantitation of histological changes in the glomeruli in renal biopsy specimens from children: total and differential glomerular cell counts. PMID- 4141729 TI - Congenital brain oedema of Hereford calves. PMID- 4141730 TI - Pigmented periductal cells (ochrocytes) in mammary dysplasias: their nature and significance. PMID- 4141731 TI - Studies on the pathogenesis of corneal arcus formation II. Immunofluorescent studies on lipid deposition in the eye of the lipid-fed rabbit. PMID- 4141733 TI - The effects of hexachlorophane on the nervous system of sheep. PMID- 4141732 TI - Fine structural alterations in the lungs of iprindole-treated rats. PMID- 4141734 TI - Involution of the post partum uterus of the ewe. PMID- 4141735 TI - Australian itch: diagnosis, control and economic importance. PMID- 4141737 TI - Letter: Capsid structure of bacteriophage lambda. PMID- 4141736 TI - Blood groups of the dwarf chimpanzee (Pan paniscus). PMID- 4141738 TI - Gamma-globulin allotypes of the Indonesians from Java-Madura, Indonesia. PMID- 4141739 TI - Genetic and biochemical studies on drug-resistant mutants in Mycobacterium smegmatis. PMID- 4141740 TI - Regular array in the cell wall of Lactobacillus fermenti as revealed by freeze etching and negative staining. PMID- 4141741 TI - Subtypes of hepatitis B surface antigen (HBsAg) in blood donors in Kumamoto, Japan. PMID- 4141742 TI - [Nursing experience with cesarean section with acupuncture anesthesia]. PMID- 4141744 TI - [Nursing in surgery of newborn infants. 3]. PMID- 4141743 TI - [A study on aldolase activity and isozyme pattern of the bladder tumor (author's transl)]. PMID- 4141745 TI - Activity stain for the detection of cyclic nucleotide phosphodiesterase in polyacrylamide gels. PMID- 4141746 TI - Malignant liver carcinoid: the place of surgery and chemotherapy. Review and case presentation. PMID- 4141747 TI - Letter: A study of lead concentrations in blood of children (and some adults) of Southern Tasmania. PMID- 4141748 TI - [Letter: The premature-beat index]. PMID- 4141749 TI - [Importance of the staining of reticular fibers in the diagnosis of liver diseases]. PMID- 4141750 TI - Effects of interferon on hemoglobin synthesis and leukemia virus production in Friend cells. PMID- 4141751 TI - Elements of the secondary structure in the DNA, complementary to pigeon globin mRNA. PMID- 4141752 TI - [Psychosocial dwarfism-a case report (author's transl)]. PMID- 4141753 TI - [Is there a characteristic cerebrospinal fluid cell picture in multiple sclerosis? The significance of large pyronine-staining round cells in the cerebrospinal fluid]. PMID- 4141754 TI - An electron microscopic study of the scrapie mouse and rat: further observations on virus-like particles with ruthenium red and lanthanum nitrate as a possible trace and negative stain. PMID- 4141755 TI - A membrane-associated network of protein filaments in nerve cells. PMID- 4141756 TI - [Clinical, electroencephalographic and biochemical aspects of the late prolonged phase of subacute sclerosing panencephalitis]. PMID- 4141757 TI - Orthopedic nurse specialist (orthopedic surgeon,s nurse assistant). PMID- 4141758 TI - [Influence of chlormadinone acetate on body- and organ weight of newborn rabbits]. PMID- 4141759 TI - Study of experimental hypertensive vascular lesions by ruthenium red staining technique. PMID- 4141760 TI - [Immunoprophylaxis of neonatal hemolytic disease caused by Rh incompatibility. Analysis of a 5-year experience]. PMID- 4141761 TI - Twenty-two years' experience in the medical management of juvenile thyrotoxicosis. PMID- 4141762 TI - [Hemolytic congenital nonspherocytic anemia secondary to an erythrocyte glucose 6-phosphate dehydrogenase deficiency. Description of 2 new variants: Gd (-) Saint Louis (Paris) and Gd (-) Hayem]. PMID- 4141763 TI - [Blue histiocytes and Gaucher cells in the spleen and lymph nodes in chronic myelogenous leukemia (author's transl)]. PMID- 4141764 TI - [Star shaped fibrin deposits in the bone marrow. Their presence and immunologic significance in graft vs host reaction in a primary immune deficiency]. PMID- 4141765 TI - [Clinical and biochemical studies of a new case of Hb J Baltimore (alpha 2A beta2 16 Gly yields Asp) isolated in France (author's transl)]. PMID- 4141766 TI - [Frequency and distribution of hemoglobin Lepore. Application of a rapid diagnostic test (author's transl)]. PMID- 4141767 TI - St. Christopher's Hospice. PMID- 4141768 TI - [Study of insulin-I-131 metabolism in some endocrine diseases]. PMID- 4141769 TI - [Diagnosis of the subclinical stages of diffuse toxic goiter]. PMID- 4141770 TI - [Functional state of the thyroid gland in essential obesity]. PMID- 4141771 TI - [Ultrastructural characteristics of the epithelium and capillaries of the parathyroid gland]. PMID- 4141772 TI - Vocational training in general practice: The evaluation of training programmes. PMID- 4141773 TI - Rheumatoid arthritis and systemic lupus erythematosus (SLE). PMID- 4141774 TI - Combination chemotherapy for testicular tumours. PMID- 4141775 TI - Alpha-fetoprotein and teratomas of the testis. PMID- 4141776 TI - An audio-visual experience for nurses. PMID- 4141777 TI - [New results and problems in the cytodiagnosis of the sputum in bronchogenic carcinoma (analysis of the 2-year material: 1967 and 1968]. PMID- 4141778 TI - Autoimmunity and lymphoid malignancy in New Zealand black mice. PMID- 4141779 TI - Carcinofetal antigens. PMID- 4141780 TI - Epidemiological and biochemical studies in filariasis in four villages near Bombay. PMID- 4141781 TI - [Immunochemistry of yeast mannan (author's transl)]. PMID- 4141782 TI - [Wittgenstein's language-game concept in psychoanalysis]. PMID- 4141783 TI - [Psychoanalytic theory of language development]. PMID- 4141784 TI - [Effects of different feeding patterns on the activities of histidine and D.O.P.A. decarboxylases in rat stomach (author's transl)]. PMID- 4141785 TI - Studies on swinepox virus: fluorescence and light microscopy of infected cell cultures. PMID- 4141786 TI - Ultrastructural studies on the bovine mammary gland with particular reference to glycogen distribution. PMID- 4141787 TI - Higher frequency of a protein band in the cerebrospinal fluid from scrapie mice. PMID- 4141788 TI - [Research on the prolonged administration of some organochlorine pesticide substances (lindane, DDT) on laboratory white mice]. PMID- 4141789 TI - [Modification of the organic composition of teeth in experimental hypothyroidism]. PMID- 4141790 TI - [The effects of automobile exhaust on man]. PMID- 4141791 TI - The structure of peripheral root dentin in young human premolars. PMID- 4141792 TI - Age changes in juxtaodontoblastic capillaries of rat molars. PMID- 4141793 TI - Chromosome banding pattern in acute myeloid leukaemia. PMID- 4141794 TI - Classification of art into style periods; a factor-analytical approach. PMID- 4141795 TI - The lymphocyte membrane. PMID- 4141796 TI - Precursors of thymus lymphocytes. PMID- 4141797 TI - Tissue localization of lymphoid cells. PMID- 4141799 TI - Cell to cell interactions in the immune response. PMID- 4141798 TI - Immunologic activities of thymus cell subpopulations. PMID- 4141800 TI - New aspects of lymphocytes in immunity. Concluding comments. PMID- 4141801 TI - [Health interests and preferred health education media as evaluated by adults]. PMID- 4141802 TI - [Nursing care of patients following surgery for hip arthrosis: we must prevent postoperative complications]. PMID- 4141803 TI - Protein transport across the placenta. PMID- 4141804 TI - [Postgraduate correspondence courses]. PMID- 4141805 TI - [Blood proteins in sarcoidosis of the respiratory organs]. PMID- 4141806 TI - [Movies in the teaching of a course in the propedeutics of internal diseases]. PMID- 4141807 TI - Subtypes of hepatitis B antigen (HBAg) in Peru. PMID- 4141808 TI - Electrophoretic separation of X- and Y-chromosome-bearing sperm in human semen. PMID- 4141810 TI - Mineral oil granulomatosis of scrotum. PMID- 4141809 TI - [Immunochemical properties of a soluble immune complex from the blood serum of cancer patients]. PMID- 4141811 TI - [What prevents the eradication of psoroptosis in sheep?]. PMID- 4141812 TI - The ultrastructure of the interfollicular epidermis of the hairless (hr/hr) mouse. II. Plasma membrane modifications during keratinization. PMID- 4141813 TI - [The inhibiting effect of 6-azacytidine on reproduction of smallpox virus in tissue culture]. PMID- 4141814 TI - Anti-I (A + B): an autoantibody detecting an antigenic determinant of I and a common part to A and B. PMID- 4141815 TI - Further data on HBs antigen subtypes - geographical distribution. PMID- 4141816 TI - Agarose gel electrophoresis of the human red cell acid phosphatase. PMID- 4141817 TI - [Re-entry as the cause of ventricular tachycardias with prolonged QT or QU time]. PMID- 4141818 TI - [Function period of various fixed-frequency and various demand pacemaker models by Biotronic, Cordis and Devices]. PMID- 4141819 TI - [Severe decrease of antigenicity and immunogenicity of bovine insulin by splitting off amino acids B1, B2 and B3 with substantial preservation of biologic activity]. PMID- 4141820 TI - [Ankylosing spondylitis and the histocompatibility antigen HL-A 27]. PMID- 4141821 TI - [Morphological detection of membrane-associated fibrinogen-antigenic determinants on human blood cells]. PMID- 4141822 TI - [Biochemical differential of leukemic and normal cells]. PMID- 4141823 TI - [Reverse transcriptase activities in preleukemia]. PMID- 4141824 TI - [In-vitro effect of DNA polymerases]. PMID- 4141825 TI - [Reverse transcriptase activity in the plasma of three patients with breast carcinoma]. PMID- 4141826 TI - [Radioimmunologic Au/SH-antigen determination (HBAg) in the salivia during various liver diseases]. PMID- 4141827 TI - Immunopathology of glomerulonephritis. PMID- 4141828 TI - The contribution of the scanning electron microscope to studies on the influence of chemotherapeutics on NK/Ly ascites lymphoma. PMID- 4141829 TI - [Cellular exudation in patients with primary chronic polyarthritis in Rebuck's skin window experiments]. PMID- 4141830 TI - [Protein separation using polyacrylamide gel electrophoresis and demonstration of differences of the gamma-globulins in various diseases, rheumatism]. PMID- 4141831 TI - [X-ray presentation of the seminal vesicles in the diseases of the male adnexa]. PMID- 4141832 TI - [Anti-antibodies. I. Obtaining anti-antibodies and some conditions required for their formation]. PMID- 4141833 TI - [The effect of heterogenous gamma globulin on several humoral factors of natural bodily resistance]. PMID- 4141834 TI - [Cytostatic, serologic and antigenic properties of protein complexed with 6 mercaptopurine]. PMID- 4141835 TI - [Change in the morphological and biological properties of microorganisms exposed to toxic serums from leukemic patients]. PMID- 4141836 TI - [Nonspecific properties of gamma globulin preparations (literature review)]. PMID- 4141837 TI - [Multiplication dynamics as an index of intracellular activity of bacteria (using Mycobacterium tuberculosis as a mode)]. PMID- 4141838 TI - [Pathogenesis of the graft versus host reaction and similar conditions (literature review)]. PMID- 4141839 TI - [Development of molecular biology and some prospects in the search for antiviral substances]. PMID- 4141840 TI - [Experience in obtaining human immunoglobulins]. PMID- 4141841 TI - [Effect of gamma-globulin on body reactivity. IV. Study of the sensitizing activity of gamma-globulin preparations using the mast cell degranulation test]. PMID- 4141842 TI - [Immunology of homoreactants (literature review)]. PMID- 4141843 TI - [Incidence of viral hepatitis in Andizhan and assessment of the effectiveness of serveral preventive measures]. PMID- 4141844 TI - [Skin test indices with several bacterial allergens in patients with viral hepatitis]. PMID- 4141845 TI - [Prospects for use of the preparation diphos for medical insect control]. PMID- 4141846 TI - [The diagnostic value of determining serum fructose-1-phosphate aldolase and alanine aminotransferase activity in patients with infectious hepatitis in the foci]. PMID- 4141847 TI - Median cleft of the upper lip and jaw. PMID- 4141848 TI - Modification of Csapody's method of conjunctival sac reconstruction in complete obliteration of the cavity. PMID- 4141849 TI - Plasty of hypo- and aplastic breasts using adipodermal grafts. PMID- 4141850 TI - Peripheral nerve homografting. A preliminary report. PMID- 4141851 TI - On problems involved in the sterilization of transplantation material. PMID- 4141852 TI - Syndrome of arteriomesenterial duodenal compression in children with burns. PMID- 4141853 TI - Rapid technique for contrasting embryonic tissues in secondary palate development studies. PMID- 4141854 TI - Cephalometric study of families with clefts. PMID- 4141855 TI - In memoriam Assistant Professor Teobald Adamczak, M.D. PMID- 4141856 TI - Effects of artificial intraocular pressure elevation on the outflow facility and the ultrastructure of the chamber angle in the vervet monkey (Cercopithecus ethiops). PMID- 4141857 TI - Carbonic anhydrase histochemistry, a critical study of Hansson's cobalt-phosphate method. PMID- 4141858 TI - Afferent C units responding to mechanical, thermal and chemical stimuli in human non-glabrous skin. PMID- 4141859 TI - Histochemical characteristics of human mast cells. PMID- 4141860 TI - Accessory neurosecretory cell groups in the rat hypothalamus. PMID- 4141861 TI - Effect of cycloheximide on induced autophagy in epithelial cells of the seminal vesicle of mice. PMID- 4141862 TI - Antigenic profile of neuraminidases of influenza A viruses isolated in 1957-1973. PMID- 4141863 TI - [Problems of cell cooperation in the humoral immune reaction]. PMID- 4141864 TI - [Antigenic competition in the lower vertebrates]. PMID- 4141865 TI - [Demonstration of immunoglobulin determinants on human lymphocytes]. PMID- 4141866 TI - [Light and electron-microscopic demonstration of surface-bound immunoglobulins with peroxidase-marked anti-IgG in human cultured lymphocytes]. PMID- 4141867 TI - [Regulation of antibody affinity]. PMID- 4141868 TI - [The phylogenetic development of antibody affinity]. PMID- 4141870 TI - [The effect of hapten-immunosuppressive agent complexes on the immune reaction]. PMID- 4141869 TI - [Regulation mechanisms in atopic sesnitization]. PMID- 4141871 TI - [The effect of antigen-immunosuppressive agent complexes on various immune reactions in the guinea pig]. PMID- 4141872 TI - [Experimental studies on the immune regulation of macrophages]. PMID- 4141873 TI - [Regulation of glomerular gamma globulin deposits by cytostatic agents in NZB hybrids]. PMID- 4141874 TI - Richardson's modified Southgate's mucicarmine stain compared to Mayer's mucicarmine. PMID- 4141875 TI - Injury and repair of arterial tissue: histochemical alterations. PMID- 4141876 TI - Injury and repair in arterial tissue: contraction and blebbing of endothelial cells in atherogenesis and thrombogenesis and abnormal secretion of sex hormone in Takayasu's disease. PMID- 4141877 TI - [Study of the interaction of certain antibiotics with DNA using a DNA-cellulose chromatographic method]. PMID- 4141878 TI - [Congenital indifference to pain. Report of a case]. PMID- 4141879 TI - [Changes in the lymph nodes of the white rat under the action of fluoroplast-3 destruction products against a background of adrenal function disorders]. PMID- 4141880 TI - [Binucleolate, binucleate and "double" neurons in the central nervous system]. PMID- 4141881 TI - [Projections of zones AI and AIV of the cat auditory cortex onto the corpus geniculatum mediale]. PMID- 4141883 TI - [Histochemistry of the skeletal muscle serotonin under the action of impulse magnetic fields]. PMID- 4141882 TI - [Endothelium of the aorta of the chick embryo during the first week of development]. PMID- 4141884 TI - [Use of the pickvorse's method for detection of the blood vessels on total specimens]. PMID- 4141885 TI - [Mucopolysaccharides of the aging joint cartilage of man]. PMID- 4141886 TI - [Prospects for a study of autonomic nervous system ganglia]. PMID- 4141887 TI - [Method of detecting lipofuscin. What does Schmorl's reagent reveal?]. PMID- 4141888 TI - Humoral immunity in relatives of patients with active chronic hepatitis. PMID- 4141889 TI - [The significance of nuclear DNA-measurements in the diagnosis of prostatic carcinomas (author's transl)]. PMID- 4141890 TI - Nursing management of transurethral resection of the prostate. PMID- 4141891 TI - Antigenic structures of hen egg-white lysozyme. IV. Antigenicity of the second loop. PMID- 4141892 TI - Amino acid sequence of the N-terminal 139 residues of light chain derived from a homogeneous rabbit antibody. AB - The amino acid sequence of the N-terminal 139 residues of the L (light) chain derived from a homogeneous rabbit antibody (designated BS-1) to type III pneumococci was determined. A combination of methods involving tryptic cleavage restricted to the 2 arginine residues of the molecule and mild acid hydrolysis of a labile peptide bond between the V (variable) and C (constant) regions of the L chain (Fraser et al., 1972) allowed the isolation of two large peptides comprising the entire V region (residues 1-109); these peptides were suitable for automated Edman degradation. The complete sequence analysis of the V region was carried out with only 4mumol of L chain. This material was homogeneous, although minor variant sequences, if present at the 10% value, would not have been detected. The L chain contains 3 intrachain disulphide bridges, whose pairing was established by diagonal electrophoresis: there is one V-region bridge between positions 23 and 88 and one C-region bridge between positions 134 and 194; the third one connects V and C domains between positions 80 and 171. When compared with the basic sequence of human kappa chains, rabbit L chain BS-1 appears to be more similar to the V(KI) prototype sequence than to V(KII) or V(KIII) sequences, where V(KI), V(KII) and V(KIII) represent subgroups I, II and III respectively of V regions of kappa light chains. The V regions of rabbit heavy and light chains are homologous to each other. The presence of two clusters of 3 glycine residues in positions 94-96 and 99-101 respectively is remarkable. Residues 94-96 may be related to antibody complementarity whereas residues 99-101 function probably as a pivot permitting the combining region of the L chain to make optimal contact with the antigenic determinant (Wu & Kabat, 1970). PMID- 4141893 TI - Amino acid sequence of the smaller basic protein from rat brain myelin. AB - 1. The complete amino acid sequence of the smaller basic protein from rat brain myelin was determined. This protein differs from myelin basic proteins of other species in having a deletion of a polypeptide of 40 amino acid residues from the centre of the molecule. 2. A detailed comparison is made of the constant and variable regions in a group of myelin basic proteins from six species. 3. An arginine residue in the rat protein was found to be partially methylated. The ratio of methylated to unmethylated arginine at this position differed from that found for the human basic protein. 4. Three tryptic peptides were isolated in more than one form. The differences between the two forms of each peptide are discussed in relation to the electrophoretic heterogeneity of myelin basic proteins, which is known to occur at alkaline pH values. 5. Detailed evidence for the amino acid sequence of the protein has been deposited as Supplementary Publication SUP 50029 at the British Library (Lending Division) (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms given in Biochem. J. (1973) 131, 5. PMID- 4141894 TI - Determination of volatile fatty acids in plasma after ethanolic extraction. AB - 1. A new rapid micro-method for measuring plasma volatile fatty acids is described. The volatile fatty acids are extracted from plasma with ethanol in the presence of a known quantity of internal standard (sodium isobutyrate). After evaporation of the ethanolic solution of the sodium salts, the residue is dissolved in a dilute solution of orthophosphoric acid to permit analysis by g.l.c. 2. A technique of g.l.c. analysis is described which permits the separation of all the volatile fatty acids from the other plasma constituents at temperatures below 100 degrees C in 5 min. 3. Steam-distillation techniques are unsatisfactory when the acetic acid concentrations in the plasma are below 0.2mm. Heating of a number of plasma constituents in acid conditions gives rise to acetic acid. 4. The binding of volatile fatty acids to plasma proteins was studied; this binding is negligible for acetic acid, but increases with the length of the fatty acid carbon chain. 5. The limits of use of the method and the physiological implications are discussed. PMID- 4141895 TI - An allotypic specificity presumably of the a series in rabbit immunoglobulins, different from a1, a2, and a3. PMID- 4141896 TI - Lipophilic chelator inhibition of mitochondrial membrane-bound ATPase activity and prevention of inhibition by uncouplers. PMID- 4141897 TI - Purification of canine antithrombin III-heparin cofactor using affinity chromatography. PMID- 4141898 TI - Circular dichroism variations among specifically purified rabbit antibodies. PMID- 4141899 TI - In vitro synthesis of DNA complementary to polyadenylated histone messenger RNA. PMID- 4141900 TI - [The immunoperoxidase method. Application to the study of immunoglobulin producing cells in the bone marrow of patients with monoclonal gammopathies]. PMID- 4141901 TI - Willebrand factor and ristocetin. I. Mechanism of rustocetin-induced platelet aggregation. PMID- 4141902 TI - Interspecific cross-reactivity of deciduoma antiserum: interaction between mouse deciduoma and antiserum to rat deciduoma. PMID- 4141903 TI - Histochemical localization of neutral lipid and choline-containing phospholipid in the epididymides of neopuberal Holstein bulls. PMID- 4141904 TI - Fatty acid composition of tissues in Refsum's disease (herodopathia atactica polyneuritiformis). Estimation of total phytanic acid accumulation. PMID- 4141905 TI - Adenosine 3'-5' cyclic monophosphate and guanosine 3'-5' cyclic monophosphate: effect on anaphylactic histamine release by rat mast cells. PMID- 4141906 TI - Metachromasia and human skin fibroblast cultures. AB - The importance of emphasizing the hazards of applying metachromasia as an indication of a specific genetic defect, or as a sole guide for genetic counseling, is discussed. PMID- 4141907 TI - The use of white blood cell cultures in studying genetic metabolic diseases. AB - Studies of white blood cell cultures in genetic metabolic diseases, in addition to those already in the literature, are reported. PMID- 4141908 TI - Congenital indifference to pain. PMID- 4141909 TI - Refsum's disease (heredopathia atactica polyneuriformis). PMID- 4141910 TI - The metabolic basis of the Refsum syndrome. AB - Studies in patients with the Refsum syndrome show that accumulation of phytanic acid stems from a metabolic error in the pathway for its oxidative degradation. The major degradative pathway involves an initial alpha oxidation followed by successive beta oxidation steps. The enzyme defect in patients with phytanic acid storage appears to be at the very first step, alphahydroxylation of phytanic acid. Heterozygous carriers have a partial fibroblasts in cell culture. On diets low in phytanic acid content, plasma phytanic acid levels fall and objective studies in patients suggest therapeutic benefit. PMID- 4141911 TI - Heredopathia atactica polyneuritiformis (Refsum's Disease): a second trial of dietary therapy in two patients. AB - Two sibs with heredopathia atactica polyneuritiformis (Refsum's Disease) each had a relapse after ceasing to follow a special diet. On being placed on a very restricted low phytol, low phytanic acid diet both had marked subjective improvement, and marked objective improvement both in physical findings and in quantitative tests of strength, dexterity, and motor nerve conduction velocities, concomitant with a fall in serum phytanic acid levels. No relapse occurred in 22 months on this diet. PMID- 4141912 TI - The effects of abate, an organophosphorous insecticide, on marsh fiddler crab populations. PMID- 4141913 TI - Seasonal changes in organochlorine compounds and mercury in common terns of Hamilton Harbour, Ontario. PMID- 4141915 TI - General discussion concerning the receptor organization. PMID- 4141914 TI - The effect of nerve stimulation on the axonal transport of noradrenaline and dopamine-beta-hydroxylase. AB - 1 A method for stimulating the lumbar sympathetic outflow from the spinal cord of the rat is described which does not require artificial respiration of the animal.2 In some, but not all experiments continuous stimulation at 2 Hz or intermittently at 10 Hz accelerated the rate at which noradrenaline and dopamine beta-hydroxylase accumulated central to a ligature on the sciatic nerve by approximately 40%.3 It is concluded that, although nervous activity is not necessary for axonal transport of transmitter granules in sympathetic neurones, intense nervous activity may accelerate the rate of granule transport. PMID- 4141916 TI - The stato-acoustic nuclear complex and the nucleus cerebelli of the frog. A golgi study. PMID- 4141917 TI - Projections of the intraotic ganglion to the medullary nuclei in the tegu lizard, Tupinambis nigropunctatus. PMID- 4141918 TI - The distribution of primary lagenar fibers within the vestibular nuclear complex of the pigeon. PMID- 4141919 TI - Cupular structure and its receptor relationship. PMID- 4141920 TI - Cochlear anatomy of the alligator lizard. PMID- 4141921 TI - [Comparative study of the morphology of rat and rabbit a alpha-macroglobulins in the presence of proteases]. PMID- 4141922 TI - [Cyto-immunologic study of early cell differentiation phenomena in the human fetal anterior pituitary gland]. PMID- 4141923 TI - [Histamine liberating capacity of 7 mono (O-beta-hydroxyethyl) rutoside in the rat]. PMID- 4141924 TI - The magnetocardiogram in cardiac disorders. PMID- 4141925 TI - Immunohistochemical demonstration of a CRF-associated neurophysin in the external zone of the rat median eminence. PMID- 4141926 TI - Changes in axonal transport in neurones of Asterias vulgaris and Asterias forbesei produced by colchicine and dimethyl sulfoxide. PMID- 4141927 TI - On club-shaped neurons establishing part of the deep moiety of layer VI in the human isocortex. A golgi and pigmentarchitectonic study. PMID- 4141928 TI - The mixed-leukocyte reaction in man: effect of pools of stimulating cells selected on the basis of crossreacting HL-A specificities. PMID- 4141929 TI - Short pulses of antigen induce in vitro an antibody response to haptenic determinants. PMID- 4141930 TI - Allotypes of anti-alloantibodies. PMID- 4141931 TI - Evidence for the presence in unimmunized mice of two populations of bone marrow derived B lymphocytes, defined by differences in adherence properties. PMID- 4141932 TI - Lymphocyte suppression associated with alpha globulin. Changes in cellular immunity. PMID- 4141933 TI - In vitro immune responses: effects of masking lymphocyte membrane components. PMID- 4141934 TI - Immunosuppressive activity of serum during the development of experimental allergic encephalomyelitis. PMID- 4141935 TI - In vitro and in vivo immune responses to homologous myelin basic protein in experimental allergic encephalomyelitis. PMID- 4141936 TI - In vitro suppression of immunoglobulin allotype synthesis by antibody specific for heavy chain determinants. PMID- 4141937 TI - The effect of Freund's complete adjuvant on the specificity of an immune response, and its relationship to antigenic competition. PMID- 4141938 TI - Interference with tolerance induction in mice by poly A:U. PMID- 4141939 TI - Specificity of antibody formation after intravitreal immunization with bovine gamma globulin and ovalbumin. II. Nonspecific enhancement of the secondary response. PMID- 4141940 TI - [Esophagoplasty in the treatment of cancers of the esophagus]. PMID- 4141941 TI - [Results of palliative operations of the gastrointestinal tract]. PMID- 4141942 TI - Immunological studies on liver diseases in the Mongolian People's Republic. AB - The sera of 445 persons, mainly patients with various liver diseases, were examined for alpha-fetoprotein (AFP) and hepatitis B antigens (HB Ag) and antibodies (HB Ab). The presence of AFP was detected in 9 sera by agar-gel precipitation and in 22 additional sera by the more sensitive aggregate haemagglutination technique. HB Ag proved to be present in 74 sera and HB Ab was present in 34 sera. Hepatitis B antigen was present more frequently (42%) in sera containing alpha-fetoprotein than in sera that did not contain it (14.7%). The food habits of the population investigated were also studied. PMID- 4141943 TI - Hepatitis B virus infection in northern India. Prevalence, subtypes, and seasonal variation. AB - Previous reports from India have been limited to the incidences of hepatitis B antigen (HB Ag) in health and disease. This paper reports on a study undertaken over the last two years to determine the incidence of hepatitis B virus infection, the serotypes prevalent among apparently healthy individuals and patients with liver diseases, and the seasonal incidence of sporadic acute hepatitis in this geographic area. The incidences of infection in health and disease show an endemic pattern. The Y subtype predominates among healthy carriers and patients with chronic liver diseases, whereas the D subtype predominates in patients with acute hepatitis. The similarity of subtypes of HB Ag among the majority of healthy carriers and patients with chronic liver diseases suggests that the majority of asymptomatic carriers (subclinically infected) would develop chronic liver disease. The proportion of HB Ag-positive cases of acute hepatitis was significantly higher during the two summer seasons than during the two winter seasons; this could be due to more frequent transmission of the virus by the faecal/urinary-oral route and its activation during the summer months, especially in areas with poor hygienic conditions. The urinary/faecal excretion of virus could thus maintain the natural transmission of the virus in such an environment. PMID- 4141944 TI - Comparison of strip and Ziehl-Neelsen methods for staining acid-fast bacteria. AB - The efficiency of the Ziehl-Neelsen method for staining acid-fast bacteria was compared with that of the strip-staining procedure in which one kind of impregnated strip is used to stain the bacteria and another kind for simultaneous decolorization and counter-staining of the smear. The methods were evaluated in 1 136 duplicate smears prepared from digested sputum and 307 pairs of direct smears. The efficiency of the strip method was comparable to that of the Ziehl Neelsen method with digested sputum; with direct smears, however, it generally depended on the quality of the smear. With thick, uneven smears, lower bacterial counts were obtained by strip staining. On the basis of this trial, the authors suggest improvement of the strip method. PMID- 4141945 TI - Sugar absorption by mouse small intestine. PMID- 4141946 TI - Genetic and biochemical studies of drug resistance in staphylococci. PMID- 4141947 TI - Biological properties of staphylococcal alpha- and beta-hemolysins. PMID- 4141948 TI - The staphylococcal enterotoxins: similarities. PMID- 4141949 TI - Immunological studies in nasal carriers of staphylococci. PMID- 4141950 TI - Antigen preparations from Staphylococcus aureus. PMID- 4141951 TI - Present status of the rheumatoid factor. PMID- 4141952 TI - Hyaline membrane disease in neonates treated with artificial ventilation: neurological and intellectual sequelae at two to five years of age. PMID- 4141953 TI - An assessment of methods used for measuring the recovery of mammalian cells from freezing and thawing. PMID- 4141954 TI - [Transitory algoporosis of the hip]. PMID- 4141955 TI - Cytological evidence for holocentric chromosomes of the silkworms, Bombyx mori and B. mandarina, (Bombycidae, Lepidoptera). PMID- 4141956 TI - Location, structure and behaviour of C-heterochromatin during meiosis in Dichroplus silveiraguidoi (Acrididae-Orthoptera). PMID- 4141957 TI - Mechanisms of chromosome banding. III. Similarity between G-bands of mitotic chromosomes and chromomeres of meiotic chromosomes. PMID- 4141958 TI - Chromosome banding and DNA replication studies on a cell line of Dipodomys merriami. PMID- 4141959 TI - Heterochromatin and disproportionate chromosome replication in Anatopynia dyari (Diptera: Chironomidae). PMID- 4141960 TI - The relationship between repetitive DNA and chromosomal bands in man. PMID- 4141961 TI - Distribution of mitomycin C-induced damage in human chromosomes with special reference to regions of repetitive DNA. PMID- 4141962 TI - Corticosteroids in terminal cancer. PMID- 4141963 TI - Chronic radium intoxication: clinical and autopsy findings in long-term New Jersey survivors. PMID- 4141964 TI - Oncorna-viral information in human melanoma. PMID- 4141965 TI - Nuclear DNA content and phytohormone requirements of normal, Crown gall and habituated tissues of Nicotiana tabacum var. White Burley. PMID- 4141967 TI - Semiconservative DNA duplication in human chromosomes treated with BUDR and stained with acridine orange. PMID- 4141966 TI - Is isolabeling a false image? PMID- 4141968 TI - Human chromosome structure as revealed by an immunoperoxidase staining procedure. PMID- 4141969 TI - Immunological selection of HL-A variants of cultured progeric fibroblasts and their identification by quinacrine fluorescence. PMID- 4141970 TI - Hodgkin's disease and the liver. PMID- 4141971 TI - Gastrointestinal tuberculosis. PMID- 4141972 TI - [Results after surgical treatment of Dupuytren's contracture]. PMID- 4141973 TI - [Participation of neutrophilic, eosinophilic and basophilic granulocytes in immunologic processes]. PMID- 4141974 TI - [Is myeloic metaplasia of the spleen caused by a disorder of immunobiologic functions?]. PMID- 4141975 TI - [Cytochemistry of leukocytes in childhood. I. Cytochemical reactions of leukocytes in infections--neutrophils--eosinophils--monocytes]. PMID- 4141976 TI - [Histiocytosis, a rare bone-marrow finding in an adult. Cytochemical and phase microscopic kinetic studies]. PMID- 4141977 TI - Immunocompetent and immunoneutral inflammatory mononuclear cells. PMID- 4141978 TI - Serum lysozyme (muramidase) as functional test of granulopoiesis in the course of cytostatic therapy. PMID- 4141980 TI - [Bone-marrow-finding documentation for electronic data processing]. PMID- 4141979 TI - [Cytologic reaction of bone marrow in adjuvant disease of the rat]. PMID- 4141981 TI - Investigations on the antigenic specificity of fibrinogen. PMID- 4141982 TI - Conclusions from the studies on hepatitis B antigen in blood donors. PMID- 4141983 TI - Comparative studies of the C cells in the thyroid glands of the domestic pig and cat. PMID- 4141984 TI - Effect of neuraminidase-treated and mitomycin C-treated polyoma tumour cells on the established tumour growth in CBA mice. I. An attempt at evaluation of polyoma tumour destruction using the distribution of lissamine green method. PMID- 4141985 TI - [Pharmacological study of prostate extract (III). Critric acid content and aconitase and isocitrate dehydrogenase activities in normal and hypertrophic prostates and the effect of prostate extracts]. PMID- 4141987 TI - Relationship between "desmosomes" and serrations of primary relief of cornifed epidermal cells. PMID- 4141986 TI - [Pharmacological study of prostate extracts. (IV). Prostatic acid phosphotases from several different species, and the effect of prostate extracts on these enzymes]. PMID- 4141988 TI - [Immunosuppression by antilymphocyte-gamma globulin. Incidence of circulating antibodies after administration of antilymphocyte-gamma globulin and their importance in the clinical medicine]. PMID- 4141989 TI - [Treatment of pain with Glifanan in chronic degenerative diseases of the locomotor system]. PMID- 4141990 TI - [Clinical aspects of enterogenic absorption disorders]. PMID- 4141991 TI - [Treatment of condylomata acuminata]. PMID- 4141992 TI - [Aspiration-cytology in breast tumors]. PMID- 4141993 TI - Analysis of reaction lag time to repeated visual inputs in the hyperthyroid patient by using correlation method. PMID- 4141994 TI - [Systemic sclerosis: (I) A review of 20 cases (author's transl)]. PMID- 4141995 TI - [Dermatomyositis: (I) A review of 7 cases (author's transl)]. PMID- 4141996 TI - [Serum alpha-fetoprotein positive gastric tumor]. PMID- 4141997 TI - Serum histaminopexy in allergic and non-allergic Indian subjects. PMID- 4141998 TI - Role of mono-amines in pentylene tetrazol induced seizure in mice. PMID- 4141999 TI - Banding patterns in chromosomes. PMID- 4142000 TI - Different stages of transformation of Rous virus-infected cells evidenced by methylene blue staining. PMID- 4142001 TI - Symbolism in a "protest psychosis". PMID- 4142002 TI - [Congenital sensory neuropathy]. PMID- 4142003 TI - Computerized chromosome identification by aid of the quinacrine mustard fluorescence technique. PMID- 4142004 TI - Identification of chromosome bivalents in human male meiosis by quinacrine mustard fluorescence analysis. PMID- 4142005 TI - Chromosome staining procedure for whole mounts of eggs and early embryos. PMID- 4142006 TI - The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability. PMID- 4142007 TI - Identification of different Robertsonian translocations in man by quinacrine mustard fluorescence analysis. PMID- 4142008 TI - Fluorescent pattern of apparently normal chromosomes in Burkitt lymphomas. PMID- 4142009 TI - Experiments with fluorescent chromosome staining in Burkitt tumors. PMID- 4142010 TI - Bacteriophage development in lysogenic Escherichia coli and mutations in fungi induced with analogs of tris(1-aziridinyl) phosphine oxide, TEPA. PMID- 4142011 TI - Chromosome-breaking capacity of TEPA and analogues in Vicia faba and Chinese hamster cells. PMID- 4142012 TI - Translocations causing non-fluorescent Y chromosomes in human XO/XY mosaics. PMID- 4142013 TI - The complexity of the fluorescent pattern of the human Y chromosome. PMID- 4142014 TI - Idiogram and fluorescence pattern of the chromosomes of the Indian muntjac. PMID- 4142015 TI - Are variations in length of Y chromosome due to structural changes? PMID- 4142016 TI - Karyotype XX/XY/XXY/XXXY in a Klinefelter patient. PMID- 4142017 TI - Repetitious DNA in mammalian chromosomes. PMID- 4142018 TI - Fluorescence study of interphase nuclei and double Y chromosomes. PMID- 4142019 TI - Fluorochromes and heterochromatin. A study of the chromosomes of Microtus agrestis L. PMID- 4142020 TI - The fluorescence pattern of the human karyotype. PMID- 4142021 TI - Fluorescent marker Chromosomes in malignant lymphomas. PMID- 4142022 TI - Bovine chromosomes identified by quinacrine mustard and fluorescence microscopy. PMID- 4142023 TI - Banding characteristics of paracentric marker constrictions in human chromosomes. PMID- 4142024 TI - A case of XX male.--Cytogenetic findings by autoradiography and fluorescence microscopy. PMID- 4142025 TI - Identification by fluorescence of the G chromosome lost in human meningomas. PMID- 4142026 TI - Identification of goat chromosomes by the quinacrine mustard fluorescence technique. PMID- 4142027 TI - Heterochromatin (C bands) in bovine chromosomes. PMID- 4142028 TI - Differential basophilia of adrenomedullary catecholamine storing granules induced by glutaraldehyde fixation. PMID- 4142029 TI - Effect of uncoupling agents and respiratory inhibitors on the growth of Streptococcus agalactiae. AB - 2,4-Dinitrophenol, dicoumarol, carbonylcyanide, m-chlorophenyl-hydrazone and pentachlorophenol all depressed aerobic molar growth yields of Streptococcus agalactiae to values equal to, or less than, those supported by substrate level phosphorylation. When the only source of energy was from substrate phosphorylation (anaerobic growth conditions), there was also a severe depression of the molar growth yield by the same four uncoupling agents. These results indicate that the effect of these agents is to uncouple both substrate and oxidative phosphorylation in S. agalactiae. Amytal inhibited glucose utilization, reduced the amount of O(2) used per mole of substrate and reduced the molar cell yield to that supported by substrate phosphorylation. Atebrin inhibited the respiration rate, but final O(2) consumed per mole of substrate was unchanged, and the respiration was coupled to biosynthesis. Rotenone had no effect on respiration, substrate utilization, or on molar growth yields. PMID- 4142030 TI - Incompatibility in Podospora anserina: comparative properties of the antagonistic cytoplasmic factors of a nonallelic system. AB - In the fungus Podospora anserina, the interaction between the nonallelic incompatible R and V genes has two consequences: a lytic reaction due to the synthesis of specific proteolytic enzymes, and a quenching in protein and ribonucleic acid synthesis. The incompatibility reaction when vegetative or sexual R and V cells fuse is asymmetric: it is induced only in the R protoplasm. The cessation in ribonucleic acid and protein synthesis was investigated in heterokaryotic strains carrying the antagonistic R and V genes and their "neutral" r and v alleles. Asymmetry between R and V genes lies in the fact that the strains homozygous for the R genes are the only strains that cannot grow. From these results it is postulated that the V-gene product is a diffusible cytoplasmic factor and that the R-gene product, which is nonautonomous, is a ribosomal component. PMID- 4142031 TI - Antigenic difference between polar montrichous and peritrichous flagella of Vibrio parahaemolyticus. AB - Polar monotrichous and peritrichous flagella of Vibrio parahaemolyticus were isolated and purified separately. On hydroxylapatite column chromatography, the flagellins of polar monotrichous flagella were eluted with a higher concentration of phosphate than those of peritrichous flagella. Gel diffusion tests showed an antigenic difference between the flagellins of polar monotrichous and peritrichous flagella. Electron microscope observations on cells stained with ferritin-conjugated antibodies demonstrated that polar monotrichous and peritrichous flagella reacted specifically with antimonotrichous flagellin and antiperitrichous flagellin antisera, respectively. PMID- 4142032 TI - Action of lysozyme on penicillin-induced filaments of Proteus vulgaris. AB - Penicillin-induced filaments of Proteus vulgaris P 18 had a seemingly unaltered cell envelope. Lysozyme, however, reduced the wall part of these filaments into a three-layered structure and caused transformation into spheroplasts. Although cross walls and membrane septa were absent in the filaments, most of the lysozyme induced spheroplasts remained attached to each other. PMID- 4142033 TI - Isolation and characterization of bacteria that grow on methane and organic compounds as sole sources of carbon and energy. AB - Bacteria capable of growth on methane and a variety of complex organic substrates as sole sources of carbon and energy have been isolated. Conditions used to rigorously establish the purity of the cultures are described. One facultative methylotroph has been studied in detail. This organism has peripherally arranged pairs of intracytoplasmic membranes characteristic of obligate methylotrophs. This isolate apparently utilizes the serine pathway of formaldehyde fixation. The location of methane oxidizers in a dimictic lake indicates that these organisms prefer less than saturating levels of dissolved oxygen. Laboratory experiments confirmed the preference of these organisms for atmospheres containing less oxygen than air. PMID- 4142034 TI - Characterization of specific antibodies to phenobarbital. PMID- 4142036 TI - The diphtheroid agent of ovine posthitis: its relationship to Corynebacterium renale. PMID- 4142035 TI - The possible viral aetiology of disseminated sclerosis. PMID- 4142037 TI - A biochemical study of experimental Johne's disease. I. Plasma protein leakage into the intestine of sheep. PMID- 4142038 TI - [Viability and enzyme activity of immobilized cells of steroid-transforming microorganisms]. PMID- 4142039 TI - Purification of anti-dinitrophenyl antibodies and their fractionation according to affinity. PMID- 4142040 TI - Alpha-lipoprotein heterogeneity in serum of mammals. PMID- 4142041 TI - Preparation of sensitive and stable erythrocytes by the carbodiimide method for the detection of primary and secondary IgM and IgG antibody. PMID- 4142042 TI - A need for critical evaluation of automatic microtitration machines. PMID- 4142043 TI - Ultrastructure of tracheal cilia during degeneration by sulphurous anhydride and exhaust gas. PMID- 4142044 TI - Differential cellular increase in cerebrospinal fluid after encephalography in mentally retarded patients. AB - The behaviour of the CSF cells during gas encephalography (GEG) with O(2), N(2)O, and halothane is poorly known in cerebral developmental disorders. One hundred and fifty CSF samples taken during pneumoencephalography from 75 mentally retarded patients were examined cytologically by the millipore technique with Papanicolaou staining. The results were processed automatically. An approximately 25-fold increase in CSF cells (P<0.001), mainly meningeal, reticulohistiocytic, and monocytic types, was found to occur. The cortical gas filling rate had a positive correlation (P<0.001) with the increase of number of CSF cells. There were no significant differences between the cellular changes in different cerebral disorders. Thus, though the irritant effect of GEG gives a rich cell yield, diagnostic atypical cells in developmental disorders of the central nervous system probably rarely exfoliate into the lumbar CSF. PMID- 4142045 TI - The effect of various disclosants on plaque accumulation in human subjects. PMID- 4142046 TI - Proceedings: A method for the quantitative estimation of gastric barrier mucus. PMID- 4142047 TI - Effects of Corynebacterium parvum and Freund's adjuvants on amphibian antibody responses. PMID- 4142048 TI - The effect of thyroid function on experimental cutaneous calcification in the rat. PMID- 4142049 TI - [Primary mega ureter in infants and small children (author's transl)]. PMID- 4142050 TI - [Cancer of the prostate detected in the adenomectomy specimen]. PMID- 4142051 TI - [Bladder irrigation with heparinized serum after prosptatectomy]. PMID- 4142052 TI - [Alpha-fetoprotein. 3. Evaluation of alpha-fetoprotein in gastric cancer and its liver metastasis]. PMID- 4142053 TI - A histochemical approach to the cholinergic innervation of endocrine-like cells in dog antro-pyloric mucosa. PMID- 4142054 TI - [Development and application of transrectal ultrasonotomography (author's transl)]. PMID- 4142055 TI - [Corticosteroids and tuberculosis (author's transl)]. PMID- 4142056 TI - [Nursing in pediatric surgery. 8. Information for personnel involved in pediatric surgery]. PMID- 4142057 TI - Electron microscopical studies on the renal arteriole in hypertensives and non hypertensives. II. Renal arteriole in non-hypertensives. PMID- 4142058 TI - [Vascular and tissue permeability in allergic diseases]. PMID- 4142059 TI - [Current possibilities in the treatment of prostatic adenoma]. PMID- 4142060 TI - Fire as a symbol and as a weapon of death. PMID- 4142061 TI - [Senile disease of the prostate in relation to preventive examination]. PMID- 4142062 TI - [Effect of oral and transcutaneous application of SP 54 on preformed thrombi in animal experiments]. PMID- 4142063 TI - Concentrations in virto of various enzymes in liver homogenates during the first few days of a period of starvation. PMID- 4142064 TI - Proceedings: On the conversion of tryptophan into 2-thiol-tryptophan, via thiolysis of the dinitrophenylsulfenyl derivative. PMID- 4142065 TI - Studies on the bacterial spore coat. 5. Effect of sodium dodecyl sulphate sonic treatment on the spore of Bacillus thiaminolyticus. PMID- 4142066 TI - [Differential diagnosis of toxoplasmosis and sarcocysts in the cardiac and skeletal muscles of cattle, sheep, and swine]. PMID- 4142067 TI - [Review of the 10 years work (1961-1970) of the Commission for Categorizing and Recording Cases of children with Disturbed Psychosomatic Development in the commune of Sombor]. PMID- 4142068 TI - [The Chediak-Higashi syndrome. Description of a case and recent etiopathogenetic acquisitions]. PMID- 4142069 TI - Protoplasmic incompatibility and female organ formation in Podospora anserina: Properties of mutations abolishing both processes. AB - A genetic block, effective only with the addition of mutations in two genes, suppresses both the incompatibility process in strain confrontation ("barrage") and the formation of female organs. Investigation on this block lead us to propose that it operates at the ribosomal level and prevents the translation of the messenger of a proteolytic enzyme, a postulated early protein in protoperithecia differenciation. PMID- 4142071 TI - Focussed microwave radiation: a technique to minimize post mortem changes of cyclic nucleotides, dopa and choline and to preserve brain morphology. PMID- 4142070 TI - Effects of compound 48/80 on mast cells, histamine, and cyclic AMP in isolated superior cervical ganglia. PMID- 4142072 TI - Uses and limitations of gammaglobulin therapy (literature review). PMID- 4142073 TI - [Measles--therapy in general practice. Short communication]. PMID- 4142074 TI - [Autistic syndromes in childhood. A contribution to the differential typology and pathogenesis(author's transl)]. PMID- 4142075 TI - [Rubeola--practical therapy]. PMID- 4142076 TI - Trypanosoma (Schizotrypanum) dionisii of pipistrellus pipistrellus (chiroptera): intra- and extracellular development in vitro. PMID- 4142078 TI - [Use of apizatron and histaglobin in the overall treatment of bronchial asthma in children]. PMID- 4142077 TI - Similitudes and differences in the reactivity of the liver cell chromatin to thioacetamide and hydrocortisone. Electron microscopic and cytochemical quantitative data concerning the chromatin condensation-dispersion cycle. AB - The administration of thioacetamide (TAA) and/or hydrocortisone to rats brought about dispersion of the heterochromatin in the liver cell, and concomitant stimulation of RNA synthesis in the chromatin. In contrast to other experimental situations in which dispersion of the chromatin persisted for at least 6 hours, after TAA injection dispersion was followed by rapid excess condensation. A hypothesis is suggested concerning the process of induction of malignant proliferation by TAA. PMID- 4142079 TI - [Some data on the specific functions of the female organism in women working with hexachlorocyclohexane]. PMID- 4142080 TI - [Serum alpha-fetoprotein (AFP) after primary liver cancer resection in adult value of its determination in the detection of recurrence]. PMID- 4142082 TI - [World distribution of tropical diseases]. PMID- 4142081 TI - [Letter: Protein alterations in human trichinosis]. PMID- 4142083 TI - The miracle of corneal transplant surgery. PMID- 4142084 TI - Prenatal diagnosis. PMID- 4142085 TI - [Effect of air pollution on the animal]. PMID- 4142086 TI - [Primary malignant hepatic neoplasms in children (author's transl)]. PMID- 4142087 TI - [Intra-arterial treatment of malignant neoplasms in children (author's transl)]. PMID- 4142088 TI - [Investigations on the Polish "human gammaglobulin" preparations (author's transl)]. PMID- 4142089 TI - [Clinical effectiveness of antireticular cytotoxic serum in a complex treatment of pulmonary tuberculosis]. PMID- 4142090 TI - [Effects of information slides on opinions about gingivitis in young men]. PMID- 4142091 TI - Role of nutrition in the drug-metabolizing enzyme system. PMID- 4142092 TI - [Blood protein electrophoresis: studies of the results obtained by automatic and semiautomatic photodensitometry]. PMID- 4142093 TI - Etiologic agents of immune-deposit disease. PMID- 4142094 TI - Autoimmunity in liver diseases. PMID- 4142095 TI - Human gamma-g subclasses. PMID- 4142096 TI - [Vital staining of lysosomes and other cell organelles of the rat with neutral red (author's transl)]. PMID- 4142097 TI - Ultrastructural localization of carbohydrate in the hymenium and subhymenium of Coprinus. Evidence for the function of the Golgi apparatus. PMID- 4142098 TI - [Primary liver cancer with and without cirrhosis: review of 50 cases]. PMID- 4142099 TI - [Extrasystoles of the bundle of His normalizing the complete left block through Wedensky's phenomenon]. PMID- 4142100 TI - Selective uptake of specifically purified antibodies to carcinoembryonic antigen of human adenocarcinoma. PMID- 4142101 TI - [Observations on the diagnostic character of nitroblue tetrazolium test]. PMID- 4142102 TI - [Histo-enzymological study of the experimental Arthus reaction in the lung]. PMID- 4142103 TI - [Histological comparison of healthy, pre-carious and carious dentin. Nosological theories which follow]. PMID- 4142104 TI - [Taste and salivary gland secretion disorders secondary to surgery for oto spongiosy. Diagnostic value of scintigraphy]. PMID- 4142106 TI - The formation of antibodies against hidden determinants of autologous IgG during immunization of rabbits with Staphylococcus aureus. PMID- 4142105 TI - Platelet stain preventing factor in serum or plasma--an early sign of leiomyosarcoma? PMID- 4142107 TI - The influence of epitope density on the immunological properties of hapten protein conjugates. III. Induction of hapten-specific tolerance by heavily and lightly hapten-substituted serum albumin. PMID- 4142109 TI - Florid keratoacanthomas in a kidney transplant recipient. Case report. PMID- 4142108 TI - Same idiotype of B-lymphocyte membrane IgD and IgM. Formal evidence for monoclonality of chronic lymphocytic leukemia cells. PMID- 4142110 TI - Rheumatoid arthritis and cancer arthritis. II. AB - A total of 394 patients with rheumatoid arthritis were followed-up over a 10-year period from 1963 to 1973, particularly with reference to the aetiological circumstances and in particular, cancer. Cancer was found as cancer arthritis in 50 cases (13 percent) at a stage where it was not possible to find focal cancer symptoms. No definite difference was found in the clinical course of the rheumatoid arthritis, no matter the varying aetiology, A series of statistically significant differences in the laboratory values for rheumatoid arthritis and cancer arthritis, respectively, are indicated and discussed. For that matter, the above observations are not original, in spite of what has been claimed, as Uncle Vanja in the play of the same name by Chekhov says: "They say that Turgenev got cancer as a result of his arthritis." PMID- 4142111 TI - [Improved method of automatic (Hema-Tek) staining of blood and bone marrow smears]. PMID- 4142112 TI - [Value of direct immunofluorescence method in the diagnosis of acute gonorrhea]. PMID- 4142113 TI - [Cardiac manifestations in hemochromatosis and their treatment by bloodletting]. PMID- 4142114 TI - Ades mosquito surveillance in the republic of Vietnam. PMID- 4142115 TI - Variability of heparin preparations in clinical use. PMID- 4142116 TI - Hazards of anticoagulant treatment: other drugs, other diseases. PMID- 4142117 TI - Measurements of size and weight of prostate by means of transrectal ultrasonotomography. PMID- 4142118 TI - Experimental infection with Mycoplasma pneumoniae in the young hamster: location of ferritin-labeled antibody binding to infective tissue. PMID- 4142119 TI - Fractionation of bulldog ant venom. PMID- 4142120 TI - Color differences in heated and Giemsa stained mouse chromosomes. PMID- 4142121 TI - Staining pollen nuclei with Snow's alcoholic hydrochloric acid-carmine. PMID- 4142122 TI - Rapid single-solution polychrome staining of semithin epoxy sections using polyethylene glycol 200 (PEG 200) as a stain solvent. PMID- 4142123 TI - A modification of the Glees silver impregnation for normal and degenerating nervous tissue. PMID- 4142124 TI - Embedding of myelinated nerve tissue in water-soluble resorcinol-formaldehyde resins for light and electron microscopy. PMID- 4142125 TI - Prevention of chemography in prestained epoxy autoradiographs by an intervening carbon film. PMID- 4142126 TI - Iron alizarin blue S stain for nuclei. PMID- 4142127 TI - Poststaining sections for electron microscopy. PMID- 4142128 TI - A rapid method to demonstrate muscle cross-striations with thionin. PMID- 4142129 TI - Thiosulfation aldehyde fuchsin (TAF) procedure for the staining of pancreatic B cells. PMID- 4142130 TI - Embedment of swimming cells in thin, removable epoxy films without centrifugation, encapsulation, or filtration. PMID- 4142131 TI - A method for retaining tissue sections on slides. PMID- 4142132 TI - Epon-embedded tissue stained with aldehyde-fuchsin for radioautography. PMID- 4142133 TI - A simplified resectioning technique. PMID- 4142134 TI - Simultaneous staining of the spindle apparatus and constitutive heterochromatin. PMID- 4142135 TI - Hematoxylin substitutes: gallein as a biological stain. PMID- 4142136 TI - Mordant blue 3: a readily available substitute for hematoxylin in the routine hematoxylin and eosin stain. PMID- 4142137 TI - Batch variations in commercial dyes employed for Romanowsky-type staining: a thin layer chromatographic study. PMID- 4142138 TI - Further considerations on a simple histological method for identification of osteoid matrix. PMID- 4142139 TI - Double embedding again. PMID- 4142140 TI - Glycol methacrylate in light microscopy: a routine method for embedding and sectioning animal tissues. PMID- 4142141 TI - Effect of sodium sulfite purity on color of Bodian silver staining of insect central nervous systems. PMID- 4142142 TI - Differentiation of type II alveolar cells--a new use for the Cason stain. PMID- 4142143 TI - Foley catheter in intracardiac perfusion. PMID- 4142144 TI - Immunogenicity of Entamoeba histolytica antigen fractions. PMID- 4142145 TI - Tolerance, enhancement and the regulation of interactions between T cells, B cells and macrophages. PMID- 4142147 TI - Bacteriology of tuberculosis. PMID- 4142146 TI - The relationship between humoral and cell-mediated immunity. PMID- 4142148 TI - Pulmonary tuberculosis: chemotherapy programmes and regimens of chemotherapy. PMID- 4142150 TI - [Air pollution and its implication to health]. PMID- 4142149 TI - [Adriamycin in combination and in combined treatment modalities (author's transl)]. PMID- 4142151 TI - [Effectiveness of a specific gamma-globulin in leptospirosis of swine]. PMID- 4142153 TI - [Erythrocyte changes in healthy dogs]. PMID- 4142152 TI - [Comparative determinations of Mycobacterium resistance using the vertical diffusion test and the proportion method (economical test)]. PMID- 4142155 TI - [Compartmentalized stain-contains supply for the floating staining technic of incisions]. PMID- 4142154 TI - [Analgesia in myocardial infarct]. PMID- 4142156 TI - [Pathology in Karlsruhe]. PMID- 4142157 TI - [From the cell picture of Rudolf Virchow to modern cytology]. PMID- 4142158 TI - [Applied cytology and their fundamentals (author's transl)]. PMID- 4142159 TI - [Cytology of the synovial fluid (report) (author's transl)]. PMID- 4142160 TI - [Exfoliative cytology of the oral mucosa (report) (author's transl)]. PMID- 4142161 TI - [The exfoliative cytology of the gastrointestinal tract (report) (author's transl)]. PMID- 4142162 TI - [The cytology of the urinary sediment as a contribution to the pathology of carcinoma of the urinary bladder (report) (author's transl)]. PMID- 4142163 TI - [Cytology of the cerebrospinal fluid (report) (author's transl)]. PMID- 4142164 TI - [Transrectal aspiration biopsy of prostatic tumours (report) (author's transl)]. PMID- 4142165 TI - [Puncture cytology of thyroid gland. Diagnosis of functional changes (report) (author's transl)]. PMID- 4142166 TI - [Aspiration cytology in the differential diagnostic of palpable lesions of the thyroid (report) (author's transl)]. PMID- 4142167 TI - [Aspiration cytology of the lung (report) (author's transl)]. PMID- 4142168 TI - [Cytologic diagnosis of mammary carcinoma from aspiration biopsy smears (report) (author's transl)]. PMID- 4142169 TI - [Modern trends in cytologic diagnosis (report) (author's transl)]. PMID- 4142170 TI - [Quality control in the cytodiagnostic laboratory (author's transl)]. PMID- 4142171 TI - [Diagnostic value of histology and cytology (author's transl)]. PMID- 4142172 TI - [Cytophotometric measurements of DNA and histone protein content of cells in pleura exsudates with malignant and inflammatory processes (author's transl)]. PMID- 4142173 TI - [Diagnostic value of impulse cytophotometric DNA histograms of malignant and non malignant effusions (author's transl)]. PMID- 4142174 TI - [Basic topics in karyology (report) (author's transl)]. PMID- 4142175 TI - [Characterisation of transitional cell tumors of the urinary bladder by cytophotometric investigations and by studies of the nuclear structure (author's transl)]. PMID- 4142176 TI - [Cytogenetic findings in ovarian tumors (author's transl)]. PMID- 4142177 TI - [Cytologic and histologic criteria as variables of an automatized diagnostic scheme (author's transl)]. PMID- 4142178 TI - [DNA-content of mitotic cells in dysplasia and carcinoma in situ of the uterine cervix (author's transl)]. PMID- 4142179 TI - [DNA-cytofotometry of dysplasia of cervix uteri (author's transl)]. PMID- 4142180 TI - [Interpretation of differencies in the DNA-values of exfoliated cells in gynecologic smears (author's transl)]. PMID- 4142181 TI - [Cytogenetic investigations in precancerosis of the cervix uteri (author's transl)]. PMID- 4142182 TI - [A new method of fine-structural study of beginning stromal invasion in early carcinoma of the uterine cervix (author's transl)]. PMID- 4142183 TI - [Cyto-histological investigation of abnormal portio and cervix uteri findings with regard to exogenous hormones (author's transl)]. PMID- 4142184 TI - [Morphometry of human liver biopsies--indicated in presymptomatic WILSON's didease (author's transl)]. PMID- 4142185 TI - [Fine-needle aspiration biopsy of the liver (author's transl)]. PMID- 4142186 TI - [Lysis of liver cells containing alcoholic hyalin by neutrophilic granulocytes- an electron-microscopic study (author's transl)]. PMID- 4142187 TI - [Studies of liver biopsies in thalassaemia major (author's transl)]. PMID- 4142188 TI - [Submicroscopic identification of the large pyroninophilic cells in cerebrospinal fluid of multiple sclerosis patients (author's transl)]. PMID- 4142189 TI - [Small and big rounded cells ("rundzellen") of the cerebrospinal fluid and lymphocytes of the peripheral blood. A comparative cytomorphological study (author's transl)]. PMID- 4142190 TI - [Different phagocytic activity of cells of the cerebrospinal fluid after lumbar puncture (author's transl)]. PMID- 4142192 TI - [Electron microscopy in cytological diagnosis of effusions (author's transl)]. PMID- 4142191 TI - [Comparing investigations of the cytology and histology of brain tumors (author's transl)]. PMID- 4142193 TI - [The cytological behaviour of primary malignant tumors of bone (author's transl)]. PMID- 4142194 TI - [Case demonstration of the cytological diagnosis of primary and secundary tumors of bone (author's transl)]. PMID- 4142195 TI - [Comparative study of histologic and cytologic intraoperative examination (author's transl)]. PMID- 4142196 TI - [Some aspects of aspiration biopsy value in radiotherapy (author's transl)]. PMID- 4142197 TI - [Quantitative expression of diagnostic efficiency in applied cytology (author's transl)]. PMID- 4142198 TI - [Differentiation of different lymphocytes by alkaline phosphatase--the cytochemical parameter of alkaline phosphatase in relation to T- and B lymphocytes in Clethrionomys glareolus (author's transl)]. PMID- 4142199 TI - [Cellular changes of gastric ulcer in exfoliative cytology (author's transl)]. PMID- 4142200 TI - [Experiences with the combined use of cytology and histomorphology in the diagnosis of stomach diseases (author's transl)]. PMID- 4142202 TI - [Exfoliative cytology of the urinary system using the millipore filter (author's transl)]. PMID- 4142201 TI - [The value of cytology in the differential diagnosis of suspected permigration of gynaecological malignoma into the urinary bladder (author's transl)]. PMID- 4142203 TI - [Clinical experiences and advantages with aspiration biopsy of the prostate (author's transl)]. PMID- 4142204 TI - [Comparison of histological and cytological studies of the prostate with special reference to oestrogene induced changes (author's transl)]. PMID- 4142205 TI - [Determination of proliferative activity of human prostatic needle biopsies by means of 3H-thymidine autoradiography (author's transl)]. PMID- 4142206 TI - [Cell types in carcinoma of the prostate. Comparison of light and electron microscopical findings (author's transl)]. PMID- 4142207 TI - [Cytological and electron microscopical researches in needle biopsies of the prostate (author's transl)]. PMID- 4142208 TI - [The appearance of prostatic carcinomas in combined aspiration and coarse needle biopsies (author's transl)]. PMID- 4142209 TI - [The total nuclear dry mass as a point of reference in cytology (report) (author's transl)]. PMID- 4142210 TI - [Granulomatous prostatitis in aspiration biopsy smears (author's transl)]. PMID- 4142211 TI - [Cytologic changes in aspiration biopsy smears from various conditions of the thyroid treated with radioiodine (author's transl)]. PMID- 4142213 TI - [Cytochemical observations of pigment-containing phagocytes in thyroid gland punctates (author's transl)]. PMID- 4142212 TI - [Cytological differentiation of malignant tumors of the thyroid. (A comparison of cytological and histological findings) (author's transl)]. PMID- 4142214 TI - [Prognostic criteria from the ultrastructure of breast tumors (author's transl)]. PMID- 4142215 TI - [Cytological and cytochemical studies on mammilary secretion (author's transl)]. PMID- 4142216 TI - [Cytologic diagnosis of mammary tumors by aspiration biopsy (author's transl)]. PMID- 4142217 TI - [Comparative histologic and cytologic examination of breast biopsies (author's transl)]. PMID- 4142218 TI - [Exfoliativ cytology as supplement to the histological diagnosis of mamma excisions (author's transl)]. PMID- 4142219 TI - [The comparison of the results between cytologic and histologic signs in 921 malignant tumors from 2500 biopsy materials in thorax (author's transl)]. PMID- 4142220 TI - [The transthoracic needle biopsy of the lung (author's transl)]. PMID- 4142221 TI - [Cytological studies to verify preneoplastic and neoplastic alterations of the larynx (author's transl)]. PMID- 4142222 TI - [The cytological diagnosis of malignancies of the nasopharynx (author's transl)]. PMID- 4142223 TI - [Cytodiagnosis of localized tumors in the pancreas by means of fine needle biopsy during operation (author's transl)]. PMID- 4142224 TI - [Cytology of the pancreas and it's neoplasms by means of fine needle aspiration biopsy during peritoneoscopy (author's transl)]. PMID- 4142225 TI - [Proceedings: Combined coronary angiography, mascroscopy and microscopy studies of the human heart]. PMID- 4142226 TI - [Proceedings: Postmortem coronary angiography and morphology findings following aorto-coronary bypass surgery]. PMID- 4142227 TI - [Proceedings: Experimental myocardial necrosis due to normobaric hyperoxia]. PMID- 4142228 TI - [Proceedings: Proliferation kinetics in parenchymal organs and in the intestinal epitelium of juvenile rats]. PMID- 4142229 TI - [Proceedings: Cytomorphologic and enzyme-histochemical aspects of intestinal mucosa in absolute hunger condition]. PMID- 4142230 TI - [Proceedings: Cellular and biophysical findings in the cortical substance of the femur in secondary hyperparathyroidism]. PMID- 4142231 TI - [Proceedings: Relationship between bone cell "activity" and loss of bone substance due to age]. PMID- 4142232 TI - [Proceedings: Hypertensive glomerular lesions]. PMID- 4142233 TI - [Proceedings: Renin secretion and juxtaglomerular apparatus in folic-acid-induced kidney failure in the rat]. PMID- 4142234 TI - [Proceedings: Intraepithelial filaments in the human kidney]. PMID- 4142235 TI - [Proceedings: Radiation effects on the proliferation of kidney epithelium following lead administration in connection with nephrectomy and temporary ischemia]. PMID- 4142236 TI - [Proceedings: Perimembranous glomerulonephritis in diabetes mellitus]. PMID- 4142237 TI - [Proceedings: Ultrastructure of osteocytes in the tibial cortex of the rat]. PMID- 4142238 TI - [Proceedings: Morphometry of placental insufficiency]. PMID- 4142239 TI - [Proceedings: Artificially created giant mitochondria filled with matrix in hepatocytes]. PMID- 4142240 TI - [Proceedings: Effect of diethylnitrosamine on cytoplasmic protein synthesis in the rat]. PMID- 4142241 TI - [Proceedings: Cell nucleus picture of fat cells under various functional condition]. PMID- 4142242 TI - [Proceedings: Single- and impulse cytophotometry studies on transplantation tumors]. PMID- 4142243 TI - [Proceedings: Histological and cytological diagnosis of myelosarcomas]. PMID- 4142244 TI - [Proceedings: Patho-anatomical findings in metastasizing tumors with microangiopathic hemolytic anemia]. PMID- 4142245 TI - [Proceedings: Nucleus changes following mitosis disorders]. PMID- 4142246 TI - [Proceedings: Binding of DNA to the nuclear membrane in growing and resting 3T3 cells]. PMID- 4142247 TI - Proceedings: Thymidine incorporation in excision tissue following several hours of incubation. PMID- 4142248 TI - [Proceedings: Cytological detection of glia-specific S-100 protein in neurogenic tumors]. PMID- 4142249 TI - [Proceedings: Activity of beta-glucuronidase in epithelial proliferation of the mammary gland especially in carcinoma]. PMID- 4142250 TI - [Proceedings: Comparative studies of chromosome stripe pattern in Giemsa and fluorescent staining of gonosomal and somatic cells in Chinese hamsters]. PMID- 4142251 TI - [Proceedings: Experimental scanning electron microscopy studies on resorption of cells from the intraperitoneal space]. PMID- 4142252 TI - Proceedings: Induced growth of connective tissue in long-term and short-term studies. PMID- 4142253 TI - [Proceedings: Transplantable leukemia in mice: leukemogenesis and virus synthesis in the liver of the host animal]. PMID- 4142254 TI - [Proceedings: Autoradiography studies on RNA-metabolism in the Ehrlich ascite tumor of the mouse during isoprenaline administration]. PMID- 4142255 TI - [Proceedings: Amyloid tumor with special tissue necrosis]. PMID- 4142256 TI - [Proceedings: Histology and electron microscopy findings in tumor-forming amyloidosis]. PMID- 4142257 TI - [Proceedings: Ultrastructure of the so-called malignant meningiomas]. PMID- 4142258 TI - [Proceedings: Epitheloid sarcoma]. PMID- 4142259 TI - [Cytophotometry in cytology (report) (author's transl)]. PMID- 4142260 TI - [Proceedings: Carcinoembryonal Antigen (CEA) and blood group substances in stomach carcinoma]. PMID- 4142261 TI - [Proceedings: Transformation of fibroblasts in vitro by beryllium]. PMID- 4142262 TI - [Proceedings: Pathomorphological incidence distribution and classification problems in breast carcinoma]. PMID- 4142263 TI - [Proceedings: Functional and morphological studies on standardized hemorrhagic shock in the rat]. PMID- 4142264 TI - [Proceedings: Fate of lyophilized tissue implants]. PMID- 4142265 TI - [Proceedings: Cell changes resembling lipidosis in the rat following treatment with thymoleptics]. PMID- 4142266 TI - [Proceedings: Spleen lymphocytes in "nude" mice with congenital thymus defect]. PMID- 4142267 TI - [Proceedings: The defenseless organism. Organ findings in serum-dependent dysfunction of granulocytes]. PMID- 4142268 TI - [Proceedings: Spleen macrophages in idiopathic thrombocytopenic purpura--an electron microscopy study]. PMID- 4142269 TI - [Proceedings: Morphological, biochemical, mathematical and statistical studies on rat hearts following experimental blockage of thoracic duct]. PMID- 4142270 TI - [Proceedings: Morphological changes in the right atrium especially in cor pulmonale]. PMID- 4142271 TI - [Proceedings: Arterial valve formation in renal hypertension and adaptation to high altitude]. PMID- 4142272 TI - [Proceedings: Histometric studies on perfusion-fixed arteries of man during various pressure conditions]. PMID- 4142273 TI - [Proceedings: Formal pathogenesis of so-called basophilic degeneration in the human myocardium]. PMID- 4142274 TI - [Proceedings: Interference and polarization microscopy studies on dog hearts following the use of ameroid constrictors]. PMID- 4142275 TI - [Proceedings: Fluorescence-cytophotometry studies on action mechanism of estradiol benzoate on liver cell nuclei in rats]. PMID- 4142276 TI - [Proceedings: Electron microscopy studies of the liver-cell membrane in phalloidine poisoning]. PMID- 4142278 TI - [Proceedings: Intracisternal hyalin in human liver biopsy]. PMID- 4142277 TI - [Proceedings: Effect of phenobarbital on liver-cell proliferation following partial hepatectomy]. PMID- 4142279 TI - [Proceedings: Submicroscopic changes in the alveolar region of lungs following sendai virus infection]. PMID- 4142280 TI - [Proceedings: Oxygen-induced pulmonary hyalin membranes (PHM) and plasmatic hyperkoagulation]. PMID- 4142281 TI - [Proceedings: Scanning electron microscopy studies on the surface ultrastructure of the rat lung and trachea]. PMID- 4142282 TI - [Proceedings: Tuberculosis as a natural science problem]. PMID- 4142283 TI - [Proceedings: Early ultrastructural changes in the lung during acute intracranial pressure increase]. PMID- 4142284 TI - [Proceedings: Comparative histochemical and disc-electrophoretic studies on postnatal differentiation of intestinal mucosa enzymes]. PMID- 4142285 TI - [Proceedings: Morphological findings on the role of Paneth's cells in enteral calcium secretion]. PMID- 4142286 TI - [Proceedings: Ultrastructure of endocrine cells in human gastric mucosa]. PMID- 4142287 TI - [Proceedings: Subclassification in early gastric cancer]. PMID- 4142288 TI - [Proceedings: Isolated panarteritis of the appendix]. PMID- 4142289 TI - [Proceedings: Experimental parotid changes following chemically induced sympaticus degeneration]. PMID- 4142290 TI - [Proceedings: Light and electron microscopy studies on biopsies of the small intestine in acrodermatitis enteropathica]. PMID- 4142291 TI - [Proceedings: Electron microscopy studies on the pathogenesis of uremic gastropathy]. PMID- 4142292 TI - [Proceedings: Rare observation of endogenous clostridium infection]. PMID- 4142293 TI - [Proceedings: Mucocutaneous histoplasmosis. Light and electron microscopy findings]. PMID- 4142294 TI - [Proceedings: Case report with light and electron microscopy studies of urinary bladder rhabdomyosarcoma in an eight-month-old girl]. PMID- 4142295 TI - [Proceedings: Existence of lobular glomerulonephritis]. PMID- 4142296 TI - [Proceedings: Membrane-proliferating glomerulonephritis]. PMID- 4142297 TI - [Proceedings: Quantitative morphology of the juxtaglomerular apparatus in perimembrane glomerulonephritis]. PMID- 4142298 TI - [Proceedings: Pathomorphology of focally and segmentally sclerosing glomerulonephritis]. PMID- 4142299 TI - [Proceedings: Tubular inclusions of the renal endothelium in lupus erythematosus and familial nephrotic syndrome]. PMID- 4142300 TI - [Proceedings: Kidney regeneration following subtotal (5/6-)nephrectomy. Autoradiographic studies]. PMID- 4142301 TI - [Proceedings: Principles of a pathohistological classification of glomerulonephritis]. PMID- 4142302 TI - [Proceedings: Trace element content of the ovary]. PMID- 4142303 TI - [Proceedings: Light and electron microscopy findings on the infiltrating growth of prostatic carcinoma]. PMID- 4142304 TI - [Proceedings: Morphology of histiocytic granulomatous prostatitis]. PMID- 4142305 TI - [Proceedings: Light and immunofluorescence microscopy studies on the etiology of fibrinoid necroses in the human placenta]. PMID- 4142306 TI - [Proceedings: Early ultrastructural changes in the tibia metaphysis of the mouse following incorporation of Ra-224]. PMID- 4142307 TI - [Proceedings: Mineral pathology of the bone]. PMID- 4142308 TI - [Proceedings: Morphological studies on the pathogenesis of uremic epiphysiolysis]. PMID- 4142309 TI - [Proceedings: Malignant bone tumors. Clinical and morphological observations of 308 cases]. PMID- 4142310 TI - [Proceedings: Ultrastructural studies on the rat hypophysis following administration of cortisol-synthesis inhibitors and methylprednisolone]. PMID- 4142311 TI - [Proceedings: Significance of calcium transport for the function of B-cells of the island system]. PMID- 4142312 TI - [Proceedings: Effect of vitamin D, dehydrotachysterine and parathyroid hormone on calcium metabolism in the rat]. PMID- 4142313 TI - [Proceedings: Causative pathogenesis and morphology of thyroid tumors in the rat]. PMID- 4142314 TI - [Proceedings: Architecture of interstitial Leydig cells and their ultrastructure following administration of anti-androgen in the rat]. PMID- 4142315 TI - [Proceedings: Significance of fatty degeneration of glia cells of the cerebral medullary substance in the infant]. PMID- 4142316 TI - [In memory of Bernhard Veit (6,1, 1882-2, 10, 1963)]. PMID- 4142317 TI - [In memory of Herbert J. Schott (9,1, 1929-8,9, 1971)]. PMID- 4142318 TI - [In memory of Karl Th. Neubuerger (3,5, 1890-3,7, 1972)]. PMID- 4142319 TI - [In memory of Heinrich Muller (1,8, 1884-7,31,1972)]. PMID- 4142320 TI - [In memory of Hans Rudolf Dohnert (8,4, 1908-9,8, 1972)]. PMID- 4142321 TI - [In memory of Karl Husten (12,19, 1892-10,14,1973)]. PMID- 4142322 TI - [In memory of Richard Bohmig (4,6, 1898-10,17, 1972)]. PMID- 4142323 TI - [In memory of Alexander Symeonides (8,29, 1909-11,16, 1972)]. PMID- 4142324 TI - [In memory of Marie-Luise Trautmann (2,13, 1921-12,6, 1972)]. PMID- 4142325 TI - [In memory of Paul Moegen (7,3, 1904-2,11, 1973)]. PMID- 4142326 TI - [In memory of Eugen Kirch (3,10, 1888-4,2, 1973)]. PMID- 4142327 TI - [In memory of Willy Giese (12,18, 1902-3,4, 1973)]. PMID- 4142328 TI - [In memory of Tomizo Yoshida (2,10, 1903-4,27, 1973)]. PMID- 4142329 TI - [German Society for Pathology. List of members]. PMID- 4142330 TI - [Cytogenetics and cytology in malignant disease (report) (author's transl)]. PMID- 4142331 TI - [Cytoplasmic aspects in oncocytology (report) (author's transl)]. PMID- 4142332 TI - [The evaluation of ultrastructure for the diagnosis of tumors (report) (author's transl)]. PMID- 4142333 TI - [Enzyme histochemistry in tumour diagnosis (report) (author's transl)]. PMID- 4142334 TI - [Applied exfoliative cytology of bronchial system (report) (author's transl)]. PMID- 4142335 TI - [Exfoliative cytology of effusions (report) (author's transl)]. PMID- 4142336 TI - [Physiopathological action of aldehydes in atmospheric pollution (author's transl)]. PMID- 4142337 TI - [Methods of measuring aldehydes in the urban atmosphere. Results ]. PMID- 4142338 TI - [Aldehydes in residual engines gases (author's transl)]. PMID- 4142339 TI - [The role of lead as an atmospheric polluant (author's transl)]. PMID- 4142340 TI - Lindane residues in the southern coastal aquifer of Israel. PMID- 4142341 TI - Increased aromatics in motor fuels: a review of the environmental and health effects. PMID- 4142342 TI - Experimental infection by respiratory route of non-immunized mice exposed to atmosphere contaminated by auto exhaust. PMID- 4142343 TI - [Detection of osteoid tissues and degenerated intercellular bone substance using a modification of the hematoxylin-cosin staining technique (author's transl)]. PMID- 4142344 TI - [The significance of liver biopsy for the recognition of the alcoholic liver damage clinically manifesting (author's transl)]. PMID- 4142345 TI - ["Sarcoid-like lesions" of the spleen in malignant tumors (author's transl)]. PMID- 4142346 TI - [Fluorescence and Giemsa-banding in a case of Patau's syndrome]. PMID- 4142347 TI - [Therapy for cervix carcinoma at the Gynecological Hospital Dresden Friedrichstadt in 1950-1967. I]. PMID- 4142348 TI - [Thyroid gland activity after anti-brucellosis immunization and in experimental brucellosis]. PMID- 4142349 TI - [Therapeutic aspects of intestinal bacterial pathology]. PMID- 4142350 TI - Nature of the antigammaglobulin activity in cryoglobulinemic disorders. PMID- 4142351 TI - Ultrastructure of developing cartilage in the mandibular condyle of the mouse. PMID- 4142352 TI - Accumulation and autophagic degradation of glycogen in the mouse cervicovaginal anlage. With remarks on epithelial heterophagy. PMID- 4142353 TI - The localization within the dorsal motor nucleus of the vagus in the buffalo (Bubalus bubalis). PMID- 4142354 TI - Changes in aminopeptidase activity in the palatal mucosa and gingiva of the rat following tooth extractions. PMID- 4142355 TI - Radioimmunological and autoradiographical studies on the alpha-1-fetoprotein in the obstetrics and gynecology. PMID- 4142356 TI - Glomerular ultrastructure in extracapillary glomerulonephritis. PMID- 4142357 TI - Extracapillary glomerulonephritis. A semiquantitative lightmicroscopical study of 59 patients. PMID- 4142358 TI - The influence of zinc ions administered in vivo on guinea pig anaphylaxis. PMID- 4142359 TI - Immunological properties of two fetus-specific globulins of rat in experimentally induced hepatic lesions. PMID- 4142360 TI - Combination chemotherapy with anticancer agents and OK-432. PMID- 4142361 TI - Studies on the host-mediated action of the streptococcal preparation, OK-432, in cancer chemotherapy. PMID- 4142362 TI - Histochemical observations on the excretory system of digenetic trematodes. PMID- 4142363 TI - The role of macrophages in defense against neoplastic disease. PMID- 4142364 TI - Principles of immunological tolerance and immunocyte receptor blockade. PMID- 4142365 TI - [Possibilities of the utilization of fluorogestone acetate (FGA) given orally for the synchronization of estrus in cattles]. PMID- 4142366 TI - [The ovarian interstitial gland of the hedgehog: morphology, histogenesis, hyperplasia and steroidogenic enzymes]. PMID- 4142367 TI - [Separation of mobile spermatozoa from other cells and cellular debris present in bovine semen]. PMID- 4142368 TI - [Therapeutic trials in amino acid disorders]. PMID- 4142369 TI - Envelope protein alterations in a conditional mutant of Klebsiella pneumoniae with pH dependent morphology and temperature dependent division. PMID- 4142370 TI - Human immunoglobulin light chain subgroups: serological typing. PMID- 4142371 TI - Suppression and patterns of recovery of serum immunoglobulins in mice treated with antibody directed against the constant region of heavy chains. PMID- 4142372 TI - [A comparative study of 2 sensitive methods: radioimmunoassay and enzyme immunoassay for the detection of alpha2H globulin in serum (author's transl)]. PMID- 4142373 TI - [Changes in the specificity of antibodies appearing in the beginning of immunization by "Salmonella senftenberg" (author's transl)]. PMID- 4142374 TI - Isolation of a specific plasmacytoma tumor antigen, reactive both in humoral and cell mediated immunity. PMID- 4142375 TI - Recent developments in control of blackflies. PMID- 4142376 TI - [Optical properties of actinomycins that differ in amino acid makeup]. PMID- 4142377 TI - [Study of the antigenic makeup of some producers of oxytetracycline using an immunoelectrophoretic method]. PMID- 4142378 TI - Lymphomatoid papulosis. An ultrastructural study of 2 cases. PMID- 4142379 TI - [Experimental model for producing and studying the fate of dilysosomal macrophages in inflammation]. PMID- 4142380 TI - [Cassette method of staining paraffin sections]. PMID- 4142381 TI - [Zinc chemography in histological structures of the pancreas]. PMID- 4142382 TI - [Processing of archival autopsy material for electron microscopy]. PMID- 4142383 TI - [Ultrahistochemical representation of the cell coat at the supporting and the neurosensory cells of the guineapigs cochlea by means of the rutheniumred contrastation (author's transl)]. PMID- 4142384 TI - The connnective tissue in the middle ear mucosa of the guinea pig. PMID- 4142385 TI - Structure and specific antigens of avian leukosis viruses. PMID- 4142386 TI - Changes at the membranes of leukosis virus transformed cells and virus as detected by electronmicroscopy. PMID- 4142387 TI - The role of genetics in Gross virus leukemogenesis. PMID- 4142388 TI - Physical alterations of a murine leukemia virus complex in mammalian cell cultures. PMID- 4142389 TI - Transformation of a cloned renal epithelial cell line by Moloney murine sarcoma virus (M-MSV). PMID- 4142390 TI - The thymus glands and lymphosarcoma in the pike, Esox lucius L. (pisces; esocidae) in Ireland. PMID- 4142391 TI - Focal differences in lipid metabolism of the young pig aorta. Synthesis from [1 14C]acetate and [U-14C]glucose in vitro. PMID- 4142392 TI - Quantitative method for the evaluation of atherosclerotic lesions. PMID- 4142393 TI - [Capsular structures in Klebsiella pneumoniae]. PMID- 4142394 TI - [Staining of lipoproteins for determination of the lipoelectropherogram on cellulose acetate: technical innovations]. PMID- 4142395 TI - Host-virus interactions in murine mammary carcinogenesis. PMID- 4142397 TI - [Analysis of a possible mechanism of extrasystole formation during local myocardial ischemia using a mathematical model]. PMID- 4142396 TI - Organization and communication in populations of normal and leukemic hemopoietic cells. PMID- 4142398 TI - [Use of x-ray structural analysis data for evaluating the contribution of beta structures to the optical rotatory dispersion of proteins]. PMID- 4142399 TI - Updating advances in cytogenetics. PMID- 4142400 TI - Chromosomal abnormality (46,XX,3p plus) in a case of the Meckel syndrome. PMID- 4142401 TI - An in vitro system for studying the spontaneous occurrence of trisomics. PMID- 4142402 TI - Updating advances in cytogenetics. Applications of the new chromosome banding methods. PMID- 4142403 TI - [Malignant non-hodgkinian hematosarcomas (lymphomae) in the adult. Chemoradiotherapy applied to stages and/or topographic forms III and IV]. PMID- 4142404 TI - [Chemotherapy of reticulosarcomas and lymphosarcomas. A 10-year analysis]. PMID- 4142405 TI - The axonal transport of (3H)fucose labelled glycoproteins in normal and regenerating peripheral nerves. PMID- 4142406 TI - [Radioimmunologic assay of plasma alpha-feto-protein in the pregnant woman]. PMID- 4142407 TI - The location of the positions of the breakpoints involved in the T26H and T70H mouse translocations with the aid of Giemsa-banding. PMID- 4142408 TI - Chromosomes of the Mexican plateau mouse, Peromyscus melanophrys, and a new sex determining mechanism in mammals. PMID- 4142409 TI - Significance of coupling intervals of ventricular extrasystoles. AB - Extrasystoles may have fixed or variable coupling intervals. The latter may be divided into those with coupling intervals related to and following the T wave of the preceding QRS (approximate coupling) and those which occur throughout electrical diastole with no obvious relationship to the T wave of the dominant rhythm (random coupling). Extrasystoles with random and approximate coupling may or may not be parasystolic. The relationship of extrasystoles to the dominant rhythm may alter. In particular, fixed coupling may precede or alternate with approximate coupling. These groups cannot be considered distinct, in view of transitions from one type of extrasystole to another. Extrasystoles with both approximate coupling and fixed coupling tend to occur just after the T wave and often occurred on the apex of the U wave. Approximate non-parasystolic coupling was infrequent in electrocardiograms which were otherwise normal. Random non parasystolic coupling and parasystole only occurred in patients with cardiac disease. In view of these findings, it is proposed that extrasystoles should be described by their degree of dependence on each other (regularity of interectopic intervals) and their degree of dependence on conducted beats (regularity of coupling intervals), PMID- 4142410 TI - Ventriculo-atrial conduction associated with ventricular premature beats. Study with his bundle electrography. AB - In a group of eight patients with ventricular premature beats, ventriculoatrial conduction, with retrograde activation of the His bundle and the atria could be demonstrated by His bundle electrograms in four subjects. All had early ventricular premature beats with coupling indices between 210 and 350 msec. In the other four cases, concealed retrograde conduction could be demonstrated in the A-V nodal area. The ventricular ectopic beats were late, and depending upon the refractory period of the A-V node these extrasystoles were interpolated or followed by compensatory pauses. PMID- 4142411 TI - The aesthetes of chitons. II. Fine structure in Lepidochitona cinereus (L.). PMID- 4142412 TI - Cellular aspects of tolerance. III. The responsiveness of T cells from tolerant donors after exposure to a cross-reacting antigen. PMID- 4142413 TI - Cellular aspects of tolerance. IV. Strain variations of tolerance induceability. PMID- 4142414 TI - Rat B cells: identity of immunoglobulin-bearing cells with a population of lightly uridine-labeled cells. PMID- 4142415 TI - Experimental allergic encephalomyelitis and cellular immunity in the Lewis rat. PMID- 4142416 TI - Cellular aspects of tolerance. V. The in vivo cooperative role of accessory and thymus derived cells in responsiveness and unresponsiveness of SJL mice. PMID- 4142417 TI - Cellular aspects of tolerance. VI. The effect of age on responsiveness and tolerance induceability of SJL mice. PMID- 4142418 TI - Cellular aspects of tolerance. VII. Inheritance of the resistance to tolerance induction. PMID- 4142419 TI - Cellular analysis of the phenotypic correction of the genetically controlled low immune response to the polyproline determinant by macrophages. PMID- 4142420 TI - Effect of rabbit interferon on immune responses. PMID- 4142421 TI - Influence of heparin and protamine on enlargement of the draining lymph node during induction of EAE. PMID- 4142422 TI - Experimental allergic encephalomyelitis: changes in growth and proliferation within the draining lymph node following injection of basic encephalitogenic protein in Freund's complete adjuvant. PMID- 4142423 TI - Immune protection against experimental autoimmune encephalomyelitis: optimal conditions and analysis of mechanism. PMID- 4142424 TI - Antigen modulation of the immune response. III. Evaluation of the hypothetical short-lived memory cell. PMID- 4142425 TI - Surface immunoglobulin on rabbit lymphoid cells. I. Ultrastructural distribution and endocytosis of b4 allotypic determinants on peripheral blood lymphocytes. PMID- 4142426 TI - Surface immunoglobulin on rabbit lymphoid cells. II. Ultrastructural distribution of b4 allotypic determinants and morphology of spleen lymphocytes. PMID- 4142427 TI - [Genetic adaptation to ethanol: an important parameter in the evolution of geographic races of Drosophila melanogaster]. PMID- 4142428 TI - [Isolation, physical properties and morphology in electron microscopy of rat serum alpha-1-macroglobulin]. PMID- 4142429 TI - [Determination of the distribution of gamma fusimotor axons in the cat by glycogenic depletion]. PMID- 4142430 TI - [Immunological and biological study of subunits of tetanus toxin]. PMID- 4142431 TI - Comparative study of histamine release by cotton dust from the lung of several species. PMID- 4142432 TI - Circadian rhythms: some examples and comments on clinical application. PMID- 4142433 TI - Which antibiotic for acute otitis media? PMID- 4142434 TI - [Cholestatic icterus after intake of ovulation inhibitors]. PMID- 4142435 TI - [Investigations on the influence of ovulation inhibitors on the development and prognosis of chronic hepatopathies]. PMID- 4142436 TI - Radioisotope studies in thyrotoxicosis at Mulago, Kampala. PMID- 4142437 TI - Long-term administration of 3,5-diodo-4(3'-iodo4'-acetoxyphenoxy) benzoic acid (acetiromate) in hyperlipidemic patients. PMID- 4142438 TI - Quantitation of ovalbumin mRNA in hen and chick oviduct by hybridization to complementary DNA. Accumulation of specific mRNA in response to estradiol. PMID- 4142439 TI - [Reading--listening--seeing? Which information reaches the profession most effectively?]. PMID- 4142440 TI - Studies on the acute and long-term oral toxicity fo chlorpyrifos (0,0-diethyl 0(3,5,6-trichloro-2-pyridyl) phosphorothioate). PMID- 4142441 TI - Monographs on fragrance raw materials. PMID- 4142442 TI - Comparative studies on human and rabbit exocrine IgA antibodies to an albumin. PMID- 4142443 TI - Experimental allergic encephalomyelitis: structural specificity of determinants for delayed hypersensitivity. PMID- 4142444 TI - On the mechanism of hemolytic plaque inhibition. PMID- 4142445 TI - Effect of haptoglobin on immunological activity of hemoglobin. PMID- 4142447 TI - Antigenic homology between a marsupial homocytotropic antibody and human IgE. PMID- 4142446 TI - Distribution of antibody affinities. II. Fractionation of antibody with respect to its hapten binding affinity. PMID- 4142448 TI - Immunological unresponsiveness induced in adult mice to synthetic polypeptides built on multichain polyproline and multichain polyalanine. PMID- 4142449 TI - The separation of rabbit anti-dinitrophenyl IgG antibodies on the basis of combining site depth. PMID- 4142450 TI - Critical antigenic determinants for production of antibody to distinguish morphine from heroin, codeine and dextromethorphan. PMID- 4142451 TI - Naturally-occurring antibodies reacting with some buried determinants of homologous IgG exposed by spleen protease digestion. PMID- 4142452 TI - Enzymic and immunochemical properties of lysozyme--VIII. Modification of two carboxyl groups and their role in the antigenic reactivity. PMID- 4142453 TI - The anti-I activity of the Sophora japonica lectin. PMID- 4142454 TI - Released myelin basic protein: the immunogenic factor? PMID- 4142455 TI - Allotypic marker of kappa light chains of rat immunoglobulins localized in the constant region of the chain. PMID- 4142456 TI - The immunochemistry of a linear polymer and a branched copolymer containing the sequence Glu-Lys-Ala-Gly. PMID- 4142457 TI - A radioimmunoassay specific for the antigenic determinants exposed by pepsin digestion of human immunoglobulin G. PMID- 4142458 TI - An immunoenzymatic method for measuring low concentrations of antigens by single radial diffusion. PMID- 4142459 TI - Allotypes of rat immunoglobulins. II. Distribution of the allotypes of kappa and alpha chain loci in different inbred strains of rats. PMID- 4142460 TI - Report of the workshop on the carcinoembryonic antigen (cea): the present position and proposals for future investigation. PMID- 4142461 TI - Transplantation immunity to individually unique antigens of chemically induced bladder tumors in mice. PMID- 4142462 TI - Control of normal differentiation of myeloid leukemic cells. V. Normal differentiation in aneuploid leukemic cells and the chromosome banding pattern of D+ and D minus clones. PMID- 4142463 TI - Natural expression of feline type-C virus genomes, prevalence of detectable felv and RD-114 GS antigen, type-C particles and infectious virus in postnatal and fetal cats. PMID- 4142464 TI - Fetal proteins occurring in testicular teratomas. PMID- 4142465 TI - Influence of 5-bromodeoxyuridine on the expression of avian gs antigen in mammalian rous sarcoma virus-transformed cells. PMID- 4142466 TI - Immunogenicity, antigenicity and mechanisms of tumor rejection of mineral-oil induced plasmacytomas in syngeneic BALB/c mice. PMID- 4142467 TI - Specific and non-specific immunologic reactivity of regional lymph-node lymphocytes in human malignancy. PMID- 4142468 TI - Cellular immune response to virus-specific antigen in hamsters bearing isografts of cytomegalovirus-transformed cells. PMID- 4142469 TI - [Immunochemical identification of beta1-globulin of the "pregnancy zone" in serum of patients with trophoblastic tumors]. PMID- 4142470 TI - Report of the scientific meeting on some developments in the methodology of controlled clinical trials in cancer. PMID- 4142471 TI - Demonstration of Epstein-Barr virus-associated nuclear antigen in nasopharyngeal carcinoma cells from fresh biopsies. PMID- 4142472 TI - Distinctive properties of thymidine kinase isozymes induced by human and avian hepresviruses. PMID- 4142473 TI - Cell surface antigen induced by avian tumor viruses in hamster cells transformed by a temperature-sensitive mutant of Rous sarcoma virus. PMID- 4142474 TI - Specific tumor-induced suppression of lymphocyte activity in the antibody dependent tumoricidal reaction. PMID- 4142475 TI - Histochemical study of Erythema nodosum leprosum (ENL) lesions. AB - A histochemical study of ENL lesions was performed on skin biopsies from 14 leproma-tous patients. There was: 1) the presence of moderate amounts of PAS positive diastase resistant materials, acid mucopolysaccharide, neutral fat, phospholipid, aryl sulfatase and acid phosphatase in areas around and away from reactional sites; 2) the presence of slight amounts or complete absence of these materials within areas of acute inflammation. These changes were interpreted as the result of solubilization and leakage of hydrolytic enzymes into the surrounding tissue. A possible role of lysosomal enzymes in the pathogenesis of ENL lesions is discussed. PMID- 4142476 TI - Acid mucopolysaccharide metabolism in leprosy. 1. Storage of hyaluronic acid and its possible significance in the pathogenesis of leprosy. AB - A histochemical analysis of 102 skin biopsies from a variety of leprosy types revealed the persistent presence of hyaluronic acid in lepra cells of lepromas. In contrast, the hyaluronic acid content of tuberculoid epithelioid cells showed a minimum amount of hyaluronic acid and hyaluronic acid tended to disappear from these granulomas as they aged. The macrophages of dimorphous leprosy occupied an intermediate position with respect to hyaluronic acid content and distribution, resembling the tuberculoid in BT cases and the lepromatous expression in BL cases. It is suggested that hyaluronic acid, in a manner similar to M. leprae and lipid, has a quantitatively varied distribution reflecting the immunopathologic spectrum of leprosy. This finding suggests that acid mucopolysaccharide may be significantly involved in that host/parasite interaction in leprosy. PMID- 4142477 TI - The antigenic determinants of several human plasma proteins. Their determination from the investigation of the cross-reactions between human and other mammalian plasmas. PMID- 4142478 TI - Antigenic activity of hemeundecapeptide and hemeoctapeptide obtained from cytochrome c. PMID- 4142479 TI - Studies on inherited antigenic variation of human serum beta-lipoprotein by passive hemagglutination. I. Methodological studies. PMID- 4142480 TI - Characterization of a human pathological immunoglobulin fragmenting during purification. PMID- 4142481 TI - Binding of folic acid to serum proteins. IV In some animal species. PMID- 4142482 TI - Morphological criteria for the control of carcinoma of the prostate with estrogen therapy. PMID- 4142483 TI - Standards of karyology for human diploid cells. PMID- 4142484 TI - Identification of some HBAg (HAA) antigenic determinants by two-dimensional electro-immunodiffusion. PMID- 4142485 TI - [The sulcus ulnaris Syndrome. Nerve Conduction Studies and Results of Anterior Transposition of the Ulnar Nerve]. PMID- 4142486 TI - [Further Results from Scintigraphy of Extracranial Carotid Thrombosis with Special Attention to Cerebral Insults[]. PMID- 4142487 TI - Needle Myopathy--An Experimental Study. PMID- 4142488 TI - The course of a model cutaneous inflammation in the scapuloperoneal syndrome and in systemic neuromuscular diseases. PMID- 4142489 TI - [The Relationship between disorders of bladder and bowel function and neurological symptomatology with spinal lesions]. PMID- 4142490 TI - Neurology in India. PMID- 4142492 TI - A macroscopic study of plaque morphogenesis. PMID- 4142491 TI - [Electrical and mechanical Muscle Reaction in Adynamia episodica and Paramyotonia congenita after Cooling and Administration of Potassium]. PMID- 4142493 TI - In vivo LE cell formation in peritonitis due to systemic lupus erythematosus. PMID- 4142494 TI - Gamma globulin complexes in rheumatoid arthritis and hypergammaglobulinemic purpura. PMID- 4142495 TI - The antigenicity of polynucleotides in mink, rabbit, and man. PMID- 4142496 TI - [I-131 absorption by the thyroid gland in hepatolenticular generation]. PMID- 4142497 TI - [Retroperitoneal tumors. Diagnosis etiology and treatment]. PMID- 4142498 TI - Treatment of primary liver carcinoma. PMID- 4142499 TI - [Are the palatal tonsils and appendix in man equivalent to the bursa of Fabricius in birds?]. PMID- 4142500 TI - [Special features in the clinical course and postoperative care in acute appendicitis]. PMID- 4142501 TI - [Method of detection of plague bacilli in histological sections of infected fleas]. PMID- 4142502 TI - [Audio-visual methods in psychiatry]. PMID- 4142503 TI - [A histochemical and electronmicroscopic study of an osteochondroma arising from the posterior clinoid process (author's transl)]. PMID- 4142504 TI - [Histochemical studies of post-traumatic changes of the knee joint menisci]. PMID- 4142505 TI - [How to palliate kidney destruction in children]. PMID- 4142506 TI - [Monoclonal plasmocytic myeloma with 2 paraproteins, IgG kappa and IgG lambdal]. PMID- 4142507 TI - [Radiology in diffuse chronic jejunopathies]. PMID- 4142508 TI - Liver pathomorphology in collagenoses. PMID- 4142509 TI - Developmental assessment of the young child in general practice. PMID- 4142510 TI - Electron microscopic observations of heat-induced changes in the structure of mitochondrial membranes. PMID- 4142511 TI - [Surgical treatment of metastases and metastaic fractures of the long bones. Apropos of 53 palliative osteosynthesis]. PMID- 4142512 TI - [Pathophysiological study of bovine tuberculosis]. PMID- 4142513 TI - Analytical polyacrylamide-gel electrophoresis of aqueous Trypanosoma cruzi extracts. I. Chemical and immunological investigation of Y and Brasil strains antigenic components. PMID- 4142514 TI - [Inflammatory rheumatism in immunologic deficiencies]. AB - The authors give a general review of rheumatic manifestations associated with immunodeficiency in children with reference to 7 personal observations. The review demonstrates the high frequency of this association, the variable clinical picture in one, a few, or many joints, the prolonged, relatively mild evolution that is never deforming or ankylosing, the existence of frequent auto-immune and rheumatic manifestations in families, and the usual but variable effectiveness of gammaglobulins. The possibility of immunodeficiency should be considered in cases of mono-, oligo-, and polyarthritis. The results of humoral and cellular immunological studies demonstrated a low level of immunoglobulins, the presence of nonfunctional B cells, and the presence of T cells that were probably qualitatively modified. A physiopathological interpretation is suggested. PMID- 4142515 TI - [Biochemical changes in the hyperfixating thyroid nodule]. PMID- 4142516 TI - Human muscle nerve sympathetic activity in cardiac arrhythmias. PMID- 4142517 TI - Neutral proteases of human granulocytes. III. Interaction between human granulocyte elastase and plasma protease inhibitors. PMID- 4142518 TI - [My way to inform: Cassette and loose-leaf book simple and cheap alternative]. PMID- 4142519 TI - Sheep progressive pneumonia virsuses: "slow" cytolytic agents with tumor virus properties: A review. PMID- 4142520 TI - Histologic study of the skin of congenitally athymic "nude" mice. PMID- 4142521 TI - Quantitative polyacrylamide gel electrophoresis for cationic proteins from polymorphonuclear (PMN) leukocytes. PMID- 4142522 TI - [Data on toxicity and various therapeutic results of antineoplastic antibiotics in the dog]. PMID- 4142523 TI - [Determination of hypergammaglobulinemia in cattle under practice conditions]. PMID- 4142524 TI - Effect of lobectomy on some parameters of iodine metabolism. PMID- 4142525 TI - Effect of thyroidectomy on the in vitro utilization of glucose by hypophysis and hypothalamus in the rat. PMID- 4142526 TI - Immunoflorescence studies of Leishmania enriettii infection in the guinea pig. PMID- 4142527 TI - Pioneering audio-visual communication in medical education in Nigeria. PMID- 4142528 TI - [Latest technical development-situation in heart pacemaker therapy]. PMID- 4142529 TI - [Histology of islands of Langerhans cells. Studies and staining tests in normal, cortisone and ACTH-treated guinea pigs]. PMID- 4142530 TI - [Periodic acid-bisulfite-aldehydethionine-positive structures in the ependyma of 3 human brains of various ages]. PMID- 4142531 TI - [Proceedings: Fibrinolysis studies on pulmonary hyaline membranes in vitro]. PMID- 4142532 TI - [Therapeutic procedures in inoperable carcinoma of the bladder]. PMID- 4142534 TI - [About the resorcin-fuchsin stains. II (AUTHOR'S TRANSL)]. PMID- 4142533 TI - [Immunobiology of pregnancy]. PMID- 4142535 TI - Indulin nigrosin elastin stains. Elastin VI. Stains with alcohol-soluble nigrosins and water soluble indulin and nigrosin and their mechanisms: a lipoprotein component? PMID- 4142536 TI - Fixation of mammalian liver in concentrated buffered neutral formaldehyde at different temperatures. PMID- 4142537 TI - Nature of protein component of the cuticle of an arachnid, Palamneus swammerdami. PMID- 4142538 TI - Organization of the myelinated nerve fibres in the iris of the White Leghorn hen. PMID- 4142539 TI - Choledochoduodenal junction in the dromedary. PMID- 4142540 TI - Furunculosis in dogs. Aetiology, pathogenesis and treatment. A clinical study. PMID- 4142541 TI - The action of propanidid on blood histamine content. PMID- 4142542 TI - [The dermo-epidermal junction of the human skin (author's transl)]. PMID- 4142543 TI - The significance of alpha-fetoprotein in the serum of patients with malignant teratomas and related gonadal neoplasms. AB - Sera from eleven patients with gonadal germ cell tumors were tested for alpha fetoprotein (AFP) by counterelectrophoresis. Ovarian neoplasms containing either the endodermal sinus tumor (EST) or dysgerminoma and half of the testicular embryonal carcinomas elaborated the protein into the serum. The presence of AFP in the serum seemed to correlate with early metastasis or a fatal outcome. That the highest levels of AFP were found in cases of EST was in keeping with the theory that the tumor originates in cells of the yolk sac, a principal embryonic site of AFP synthesis. PMID- 4142544 TI - Relation of human blood-groups MN to cancer cell surface antigens and to receptors for oncogenic viruses. AB - It has been shown by us that the human blood-group MN antigenic determinants are not the products of allelomorphic genes as believed so far, but that N is the precursor substance of M and that the allelomorph to the M gene is amorph. The determinant structure of the N antigen is branched and possesses as non-reducing termini beta-d-galactopyranosyl (Gal) and alpha-N-acetylneuraminic acid (NANA) linked to beta-Gal. The M substance differs from N only in that alpha-NANA covers the terminal beta-Gal of the N determinant. Vicia graminea anti-N reacts with terminal beta-Gal of the N antigen as well as its precursor. A human blood-group N-like antigen in the cell surface of the TA3 mammary adenocarcinoma (ascites form) has been found by us. The TA3 cancer occurs as the non-strain specific Ha subline and as the strain-specific St subline. This is the first description of an N-like antigen in a non-primate as well as a tumor. This antigen reacts with Vicia anti-N. In serological specificity the Vicia agglutinin is closely related to the Thomsen-Friedenreich anti-T agglutinin present in most human and animal sera. These sera plus complement kill ordinary TA3-St cells and sialidase-treated Ha cells to less than 95 percent. Untreated TA3-Ha cells are fully resistant even though they absorb cytotoxin. Beta-galactosidase treatment of either Ha or St cells abolishes the killing activity of the sera. The cancer cells absorb anti-T but they lose this capability after exposure to beta-galactosidase. An immunological cross-relationship between the human blood-group MN antigens and the receptor for an oncogenic virus, the avian subgroup B leukosis sarcoma virus has been observed. PMID- 4142545 TI - [Cytochemical and ultrastructural study of non argentaffine gastric endocrine cells of the rabbit during ontogenesis]. PMID- 4142546 TI - [Genetic regulation of immunoglobulin synthesis during immune response]. PMID- 4142547 TI - The genetic mechanisms that control the immune response and antigen recognition. PMID- 4142548 TI - [Allotypy of rabbit immunoglobulins (author's transl)]. PMID- 4142549 TI - The role of thymocytes and bone marrow cells in the genetic control of immune responsiveness to synthetic polypeptides. PMID- 4142550 TI - Genetics of the immune response in inbred and random bred mice against random copolymers of amino acids. PMID- 4142551 TI - Inheritance of fine-specificity in mouse anti-hapten antibodies. PMID- 4142552 TI - Differentiation of the cells which synthesize the immunoglobulins. PMID- 4142553 TI - Role of the cells which originate from the thymus and bone marrow. PMID- 4142554 TI - A comparison of specific antibody and immunoglobulin synthesising immunocytes in peroxidase stimulated lymph nodes. PMID- 4142555 TI - [Production of antibodies with 2 specificities by individual mouse cells]. PMID- 4142556 TI - [Allotyping of human immunoglobulins]. PMID- 4142557 TI - Lymphocyte commitment to Ig allotype and class. PMID- 4142558 TI - Surface-bound immunoglobulin on B-lymphocytes, evidence for allelic exclusion. PMID- 4142559 TI - Variability of immunoglobulins. PMID- 4142560 TI - [The idiotyping of antibodies]. PMID- 4142561 TI - Subgroups, homologies and idiotypes in immunoglobulins. PMID- 4142562 TI - [Parallel stability of V and C regions of immunoglobulin: genetical and functional implications (author's transl)]. PMID- 4142563 TI - On the effect of selective breeding for specific antibody clones in rabbits. PMID- 4142564 TI - Inheritance of idiotypic specificities of rabbit antibodies to group C streptococci. PMID- 4142565 TI - Towards a network theory of the immune system. PMID- 4142566 TI - Allogroups of rabbit Ig heavy chains. PMID- 4142567 TI - [Cross reaction between Aa1 allotypic pattern of rabbit immunoglobulins and anti Aa3 allotypic pattern antibodies]. PMID- 4142568 TI - Three new examples of intragenic hybridization among IgG subclass genes. PMID- 4142570 TI - Allotypy and structure of immunoglobulins. PMID- 4142569 TI - Mouse immunoglobulin allotypes: characterization and use in cellular immunology. PMID- 4142571 TI - Allotypes of light chains of rat immunoglobulins. PMID- 4142572 TI - Peptides with a-locus allotypic determinants. PMID- 4142573 TI - Chemical studies of the heavy chain of rabbit IgG lacking group a allotypic markers. PMID- 4142574 TI - The interaction of actinomycin with DNA. PMID- 4142575 TI - Studies on the mechanism of 5-fluoroorotic acid inhibition of serine dehydratase induction. PMID- 4142576 TI - Improvement of specific fluorescence in the indirect fluorescent antibody method for detecting antinuclear antibodies using Evans blue dye as a counterstain. PMID- 4142577 TI - [Haptoglobin in domestic mammals. III. Haptoglobin content in blood plasma and serum in ruminants and pigs under various physiological conditions]. PMID- 4142578 TI - [Eso-gastric resection in the treatment of hemorrhages due to extrahepatic portal hypertension]. PMID- 4142579 TI - [Viral hepatitis and its multiphasic development. Study of 704 cases followed from 6 to 12 months]. PMID- 4142580 TI - [Comparative characteristics of Alcian Blue and Basic Brown used for the detection of sulfated polysaccharides]. PMID- 4142581 TI - [X-rays as visual materials in teaching human anatomy in a pedagogical institute]. PMID- 4142582 TI - [Siderosomes in hematocornea]. PMID- 4142584 TI - Complications following the early treatment of hand injuries: an analysis of 100 cases. PMID- 4142583 TI - [Juvenile macular degenerations]. PMID- 4142585 TI - The results of radical excision of oral and oropharyngeal cancer requiring pedicle flap reconstruction. PMID- 4142586 TI - Cancer of the rectum: the results of radical resection and the suggested role of lesser procedures in selected cases. PMID- 4142587 TI - The treatment of benign prostatomegaly by injection. PMID- 4142588 TI - [Effect of promotion on the kinetics of acetyl-alpha-chymotrysin solvolysis under the action of added nucleophilic agents]. PMID- 4142589 TI - Autosomal polymorphisms. PMID- 4142590 TI - The supernumerary isochromosome 18 syndrome (+ 18pu). PMID- 4142591 TI - [Isoelectric focusing and immunochemical analysis of the proteins of the anti tetanus serum "Diaferm-3"]. PMID- 4142592 TI - [Overcoming natural alpha-fetoprotein tolerance in rats]. PMID- 4142593 TI - [The influence of the vagus nerves on the hemodynamics and tubular activity of the kidneys]. PMID- 4142594 TI - [The in vitro interaction of cells from immune lymph nodes and intact bone marrow separated by a millipore membrane]. PMID- 4142595 TI - [Immunochemical determination of beta-1-g-globulin in the serum of patients with chorionepithelioma]. PMID- 4142596 TI - Area Health Education as the foundation for a statewide biomedical communications network. AB - In 1972, the Medical University of South Carolina was awarded a contract to establish four Area Health Education Centers in South Carolina. These centers, based in community hospitals, provide residency programs and clinical instruction for medical, dental, nursing, pharmacy, and allied health students and continuing educational programs for health professionals. A plan for delivering library and other information services to the designated Area Health Education Centers is described. PMID- 4142597 TI - The Library Resource Project Grant at the Muhlenberg Hospital Library. PMID- 4142598 TI - Development of the self-instructional materials Learning Resources Center. PMID- 4142599 TI - [Demonstration of the presence of sialic acid on peripheral and intracytoplasmic membranes of the HeLa cell, by the colloidal iron histochemical reaction]. PMID- 4142600 TI - [Study of the viscosity of albumin, gamma globulin and fibrinogen solutions]. PMID- 4142601 TI - [Effect of small doses of the tumor specific antigen on further tumor growth]. PMID- 4142602 TI - [Metastatic carcinoma in the uterine mucosa]. PMID- 4142603 TI - [Results of palliative treatment of children with transposition of great vessels]. PMID- 4142604 TI - Cancer viruses. PMID- 4142605 TI - The gorilla karyotype: chromosome lengths and polymorphisms. PMID- 4142606 TI - [Subtypes of hepatitis-B-antigen (Australia antigen)]. PMID- 4142607 TI - [Cholestasis as ca clinical syndrome]. PMID- 4142608 TI - Effect of nercuric chloride on cellular morphology and acid phosphatase of tissue culture cells cultivated in suspension. PMID- 4142609 TI - Is there a factor in sera from cancer patients that inhibits lymphocyte response to phytohaemagglutinin? PMID- 4142610 TI - Feulgen hydrolysis of normal and leukemic blood cells. PMID- 4142611 TI - Blood serum vitamin A and beta-carotene in marasmic Egyptian infants. PMID- 4142612 TI - [Blocking of keratan sulphate engendered basophilia in aging human rib cartilage. I. Complete blocking of basophilia in the cartilage (author's transl)]. PMID- 4142613 TI - [Blocking of keratan sulphate engendered baslphilia in aging human rib cartilage. II. Selective blocking of keratan-sulphate engendered basophilia (author's transl)]. PMID- 4142614 TI - [Allergenic activity of automobile traffic exhaust gases]. PMID- 4142615 TI - Rapid phospholipid test for fetal pulmonary maturity. PMID- 4142616 TI - Protective effect of formate on GSH concentration and Heinz body formation: a preliminary model study. PMID- 4142617 TI - Homologous of the human A-B-O blood groups in apes and monkeys. PMID- 4142618 TI - The HL-A system genetics, (patho)physiology and clinical relevance. PMID- 4142619 TI - The role of the antibody in immunological cell triggering processes. PMID- 4142620 TI - [Recent biochemical findings in leukemia]. PMID- 4142621 TI - Functional properties of T and B lymphocytes in cell-mediated immunity. PMID- 4142622 TI - The clinical use of plasma fractions. PMID- 4142624 TI - Haemopoietic precursor cells in early human embryos: light microscopic pictures. PMID- 4142623 TI - Preparation of specific immunoglobulin for the prevention of hepatitis B. PMID- 4142625 TI - [Progress in small animal reproductive physiology, therapy of reproductive disorders, and pet population control]. PMID- 4142626 TI - Proceedings: Further studies on the third component of human complement: protein variants and C3 concentration in certain diseases. PMID- 4142627 TI - Proceedings: Criteria of viability of isolated liver cells. PMID- 4142628 TI - Proceedings: Inhibition of mouse leukemia virus RNA-dependent DNA polymerase by 2'-OH-substituted polynucleotides. PMID- 4142629 TI - Three-dimensional reconstruction of individual negatively stained yeast fatty acid synthetase molecules from tilt series in the electron microscope. PMID- 4142630 TI - Florometric histamine determination in canine plasma under normal conditions, following application of exogenous histamine, and during histamine release by haemaccel. PMID- 4142631 TI - Papovavirus structural polypeptides: comparison of human and rabbit papilloma viruses with simian virus 40. AB - A comparative study of the structural polypeptides of purified human papilloma virus, rabbit papilloma virus, and simian virus 40 (SV40) was performed by electrophoretic analysis on 10% polyacrylamide gels containing sodium dodecyl sulfate either by Coomassie blue staining or by electrophoresing purified virus preparations labeled with radioactive iodine. Analysis of human papilloma virus on stained gels revealed 6 bands with a major polypeptide of molecular weight 63,000 daltons comprising 60% of the virion protein. Analysis of rabbit papilloma virus on stained gels revealed 5 bands with a major polypeptide of molecular weight 60,000 daltons comprising 48% of the virion protein. Under conditions which yielded 6 polypeptides for SV40, in agreement with published data, 4 and 7 polypeptides were regularly detected in iodinated preparations of human and rabbit papilloma viruses, respectively. Isoelectrofocusing of iodinated virions revealed isoelectric points of pH 3.7 for SV40 and pH 4.0 for both rabbit and human papilloma viruses. PMID- 4142632 TI - The case for a family of reverse transcriptase viruses: Retraviridae. PMID- 4142633 TI - Antibody to the type 5 adenovirus hexon polypeptide: detection of nascent polypeptides in the cytoplasm of infected KB cells. AB - Antibody to type 5 adenovirus hexon polypeptides reacted with the isolated hexon polypeptide chanis (monomers) but not with the native multimeric hexon capsomers (trimers). Indirect immunofluorescence detected hexon polypeptides mainly in the cytoplasm of KB cells infected with types 2 and 5 adenoviruses. Cells infected with adenovirus mutants H5ts116 or H5ts115, which are defective in the production of immunologically detectable hexons, synthesized immunologically detectable hexon polypeptides at the nonpermissive temperature. PMID- 4142634 TI - On the origin of RNA tumor viruses. PMID- 4142635 TI - The caudate nucleus of the rat: cell types and the demonstration of a commissural system. PMID- 4142636 TI - Synthesis of the pentapeptide sequence 105-109 and smaller fragments of human encephalitogenic protein containing the arginine residue 107. PMID- 4142637 TI - Intermittent parasystole with concealed bigeminy. PMID- 4142638 TI - A review of lamination in area 17 of the visual cortex Macaca mulatta. AB - This paper develops a concordance of methods for designating laminae in the primate striate cortex. The classic notation schemes of Ramon y Cajal, Brodmann, and von Bonin and four recent modifications are described in words and photomicrographs. The recent trend toward adopting a lamination scheme that effects a division of cells into recognizable layers and at the same time reflects their connections is considered. Since a single, consistent plan for lamination of the visual cortex would facilitate communication among investigators, it is suggested that Brodmann's original scheme be followed as the most generally useful and applicable. PMID- 4142639 TI - Meynert cells in the primate visual cortex. AB - The solitary cells of Meynert are distinguished by their specific location in layer V of the striate cortex, very large size, argyrophilia, and the profusion of neurofilaments in their dendrites and perikarya. They occur with greater frequency in the macular region of the cortex, spaced a minimal distance of 110 mum apart, at a maximum density of about 8000/cm-2. In the perifoveal cortex, Meynert cells are spaced about 400 mum apart and packed at a density of approximately 625/cm-2. Each Meynert cell has an apical dendrite and many large basal dendrites. The perikaryon and primary segments of all dendrites are spine free; however, more distally a total of 36 000 spines are present, differentially disposed upon the dendritic surfaces. The basal dendrites bear over 77% of the spines on the Meynert cell, although they account for only 66% of the total length of the dendritic arborization. The first part of the apical dendrite is the most densely decorated with appendages, accounting for almost 10% of the spines on the whole dendritic tree. The apical dendrite becomes progressively less spiny as it passes through the superficial part of layers IV and III; less than 2.5% of the total number of spines of the Meynert cell project from this part of the apical dendrite. When the dendrite reaches layer II it bursts into an umbel of rapidly tapering branches. These are highly spinose, accounting for 8 13% of the cell's total, dispersed over only 23% of the linear dendritic length. It is suggested that this differential distribution of thorns can be correlated with the axonal inputs in the various cortical layers, and that the Meynert cell is designed to receive maximal information from layers I and II, and from layers V and VI, which are sources mainly of intracortical inputs. Thus the Meynert cell may be principally concerned with integrative information. In the perifoveal cortex, the basal dendrites of adjacent Meynert cells overlap considerably, and the apical terminal bouquet dendrites do not. In the macular cortex, because of the increased frequency of these neurons, both basaal and apical terminal dendritic fields overlap. A model is developed to illustrate these hypotheses. PMID- 4142640 TI - Histologic and histometric study of the effect of fluoride on the rat mandibular condyle. AB - The effect of fluoride on the rat mandibular condyle was studied histologically and histometrically. The condyles of the rats that received 50 ppm fluoride in the drinking water for 17 weeks did not differ in structure from those of the control rats fed tap water containing 1 ppm fluoride. However, the condyles of the rats given 100 ppm fluoride in the drinking water for the same period showed a significant increase in both the thickness of the cartilage layer (P smaller than 0.02) and the density of cancellous bone (P smaller than 0.01) when compared to the controls. The thickening of the cartilage layer was due to an increase in the number of hypertrophied chondrocytes. The trabeculae of cancellous bone were thicker and consequently the bone marrow spaces were extremely reduced. The trabeculae contained more calcified cartilage in their cores. PMID- 4142641 TI - Identification of fluorescent antibodies in periodontitis. PMID- 4142642 TI - Proceedings: Preliminary characterizaiton of the histamine releasing activity of cotton dust. PMID- 4142643 TI - The role of adaptive regulation in the pathophysiology of psychiatric disease. PMID- 4142644 TI - [Prostatic hypertrophy - lists of statistics pertinent to diagnosis]. PMID- 4142645 TI - [Labelled thyroid hormones in the diagnosis of thyrotoxicosis]. PMID- 4142646 TI - The staining of elastic tissue and related fibres in uterine blood vessels. PMID- 4142647 TI - A technique for thin methacrylate sections of bone marrow. PMID- 4142648 TI - Work simplification applied to Thyopac-3 and Thyopac-4 kits. PMID- 4142649 TI - [Polycentric structure of the centromere portions of the chromosomes of Ascaridia galli (Schrank, 1788)]. PMID- 4142651 TI - Migration-inhibitory effect of serum from patients with prostatic cancer. AB - Serum from patients with carcinoma of the prostate were observed to possess a factor(s) capable of inhibiting the migration of allogeneic leukocytes in the direct leukocyte migration test. Maximum inhibitory activity was obtained with those sera possessing an elevated level of an as yet unidentified factor(s) in the alpha2-globulin fraction of the serum of these patients. The presence of such a factor(s) may prevent interaction between leukocyte-inhibiting factor sensitive cells and tumour cells and emphasizes the role ofhumoral inhibitory or 'immunoregulatory' factors, such as alpha2-globulin, on immunologicresponses as blastogenesis and inhibition of leukocyte migration, as potential abrogators of mechanisms of host-resistance, e.g., immunologic surveillance. PMID- 4142650 TI - Biological effects of 5-azacytidine in eukaryotes. AB - 5-Azacytidine (NSC-102 816) was prepared synthetically and independently isolated from the culture filtrate of Streptoverticillium ladakanus. It is an s-triazine analogue of cytidine possessing a broad spectrum of biological effects. In mammalian tissueit is phosphorylated to 5-azacytidine 5-phosphates and incorporated into different species of RNAs and into DNA. 5-Azacytidine 5 monophosphate inhibits orotidine 5-phosphate decarboxylase blocking thus the de novo pyrimidine synthesis. Following the administration of 5-azacytidine a rapid breakdown of liver polyribosomes has been observed; furthermore, in different systems a profound inhibitory effect of the drug on the maturation of ribosomal RNA has been found. 5-Azacytidine interferes with different induced liver enzymes; in some cases their activity is elevated since the rate of enzyme degradation is decreased. The cytostatic effect of the drug is directed primarily against lymphatic leukemia although some recent reports indicate its action also against human solid tumours. Chemotherapy of leukemic mice by 5-azacytidine results simultaneously in the depressed synthesis of liver and spleen polyamines. 5-Azacytidine exhibits furthermutagenic, abortive, immunosuppressive, antimitotic, radioprotective and virostatic effects. The drug also affects DNA and protein synthesis in embryonic tissues, cells intissue culture, regenerating livers, in bacteria and phages. The changes associated with the emergence of resistance towards 5-azacytidine are associated with the decreased activity of uridine kinase in mouse leukemia cells. On the contrary, in adult rate livers5 azacytidine administration leads to the increased activity of this enzyme. Differentauthors have used 5-azacytidine as a tool for the study of biochemical mechanisms connected with a cell proliferation and division. PMID- 4142652 TI - Persistence and movement of BHC in a watershed, Mount Mitchell State Park, North Carolina--1967-72. PMID- 4142653 TI - Contribution of household dust to the human exposure to pesticides. PMID- 4142654 TI - [Scandinavian seminar: environmental pollution and heart and lung diseases]. PMID- 4142655 TI - Propranolol (Inderal) therapy in pre-operative care for diffuse toxic goiter. Preliminary report. PMID- 4142656 TI - Cytogenetical diagnosis of malignant pleural effusions. PMID- 4142657 TI - Fibre systems in sputum. PMID- 4142658 TI - Accelerated clearing and staining of teratologic specimens by heart and light. PMID- 4142659 TI - [Results of a 30 year use of synthetic thyroid antagonists]. PMID- 4142660 TI - [Measure of capillary permeability during histamine liberation. Effect of disodium cromoglycate]. PMID- 4142661 TI - Further observations on atypical band keratopathy in glaucoma patients. PMID- 4142662 TI - A clinicopathologic study of a peculiar foveomacular dystrophy. PMID- 4142663 TI - Prostatic disease in the dog. PMID- 4142664 TI - [Acaricidic and toxic properties of dursban, sevin and chlorophos]. PMID- 4142665 TI - [The effectiveness of gamma globulin prevention in families with incubated infectious hepatitis screened by enzyme tests]. PMID- 4142666 TI - [Principles of the effect of cytostatics]. PMID- 4142667 TI - [Current concepts on the pharmacologic mode of action of the antirheumatic agents]. PMID- 4142668 TI - [Quantitative determination of blood proteins using 2-dimensional immunolectrophoresis]. PMID- 4142669 TI - Histological components of tibial fracture callus in growing osteopenic rats. PMID- 4142670 TI - Factors affecting prognosis of endometrial carcinoma. PMID- 4142671 TI - [Contribution of immunofluorescence to the diagnosis of helminthiasis]. PMID- 4142672 TI - [Effects of L-Dopa on gastric endocrine cells at several stages of rabbit ontogenesis (author's transl)]. PMID- 4142673 TI - Absence of effect of endotoxin on the isolated ileum of the guinea-pig. PMID- 4142674 TI - A theory on the action of bacterial endotoxins. PMID- 4142675 TI - The liver-pathogenic role of spleen suspension of rats treated with carbon tetrachloride. PMID- 4142676 TI - Studies on alpha2-macroglobulins. PMID- 4142677 TI - Studies on connections between quality of plasma and impurities of gamma globulin and albumin preparations. PMID- 4142678 TI - Freeze-dried virus antigens and FITC-conjugated immune sera for virus diagnostic purposes. PMID- 4142679 TI - Present state and perspectives of the farctionation of human plasma, serum and placenta. PMID- 4142680 TI - A study of immunospecifically isolated tetanus antibodies. PMID- 4142681 TI - Interaction between lysozyme and some lactoferrin complex in human milk. PMID- 4142682 TI - Reoxidation of reduced hen egg-white lysozyme. (II). Circular dichroism and fluorescence emission analysis. PMID- 4142683 TI - Modification of tyrosine residues in human alpha-lactalbumin: effect upon the lactose-synthase specifier activity. PMID- 4142684 TI - [Fumarase in chickens. V. Effect of substrate and hydrogen ion concentrations on enzymatic activity]. PMID- 4142685 TI - [Fumarase in chickens. VI. Effect of inhibitors on enzyme activity]. PMID- 4142686 TI - [Fumarase in chickens. VII. Effect of detergents on enzymatic activity]. PMID- 4142687 TI - Chlorpromazine and phospholipid metabolism in the rat hypothalamus. Effect of pretreatment with piracetam. PMID- 4142688 TI - [Selective pressure on cytochrome c. Evidence for correlations between amino acids separated by n peptide bonds]. PMID- 4142689 TI - Chromatographic equilibrium of human alpha-lactalbumin. PMID- 4142690 TI - [Application of calculation of coefficients of activity to the study of proteins and detergents]. PMID- 4142691 TI - [Isolation of plasma membrane from rat pancreas]. PMID- 4142692 TI - Uptake and intracellular localization of kanamycin and gentamycin in the lysosomes of cultured fibroblasts. PMID- 4142693 TI - Mutation sites in the coat-protein gene of bacteriophage MS2. PMID- 4142694 TI - [Calorimetric study of the attachment of inositol hexaphosphate on pigeon hemoglobin]. PMID- 4142695 TI - [Phospholipid repair and deficiency in septation in Excherichia coli K 12]. PMID- 4142696 TI - The synthesis of human placental lactogen by human placental ribosomes. PMID- 4142697 TI - Fluorimetric and nuclear magnetic resonance binding studies of a fluorescent dye interacting with alpha-lactalbumin and lysozyme. PMID- 4142698 TI - [Homage to Albert Claude and Christian de Duve, Nobel Prize laureates in medicine and physiology, 1974]. PMID- 4142699 TI - Salinity-induced changes in the alanine and aspartic aminotransferase activity in three marine bivalve molluscs. PMID- 4142700 TI - [Chemical characteristics and pharmalogical characteristics of several alkaloid extracts of Strychnos usambarensis]. PMID- 4142701 TI - Eye movements elicited by electrical stimulation of the pontine reticular substance. PMID- 4142702 TI - Inhibition of ciliary movements by Ni-2+ions in triton-extracted models of Paramecium caudatum. PMID- 4142703 TI - The effect of chelation of calcium ions in cerebrospinal fluid on the osmotic thirst in dogs. PMID- 4142704 TI - Protein nutrition of Tenebrio molitor L. XVIII. Growth of larvae of race F fed protein blends of cereals and legumes. PMID- 4142705 TI - The cardiac pressoreceptors and the heart enlargement. PMID- 4142706 TI - The estimation of contractile element velocity during the isovolumic period: alterations by cardiac output and contractile state. PMID- 4142707 TI - Catecholamines in blood during direct stimulation of the hypothalamus in dogs. PMID- 4142709 TI - The regeneration with cysteine of gastropod haemocyanin mediated by hydrogen peroxide. PMID- 4142708 TI - Distribution of some phosphohydrolases in glomerular and tubular fractions isolated from rabbit kidney. PMID- 4142710 TI - Effects of osmolality on hypoxic myocardium. PMID- 4142711 TI - Results obtained with two different perfusion chambers for double sucrose gap on voltage clamp currents in frog atrial trabeculae. PMID- 4142712 TI - Decision component parameters. PMID- 4142713 TI - The rate of contraction of some striated muscles in Perodicticus potto. PMID- 4142714 TI - [Cystamine and blood depletion in dog kidneys perfused with preserved blood]. PMID- 4142715 TI - Effect of the ionic composition of the extracellular fluid on energy metabolism of the liver in hypothermic anoxia. PMID- 4142716 TI - [Urinary elimination of tryptophan in dogs]. PMID- 4142717 TI - The precursors of milk proteins. PMID- 4142718 TI - [Ribonuclease activity in the pancreas]. PMID- 4142719 TI - Messenger RNA levels from the bipolar arginine ECBH operon of Escherichia coli. PMID- 4142720 TI - Characterization of free reverse transcriptase in the blood plasma of leukemic chicken. PMID- 4142721 TI - [Effects of carbamylcholine on the lipid metabolism of rat exocrine pancreas]. PMID- 4142722 TI - Physico-chemical characterization of ribosomes isolated from dormant embryos and nauplii of Artemia salina. PMID- 4142723 TI - Mutant selection in the control region of the arg ECBH bipolar operon of Escherichia coli. PMID- 4142724 TI - Virginiamycin, an inhibitor of protein synthesis: binding of the factor S to the 50 S ribosomal subunit. PMID- 4142725 TI - Alpha-mannosidase in the hen's egg yolk. PMID- 4142726 TI - Cholinesterase activities in the hen's egg. PMID- 4142727 TI - [Selective pressure on cytochrome c. II. Evidence for notable substitutions in the nucleotides]. PMID- 4142728 TI - Toxicity of quartz and kaolin towards membranes: effect of lysozyme. PMID- 4142729 TI - [Sensitivity of pancreatic adenyl cyclase to gastrointestinal hormones]. PMID- 4142730 TI - Synthesis of a poly(A)-segment, covalently linked to the 3'-end of bacteriophage MS2 RNA. PMID- 4142731 TI - Influence of alloxan-diabetes and insulin on liver protein kinase. PMID- 4142732 TI - [Light chain myosin of carp white muscle]. PMID- 4142733 TI - Partial conservation and transfer to progeny of bacillus subtilis bacteriophage 2C DNA. PMID- 4142734 TI - On the substrate specificity of phosphorylase a phosphatase. PMID- 4142735 TI - Requirement of iron in the induction process of the cyanide-insensitive respiration in Endomycopsis lipolytica. PMID- 4142736 TI - [Comparative study of the myofibrils of white, cardiac and red muscles of carp, using polyacrylamide gel electrophoresis]. PMID- 4142737 TI - Activation of liver glycogen phosphorylase by vasopressin. PMID- 4142738 TI - [Stoichiometric binding of concanavalin A to hydrolases of human serum and liver]. PMID- 4142739 TI - [Beta-lactamases of resistance factors to antibiotics belonging to classes of known compatability to the original organism]. PMID- 4142740 TI - Synthesis in vitro of Artemia salina proteins in an homologous cell-free system. PMID- 4142741 TI - Cyclic nucleotides and growth regulation in fibroblasts. PMID- 4142742 TI - Reoxidation of reduced hen egg-white lysozyme. (I). Chromatographic and enzymic properties of the reoxidation products. PMID- 4142743 TI - [Determination of the immunological effects of immune serum and gammaglobulin on trophozoites of E. histolytica]. PMID- 4142744 TI - [Determination of alpha-1-fetoprotein in the serum of children with invasive amebiasis]. PMID- 4142745 TI - The female child as a surrogate object. PMID- 4142746 TI - Youth and pornography in social context. PMID- 4142747 TI - [Control of the source of air pollution]. PMID- 4142748 TI - [Keratitis of labrador. Clinical, histochemical and ultrastructural study of 3 cases]. PMID- 4142749 TI - Completion of the analysis of the primary structure of the variable domain of a homogeneous rabbit antibody to type III pneumococcal polysaccharide. AB - The amino acid sequence between residues 70 and 116 of the V (variable) region of the H (heavy) chain derived from rabbit antibody BS-5, specific for type III pneumococcal polysaccharide, was determined. The sequence of this section of the H chain which includes the hypervariable residues 94 to about 112 was unique, although minor variant sequences present in the H chain preparation would not have been detected by the techniques used in this work. Taken together with the known sequences of the N-terminal 69 residues of H chain BS-5 (Jaton & Braun, 1972) and of the V region of the light chain (Jaton, 1974b), the data establish the complete sequence of the V domain of a rabbit immunoglobulin G. The V region of H chain BS-5 is compared with the basic sequences of the three human V region subgroups known to date, with one mouse H chain, and with guinea-pig pooled H chains. Even though chains from guinea pig and mouse clearly belong to the subgroup III of variability (V(HIII)), rabbit H chain BS-5 (allotypic variant a(1)) appears more closely related to the subgroup V(HII) than to the subgroups V(HIII) or V(HI). The homology between V(L) and V(H) regions of antibody BS-5 (28%) is not greater than that observed between the V(H) region of antibody BS-5 and the V(L) regions of different rabbit antibodies. PMID- 4142750 TI - Immunological evidence to show that the N-acetylglucosaminidase and N acetylgalactosaminidase activities of Dictyostelium discoideum reside in the same protein molecule. AB - Antibodies were produced against purified beta-N-acetylhexosaminidase from Dictyostelium discoideum. Ouchterlony tests produced a single precipitin band with both beta-N-acetylglucosaminidase and beta-N-acetylgalactosaminidase activities. Both activities were co-precipitated in exactly the same proportions in quantitative immunoprecipitation reactions. We conclude that one enzyme protein catalyses the hydrolysis of both N-acetylglucosaminides and N acetylgalactosaminides. PMID- 4142751 TI - [The behavior of the mast cells of the mesentery in the presence of histamine liberators in rats resistant to traumatic shock]. PMID- 4142752 TI - The importance of seminal plasma for human sperm motility. PMID- 4142753 TI - [Mucopolysaccharides of the chamber angle and ocular pressure]. PMID- 4142754 TI - [Morphology and histochemistry of the jejunal mucosa in patients with lactase deficiency]. PMID- 4142755 TI - [Chronic hepatitis]. PMID- 4142756 TI - [Medullary carcinoma of the thyroid gland]. PMID- 4142757 TI - Sensitivity to mycobacterial antigens. AB - In a study carried out in 1971, each of 3 030 persons was tested simultaneously with tuberculin RT 23 and two other PPD sensitins-PPD-S and PPD-A, PPD-B and PPD Y, or PPD-G and PPD-F. Of the 2 558 persons whose reactions were read, 20.2% had previously been vaccinated with BCG and 79.8% were unvaccinated. RT 23 and PPD-S produced almost identical mean indurations. Both elicited much higher reactions than the sensitins prepared from atypical mycobacteria. Correlation of the sizes of induration obtained with RT 23 and with the other sensitins showed that low grade sensitivity was due to cross-reactions to human tuberculous infection and that in no case did an "atypical" sensitin produce an induration of wider diameter than RT 23 did. It is concluded that nonspecific tuberculin sensitivity was not demonstrated in this study. PMID- 4142758 TI - [Surgery of rectal carcinoma from the current point of view]. PMID- 4142759 TI - Redistribution of immunoglobulin determinants on human lymphocytes in lymphoproliferative disorders. PMID- 4142760 TI - [Spectrofluometric determination of dihydrostreptomycin in drug preparations]. PMID- 4142761 TI - [Study of the interaction of scopolamine hydrobromide with serum proteins]. PMID- 4142762 TI - [Technology of soliutizon tablets by means of direct pressing]. PMID- 4142763 TI - [Study of the electron absorption spectra and the antithyroid activity of some 1,3-thiazine derivatives]. PMID- 4142764 TI - The epididymis as a possible site for control of fertility in the male. PMID- 4142765 TI - Studies on alpha-2-macroblobulins. PMID- 4142766 TI - Purification of antitetanus human IgG by immunoadsorption. PMID- 4142767 TI - Impurities in gammaglobulin and albumin preparations: influence of the source material. PMID- 4142768 TI - [Preparation of human albumin from hemolysed blood from frozen placental extracts. I. Technique for preparation and quality of the product]. PMID- 4142769 TI - Immunological studies on the presence of placental material in retroplacental blood. PMID- 4142770 TI - Hepatitis B: Au/HA-antigen during production of human albumin and gammaglobulin. PMID- 4142771 TI - Transmission of viral hepatitis, type B, by plasma derivatives. PMID- 4142772 TI - Standardization of human antivaccinia immunoglobulins and elaboration of a national substandard preparation. PMID- 4142773 TI - [Absence of prostaglandins in serum albumins and gammaglobulins from placental blood]. PMID- 4142774 TI - Preparation of anti-Rho (D) specific immunoglobulins according to WHO recommendation. PMID- 4142775 TI - [Acrylamide gel electrophoresis and gel filtration as methods of analysis for blood protein derivatives]. PMID- 4142776 TI - Content of IgG, IgA and IgM immunoglobulins in international units in normal and IgA-enriched gammaglobulins. PMID- 4142777 TI - [Standardization of specific gammaglobulins of human origin. Determination of a gammaglobulin against rabies]. PMID- 4142778 TI - [Cytochemistry of acid mucopolysaccharides of the granulocytic series in chronic myelocytic leukemia (author's transl)]. PMID- 4142779 TI - Isolation, purification and biological properties of horse precipitating and non precipitating antibodies. PMID- 4142780 TI - An antibody sandwich method for the radioimmunoassay of human alpha-fetoprotein. PMID- 4142781 TI - Immunoenzymology of L-asparaginase from the BCG strain of Mycobacterium bovis. PMID- 4142782 TI - The behaviour of antigenically related influenza viruses of differing virulence on disulphide-linked immunosorbents. PMID- 4142783 TI - Opsonic properties of human serum alpha-2 hs glycoprotein. PMID- 4142784 TI - Membrane antigenic changes associated with PHA transformation of mouse spleen cells in vitro. PMID- 4142785 TI - The thymic suppre-sor cell. II. Metabolic requirements of suppressor activity. PMID- 4142786 TI - Isolation of a primate type-C virus from a lymphomatous baboon. AB - A type-C RNA virus has been isolated from various tissues of a lymphomatous baboon (sp. P hamadryas). Virus isolations were made by co-cultivating baboon cells from the inguinal and mesenteric lymph nodes, testes, kidneys and spleen with cells of canine or human origin. The isolated virus grew in canine, bat, rhesus, and human cells but not in cells of mouse, rat, cat or rabbit origin. The baboon isolate resemble a type-C virus when infected cells were examined by thin section in the electron microscope. In addition, the virus was capable of providing helper function by rescuing and transmitting the Moloney and Kirsten sarcoma virus genome from non-productively transformed cells. Antibody directed against the RD114 virus reverse transcriptase was very effective in inhibiting the baboon virus polymerase while while anti-mouse and woolly type-C virus polymerase antibodies had no significant inhibitory activity. Further analysis by immunodiffusion and competitive radioimmune assay revealed a close immunological relationship between this virus, RD114 and another type-C virus isolated from the placenta of a different species of baboon. Finally, three different classes of interspecies antigenic determinants have been demonstrated in mammalian type-C virus isolated from the placenta of a different species of baboon. Finally, three different classes of interspecies antigenic determinants have been demonstrated in mammalian type-C viruses. PMID- 4142787 TI - Distribution of concanavalin a receptors on normal rat liver cells and zajdela ascites hepatoma cells. AB - The distribution of Concanavalin A receptors in cultures of normal rat liver cells and of Zajdela ascites hepatoma cells of the rat was investigated by the Con A-po technique (Bernhard and Avrameas, 1971). Con A-po labelling of the cell surface showed a patchy distribution of Concanavalin A receptors in ascites hepatoma cells, whereas continuous Con A-po labelling was seen at the surface of normal rat liver cells. The different distribution of Concanavalin A receptors was caused by rapid internalization of Con A-po labelled material and not by a simple rearrangement of the receptors. The significance of this process is discussed with respect to Concanavalin A receptor mobility and membrane stability after cell transformation. PMID- 4142788 TI - Actinomycin-D-resistant in vitro mouse cell line derived from a methylcholanthrene-induced sarcoma: decrease of malignancy and antigenic characteristics. AB - The tumorigenic EPO clonal cell line, derived from a methylcholanthrene-induced murine sarcoma, was exposed to increasing concentrations of actinomycin D and gave rise to a subline, resistant to 0.02 mug of actinomycin D per ml of medium, which was designated EPO/ADj. Drug resistance was accompained by a striking decrease of tumorigenic capacity as determined by the tumor take incidence and tumor growth rate in syngeneic C57BL/6 mice (normal and X-irradiated), as well as by tumor take incidence in the cheek pouch of cortisone-treated weanling Syrian hamsters. One of the tumors obtained after inoculation of EPO/ADj cells into syngeneic mice was reexplanted in culture and developed as the EPO/ADj/T subline. It was found to be relatively resistant to actinomycin D as compared to the parental EPO cells. The morphology of cells changed with actinomycin-D resistance: EPO/ADj cells were more spread and flattened and less overlapping than the original fibroblast-like EPO cells. EPO/ADj/T cells, however, had an aspect similar to that of EPO cells. No major differences were seen between the karyotypes of EPO, EPO/ADj and EPO/ADj/T cells. Tumor-specific antigen(s), characteristic of drug-sensitive, parental EPO line, was expressed in the resistant EPO/ADj and EPO/ADj/T lines, as shown by: (a) transplantation resistance to challenge with EPO cells in syngeneic mice pretreated with EPO/ADj cells; and (b) cross-reactivity in indirect immunofluorescence tests performed with sera from syngeneic animals hyperimmunized with EPO or EPO/ADj cells. Furthermore, an additional surface antigen(s), absent from EPO cells, was demonstrated in EPO/ADj and EPO/ADj/T cells by means of immunofluorescence tests performed with specific anti-EPO/ADj syngeneic sera previously absorbed on EPO or EPO/ADj cells. PMID- 4142789 TI - Activity of uridine kinase in different lines of AKR leukemic mice and its relation to chemotherapy with 5-azacytidine. AB - The sensitivity of different wild-type and 5-azacytidine-resistant lines of AKR leukemic mice to 5-azacytidine varies in relation to the activity of uridine kinase isolated from corresponding leukemic livers. The enhancement of liver uridine kinase activity observed in leukemic mice following the administration of a single dose of 5-azacytidine is accounted for by the presence of hepatocytes in infiltrated leukemic livers. The optimal schedule for the treatment of AKR leukemic mice with 5-azacytidine requires equally divided doses administered daily and not an initial high dose followed by low doses. PMID- 4142790 TI - The detailed chromosome constituiton of a benzpyrene-induced sarcoma. A tentative model for G-band analysis in solid tumors. PMID- 4142791 TI - The vanding pattern in philadelphia-chromosome negative chronic myeloid leukemia. PMID- 4142792 TI - Cytogentical studies with G-band technique of established cell lines of human malignant glomas. PMID- 4142793 TI - An experimental demonstration of discriminated (nongeneralized) imitation. PMID- 4142794 TI - Clinical trial of bleomycin on female genital cancer: a preliminary report. PMID- 4142795 TI - The combined therapy of carcinoma of the tongue by using bleomycin and radiation. PMID- 4142796 TI - Retention mucoceles of the oral mucosa. PMID- 4142797 TI - Some physicochemical and pharmacological properties of morphine-2,3-quinone, the morphine metabolite in the rat brain. PMID- 4142798 TI - Studies on lividomycin. I. In vitro antibacterial activities of LVDM against clinical isolates of Mycobacterium tuberculosis. PMID- 4142799 TI - [Clinicophathological studies of alpha-fetoprotein. (1). Clinical and experimental studies of various non-malignant liver diseases]. PMID- 4142800 TI - [Studies on alpha fetoprotein. 2. Investigation of the factors influencing alpha fetoprotein production in primary hepatocellular carcinoma]. PMID- 4142801 TI - Two new types of C-band variants in human chromosome (6ph+ and 12ph+). PMID- 4142802 TI - New weapon in war on lice; Stafford-Miller launch Quellada in Australia. PMID- 4142803 TI - [Apropos of a case of acquired ureterocele]. PMID- 4142804 TI - [Action of the combination of hypothalamic phospholipids and megestrol acetate (IP 11) in prostatic hypertrophy. Results of a controlled clinical trial]. PMID- 4142806 TI - [Practical application of photostimulation of development to cultivation of industrial strains of microorganisms]. PMID- 4142805 TI - [Precipitation of lipoproteins by protamine after heparin induced lipolysis]. PMID- 4142807 TI - [Growth and development of the producer of gramicidin S in different cultivation conditions]. PMID- 4142808 TI - Anemia from sleep deprivation with anticoagulants in rats with enhancement by PCPA. PMID- 4142809 TI - [Waldenstrom's disease (post-epiphysiolytic necrosis of the articular cartilage)]. PMID- 4142810 TI - [The wild child. Homage to Jean Itard]. PMID- 4142811 TI - [Research in vitro on the action of gamma globulins on the mechanism of formation of plasma thromboplastin]. PMID- 4142812 TI - [The determination of the Au/SH- antigens: a methods and reagents comparison]. PMID- 4142813 TI - Estrogen receptor: a valid test for selection of breast cancer patients for endocrine ablation. PMID- 4142814 TI - Bleomycin 111-I scanning: a new technique for detecting subclinical metastatic cancer. PMID- 4142815 TI - [The effectiveness of antidiuretic hormone in the presence of inhibited protein synthesis in different subcellular structures]. PMID- 4142816 TI - [Mouse rosette forming cells in transplantation immunity]. PMID- 4142817 TI - [A comparison of the karyotypes of 2 species of susliks following differential Giemsa staining of the chromosomes]. PMID- 4142818 TI - [Lengthwise differentiation of human chromosomes and the problem of their identification. IV. Group C chromosomes]. PMID- 4142819 TI - [Effect of thyroid hormones, thyrostatics and thyroidectomy on the content of protein-bound iodine and fucose in the blood serum of rats]. PMID- 4142820 TI - [Isolation of an immune complex from a high-molecular serum protein fraction from cancer patients]. PMID- 4142821 TI - Efferent projections of the subthalamic nucleus. PMID- 4142822 TI - [alpha1-Foetoprotein: II, isolation and crystallization from a primary liver cell carcinoma (author's translation)]. PMID- 4142823 TI - [Free thyroxin in serum (equilibrium dialysis with native and diluted serum) (author's transl)]. PMID- 4142824 TI - Gel isoelectric focusing of cerebrospinal fluid proteins: a potential diagnostic tool. PMID- 4142826 TI - [Quantitative determination of serum proteins following their separation by disc electrophoresis in polyacrylamide gel (author's transl)]. PMID- 4142825 TI - [Studies on the normal concentration range of total protein and the total protein fractions of the cerebrospinal fluid by electrophoresis on cellulose acetate (author's transl)]. PMID- 4142827 TI - [Comparative characteristics of endemic foci of scleroma in the world]. PMID- 4142828 TI - [Pharmacologic properties of fluorinated phenylethanolamine]. PMID- 4142829 TI - [Changes of erythropoiesis in acute leukoses]. PMID- 4142830 TI - [Treadmill-ergometry in cardiological diagnosis]. PMID- 4142831 TI - [New technics in the study of the morphology of chitinous formations of Acari]. PMID- 4142832 TI - Gastric antisecretory and antiulcer agents. PMID- 4142833 TI - Effect of a histamine H-2-receptor antagonist on immunologically induced mediator release in vitro. PMID- 4142834 TI - Studies of the mechanism of histamine release from lung tissue in vitro by cotton dust extracts. PMID- 4142835 TI - Histamine release from mast cells by compound 48/80. The membrane action of zinc. PMID- 4142836 TI - Problems in the assay of histamine release by gelatin: o-Phthaldialdehyde-induced fluorescence, inhibition of histamine methyltransferase and H-1-receptor antagonism by Haemaccel. PMID- 4142837 TI - Evaluation of histamine elimination curves in plasma and whole blood of several circulatory regions: a method for studying kinetics of histamine release in the whole animal. PMID- 4142838 TI - The mast cell and disodium cromoglycate in immediate type reactions. PMID- 4142839 TI - The smooth endoplasmic reticulum and the retrograde and fast orthograde transport of horseradish peroxidase in the nigro-striato-nigral loop. PMID- 4142840 TI - [Mouse teratocarcinoma: studies of antigens at the surface of multipotential cells (author's transl)]. PMID- 4142841 TI - [Comparison of two serotyping methods for "Staphylococcus aureus": Pillet's method and OEding-Haukenes' method. Application tto type-strains and wild strains (author's transl)]. PMID- 4142842 TI - [Clinical uses of qualitative changes in the amniotic fluid in detection of fetal distress (bibliographic review)]. PMID- 4142843 TI - [Hepatic, arterial embolization in patients with malignant liver tumours (author's transl)]. PMID- 4142844 TI - Plasma GH levels after L-Dopa in prepuberal normal children and in pituitary dwarfs. PMID- 4142845 TI - Pituitary secretory reserve in patients with amenorrhea associated with galactorrhea. PMID- 4142846 TI - [Testosterone and oestradiol17 beta production rates in a patient suffering fromhypertrophy of the prostate (author's transl)]. PMID- 4142847 TI - [Proceedings: Reactive thyrotropic adenomes. 2 surgically confirmed cases]. PMID- 4142848 TI - [Proceedings: Effect of triiodothyroacetic acid on the hypothalamo-hypophyseal thyroidal axis]. PMID- 4142850 TI - Chemotaxis of eosinophil leukocytes in relation to immediate-type hypersensitivity and the complement system. PMID- 4142849 TI - [Proceedings: Effect of triiodothyroacetic acid on the hypothalamic-pituitary thyroid axis (author's transl)]. PMID- 4142851 TI - Enzyme activation and the mechanism of neutrophil chemotaxis. PMID- 4142852 TI - [The effect of rifampicin on several indices of lipid and protein metabolism, leukocyte count, blood picture and phagocytic activity of neutrophils in animals]. PMID- 4142853 TI - [Actinomycin D-o]. PMID- 4142854 TI - [The influence of amino acids on actinomycin biosynthesis by a suspension of Act. sp. 2 mycelia]. PMID- 4142855 TI - [The effect of aurantin on several indices of the mitotic regime of transplantable cultures of human amniotic cells (line A-1)]. PMID- 4142856 TI - [Isomers of actinomycin Au6 (actinoleucine)]. PMID- 4142857 TI - [The effect of nuclear proteins on the interaction of aurantin with DNA]. PMID- 4142858 TI - Golgi impregnation study on the liquor-contacting cells bordering the preoptic recess in amphibians. PMID- 4142859 TI - [Identification of the elements of the basophilic granulocytes by the use of methylene blue]. PMID- 4142860 TI - [Renal histo-morphological changes in guinea pigs kept in urban rubbish dumps]. PMID- 4142861 TI - [Current data on the cytological classification of acute leukemias]. PMID- 4142862 TI - [Effect of a uniform magnetic field on leukocytes. Study of the leukocyte migration test in lepers]. PMID- 4142863 TI - [Leptospiroses in tropical medicine. Epidemiology and diagnosis on Reunion Island and in French Polynesia (Tahiti)]. PMID- 4142864 TI - [Venereal syphilis is not of American origin]. PMID- 4142865 TI - [Importance of the amount of alpha-1-fetoprotein in obstetrics]. PMID- 4142866 TI - [Trypanosoma brucei gambiense. Antigenic study. II. Immunogenic fractions. Partial results]. PMID- 4142867 TI - [First case of confirmed leptospirosis in Mali]. PMID- 4142869 TI - [A protocerebral neurosecretory center acting on water balance in the larva of Aeshna cyanea Mull. (Insecta, Odonata)]. PMID- 4142868 TI - [Localization of calcium in the Golgi apparatus of adenohyphyseal cells of the rat and mouse using potassium pyro-antimoniate]. PMID- 4142870 TI - [Electrotherapy of algodystrophies]. PMID- 4142871 TI - Demonstration of repair of potentially lethal damage in plateau phase cells of Ehrlich ascites tumor after exposure to bleomycin. PMID- 4142872 TI - Investigation of the ovarian chromaffin tissue in the fresh water teleost fishes. PMID- 4142873 TI - [Combined action the human body of a mixture of the basic components of motor vehicle exhaust gases (carbon monoxide, nitrogen dioxide, formaldehyde and hexane)]. PMID- 4142874 TI - [Utilization of infrared spectroscopy for determining environmental contaminants]. PMID- 4142875 TI - Leukocyte osmotic fragility in patients with hematologic neoplasms and cancer. PMID- 4142876 TI - [Acute promyelocytic leukemia: clinical, cytochemical and ultrastructural aspects]. PMID- 4142877 TI - [Surgical treatment of transposition of great vessels]. PMID- 4142878 TI - Studies on passive immunity in the foal. III. The characterization and significance of neonatal proteinuria. PMID- 4142879 TI - Haematological and plasma protein changes in sheep experimentally infected with Corynebacterium pseudotuberculosis. PMID- 4142880 TI - [Comparison of the antigenic properties of a protein polymerized by the types of spiral and cylindrical symmetry]. PMID- 4142881 TI - Economic impact of mass production of alternative low emission automotive power systems. PMID- 4142882 TI - [Amnesic Aphasia. Clinical picture and consideration of the neurolinguistic structure (author's transl)]. PMID- 4142883 TI - Afferent influences upon human genioglossal muscle. PMID- 4142884 TI - Biochemical findings in multiple sclerosis I. A detailed study of the plasma lipid fractions of 484 multiple sclerosis patients compared with 152 other neurological diseases. PMID- 4142885 TI - Double ring formation in single radial immunodiffusion for kappa chains in multiple sclerosis cerebrospinal fluid. PMID- 4142886 TI - [Haematomyelia with paraplegia following coarctation of the aorta (author's transl)]. PMID- 4142887 TI - [The value of a dichotic discrimination test in the diagnosis of cerebral lesions (author's transl)]. PMID- 4142888 TI - A new polygenic disturbance: cystinuria, leucinuria and spinal muscular atrophy. PMID- 4142889 TI - Changes of gamma globulins in serum and cerebrospinal fluid of patients with subacute sclerosing panencephalitis. PMID- 4142891 TI - A general synthesis of N-glycosides. V. Synthesis of 5-azacytidines. PMID- 4142890 TI - Oxytalan connective tissue fibers: a review. AB - Oxytalan connective tissue fibers are a separate and distinct fiber type. Although current histochemical methods cannot distinguish pre-elastic from oxytalan fibers, the two fiber types are readily distinguished by electron microscopy. Oxytalan fibers are found in periodontal membranes of all teeth of man, monkeys, rats, guinea pigs and mice. Increased numbers and size of oxytalan fibers are observed in periodontal membranes of teeth subjected to increased stress, such as those used for bridge abutments. Edwards (1968) observed increased size and number of oxytalan fibers in periodontal membranes of dog incisors subjected to orthodontic forces. Some oxytalan fibers serve to support the blood and lymphatic vessels leading to the teeth. Oxytalan fibers appear to have a protein component and a stainable component digestible with beta glucuronidase after peracetic acid digestion. Oxytalan fibers develop in repair tissues of the periodontal membrane. Although oxytalan fibers probably develop in relation to tumors developed from dental tissues, electron microscopy must be employed to distinguish oxytalan from developing elastic tissues inasmuch as histochemical methods are inadequate. PMID- 4142892 TI - Editorial: the medical recording service foundation. PMID- 4142893 TI - [Histamine liberation in the dog through trypsin and kallikrein; problem of physiopathological importance in acute pancreatits]. PMID- 4142894 TI - [Animal experimental studies on free autologous muscle trasplantation]. PMID- 4142895 TI - [Drainage of the thoracic duct as a surgical contribution to immunosuppressive therapy]. PMID- 4142896 TI - [Use of antimacrophage-serum for the demonstration of cytogenetic relations]. PMID- 4142897 TI - [Productive gingival and palatial lesions in Bourneville's syndrome. Histopathological and histochemical aspects]. PMID- 4142898 TI - [Lindane metabolism. Degradation of lindane by mold cultures. Unconjugated metabolites]. PMID- 4142899 TI - [Determination of DDT- and BHC-residue tolerances in milk fat]. PMID- 4142900 TI - Expanded roles for nurses--the view of a physician. PMID- 4142901 TI - [Cognition disorders in mentally retarded]. PMID- 4142902 TI - [HL-A and Basedow's disease]. PMID- 4142903 TI - [Content of various serum protein fractions in the mothers, the newborn and infants in the first months of life. The relation of these indices to the antibody level]. PMID- 4142904 TI - [Effect of inhibitors of protein and nucleic acid synthesis on the shape of the nucleoid of Escherichia coli]. PMID- 4142905 TI - [Significance of the left axis deviation in the electrocardiogram]. PMID- 4142906 TI - [Current status of the usability of corium as reconstruction material in heart valve autoplasty]. PMID- 4142907 TI - Epithelial cell structure and function following massive intestines resection. PMID- 4142908 TI - [Experimental studies on the relation between wound healing and local use of vitamin A acid]. PMID- 4142909 TI - [The influence of vitamin K on clotting factors and enzymes with short half lives in rat liver (author's transl)]. PMID- 4142910 TI - Useful buffer and gel systems for polyacrylamide gel electrophoresis. PMID- 4142911 TI - [Lipid metabolism during a dietary magnesium deficiency. Studies on artherosclerosis induced by magnesium deficiency (author's transl)]. PMID- 4142912 TI - [Peripheral circulation in traumatic para- and tetraplegia (author's transl)]. PMID- 4142913 TI - [Synovectomy and myotomy at the hip-joint in rheumatoid arthritis (author's transl)]. PMID- 4142914 TI - Effect of prednisolone on callus formation. PMID- 4142915 TI - The effects of juvenile hormone on the prothoracic glands in Galleria mellonella L. I. Morphology of the glands in the course of the postembryonic development. PMID- 4142916 TI - [Treatment of extrasystoles using a new oral anti-arrhythmic agent Aprindine]. PMID- 4142917 TI - [Pathogenesis of thyrotoxic crisis]. PMID- 4142918 TI - Irradiation of brain metastases. AB - A series of 124 patients with intracranial metastases, treated by irradiation, has been reviewed, retrospectively and prospectively, and the results are reported. Worthwhile palliation was obtained in 79 (63%) of the total number of patients with functional improvement documented in 52 (41%). The uncorrected mean survival was 4.7 months. The addition of surgery to irradiation did not improve results significantly in this series. Therefore, surgical removal should be performed on special indications such as rapidly progressing increase in intracranial pressure unresponsive to steroids or shunt, or if the etiology of the intracranial lesion is uncertain. PMID- 4142919 TI - A polarization microscopic study of granular pneumocytes and alveolar interface in rat lung. PMID- 4142920 TI - The C-cells of the rat thyroid in different stages of postnatal ontogenesis. PMID- 4142921 TI - The correlations of positive skin tests with inhalants in asthma of probable allergic origin. PMID- 4142922 TI - Immunoglobulin-bearing lymphocytes in monoclonal gammapathies. PMID- 4142923 TI - [Synchronization of estrus in heifers with BOVISYNCHRON]. AB - Heifers were each given 2ml of 1% solution of chlormadinone (CAP, Bovisynchron) for 15 days. Those in group I received one daily dose, while group II received half the dose twice a day. Oestrus was synchronized in all but two heifers. In group II there was a concentrated occurrence of oestrus, so that all heifers could be inseminated on the 5th and 6th days, and earlier inseminations were not needed. This decreased the time required and the number of semen pellets. Results of insemination in two of the three subgroups of group II were 51% in one and 61% in the other, compared with between 32 and 39% in the other subgroup and in group I. Ways of improving the results are discussed. PMID- 4142924 TI - [Pour-on method of administering chlormadinone acetate for estrus synchronization in heifers]. AB - Experiments with chlormadinone (Bovisynchron) on 380 heifers and 60 cows showed that the drug was absorbed following pour-on application. A volume of 2 ml was rubbed into the skin of the back anterior to the sacrum, once daily for 15 days. Residual amounts were removed 24 hours after the final application by washing the hair coat with dimethyl sulphoxide solution. Insemination was performed at the same time as after oral administration. The pour-on method was particularly suitable for heifers and cows out at pasture. PMID- 4142925 TI - [Functional cytology of bovine adenohypophysis and the effects of mestranol and chlormadinone acetate]. AB - The synthetic oestrogen mestranol, given by mouth to young bulls, appeared to stimulate chromophobe cells of the anterior lobe of the pituitary, indicating stimulation of ACTH secretion. The mass of the pituitary was also increased by administration of 5 mg mestranol daily for 130 days. This hypertrophy was prevented by a single intramuscular injection of chlormadinone acetate. The anterior epithelium of the hypophyseal cavity reacted tooestrogen administration by increased secretory activity. PMID- 4142926 TI - Granular abate for control of mosquitoes larvae. PMID- 4142927 TI - Turnover of myelin and other structural proteins in the developing rat brain. AB - 1. Protein metabolism of myelin and other subcellular components from developing rat brain was studied for periods from 5h to 210 days after intraperitoneal injection of [(3)H]lysine and [(14)C]glucose. 2. Half-lives for total brain proteins (t(0.5)) were 27 days after [(3)H]lysine and 4 days after [(14)C]glucose injection. 3. Factors accounting for the difference in the turnover rates obtained with different precursors, and the problem of reutilization of the label were investigated. 4. The catabolism of purified myelin proteins was studied and the half-lives of individual myelin proteins were calculated. 5. Myelin basic proteins turned over at two different rates. Half-life of the fast component of myelin basic proteins was 19-22 days and the slow component exhibited a high degree of metabolic stability. 6. Proteolipid protein underwent slow turnover. High-molecular-weight Wolfgram (1966) proteins underwent (relatively) fast metabolism (t(0.5) of 17-22 days). PMID- 4142928 TI - The isolation and identification of the P-component of normal human plasma proteins. AB - A normal human plasma protein called the P-component, which has a reaction of identity with the pentagonal structure found in amyloid-laden organs, has been isolated and identified with a recently characterized protein, the 9.5S alpha(1) glycoprotein. PMID- 4142929 TI - Intervention programmes for preschool children with delayed language development: a preliminary report. PMID- 4142930 TI - G-banding of 3 multiple myeloma marker chromosomes. PMID- 4142932 TI - [The diagnostic value of hyper-alpha-2 globulinemia in neoplasms of the male urinary and genital systems]. PMID- 4142931 TI - [Collection of information during medical therapeutic trials in oncology. Proposition of a standard record form]. PMID- 4142933 TI - [Serodiagnosis of amoebiasis through a rapid agglutination test of sensitized late particles. Results of 462 examinations and comparison with indirect immunofluorescence reaction]. PMID- 4142934 TI - [Haptoglobin level, malaria and anemia in the African adult. Complementary findings, prospects and methodologic problems]. PMID- 4142935 TI - [Serodiagnosis of bilharziasis by immunofluorescence of furcocercaria fixed on slides. Comparison with frozen sections of adult worms]. PMID- 4142936 TI - Factors affecting the efficacy of live poliovirus vaccine in warm climates. Efficacy of type 1 Sabin vaccine administered together with antihuman gamma globulin horse serum to breast-fed and artificially fed infants in Uganda. AB - A virologically controlled field trial was conducted with live monovalent type 1 poliovirus vaccine in children aged 3-30 months living in a rural area of Uganda, in an attempt to find out the reason for the poor efficacy of such vaccine often observed in countries with a warm climate. Groups of breast-fed and of artificially fed infants received the vaccine orally, either alone or mixed with horse serum prepared against partly purified human gamma-globulin. Irrespective of the diet, the "take rate"-measured by the rates of vaccine virus excretion and of antibody conversion-was found to be poor when the vaccine was given alone but satisfactory when it was given together with the horse antiserum. However, the extent and duration of vaccine virus multiplication in the intestinal tract proved to be limited and the mean antibody level elicited by the vaccination, irrespective of the schedule of vaccine administration, was low. These results, besides indicating that breast-feeding does not influence the efficacy of vaccination in the age groups studied, revealed the presence of an inhibitor in the alimentary tract. This inhibitor acts against the multiplication of vaccine virus, which may be blocked by antibodies in the horse antiserum for a limited period at the time of vaccination. Interference between the enteroviruses and the vaccine strain was also found to be responsible for decreasing the efficacy of vaccination, though its role was secondary to that of the inhibitor. Revaccination experiments showed that the effects of both inhibitor and interference may be overcome by repeated administration of the vaccine. PMID- 4142938 TI - [Evolution of antigenic determinants of various strains of Saccharomyces cerevisiae Hansen during growth]. PMID- 4142937 TI - [Ethidium bromhydrate effect on L 1210 mouse leukemia]. PMID- 4142939 TI - [Participation of carbohydrate structures in the allotypic specificity of rabbit IgG]. PMID- 4142940 TI - [Immunofluorescent study of morphologic mutants of Saccharomyces cerevisiae Hansen]. PMID- 4142941 TI - [Reentry phenomenon in cardiac rhythm disorders]. PMID- 4142942 TI - [Heinrich Zangger]. PMID- 4142943 TI - [Functional state of the liver in workers having occupational contact with aminazine and certain other compounds]. PMID- 4142944 TI - [Dynamic study on the indices of vascular fragility]. PMID- 4142945 TI - [Blood volume replacement using hydroxyethyl starch or Dextran 60]. PMID- 4142946 TI - [Clinical plasma substitution with gelatin: A 12-year experience with 39,320 units of Physiogel]. PMID- 4142947 TI - [Serologic examinations of blood donors. III. Detection of liver damage in the blood of blood donors]. PMID- 4142948 TI - Association of serum and red cell phenotypes and Australian antigen in Down's syndrome. PMID- 4142949 TI - A possible case of partial trisomy for chromosome 22: further evidence from Giemsa banding studies. PMID- 4142950 TI - Recording pulsations in echo-encephalography. PMID- 4142951 TI - Computer-terminal operating and communication aid for the severely handicapped. PMID- 4142952 TI - Television in the Faculty of Medicine at Glasgow University. A two-year report. PMID- 4142953 TI - A new approach to teaching histology at the University of Louvain. PMID- 4142954 TI - A positive method of focusing x-ray lantern slides. PMID- 4142955 TI - Reserpine and breast cancer. PMID- 4142956 TI - Retrospective study of the association between use of rauwolfia derivatives and breast cancer in English women. PMID- 4142957 TI - Reserpine use in relation to breast cancer. PMID- 4142958 TI - Angina pectoris with normal coronary arteries. Transvenous myocardial biopsy in diagnosis. PMID- 4142959 TI - A new approach to viral chemotherapy. Inhibitors of glycoprotein synthesis. PMID- 4142960 TI - Significance of complement-positive Coombs test in patients with glomerular disease. PMID- 4142961 TI - T or B cell origin of some non-Hodgkin's lymphomas. PMID- 4142962 TI - Cell-mediated immunity and phagocytosis and killing function in children with severe iron-deficiency anaemia. PMID- 4142963 TI - Changing patterns in epidemiology of Crohn's disease. PMID- 4142964 TI - Ascorbic-acid saturation and ethanol metabolism. PMID- 4142965 TI - Localisation of deep-venous thrombosis using technetium-99m-labelled urokinase. PMID- 4142966 TI - Poor kidney-transplant survival in recipients with frozen-blood transfusions or no transfusions. PMID- 4142967 TI - Automatic measurement of chest drainage by an ultrasonic system. PMID- 4142968 TI - Editorial: Rauwolfia derivatives and cancer. PMID- 4142969 TI - Editorial: Myocardial ischaemia without coronary arterial disease. PMID- 4142970 TI - Editorial: Monoamine oxidase and migraine-a causal link? PMID- 4142971 TI - Editorial: Jack becomes master? PMID- 4142972 TI - Editorial: Injury before birth. PMID- 4142973 TI - Editorial: Prescribers' choice. PMID- 4142974 TI - Editorial: Biological effects of asbestos. PMID- 4142975 TI - Editorial: Facts and myths about sickness absence. PMID- 4142977 TI - The benzodiazepine bonanza. PMID- 4142976 TI - Progeny of childhood-cancer survivors. PMID- 4142978 TI - Letter: Evolution of kwashiorkor and marasmus. PMID- 4142979 TI - Editorial: Protein requirement. PMID- 4142980 TI - Letter: Follow-up of patient with portacaval shunt for the treatment of hyperlipidaemia. PMID- 4142981 TI - Letter: Legal status of the unborn. PMID- 4142982 TI - Letter: Rapid chromosome diagnosis. PMID- 4142983 TI - Letter: Reye's syndrome. PMID- 4142984 TI - Letter: Unsaturated fatty acids and renal transplantation. PMID- 4142985 TI - Letter: Prolactin and migraine. PMID- 4142986 TI - Letter: IgE-containing plasma cells in acute tubulo-interstitial nephropathy. PMID- 4142987 TI - Letter: Microbial-antigen detection. PMID- 4142988 TI - Letter: Microbial-antigen detection and complex antisera. PMID- 4142989 TI - Letter: Classification and nomenclature of malformations. PMID- 4142990 TI - Low mitotic activity of granulopoietic precursor cells in Ph1-chromosome-negative chronic myeloid leukaemia. PMID- 4142991 TI - Letter: Secular trends in leukaemia mortality. PMID- 4142992 TI - Letter: Tinidazole in treatment of giardiasis. PMID- 4142993 TI - Letter: Oxolinic acid in urinary infections. PMID- 4142994 TI - Letter: Thyrotropin-releasing hormone and depression. PMID- 4142995 TI - Letter: Propranolol and pregnancy. PMID- 4142996 TI - Letter: Thrombocytopenia during treatment with ampicillin. PMID- 4142997 TI - Letter: Acute non-allergic reaction to aqueous procaine penicillin. PMID- 4142998 TI - Letter: Are Pompidou's refringent lymphocytes thymus-dependent? PMID- 4142999 TI - Letter: Inhibition of lymphocyte response to stimulants by unsaturated fatty acids and prostaglandins. PMID- 4143000 TI - Letter: Scientific medicine. PMID- 4143001 TI - Letter: "Rotavirus" in gastroenteritis. PMID- 4143002 TI - Letter: HL-A antigens and M.I.C. responsiveness in systemic lupus erythematosus. PMID- 4143003 TI - Letter: HL-A antigens and coeliac disease. PMID- 4143004 TI - Letter: Non-specific enhancement of glomerular filtration by corticosteroids. PMID- 4143005 TI - Letter: Neostigmine after bowel surgery. PMID- 4143006 TI - Letter: Tumour-cell mucous protein and C.E.A. PMID- 4143007 TI - Comparative trial of L-tryptophan and E.C.T. in severe depressive illness. PMID- 4143008 TI - Acquired valvular heart-disease in patients who keep pet birds. PMID- 4143009 TI - Some effects of changing to low-tar and low-nicotine cigarettes. PMID- 4143010 TI - Effect of renal transplantation of uraemic neuropathy. PMID- 4143011 TI - Single-dose doxycycline treatment of louse-borne relapsing fever and epidemic typhus. PMID- 4143012 TI - Minocycline: Possible vestibular side-effects. PMID- 4143013 TI - Transplacental transmission of hepatitis-B virus by symptom-free chronic carrier mothers. PMID- 4143014 TI - Pitfalls in the study of hepatitis A. PMID- 4143015 TI - Clinical significance of T-cells in chronic lymphocytic leukaemia. PMID- 4143016 TI - Expression of human T and B lymphocyte cell-surface markers on leukaemic cells. PMID- 4143017 TI - Spinal-fluid lysozyme in the diagnosis of central-nervous-system tumours. PMID- 4143018 TI - Hand-held dynamometer for evaluating voluntary-muscle function. PMID- 4143019 TI - A spring-heeled rocker-soled plaster boot. PMID- 4143020 TI - Editorial: Exploiting interferons. PMID- 4143021 TI - Editorial: Treatment of sickle-cell crises. PMID- 4143022 TI - Editorial: Floral strategy. PMID- 4143023 TI - Editorial: Sandbags from Mrs Castle. PMID- 4143024 TI - Editorial: The menace of cholera. PMID- 4143025 TI - Editorial: Research at large. PMID- 4143026 TI - Mesial temporal (Ammon's horn) sclerosis as a common cause of epilepsy. Aetiology, treatment, and prevention. PMID- 4143027 TI - What dose the general practitioner want to know about the cancer patient? PMID- 4143028 TI - Letter: Whooping-cough vaccination. PMID- 4143029 TI - Letter: Rauwolfia derivatives and cancer. PMID- 4143030 TI - Human placental lactogen and fetal abnormality. PMID- 4143031 TI - Letter: Clinical trials with vitamin C. PMID- 4143032 TI - Letter: Ascorbic acid and long-term steroids. PMID- 4143033 TI - Letter: Omental transposition for drainage of cerebrospinal fluid. PMID- 4143034 TI - Letter: Atrophic gastritis and dermatitis herpetiformis. PMID- 4143036 TI - Letter: Home treatment for patients with haemophilia. PMID- 4143035 TI - Letter: Natural history of atrophic gastritis. PMID- 4143037 TI - Letter: Judging clinical competence and videotape techniques. PMID- 4143038 TI - Letter: Lymphocyte hazards to the fetus. PMID- 4143040 TI - Letter: Treatment of congenital dislocation of the hip. PMID- 4143039 TI - Letter: Circadian rhythm in murine tolerance of daunorubicin. PMID- 4143041 TI - Letter: Mobile coronary care. PMID- 4143042 TI - Letter: Behavior of tumours in conditions of experimental magnesium deficiency. PMID- 4143043 TI - Letter: Allergy, tolerance, and immunoglobulin A. PMID- 4143044 TI - Letter: Dangers of corticotrophin in phaeochromocytoma. PMID- 4143045 TI - Letter: Infection in the sink. PMID- 4143046 TI - Letter: Papovavirions in urothelium of treated lymphoma patient. PMID- 4143047 TI - Letter: Mortality among vinyl-chloride workers. PMID- 4143048 TI - Letter: Subcutaneous heparin. PMID- 4143049 TI - Letter: Angiokeratoma corporis diffusum and lysosomal enzyme deficiency. PMID- 4143050 TI - Letter: Ultrasonic cephalometry. PMID- 4143051 TI - Letter: B.C.G. in rheumatoid arthritis. PMID- 4143052 TI - Letter: Carbon monoxide, smoking, and constitution. PMID- 4143053 TI - Letter: Does hiatus hernia affect competence of the gastrooesophageal sphincter? PMID- 4143054 TI - Letter: Intestinal potential difference during glucose absorption. PMID- 4143055 TI - Letter: Speaking aid. PMID- 4143056 TI - Letter: Haemolytic-uraemic syndrome: evidence for intravascular C3 activation. PMID- 4143057 TI - Letter: Ageing, immune response, and mortality. PMID- 4143059 TI - Fergus Robert Ferguson. PMID- 4143058 TI - Letter: Termination by prostaglandin pellets in very early pregnancy. PMID- 4143060 TI - [Refractoriness of hens towards Trypanosoma (Schizotrypanum) cruzi. III. Dissociation of phenomena of the refractory state and lysis of the epimastigotes by fowl serum]. PMID- 4143061 TI - [Study of the antigenic affinity of Pseudomonas vignae and Pseudomonas phaseolicola phages]. PMID- 4143062 TI - Relative effectiveness of various solvents for oil red O. PMID- 4143063 TI - Histochemical identification of primordial germ cells in human embryos by PAS reaction. PMID- 4143064 TI - [Therapy of malignant bone tumors]. PMID- 4143065 TI - [Dentine structures]. PMID- 4143066 TI - [The value of long-term injectable corticoid therapy in cancer of the mouth]. PMID- 4143067 TI - [Anatomo-clinical study of a case of myasthenic syndrome with hyperthyroidism]. PMID- 4143068 TI - Reaction spectrum of human HBs antibodies. PMID- 4143069 TI - [Lead contamination of feed and its effect on the animal body]. PMID- 4143070 TI - Sinusitis -- 1974. PMID- 4143071 TI - Photocoagulation of exudative senile maculopathy. A followup report. PMID- 4143072 TI - [Alpha-fetoprotein in clinical pathology]. PMID- 4143073 TI - [Differences in the antigenic structure of strains of the foot-and-mouth disease virus]. PMID- 4143074 TI - [Effect of stimulating doses of antitesticular cytotoxic serum on the excretion of sex hormones in impotence]. PMID- 4143075 TI - Laboratory techniques in rabies: histopathological diagnosis. PMID- 4143076 TI - Activation of peripheral lymphocytes in the course of experimental allergic encephalomyelitis in the guinea-pig. PMID- 4143077 TI - [On the anamnestic reaction by non-specific stimulation (author's transl)]. PMID- 4143078 TI - [On the specificity of the intracutaneous test with vaccinia antigen (author's transl)]. PMID- 4143079 TI - [Further studies of the nude (spine-free) initial zone of the apical dendrite of cortical pyramidal cells in the albino rat]. PMID- 4143080 TI - [Search for a differentiated pathogenetic therapy and the prevention of disseminated sclerosis]. PMID- 4143081 TI - Identification of climbing fibres in the cerebellar cortex of the rat by means of 3H-leucine EM-autoradiography. PMID- 4143082 TI - Retrograde intracellular staining and identification gastropoda neurones with CoCl2. PMID- 4143083 TI - [Morphological and physiological effect of 5-azacytidine on nucleoli]. PMID- 4143084 TI - [Dyes and dye problems of histologists and histochemists]. PMID- 4143085 TI - [Dye configuration and its influence on staining]. PMID- 4143086 TI - Effects on staining of the presence of various kinds of dye impurities. PMID- 4143087 TI - [Purification of a dye, demonstrated with acridine orange as an example]. PMID- 4143088 TI - [Determination of staining quality of industrial dyes. studies with neutral red as example]. PMID- 4143089 TI - [Metachromatic reactions in vitro; influence of inorganic and organic acids]. PMID- 4143090 TI - [Influence of inorganic and organic salts on binding of polysaccharides with thiazine dyes]. PMID- 4143091 TI - [Effect of nucleic acids on the metachromatic reaction]. PMID- 4143092 TI - Etomidate, a new intravenous hypnotic. PMID- 4143093 TI - [Histologic study of hereditary dentinogenesis imperfecta]. PMID- 4143094 TI - [Possibilities of errors in the determination and evaluation of rheumatoid factor reactions]. PMID- 4143095 TI - [Special microscopic technic for the characterization of aerosols]. PMID- 4143096 TI - [2-year computerized statistical study of the efficacy of supplementary antimitotic treatment of cancers of the larynx and pharynx]. PMID- 4143097 TI - [Histoenzymologic and ultrastructural study of the action of bleomycin on the normal hepatocyte]. PMID- 4143098 TI - [Prozone phenomenon in immunofluorescence and immunoperoxidase: a possible mechanism (author's transl)]. PMID- 4143099 TI - [Use of water-soluble adjuvant fraction from "Mycobacterium smegmatis" with encephalitogenic basic protein to induce autoimmune experimental allergic encephalomyelitis in guinea pigs (author's transl)]. PMID- 4143100 TI - Laboratory investigations on neuroparalytic accidents associated to suckling mouse brain rabies vaccine. II.--Encephalitogenicity of murine brain myelin preparations. PMID- 4143101 TI - [Ventricular tachycardias through re-entry. Late complication of myocardial infarction]. PMID- 4143102 TI - [Usefullness of continuous electrocardiographic recording in the ambulatory patient]. PMID- 4143103 TI - A study of the distribution of the major subtypes of hepatitis B antigen in Melbourne. PMID- 4143105 TI - [Axonal transport of labeled proteins in crayfish giant motor neuron]. PMID- 4143104 TI - Combined chemotherapy, radiotherapy, and surgery in the treatment of advanced but localized solid malignant tumours. PMID- 4143106 TI - Studies on antigenic competition. V. Evidence for the involvement of a thymic derived cortisone-sensitive cell in the mediation of antigenic competition. PMID- 4143107 TI - Thymus cell traffic induced by antigen stimulation. PMID- 4143108 TI - Induction of anti-hapten antibody response by hapten-isologous carrier conjugate. I. Development of hapten-reactive helper cells by hapten-isologous carrier. PMID- 4143109 TI - The influence of epitope density on the immunological properties of hapten protein conjugates. I. Characteristics of the immune response to hapten-coupled albumen with varying epitope density. PMID- 4143110 TI - Immune responses to myelin basic protein in mycobacterial-induced suppression of experimental allergic encephalomyelitis. PMID- 4143111 TI - Antigen cross-reactivity in the macrophage electrophoretic mobility test. A study using cellular affinity chromatography. PMID- 4143112 TI - Phagocyte function in protein-calorie malnutrition. PMID- 4143113 TI - Chronic infections in a family with hereditary deficiency of IgG2 and IgG4. PMID- 4143114 TI - Studies into the occurrence of soluble antigen-antibody complexes in disease. VI. Further characterization of the biological and physical properties of the rheumatoid biologically active factor (RBAF). PMID- 4143116 TI - Splitting of human thyroglobulin. III. Comparison of fragments obtained during enzymatic digestion and by reduction and alkylation. PMID- 4143118 TI - Immunoelectrophoretic analysis and radial immunodiffusion assay using plasminogen purified from fresh human plasma. PMID- 4143117 TI - Cells binding the antigen keyhole limpet haemocyanin in the peripheral blood and in the lymphocyte cultures of non-immune and immunized human subjects. PMID- 4143120 TI - Hageman factor-independent fibrinolytic pathway. PMID- 4143122 TI - Cilia membrane abnormalities induced by streptomycin and other aminoglycoside antibiotics in Stentor coeruleus. PMID- 4143123 TI - [The antithyrotropic effect of magnesium ions]. PMID- 4143124 TI - [Changes in serum proteins in thymectomized rats with experimental myocarditis and arthritis]. PMID- 4143125 TI - [Immune changes in adult guinea pigs at different periods following thymectomy]. PMID- 4143126 TI - [The functional state of the thyroid gland in rats with uranium poisoning]. PMID- 4143127 TI - [Quantitative-morphological studies on the effect of gestagens on the hypothalamic-adenohypophyseal system in cattle]. PMID- 4143128 TI - [Steroid metabolism in primates. XV. Excretion of C19 and C21 steroids in the urine of baboons (Papio hamadryas) after long-term treatment with a combination of mestranol-chlormadinone acetate]. PMID- 4143129 TI - [Morphology of the rat placenta in experimental, hormonally-induced, prolonged pregnancy. I. Placenta of live and freshly-killed rat fetuses]. PMID- 4143130 TI - Perceptual-motor programs. PMID- 4143131 TI - The pituitary gland of a teleost, Nandus nandus (Ham.). PMID- 4143132 TI - Studies on the renal organ of the percoid teleost fish, Nandus. I. Morphohistological and histochemical considerations. PMID- 4143133 TI - [Certain results of operative treatment of esophageal cancer]. PMID- 4143135 TI - Attitudes on population. PMID- 4143134 TI - Some central nervous system actions of 5-(3 dimethylamino-2-methyl-propyl) dibenzo [a, d] [1,4] cyclooctadiene hydrochloride. PMID- 4143136 TI - [Hemotherapy "made to measure", or, selective use of blood and blood components]. PMID- 4143137 TI - [Histochemical study of the organic structure of Retzius' striae]. PMID- 4143138 TI - [Effects of experimental occlusal overload on the rat periodontium]. PMID- 4143139 TI - Intracisternal inclusion bodies induced in animals: their transformation and significance. PMID- 4143140 TI - [Conservative treatment of prostatic adenoma]. PMID- 4143141 TI - A teaching-aid programmer. PMID- 4143142 TI - Sectioning and staining of leucocyte migration cultures for light microscopy. PMID- 4143143 TI - [The human chromosomes. The history of their investigation]. PMID- 4143144 TI - [Problems of etiotropic therapy of influenza and other respiratory viral infections]. PMID- 4143145 TI - [Taste and smell. A surprising exploration]. PMID- 4143146 TI - [Method of staining of cyanoacrylic tissue adhesives using oil red O]. PMID- 4143147 TI - [Behavior of some serum proteins in chronic liver disease, anascitic and ascitic liver cirrhosis]. PMID- 4143148 TI - [Supravital staining of the peripheral blood and cultivated lymphocytes with toluidine blue]. PMID- 4143150 TI - [Differential staining of Allium cera L. chromosomes]. PMID- 4143149 TI - [The function of liver mitochondria after steroid administration]. PMID- 4143151 TI - [Rhythm disorders in patients in the acute stages of myocardial infarction]. PMID- 4143152 TI - [Establishing hygienic margins for water pollutants, illustrated on the example of DDT and Lindane]. PMID- 4143153 TI - [Gamma globulin antibody formation following anti-D IgG prophylaxis (author's transl)]. PMID- 4143154 TI - The influence of antigen-antibody-complexes on the cellular antibody-formation. PMID- 4143155 TI - [Attempt at classifying specific thrombocyte antigens 10th communication: evidence of specific platelet antigens in human organs (author's transl)]. PMID- 4143156 TI - [Determination of penicillin and penicillinantibodies by immune hemolysis. II. Quantitation of sodium penicillin G by means of passive immune hemolysis (author's transl)]. PMID- 4143157 TI - Appearance of the encephalitogenic activity in the non-encephalitogenic fraction from human brain during a prolonged storage. PMID- 4143158 TI - Antigens in the spleen: localization of labelled antigen in the spleen of normal rabbits and rabbits preimmunized with a non related antigen. PMID- 4143159 TI - [A specific striated muscle antigen of Papio papio monkey (author's transl)]. PMID- 4143160 TI - Antigenic heterogeneity of J chain from human IgM. PMID- 4143161 TI - Immunoglobulin classes of human antitoxin after tetanus vaccination studied by immunofluorescence with agarose bound tetanus toxoid. PMID- 4143162 TI - More sensitive quantitation of low level serum IgE and alpha1-fetoprotein by single radial immunodiffusion using radioiodine labeled IgE or alpha1-fetoprotein as marker. PMID- 4143163 TI - Antiepithelial antibodies in the serum of patients with benign and malignant diseases of the prostate. PMID- 4143164 TI - Histocompatibility antigens of patients with rheumatoid arthritis. PMID- 4143165 TI - [Quantitative immunoelectrophoresis as a method for determination of hepatitis B antigen. Standardization and comparison with other methods (author's transl)]. PMID- 4143166 TI - [On pseudomonovalent penicilloyl carbohydrates (author's transl)]. PMID- 4143167 TI - Immunoglobulin receptors on "T" lymphocyte surface. PMID- 4143168 TI - Antigenic correlations between brain and thymus. III. Reciprocal blocking of antigenic determinants on mouse brain and thymocytes by anti-mouse-brain- and anti-thy-1.2 sera. PMID- 4143169 TI - [The production of blood typing sera from raw material of animal origin (author's transl)]. PMID- 4143170 TI - The unresponsiveness of wistar rats to bovine gamma globulins. PMID- 4143171 TI - [The effect of polyethylene glycol and dextran on the immunoelectrophoresis (author's transl)]. PMID- 4143172 TI - [Active enhancement of canine liver allografts - simultaneous pretreatment with donor specific semisoluble antigen and prednisolon (author's transl)]. PMID- 4143174 TI - [Masked metachromasia of C-cells in the thyroid gland of the rat]. PMID- 4143173 TI - [Molecular association of beta2-microglobulin with serological defined antigens of the lymphocyte surface (author's transl)]. PMID- 4143175 TI - [Simultaneous transfer to "Escherichia coli" K12 of "Shigella flexneri" F6S Hfr antigenic determinants and resistance to T phages (author's transl)]. PMID- 4143176 TI - [The staining of histological preparations with the use of rywanol (2,5 diamino-7 etoxacridine) in fluorescence microscopy (author's transl)]. PMID- 4143177 TI - Effect of serum alpha2-macroglobulin on the trypsin-soybean trypsin inhibitor complex. PMID- 4143178 TI - [Short-term treatment of pulmonary tuberculosis]. PMID- 4143179 TI - [Controlled therapeutic study of 5 intermittent chemotherapy regimens for pulmonary tuberculosis. 4th international study of the UICT]. PMID- 4143180 TI - Concurrent comparison of an unsupervised daily oral regimen of thiacetazone plus isoniazid and a fully supervised twice-weekly regimen of streptomycin plus isoniazid in the domiciliary treatment of pulmonary tuberculosis--a co-operative investigation. PMID- 4143181 TI - Radioimmunoassay and saturation analysis. Tumor-associated antigens. PMID- 4143182 TI - [Isolation of some rat serum proteins during inflammatory reaction]. PMID- 4143183 TI - Urinary and biliary metabolites of 17alpha-acetoxy-6-chloro-4,6-pregnadiene-3,20 dione in the rabbit. PMID- 4143184 TI - Antibody reactions to virus-specific early antigens (EA) in patients with cytomegalovirus (CMV) infection. PMID- 4143185 TI - A serum inhibitor of the heterophile antibody in infectious mononucleosis. PMID- 4143186 TI - Liver-specific antigens of different species. II. Localization of a membrane antigen at cell surface of isolated hepatocytes. PMID- 4143187 TI - Lymphocytes in rheumatoid arthritis. II. Quantitative binding of phytomitogens. PMID- 4143188 TI - Rabbit b4 light chain fragments bearing isotypic and allotypic specificities. PMID- 4143189 TI - Spontaneously arising cytotoxicity to the P-815-Y mastocytoma in NZB mice. PMID- 4143196 TI - An antibody to isogeneic fibroblasts in the serum of diseased NZB mice. PMID- 4143194 TI - Heterologous specific antiserum for identification of human T lymphocytes. PMID- 4143195 TI - Cryoglobulins in acute and chronic liver diseases. PMID- 4143197 TI - Cross-reactivity of T-cell 'helper' function. PMID- 4143199 TI - The macrophage electrophoretic mobility (MEM) test for malignant disease. Further clinical investigations and studies on macrophage slowing factors. PMID- 4143200 TI - Interaction of poly i:c with the cell membrane in trichomonas vaginalis. PMID- 4143201 TI - Aspects of tolerance to RNA in different strains of mice. PMID- 4143202 TI - Amniotic fluid concentrations of alpha-fetoprotein (AFP) in early normal pregnancy, and pregnancy complicated by neural tube defects. A review of 18 months experience. PMID- 4143203 TI - The presence of alpha-amino-beta, gamma-dihydroxybutyric acid in hydrolysates of actinomycin Z1. PMID- 4143204 TI - Induction of colicin E1 synthesis by neocarzinostatin and bleomycin. PMID- 4143205 TI - Total synthesis of streptomycin. PMID- 4143206 TI - Alpha fetoprotein: Physiology and pathology during pregnancy and application to antenatal diagnosis. PMID- 4143207 TI - Practical clinical aspects of RH-prophylaxis. PMID- 4143208 TI - Medical illustration in the new Health Services. 2. White papers, green papers, and grey books. PMID- 4143209 TI - A role for medical illustration in developing countries. PMID- 4143211 TI - Phantom sync-pulsing of audio tapes. PMID- 4143210 TI - The Self-Instructional Materials Project, National Health Sciences Consortium. PMID- 4143212 TI - Teaching basic pharmacology to medical students. An experimental self instructional approach. PMID- 4143213 TI - Teacher participation in media centre development. PMID- 4143214 TI - An inexpensive "splitter box" for facilitating multiple simultaneous slide projections. PMID- 4143215 TI - Muscle relaxants -- their road towards perfection. PMID- 4143216 TI - Cerebral microcirculation: studies by fluorescein angiography and local cerebral blood flow measurements by radioisotopes. PMID- 4143217 TI - Fundoscopy of the retinal nerve fiber layer in neurosurgical practice. PMID- 4143218 TI - Stereotactic thalamotomy and L-dopa induced involuntary movement in Parkinsonism. PMID- 4143219 TI - The role of cyclic 3', 5'-AMP on trauma-induced alteration of energy metabolism in cerebral cortex in vivo. PMID- 4143220 TI - Fine structure of human epileptogenic foci--preliminary report. PMID- 4143221 TI - [Extracellular occurrence of reverse transcriptases in human malignant diseases (author's transl)]. PMID- 4143222 TI - Prisons, shelters, and homeless men. PMID- 4143223 TI - [Current treatment of severe tetanus]. PMID- 4143224 TI - Liver studies in the thorotrast patients - laboratory and clinical findings (study of 175 cases). PMID- 4143225 TI - Recent observations regarding retinoblastoma. II. An enxyme study of retinoblastoma. PMID- 4143226 TI - [Use of gamma globulin from placental blood]. PMID- 4143227 TI - State of the nervous system in workers with a long-term occupational contact with hexachlorocyclohexane and initial products of its synthesis. PMID- 4143228 TI - [Diagnosis and complex treatment of staphylococcal infections]. PMID- 4143229 TI - [Certain indicators of liver function and histamine metabolism in patients with coronary atherosclerosis]. PMID- 4143230 TI - [Determination of the degree of allergic alteration of leukocytes by use of staining for peroxidase]. PMID- 4143231 TI - [Current laboratory methods of diagnosis of the functional state of the thyroid gland]. PMID- 4143232 TI - [Studies on the non-specificity of rheumatoid factor determination (author's transl)]. PMID- 4143233 TI - In vivo bound immunoglobulins in the human prostate--their identification and possible significance. PMID- 4143234 TI - Gene amplification in cell-free systems. PMID- 4143235 TI - [The metabolism of 28 serum proteins in a human liver transplantation (author's transl)]. PMID- 4143236 TI - [Detection of antibody-forming cells by means of local hemolysis in gel (LHG) in mice and pigs after immunization with infectious or inactivated foot-and-mouth disease virus (author's transl)]. PMID- 4143237 TI - In vitro demonstration of cell-mediated immunity against human renal carcinoma assessed by the leukocyte migration assay. PMID- 4143238 TI - Aedes aegypti surveillance and control in the South Pacific. PMID- 4143239 TI - Polarization-optical study of the ultrastructure of the ciliata Kahlia acrobates (Horvath). PMID- 4143240 TI - The mesangial cell in glomerulonephritis. PMID- 4143241 TI - The pathogenetic role of the coagulation process in glomerular diseases of immunologic origin. AB - The experimental and clinical observations analyzed in this review suggest that the deposition of fibrin within glomeruli is an important pathogenic mechanism in the series of events leading to progressive destruction of glomerular capillaries. Neither the causal factors nor the consequences of this type of reaction are peculiar to the glomerulus. Fibrin deposits can occur in any injured blood vessel and, if not rapidly dealt with by fibrinolysis, will lead to endothelial changes and the development of organizing thrombi. It seems that glomerular capillaries are especially vulnerable; there are several reasons for this. First, some immunologic reactions are triggered within the glomeruli and thus produce a local inflammatory response, leading to fibrin deposition. Secondly, the glomerular filtration function allows a progressive local accumulation of potentially damaging particles, such as circulating fibrinogen derivatives (formed during generalized intravascular clotting), or phlogistic immune complexes (as a result of systemic antigen-antibody interaction); these too cause local injury and fibrin deposition. Finally, the glomerular obliteration resulting from the organization of such fibrin deposits leads to irreversible damage and so has more serious implications for the patient than if the lesions occurred elsewhere, where the formation of functionally useful new capillaries is often possible. It seems reasonable to propose, therefore, that the use of anticoagulant may be natural therapy in cases with the risk of rapid, massive, and continuous fibrin accumulation in glomeruli, where glomerular sclerosis and irreversible renal failure are likely. PMID- 4143242 TI - [Elimination of lipoproteins, alpha 1 antitrypsin and complement activity of human serum after agitation with iso-amyl alcohol. A study with special reference to bidimensional immunoelectrophoresis]. PMID- 4143243 TI - [Swine vesicular disease: properties of the virus strain France 1/73 (author's transl)]. PMID- 4143244 TI - [Replication of adenovirus type 5 in culture of cord blood lymphocytes (author's transl)]. PMID- 4143248 TI - Serum IgE in immune deficiency disorders. PMID- 4143250 TI - Immunochemical studies of infectious mononucleosis. III. Isolation and characterization of heterophile antibodies. PMID- 4143251 TI - Effect of disodium cromoglycate on antigen-evoked histamine release from human skin. PMID- 4143252 TI - Preliminary studies on the synthesis of alpha2-macroglobulin by human lymphocytes in vitro. PMID- 4143253 TI - Effect of continuous low dosage (0.5 mg.) chlormadinone acetate on the genital tract of women. PMID- 4143254 TI - [Evaluation of Eliasson's method as a live-dead differential staining of boar spermatozoa (author's transl)]. PMID- 4143255 TI - [Autoradiography on the embryonic disc of rabbit blastocysts (author's transl)]. PMID- 4143256 TI - [The behavior of the gonadotropins FSH and LH during and after treatment with estrogenic and progestational drugs]. PMID- 4143257 TI - Studies with LH-RF (Gn-RF) in cattle. PMID- 4143259 TI - A primer to histotechnology. PMID- 4143258 TI - The treatment of noncycling mares by oral application of chlormadinone acetate (CAP). PMID- 4143260 TI - [Special education programs]. PMID- 4143261 TI - Histamine and serotonin release from isolated rat peritoneal mast cells by arginine rich nuclear proteins. PMID- 4143262 TI - Some effects of dibutyryl cyclic adenosine monophosphate (DBcAMP) on rabbit bone marrow cells in culture: cell clumping and cholinesterase production. PMID- 4143263 TI - Innovate teaching techniques. PMID- 4143265 TI - [Histological study of the guinea pig ovary before and after the intake of clomifene citrate (author's transl)]. PMID- 4143264 TI - Effects of steroids upon the liver ultrastructure. PMID- 4143266 TI - The contribution of some histochemical methods to the diagnosis of breast cancer. PMID- 4143267 TI - Systemic effects of eye drops. PMID- 4143269 TI - The value of intensive care. PMID- 4143268 TI - Lipotriad. A double-blind clinical trial. PMID- 4143270 TI - Agar gel electrophoresis of unconcentrated cerebrospinal fluid: the degenerative type. AB - Five to 10 mul of 196 cerebrospinal fluid samples were subjected to agar gel electrophoresis without previous concentration. No "degenerative" pattern was found to be correlated with any clinical diagnosis or group of diagnoses, Repeated freezing and thawing appears to have different effects on the different fractions. The oligoclonica gamma patterns in shown to be demonstrable by this method. PMID- 4143271 TI - Preparation of aminoazo dye induced rat hepatoma membrane fractions retaining tumour specific antigen. AB - Membrane fractions were isolated from homogenates of an aminoazo dye induced rat hepatoma (hepatoma D23) by sucrose density gradient centrifugation in zonal rotors. The membrane fractions retained tumour specific antigenic determinants and exhibited an increased antigenic activity over other subcellular membrane fractions, as defined by their capacity to quantitatively neutralize the membrane immunofluorescence staining of viable hepatoma D23 cells by antibody in tumour immune serum. In contrast, no antigenic activity was found to be associated with purified hepatoma D23 nuclei or nuclear membranes as evaluated by the in vitro antigen assay.The two methods described for the isolation of hepatoma D23 membranes have been developed for the large scale fractionation of tumour homogenates in order that further studies upon the nature and immunogenicity of membrane associated tumour specific antigens may be resolved using defined membrane preparations of increased antigenic activity. PMID- 4143272 TI - The effect of bleomycin and its combined effect with radiation on murine squamous carcinoma treated in vivo. AB - Many previous reports testify to the effectiveness of bleomycin as a drug for the clinical treatment of squamous carcinomata, and some radiotherapists have considered the possibility that an improved therapeutic ratio might be obtained by combined treatment with bleomycin and radiation. This consideration has been stimulated by recent reports of the effects of combined treatment with bleomycin using mammalian cells in vitro. Experiments are described here in which a murine squamous carcinoma has been used to obtain a survival curve for cells of tumours treated in vivo with single doses of bleomycin alone or in combination with radiation given before or after the drug. The survival curve for drug alone was a multicomponent curve with D(0) values of 0.1, 0.75 and 2.7 mg/kg. However, the results of the experiments with combined treatment showed no evidence of potentiation. PMID- 4143273 TI - The sensitivity to bleomycin of a solid mouse tumour at different stages of growth. PMID- 4143274 TI - Passive sensitization of guinea-pig skin in vitro for the antigen-induced release of anaphylactic mediators. PMID- 4143275 TI - Respiratory mast cells and basophiloid cells. I. Evidence that they are secreted into the bronchial lumen, morphology, degranulation and histamine release. PMID- 4143277 TI - Homogeneous immunoglobulins in sera of rhesus monkeys after lethal irradiation and bone marrow transplantation. PMID- 4143279 TI - The relationship of the P-K titre to the serum IgE level in patients with leprosy. PMID- 4143287 TI - [Surgical treatment of cervico-prostato-sphincteral dysuria in paraplegics]. PMID- 4143285 TI - Shared antigenic determinants between human brain and human T-cell line. PMID- 4143288 TI - [Multiple and simultaneous uro-urologic operations excluding lithiasis]. PMID- 4143289 TI - [Multiple and simultaneous operations on the urinary tract and adjacent organs. II. Urology and abdominal surgery]. PMID- 4143290 TI - [Prostatectomy in hematologic patients]. PMID- 4143291 TI - [Therapeutic problems posed by bladder tumor associated with prostatic adenoma]. PMID- 4143292 TI - Spontaneous cardiomyopathies in Chacma baboons. PMID- 4143293 TI - Haemodynamic basis for pericardiotomy as palliative treatment of idiopathic endomyocardiopathy. PMID- 4143294 TI - [A new test for the diagnosis of so-called seronegative rheumatoid arthritis]. PMID- 4143295 TI - [Algoneurodystrophic syndromes: 11 cases observed in a year]. PMID- 4143296 TI - Direct approach to the enumeration of structural proteins of the large ribosomal subunit of rat liver. PMID- 4143297 TI - Studies on proteins of animal ribosomes. XVIII. Reaction of ribosomes and ribosomal proteins with antibodies against ribosomal proteins. PMID- 4143298 TI - Morphology of the ribosomal 30S subparticle according to electron microscopic data. PMID- 4143299 TI - The structure of liver ribosomes. PMID- 4143300 TI - Effects of 5-azacytidine on hepatic polyribosomes and maturation of ribosomal RNA. PMID- 4143301 TI - Auditory discrimination and substitutions concerning the phonemes /s/ /l/ /r/ /rr/ /d/ in the speech disorders of dyslalic children. PMID- 4143302 TI - [Serum and synovial fluid levels of alpha-2-macroglobulin in rheumatoid arthritis]. PMID- 4143303 TI - [A case of Whipple's disease complicated by bilateral central scotoma]. PMID- 4143304 TI - Partial isolation of a membrane antigen which induces the formation of antibodies lethal to schistosomes cultured in vitro. PMID- 4143305 TI - Anaphylactic hyposensitization of rat mast cells in vitro by antigen. PMID- 4143306 TI - [Use of plastic adhesive to take cutaneous specimens]. PMID- 4143307 TI - Disturbed relationship of plasma-renin to blood-pressure in hypertension. PMID- 4143308 TI - Increased bilirubin levels in neonates after induction of labour by intravenous prostaglandin E2 or oxytocin. PMID- 4143309 TI - Surgery for cardiogenic shock. PMID- 4143310 TI - Death and coronary attacks in men after giving up cigarette smoking. A report from the Framingham study. PMID- 4143311 TI - Lymphocytotoxins in primary renal disease. PMID- 4143312 TI - Skin lesions, angio-oedema, and hypocomplementaemia. PMID- 4143313 TI - Simultaneous occurrence of soft-tissue sarcoma and parotid-gland tumours: A new syndrome? PMID- 4143314 TI - Temporary paralysis in childhood after influenza B. PMID- 4143315 TI - Treatment of parkinsonism with bromocriptine. PMID- 4143316 TI - An experiment in community mental health care. PMID- 4143317 TI - Editorial: Rapeseed oil revisited. PMID- 4143318 TI - Editorial: Fat embolism and hypoxaemia. PMID- 4143320 TI - Editorial: Training the basic doctor. PMID- 4143319 TI - Pre-hospital ventricular defibrillation. PMID- 4143321 TI - Editorial: Primary care of mental illness. PMID- 4143322 TI - Editorial: More from the adverse reactions register. PMID- 4143323 TI - Editorial: Out of mind? PMID- 4143324 TI - Anaemia. PMID- 4143325 TI - Urinary-tract infection. PMID- 4143326 TI - Diabetes. PMID- 4143327 TI - Sickle-cell disease. PMID- 4143328 TI - Epidemiology of cholera in Italy in 1973. PMID- 4143329 TI - Neural route of infection in viral diseases of the central nervous system. PMID- 4143330 TI - Letter: Immunochemical localisation of complement in intestinal mucosa. PMID- 4143332 TI - Letter: Screening for hypertension. PMID- 4143331 TI - Letter: Maternal smoking and immunity. PMID- 4143333 TI - Letter: Breast cancer and hypertension. PMID- 4143334 TI - Letter: Withdrawal of antihypertensive therapy. PMID- 4143335 TI - Letter: Cold-sensitive strain of Pseudomonas aeruginosa from urinary-tract infection. PMID- 4143336 TI - Letter: Bowie and Dick test for autoclaves. PMID- 4143337 TI - Letter: Skin wrinkling in cystic fibrosis. PMID- 4143338 TI - Letter: HL-A antigens in asymptomatic chronic HBAg carriers. PMID- 4143339 TI - Letter: HL-A antigens in leprosy. PMID- 4143340 TI - Letter: Ketamine-induced acidosis, fever, and creatine-kinase rise. PMID- 4143342 TI - Letter: Viability of skin flaps. PMID- 4143341 TI - Letter: Prolactin, prostaglandin, and bone pain of metastatic breast cancer. PMID- 4143343 TI - Letter: Iron and infection in the newborn. PMID- 4143344 TI - Letter: Identity of cervical dysplasias. PMID- 4143345 TI - Letter: Outbreak of Salmonella agona in Italy. PMID- 4143346 TI - Letter: Hepatoblastoma associated with an oral contraceptive. PMID- 4143347 TI - Letter: Oral contraceptives, plasma-lysolecithin, and platelet aggregation. PMID- 4143349 TI - Letter: "Anti-anti". PMID- 4143348 TI - Letter: Reappearance of intestinal gas cysts after oxygen treatment. PMID- 4143350 TI - Letter: Human placental lactogen and fetal abnormality in infants of diabetic mothers. PMID- 4143351 TI - Letter: Twinning and illegitimacy in C.N.S. defects. PMID- 4143352 TI - Letter: Influenza A in an isolated population in the Amazon. PMID- 4143353 TI - Letter: Malignant kwashiorkor. PMID- 4143354 TI - Letter: Malnutrition and school progress. PMID- 4143355 TI - Letter: Duration of breast-feeding. PMID- 4143356 TI - Letter: Staphylococcal infection in the newborn. PMID- 4143357 TI - Letter: Oral digitalisation. PMID- 4143358 TI - Letter: Immunocompetence in low-birth-weight infants after intrauterine malnutrition. PMID- 4143359 TI - Letter: Agarose and counterimmunoelectrophoresis. PMID- 4143360 TI - Letter: Abnormal coagulation and trauma. PMID- 4143361 TI - Letter: Endoscopic liver biopsy. PMID- 4143362 TI - Letter: Carcinoma of the colon and cholecystectomy. PMID- 4143363 TI - Letter: Serum-copper in Hodgkin's disease before and after herpes zoster. PMID- 4143364 TI - Letter: Chemotherapy of Hodgkin's disease. PMID- 4143365 TI - Letter: Methyl-cholanthrene-induced sarcomata in mice after immunisation with Corynebacterium parvum plus syngeneic subcellular membrane fractions. PMID- 4143366 TI - Letter: Otitis media due to ampicillin-resistant Haemophilus influenzae. PMID- 4143367 TI - Letter: Serum-gastrin, vitiligo, and achlorhydric atrophic gastritis. PMID- 4143368 TI - Letter: Muscular dystrophies. PMID- 4143369 TI - Letter: Costing equipment for epidurals. PMID- 4143370 TI - Dillwyn Evans. PMID- 4143371 TI - Mary Broadfoot Walker. PMID- 4143372 TI - Raymond Marcus McKenzie Pratt. PMID- 4143373 TI - Roland Anthony Bennett. PMID- 4143374 TI - Timothy Stephen Radcliffe. PMID- 4143375 TI - Harry Chapman Sinderson. PMID- 4143377 TI - Clinical problems of some bullous dermatoses. PMID- 4143376 TI - Linkage and rearrangement of genes encoding mouse immunoglobulin heavy chains. PMID- 4143378 TI - Inhibition of experimental allergic encephalomyelitis in rats severely depleted of T cells. AB - Lewis rats depleted of thymus-derived cells (B rats) failed to develop either experimental allergic encephalomyelitis or antibody against myelin basic protein. Lewis B rats reconstituted with 690 x 10(6) thymocytes developed experimental allergic encephalomyelitis and levels of antibody against myelin basic protein comparable to those of controls. The Lewis B rat model should be useful in the analysis of the role of thymus-derived cell populations and antibody in the induction of experimental allergic encephalomyelitis. PMID- 4143379 TI - Antihistamines block radiation-induced taste aversions. AB - When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions. PMID- 4143380 TI - The autoimmune status in graves' disease. PMID- 4143381 TI - Effect of beta adrenergic blocking on the arrhythmias following coronary ligation in rat. PMID- 4143382 TI - Effect of sublethal concentrations of the insecticides DDT, Abate and Sevin, applied to 3rd stage larvae of Culex pipiens molestus on certain biological aspects of the mosquito. PMID- 4143383 TI - Effect of sublethal concentrations of the insecticides DDT, Abate and Sevin applied to 3rd stage larvae of Anopheles pharoensis on malaria cycle in the adult mosquito. PMID- 4143384 TI - The complement system and nephritis. PMID- 4143385 TI - [Radio-opaque intravenous catheters. An unsuspected cause of iodine contamination]. PMID- 4143386 TI - [Detection and histochemical identification of lipoid enclaves in rat trophoblast between 15th and 20th day of gestation (author's transl)]. AB - Histochemical study of lipids in the allanto placenta of albino rats from the 10th to the 20th day of gestation permits the identification of lipoids enclaves in the trophoblastic cells. Their nature and topography show variations during the placenta evolution. Following a lipoid load, essentially acidic and evenly distributed both in the syncytium and in the giant cells (10th to 15th day), pigmented lipids appear. The latter are exclusively localized in the labyrinth and become preponderant at the 20th day, when the acidic lipid content has decreased extensively. The Autours discuss the nature of these pigmented lipoids and their relationship with the lipid metabolism of the placenta. PMID- 4143387 TI - [Lindane effects in several generations on the fertility and embryonic mortality levels, the hatchability, the egg production and the egg and chicken weight(author's transl)]. AB - The pulverization of Japanese Quail eggs with a solution of commercial Lindane has a repercussion on fertility, embryonic mortality, hatchability, egg production, eggs and Quail-Chickens weight (Studies in for generations). PMID- 4143388 TI - [Microbiology of leprosy. Behavior and staining affinities of Hansen's bacillus in leprous lesions]. PMID- 4143389 TI - Alpha-fetoprotein in the management of high-risk pregnancies. PMID- 4143390 TI - Management and prevention of erythroblastosis fetalis. PMID- 4143391 TI - [Surgical treatment of 106 pulmonary metastases]. PMID- 4143392 TI - Five-year follow-up of thyrotoxicosis treated with antithyroid drugs. PMID- 4143393 TI - Glycosaminoglycans and sialoproteins in skin aging. PMID- 4143394 TI - Clinical and experimental investigations on the effect of cytostatic drugs in psoriasis. PMID- 4143395 TI - Filarial infectivity rate of Culex pipiens molestus subjected to sublethal concentrations of insecticides Abate and Sevin and distribution of infective filaria larvae in mosquito body regions. PMID- 4143396 TI - In vitro studies of cell mediated immunity to human sarcomas. PMID- 4143397 TI - Skinning of cestodes of middle and large sizes for whole mounts. Technical note. PMID- 4143398 TI - [Alpha fetoproteins (AFP) in prenatal diagnosis of anencephalus and spina bifida. Resume and selection from current literature]. PMID- 4143399 TI - [In vitro studies of fibroblasts in myotonic dystrophy (author's transl)]. PMID- 4143400 TI - [Effect of specific donor gamma-globulin in experimental influenza infection. Report I]. PMID- 4143401 TI - [Antigenic properties of donor anti-influenza gamma globulin. Report 1. Indirect test of the degradation of mast cells of white rats and study of the antigenic properties of human gamma-globulin]. PMID- 4143402 TI - [Antigenic properties of donor anti-influenza gamma-globulina. Report 2. Clinico laboratory study of the sensitization properties of donor gamma globulin]. PMID- 4143403 TI - [Influence of anti-influenza gamma globulin on humoral immunity in acute respiratory viral infection in children]. PMID- 4143404 TI - [Improvement of the preparation of anti-influenza donor gamma-globulin. Report 1. Experience in the cultivation of the killed influenza vaccine, purified and concentrated by means of gradient centrifugation]. PMID- 4143405 TI - [Improvement of the preparation of anti-influenza donor gamma globulin. Report 2. Testing of the immunogenicity of the killed vaccine, purified and concentrated by means of gradient centrifugation]. PMID- 4143406 TI - [Cholestatic hepatitis induced by the prolonged administration of nalidixic acid (case report)]. PMID- 4143407 TI - [Determination of serum levels of alpha-fetoprotein in some morbid conditions]. PMID- 4143408 TI - Retrograde axonal transport of horseradish peroxidase in rats forebrain. PMID- 4143409 TI - Afferents to the rat caudoputamen studied with horseradish peroxidase. An evaluation of a retrograde neuroanatomical research method. PMID- 4143410 TI - The timing of the earliest motor innervation to the hind limb bud in the Xenopus tadpole. PMID- 4143411 TI - The retrograde axonal transport of nerve growth factor. AB - A retrograde axonal transport of nerve growth factor (NGF) from the adrenergic nerve terminals in the mouse iris to the cell bodies of postganglionic sympathetic neurones in the superior cervical ganglion has been demonstrated. After injection of iodinated nerve growth factor (125I-NGF) into the anterior eye chamber there was a relatively rapid accumulation of radioactivity in the superior cervical ganglia on both injected and non-injected sides, as was the case after subcutaneous injection. However, 4 h after intraocular injection a preferential accumulation of radioactivity became apparent in the superior cervical ganglion on the injected side, and this difference between the ganglia on injected and non-injected sides gradually increased to a maximum at 16 h. Transection of the postganglionic adrenergic fibres as well as the prior intraocular injection of colchicine abolished the preferential accumulation of 125I-NGF in the superior cervical ganglion of the injected side, whereas the destruction of adrenergic nerve terminals by 6-hydroxydopamine did not impair the preferential accumulation. It is concluded that the retrograde axonal transport of NGF, which was estimated to take place at a rate of about 2.5 mm/h, depends on a colchicine-sensitive mechanism as does the orthograde rapid axonal transport. However, the uptake of NGF may not only take place from the nerve terminals but also from the preterminal parts, as has been shown in other studies with horseradish peroxidase. Autoradiographic studies strongly supported the existence of a retrograde transport by showing a clear localization of radioactivity in a small number of neurones in the superior cervical ganglion on the injected side, whereas on the non-injected side there was only a diffuse distribution of radioactivity throughout the ganglion. PMID- 4143412 TI - A microelectrophoretic delivery technique for use with horseradish peroxidase. PMID- 4143413 TI - [Value of the study of alpha-1-fetoprotein in obstetrics]. PMID- 4143414 TI - [High levels of alpha-1-fetoprotein in the amniotic fluid: index of fetal death in utero]. PMID- 4143415 TI - [Amniotic alpha-1-fetoprotein in fetal death in utero]. PMID- 4143416 TI - [Coagulation disorders in gynecology and obstetrics. 2. Pathologic coagulation and its treatment]. PMID- 4143417 TI - [Fetal extrasystole. Diagnostic, pathogenic, and prognostic considerations]. PMID- 4143418 TI - [Antenatal diagnosis of fetal sex by examination of free cells in the amniotic fluid stained by the Papanicolaou method]. PMID- 4143419 TI - [Control of some histochemical properties of tissues embedded in araldite]. PMID- 4143420 TI - [Evidence of acid mucopolysaccharides in semifinal and final sections by means of staining with alcian blue]. PMID- 4143421 TI - [Histochemical research on human corneal stroma during prenatal development]. PMID- 4143422 TI - The Feulgen-DNA content in human individual metaphasic chromosomes. PMID- 4143423 TI - [Stable sudanophilia and labile (lysochronic) sudanophilia in human normal and pathological granulocytes]. PMID- 4143424 TI - [Spectrofluorometric and cytochemical research on biogenic amines in the cerebral ganglion of Helix pomatia]. PMID- 4143425 TI - [Some histochemical characteristics of cells from the myenteric plexus existence of histaminergic tryptaminergic and dopaminergic cells and fibers in the metasympathetic system]. PMID- 4143426 TI - A complement fixation test for the detection of alpha-feto-protein in the diagnosis of primary liver cancer. PMID- 4143427 TI - Structures and syntheses of aminoglycoside antibiotics. PMID- 4143428 TI - Biochemical mechanism of resistance to aminoglycosidic antibiotics. PMID- 4143429 TI - [Analysis of soluble antigens of the human striated musculature. II. Immunochemistry studies]. AB - Human skeletal muscle was extracted at pH 7 and the supernatant of entrifugation at 100 000 X g for 1h examined with different immunological methods. In these studies the following anti-sera absorbed with human serum proteins were used: anti-muscle, anti-heart, anti-brain, anti-kidney, and anti-pancreas serum. Further anti-muscle serum absorbed with human serum and liver extract was applied. At least 10 antigens typical for skeletal muscle could be detected with these different sera. One of the antigens with great probability is specific for skeletal muscle. Its electrophoretical mobility was 3,75-105cm2/V sec. Two antigens revealed enzymatic activities. PMID- 4143431 TI - Molecular architecture of human chromosomes. PMID- 4143430 TI - [New information in the study of synovial fluid]. PMID- 4143432 TI - Atmospheric carbon monoxide. PMID- 4143433 TI - Production of instructional messages for education in the health professions: a role-integrated approach. PMID- 4143435 TI - What's available? Is it any good? How do you know? PMID- 4143434 TI - Use of television and film in continuing education in the health sciences. A nine year experience. PMID- 4143436 TI - Visual communication and continuing medical education. PMID- 4143437 TI - Delivery of papers at scientific meetings. PMID- 4143438 TI - Mastery learning, minicourses and multimedia instruction in anatomy. PMID- 4143439 TI - Arteriovenous hemangioma (arteriovenous shunt). A clinicopathological and histochemical study. PMID- 4143440 TI - Light and electron microscopic study of Riehl's melanosis. Possible mode of its pigmentary incontinence. PMID- 4143441 TI - [Prevention of feto-maternal immunization]. PMID- 4143442 TI - [Critical study of the results of an application of preventive treatment taking into account the systematic evaluation of feto-maternal hemorrhage]. PMID- 4143443 TI - [Usefulness of periodic and regional evaluation in prevention of Rhesus isoimmunization: remarks on North American experiences]. PMID- 4143444 TI - [Prevention of feto-maternal isoimmunizations. Organization in the Marseilles region]. PMID- 4143445 TI - [Serum prolactin and gonadotropins during the normal menstrual cycle and during oral contraceptives]. PMID- 4143446 TI - [Radioimmunologic determination of alpha fetoproteins in the maternal serum during pregnancy, labor and post-partum period]. PMID- 4143447 TI - [Radioimmunologic determination of alpha fetoprotein. iv. Applications to obstetrics, and preliminary study of Rhesus feto-maternal incompatibilities]. PMID- 4143448 TI - A study of adverse reactions to high dosage intermittent thiacetazone. PMID- 4143449 TI - Serum concentrations and antituberculosis activity of thiacetazone. PMID- 4143450 TI - Treatment of isoniazid-resistant pulmonary tuberculosis with ethambutol, rifampicin and capreomycin: a co-operative study in England and Wales. PMID- 4143451 TI - The sensitivity to thiacetazone of tubercle bacilli isolated from patients with pulmonary tuberculosis in Sri Lanka. PMID- 4143452 TI - A pilot study of two regimens of intermittent thiacetazone plus isoniazid in the treatment of pulmonary tuberculosis in East Africa. PMID- 4143453 TI - Notes on the Ziehl-Neelsen staining of sputum. PMID- 4143454 TI - A controlled clinical trial of the role of thiacetazone-containing regimens in the treatment of pulmonary tuberculosis in Singapore: second report. PMID- 4143455 TI - Immunoglobulins in liver diseases. PMID- 4143456 TI - The suppressive effect of antibodies on cellular cooperation. AB - 1) The primary and secondary anti-carrier antibody responses were markedly suppressed by the passively administered anti-carrier antibody but not by the anti-hapten antibody. 2) The primary and secondary anti-hapten antibody responses were suppressed not only by the passively administered anti-hapten antibody but also by the anti-carrier antibody. 3) Passively administered 3.5S fragments of the anti-carrier antibody selectively suppressed the anti-carrier antibody response but had no effect on the capacity of carrier-specific helper T cells to facilitate the anti-hapten antibody response. 4) Passively administered anti carrier antibodies did not suppress the development of carrier-specific helper T cells but suppressed B memory cells specific for the haptenic group as well as the carrier determinant. PMID- 4143457 TI - Potential dilemma: the methods of meeting automotive exhaust emission standards of the clean air act of 1970. AB - This review attempts to provide an overview of the interconnected industrial changes associated with compliance with the exhaust emission standards of the Clean Air Act of 1970. To understand the complex nature of air pollution problems, Federal legislation, and compliance with this legislation requires an understanding of automotive technology, petroleum refining, atmospheric chemistry and physics, economics, and public health. The endeavors of all of these different areas impinge to a greater or lesser extent on the final response to the Clean Air Act which is designed to safeguard public health. This overview begins by examining gasoline refinery practice and gasoline composition. Included in this discussion are average values for trace contaminants in gasoline, and an explanation of the function of the many gasoline additives. Next, exhaust emissions are characterized, average values of exhaust components given, and a summary of important atmospheric air pollution reactions presented. Emission control devices and sulfate emissions from these devices are described. This is followed by a complete discussion of methyl cyclopentadienyl manganese tricarbonyl, a substitute antiknock for tetraethyllead. In the event TEL is legally banned from gasoline, or removed because it poisons the catalytic muffler surface, this manganese antiknock is the most efficaous replacement. In this discussion, the adverse health effects caused by exposure to manganese oxide particulates, the possible exhaust emission products from this additive, are examined in detail. The review concludes with comments on automotive engine and gasoline composition redesign as an approach to automotive air pollution. PMID- 4143458 TI - [Why audio-visual sessions? For whom?]. PMID- 4143459 TI - [Qualitative and critical study of the pressure quadrant of the alveolar bone after orthodontic displacement]. PMID- 4143461 TI - The surgical treatment of extracranial arterial occlusion. PMID- 4143460 TI - Inhibitors of nucleic acid synthesis: biophysical and biochemical aspects. PMID- 4143462 TI - Cavernous sinus venography by transbasilic catheter technique. PMID- 4143463 TI - Diagnostic value of stationary potential measurement in head injuries. PMID- 4143464 TI - Significance of vascular notching of optic nerves and chiasm on visual disturbance. PMID- 4143465 TI - Malignant primary meningeal tumors. PMID- 4143466 TI - Stiffness of cerebral arteries--its role in the pathogenesis of cerebral aneurysms. PMID- 4143467 TI - Dural calcification from the neurosurgical point of view. PMID- 4143468 TI - Cerebrovascular Moyamoya disease. IIIrd report--the study on the aging of the perforating branches and the possibility of collateral pathway. PMID- 4143469 TI - Anterior communicating artery aneurysm not visualized by angiography. Report of two successfully operated cases. PMID- 4143470 TI - The place of intra-arterial methylene blue vital stain and histochemistry of acetylcholinesterase in experimental neurology and psychiatry. PMID- 4143471 TI - Effects of metrizamide on silver staining of aortic endothelium. A comparison with metrizoate media in rats. PMID- 4143472 TI - Mitochondrial uptake of calcium ions and the regulation of cell function. PMID- 4143473 TI - Immunoglobulin production in B-lymphocytes: synthesis of the membrane-bound receptor and the secreted serum glycoprotein immunoglobulin M. PMID- 4143474 TI - A comparative analysis of extrinsic fluorescence in nerve membranes and lipid bilayers. PMID- 4143475 TI - Clinical use of radiation sensitizing agents. PMID- 4143476 TI - [Clinical evaluation of indium bleomycin in the scanning of neoplasm]. PMID- 4143477 TI - [Carcino-fetal antigens in gastroenterology]. PMID- 4143478 TI - [Presence of serum alpha fetoprotein in 4 cases of primary digestive cancers other than hepatomas]. PMID- 4143479 TI - [Practical value of alpha fetoprotein in the diagnosis and postoperative surveillance of embryonic tumors of the testis]. PMID- 4143482 TI - A new way to demonstrate the capillary beds at light microscopy. PMID- 4143480 TI - [Existance of alpha 1-fetoprotein in the absence of hepatoma]. PMID- 4143481 TI - The immune system: a web of V-domains. PMID- 4143483 TI - The use of tannin-iron method as a nervous system general stain technique. PMID- 4143485 TI - Characterization of a long-term suspension culture of the LLC-MK monkey kidney cell line. PMID- 4143486 TI - The production of markers by bronchogenic carcinoma: a review. PMID- 4143484 TI - To disaggregate or not to disaggregate injury and cell disaggregation, transient or permanent? PMID- 4143487 TI - Radiotherapy of bronchogenic carcinoma. PMID- 4143488 TI - The role of chemotherapy in the treatment of lung cancer. PMID- 4143489 TI - In vitro testing in tumor immunotherapy. PMID- 4143490 TI - Serologic characterization of selected bluetongue virus strains from the United States. PMID- 4143491 TI - The control of outbreaks of leptospriosis in beef cattle by simultaneous vaccination and treatment with dihydrostreptomycin. PMID- 4143492 TI - Antigenic variation of Venezuelan strains of foot and mouth disease viruses. PMID- 4143493 TI - [Separation and characterization of lymphocytes]. PMID- 4143494 TI - [Morphological study of the so-called monostotic fibrous dysplasia: pathogenetic criteria]. PMID- 4143495 TI - The dental school and the university: a case for unification. PMID- 4143496 TI - The Pennsylvania approach. PMID- 4143498 TI - Basic sciences in the DMD cirriculum. PMID- 4143497 TI - Basic sciences at Pennsylvania. Continuity and commitment. PMID- 4143499 TI - A PDJ poll. A profile of student interest in research. PMID- 4143500 TI - Opportunities for research (a guide to obtaining summer research). PMID- 4143501 TI - COHR-what is it, where is it going? PMID- 4143502 TI - "SEM" becomes part of dentistry's lingo. PMID- 4143503 TI - Biosynthesis of collagen in the periodontal ligament. PMID- 4143504 TI - A technique for replacement of anterior teeth in the adolescent patient; a case presentation. PMID- 4143505 TI - The externist or how to get the devil out of the dental school. PMID- 4143506 TI - The dentist: a multidimensional man. PMID- 4143507 TI - "The forest through the trees...". PMID- 4143508 TI - [1st experience with the use of audiovisual programs in the teaching of anatomy]. PMID- 4143509 TI - [Biochemical syndrome of synovial fluid after radiation synovectomy using yttrium 90-Y]. PMID- 4143510 TI - [The experience of bleomycin treatment for oral cancer with special reference to unoperated cases]. PMID- 4143511 TI - The effect of preoperative combined bleomycin and radiation therapy in hilar bronchial carcinoma. PMID- 4143512 TI - New techniques in the diagnosis of acute pulmonary embolism. PMID- 4143513 TI - [Urethral stenosis after prostatectomy for adenoma. Clinico-radiological study]. PMID- 4143514 TI - [Silhouette projection as an illustrative material in education]. PMID- 4143515 TI - The comprehensibility of dental health literature. PMID- 4143516 TI - Structural features of streptolysin O. PMID- 4143517 TI - The diagnostic value of amniocentesis. PMID- 4143518 TI - [An electron-microscopic observation of tissue changes affected by anticancer agents. 1. Effects of bleomycin on the oral mucous epithelium of rats (author's transl)]. PMID- 4143519 TI - [Study for medicinal penetration in dental tissue (author's transl)]. PMID- 4143520 TI - [Pedodontics and other problems of dentistry in Europe and America (author's transl)]. PMID- 4143521 TI - [Film in color, total prosthesis of Professor Schreinemakers]. PMID- 4143522 TI - [Catanzaro-Guimaraes polycrome stain for the demonstration of periodontal structures during the regeneration process (author's transl)]. PMID- 4143523 TI - [Observations on the control of P megistus with BHC in an infested area of the State of Bahia, Brazil]. PMID- 4143524 TI - [Group work--continuing education saline injection?]. PMID- 4143525 TI - Trichomonas vaginalis, a pathogen of prostatitis. PMID- 4143526 TI - [Developmental neurology in children. 1st Symposium on Pediatric Neurology. Prague]. PMID- 4143527 TI - [Disorders of lateralization caused by severe organic brain damage]. AB - The decisive period of the development of dominance is in the fourth year. Aphasic disturbances in younger children therefore have as their prerequisite bilateral lesions, it being only after this period that aphasias may be observed to be associated with unilateral cerebral lesions. Up to the fourth year of life it is, therefore, possible for unilateral cerebral lesions to be relatively easily compensated by a "change of dominance". PMID- 4143528 TI - [Speech disorders in childhood]. AB - The paper discusses the individual childhood speech disorders: articulation, phonation, and rhythm disorders as well as the dysfunction of speech. In addition to the causes of retarded speech development, the authors discuss especially childhood aphasias. As an all-important characteristic feature of childhood aphasia they give emphasis to the rapid regression of speech disorders as well as to the absence of a dependence upon the localization of the lesion. They also discuss the existing nomenclature. Also discussed were the congenital speech disorders for which they suggest the term "congenital abnormality of speech reception and expression". PMID- 4143529 TI - [Determination of poisoning threshold based on the electroencephalogram using the chi-square method]. PMID- 4143530 TI - Deaths from appendicitis and appendicectomy. PMID- 4143531 TI - Recombinant influenza-A viruses as live vaccines for man. Report to the Medical Research Council's Committee on Influenza and other Respiratory Virus Vaccines. AB - The infection of volunteers with five hybrid influenza-A viruses is described. Four of these were produced in Great Britain by recombining an Ao virus, non infective for man, with a wild Hong Kong like strain. The fifth was the American recombinant, X-31, derived from similar parents and widely used in the manufacture of killed vaccines. All five viruses had the haemagglutinin and neuraminidase of A2/Hong Kong/68. Two of the viruses were not attenuated and induced symptoms of clinical influenza. The other three were appreciably attenuated and were infective and antigenic. It seems that recombination is a rapid and effective way of producing live vaccine viruses to specification. It is also the quickest known method of attenuation. PMID- 4143532 TI - Controlled trial of azathioprine in Crohn's disease. AB - The effect of azathioprine in patients with active Crohn's disease has been evaluated in a double-blind cross-over trial. Fifteen patients were treated with both azathioprine and placebo: only two improved while on azathioprine, six got worse, and in seven there was no change. The drug seemed to be the cause of deterioration in two of the patients. Although the drug may be of some value in a few patients, it should be used with caution and only when other measures have failed. PMID- 4143533 TI - Disinfection of the umbilicus for abdominal surgery. AB - Bacteriological investigation of the adult umbilicus showed that it is much more profusely colonised by bacteria than the rest of the abdominal skin. Routine preoperative treatment with alcoholic chlorhexidine solution did not disinfect the umbilicus satisfactorily. Better results were achieved by disinfection with povidone iodine followed by alcoholic chlorhexidine. PMID- 4143534 TI - Separation of rubella IgM, IgA, and IgG antibodies by gel filtration on agarose. AB - Identification of the immunoglobulin classes of rubella antibodies is the only reliable tool for the diagnosis of a recent primary infection with rubella within 6-8 weeks of infection. Gel filtration permits the separation of IgM and IgA antibodies, both characteristic for a recent infection, from persistent rubella IgG antibody (which indicates pre-existing immunity). Gel filtration on agarose offers advantages over the other methods for separating immunoglobulin classes. Fractionation of specific rubella antibodies is important not only in all cases where a serum sample was taken too late and a rise of antibody titre missed, but also in cases with significant antibody rise to distinguish a secondary immune response after rubella reinfection. PMID- 4143535 TI - Atherosclerosis and vitamin C. AB - Following the chance observation that the author's serum-cholesterol could be varied between 140 and 230 mg. per 100 ml. by increasing the vitamin-C intake or by lowering it, a study was undertaken in healthy individuals and in patients with atherosclerosis. In healthy people under the age of 25, cholesterol levels tended to fall when 1 g. of vitamin C per day was added to an otherwise normal diet. In older people, no consistent pattern of serum-cholesterol change was seen, but in patients with a history of atherosclerosis, most of whom were on clofibrate and/or anticoagulants, the serum-cholesterol increased in the weeks when vitamin-C supplements increased in the weeks when vitamin-C supplements were given. It is suggested that this rise in serum-cholesterol is caused by mobilisation of the arterial cholesterol. PMID- 4143536 TI - Skin cancer and immunosuppression. AB - 7 (14%) out of 51 kidney-allograft recipients developed a total of 19 malignant skin tumours four to forty-five months after transplantation. Immunosuppressive treatment, known to be associated with an increased risk of development of tumours of lymphoreticular type, also enhances the occurrence of squamous-cell carcinoma. Under the influence of immunosuppression cutaneous hyperkeratoses more rapidly evolve into squamous-cell carcinoma, multiple skin cancers occur in some patients, and keratoacanthoma is not only more frequent but also prone to early recurrence. PMID- 4143537 TI - Effects of sodium intake on inherited hypertension in the rat. AB - The effect of sodium chloride intake on systolic blood-pressure was studied in genetic hypertensive Wistar rats. In these animals hypertension can develop on a sodium-"free" diet, but the height to which the blood-pressure rises is related to the sodium intake; increasing the amount of potassium in the diet promotes sodium excretion and ameliorates the hypertension. It is suggested that this form of inherited hypertension may be determined by two different sets of autosomal alleles only one of which is sodium-dependent. PMID- 4143538 TI - Contribution of fetal/maternal incompatibility to aetiology of pre-eclamptic toxaemia. AB - Data are presented on an association between toxaemia of pregnancy and consanguinity of patients, seen at a Turkish hospital, and their husbands. Women with toxaemia were less frequently related to their husbands than those with no signs of pre-eclampsia. The relationship between toxaemia in twin pregnancies and the sexes of the twin pairs from four sources are examined. In all four pre eclampsia seems to be more common in unlike-sex than in like-sex twin pregnancies, and, by extension, to be more common in dizygous than in monozygous twin pregnancies. PMID- 4143539 TI - A "new" disorder of isoleucine catabolism. AB - A disorder of isoleucine catabolism was found in a child with intermittent metabolic acidosis. The block occurs at the stage of propionate synthesis, and two intermediates--alpha-methylacetoacetate and alpha-methyl-beta-hydroxybutyrate -accumulate. The condition is apparently inherited. PMID- 4143540 TI - Insensitivity of respiratory centre to carbon dioxide in the Enga people of New Guinea. AB - The ventilatory response to a rising carbon-dioxide (CO2) tension has been determined in healthy New Guinea natives using a new apparatus which was developed for field-work. The response in New Guineans did not vary greatly between individuals, in contrast to the finding in healthy Caucasians. In all twelve New Guinean subjects the indices of response fell in the lowest range of Caucasian response. These findings suggest that genetic and racial factors account for the marked variability of the ventilatory response to CO2 in normal man. It is suggested that inherited insensitivity of the respiratory centre in New Guineans (and in some Caucasians) leads to unusually severe disturbances of blood gases in chronic lung disease. This hypothesis is supported by published data relating arterial PCO2 and the severity of airways obstruction in New Guineans. PMID- 4143541 TI - Newborn-infant heater. PMID- 4143542 TI - A palatal incision. PMID- 4143543 TI - The coronary arteriogram. PMID- 4143544 TI - Aetiology of vitiligo. PMID- 4143545 TI - Evolution by gene and chromosome duplication. PMID- 4143546 TI - Occupational health: a new/old bill. PMID- 4143547 TI - Breakthrough. PMID- 4143548 TI - Reorganising the delivery and payment of health care in the United States. PMID- 4143549 TI - Health care in America--privilege or right? PMID- 4143550 TI - What priorities for health? PMID- 4143551 TI - Case-fatality of hyperplasia of the prostate in two teaching and three regional board hospitals. AB - Mortality of hyperplasia of the prostate, as in many common conditions, is higher in the regional board than the teaching hospitals of England and Wales. 932 men with simple hyperplasia of the prostate consecutively admitted to two teaching and three regional-board hospitals have been studied. There were 5 deaths among 556 men admitted from the waiting-list, and negligible variation between hospitals. Among the 376 unplanned emergency admissions were 35 deaths, 26 of them in 71 men who did not have prostatectomy. Unplanned admissions, especially those not operated on, were older than the rest and mostly in acute retention, and many also had cardiovascular and other disease. 78% of the admissions to two of the regional-board hospitals were unplanned; the operation-rate on these men was generally low and case-fatality among them was 14%. In contrast, only 22% of the admissions to the two teaching hospitals were unplanned, nearly every case was operated on, and the case-fatality was 4.3%. These two regional-board hospitals with relatively small resources were carrying more than their share of the most difficult cases. A national survey to assess the treatment of hyperplasia of the prostate is now indicated, but it is time the National Health Service gathered this kind of information routinely. PMID- 4143552 TI - Cerebral atrophy in young cannabis smokers. PMID- 4143553 TI - Possible role of saliva in the sudden infant-death syndrome. PMID- 4143554 TI - Aspirin-induced hypoglycaemia in a patient on haemodialysis. PMID- 4143555 TI - Precapillary bypass and sudden infant death. PMID- 4143556 TI - The social fate of the amputee. PMID- 4143558 TI - Iron losses and iron requirements. PMID- 4143557 TI - Is selenium a teratogen? PMID- 4143559 TI - Stomach cancer after gastric operations for benign conditions. PMID- 4143560 TI - Effect of alcohol on glucose tolerance. PMID- 4143561 TI - Water intoxication in beer-drinkers. PMID- 4143562 TI - Neutropenia in people of African origin. PMID- 4143564 TI - Tests for toxoplasmosis. PMID- 4143563 TI - Fetal karyotype from amniotic cells without culturing. PMID- 4143565 TI - Childhood cancer following obstetric radiography. PMID- 4143566 TI - Drug resistance in Trichomonas vaginalis. PMID- 4143567 TI - Aetiology of retrograde amnesia. PMID- 4143568 TI - Identification of thymic-dependent lymphocytes. PMID- 4143569 TI - Fusidic acid in psoriasis. PMID- 4143570 TI - Glycerol in acute cerebral infarction. PMID- 4143571 TI - Thymolymphatic deficiency and depression of cell-mediated immunity in protein calorie malnutrition. PMID- 4143572 TI - Interaction between warfarin and phenformin. PMID- 4143573 TI - Plasma-zinc concentration in patients with bronchogenic cancer. PMID- 4143574 TI - Bromism. PMID- 4143575 TI - Infiltration of adrenaline before thyroidectomy. PMID- 4143576 TI - Low-dose combination chemotherapy of disseminated human neoplasms. PMID- 4143577 TI - Antenatal detection of Hurler's syndrome. PMID- 4143579 TI - When to remove the I.U.D. PMID- 4143578 TI - Lithium and mitotic index. PMID- 4143580 TI - Hospital siting and patient visiting. PMID- 4143581 TI - B lymphocytes in macroglobulinaemia. PMID- 4143582 TI - Electrical safety in hospitals. PMID- 4143583 TI - Sex ratio in hyperphenylalaninaemia. PMID- 4143584 TI - Tests for porphyria. PMID- 4143585 TI - Screening test for Y chromosome in newborn using urinary epithelial cells. PMID- 4143586 TI - Effects of contraceptive hormone preparations on the fine structure of the endometrium. PMID- 4143587 TI - Oral contraceptives and hypertension. PMID- 4143588 TI - Early and intensive therapy of intravascular coagulation in acute liver failure. AB - Four consecutive patients, three with fulminant hepatic failure and one with a severe relapse of serum hepatitis, who showed evidence of intravascular coagulation, were treated intensively with heparin and fresh frozen plasma. Rapid correction of the coagulation disturbance was achieved, and all four patients recovered completely. The necessity for starting such treatment early in the course of the disease and before the onset of major gastrointestinal bleeding is stressed, and it is suggested that intravascular coagulation may act as an intermediary in the pathogenesis of the hepatic necrosis. PMID- 4143589 TI - Sexual function following aortoiliac reconstruction. AB - Impotence due to atherosclerotic disease of the aorta and iliac arteries presents as failure to achieve erection. Sterility after aortoiliac reconstructive surgery is more common and presents as inability to ejaculate. If the superior hypogastric sympathetic plexus (presacral nerve) is preserved, sexual function can be maintained in 90% of cases. PMID- 4143590 TI - Cerebral atrophy in young cannabis smokers. AB - Evidence of cerebral atrophy was demonstrated by air encephalography in ten patients with histories of consistent cannabis smoking over a period of 3-11 years. The average age of the patients was 22 years; all were males. Amphetamines and lysergide (L.S.D.) had also been taken, but in much smaller amounts. Measurements of the lateral and third ventricles were significantly different from those in thirteen controls of a similar age-group. PMID- 4143591 TI - New antigen-antibody system in Australia-antigen-positive hepatitis. AB - After detergent treatment the 42 nm. Dane particles from the sera of patients with serum hepatitis separate into an outer coat of Australia antigen (Au-Ag) and an inner spherical 27 nm. diameter component resembling a rhinovirus. Antibody in post-hepatitic serum reacted with the inner component (but not with the outer) to yield aggregates resembling those seen in the liver of patients with serum hepatitis. Antibody to Au-Ag was not detected, before or after the attack of hepatitis. It is suggested that, in an attack of serum hepatitis, Au-Ag antibody develops but is subsequently cleared; antibody against the inner Dane component, however, persists. PMID- 4143592 TI - Abnormal insulin response in patients with small-vessel disease. AB - The insulin response to a glucose load has been investigated in twenty-five patients with small-vessel disease (ischaemic lesions of toes or feet in the presence of foot pulses). The clinical presentation was similar to that of juvenile diabetic microangiopathy, but in small-vessel disease there was no glucose intolerance. Unexpectedly in the patients with small-vessel disease there was no striking insulin secretion response to the stimulus of a glucose load. Controls increased their circulating insulin levels on average sixfold over fasting levels after 50 g. oral glucose: all the small-vessel-disease patients had increases of less than three times their fasting levels, and nine of them had completely flat curves throughout the test. Tolbutamide also did not stimulate insulin secretion. The refractory state of these patients' responses to the normal stimulus of insulin output has similarities to the picture in juvenile diabetes mellitus and may be important in the aetiology of the small-vessel lesions. PMID- 4143593 TI - Insulin response to glucose in patients with peripheral vascular disease, arteritis, and Raynaud's phenomenon. AB - Twenty-three patients with peripheral vascular disease due to atheromatous blocks in large vessels, four patients with arteritis, and twenty patients with Raynaud's phenomenon were tested for insulin response to glucose. (In an earlier investigation patients with small-vessel peripheral vascular disease did not secrete insulin in response to a glucose load--a previously unreported finding.) Insulin output after glucose in patients with atheromatous blocks in large peripheral arteries fell into three categories: (1) normal glucose tolerance and insulin output, the insulin rise (peak/basal ratio) comparing well with the rise in controls; (2) carbohydrate intolerance with a prediabetic pattern of glucose tolerance test, and raised circulating insulin levels both fasting insulin and after glucose, so that the insulin rise was lower than normal; or (3) the flat insulin responses after glucose that had been noted in small-vessel disease with normal glucose tolerance. Thus in these twenty-three patients with large-vessel blocks presenting with peripheral vascular disease the high and late insulin secretion after glucose reported by other workers for patients with atheroma could not be confirmed. High but not delayed insulin peaks were seen after a glucose stimulus in some patients with arteritis and with Raynaud's phenomenon. PMID- 4143594 TI - External method for detection of fetal breathing in utero. AB - An ultrasonic technique for detecting fetal breathing in utero has been developed using chronic fetal lamb preparations, and has been used successfully in pregnant women. PMID- 4143595 TI - Depression of immunological function in patients treated with phenytoin sodium (sodium diphenylhydantoin). AB - 63 patients on long-term oral therapy with phenytoin sodium (sodium diphenylhydantoin) were screened for abnormalities of immunological function. They were compared with 92 controls and 28 patients with lymphoma. Depression of cellular or humoral immunity, or both, was found in a significant number of phenytoin-treated and lymphoma subjects. Phenytoin therapy was associated with low immunoglobulin A (21%), failure of antibody response to Salmonella typhi antigen (9%), absence of delayed hypersensitivity (D.H.S.) to three common skin test antigens (22%), and depression of in-vitro lymphocyte transformation by phytohaemagglutinin (27%). Lymphoma patients manifested low IgM (22%), and inability to make antibody to S. typhi (11%) and to tetanus toxoid (21%). D.H.S. was absent in 36%; lymphocyte transformation was depressed in 17%. Abnormal lymphocyte transformation did not correlate with depression of cellular or humoral immunity in either group. PMID- 4143596 TI - Antecubital venepuncture in neonates. PMID- 4143597 TI - Instrument for sampling ovarian surface cells at laparoscopy. PMID- 4143598 TI - Autoclave which sterilizes with highly purified steam for tissue-culture laboratories. PMID- 4143599 TI - How safe is abortion? PMID- 4143600 TI - Cannabis encephalopathy? PMID- 4143601 TI - Research and the government. PMID- 4143602 TI - Australia antigen. PMID- 4143603 TI - Cromoglycate in asthma and hayfever. PMID- 4143604 TI - More on S.M.O.N. PMID- 4143605 TI - Sensory deprivation. PMID- 4143607 TI - Effects of the abortion law, 1967, on a gynaecological unit. AB - In the United Kingdom the more liberal attitude towards abortions engendered by the 1967 Act has increased the work of a gynaecological unit at Salford, Lancashire, by about 10%. In 1964-65 there were 15 therapeutic abortions, and in 1969-70 the number had increased to 447. The increased demand has been catered for by a reduction of stay in gynaecological patients: in fact, the "through-put" has increased and the waiting-list diminished. The increased work-load on the blood transfusion service has been slight, and on the credit side there has been a reduction in the numbers of septic abortions. The major problem has been in the outpatient department, since these cases are time-consuming and it is difficult to make a fair and impartial decision. PMID- 4143606 TI - Legal abortion: a critical assessment of its risks. AB - A review of the methods used and the results obtained in 1182 legal abortions in one teaching hospital confirms that termination of pregnancy, even in the early weeks, is neither simple nor safe. Nearly 17% of patients lost more than 500 ml. of blood and 9.5% required transfusion. Cervical lacerations occurred in 4.2% and the uterus was perforated in 1.2%. All the perforations were associated with the technique of vacuum aspiration. Emergency laparotomy was required for 6 patients and hysterectomy was twice necessary to save life. Pyrexia of 38 degrees C or more persisting for longer than 24 hours occurred in 27%. Peritonitis developed in 14 patients, with paralytic ileus in 7, and 6 others had septicaemia. No patient died. The need is stressed for a wider appreciation of the risks involved in allowing certain pregnancies to continue and those associated with their termination, irrespective of the method used. Methods of reducing certain of these risks are indicated. PMID- 4143608 TI - Treatment and prevention of sickle-cell crisis. PMID- 4143610 TI - Regression of neuroblastoma. PMID- 4143609 TI - Mechanism for the high incidence of sickle-cell crisis in the tropical cool season. PMID- 4143611 TI - Treatment after exposure to cold. PMID- 4143612 TI - Urinary-tract infection and low-dose nitrofurantoin. PMID- 4143613 TI - Urinary infection by coagulase-negative staphylococci. PMID- 4143614 TI - Oesophageal candidiasis and carcinoma of the oesophagus. PMID- 4143615 TI - Intravascular changes in the retina during open-heart surgery. PMID- 4143616 TI - Smoking and neuroticism. PMID- 4143617 TI - Analgesic abuse. PMID- 4143618 TI - Lung cancer among populations having lung irradiation. PMID- 4143620 TI - Nitroblue tetrazolium test in asthma and dysgammaglobulinaemia. PMID- 4143619 TI - Goodpasture's syndrome. PMID- 4143621 TI - Aid for the adolescent. PMID- 4143622 TI - Myelo-optic neuropathy induced by clioquinol in animals. PMID- 4143623 TI - Practolol treatment in asthmatics. PMID- 4143624 TI - Inhibition of transformation of normal lymphocytes by plasma factor from patients with Hodgkin's disease and cancer. PMID- 4143625 TI - Probenecid test in Parkinson's disease. PMID- 4143626 TI - Corpus alienum nasi nocte inhalation. PMID- 4143627 TI - Hepatitis-associated antigen in human bile. PMID- 4143628 TI - An epiphysometer and the community diagnosis of nutritional rickets. PMID- 4143629 TI - Use of split-screen video tapes for ultrasound training. PMID- 4143630 TI - Smoking, coughing, laughing and applause: a comparative study of respiratory symbolism. PMID- 4143631 TI - Bibliography of developmental medicine and child neurology. Selected books and articles received in 1973. PMID- 4143632 TI - Osmium tetroxide-zinc iodide reactive sites in the photoreceptor cells. PMID- 4143633 TI - A dynamic presentation of physiological phenomena. PMID- 4143634 TI - [Peri-ampullary tumors]. PMID- 4143635 TI - Biomedical communications: the state of the art. PMID- 4143636 TI - The value of immunofluorescence in the diagnosis of glomerulonephritis not related to systemic diseases. PMID- 4143637 TI - Fine structural cytochemistry of granules in atrial cardiocytes. PMID- 4143638 TI - Treatment of stage-II carcinoma of the female breast. PMID- 4143639 TI - [New amino acid derivatives with oncolytic action]. AB - A total of 27 new derivatives have been obtained by substitution on seven amino acids and betaines, respectively. The present experimental study examines the oncolytic and oncostatic action of four new amino acid compounds. Under experimental conditions in vitro the following remarkable properties of the chemical preparations can be ascertained on Ehrlich's tumor cells of the white mouse: 1. The oncolysis detected by micromorphology only occurs after an incubation of 4-6 hours, the transplantability of the tumor cells is lost much earlier. 2. The anaerobic glycolysis is in no case limited, the cell respiration is stimulated under the influence of amino acid compounds. 3. The Crabtree effect on Ehrlich ascites tumor cells is inhibited by the test substances. The irreversible damage caused by the new amino acid compounds to the Ehrlich tumor cells and observed in vitro only occurs with large excess of the substances. The mechanism of action may be due to a substrate-like excess inhibition, a disturbance of the amino acid sequence within the cell proteins being discussed. Therapeutic inhibition tests on experimental animal tumors have shown that an effect may only be expected after the application of high doses and prolonged administration. The extremely low general toxicity and the lack of any disturbance of the hematopoietic system permit a long-time application of the amino acid compounds. PMID- 4143640 TI - [Classification of leukemias]. AB - The principles according to modern views and practical needs of classification of acute leukemia are discussed on the basis of morphological properties of the leukemic cells after panoptic staining and of their cytochemical reactions. This form of classification gives some indications for the choice of treatment and for the prognosis. It is also the permission for the evaluation of therapeutic results, as are the other factors relevant for the prognosis. PMID- 4143641 TI - Anomalous volume change of gramicidin A in ethanol solutions. PMID- 4143642 TI - Glutamate dehydrogenase from human liver. III. Antibody-binding sites and properties of the antigen-antibody complex. PMID- 4143643 TI - The molecular basis for the storage and release of histamine in rat mast cell granules. PMID- 4143644 TI - Steroid protein interactions. XXVIII. The isoelectric point and pH stability of the progesterone-binding globulin. PMID- 4143646 TI - Agents which inhibit reverse transcriptases. PMID- 4143647 TI - A rapid method for studying vascular patterns three dimensionally and histologically. PMID- 4143648 TI - Urinary excretion of free norepinephrine and free epinephrine in patients with acute myocardial infarction in relation to its clinical course. PMID- 4143649 TI - Genetic polymorphism of gamma-globulins in man. PMID- 4143650 TI - Immunoglobulin abnormalities in families of patients with Waldenstrom's macroglobulinemia. PMID- 4143651 TI - The palliative treatment of recurrent carcinoma of rectum and rectosigmoid with 2 mv. radiation. Some results and description of a technique. PMID- 4143652 TI - Palliative irradiation for bladder carcinoma. PMID- 4143653 TI - Introduction to the histochemical study of carbohydrate metabolism in the lymph vascular wall. PMID- 4143654 TI - Epiphyseal growth: speculations on the nature of Perthes's disease. PMID- 4143655 TI - Analyses of obstructed micturition. PMID- 4143656 TI - Motor vehicle exhaust at three selected sites. PMID- 4143657 TI - Carbon monoxide control in a high highway tunnel. PMID- 4143658 TI - Irradiated automobile exhaust. Its effects on the reproduction of mice. PMID- 4143659 TI - Acute toxicity of irradiated auto exhaust. Its indication by enhancement of mortality from streptococcal pneumonia. PMID- 4143660 TI - Lindane and hematologic reactions. PMID- 4143661 TI - Experience with the Souttar tube in esophageal carcinoma. PMID- 4143662 TI - Developmental evaluation and therapy program. Functional approach to developmental delays in infant behavior. PMID- 4143663 TI - Smoking--a world problem. PMID- 4143664 TI - The effect of 5-fluorouracil on adrenocortical and pituitary function. PMID- 4143665 TI - Light-microscopic and immunopathologic observations on cadmium chloride-induced injury in mature rat testis. PMID- 4143666 TI - A light- and electron-microscopic study of bacterial invasion in Whipple's disease. PMID- 4143667 TI - A palliative procedure for high bile duct carcinoma. PMID- 4143668 TI - Degos' acanthoma (acanthome a cellules claires). A clinical and histological report of nine cases. PMID- 4143669 TI - A new experimental method for evaluating drugs in the nasal cavity. PMID- 4143670 TI - Spontaneous electrical activity of human muscle. PMID- 4143672 TI - Electroencephalographic studies in "split brain" cats. PMID- 4143671 TI - Pathways of descending influence on H reflex during sleep. PMID- 4143673 TI - Effect of brain lesions on conditioned cortical electropotentials. PMID- 4143674 TI - [Modification of the cerebral electrical activity of the rabbit by micro injections of monoamine precursors into bulbar and pontine sleep-producing structures]. PMID- 4143676 TI - Depth electrographic studies on the caudate nucleus in man. PMID- 4143675 TI - The evoked cortical somatosensory response in normal man and its modification by oral lithium carbonate. PMID- 4143677 TI - Hypnotic suggestions and visually evoked potentials. PMID- 4143678 TI - Unilateral suppression of vertex sharp waves in the sleep electroencephalogram (case report). PMID- 4143679 TI - Fabrication of suction-cup electrodes for electromyography. PMID- 4143680 TI - A method for analyzing variations in evoked responses. PMID- 4143681 TI - An implanted electrode for recording both rapid eye movements and muscle tone during sleep. PMID- 4143682 TI - Summated human EEG potentials with voluntary movement. PMID- 4143683 TI - [EEG and behavioral effects of deprivation of paradoxical sleep in cats]. PMID- 4143684 TI - Diffuse regulation of visual thalamo-cortical responsiveness during sleep and wakefulness. PMID- 4143685 TI - Interaction of evoked potentials in the anterior thalamus of the cat. PMID- 4143687 TI - Acoustic habituation in cats as a function of stimulus rate and the role of temporal conditioning of the middle ear muscles. PMID- 4143686 TI - [Influence of the visual cortex on the activity evoked in the subcortical optic pathways]. PMID- 4143688 TI - Electrocorticogram during whole body vibration. PMID- 4143689 TI - An EEG-behavioral study of sodium hydroxybutyrate in humans. PMID- 4143690 TI - Observations on the passive electrical properties of the envelopes of cat brain. PMID- 4143691 TI - Electrical transmission properties of the cranium of the dog to steady currents. PMID- 4143692 TI - Changes in total amount of stage four sleep as a function of partial sleep deprivation. PMID- 4143693 TI - Restoring rectangular pulses of stimulation current. PMID- 4143694 TI - Studies on biologic properties of tuberculin-active peptide. Antigenicity of tuberculin-active peptide in indirect hemagglutination and hemolytic reaction. PMID- 4143695 TI - A concept of otolaryngologic allergy. PMID- 4143696 TI - Effects of thiouracil on rat liver alpha-glycerophosphate dehydrogenase and serum PBI responses to L-thyroxine. PMID- 4143697 TI - Effects of phenethyl alcohol on chromosomes of Allium cepa. PMID- 4143698 TI - The role of cytoplasmic membranes in the regulation of water concentration within frog oocytes. PMID- 4143699 TI - Configuration of endocardial and intramural extrasystoles in the dog. PMID- 4143700 TI - Relation of vulnerability to ECG and action potential characteristics of premature beats. PMID- 4143701 TI - Microspectrophotometry of trypsin-Leishman-stained human chromosomes. PMID- 4143703 TI - Genesis and evolution of ectopic ventricular rhythm. PMID- 4143704 TI - Hypertension, diabetes mellitus, and blood groups in benign prostatic hypertrophy. PMID- 4143705 TI - Injection treatment of enlarged prostate. PMID- 4143706 TI - The arthritis of familial Mediterranean fever (FMF). PMID- 4143707 TI - An immunofluorescent study of the skin lesions in systemic lupus erythematosus. PMID- 4143709 TI - Study of cutaneous innervation in congenital anesthesia. PMID- 4143710 TI - Fetal maturation and amniotic fluid. PMID- 4143711 TI - Pterygium and pinguecula: electron microscopic study. PMID- 4143712 TI - The influence of splitting off sialic acid on activity of human erythrocytes toward H and HI antibodies. PMID- 4143713 TI - Differences of H specificity of human group O erythrocytes. PMID- 4143714 TI - A and B blood group specificities of stroma fractions of cord blood erythrocytes. PMID- 4143715 TI - Occurrence of gamma-globulin-like antigens in bacteria. PMID- 4143716 TI - Occurrence of anti-gamma-globulin antibodies in human sera. PMID- 4143717 TI - Paroxysmal ventricular tachycardia with rate-dependent coupling intervals. PMID- 4143718 TI - Release of thyroxine from the liver during anaesthesia and surgery. PMID- 4143719 TI - Anaesthesia for cardioversion: thiopentone with and without atropine premedication. PMID- 4143720 TI - Banding of the pulmonary artery for transposition of the great arteries and ventricular septal defect. PMID- 4143721 TI - Acute respiratory distress in adults. PMID- 4143722 TI - Evaluation of an antidiuretic effect in cancer. PMID- 4143723 TI - The cri-du-chat syndrome with an apparently normal karyotype. PMID- 4143724 TI - Specific inhibition of the Prausnitz-Kustner reaction by an atypical human myeloma protein. PMID- 4143725 TI - Intravascular Salmonella typhi as a manifestation of the carrier state. PMID- 4143726 TI - Effects of anti-inflammatory drugs on lymphocytes. PMID- 4143727 TI - Withdrawal fits in barbiturate addicts. PMID- 4143728 TI - Ketone bodies and the inhibition of free-fatty-acid release. PMID- 4143729 TI - Intraduodenal glucose infusion and pancreatic secretion in man. PMID- 4143730 TI - Modern concepts of free-fatty-acid and blood-glucose homoeostasis in diseases involving altered lipid metabolism. PMID- 4143731 TI - A new oxygen tent. PMID- 4143732 TI - A self-inflating cuffed neonate tracheostomy tube suitable for intermittent positive-pressure respiration. PMID- 4143733 TI - The persistent Salmonella. PMID- 4143734 TI - "Allergic gastroenteropathy". PMID- 4143735 TI - Brucellosis in the dairy-farming community and allied workers of Worcestershire. PMID- 4143736 TI - Supervision of clinical investigations. Report by Royal College of Physicians. PMID- 4143737 TI - Three doctors and the American Revolution. PMID- 4143738 TI - Chloramphenicol and jaundice in a baby. PMID- 4143739 TI - Neurotoxic side-effects of piperazine. PMID- 4143740 TI - Amitriptyline and sputum viscosity. PMID- 4143741 TI - The management of malignant tumors of the nasal sinuses. PMID- 4143742 TI - The medical treatment of sinusitis. PMID- 4143743 TI - Mechanism of immunologic unresponsiveness: a new approach. PMID- 4143744 TI - Antiplasmins. PMID- 4143745 TI - The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. PMID- 4143746 TI - Histochemical duality of rabbit intrafusal fibers. PMID- 4143747 TI - [Study of the pigment found in the peripheral giant cell granuloma]. PMID- 4143748 TI - Influence of various catatoxic steroids upon chronic dihydrotachysterol intoxication. PMID- 4143749 TI - [Studies of corneal metabolism by radioactive isotope. Report II. The effect of therapeutic substances in 35S-sulfate incorporation on the rabbit cornea]. PMID- 4143750 TI - [Effects of retinal detachment surgery on healing of corneal wound. Report I. Effects of scleral resection on healing of experimentally induced corneal wound of rabbit]. PMID- 4143751 TI - [Effects of retinal detachment surgery on healing of corneal wound. Report II. Effects of scleral penetrating diathermy on healing of experimentally induced corneal wound of rabbit]. PMID- 4143752 TI - [Effects of retinal detachment surgery on healing of corneal wound. Report III. Comparison of effects of scleral resection and scleral penetrating diathermy on healing of corneal wounds]. PMID- 4143753 TI - Alopecia from oral contraceptives. PMID- 4143754 TI - Photoperiods and age as factors modifying the effects of kepone in Japanese quail. PMID- 4143755 TI - Antinuclear factors in rheumatoid arthritis. Increasing organ-non-specificity with increasing reactivity of rheumatoid factor with heterologous gamma globulin. PMID- 4143756 TI - A study of serum proteinogram and its correlation with severity and duration in tubercular meningitis. PMID- 4143757 TI - Specific stroma in the cortex and medulla of the ovary. Cell types and vascular supply in relation to follicular apparatus and ovulation. PMID- 4143758 TI - Achilles reflex speed during pregnancy. PMID- 4143759 TI - Synergistic effect of combinations of sulfamethoxazole, trimethoprim, and colistin against Pseudomonas maltophilia and Pseudomonas cepacia. AB - Eighteen strains of Pseudomonas maltophilia and eight strains of P. cepacia were tested for susceptibility to sulfamethoxazole, trimethoprim, and colistin in different combinations. A synergistic effect was found against most of the strains. PMID- 4143760 TI - [Air pollution]. PMID- 4143761 TI - Refsum's disease. A clinical and pathological report. PMID- 4143762 TI - [The permeability of the larval integument of 1st-stage Hypoderma bovis De Geer for radioactive isotope-labelled amino acids]. PMID- 4143763 TI - [The flight dispersion distance of Oestrus ovis L. botflies]. PMID- 4143764 TI - [The proteolytic activity of some cestode species]. PMID- 4143765 TI - [The physiology of motor activity in cestodes]. PMID- 4143766 TI - [The virulence of the dysentery amoeba for laboratory rats irradiated with different doses of x-rays]. PMID- 4143767 TI - [The finding of an Ixodes eldaricus Djap., 1950 (Ixodoidea, Ixodidae) tick on rodents in the Kopet-Dag]. PMID- 4143768 TI - [The virulence of Eimeria sp. isolated from Mus musculus]. PMID- 4143769 TI - [Bloodsucking Diptera from the central regions of Magadan Province]. PMID- 4143770 TI - [Possibilities of body's adaptation to work shifts and night work]. PMID- 4143771 TI - [Clinical syndromes caused by different diapasons of radio frequency]. PMID- 4143772 TI - [Diseases of arms and the spine in textile workers]. PMID- 4143773 TI - [Qualitative changes of the sebum-secreting function of the sebaceous glands under the action of acetone, benzene and white spirit in industrial workers]. PMID- 4143774 TI - [Standardization of maximum permissible concentration of industrial dust]. PMID- 4143775 TI - [Treatment of occupational dermatitis and eczema with external application of corticosteroids]. PMID- 4143776 TI - [Inhibition of benzol oxidation by several antioxidants]. PMID- 4143777 TI - [Toxicity of isoprene and the maximum permissible concentration of its vapors in the air of workplace]. PMID- 4143778 TI - [Effects of coal dust on the epithelium of the airways (an experimental study)]. PMID- 4143779 TI - [Mechanisms of action of ethylenediamine-bis-isopropyl phosphinic acid disodium salt (phosphicin)]. PMID- 4143780 TI - [Prepatellar bursitis developing on the background of chronic trauma]. PMID- 4143781 TI - [A case of articular osteochondromatosis]. PMID- 4143782 TI - [Clinical aspects of vibration disease in drillers and tunnelers]. PMID- 4143783 TI - [Determination of carbofos and intermediate products of its synthesis in the air]. PMID- 4143785 TI - [All-Union scientific-practical conference in Donetsk concerning problems of industrial hygiene in the coal industry (III 1964)]. PMID- 4143784 TI - [Colorimetric method of determining beryllium with beryllon II in the air]. PMID- 4143786 TI - [Scientific-practical conference in Kiev concerning problems of industrial hygiene in chemical industry (IV 1964)]. PMID- 4143787 TI - [Industrial hygiene and occupational diseases in high-voltage testing of electric equipment]. PMID- 4143789 TI - [1st International Seminar on Dental Materials. Caracas, Venezuela, 12-15 March 1973]. PMID- 4143788 TI - [Salivary acid-base equilibrium and dental caries]. PMID- 4143790 TI - [Relationship between laboratory investigations and clinical studies]. PMID- 4143791 TI - [Statistical method in scientific investigation. Its use in the investigation of dental materials]. PMID- 4143792 TI - [Present state of teaching and study of dental materials in Central America and Panama and proposal of a means for their substantial improvement]. PMID- 4143793 TI - [Origin, implementation and expansion of the program for standardization of dental materials in Australia]. PMID- 4143794 TI - [Educational principles to be considered at the preprofessional level]. PMID- 4143795 TI - [Content of a course on dental materials]. PMID- 4143796 TI - [Postgraduate courses for professors of dental materials and related clinical activities]. PMID- 4143797 TI - [Materials and new methods for restorative dentistry]. PMID- 4143798 TI - [Development of dental materials with improved properties]. PMID- 4143799 TI - [The development of a new program of standards for dental materials in Canada]. PMID- 4143800 TI - [Preliminary report on four experimental projects]. PMID- 4143801 TI - [Testing and control of therapeutic materials and drugs]. PMID- 4143802 TI - [Philosophy and antecedents of national and international standardization and quality control of dental materials]. PMID- 4143803 TI - [The need for national programs for dental materials]. PMID- 4143804 TI - [Philosophy and objectives of the program of the National Center for Dental Materials]. PMID- 4143805 TI - [Problems with standardization and quality control in Argentina with respect to teaching and testing]. PMID- 4143806 TI - [Dental materials and standardization]. PMID- 4143807 TI - [Standardization of dental materials in Colombia]. PMID- 4143808 TI - [Development of South American tests and specifications. The Brazilian experience]. PMID- 4143812 TI - The young child's development of sentence comprehension: influence of event probability, nonverbal context, syntactic form, and strategies. PMID- 4143813 TI - Variations in children's concepts by age and category. PMID- 4143814 TI - The effects of adult models and described alternatives on children's choice of behavior management techniques. PMID- 4143815 TI - Prior help, ego development, and helping behavior. PMID- 4143816 TI - Children's recognition of reversals of geometric figures. PMID- 4143817 TI - Letter reversals in naming, writing, and matching to sample. PMID- 4143818 TI - The ability of six-year-olds, eight-year-olds, and adults to abstract visual patterns. PMID- 4143819 TI - Cognitive integration in children's memory for sentences and pictures. PMID- 4143820 TI - The effect of verbal cues on concept acquisition and retention in normal and educable mentally retarded children. PMID- 4143821 TI - Recognition memory in Down's syndrome and normal infants. PMID- 4143822 TI - Pleasure derived by children from cognitive challenge and mastery. PMID- 4143823 TI - Development of peer interactions of monkeys reared in a nuclear-family environment. PMID- 4143824 TI - Anxious attachment and defensive reactions associated with day care. PMID- 4143825 TI - The use of perceptual cues for number judgment by young children. PMID- 4143826 TI - How preschool children understand missing complement subjects. PMID- 4143827 TI - Cognitive maps in children and men. PMID- 4143828 TI - The role of number and length cues in children's quantitative judgments. PMID- 4143829 TI - Relationships among Piagetian, IQ, and achievement assessments. PMID- 4143830 TI - Attention and manipulative play in the one-year-old child. PMID- 4143831 TI - Reflectivity, internality, and animistic thinking. PMID- 4143832 TI - Observational learning of motives and consequences for television aggression: a developmental study. PMID- 4143833 TI - A structural-developmental analysis of levels of role taking in middle childhood. PMID- 4143834 TI - Birth order, verbal intelligence, and educational aspiration. PMID- 4143835 TI - Value and chroma discriminations of young children and adults. PMID- 4143836 TI - Acquisition and transfer of sorting mechanisms in discrimination learning and free recall by nursery school children. PMID- 4143837 TI - Comparison of the retention of preschool and second-grade performers and observers under three verbalization conditions. PMID- 4143838 TI - The development of time concepts through conflict based on a primitive duration capacity. PMID- 4143839 TI - Social and familial correlates of self-esteem among American Indian children. PMID- 4143840 TI - Socioeconomic status differences in children's discrimination learning as related to the reward and information functions of response-contingent stimuli. PMID- 4143841 TI - Conservation of different quantities among preschool children. PMID- 4143842 TI - Negative teacher expectation and IQ change in children with superior intellectual potential. PMID- 4143843 TI - An analysis of analogical reasoning in children. PMID- 4143844 TI - The effect of need for approval and incentives upon children's probability learning responses. PMID- 4143845 TI - Social stimulation of vocalizations in delayed infants: familiar and novel agent. PMID- 4143846 TI - Generalized habituation of concept stimuli in toddlers. PMID- 4143847 TI - Birth order, family configuration, and verbal achievement. PMID- 4143848 TI - Judgment and imaging aspects of operations: a Piagetian study with Korean and Costa Rican children. PMID- 4143849 TI - Modification of young children's grouping strategies: the effects of modeling, verbalization, incentives, and age. PMID- 4143850 TI - Development of pictorial depth perception: cross-cultural replications. PMID- 4143851 TI - The comparative ease of processing standard English and black nonstandard English by lower-class black children. PMID- 4143852 TI - The development of the category-recall function under three retrieval conditions. PMID- 4143853 TI - Personal organization in children's free recall. PMID- 4143854 TI - Recognition, formulation, and integration in the development of interrogative strategies among normal and retarded children. PMID- 4143855 TI - Primacy effects in short-term memory with the mentally retarded. PMID- 4143857 TI - Imposed inhibition and delay of gratification. PMID- 4143856 TI - Instrumental ideation in delay of gratification. PMID- 4143858 TI - Does imagery retard conceptual behavior? PMID- 4143859 TI - Joking and appreciation of humor in nursery school children. PMID- 4143860 TI - The effects of being imitated on children's responses in a marble-dropping task. PMID- 4143861 TI - Altering the questioning strategies of preschool children. PMID- 4143862 TI - The perception of eye contact in children and adults. PMID- 4143863 TI - Early peer-group interaction and role-taking skills: an investigation of Israeli children. PMID- 4143864 TI - Class-inclusion failure: cognitive deficit or misleading reference? PMID- 4143865 TI - Observed maternal behavior with four-year-old boys and girls in lower-class families. PMID- 4143866 TI - Television as baby-sitter: a field comparison of preschoolers' behavior during playtime and during television viewing. PMID- 4143867 TI - Self-concept as related to achievement and age in learning-disabled children. PMID- 4143868 TI - Effects of extrinsic rewards on children's subsequent intrinsic interest. PMID- 4143869 TI - Discrimination learning in normal and retarded children as a function of instructions, cue locus, and cue relevance. PMID- 4143870 TI - Discrimination of schematic faces by nursery school children. PMID- 4143871 TI - Developmental differences in infants' attentional responses to face-voice incongruity of mother and stranger. PMID- 4143872 TI - Effects of age, sex, and partner on children's dyadic speech. PMID- 4143873 TI - A developmental study of strategies of visual selectivity. PMID- 4143874 TI - The effects of preference for visual complexity on habituation of visual fixation in infants. PMID- 4143875 TI - Effect of spatial separation of stimuli on children's discrimination learning. PMID- 4143876 TI - The influence of dimensional manipulations on class-inclusion performance. PMID- 4143877 TI - Cohort, age, and imagery in children's paired-associate learning. PMID- 4143878 TI - The postnatal growth of visual capacity. PMID- 4143879 TI - On the psychological reality of cognitive structures: a tentative synthesis of Piaget's and Bruner's theories. PMID- 4143880 TI - A basis for identifying stimuli which control behaviors in natural settings. PMID- 4143881 TI - The effects of sociodramatic play on problem-solving behavior among culturally disadvantaged preschool children. PMID- 4143882 TI - Information-generated influence as a function of locus-of-control patterns in children. PMID- 4143883 TI - Obstetrical pain-relieving drugs as predictors of infant behavior variability. PMID- 4143884 TI - A system for monitoring crying and noncrying, large, medium, and small neonatal movements. PMID- 4143886 TI - Visual preferences of four-month-old premature and full-term infants. PMID- 4143885 TI - Characteristics of crying and noncrying activity of full-term neonates. PMID- 4143887 TI - A neurological and behavioral comparison of African and European newborns in Uganda. PMID- 4143888 TI - Planfulness and recognition memory. PMID- 4143889 TI - The development of a preference for logical consistency in school mathematics. PMID- 4143890 TI - Investigations of the meaning of "different" in the language of young children. PMID- 4143891 TI - Transmission of hepatitis. PMID- 4143892 TI - [Audiovisual aids in the Faculty of Odontology of the University of the Andes]. PMID- 4143893 TI - The use of symbolic modeling to promote social skills in preschool children with low levels of social responsiveness. PMID- 4143894 TI - Fluoridation in Canberra. II. Dental caries after six years. PMID- 4143895 TI - Closing volume in healthy non-smokers. PMID- 4143896 TI - Oral orciprenaline, salbutamol and isoetharine compared. PMID- 4143897 TI - Partial purification and some properties of the uridine diphospho-N acetylglucosamine-enolpyruvate reductase from Staphylococcus epidermidis. AB - A method for the partial purification of the uridine diphospho-N acetylglucosamine-enolpyruvate reductase from Staphylococcus epidermidis is presented. Some properties of the enzyme, including its dependence on monovalent cation and flavine adenine dinucleotide, are discussed. PMID- 4143898 TI - Lipogenic enzyme activity in adipose tissue during the growth of swine with different propensities to fatten. PMID- 4143899 TI - A comparison of husband-wife responses to pregnancy. PMID- 4143900 TI - Effect of vitamin D3 on the transformation of 7-dehydrocholesterol to cholesterol in the rat liver. PMID- 4143901 TI - Physician's assistants--nurse associates. An overview. PMID- 4143902 TI - Role of catecholamines in the control of melanocyte-stimulating hormone secretion in rats. PMID- 4143903 TI - [Beta blockaders and facial vascular pain (apropos of 4 cases)]. PMID- 4143905 TI - [R. Geigy. List of publications]. PMID- 4143904 TI - [Systemic diseases and liver involvement: a review]. PMID- 4143906 TI - [Apropos of cholera and anticholera vaccination as discussed at the symposium organized by WHO in Bamako (Mali) in March 1972]. PMID- 4143907 TI - Cellular response to drugs affecting aqueous dynamics. PMID- 4143908 TI - [Comparative study of chronotropic and inotropic effects of different beta adrenolytic drugs]. PMID- 4143909 TI - [7,12 Dimethylbenz(a)anthracene metabolism by the intestinal flora of mice in vitro]. PMID- 4143910 TI - [Functioning of reinforcement systems and interspecific aggression behavior in rats: effect of thiproperazine]. PMID- 4143911 TI - [Detoxification by liver microsomes]. PMID- 4143912 TI - [Effect of pyrazoline and hydrazine derivatives on the resistance of mice to hypoxia]. PMID- 4143913 TI - Industrial injuries of the back and extremities. Comprehensive evaluation--an aid in prognosis and management: a study of one hundred and eighty patients. PMID- 4143915 TI - Biosynthesis of progesterone from endogenous steroid precursor by the guinea-pig placenta. PMID- 4143914 TI - Enzyme assays in liver disease. PMID- 4143916 TI - Head injury. PMID- 4143917 TI - [Hematopoietic stem cells, the thymus dependent lymphatic system and primary immune deficiencies of childhood]. PMID- 4143918 TI - Human blood platelets as cellular models for investigation of membrane active drugs: beta-adrenergic blocking agents. PMID- 4143919 TI - The American Academy of Forensic Sciences: organizing a new intellectual discipline. PMID- 4143920 TI - [Autolysis of bacterial cell surface and its physiology (biosynthesis)]. PMID- 4143921 TI - [Arachnidism caused by Phoneutria in Costa Rica (Araneae: Ctenidae)]. PMID- 4143922 TI - Tektite II; medical supervision of the scientists in the sea. X. The aborted 100 FSW (Minitat) program. PMID- 4143923 TI - Tektite II: medical supervision of the scientists in the sea. 9. Tektite logistics. PMID- 4143924 TI - (Glutamine synthetase) tyrosyl-O-adenylate: a new energy-rich phosphate bond. PMID- 4143925 TI - Enzyme adaptation as a biochemical probe of development and aging. PMID- 4143926 TI - Mosquito host preference studies in Hale County, Texas. PMID- 4143927 TI - The footballer's ankle and foot. PMID- 4143928 TI - [Present problems of dentistry at a course of World Health Organization in Moscow]. PMID- 4143930 TI - Training and utilization of feldshers in the USSR. PMID- 4143929 TI - Pneumococcal transformation--a backward view. Fourth Griffith Memorial Lecture. PMID- 4143931 TI - [Care of mental health of dialyzed patients]. PMID- 4143932 TI - [Gamma-glutamyl transpeptidase (gamma-GTP): determination of gamma-GTP and its clinical significance in heart diseases]. PMID- 4143933 TI - [Gamma-GTPase and liver diseases]. PMID- 4143934 TI - [Clinical significance of gamma-glutamyl transpeptidase isoenzymes]. PMID- 4143935 TI - [Significance of gamma-GTP analysis in surgical diseases]. PMID- 4143936 TI - [Histocytochemistry of gamma-GTP in the liver]. PMID- 4143937 TI - [Gamma-GTP in cancer]. PMID- 4143938 TI - Enzyme induction in human fetal liver. PMID- 4143939 TI - Enzymatic activity hydrolyzing -glutamyl- -naphthylamide in human intestine during adult and fetal life. PMID- 4143940 TI - A standardized system for diagnosing, recording and analyzing dental caries data. PMID- 4143941 TI - [Mechanism of action of histones on the respiratory chain of mitochondria]. PMID- 4143942 TI - -Glutamyl transpeptidase: elevated activities in certain neurologic diseases. PMID- 4143943 TI - The volunteer rescue squad: the impact of a group on the psychological adaptation of its members. PMID- 4143944 TI - The effect of regressive ECT with process schizophrenics. PMID- 4143945 TI - Phenothiazine deaths: a critical review. PMID- 4143946 TI - Impairment of optokinetic nystagmus in patients with tardive dyskinesia. PMID- 4143947 TI - Identification and analysis of arachidonic acid in Plexaura homomalla, var. R and var. S. PMID- 4143948 TI - Alkane oxidation in Candida tropicalis. PMID- 4143950 TI - [Kinetic and thermodynamic study of erythrocyte glucose-6-phosphate dehydrogenase in humans. Application to 7 different variants in the negroid race]. PMID- 4143949 TI - Red cell metabolism. A. Defects not causing hemolytic disease. B. Environmental modification. PMID- 4143951 TI - A new cardioselective -adrenoceptor blocking agent. PMID- 4143952 TI - Contributions of neurochemistry to neurology and psychiatry. Introduction. PMID- 4143953 TI - Parkinson's disease: from brain homogenate to treatment. PMID- 4143954 TI - Beta adrenergic mechanisms influencing brain steady potential in cats and Rhesus monkeys. PMID- 4143955 TI - 2-Amine 4-pentenoic acid (allylglycine): a proposed tool for the study of GABA mediated systems. PMID- 4143956 TI - Activity of glutamate and malate dehydrogenases and the 'malic enzyme' during the development of the chick spinal cord. PMID- 4143957 TI - Degradation of protocatechuate in Pseudomonas testosteroni by a pathway involving oxidation of the product of meta-fission. AB - In addition to catalyzing the hydrolysis of 4-carboxy-2-hydroxymuconic semialdehyde, formed by meta-fission of protocatechuate, Pseudomonas testosteroni also possesses a nicotinamide adenine dinucleotide(phosphate)-linked dehydrogenase for this compound and can degrade protocatechuate to pyruvate and oxaloacetate. PMID- 4143958 TI - Personality processes reflected in client vocal style and Rorschach performance. PMID- 4143959 TI - Interpretation of uninterpretable Minnesota Multiphasic Personality Inventory profiles. PMID- 4143960 TI - Pyrimidine metabolism in man. PMID- 4143961 TI - The pharmacology of platelet inhibition. PMID- 4143962 TI - Immunomorphological methods in the diagnosis of lung diseases. PMID- 4143963 TI - The undescended testis. PMID- 4143964 TI - Allogeneic interactions provide evidence for a novel class of immunological reactivity. PMID- 4143965 TI - Allograft response in vitro. PMID- 4143966 TI - Heat treatment of soldered joints in dental casting gold alloys. An electron microprobe analysis. PMID- 4143967 TI - Effect of renal alpha-adrenergic stimulation on proximal tubular sodium reabsorption. PMID- 4143968 TI - Interaction of embryonic chicken spleen cells and adult allogeneic leucocytes. PMID- 4143969 TI - The in vitro response to phytohaemagglutinin (PHA) of leucocytes from intact and thymectomized quokkas. PMID- 4143970 TI - Studies on the mitochondrial energy-linked pyridine nucleotide transhydrogenase. PMID- 4143971 TI - [Mechanism of action of insulin and fasting on fatty acid synthesis in the liver and adipose tissue]. PMID- 4143972 TI - [Importance and role of imidazole and sulfhydryl groups in the catalytic activity of human erythrocyte glucose-6-phosphate dehydrogenase]. PMID- 4143973 TI - [Oxidative phosphorylation and membrane potential]. PMID- 4143974 TI - The renal circulation in haemorrhagic hypotension. In-vivo renal micro angiography in the dog. PMID- 4143975 TI - Small-vessel changes in renal disease. PMID- 4143976 TI - Modified nucleosides with antineoplastic activity as inhibitors of an enzyme containing adenosine within its coenzyme. PMID- 4143977 TI - Folate deficiency and formiminoglutamic acid excretion during chronic diethylnitrosamine administration to rats. PMID- 4143978 TI - Studies on the nature of the bronchial -adrenoreceptors. PMID- 4143981 TI - Characteristics of disparate histocompatibility barriers in congenic strains of mice. II. Antibody-associated suppression. PMID- 4143982 TI - [Tyrosine alpha-ketoglutarate transaminase activity in the chick embryo (White Leghorn) liver during embryogenesis]. PMID- 4143983 TI - The control of dental caries and periodontal disease; a fundamental approach. PMID- 4143984 TI - Interexaminer variability when using Viegas' simplified caries index. PMID- 4143985 TI - The enzymatic and immunologic detection of myocardial injury. Selected considerations. PMID- 4143986 TI - The failing myocardium. I. Drug management. PMID- 4143987 TI - Experiences with beta-adrenergic blockade drugs in hypertension. PMID- 4143988 TI - [IR, Raman, 1 H-NMR spectra and acidity constants of the cytostatic Hadacidin and its mono alkali salts]. PMID- 4143989 TI - [UV-dimerization of 1,3-dimethyluracil in ice-matrix]. PMID- 4143990 TI - [Structure determination of dimeric 1,3-dimethyl-uracils by 1 H-NMR spectroscopy]. PMID- 4143991 TI - [Kinetic and chemical study of succinyl papain]. PMID- 4143992 TI - Loss of biological activity of bacteriophage 2C and degradation of its DNA in storage. PMID- 4143993 TI - [The effect of hydroxyurea on DNA synthesis of embryonic rat cells in culture]. PMID- 4143994 TI - [Properties of a low-molecular weight DNA from embryonic rat cells in culture]. PMID- 4143995 TI - Ultraviolet absorption and optical rotatory dispersion studies of deoxyribonucleic acid and nucleohistone. PMID- 4143996 TI - Oxygen consumption by liver and kidney slices of Uromastix hardwickii. PMID- 4143997 TI - Studies on carbohydrate metabolism in lizards. PMID- 4143998 TI - The effect of some sodium substitutes on the receptor potential of the crayfish photoreceptor cell. PMID- 4143999 TI - [Cancer cell kinetics and cancer multi-step therapy]. PMID- 4144000 TI - [Electron microscopic observation of isolated mitochondria of Tetrahymena pyriformis]. PMID- 4144001 TI - [Bacteria in the macronucleus of Loxophyllum meleagris]. PMID- 4144002 TI - [Stimulation of embryonic rat cells in culture by calf-serum. IV. Isolation of an Active Protein and Partial Purification of a second Stimulating Fraction from fetal calf-serum]. PMID- 4144003 TI - Effect on caries susceptibility after surgical treatment of drooling in patients with neurological disorders. PMID- 4144004 TI - Genetic control of histocompatibility antigens. PMID- 4144005 TI - Source of pyrrole-2-carboxylate in mammalian urine. PMID- 4144006 TI - An NAD- and NADP-dependent malic enzyme with regulatory properties in rat liver and adrenal cortex mitochondrial fractions. PMID- 4144007 TI - On the binding of aflatoxin B 1 and its metabolites to hepatic microsomes. PMID- 4144008 TI - The role of Ca 2+ in control of malic enzyme activity in bovine adrenal cortex mitochondria. PMID- 4144009 TI - The role of molybdenum in formation of the NADPH-nitrate reductase by Aspergillus nidulans. PMID- 4144010 TI - [Health status of university students and medical research in the USSR]. PMID- 4144011 TI - Automated fluorometric method for screening for erythrocyte glucose-6-phosphate dehydrogenase deficiency. PMID- 4144013 TI - [Lessons from a world congress]. PMID- 4144012 TI - Psychological, demographic and orthopaedic factors associated with prediction of outcome of spinal fusion. PMID- 4144014 TI - [Solder and soldering in dental technology]. PMID- 4144015 TI - Laboratory Relations Conference. PMID- 4144016 TI - Comparison of the virion polypeptides of group B arboviruses. AB - The virion polypeptides of eight group B arboviruses were compared by polyacrylamide gel coelectrophoresis. All contained three polypeptides, V-1, V-2, and V-3. The mosquito-borne viruses had electrophoretically similar small membrane polypeptides (V-1); the tick-borne viruses had a V-1 of significantly decreased mobility. PMID- 4144017 TI - Allergic responses to biting and stinging insects. PMID- 4144018 TI - Resolution of terbutaline, a new -sympathomimetic amine. PMID- 4144019 TI - The mosquitoes of the Red Sea area, Egypt. PMID- 4144020 TI - [On the treatment of angina pectoris with beta-blocking agents (Eraldin, Visken)]. PMID- 4144021 TI - [Complications in intoxications with carbamides]. PMID- 4144022 TI - Electroencephalographic effects of bicuculline. PMID- 4144023 TI - [Cardioselective beta-adrenergic blockade used in diagnostic pre-operative management of patients]. PMID- 4144024 TI - [Arthrography of the instep in diagnosis of ligament ruptures]. PMID- 4144025 TI - [Ligament injuries of the instep]. PMID- 4144026 TI - Renal transplantation in rabbits. IX. An immunological study of the allograft reaction in rabbits pre-sensitized by donor kidney homogenate. PMID- 4144027 TI - The tyrant overcome: a review of the history of anaesthesia in Australia. PMID- 4144028 TI - [Neonatal tetanus. Treatment by oral administration of diazepam and early feeding by nasogastric catheter]. PMID- 4144029 TI - [Evolution of heteroplastic grafts of the body wall among different species of the Lumbricus genus. Effect of the biotope of sample collection]. PMID- 4144030 TI - Carrier specificity and the allogeneic effect in mice. PMID- 4144031 TI - Double-blind cross-over clinical trial of oxyfedrine in angina pectoris. PMID- 4144032 TI - [Joint session of the Belgian Society of Orthopedics and Traumatology, the Belgian Rheumatologic Society and the Belgian Society for Physical Medicine and Rehabilitation]. PMID- 4144033 TI - The mediator of cellular immunity. VI. Effect of the antimitotic drug vinblastine on the mediator of cellular resistance to infection. AB - The antimitotic drug vinblastine (Vbl) has a profound impact upon the specifically sensitized lymphocytes that transfer cellular resistance to Listeria monocytogenes. A 12-h pulse of the drug given to prospective donors during the first week of an immunizing Listeria infection inhibits the delivery of protective lymphocytes to the thoracic duct and their subsequent movement into an inflammatory exudate induced in the peritoneal cavity. The effect of Vbl is clearly related to its antimitotic activity, not to an effect on lymphocytes regardless of their position in the division cycle. This conclusion was drawn from an autoradiographic analysis of cells in the lymph of Vbl-treated rats and from failure of the drug to abrogate a known function of small lymphocytes, namely, their ability to initiate a graft-vs.-host reaction. The results imply that large lymphocytes, the rapidly proliferating cells in central lymph, are the principal effector cells responsible for transmitting resistance to L. monocytogenes and provide a plausible explanation for their rapid turnover and short circulating life-span. PMID- 4144034 TI - [Otolaryngologic pathological manifestations due to side effects of drugs]. PMID- 4144035 TI - [Clinical nurses]. PMID- 4144036 TI - Lactate dehydrogenases: structure and function. PMID- 4144038 TI - Mercury vapour intoxication. PMID- 4144037 TI - Nutritional evaluation of humans during an oxygen-helium dive to a simulated depth of 1000 feet. PMID- 4144039 TI - A comparative cytochemical study of the midgut epithelial cells of local vector mosquitoes unfed and fed in relation to blood meal. PMID- 4144040 TI - Preparation of hyperthyroidism using a beta-adrenergic blocker "Trasicor". PMID- 4144042 TI - [4th national sexological conference]. PMID- 4144041 TI - The physician and workmen's compensation. A new paramedic to help with compensation cases. AB - The first social, no-fault, insurance legislation in California was the Workmen's Compensation Act of 1911. It has been changed and modified in the years since, and is having an increasing impact on the practice of most California physicians. Many physicians consider caring for the occupationally ill or injured time consuming and difficult. A newly emerging kind of paramedic, the workmen's compensation benefit administrator, is available to assist the physician in overcoming difficulties encountered. A cooperative effort between the physician and the benefit administrator will expedite management of industrial patients. PMID- 4144043 TI - The rise and fall of pneumonia-control programs. PMID- 4144044 TI - The choice of alternative antidepressants. PMID- 4144045 TI - Cryptorchidism reassessed. Is there an optimal time for surgical correction? PMID- 4144046 TI - Replantation of avulsed anterior teeth in patients with jaw fractures. PMID- 4144047 TI - [Epidemiological study of Japanese encephalitis in Hokkaido. 4. Serological and climatological investigations of Japanese encephalitis virus infection in domestic animals]. PMID- 4144048 TI - The neurohumoral control of pancreatic exocrine secretion. PMID- 4144049 TI - The Rhesus monkey as a model for the study of infectious disease. PMID- 4144050 TI - Drugs in management of minimal brain dysfunction. PMID- 4144051 TI - Minimal brain dysfunction. V. Diagnosis and treatment. B. Drug treatment. Drug therapy: initiation and follow-up. PMID- 4144052 TI - Reduced triphosphopyridine-liked aldehyde reductase. II. Species and tissue distribution. PMID- 4144053 TI - Turnover of dihydrofolate reductase in rapidly dividing cells. PMID- 4144054 TI - Activation of rabbit kidney fructose diphosphatase by Mg-EDTA, Mn-EDTA and Co EDTA complexes. PMID- 4144055 TI - The effect of NADP on the subunit structure and activity of spinach chloroplast glyceraldehyde-3-phosphate dehydrogenase. PMID- 4144056 TI - ACTH stimulation of purine nucleotide biosynthesis in the adrenal cortex. ACTH stimulation of purine biosynthesis. PMID- 4144057 TI - Two isoenzymes each of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in spinach leaves. PMID- 4144059 TI - Sickle cell crisis associated with drugs. PMID- 4144058 TI - Studies of cytochrome P-450 in testis microsomes. PMID- 4144060 TI - Circular dichroism studies of dihydrofolate reductase from a methotrexate resistant strain of Escherichia coli. PMID- 4144061 TI - Isocitrate dehydrogenase from Azotobacter vinelandii. Order of substrate addition and product release. PMID- 4144062 TI - The cardiovascular actions of WR-149,024 (1,18-diamino-7,13-diaza-9,10 dithiaoctadecane tetrahydrochloride). AB - 1. The general cardiovascular properties of WR-149,024 (a straight chain sulphur containing aliphatic amine) in dogs and cats are reported.2. Intravenous administration of this compound produced an immediate hypotension and bradycardia in intact anaesthetized dogs. These effects were independent of the parasympathetic nervous system since they were also present in atropinized and bilaterally vagotomized dogs.3. Ascending aortic blood flow increased after administration of WR-149,024 despite a reduction in blood pressure, contractile force and heart rate. It appears that the initial hypotension is due to a decrease in total peripheral vascular resistance since WR-149,024 produced relatively little change in force of contraction or heart rate in the isolated, blood-perfused heart preparation.4. WR-149,024 reversed the pressor effects of adrenaline within 10 min of injection while at the same time the vasopressor response to angiotensin or the vasodepressor response to isoprenaline was not altered. alpha-Adrenoceptor blockade was still evident up to five days after dosing.5. WR-149,024 did not block phenylephrine inhibition of intestinal motility. These findings suggest that WR-149,024 initiates a relatively specific and prolonged alpha-adrenoceptor blockade. PMID- 4144063 TI - Effects of brocresine (NSD-1055) and cycloheximide on amino acid decarboxylase activities in gastric mucosa of normal and vagally denervated rats. AB - 1. Histidine decarboxylase activity of rat stomach fluctuates depending upon the functional state of the stomach. This varying enzyme activity poses special problems in assessing the effectiveness of enzyme inhibitors. After vagal denervation gastric histidine decarboxylase is markedly activated and remains at a high, stable level, which is unaffected by the functional state of the stomach. Thus it appears that vagally denervated rats are well suited for studies on histidine decarboxylase inhibitors.2. In vivo, brocresine (NSD-1055) was found to be a more effective inhibitor of gastric DOPA decarboxylase than of gastric histidine decarboxylase. With the fairly high dose given (200 mg/kg) the inhibition of histidine decarboxylase was at most 75-85% and quite short-lasting. The DOPA decarboxylase activity, which was not affected by vagal denervation, was inhibited more than 95% by brocresine; this inhibition was longer-lasting.3. Cycloheximide, which probably lowers gastric histidine decarboxylase activity by inhibiting enzyme synthesis, was maximally effective at a dose level as low as 1 mg/kg. Gastric DOPA decarboxylase was not inhibited by cycloheximide. Vagotomized rats and control rats responded similarly.4. Combined treatment of vagally denervated rats with brocresine and cycloheximide resulted in a rapid and persistent reduction of the histidine decarboxylase activity. It is concluded that the failure of brocresine alone to induce a lasting inhibition of histidine decarboxylase is due to continuous, rapid synthesis of new enzyme.5. The calculated half-life of gastric histidine decarboxylase was 75 min in vagally denervated rats and 45 min in normal fasted rats. The results suggest that the increased enzyme activity after vagal denervation is caused by an increased rate of enzyme synthesis. PMID- 4144064 TI - Antihypertensive therapy with adrenergic beta-receptor blockers and vasodilators. PMID- 4144065 TI - [The effect of 1-(isopropylamino)-3-(m-toyloxy)-2-propanol hydrochloride (Doberol) on the bronchial system after oral administration]. PMID- 4144066 TI - Studies on the prostaglandin A 2 synthetase complex from Plexaura homomalla. PMID- 4144067 TI - The histology of autologous skin grafts in the human oral cavity. PMID- 4144068 TI - Holographic investigation of the elastic deformation of defective gold solder joints. PMID- 4144069 TI - Aminopyrine demethylase activity in normal and vitamin E-deficient male rats. PMID- 4144070 TI - Ribitol and flavinogenesis in Eremothecium ashbyii. AB - 1. Supplementation of cultures of Eremothecium ashbyii with ribitol leads to a twofold increase in riboflavin formation compared with unsupplemented cultures or those supplemented with ribose or ribulose phosphate. Addition of unlabelled ribitol decreases the incorporation of [1-(14)C]ribose into riboflavin, indicating that free ribitol is preferred to ribose for incorporation into riboflavin. 2. The enzymes ribitol kinase, d-ribose reductase, d-ribose 5' phosphatase and GMP nucleosidase were demonstrated in the cell-free extracts. Ribitol induces the formation of ribitol kinase. The enzyme is activated in vitro by the flavinogenic purines, guanine and xanthine. d-Ribose reductase shows a specific requirement for NADPH and forms free ribitol from ribose. 3. The activities of ribitol kinase, ribose 5'-phosphatase and GMP nucleosidase reach their maximal values before riboflavin formation reaches a maximum. 4. [U (14)C]GMP is taken up intact by the culture of E. ashbyii and is incorporated into riboflavin as well as into a blue fluorescent compound. The radioactivity from this compound is incorporated into riboflavin by the cell-free extract of E. ashbyii. PMID- 4144071 TI - Inhibition studies on the aromatization of androst-4-ene-3,17-dione by human placental microsomal preparations. PMID- 4144072 TI - The isocitrate dehydrogenases of Acinetobacter lwoffi. Separation and properties of two nicotinamide-adenine dinucleotide phosphate-linked isoenzymes. AB - Two isoenzymes of NADP-linked isocitrate dehydrogenase have been identified in Acinetobacter lwoffi and have been termed isoenzyme-I and isoenzyme-II. The isoenzymes may be separated by ion-exchange chromatography on DEAE-cellulose, by gel filtration on Sephadex G-200, or by zonal ultracentrifugation in a sucrose gradient. Low concentrations of glyoxylate or pyruvate effect considerable stimulation of the activity of isoenzyme-II. The isoenzymes also differ in pH dependence of activity, kinetic parameters, stability to heat or urea and molecular size. Whereas isoenzyme-I resembles the NADP-linked isocitrate dehydrogenases from other organisms in having a molecular weight under 100000, isoenzyme-II is a much larger enzyme (molecular weight around 300000) resembling the NAD-linked isocitrate dehydrogenases of higher organisms. PMID- 4144073 TI - Effect of diet and also physiological state on some enzymes of carbohydrate metabolism in the liver of the domestic fowl. PMID- 4144074 TI - The purification and properties of cyclohexanone oxygenase from Nocardia globerula CL 1. PMID- 4144075 TI - The microbial metabolism of nitrilotriacetate. PMID- 4144076 TI - Negative co-operativity in glutamate dehydrogenase: coenzyme-binding studies. PMID- 4144077 TI - The type-specific substance from Pneumococcus type 13. AB - 1. The type-specific substance, S.13, from Pneumococcus type 13 was subjected to hydrolysis with alkali, followed by enzymic dephosphorylation, to yield a pentasaccharide. 2. The pentasaccharide, corresponding to the dephosphorylated repeating unit of S.13, was shown to be O-beta-d-galactopyranosyl-(1-->4)-O-beta- d-glucopyranosyl-(1-->3)-O-beta-d- galactofuranosyl-(1-->4)-O-2-acetamido-2-deoxy beta-d- glucopyranosyl-(1-->2)-ribitol. 3. The phosphodiester linkages in S.13 join the hydroxyl group at position 1 of ribitol and the hydroxyl group at position 4 of a galactopyranosyl residue in the next repeating unit. 4. Ester groups, presumably O-acetyl, are located on positions 2 or 3 of most glucopyranosyl residues in S.13. 5. A partial structure for S.13 is proposed. PMID- 4144078 TI - -Adrenergic blockers and early stages in liver regeneration. PMID- 4144079 TI - [Sudden reactions to the decrease of the barometric pressure in a pressure cabin]. PMID- 4144080 TI - A study of metabolic control and intracellular transport by multifunctional photon counting and two channel microfluorometry. PMID- 4144081 TI - On the regulation of tyrosine transaminase, glutamatic dehydrogenase and aspartic transaminase in Tetrahymena. PMID- 4144082 TI - [Monoamine oxidase. 16. Purification of monoamine oxidase from beef liver mitochondria and its enzymatic properties]. PMID- 4144083 TI - Evidence for a transient tetrameric form of glucose 6-phosphate dehydrogenase from human erythrocytes. PMID- 4144085 TI - Studies on regulatory functions of malic enzymes. II. Purification and molecular properties of nicotinamide adenine dinucleotide-linked malic enzyme from Eschericha coli. PMID- 4144084 TI - Purification and properties of nicotinamide mononucleotide amidohydrolase from Azotobacter vinelandii. PMID- 4144086 TI - On the reaction of D-amino acid oxidase with -chloro-D-alanine. PMID- 4144087 TI - Human dental caries experience related to age, sex, race, and certein salivary properties. PMID- 4144088 TI - Epidemiologic study of dental caries experience and between-meal eating patterns. PMID- 4144089 TI - Psychopathy, race, and delay of gratification by adolescent delinquents. PMID- 4144090 TI - Visual exploratory behavior as a function of manifest anxiety. PMID- 4144092 TI - [An epidemiological study of caries in Dental Service District patients]. PMID- 4144091 TI - [Treatment of paroxysmal disorders of cardiac rhythm]. PMID- 4144093 TI - [An epidemiological study of caries in Gloppen dental district, Sogn and Fjordane]. PMID- 4144094 TI - [Functional changes of the thyroid and adrenal glands in the course of immunological reactions]. PMID- 4144095 TI - [Phrmacodynamic principles underlying the specific therapy of coronary vascular disease]. PMID- 4144096 TI - [Free nucleotides of normal leukocytes and leukocytes in chromic leukemia]. PMID- 4144097 TI - [Free nucleotides of erythrocytes in proliferative diseases of the hemopoietic system]. PMID- 4144098 TI - Comparative fine structure of Cnidaria spermatozoa. PMID- 4144099 TI - [Pharmacological study of a new adrenergic beta receptor blocking agent: 1 isopropylamino-3-(1,2,3,4-tetrahydro-1,4-ethano-5-naphthoxy)-2-propanol hydrochloride (K4423)]. PMID- 4144100 TI - Acute haemodynamic effects of practolol in patients with idiopathic hypertrophic subaortic stenosis. PMID- 4144101 TI - [Cosmic medicine]. PMID- 4144102 TI - Determination of drug metabolizing enzymes in needle biopsies of human liver. PMID- 4144104 TI - Studies on the elimination reaction of D-amino acid oxidase with -amino- chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton. PMID- 4144103 TI - Some pharmacologic characteristics of the human vas deferens. PMID- 4144105 TI - Distrbution of enzymes between nucleus and cytoplasm of single nerve cell bodies. PMID- 4144106 TI - Studies on adrenal steroid hydroxylases. Molecular and catalytic properties of adrenodoxin reductase (a flavoprotein). PMID- 4144107 TI - Characterization of T7-specific ribonucleic acid polymerase. II. Inhibitors of the enzyme and their application to the study of the enzymatic reaction. PMID- 4144108 TI - Physician's assistant training program: questions & answers. PMID- 4144109 TI - Cardiac complications. Periarteritis nodosa of infancy. PMID- 4144111 TI - Grantsmanship in continuing education. PMID- 4144110 TI - Polyarteritis nodosa--an enigmatic disease. PMID- 4144112 TI - Evaluation in continuing education. PMID- 4144113 TI - Nurse practitioner: a new program in continuing education. PMID- 4144114 TI - Continuing education in nursing. PMID- 4144115 TI - Continuing education programs in nursing: an exploration. PMID- 4144116 TI - Training staffs multidimensional perceptions of a class of Medex (physician's extension) trainees: a method of grading. PMID- 4144117 TI - The undescended testicle. PMID- 4144118 TI - [Dental accidents in children and adolescents]. PMID- 4144119 TI - [The index of dental decay and of periodontal diseases in the infant population correlated to the fluorine content in the drinking water in the Covasna district]. PMID- 4144120 TI - Pharmacologic principles of gastrointestinal therapy. PMID- 4144121 TI - [Study of the aerobic bacterial flora isolated from sputum in chronic bronchial infections]. PMID- 4144122 TI - Release of the "ammonia effect" on three catabolic enzymes by NADP-specific glutamate dehydrogenaseless mutations in Saccharomyces cerevisiae. PMID- 4144123 TI - Oxidation of reduced triphosphopyridine nucleotide by submitochondrial particles from beef heart. PMID- 4144124 TI - Purification and properties of L(+)-lactate dehydrogenase from potato tubers. AB - 1. A purification of l(+)-lactate dehydrogenase is described. 2. The final preparation is active with NADH and NADPH and with a number of keto acids, but evidence is presented to support the view that a single enzyme is involved. 3. NAD(+) showed product inhibition, but at slightly acid pH values there was evidence of co-operative binding. 4. At acid pH values ATP was a potent inhibitor and appears to be an allosteric effector. At neutral or alkaline pH values ATP behaved as a weak competitive inhibitor. 5. The physiological significance of inhibition by ATP is discussed. PMID- 4144125 TI - [Symptomatic treatment of bronchial asthma]. PMID- 4144126 TI - International Congress on Mental Retardation. PMID- 4144127 TI - Effect of stimulators and inhibitors of hydrochloric acid secretion on numbers of oxidoreductase-positive gastric parietal cells in rats. PMID- 4144128 TI - Circulation, respiratory volumes and temperature regulation of the pigeon in dry and humid heat. PMID- 4144129 TI - Weight shifts in the intact turtle during heating and cooling. PMID- 4144130 TI - Activity recorded from the statocyst nerve of Pleurobranchaea californica during rotation and at different tilts. PMID- 4144131 TI - Structure-activity relationships of amino acid receptor sites on an identifiable cell body in the brain of the land snail Helix aspersa. PMID- 4144133 TI - Calorigenic effect of 5-hydroxytryptamine in the frog, Rana temporaria. PMID- 4144132 TI - Relationship between duodenal calcium-binding protein, parathyroid activity and various parameters of mineral metabolism in the rachitic and vitamin D-treated chick. PMID- 4144134 TI - Fluid and glucose movement across the small intestine in laboratory mammals. PMID- 4144135 TI - Evolution of the branchial sodium outflux and its components, especially the Na-K exchange and the Na-K dependent ATPase activity during adaptation to sea water in Anguilla anguilla. PMID- 4144136 TI - The absorption of inulin by cloacas and bladders in reptiles and the chicken. PMID- 4144137 TI - The role of adrenal corticosteroids in the regulation of kidney function in the desert lizard Dipsosaurus dorsalis. PMID- 4144138 TI - Acute effects on hypertonicity on the potential difference across the rumen wall in sheep. PMID- 4144139 TI - Blood chemistry of Roosevelt elk (Cervus canadensis roosevelti). PMID- 4144140 TI - Placental transfer of iron in the sow (Sus domesticus). PMID- 4144141 TI - Period of gestation and body weight in some placental mammals. PMID- 4144142 TI - [Phosphorus metabolism in salivary gland tissues under sialadenotrophic effect]. PMID- 4144143 TI - 3-Ketoglucose reductase of Agrobacterium tumefaciens. AB - Two kinds of 3-ketoglucose-reducing enzyme were partially purified from the sonic extract of Agrobacterium tumefaciens IAM 1525 grown on a sucrose-containing medium. Both enzymes have a specific requirement for reduced nicotinamide adenine dinucleotide phosphate (NADPH) as a hydrogen donor and catalyze the reduction of 3-ketoglucose to glucose but do not reduce 3-ketoglucosides such as 3 ketosucrose, 3-ketoglucose-1-phosphate, 3-ketotrehalose, and 3-ketocellobiose. From the requirement and substrate specificity of the enzymes, the name NADPH:3 ketoglucose oxidoreductase (trivial name, 3-ketoglucose reductase) was proposed. By diethylaminoethyl-cellulose column chromatography, two reductases were separated, and the early and late eluted enzymes were designated reductase I and II, respectively. K(m) values of reductase I and II were as follows: for 3 ketoglucose both had an identical value of 2.5 x 10(-5)m, and for NADPH the values were 1.0 x 10(-5)m and 1.5 x 10(-5)m, respectively. Optimal pH values were also identical: pH 4.8 to 5.0 in 10(-2)m phosphate buffer. Intracellular localization of the enzymes is discussed. PMID- 4144144 TI - Adenosine triphosphate-dependent deoxyribonuclease from Diplococcus pneumoniae: fate of transforming deoxyribonucleic acid in a strain deficient in the enzymatic activity. AB - The adenosine triphosphate-dependent deoxyribonuclease is required for wild-type levels of deoxyribonucleic acid (DNA) repair and genetic recombination. In an attempt to determine the physiological function of this enzyme in pneumococcal transformation, the fate of transforming DNA was followed in a wild-type strain and in a strain lacking the enzymatic activity. The qualitative and quantitative findings were closely comparable in the two strains through the step of physical association of a single strand of donor DNA with the recipient chromosome. These results are interpreted to mean that the enzyme may be involved in the subsequent hypothetical removal of excess polynucleotide sequences during conversion of the presumed hydrogen-bonded intermediate into a covalently linked recombinant structure. PMID- 4144145 TI - [Use of mathematical modeling to study regulation of cholesterol metabolism]. PMID- 4144147 TI - Neuroleptics and neurologic reactions. PMID- 4144146 TI - Effect of - and -adrenergic blocking agents and para-chlorophenylalanine on morphine- and caffeine-stimulated locomotor activity of mice. PMID- 4144148 TI - [Purulent meningitis. A 5-year patient material from Ulleval hospital]. PMID- 4144150 TI - [Scandinavian Association of Dental Students Summer-Congress 1969 in Bergen]. PMID- 4144151 TI - Mechanism of aromatic nitro group reduction in the soluble fraction of human placenta. PMID- 4144149 TI - [Serology of transplantation]. PMID- 4144152 TI - [Effect of a beta-blockader on postural arterial reflectivity in normal subjects]. PMID- 4144153 TI - [Effect of vasodilator agents on lipid metabolism and on platelet aggregation in humans]. PMID- 4144154 TI - Viral and bacterial neuraminidases. PMID- 4144155 TI - [Scandinavian Society of Dental Students--Summer Congress, Copenhagen August 20 27, 1972]. PMID- 4144156 TI - [Dental and periodontal injuries caused by removable partial dentures and means of prevention]. PMID- 4144157 TI - Hereditary methemoglobinemia associated with NADH diaphorase deficiency. PMID- 4144158 TI - Biennial Scientific Congress and 66th annual general meeting, East London, 13-17 September, 1971. Address by the president. PMID- 4144160 TI - Interactions of psychotropic drugs in the elderly. PMID- 4144159 TI - Hypothalamo-hypophyseal neurosecretory system in Rana temporaria in early ontogenesis. PMID- 4144161 TI - Management of respiratory allergy by nonallergists. 2. Asthma. PMID- 4144162 TI - [1st Congress for Dental Assistants as seen by participants--evaluation of the questionnaires shows interesting points]. PMID- 4144163 TI - Tardive dyskinesia: side effect or not? PMID- 4144164 TI - Comparison of the respiratory chain of Neurospora crassa wild type and the mi mutants mi-1 and mi-3. PMID- 4144165 TI - Incorporation of galactose into blood-groups(ABH) precursor substance by lactose synthetase from human milk. Effects on cross reactivity with anti-type-14 pneumococcus serum. PMID- 4144166 TI - Dihydropteridine reductase. Measurement of dissociation constants for binary complexes of enzyme and ligands. PMID- 4144167 TI - V Asian Pacific Congress of Cardiology: profile of plenary sessions. PMID- 4144168 TI - 5-Fluoropyrimidine-resistant mutants of pneumococcus. AB - Three classes of 5-fluorpyrimidine-resistant mutants of Diplococcus pneumoniae have been characterized. The mutant strain upp is resistant to high concentrations of the fluoropyrimidine bases fluorouracil (FU) and fluorocytosine (FC); strain upp has a defective uridine monophosphate pyrophosphorylase. The mutant strain udk is resistant to inhibition by fluorouridine (FUR) and exhibits defective uridine kinase activity. The mutant strain fun is resistant to inhibition by the nucleosides fluorodeoxyuridine, fluorodeoxycytidine, and FUR, but shows normal activity for all pyrimidine pathway enzymes tested. This strain may be defective in the activity of a transport system that governs the cellular uptake of pyrimidine ribo- and deoxyribonucleosides. Biochemical studies on wild type and fluoropyrimidine-resistant pneumococci are discussed with respect to the transport and early metabolism of preformed pyrimidine precursors by this organism. PMID- 4144169 TI - Selective utilization of pyrimidine deoxyribonucleosides for deoxyribonucleic acid synthesis in pneumococcus. AB - When pyrimidine deoxyribonucleosides are supplied to growing cultures of Diplococcus pneumoniae, they are selectively used for incorporation into deoxyribonucleic acid (DNA). Differently labeled molecules of deoxyuridine, thymidine, and deoxycytidine were used to study the precursor pathways of this organism. Each of these preformed pyrimidine deoxynucleosides is incorporated intact (i.e., without cleavage of the glycosidic bond) and is predominantly recoverable as DNA thymidine. During the utilization of deoxycytidine and deoxyuridine by pneumococci, large proportions of the available precursor are converted to free thymidine, which is secreted back into the growth medium. The biochemical pathways for selective incorporation into DNA and the regulation of concentrations of intracellular thymidine compounds by excretion of free thymidine are discussed. PMID- 4144170 TI - Development of circadian rhythm of hepatic tyrosine aminotransferase in growing rats. PMID- 4144171 TI - On the significance of anaphylactic catecholamine release in guinea pigs. PMID- 4144172 TI - Effect of 2-endo-aminonorbornane-2-carboxylic acid upon insulin secretion and fluorescence of reduced pyridine nucleotides of isolated perifused pancreatic islets. PMID- 4144173 TI - Phenobarbital inducible drug monooxygenase activity in the small intestine of mice. PMID- 4144174 TI - Enzymatic interconversion of active and inactive forms of enzymes. PMID- 4144175 TI - [Possibilities and limitations of influencing concentration disorders in school children with organic brain-induced reduced achievement capabilities]. PMID- 4144176 TI - Physical examination of four-year-old children. PMID- 4144177 TI - The mechanisms of nitrogen assimilation in pseudomonads. PMID- 4144178 TI - [Serum enzyme and isoenzyme changes in acute common bile duct diseases]. PMID- 4144179 TI - Turner-phenotype in males. PMID- 4144180 TI - [Drug therapy of angina pectoris]. PMID- 4144181 TI - [Epidemiology and prevention of coronary disease. 6th annual medical symposium, 23-24 March 1972]. PMID- 4144182 TI - Immunology in Hodgkin's disease. PMID- 4144183 TI - Pharmacokinetics of the -adrenergic blocker sotalol in dogs. PMID- 4144184 TI - Topical mosquito repellents. V. Benzyl ethers. PMID- 4144185 TI - 1,5-diphenyl-3-dimethylaminopyrrolidine: a long-acting histamine antagonist. PMID- 4144186 TI - [Elroquil in pediatric practice]. PMID- 4144187 TI - Histo- and bio-chemical observations on -glutamyl transpeptidase in liver diseases. PMID- 4144188 TI - Angina pectoris. Recent advances in understanding and implications for management. PMID- 4144190 TI - [Isolated periarteritis nodosa of the eye]. PMID- 4144189 TI - The adrenal dopamine as an indicator of adrenomedullary hormone biosynthesis. PMID- 4144191 TI - [Goodpasture's syndrome]. PMID- 4144192 TI - [Bacteriologic and clinical properties of minocycline]. PMID- 4144193 TI - [Extra-hospital pneumopathy due to pneumococci (aerobic and anaerobic) with septicemia]. PMID- 4144194 TI - On the role of sterol hydroperoxides in steroid metabolism. PMID- 4144195 TI - Functional components and mechanism of action of the resolved liver microsomal enzyme system catalyzing fatty acid, hydrocarbon and drug hydroxylation. PMID- 4144196 TI - On the significance of drug-induced spectral changes in liver microsomes. PMID- 4144197 TI - [Activities of the Scientific Council of the Ministry of Health of the Czech Socialistic Republic. (Report presented by the Chairman to the plenary meeting in June 1972)]. PMID- 4144198 TI - [Activities of the Scientific Council of the Ministry of Health of the Czech Socialistic Republic. (Report presented by the Chairman to the plenary meeting in December 1972)]. PMID- 4144199 TI - Ultrastructural changes in larval wax moth, Galleria mellonella, midgut and silk gland after exposure to chlorcyclizine, phenobarbital, or promazine. PMID- 4144200 TI - Survival of Toxoplasma gondii in mosquito cell lines and establishment of continuous infection in Vero cell cultures. PMID- 4144201 TI - [Experience in the work of the Feldsher Council]. PMID- 4144202 TI - In vitro bactericidal and associated metabolic activities of mouse spleen cells. AB - Spleen cell suspensions from AKR and CD-1 mice are able to kill Escherichia coli in vitro. The optimal ratio of splenocytes to bacteria for this activity is 1: 1. Incubation of these cells with inert polystyrene latex spherules (0.81 mum diameter) results in a fourfold increase in glucose-1-(14)C oxidation. Under these conditions, there is also a 2.5-fold increase in both reduced nicotinamide adenine dinucleotide phosphate oxidase activity and formate oxidation. Spleen cell fractions have been shown to have significant peroxidase activity. This has been quantitated by the guaiacol oxidation method. The 20,000 x g pellet fraction of spleen cell homogenate can kill E. coli when H(2)O(2) and chloride ions are added and the reaction is carried out at pH 5.5 and 37 C. PMID- 4144203 TI - Host factors and capsular typing of body fluid isolates in fulminant pneumococcal infections. AB - A 10-year retrospective study was made to determine the spectrum of underlying disease in, and the capsular types of pneumococci isolated from, blood and body fluids of 140 hospitalized patients. Fifteen serotypes were found among 82 typed isolates, 53% of which were types 8, 14, or 23. There was a predominance of males and a high incidence of underlying pneumonia, chronic liver disease, nephrotic syndrome, cerebrospinal fluid rhinorrhea, and malignancy. Mortality rates were higher among the very young and aged, and the immunologically comprised host at either extreme of life was more susceptible to disseminated pneumococcal infection. Pneumococci of the higher capsular types were prominent in children, and those of the lower types in adults, a finding in agreement with other recent studies. PMID- 4144204 TI - Clinical nutrition applications of space food technology. PMID- 4144205 TI - Skylab menu development. PMID- 4144206 TI - [Training of junior medical personnel in Byelgorod region]. PMID- 4144207 TI - [Contrast radiography in the diagnosis of maxillary sinusitis]. PMID- 4144208 TI - [How can one measure the activity of the orthosympathetic system in man?]. PMID- 4144209 TI - Undescended testes. PMID- 4144210 TI - [Experimental studies on decompression following diving in mountain lakes at reduced air pressure]. PMID- 4144211 TI - Freeze-dried bone as a meatal implant. PMID- 4144213 TI - The activity of sulphonamides and some other chemicals against mosquito larvae. PMID- 4144212 TI - Antigenicity of aortic valve allografts. PMID- 4144214 TI - Biting insects. PMID- 4144215 TI - [Reactivity of laboratory animals to repeated stings of mosquitoes (Anopheles labranchiae atroparvus). (Preliminary note)]. PMID- 4144216 TI - The effects of environmental isolation on behavior and regional rat brain tyrosine hydroxylase and tryptophan hydroxylase activities. PMID- 4144217 TI - Dental caries in English school children: a longitudinal study. PMID- 4144218 TI - A comparison of beta-blocking agents. PMID- 4144219 TI - Beta-adrenergic blockers in benign essential tremor. PMID- 4144221 TI - Even small hospitals need blood gases. PMID- 4144220 TI - Bovine lens -glutamyl transpeptidase. PMID- 4144222 TI - Herniagrams in undescended testes and hydroceles. PMID- 4144223 TI - Bromination of phenothiazine tranquiliziers: a method for sensitive and specific detection. PMID- 4144224 TI - [Tax problems of the physician in judgments of the Federal Finance Court of Justice]. PMID- 4144225 TI - Palpebral ptosis as an index of neuroleptic activity. PMID- 4144226 TI - Drug defaulting by patients on long-acting phenothiazines. PMID- 4144227 TI - [Abuse of travel sickness remedies among young drug addicts]. PMID- 4144228 TI - [Psychic factors in pulmonary tuberculosis]. PMID- 4144229 TI - [Malic acid metabolism in Saccharomyces. II. Partial purification and characteristics of a "malic" enzyme]. PMID- 4144230 TI - Purification and comparative properties of isoenzymes of nicotinamide-adenine dinucleotide phosphate-isocitrate dehydrogenase from rat heart and liver. AB - 1. Rat liver and heart major isoenzymes of NADP-isocitrate dehydrogenase have each been purified about 100-fold by a combination of ammonium sulphate fractionation and chromatography on ion-exchange cellulose and their properties compared. 2. The properties were similar in respect of pH, inhibition by Hg(2+) and Michaelis constants for isocitrate and NADP. 3. Some of the properties of the isoenzymes were different. 4. The heart isoenzyme was activated about 210% by 0.8m-ammonium sulphate whereas the liver isoenzyme was unaffected. The heart isoenzyme showed greater sensitivity to inactivation by heat (30 degrees C for 30min), whereas the liver isoenzyme was more sensitive to inactivation by p chloromercuribenzoate and by Cu(2+). 5. The Michaelis constants with 3 acetylpyridine-adenine dinucleotide phosphate showed a twofold difference between liver and heart isoenzyme. 6. The differential sensitivity to heat and its mainly non-cytoplasmic location may be an explanation of the failure of plasma isocitrate dehydrogenase activity to increase after a myocardial infarction. PMID- 4144231 TI - Relation between the oxidation state of nicotinamide-adenine dinucleotide and the metabolism of spermatozoa. AB - 1. The existing procedures for extraction of oxidized and reduced nicotinamide coenzymes were adapted to spermatozoa to overcome the coenzyme-degrading activity of seminal plasma. 2. The content of total NAD(+) and NADH was determined in the spermatozoa of ram, bull, boar, stallion and cock. NADP(+) and NADPH were not detected in ram spermatozoa. 3. The oxidation state of sperm NAD depended on the seminal plasma, the removal of which produced a change in the percentage oxidation state of the coenzyme, 100x[NAD(+)/(NAD(+)+NADH)], without altering the total content of NAD(+)+NADH. 4. In suspensions of washed ram spermatozoa, incubated anaerobically at 25 degrees C, the percentage oxidation state of NAD declined with increasing spermatozoa concentration. 5. When ram or boar spermatozoa that had been previously washed and resuspended in Ringer phosphate medium, were incubated anaerobically at 25 degrees C with various substances, pronounced effects on the percentage oxidation state of NAD could be observed with l-lactate, pyruvate, oxaloacetate, dihydroxyacetone, formaldehyde and glyceraldehyde; sorbitol and acetoacetate acted only on ram spermatozoa; fructose, glucose, mannose and acetaldehyde acted predominantly on boar spermatozoa. Formaldehyde lowered the (NAD(+)+NADH) content of ram spermatozoa, but none of the other substances had a comparable effect. 6. The percentage oxidation state of sperm NAD was not influenced by exogenous cysteine, cystine, ergothioneine or ascorbate. 7. A highly active sorbitol dehydrogenase could be prepared from ram, but not from boar, spermatozoa. 8. Sorbitol, acetoacetate and 3-hydroxybutyrate effectively supported the respiration of ram, but not boar, spermatozoa. 9. ;Cold shock', resulting from sudden cooling of spermatozoa, abolished motility completely and irreversibly but produced only a slow and partial decrease in the total NAD content. Slight over-heating, sufficient to produce loss of motility, had no adverse effect on the total NAD content. 10. Storage of ram sperm at 14 degrees C produced only a small decrease of NAD after 2 days, but subsequently the loss became greater. PMID- 4144232 TI - Inactivation of tyrosine aminotransferase in neutral homogenates and rat liver slices. AB - Inactivation of tyrosine aminotransferase induced in vivo by triamcinolone was studied in a homogenate incubated at neutral pH values. The integrity and the presence of subcellular particles together with a compartment of acidic pH are necessary for inactivation of tyrosine aminotransferase. It is suggested that tyrosine aminotransferase is inactivated inside lysosomes. The system responsible for inactivation of tyrosine aminotransferase was partially purified and identified with lysosomal cathepsins B and B(1). Inactivation of tyrosine aminotransferase in liver slices is controlled by the amino acid concentration and strongly stimulated by cysteine. 3,3',5-Tri-iodo-l-thyronine reversibly and strongly decreases the rate of inactivation of tyrosine aminotransferase. The effect is not due to an increased rate of tyrosine aminotransferase synthesis. PMID- 4144233 TI - Effect of halothane upon rabbit brain mitochondria. PMID- 4144234 TI - Effect of some 6-substituted benzo(a)pyrene derivatives upon liver enzymes and ascorbic acid excretion in mice. PMID- 4144235 TI - Effect of calcium, potassium and sodium on tyrosine hydroxylase activity in different regions of the rat brain. PMID- 4144236 TI - Two different effects of mutation on the binding of folate antagonists by a microbial dihydrofolate reductase. PMID- 4144238 TI - Purification and properties of NAD nucleosidase from Fusarium nivale. PMID- 4144237 TI - The inhibition of the Neurospora crassa nitrate reductase complex by metal binding agents. PMID- 4144239 TI - The effect of certain -adrenoceptor antagonists on overdrive suppression. AB - 1. Propranolol, as the racemate and the (+)- and (-)-isomers (400 mug/l.) and practolol (50 mg/l.) were tested for their effects on atrial and ventricular rates and on the duration of overdrive suppression (ODI) in isolated perfused cat hearts with surgically-induced heart block.2. Racemic propranolol and the (+)- and (-)-isomers prolonged ODI and slowed the rate of the ventricular pacemaker; the (+)- and (-)-isomers also reduced the rate of the atrial pacemaker. Practolol shortened ODI and increased the rate of the atrial and ventricular pacemakers.3. The (+)- and (-)-isomers were more potent than the racemate; the (-)-isomer was more potent than the (+)-isomer. The results suggest there is a stereospecific mechanism involved in the biological distribution of propranolol.4. Twenty-four hours after reserpine treatment (5 mg/kg, i.p.) practolol continued to increase the rate of the atrial and ventricular pacemakers but did not shorten ODI.5. The mechanism by which these agents affect myocardial excitability and automaticity is discussed. PMID- 4144240 TI - Pharmacological actions of a new -adrenoceptor agonist, MJ-9184-1, in anaesthetized cats. AB - 1. The effects of (-)-isoprenaline and the new beta-adrenoceptor agonist, MJ-9184 1, on the lungs, on the cardiovascular system, and on slow contracting skeletal muscle have been compared in cats under chloralose anaesthesia.2. Both amines reduced the increases in airways resistance produced by 5-HT, depressed incomplete tetanic contractions of the soleus muscle, lowered the blood pressure and produced an increase in heart rate. In comparison with (-)-isoprenaline, MJ 9184-1 had a long duration of action.3. The effects of MJ-9184-1 and (-) isoprenaline were antagonized by the beta-adrenoceptor antagonist, propranolol.4. MJ-9184-1 was approximately half as potent as (-)-isoprenaline in its effects on pulmonary resistance and soleus muscle contractility, and one seventh as potent in producing chronotropic effects in the heart.5. These results suggest that MJ 9184-1 possesses some specificity as a beta(2) receptor stimulant. PMID- 4144241 TI - The mechanism of the facilitatory action of edrophonium in cat skeletal muscle. AB - 1. The effects of edrophonium have been observed in the transversely cut tenuissimus muscle of the cat.2. Concentrations of edrophonium 10(-7)M to 10(-5)M increased the amplitude of the end-plate potential (e.p.p.) but produced no greater increase in time course than previously observed in curarized muscle.3. When the e.p.p. and gross nerve action potential were recorded simultaneously, antidromic discharges were observed in the motor nerve concomitantly with repetitive e.p.ps in the presence of edrophonium.4. Edrophonium produced no effect on the input resistance or equilibrium potential of the end-plate.5. The fractional release of transmitter was significantly increased by edrophonium but there was no increase in the quantal release of transmitter in the transversely cut muscle preparation.6. In curarized muscle edrophonium also increased the quantal release, the size of the available store of transmitter and the rate of refilling of the available store.7. It is concluded that edrophonium facilitates transmission to skeletal muscle by inducing a repetitive antidromic discharge in the nerve, following orthodromic stimulation. The antidromic discharge propagates by axon reflex to other nerve terminals of the same motor unit producing repetitive e.p.ps. It is also suggested that edrophonium antagonizes tubocurarine by acting as a partial agonist at the motor nerve terminal. PMID- 4144242 TI - Antagonism of some spasmogens of the rat seminal vesicle. PMID- 4144243 TI - The effects of B2-adrenoceptor stimulants, salbutamol and terbutaline on gastric acid secretion and mucosal blood flow in conscious dogs with Heidenhain pouches. PMID- 4144244 TI - Cutaneous polyarteritis. PMID- 4144245 TI - Osteomalacia after prolonged glutethimide administration. AB - Vitamin D deficiency is a previously unreported complication of therapy with hypnotics, and we here report a case of osteomalacia associated with long-term glutethimide administration. There was evidence of pronounced hepatic enzyme induction, and the plasma half-time of (3)H vitamin D(3) was decreased by this drug. In addition, raised levels of serum gamma-glutamyl transpeptidase, 5 nucleotidase, and leucine aminopeptidase were observed and the patient excreted large amounts of xylulose. These changes were reversed by stopping the glutethimide. PMID- 4144246 TI - Mode of action of verapamil. PMID- 4144247 TI - Progressive increase in cell-mediated immunity against paternal transplantation antigens in parous mice after multiple pregnancies. PMID- 4144248 TI - Vasodilator drugs and peripheral vascular disease. PMID- 4144249 TI - Beta-blocking drugs and human platelet aggregation in vitro. PMID- 4144251 TI - [Antimicrobial activity of 1,2,4-benzothiadiazine-1,1-dioxide derivatives. II]. PMID- 4144250 TI - Influence of anticholinergic-antiparkinsonian agents on the effects of narcoanalgesic drugs in the rat. PMID- 4144252 TI - [Polyateritis nodosa with neurological complication in an infant]. PMID- 4144253 TI - [Histamine receptors]. PMID- 4144254 TI - Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. I. The Escherichia coli hemoflavoprotein: molecular parameters and prosthetic groups. PMID- 4144255 TI - Specific binding of -adrenergic catecholamines to a subcellular fraction from cardiac muscle. PMID- 4144256 TI - Survival of irradiated hybrid female mice inoculated with maternal bone marrow: a preliminary report. PMID- 4144257 TI - [Reinsertion of the deep flexor tendon]. PMID- 4144258 TI - [Experiences with the management of vascular injuries]. PMID- 4144259 TI - [The importance of repeated venography in the treatment of femoral neck fractures]. PMID- 4144260 TI - [Early results of the intertrochanteric variating-derotating osteotomies in childhood]. PMID- 4144261 TI - [Experiences in the surgical treatment of habitual shoulder dislocation]. PMID- 4144262 TI - [Routine osteosynthesis of isolated unstable radius fractures]. PMID- 4144263 TI - [Experience with the treatment of arm paralysis caused by birth injury]. PMID- 4144264 TI - [Latent blood loss in closed femoral or pelvic fractures]. PMID- 4144265 TI - [Traumatic pelvic apophyseolysis in the pelvic area]. PMID- 4144266 TI - [Mercury as foreign body in the hand]. PMID- 4144267 TI - [5-year survival of a patient with Ewing's sarcoma]. PMID- 4144269 TI - [Some questions concerning traumatologic roentgen examinations]. PMID- 4144268 TI - [Unusual surgical management of fractured dislocation of the hip]. PMID- 4144270 TI - Biochemical aspects of drug and hormone action on adipose tissue. PMID- 4144272 TI - [The nervous system of ctenophores. I. Structure and ultrastructure of the epithelial nerve-nets]. PMID- 4144271 TI - [Clinical studies on extracorporeal circulation with increased hemodilution. II. Oxygen utilization with special reference to optimal flow rate]. PMID- 4144273 TI - Tritiated thymidine uptake by in vitro spleen lymphoid cell cultures following stimulation by GC murine leukemia virus. PMID- 4144274 TI - Uridine kinase level in cells infected with western equine encephalomyelitis, vesicular stomatitis, pseudorabies and polyoma viruses. PMID- 4144275 TI - Dynamics of accumulation of capsid proteins of type 1 adenovirus (immunofluorescence and cytofluorometric data). PMID- 4144276 TI - Effect of lysozyme from human placenta on ectromelia virus. PMID- 4144277 TI - Penetration of Venezuelan equine encephalomyelitis virus into the brain of guinea pigs and rabbits after intranasal infection. PMID- 4144278 TI - Continuously recording photometry of fluorescence-labelled objects. PMID- 4144279 TI - Interferon induced by tumoral DNA in a homologous system. PMID- 4144280 TI - A complex natural focus of arboviruses on Glinyanyi Island, Baku Archipelago, Azerbaidzhan S.S.R. PMID- 4144281 TI - Interferon production and infection caused by vesicular stomatitis virus in radiation chimeras. PMID- 4144282 TI - Contribution to the problem of purity of interferon preparations. PMID- 4144283 TI - Friend leukemia virus (FLV) elimination in feces of flies and fleas. PMID- 4144284 TI - Continual serum interferon induced by prolonged drinking of tiloron solution. PMID- 4144285 TI - On the "neuropathogenicity" mechanism of vaccinia virus. PMID- 4144286 TI - Anti-interfering and anti-interferon-inducing properties of adenociral soluble antigens. PMID- 4144287 TI - A case of subacute sclerosing panencephalitis. PMID- 4144288 TI - Nuclear basic proteins of polyoma virus-infected cells cultivated in vitro. PMID- 4144289 TI - Metabolism of skeletal muscle following incomplete ischemia. PMID- 4144290 TI - -Glutamyl transpeptidase from Aspergillus terricola. PMID- 4144291 TI - The pathogenesis of the graft-versus-host reaction in chicken embryos. Pathological changes in the yolk sac, thymus, bone marrow and bursa of Fabricius. PMID- 4144292 TI - Changes in levels of tissue nucleotides and glutathione after hyperbaric oxygen treatment. PMID- 4144293 TI - Fat metabolism in higher plants. Beta-hydroxylation of fatty acids by a soluble preparation from maturing avocado mesocarp. AB - 1. An avocado supernatant fraction converted fatty acids of medium chain length (C(8)-C(12)) into a polar product. 2. The product was identified as the beta hydroxy derivative of the substrate by g.l.c. and t.l.c. analysis. 3. For hydroxylation of the fatty acids, CoA, ATP and molecular oxygen were required. Acyl carrier protein gave some stimulation. The reaction took place with oxygen alone if acyl-CoA was the substrate. 4. Hydroxylation was maximal with decanoic acid but dodecanoic acid and octanoic acid were also very active. Acids of shorter or longer chain lengths were not hydroxylated. 5. NAD(+) concentration caused complete inhibition at 0.5mm and may be an important control mechanism for the reaction in vivo. 6. The reaction was inhibited by iodoacetamide and by bipyridyl and carbon monoxide, indicating involvement of thiol and heavy metal groups. PMID- 4144295 TI - Adenine derivatives as neurohumoral agents in the brain. The quantities liberated on excitation of superfused cerebral tissues. AB - Adenine nucleotides of guinea-pig neocortical tissues were labelled by incubation with [(14)C]adenine and excess of adenine was then removed by superfusion with precursor-free medium. Adenine derivatives released from the tissue during continued superfusion, including a period of electrical stimulation of the tissue, were collected by adsorption and examined after elution and concentration. The stimulation greatly increased the (14)C output, and material collected during and just after stimulation had a u.v. spectrum which indicated adenosine to be a major component. The additional presence of inosine and hypoxanthine was shown by chromatography and adenosine was identified also by using adenosine deaminase. Total adenine derivatives released from the tissue during a 10min period of stimulation were obtained as hypoxanthine, after deamination and hydrolysis of adenosine and inosine, and amounted to 159nmol/g of tissue. This corresponded to the release of approx. 7pmol/g of tissue per applied stimulus. The hypoxanthine sample derived from superfusate hypoxanthine, inosine and adenosine was of similar specific radioactivity to the sample of inosine separated chromatographically, and each was of higher specific radioactivity than the adenine nucleotides obtained by cold-acid extraction of the tissue. PMID- 4144296 TI - Studies on urticaria pigmentosa. PMID- 4144294 TI - Proton translocation coupled to quinone reduction by reduced nicotinamide- adenine dinucleotide in rat liver and ox heart mitochondria. AB - Measurements were made of the stoicheiometry of proton-translocation coupled to NAD(P)H oxidation by several quinones (duroquinone, ubiquinone(0), ubiquinone(1), ubiquinone(2)) in mitochondria from rat liver and ox heart. Observed stoicheiometries of protons translocated per mol of NADH oxidized (-->H(+)/2e(-) ratios; Mitchell, 1966) ranged from 0.75 (rat liver mitochondria with ubiquinone(1)) to 1.55 (ox heart mitochondria with ubiquinone(1) or ubiquinone(2)). Only the rotenone-sensitive pathway of NADH oxidation by quinone was able to support proton translocation. Correction of the observed -->H(+)/2e( ) ratios for the loss of reducing equivalents to the rotenone-insensitive pathway increased their value to approx. 2.0. It is concluded that the rotenone-sensitive NADH- ubiquinone reductase activity of the respiratory chain may be organized in the mitochondrial membrane as a proton-translocating oxidoreduction loop. The number of such loops between NADH and ubiquinone is one, and not two, as initially proposed by Mitchell (1966). PMID- 4144298 TI - Blood lymphocyte nuclei activation and skin allograft rejection in mice. PMID- 4144297 TI - Analysis of the role of H-2 genotypic and phenotypic differences in the spleen colony formation and lymphatic follicle repopulation by bone marrow cells. PMID- 4144299 TI - Perforated jejunum due to primary Hodgkin's disease. PMID- 4144300 TI - Viral labyrinthitis and transient phrenic nerve paralysis. PMID- 4144301 TI - Jaundice due to urinary tract infection. PMID- 4144302 TI - Immediate transfusion reaction: fact and fancy. PMID- 4144303 TI - Psychiatric emergencies of childhood and adolescence. PMID- 4144304 TI - Gas masks permit identification of exhumed corpse. PMID- 4144305 TI - Ureteral tumor. PMID- 4144306 TI - Guided non-visualized nasal endotracheal intubation using a transtracheal Fogarty catheter. PMID- 4144307 TI - Enigmatic fever during hemodialysis. PMID- 4144308 TI - Fetal breathing movements. PMID- 4144309 TI - Deficit of specific thymus-dependent lymphocytes in transplantation tolerance in the rat. AB - Recovery from adoptively terminated transplantation tolerance was studied by utilizing formerly tolerant rats as donors of lymphocytes in local renal graft vs.-host reactions (GVHR). The origin of the proliferating lymphocytes in the GVHR was studied by means of sex chromosome markers. A deficit of specifically reactive lymphocytes, while tolerance was in effect, was revealed by the continuing absence of autochthonous specifically reactive cells after tolerance was abolished in adult thymectomized chimeras. The findings are consistent with Burnet's hypothesis of the cellular basis of tolerance, but apply only to the T lymphocytes of donor origin which normally proliferate in these GVHR. PMID- 4144310 TI - The changing nature of respiratory diseases in industry. PMID- 4144311 TI - Adrenal and striatal tyrosine hydroxylase activity after methamphetamine. PMID- 4144312 TI - [The disease panorama, as revealed by drug prescription data]. PMID- 4144313 TI - The storage of noradrenaline in sympathetic ganglia. PMID- 4144314 TI - Effect of adrenergic reactive drugs on Tetrahymena pyriformis in a chemically defined medium. PMID- 4144315 TI - Catecholamines: strain differences in biosynthetic enzyme activity in mice. PMID- 4144316 TI - Norepinephrine: dissociation of -receptor binding from adenylate cyclase activation in solubilized myocardium. PMID- 4144317 TI - Effects of chronic ethanol feeding on enzymes of rat brain and liver mitochondria. PMID- 4144318 TI - Pharmacological therapy of angina pectoris. PMID- 4144319 TI - [Clinical aspects and treatment of toxic dilatation of the colon]. PMID- 4144320 TI - Necrotizing angiitis in a methamphetamine user with hepatitis B--angiographic diagnosis, five-month follow-up results and localization of bleeding site. PMID- 4144321 TI - Undescended testes. PMID- 4144322 TI - Does cyclic-3',5'-AMP induce glutamine synthetase in embryonic neural retina? PMID- 4144323 TI - The presence of the glycerol phosphate shuttle and energy dependent transhydrogenase in aortic mitochondria. PMID- 4144324 TI - Active oxidative decarboxylation of malate by mitochondria isolated from L-1210 ascites tumor cells. PMID- 4144325 TI - Chlorcyclizine N-demethylase activity in chick embryo hepatic cell culture. PMID- 4144326 TI - Low magnitude transformation of estradiol to estrone in human endometrium. PMID- 4144327 TI - Studies on peroxisones. 3. Further studies on the intraparticulate localization of peroxisomal components in the liver of the rat. PMID- 4144328 TI - Redistribution of pyridoxal phosphate in the male rat liver as a result of repeated injections of hydrocortisone. PMID- 4144329 TI - Occurrence of N-malonyl-D-alanine in pea seedlings. PMID- 4144330 TI - The effect of innervation, denervation, and muscle type on the reunion of skeletal muscle. PMID- 4144331 TI - The controlled use of vasodilator drugs in the management of hypovolaemia complicated by diminished cardiac function. PMID- 4144332 TI - Pharmacodynamic studies of beta adrenergic antagonism induced in man by propranolol and practolol. AB - The pharmacodynamic activities of two beta adrenergic antagonists, propranolol and practolol, were compared in eight hypertensive patients. The activity of each antagonist was established in relation to its blood concentration at maximal and submaximal adrenergic blockade defined by inhibition of exercise tachycardia. Maximal inhibition of exercise tachycardia was comparable with both drugs and averaged 74+/-7% of the control value during drug treatment. This inhibition was achieved with a blood concentration of 2.5+/-0.4 mug/ml practolol and 0.10+/-0.08 mug/ml propranolol. The antagonist activities of these drugs against adrenergic stimulation with isoproterenol infusion indicated a much greater relative potency of propranolol against this stimulus, and in vivo estimates of PA(2) values differed by more than 600-fold. Relative antagonist activity of practolol during isoproterenol stimulation was equivalent both at cardiac (inotropic and chronotropic) and at vascular adrenergic receptors, whereas greater antagonist activity of propranolol was observed at vascular receptors than at cardiac receptors. Thus, the activity of practolol was not limited to cardiac receptors as previously suggested. Practolol did not reduce cardiac output at any dose level and the effect on resting blood pressure was small. Both practolol and propranolol had much greater hypotensive activity during exercise. These studies have defined the differing pharmacodynamic activities on the cardiovascular system of two effective beta adrenergic receptor antagonists and have established the blood levels of these antagonists necessary to achieve effective adrenergic blockade. PMID- 4144333 TI - [Activities of intrahepatic ammonia detoxication enzymes in hepatic coma]. PMID- 4144334 TI - Teaching medical assistants for the doctor. PMID- 4144335 TI - Neurologic manifestations of conductive--tissue disease. PMID- 4144336 TI - [Adrenergic broncholytic agents. Different causes and symptoms of adverse effects]. PMID- 4144337 TI - [Anaphylactic shock during anesthesia induced by oxypolygelatin]. PMID- 4144338 TI - Effects of radiation on hematopoietic tissue. PMID- 4144339 TI - Temperature-dependent reaction of flufenamic acid with rat erythrocyte membrane. PMID- 4144340 TI - [The mode of action of a plasma factor which diminishes the activity of histamine on isolated guinea pig ileum]. PMID- 4144341 TI - Strain differences in the ability of antithymocyte serum (ATS) to enhance the antibody response of inbred mice to type 3 pneumococcal polysaccharide. PMID- 4144342 TI - Age-related pathologic changes, hypertension, and 18-hydroxydeoxycorticosterone in rats selectively bred for high or low juxtaglomerular granularity. PMID- 4144343 TI - An abnormality of the alternate pathway of complement activation in sickle-cell disease. PMID- 4144344 TI - The training of physician's assistants. The use of a clinical algorithm system for patient care, audit of performance and education. PMID- 4144345 TI - Sickle-cell disease and the properdin system. PMID- 4144346 TI - Algorithms, anyone? PMID- 4144347 TI - The effect of anions on the oxidase activity of rat ceruloplasmin. PMID- 4144349 TI - Drug-induced pulmonary disease. PMID- 4144348 TI - Quantification of human seminiferous epithelium. 3. Histological studies in 44 infertile men with normal chromosome complements. PMID- 4144350 TI - [Association of sexual ambiguity and hypopituitarism]. PMID- 4144351 TI - Effect of practolol on the extent of myocardial ischaemic injury after experimental coronary occlusion and its effects of ventricular function in the normal and ischaemic heart. PMID- 4144352 TI - Cardiospecificity of -receptor blockade. A comparison of the relative potencies on cardiac and peripheral vascular -adrenoceptors of propranolol, of practolol and its ortho-substituted isomer, and of oxprenolol and its para-substituted isomer. PMID- 4144353 TI - [Disorders due to changes of pressure-dysbarism--in hypobaric chamber]. PMID- 4144354 TI - Corticosteroid-sparing effect of -adrenergic blocking agents in pemphigus vulgaris. PMID- 4144355 TI - Initiation of aerobic oxidation of sulfite by illuminated spinach chloroplasts. PMID- 4144356 TI - Mechanism of enzymatic reduction of steroid double bonds. PMID- 4144357 TI - [Study of L-dopa treatment and its principal side effects in aged subjects]. PMID- 4144358 TI - Nucleus-associated 5 -reductase activity in the rat. PMID- 4144359 TI - Interaction of the central nervous system with the endocrine system in thermoregulation in baboons. PMID- 4144360 TI - Studies of aqueous humor dynamics in man. 3. Measurements in young normal subjects using norepinephrine and isoproterenol. PMID- 4144361 TI - Structural factors influencing outflow facility and its changeability under drugs. A study in Macaca arctoides. PMID- 4144362 TI - Behavior setting utilization by emotionally disturbed college students. PMID- 4144363 TI - Behavioral correlates for the Minnesota Multiphasic Personality Inventory 4-9, 9 4 code types: a case of the emperor's new clothes? PMID- 4144365 TI - The certifying of physicians' assistants. PMID- 4144364 TI - A comparison of defectors and continuers in a child guidance clinic. PMID- 4144366 TI - [Management of patients with unexplained gastrointestinal hemorrhage]. PMID- 4144367 TI - Effects of cannabis and alcohol on psychological tests. PMID- 4144368 TI - [Determination of the insecticide effect using biological and chemical methods]. PMID- 4144369 TI - [Early diagnosis of abnormalities in the newborn infant]. PMID- 4144370 TI - 2-Nitrilophenoxypropanolamines: -adrenoreceptor antagonism in the rat. PMID- 4144372 TI - Electrophysiological evaluation of anesthetic actions of some beta-adrenergic blockers on guinea-pig cardiac muscles. PMID- 4144371 TI - Pharmacological studies on 1-(7-indenyloxy)-3-isopropylaminopropan-2-Ol hydrochloride (YB-2), a new -adrenergic blocking agent. PMID- 4144373 TI - Mechanism studies of gastric inhibition by glucagon: failure of KCl and adrenergic blocking agents to prevent its action. PMID- 4144374 TI - Facial sweating after food: a new sign of diabetic autonomic neuropathy. AB - Facial sweating during eating (gustatory sweating) has been observed for the first time in a group of diabetics, and is considered to be a feature of the autonomic neuropathy which affected them all. The sweating, which was sometimes very severe, was produced by many foodstuffs, cheese being the most powerful stimulus. Atropine inhibited sweating stimulated by eating cheese, and oral anticholinergic drugs effectively eliminated the symptoms. These bizarre symptoms are probably due to abnormal nerve regeneration occurring as a consequence of the spontaneous autonomic neuropathy. PMID- 4144375 TI - Familial occurrence of persistent Mullerian structures in otherwise normal males. AB - Eight cases of males with persistent Mullerian structures are reported in four pairs of unrelated siblings. A genetically inherited failure to produce or to respond to the Mullerian-inhibiting substance elaborated by the fetal testis is postulated. PMID- 4144376 TI - Cytological study of the gut cells of the larvae of mosquito vectors. PMID- 4144378 TI - Bender-Gestalt constriction as an indicator of depression in psychiatric patients. PMID- 4144377 TI - Spasmolytic effect of polysorbates (Tweens) 80 and 20 isolated tissues. PMID- 4144379 TI - MMPI correlates with locus of control in a psychiatric population. PMID- 4144380 TI - Clinical judgment: the effects of statistical information. PMID- 4144381 TI - [Peroral desensitization of inhalation allergies in childhood: treatment results]. PMID- 4144382 TI - [Data on the participation of veterinarians at the 1st Congress of Serbian Doctors and Naturalists in the year 1904]. PMID- 4144383 TI - Nocturnal man-biting mosquitoes of urban and rural areas. PMID- 4144384 TI - Localised histoplasmosis treated with amphotericin. PMID- 4144385 TI - Mesenteric vascular insufficiency. Identification and management. PMID- 4144386 TI - Viral encephalitis. PMID- 4144388 TI - Regulation of oxalacetate metabolism in liver mitochondria. Evidence for nicotinamide adenine dinucleotide-malate dehydrogenase equilibrium and the role of phosphoenolpyruvate carboxykinase in the control of oxalacetate metabolism in intact guinea pig and rat liver mitochondria. PMID- 4144387 TI - Modern functional morphology of the equine lung. PMID- 4144389 TI - The effects of cycloheximide on energy transfer in rat and guinea pig liver mitochondria. PMID- 4144390 TI - Inhibition of induction of rat liver tyrosine aminotransferase by D galactosamine. PMID- 4144391 TI - A mechanism for the regulation of nicotinamide adenine dinucleotide-linked substrate oxidation in rat liver mitochondria. PMID- 4144392 TI - Intranuclear binding of 17 -estradiol and estrone in female ovine pituitaries following incubation with estrone sulfate. PMID- 4144393 TI - Nicotinamide adenine dinucleotide- and nicotinamide adenine dinucleotide phosphate-specific glucose 6-phosphate dehydrogenases of Acetobacter xylinum and their role in the regulation of the pentose cycle. PMID- 4144394 TI - Enzymatic synthesis of plasmalogens. Characterization of the 1-O-alkyl-2-acyl-8n glycero-3-phosphorylethanolamine desaturase from mucosa of hamster small intestine. PMID- 4144396 TI - Contact inhibition and gene expression in HTC-L cell hybrid lines. PMID- 4144395 TI - Biosynthesis of bacterial glycogen. XI. Kinetic characterization of an altered adenosine diphosphate-glucose synthase from a "glycogen-excess" mutant of Escherichia coli B. PMID- 4144397 TI - Evidence for similar biochemical requirements for bioluminescence among the coelenterates. PMID- 4144398 TI - Effects of neurotransmitters on the hepatic blood flow in dogs. PMID- 4144399 TI - Revamping the health care team. PMID- 4144400 TI - The training and role of physicians' assistants in the Army Medical Department. PMID- 4144401 TI - [Interactions between drugs and food]. PMID- 4144402 TI - Effect of immunosuppressive drugs on a localized graft-versus-host reaction in the rat. PMID- 4144403 TI - On the enzymology of amino acid transport. PMID- 4144404 TI - [Encephalitis following smallpox vaccination]. PMID- 4144405 TI - Familial hyperparathyroidism. Mild hypercalcemia in at least nine members of a kindred. PMID- 4144406 TI - What one internist does in his practice. Implications for the internist's disputed role and education. PMID- 4144408 TI - Cellular immunity and blocking serum activity in chimeric mice. PMID- 4144407 TI - Effect of stellate ganglion stimulation on myocardial blood flow, oxygen consumption, and cardiac efficiency during beta-adrenoceptor blockade. PMID- 4144409 TI - [False transmitter substances in brain. Selective, chemically induced degeneration of monoaminergic neuron systems: a new method for neuroanatomy and neuropharmacology]. PMID- 4144410 TI - Menaquinone function in the electron transport system of an antibiotic-producing strain of Bacillus brevis. PMID- 4144411 TI - Artificial testicles in children: a new silastic gel testicular prosthesis. PMID- 4144412 TI - Prevalence of neoplasms and causes of death in paralysis agitans. A necropsy study. PMID- 4144413 TI - Assessment of the radioprotective capacity of spleen cells transplanted from mice with Rauscher viral leukemia. PMID- 4144414 TI - The role of amine mechanisms in the vasomotor regulation of intracranial arteries. PMID- 4144415 TI - Emetic effect of biogenic amines. PMID- 4144416 TI - The development of new antidysrhythmic drugs. PMID- 4144417 TI - [Modern therapy of cardiac arrhythmias]. PMID- 4144418 TI - [Hemodynamic effects of dipyridamole (Persantin) following beta-blockade in coronary failure]. PMID- 4144419 TI - [Achievements of roentgenology and radiology in the Lithuanian SSR in the years of Soviet rule]. PMID- 4144420 TI - Clinical assessment of practolol in coronary heart disease. PMID- 4144421 TI - Excretion of catecholamines, corticosteroids and 5-HIAA as related to the testing conditions, physical fitness and psychological variable of healthy sunjects. PMID- 4144422 TI - Analysis of the hemodynamic action of beta-adrenolytics in narcotized cats. PMID- 4144423 TI - Methodological issues in measuring ambulatory care. PMID- 4144424 TI - Effects of practolol on pressor responses to noxious stimuli in hypertensive patients. PMID- 4144425 TI - Practolol in patients with angina pectoris. PMID- 4144426 TI - Insulin and Sepharose-insulin effects on tyrosine transaminase levels in cultured rat liver cells. PMID- 4144427 TI - Effect of some adrenergic beta-receptor antagonists on the act ion of d tubocurarine and pancuronium bromide. PMID- 4144428 TI - [Psychopharmacological and psychopathological value of a neurophysiological study of the effect of a major neuroleptic drug on the interspecific agressive behavior of rats and mice and on the systems of reinforcement of the rat]. PMID- 4144429 TI - The relationship of personality to tolerance of an irritant compound. PMID- 4144430 TI - The physician's assistant in a psychiatric hospital. PMID- 4144431 TI - [Physician, house calls and physicians' assistants]. PMID- 4144432 TI - Nymphomania--a symptom. II. Psychoses. PMID- 4144433 TI - Synthesis of some 4-substituted amino-1-methylpiperidines structurally related to antihistaminics. PMID- 4144434 TI - Gastric mucosal damage induced by non-steroid anti-inflammatory agents in rats of different ages. PMID- 4144435 TI - Influence of isolation and of fighting on adrenal tyrosine hydroxylase and phenylethanolamine-N-methyltransferase activities in three strains of mice. PMID- 4144436 TI - Steroids. XX. Non-specific enzymic hydroxylation of aromatic steroids. 19. In vitro hydroxylation and transformations. PMID- 4144437 TI - Assays of tissual NADP by means of the recycling system composed of isocitrate dehydrogenase and glutathione reductase. PMID- 4144438 TI - [Spectrophotometric determination of 4-chlorophenoxyacetic acid dimethylaminoethyl ester hydrochloride]. PMID- 4144439 TI - Enhancement by cystamine of formation of thiols by liver cytoplasmic enzymes. PMID- 4144440 TI - Long-term immunosuppressive therapy of ulcerative colitis. Continuation of a personal series. PMID- 4144441 TI - Acquired resistance to beta stimulants: a possible explantion for the rise in the asthma death rate in Britain. PMID- 4144442 TI - In vivo and in vitro studies on alpha-receptors in human airways; potentiation with bacterial endotoxins. PMID- 4144443 TI - Effects of practolol on respiratory and cardiovascular responses to isoproterenol in normal and asthmatic subjects. PMID- 4144444 TI - Electrophoretic variation in glutamate dehydrogenase and other isozymes in wild carrot cells cultured in the presence and absence of 2,4-dichlorophenoxyacetic acid. PMID- 4144445 TI - Gas-liquid chromatography of phenothiazine derivatives and related compounds. PMID- 4144446 TI - [Etiology of angiocholitis]. PMID- 4144447 TI - [Medical approach to angiocholitis. General treatment and antibiotic therapy]. PMID- 4144448 TI - [Angiocholitis with acute renal failure]. PMID- 4144449 TI - [Surgical procedure in angiocholitis (apropos of a series of 77 patients operated on over a 3-year period)]. PMID- 4144450 TI - [Cholangitis, Practical conclusions]. PMID- 4144451 TI - [Errors and complications of the surgical treatment of cryptorchism]. PMID- 4144452 TI - Renal abnormalities in the Russell-Silver syndrome. PMID- 4144453 TI - Hyperdibasicaminoaciduria in a mentally retarded homozygote with a peculiar response to phenothiazines. PMID- 4144455 TI - Cryptorchidism in the newborn. PMID- 4144456 TI - Functional properties of segregated lymphocytes. PMID- 4144454 TI - Antihistamines in topical preparations. PMID- 4144457 TI - Diversity of T cells recognizing transplantation antigens: mechanism of antigen recognition. PMID- 4144458 TI - Characteristics of histocompatibility barriers in congenic mice. PMID- 4144459 TI - Immune responsiveness and active enhancement of rat renal allografts with soluble specific antigen. PMID- 4144460 TI - The reactivity of blood lymphocytes from actively enhanced rats. PMID- 4144461 TI - The cellular basis of transplantation tolerance. PMID- 4144462 TI - Specific immunosuppression of cardiac allograft rejection in rats. PMID- 4144463 TI - Tolerance reconsidered--a critical survey. PMID- 4144464 TI - Transplantation of neonate thymus-sternum complex in ataxia-teleangiectasia. PMID- 4144465 TI - Specific depletion of GVH reactivity of mouse lymphocytes by adsorption on allogeneic fibroblast monolayers. PMID- 4144466 TI - Inhibition of allograft reactivity in vitro and in vivo, by Fab fragments obtained from ALG. PMID- 4144467 TI - Prevention of graft-versus-host disease by Fab fragments derived from ALG. PMID- 4144469 TI - Recent advances in transplantation of incompatible marrow in infants with combined immunodeficiency disease. PMID- 4144468 TI - Specific inactivation of lymphoid cells in bone marrow grafts. PMID- 4144470 TI - Immunologic reconstitution in severe combined immunodeficiency with HL-A incompatible bone marrow graft: donor selection by mixed lymphocyte culture. PMID- 4144471 TI - The use of stem cell concentrates as bone marrow grafts in man. PMID- 4144472 TI - Aplastic anemia treated by marrow transplantation. PMID- 4144473 TI - Marrow grafting in patients with acute leukemia. PMID- 4144475 TI - Viral etiology of immunologically induced lymphomas. PMID- 4144474 TI - Progress in the prevention of GVH: bone marrow grafts after ALG conditioning, with lymphocyte split chimerism, use of a lymphocyte "chalone T", and soluble histocompatibility antigens. PMID- 4144476 TI - [Ten years of pedodontist service in the rural district of Calw]. PMID- 4144477 TI - [Activity of some oxidative-reductive enzymes in the epithelium of the pathologically altered cervix uteri]. PMID- 4144478 TI - Vitamin E protection of membrane lipids during electron transport functions. PMID- 4144479 TI - Thymic carcinoid in familial multiple endocrine adenomatosis. PMID- 4144480 TI - Transamination of ring-substituted L-phenylalanines by an extract from rat liver mitochondria. PMID- 4144482 TI - Photoperiodism in Orthopodomyia signifera. PMID- 4144481 TI - Enzyme activities during culturing of fetal rat liver. PMID- 4144483 TI - Effects of adrenergic blockers on the relaxation of the guinea-pig ileum by bradykinin and adrenaline. PMID- 4144484 TI - Comparison of therapeutic and toxic actions of ouabain, gitoxin and 16-epi gitoxin on isolated atria at different extracellular potassium concentrations. PMID- 4144485 TI - Central cardiovascular effects of intracerebroventricular propranolol. PMID- 4144487 TI - Two-substituted aminomethylquinolines & 1,2,3,4-tetrahydroquinolines & 3 substituted 2,3,4,4a,5,6-hexahydro(1-H) pyrazino(1,2-a)quinolines--a new class of alpha-adrenoceptor blocking agents. PMID- 4144486 TI - Effect of 9 -tetrahydrocannabinol on immobilization-induced changes in rat adrenal medullary enzymes. PMID- 4144488 TI - The Institute of Hospital Dental Service. PMID- 4144489 TI - National Dental Health Conference explores peer review, manpower planning, responsibility of consumers. Council on Dental Health, Council on Dental Care Programs. PMID- 4144490 TI - Visual test for erythrocytic glucose-6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, and glutathione reductase deficiencies. PMID- 4144491 TI - [Clinical aspects of transplantation of the testicle. I. Indications for the operation and methods of diagnosis]. PMID- 4144492 TI - Quellung test for pneumonia. PMID- 4144493 TI - Liver enlargement and modification of hepatic microsomal drug metabolism in rats by pyrethrum. PMID- 4144494 TI - [The effect of obstetric anesthesia on the uterine activity]. PMID- 4144495 TI - [Associated ventricular tachycardia and auricular fibrillation after anticholera vaccination]. PMID- 4144496 TI - Dysrhythmias during inhalational anaesthesia for oral surgery. Incidence and prevention and treatment with practolol. PMID- 4144497 TI - Comparative inhibition studies of the phosphotransferase and glycerophosphate acylation systems in membrane vesicles of Escherichia coli. PMID- 4144498 TI - Anaesthesia for liver transplantation in primates. PMID- 4144499 TI - Beta-blockade and left ventricular performance under halothane anesthesia. PMID- 4144501 TI - [Loss of teeth and dental caries in man. Statistics of 3576 clinically examined subjects]. PMID- 4144500 TI - Combination chemotherapy for clinically established graft-versus-host disease in mice. PMID- 4144502 TI - [Local application of fluorine protective varnish for caries prevention in collectivities]. PMID- 4144503 TI - Histochemistry of succinate dehydrogenase, glucose-6-phosphate dehydrogenase and NADPH tetrazolium reductase in human skin. I. Post-mortem variations and effects of autolysis, and histotopography. PMID- 4144504 TI - Histochemistry of succinate dehydrogenase, glucose-6-phosphate dehydrogenase and NADPH tetrazolium reductase in human skin. II. Regional differences in histochemical activity. PMID- 4144505 TI - [Psychopharmacological therapy of psychoses. 5. Thymoneuroleptic agents]. PMID- 4144506 TI - Biochemical cytology of trichomonad flagellates. I. Subcellular localization of hydrolases, dehydrogenases, and catalase in Tritrichomonas foetus. AB - To determine the localization of several enzymes in Tritrichomonas foetus, the axenic KV-1 strain was grown in Diamond's medium with bovine serum, homogenized in 0.25 M sucrose, and subjected to analytical differential and isopycnic centrifugation. The fractions were assayed for their enzymatic composition and examined electron microscopically. NADH and NADPH dehydrogenases, about 90% of the catalase, and two hydrolases, alpha-galactosidase and manganese-activated beta-galactosidase I are in the nonsedimentable part of the cytoplasm. alpha Glycerophosphate and malate dehydrogenases are associated with a large particle, whose equilibrium density in sucrose gradients is 1.24. This particle corresponds to that population of the paracostal and paraxostylar granules which, having a uniform granular matrix surrounded by a single membrane, resemble microbodies from other organisms. The small sedimentable portion of catalase (about 10% of the total activity) is not associated with these granules and equilibrates at density 1.22. The nature of the subcellular entity carrying catalase could not be ascertained. Hydrolases with a pH optimum around 6-6.5 (protease, beta-N acetylglucosaminidase, beta-N-acetylgalactosaminidase, and cation-independent beta-galactosidase II), as well as a large part of acid phosphatase, are associated with a population of large particles which equilibrate at densities from 1.15 to 1.20. The hydrolases in these granules lose their structure-bound latency easily after freezing and thawing. These particles correspond to another population of the paracostal and paraxostylar granules which have varied shape and inhomogeneous content with frequent myelin figures, indicating a digestive function. The rest of the phosphatase and most of the acid beta-glucuronidase activity are in a smaller granule fraction with an equilibrium density around 1.18. The latency of these enzymes is quite resistant to freezing and thawing. This particle population consists of smaller, very often flattened vesicles and granules, many of which are clearly fragments of the prominent Golgi apparatus of the cell. PMID- 4144507 TI - Intravenous infusion of salbutamol in the management of premature labour. PMID- 4144508 TI - [Let your horizons be broad]. PMID- 4144509 TI - [International Congress of Midwives in Washington, D.C]. PMID- 4144511 TI - [Years as assistant and associate professor in Graz (1923-1930). The E.N.T. Clinic, medical school and scientific societies with their members. I]. PMID- 4144510 TI - Pharmacological studies of two new cardioselective adrenergic beta-receptor antagonists. PMID- 4144512 TI - [Sport accidents in ice hockey]. PMID- 4144514 TI - [Althaea, ipecac, senega and thyme as cough medicines]. PMID- 4144513 TI - Isolated hormone receptors: physiologic and clinical implications. PMID- 4144516 TI - Thermal properties of the collagen of jellyfish (Aurella coerulea) and their relation to its thermal behaviour. PMID- 4144515 TI - [Experimental findings concerning treatment of anabasine sulfate poisoning]. PMID- 4144517 TI - Influence of electron transport on the interaction between membrane lipids and Triton X-100 in Halobacterium cutirubrum. PMID- 4144518 TI - [Etiology and therapy of the most common congenital malformations--reply to the paper by H. Eimer]. PMID- 4144519 TI - Introduction to IUPS Satellite Symposium (Gyllenberg-Symposium), Helsinki, Finland, August 2-3, 1971. 'Information transfer from a neurophysiological and neurochemical point of view'. PMID- 4144521 TI - A mosquito parasite from a mosquito predator. PMID- 4144522 TI - A canonical-correlation analysis of 16 fear factors and the MMPI. PMID- 4144520 TI - Changes in the constitutive enzymes of chick cells following infection with Semliki Forest virus. PMID- 4144523 TI - [The relationship between anesthesia and the mineralocorticoid function of the adrenals during surgery]. PMID- 4144525 TI - Polyarteritis. PMID- 4144526 TI - Brain amine and adrenal enzyme levels in aggressive, bulbectomized rats. PMID- 4144524 TI - [Psychopharmacological agents in children]. PMID- 4144527 TI - Carbohydrate transport by micro-organisms. PMID- 4144528 TI - The role of lymphocytes in antibody formation. V. Transfer of immunological memory to tetanus toxoid: the origin of plasma cells from small lymphocytes, stimulation of memory cells in vitro and the persistence of memory after cell transfer. PMID- 4144529 TI - Two models of the partially focused clear zone compound eye. PMID- 4144530 TI - The dioptric system of the eye of Cybister (Dytiscidae: Coleoptera). PMID- 4144531 TI - MMPI personality patterns of alcoholics and narcotic addicts. PMID- 4144532 TI - Wives of alcoholics. A critical review and analysis. PMID- 4144533 TI - The prophylactic effect of salazosulphapyridine in ulcerative colitis during long term treatment. A double-blind trial on patients asymptomatic for one year. PMID- 4144534 TI - [Enzymes of glutamine metabolism in the brain in acute hypoxic hypoxia]. PMID- 4144535 TI - Relationship between cyclic AMP, phosphodiesterase activity, calcium and contraction in intestinal smooth muscle. PMID- 4144536 TI - Interaction between the fastigial pressor response and the defence reaction. PMID- 4144537 TI - [Histoenzymological study of Klinefelter's testis]. PMID- 4144538 TI - Alcohol dehydrogenase activity in Rhodotorula glutinis. PMID- 4144539 TI - [Polyarteriitis nodosa in an infant]. PMID- 4144540 TI - Chemical facilitation in dynamic models of neural macrostates. PMID- 4144541 TI - Effects of an hyperoxic hypobaric environment on renin-aldosterone in normal man. PMID- 4144542 TI - Adenylate cyclase in islets of Langerhans. Isolation of islets and regulation of adenylate cyclase activity by various hormones and agents. PMID- 4144543 TI - Biosynthesis of prelycopersene pyrophosphate and lycopersene by squalene synthetase. PMID- 4144544 TI - Prelycopersene pyrophosphate and lycopersene. Intermediates in carotene biosynthesis. PMID- 4144545 TI - Enzymatic oxidation of nicotine to nicotine 1'(5') iminium ion. A newly discovered intermediate in the metabolism of nicotine. PMID- 4144546 TI - Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. II. Identification of a new class of heme prosthetic group: an iron-tetrahydroporphyrin (isobacteriochlorin type) with eight carboxylic acid groups. PMID- 4144547 TI - Characterization of an adrenal activator for cholesterol side chain cleavage. PMID- 4144548 TI - Lumisomes, the cellular site of bioluminescence in coelenterates. PMID- 4144549 TI - A comparative study of growth and development in Florida mosquitoes. 4. Effects of temporary crowding during larval stages on female flight activity patterns. PMID- 4144550 TI - Factors affecting mass production of Reesimermis nielseni, a nematode parasite of mosquitoes. PMID- 4144551 TI - The mosquito fauna of Sinai. PMID- 4144552 TI - Drug-induced extrapyramidal symptoms. A cooperative study. PMID- 4144553 TI - Medical aspects of diving. 2. PMID- 4144555 TI - Evidence from electron microscope studies on actin paracrystals concerning the origin of the cross-striation in the thin filaments of vertebrate skeletal muscle. PMID- 4144554 TI - [Calcium metabolism during antiepileptic therapy]. PMID- 4144556 TI - The influx of amino acids into the brain of the rat in vivo: the essential compared with some non-essential amino acids. PMID- 4144557 TI - The transport of glucose into the brain of the rat in vivo. PMID- 4144558 TI - A note suggesting that the cross-bridge attachment during muscle contraction may take place in two stages. PMID- 4144559 TI - Instructions, word association, and the hospitalized psychiatric patient. PMID- 4144560 TI - [Clinical forms of mastocytosis]. PMID- 4144561 TI - [Controlled hypotension in oral and otorhinolaryngologic operations under anesthesia]. PMID- 4144563 TI - [Recommendations of the fourth meeting of the FAO-OIE-OUA expert panel on contagious bovine pleuropneumonia. Held in Paris, France, 15-20 March, 1971]. PMID- 4144562 TI - [Effect of -receptor blockaders on "experimental sialadenosis"]. PMID- 4144564 TI - Meeting of the sub-committee of the FAO-OIE-OAU expert panel on contagious bovine pleuropneumonia. PMID- 4144565 TI - Cyclic AMP and intestinal glycoprotein synthesis: the effect of -adrenergic agents, theophylline, and dibutyryl cyclic AMP. PMID- 4144566 TI - Evaluation of a new B 2 adrenergic receptor stimulant, terbutaline, in bronchial asthma. I. Subcutaneous comparison with epinephrine. PMID- 4144567 TI - Evaluation of a new B 2 adrenergic receptor stimulant, terbutaline, in bronchial asthma. II. Oral comparison with ephedrine. PMID- 4144568 TI - A comparative analysis of the ontogenic development of rat liver sequential enzymes-tyrosine -ketoglutarate aminotransferase, p-hydroxyphenylpyruvate hydroxylase, and homogenitsate oxygenase. PMID- 4144569 TI - Drug addiction and the newborn. PMID- 4144570 TI - [Clinical and biochemical studies on the utilization of adrenergic beta blockaders in the induction and stimulation of labor]. PMID- 4144571 TI - Energetics of growth in a tyrothricin-producing strain of Bacillus brevis. PMID- 4144572 TI - Antigen-induced depression of DNA synthesis in mouse spleen. PMID- 4144573 TI - Hydroxylation and biogenic amine synthesis in the human fetus. PMID- 4144574 TI - Development of adrenergic neurons in vivo: inhibition by ganglionic blockade. PMID- 4144575 TI - Tyrosine hydroxylase activity in rat brain following "REM" sleep deprivation. PMID- 4144576 TI - [Testicular tumors]. PMID- 4144577 TI - The multimeric nature of NADPH-nitrate reductase from Aspergillus nidulans. PMID- 4144578 TI - Stimulants for insomnia. PMID- 4144579 TI - [Oligo- and polypeptide antibiotics]. PMID- 4144580 TI - Progress in anxiety states. PMID- 4144581 TI - Effects of halothane on the cyclic 3',5'-adenosine monophosphate (cyclic AMP) system in rat uterine muscle. PMID- 4144582 TI - Partial hypogonadotrophic hypogonadism: studies of pituitary function and of the pituitary-testicular relationship in two patients. PMID- 4144583 TI - Uptake and release of -aminobutyric acid (GABA) in slices of substantia nigra of rat. PMID- 4144584 TI - Kinetic and enzymatic features of metabolic stimulation of alveolar and peritoneal macrophages challenged with bacteria. PMID- 4144585 TI - Comparison of new -andrenergic blockers, C-3, Ko1366, Y-6124 and YB-2, with pindolol and propranolol in the blood perfused canine papillary muscle preparation. PMID- 4144586 TI - 10-Methoxyergoline derivatives as -adrenergic blocking agents. PMID- 4144587 TI - Comparison of -adrenergic blocking activity of eight blockers in the excised and blood-perfused canine sino-atrial node preparation. PMID- 4144588 TI - Genetic analysis of ribonucleic acid polymerase mutants of Bacillus subtilis. AB - Deoxyribonucleic acid-dependent ribonucleic acid polymerase mutants of Bacillus subtilis strain Marburg were isolated after mutagenesis of spores with ethyl methane sulfonate. Genetic analysis by PBS1-mediated transduction and by transformation indicated that mutations responsible for all of the four phenotypic classes studied (rifampin resistance, streptovaricin resistance, streptolydigin resistance, and temperature sensitivity) were clustered close to the cysA14 locus. Three-factor transformation analysis has indicated the most probable marker order as follows: Rif(R)(Stv)(R)-Std(R)-Ts(418)-Ts(427). In addition, further characterization of the classical group I reference marker, cysA14, is reported. PMID- 4144589 TI - Competence for deoxyribonucleic acid uptake and deoxyribonuclease action external to cells in the genetic transformation of Diplococcus pneumoniae. AB - A mutant of Diplococcus pneumoniae that apparently does not require activator can become competent for uptake of deoxyribonucleic acid (DNA) when grown in dilute cultures or in the presence of trypsin. Development of competence in both mutant and wild strains is temperature dependent, being 10-fold greater at 30 C than at 37 C. Induction of competence on a shift from 37 to 30 C requires protein synthesis and the presence of Mg(2+) and Ca(2+); uptake of DNA does not require protein synthesis. Competence decays exponentially at higher temperatures. As well as taking up DNA, competent cells release oligonucleotide fragments of donor DNA in the medium external to the cells. Normal strains release fragments comparable in amount to the DNA taken up; but, in a mutant selected for inability to degrade DNA in agar, the amount of fragments formed external to the cells is only 40% of DNA uptake. Requirements for external deoxyribonuclease action are identical to those for DNA uptake: prior development of competence and the presence during treatment with DNA of Mg(2+) ions and a source of energy. PMID- 4144590 TI - Pyridine nucleotide-dependent glucose dehydrogenase activity in blue-green algae. AB - Pyridine nucleotide-dependent glucose dehydrogenase activity (GPND) is described for the first time in cell-free extracts of certain blue-green algae. When glucose is added to these crude cell extracts, nicotinamide adenine dinucleotide phosphate is reduced at twice the rate as nicotinamide adenine dinucleotide; but evidence suggests that this activity is due to a single enzyme. The distribution and level of GPND in selected blue-green algae correlates with the heterotrophic potential of each species. In all blue-green algae where GPND was detected, O(2) uptake coupled to the GPND reaction was also observed. Both GPND and O(2) uptake apparently occur in the soluble fraction of the cell. An essential role for GPND in the heterotrophic metabolism of blue-green algae is postulated. PMID- 4144591 TI - Rat brain tyrosine hydroxylase. Activation by limited tryptic proteolysis. PMID- 4144592 TI - Partial resolution of the enzymes catalyzing oxidative phosphorylation. 28. The reconstitution of the first site of energy conservation. PMID- 4144593 TI - Catecholamine metabolism in tissue culture cells of a neuroblastoma. PMID- 4144594 TI - Subcellular distribution of isocitrate dehydrogenases in neonatal and adult mouse brain. PMID- 4144596 TI - Isoenzymes of -glutamyl transpeptidase in liver diseases. PMID- 4144597 TI - Nocardia--streptomyces infection of the foot. PMID- 4144598 TI - [Drug monitoring in the medical ward of a regional hospital]. PMID- 4144599 TI - Reflex responses to stimulation of the upper respiratory tract. PMID- 4144595 TI - Immunosuppression and neoplasia. II. Is deficient immunesurveillance the only mechanism by which immunosuppression promotes neoplasia? A speculative review. PMID- 4144601 TI - [Glucose-6-phosphate dehydrogenase inhibition by steroids. 5. Influence of placental glucose-6-phosphate dehydrogenase activity on 7 - 3 H dehydroepiandrosterone metabolism]. PMID- 4144600 TI - Cell-mediated immunity after thermal injury. PMID- 4144602 TI - Man and his environment. PMID- 4144603 TI - A vasectomy prosthesis. PMID- 4144604 TI - Perforation of the colon in the neonate. PMID- 4144605 TI - Pituitary apoplexy. PMID- 4144606 TI - Concepts of management in infertility. PMID- 4144607 TI - Traumatic visceral pseudoaneurysms. PMID- 4144608 TI - Pneumococcal arthritis: report of a case and review of the literature. PMID- 4144609 TI - [Immunologic problems in bone marrow transplantation]. PMID- 4144610 TI - [Immunology of cancer]. PMID- 4144611 TI - [Treatment of degenerative colonic and rectal adenomas]. PMID- 4144612 TI - [Pathologicoanatomical aspects of tumors with endocrine activity]. PMID- 4144613 TI - [Shock treatment in the severely injured]. PMID- 4144615 TI - Immunologic studies on resistance to oncogenic agents in mice. PMID- 4144614 TI - [Induction and maintenance of immunological transplant tolerance in the adult organism]. PMID- 4144616 TI - Amino-acid sequence homologies between the NADP-dependent glutamate dehydrogenase of Neurospora and the bovine enzyme. PMID- 4144618 TI - Polyarteritis nodosa and pregnancy: report of a successful outcome. PMID- 4144617 TI - Extracorporeal animal liver perfusion in patients in hepatic coma: anesthesiological problems. PMID- 4144619 TI - Eosinophilic lung disease (or how to slice P.I.E.). PMID- 4144620 TI - An isotopic assay of cyclic 3',5'-nucleotide phosphodiesterase with aluminum oxide columns. PMID- 4144621 TI - A microwell assay method for the biochemical study of cultured cells. PMID- 4144622 TI - Amylase and acid phosphatase in unstimulated human parotid fluid. PMID- 4144623 TI - Tolerance and side effects during long term treatment of hypertension with debrisoquine. PMID- 4144624 TI - Phenothiazines and jaundice. PMID- 4144625 TI - Phaeochromocytoma with catecholamine cardiomyopathy successfully treated surgically. PMID- 4144626 TI - Histochemical demonstration of enzymes in the uropygial gland of the fowl. PMID- 4144627 TI - The influence of lipophilicity on the antibacterial activity of rifamycins. PMID- 4144628 TI - An attempt to identify putative neurotransmitter molecules in the central nervous system of the snail. PMID- 4144629 TI - [Radio-sensitization of DNA to denaturation; influence of the irradiation conditions]. PMID- 4144631 TI - The homeostatic nursing care plan. PMID- 4144630 TI - Endoplasmic reticulum as the site of lecithin formation in castor bean endosperm. AB - The properties of a discrete membranous fraction isolated on sucrose gradients from castor bean endosperm have been examined. This fraction was previously shown to be the exclusive site of phosphorylcholine-glyceride transferase. The distribution of NADPH-cytochrome c reductase and antimycin insensitive NADH cytochrome c reductase across the gradient followed closely that of the phosphorylcholine-glyceride transferase. This fraction also had NADH diaphorase activity and contained cytochromes b(5) and P 450. On sucrose gradients containing 1 mM EDTA this fraction had a mean isopycnic density of 1.12 g/cm(3) and sedimented separately from the ribosomes; electron micrographs showed that it was comprised of smooth membranes. When magnesium was included in the gradients to prevent the dissociation of membrane-bound ribosomes, the isopycnic density of the membrane fraction with its associated enzymes was increased to 1.16 g/cm(3) and under these conditions the electron micrographs showed that the membranes had the typical appearance of rough endoplasmic reticulum. Together these data show that the endoplasmic reticulum is the exclusive site of lecithin formation in the castor bean endosperm and establish a central role for this cytoplasmic component in the biogenesis of cell membranes. PMID- 4144632 TI - The use of simulation with students having a community health nursing experience. PMID- 4144633 TI - The beginnings of nursing education in the United States: an analysis of the times. PMID- 4144634 TI - Competencies of nursing directors in junior colleges. PMID- 4144635 TI - Small interactional groups in the psychiatric training of graduate nursing students. PMID- 4144636 TI - Opsonins: their function, identity, and clinical significance. PMID- 4144637 TI - Effects of antihistamine-epinephrine combinations on adjuvant arthritis in rats. PMID- 4144639 TI - [Prognosis of skin tumors]. PMID- 4144638 TI - Dimethylformamide dimethylacetal as a derivatizing agent for GLC of barbiturates and related compounds. PMID- 4144640 TI - [Neoplasm morbidity in pernicious anemia]. PMID- 4144641 TI - [Differential diagnosis of the so-called neuroses]. PMID- 4144643 TI - [Diagnosis and prognosis of eye injuris]. PMID- 4144642 TI - [Clinical pharmacodynamic effects of delta-9-tetrahydrocannabinol]. PMID- 4144644 TI - [Expert testimony on an unusual eye injruy]. PMID- 4144645 TI - [Studies during the interval of phasic psychoses]. PMID- 4144646 TI - [New antihypertensive drugs]. PMID- 4144647 TI - [Influence of trimepranol on somatotropin, insulin, glucose and on serum free fatty acids in thyrotoxicosis]. PMID- 4144648 TI - [A case of a rarely encountered form of periarteritis nodosa]. PMID- 4144649 TI - [Bituminosulfate and composition of skin surface lipids in acne vulgaris]. PMID- 4144650 TI - Urinary steroid patterns after short and long term treatment with human chorionic gonadotropin (HCG) of prepubertal boys with undescended testes. PMID- 4144651 TI - Burned feet in children. Acute and reconstructive care. PMID- 4144652 TI - Effect of osmotic stabilizers on 14 CO 2 production by bacteria and blood. AB - Evolution of (14)CO(2) by whole blood as well as by Diplococcus pneumoniae, Haemophilus sp., Pseudomonas aeruginosa, Pseudomonas diminuta, and Streptococcus pyogenes was examined by using the BACTEC system. The control medium was JLI no. 6A culture vial containing 30 ml of enriched tryptic soy broth and 1.5 muCi of (14)C-substrate. Hypertonic media consisted of control medium with either 1 or 3% NaCl, 10% sucrose, and 5%, 10%, or 15% dextran. The most deleterious treatment to bacteria was 3% NaCl since it not only retarded (14)CO(2) production, but also prevented growth of D. pneumoniae, Haemophilus, and P. diminuta. The 10% sucrose treatment diminished (14)CO(2) output, although it did not retard growth of test organisms. This effect was probably due to (14)C-substrate dilution rather than to osmotic effects. Dextran had slight effect on (14)CO(2) production and slightly acidified the medium. Of the treatments tested, only 10% sucrose reduced normal output of (14)CO(2) by whole blood. This also is probably due to (14)C substrate dilution. It appears that 10% sucrose is potentially the most useful osmotic agent for radiometric techniques since, although bacterial (14)CO(2) production is lowered, blood (14)CO(2) is lowered also. PMID- 4144653 TI - Use of technetium ( 99m Tc) as a bacterial label in lung clearance studies. AB - The suitability of technetium ((99m)Tc), a gamma emitter, for labeling of Diplococcus pneumoniae in studies of lung bacterial clearance was examined. A killed bacterial slurry with high specific activity was obtained with a ferric ascorbate reducing system. Approximately 5.5% of radioactive counts dissociated from labeled bacteria in 6 h. Rats were exposed to a uniformly mixed aerosol of untagged, viable pneumococci and killed, (99m)Tc-tagged pneumococci. The aerodynamic behavior of labeled and unlabeled pneumococci was similar. Viable bacterial counts and radioactive counts were determined in lung homogenates at intervals following exposure, and rates of bacterial killing and disappearance of radioactive counts were plotted. Radioactive counts did not increase in the liver during the period of observation, suggesting that the decrease in lung radioactivity represents mucociliary clearance and not release of isotope to the systemic circulation. The use of (99m)Tc for bacterial labeling provides advantages of technical simplicity and personnel safety compared to the use of beta-emitting isotopes. PMID- 4144654 TI - Properties of homoserine dehydrogenase in a thermophilic bacterium. PMID- 4144655 TI - Studies of a halophilic NADH dehydrogenase. I. Purification and properties of the enzyme. PMID- 4144656 TI - Activation of guanyl cyclase and adenyl cyclase by secretin. PMID- 4144657 TI - [Oral hygiene and periodontal diseases and dental caries]. PMID- 4144658 TI - [Prescription of an emetic drug as first aid in acute poisoning]. PMID- 4144659 TI - Introductory address presented at the Sixth Conference of European Comparative Endocrinologists, Montpellier, 1971. General aspects and problems in comparative endocrinology. PMID- 4144660 TI - Histological and histochemical findings in muscle spindles in dystrophia myotonica. PMID- 4144661 TI - Structural changes in myosin in dystrophic, denervated and regenerating muscle in mice. PMID- 4144662 TI - Prevalence of rheumatic disease. PMID- 4144663 TI - Necrotizing arteritis and other forms of vasculitis. PMID- 4144664 TI - [Recurrent purulent meningitis, apropos of 2 cases]. PMID- 4144665 TI - Basal level of neurotransmitter synthesizing enzymes and effect of cyclic AMP agents on the morphological differentiation of isolated neuroblastoma clones. PMID- 4144666 TI - Haemolytic phospholipase A and nerve-affecting activities of sea anemone nematocyst venom. PMID- 4144667 TI - Effect of tyrosine hydroxylase inhibition on the action of 6-hydroxydopamine. PMID- 4144668 TI - Bacterial endocarditis in x-irradiated rats: effect of isoproterenol and adrenergic receptor blocking agents. PMID- 4144669 TI - [Effect of adrenergic substances on the acid and alkaline secretion of the stomach]. PMID- 4144670 TI - Pathogenesis of the graft-versus-host reaction in chicken embryos. The development of haemorrhagic lesions. PMID- 4144671 TI - Enzymatic histone modification during the induction of tyrosine aminotransferase with insulin and hydrocortisone. PMID- 4144672 TI - Duration of action of beta-blocking drugs. PMID- 4144673 TI - Suicide attempt with practolol. PMID- 4144674 TI - Serum gamma glutamyl transpeptidase in liver disorders. PMID- 4144675 TI - A contribution to the mechanism of drug inhibition of the graft vs host reaction. PMID- 4144676 TI - Effect of prostaglandin E 1 on cellular and humoral immune responses. PMID- 4144677 TI - Noonan's syndrome and cryptorchidism. PMID- 4144678 TI - Excretory urography in asymptomatic boys with cryptorchidism. PMID- 4144679 TI - Action of acetylcholine on the longitudinal muscle of guinea-pig ileum: the role of an electrogenic sodium pump. PMID- 4144680 TI - The action of catecholamines on guinea-pig taenia coli. PMID- 4144681 TI - The nervous release and the action of substances which affect intestinal muscle through neither adrenoreceptors nor cholinoreceptors. PMID- 4144682 TI - Adrenergic influences on uterine smooth muscle. PMID- 4144683 TI - The stimulant action of acetylcholine and catecholamines on the uterus. PMID- 4144684 TI - A discussion on recent developments in vertebrate smooth muscle physiology. A survey of new findings and the discussions arising during sessions I. II and 3. PMID- 4144685 TI - The mechanism of contraction. PMID- 4144686 TI - Sarcoplasmic reticulum and mitochondria as cation accumulation sites in smooth muscle. PMID- 4144687 TI - The subunit structure of gizzard myosin. PMID- 4144688 TI - The structure of the myosin elements in vertebrate smooth muscles. PMID- 4144689 TI - The influence of temperature on the thick filaments of vertebrate smooth muscle. PMID- 4144690 TI - The assembly of ribbon-shaped structures in low ionic strength extracts obtained from vertebrate smooth muscle. PMID- 4144691 TI - Smooth muscle: contraction hypothesis based on the arrangement of actin and myosin filaments in different states of contraction. PMID- 4144692 TI - The site and state of myosin in intestinal smooth muscle. PMID- 4144693 TI - Filament organization in vertebrate smooth muscle. PMID- 4144694 TI - A discussion on recent developments in vertebrate smooth muscle physiology: concluding remarks. PMID- 4144695 TI - Structure and electrical properties of the autonomic neuromuscular junction. PMID- 4144696 TI - Ion distribution and the role of calcium in cellular function. Ion distribution and ion movements in smooth muscle. PMID- 4144697 TI - Smooth muscle physiology, past and future. PMID- 4144698 TI - Active ion transport and resting potential in smooth muscle cells. PMID- 4144699 TI - Factors controlling cytoplasmic Ca 2+ concentration. PMID- 4144700 TI - Factors controlling myogenic activity in smooth muscle. PMID- 4144701 TI - Cellular structures and electrophysiological behaviour. Fine structure of smooth muscle. PMID- 4144702 TI - Na-Ca exchange and tension development in arterial smooth muscle. PMID- 4144703 TI - The mechanisms of action of neurotransmitters. Electrical changes underlying excitation and inhibition in intestinal and related smooth muscle. PMID- 4144704 TI - [Critical evaluation of the serum enzymatic diagnosis of liver diseases]. PMID- 4144705 TI - [Histological and histochemical artifacts in peroperative hepatic biopsy]. PMID- 4144706 TI - Effect of iron and calcium on salicylazosulphapyridine metabolism. PMID- 4144707 TI - Profound sensorineural hearing loss associated with collagen disease. PMID- 4144708 TI - [Developmental status and perspectives of psychology in the USSR from the viewpoint of the resolutions of the XXIV party meeting of the Communist Party of the Soviet Union]. PMID- 4144709 TI - [Diagnosis of neurologic and psychiatric diseases by experimental psychological test data using discriminance analysis]. PMID- 4144710 TI - [Neuropsychological methods for the analysis of functions and components of linguistic functional partial systems]. PMID- 4144711 TI - Piperacetazine and chlorpromazine: a comparison. PMID- 4144712 TI - [Nosological and evolutive aspects of periarteritis nodosa (apropos of 25 cases)]. PMID- 4144713 TI - -adrenergic blocking and cardiovascular properties of a new compound, 1-(7 indenyloxy)-3-isopropylaminopropan-2-ol-hydrochloride (YB-2). PMID- 4144714 TI - Some pharmacological effects of centrophenoxine and its components in mice. PMID- 4144715 TI - [Studies on the antiallergic and corticosecretory effects of 8-phenethyl-1-oxa 3,8-diaza-spiro(4,5)decan-2-one (fenspiride, JP 428)]. PMID- 4144716 TI - The management of depression in consultant medical practice. PMID- 4144717 TI - Studies on the inhibition of glutamine synthetase by methionine sulfone. PMID- 4144718 TI - Inhibition by serotonin of glutamine synthetase formation in cultured mouse cells strain L. PMID- 4144719 TI - Beta-blockade of epinephrine-induced cyclic AMP formation in heart, liver, fat and trachea. PMID- 4144720 TI - Control of cyclic AMP levels in isolated fat cells from hamsters. PMID- 4144721 TI - Bacterial resistance: changing patterns of some common pathogens. PMID- 4144722 TI - Haematology and biochemistry of ankylosing spondylitis. AB - Forty men with ankylosing spondylitis have been reviewed clinically, radiologically, haematologically, and biochemically, and the results of the last two compared with a male group of rheumatoid patients and a control group. In the patients with ankylosing spondylitis the haemoglobin levels were much higher and the E.S.R. significantly lower than in the rheumatoid group, and the E.S.R. in the patients with ankylosing spondylitis was unrelated to disease activity as evidenced by pain. The alkaline phosphatase level was raised in 19 cases and in most was derived from bone. Though 10 patients had abnormal globulin levels, the albumin levels were normal, as was renal function in all cases. PMID- 4144723 TI - A device for the self-marking of mosquitos. AB - The authors describe a simple device for marking emergent adult mosquitos with fluorescent dye. This technique is of value in the study of the dynamics of insect populations. PMID- 4144724 TI - Properties of hepatic hexose-6-phosphate dehydrogenase purified from brook trout and lake trout. PMID- 4144725 TI - Enzymatic activities of venom from the jellyfish Stomolophus meleagris. PMID- 4144726 TI - [Dynamics of loss of permanent teeth in school children]. PMID- 4144727 TI - Regulation of gene function: a comparison of X-linked enzyme activity levels in normal and intersexual triploids of Drosophila melanogaster. AB - We have measured gene function in normal and male-like intersexual triploids of Drosophila melanogaster by assaying crude extracts of whole flies or thoraces for levels of an X-linked (6-phosphogluconate dehydrogenase) and an autosomal (NADP dependent isocitrate dehydrogenase) enzyme activity. Our observations lead us to conclude that each dose of the X-linked gene is more active in the cells of these intersexes than it is in normal triploid or diploid female cells. These results indicate that a level of activity intermediate between the normal male and female levels is possible for X-linked genes. PMID- 4144728 TI - When postural hypotension signals disease. PMID- 4144729 TI - [Relationship between the pressure gradient and the decrease of blood pressure in acute experimental stenosis of the mesenteric arteries]. PMID- 4144730 TI - Psychological adjustment--mood and personality fluctuations of long-term methadone maintenance patients. PMID- 4144731 TI - [Current drugs. Therapy using -blockaders ( -adrenolytics)]. PMID- 4144732 TI - Dihydrofolate reductase and aminopterin resistance in Pneumococcus. PMID- 4144733 TI - [A new screening test in onchology. Gamma-glutamyl transpeptidase in the diagnosis of hepatic metastases]. PMID- 4144734 TI - [Indications for bone marrow transplantation in aplastic anemia and acute myeloid leukemia]. PMID- 4144735 TI - Surgery of the male genital tract in cattle: a review of 121 cases. PMID- 4144736 TI - A simple radioisotope assay for microsomal aryl hydroxylase. PMID- 4144737 TI - The preparation of stereospecific tritium-labeled reduced nicotinamide adenine dinucleotide phosphate. PMID- 4144738 TI - Differences in the redox balance in human rheumatoid and non-rheumatoid synovial lining cells. PMID- 4144739 TI - The effects of early experimental cryptorchidism and subsequent orchidopexy on the maturation of the guinea-pig testicle. PMID- 4144740 TI - The effect of unilateral experimental cryptorchidism and subsequent orchidopexy upon maturation of the contralateral scrotal testicle of the guinea-pig. PMID- 4144741 TI - Structural features inhibiting the cross-reaction of the acidic polysaccharide from Tremella mesenterica with a type II anti-pneumococcal serum. PMID- 4144742 TI - Fatty acid synthetase from Pythium debaryanum. PMID- 4144743 TI - Purification and some properties of the glutamate dehydrogenase of Salmonella typhimurium. PMID- 4144744 TI - Studies on the kinetics and regulation of glutamate dehydrogenase of Salmonella typhimurium. PMID- 4144745 TI - Isocitrate supported nitrogenase activity in Gloeocapsa sp. LB 795. PMID- 4144746 TI - Studies on isocitrate lyase from the facultative autotroph Thiobacillus novellus. PMID- 4144747 TI - The development of the immune response to type 3 pneumococcal polysaccharide in chickens. PMID- 4144748 TI - A study of the role of allocluster-forming cells in the graft-versus-host reaction in chickens. PMID- 4144749 TI - [Effect of beta receptor blockaders in orthostatic dysregulation in a critical study and following long-term therapy]. PMID- 4144750 TI - Gastric and intestinal transit in rats measured by a radioactive test meal. PMID- 4144751 TI - Symposium on gastrooesophageal reflux and its complications. 4. Pharmacology and therapeutics. PMID- 4144752 TI - The regulation of rat liver calciferol-25-hydroxylase. PMID- 4144753 TI - Resistance of microsomes from CCl 4 -ccirrhotic rat liver to lipoperoxidation activity. PMID- 4144754 TI - Post-transcriptional inhibition of protein synthesis by rifampicin in rat hepatoma cells. PMID- 4144755 TI - The intermediate coronary syndrome: clinical, angiographic and therapeutic aspects. PMID- 4144756 TI - Drug therapy. Anticholinergics. PMID- 4144757 TI - [Clinical value of gamma-glutamyl-transpeptidase]. PMID- 4144758 TI - [Activity of gamma-glutamyl-transpeptidase in myocardial infarct]. PMID- 4144759 TI - Circadian rhythms in neurospora: spatial differences in pyridine nucleotide levels. AB - A growing colony of a mutant strain of Neurospora crassa had two morphologically distinct areas which were formed as a result of a rhythmic spore-forming (conidiation) process. The total pyridine nucleotide content of these two areas was the same, but the levels of NADH, NADPH, and NADP were lower in the conidiating area, while the NAD level was higher. These biochemical differences in the adjacent areas of a single colony were only found in newly formed areas, and were not a permanent record. It is not known whether these pyridine nucleotide changes are a result of the conidiation process, or whether they are tied more directly to some underlying metabolic oscillation. However, it is speculated that the changes in the levels of these key coenzymes could have far reaching effects on many areas of metabolism. PMID- 4144760 TI - The effect of some cytostatics on tyrosine aminotransferase activity in rat liver. PMID- 4144761 TI - Experimental metastasizing in syngeneic and autochthonous tumour-host systems. PMID- 4144762 TI - An ultrastructural comparison of peripheral nerve allografts and autografts. PMID- 4144763 TI - Adrenergic mechanisms in the canine ureter. PMID- 4144765 TI - Norepinephrine-responsive beta-adrenergic receptors in rabbit lacrimal gland. PMID- 4144764 TI - Evidence for nonadrenergic inhibitory nerves in the guinea pig trachealis muscle. PMID- 4144766 TI - Stimulation of pentose cycle in the eccrine sweat gland by adrenergic drugs. PMID- 4144767 TI - The development of health services for mothers and children in the United States. PMID- 4144768 TI - [Modification of enzyme induction as the early effect of carcinogenic substances]. PMID- 4144770 TI - Temporal changes in amine synthesizing enzymes of rat extrapyramidal structures after hemitransections or 6-hydroxydopamine administration. PMID- 4144769 TI - The in vitro activity of peritoneal exudate cells of NZB-B1 and BALB-C mice following intraperitoneal injection of spleen cells from diseased and "healthy" NZB-B1 and from old and young BALB-C mice. PMID- 4144771 TI - [Dental survey of a standard population in the Sternberg region. IV. Partial and total tooth loss-objectification of partial and total dentures]. PMID- 4144772 TI - Peroxisomal enzymes in human granulocytes. II. D-aminoacid oxidases and L- hydroxyacid oxidases. PMID- 4144773 TI - [Effects of 1-(7-indenyloxy)-3-isopropylaminopropan-2-ol hydrochloride (YB-2) on coronary circulation and and myocardial metabolism]. PMID- 4144774 TI - Central nervous actions and screening methods of antidepressants. PMID- 4144775 TI - Impaired folic acid absorption in inflammatory bowel disease: effects of salicylazosulfapyridine (Azulfidine). PMID- 4144776 TI - Colonic complications after renal transplantation. PMID- 4144777 TI - Dental caries in 506 young Ontario adults. PMID- 4144778 TI - Aminopeptidases of rat testis. II. Effects of puberty, cryptorchidism and cadmium chloride treatment. PMID- 4144779 TI - Aminopeptidases of rat testis. 3. Activity of dipeptidyl aminopeptidases I and II in normal and experimental conditions. PMID- 4144780 TI - Extrapulmonary manifestations of respiratory disease with emphasis on abnormal electron (redox) metabolism. PMID- 4144781 TI - Therapy of bronchial asthma. PMID- 4144782 TI - [Histochemical determination of early myocardial infarction]. PMID- 4144783 TI - [Ethaverin, a coronary dilator with beta-receptor depressing and antiarrhythmia myocardial effects]. PMID- 4144784 TI - [Effect of ethaverin in heart diseases]. PMID- 4144785 TI - [Clinical use of ethaverin, a new antiarrhythmia agent]. PMID- 4144786 TI - Tetraphenylboron as direct titrant for diphasic determination of some organic bases. PMID- 4144787 TI - [Clinical-experimental studies on the bronchoconstrictor activity of Dalzic (ICI 50 172)]. PMID- 4144788 TI - [Comparison of the effects of propranolol, practolol, oxyprenolol and L.B. 46 on myocardial contractility]. PMID- 4144789 TI - [Propagation mechanism of the neurotropic Vaccinia virus strain in the rabbit organism]. PMID- 4144790 TI - [Buoyant density in CsCl of infectious feline Picorna virus virions]. PMID- 4144791 TI - Reproduction of Semliki Forest virus in poikilothermic and homeothermic cells at reduced temperatures. PMID- 4144792 TI - Method for the purification and concentration of Vaccinia-virus. PMID- 4144793 TI - Purification of smallpox vaccine with fluorocarbon. PMID- 4144794 TI - The combined effect of polyamines and antibiotics against resistant strains of Staphylococcus aureus. PMID- 4144795 TI - A study of staphylococci isolated from the upper respiratory tract of different animal species. V. Physiological properties of Staphylococcus aureus strains from mink. PMID- 4144796 TI - Problems in immunology of human salmonellosis. PMID- 4144797 TI - [Results of phage typing of Salmonella typhi and Salmonella paratyphi B in the years 1966-1969]. PMID- 4144798 TI - Bacteriocinogeny in Proteus-species. PMID- 4144799 TI - Studies on group A bacteriocins of Serratia marcescens: preliminary characterization of two subgroups of bacteriocins. PMID- 4144800 TI - Immunochemical studies and differential diagnosis of Brucella infections in sheep. PMID- 4144801 TI - The presence of Listeria monocytogenes in feces of pregnant women and neonates. PMID- 4144802 TI - [Usefulness of morphological methods in the diagnosis of mycoplasmas]. PMID- 4144803 TI - Enhancement of bacterial hemolysis by antibiotics. PMID- 4144805 TI - [Yersinia pseudotuberculosis, the pathogen of bovine matitis]. PMID- 4144804 TI - [Pathogenic effect of neuramindase in Trichomonas foetus]. PMID- 4144806 TI - Graft-versus-host reactions in mice. 3. Epithelioid and multinucleated giant cells of thymic origin. AB - Thymus cells from C3H donor mice were infused into lethally irradiated (C3H x C57BL/10)F(1) hybrid mice. Light and electron microscopic examination of the lymphoid tissues of recipients revealed the presence of epithelioid and multinucleated giant cells in addition to lymphocytes and histiocytes. Serial transplantation of thymus-derived cells into irradiated F(1) hybrid mice resulted in a preponderance of epithelioid cells over lymphocytes. Epithelioid cells, as well as lymphocytes and histiocytes, incorporated (3)H-thymidine, indicating that they were actively proliferating. Following transplantation of CBA-T6T6 thymocytes into irradiated (C3H x C57BL/10)F(1) mice, karyotypic analysis of host lymphoid tissues indicated that all dividing cells were of donor origin. Whereas bone marrow is known to give rise to epithelioid cells in the absence of thymic influences, the thymus must also contain precursors of epithelioid cells. PMID- 4144807 TI - Graft-versus-host reactions in mice. IV. Thymus cell suppression of antibody formation. AB - The ability of transplanted marrow-thymus cell mixtures to generate antibody forming cells in irradiated syngeneic or F(1) hybrid mice when immunized with sheep erythrocytes 18 hours later was determined. Much fewer anti-sheep plaque forming cells (PFC) were detected in spleens of F(1) hybrid mice. Adrenalectomy, use of infant recipient mice, or preimmunization of donors or hosts did not prevent the suppression; the grafting of irradiated donor-type spleen cells (source of "accessory" cells) produced only an additive effect. Parental marrow and thymus cells were able to generate new precursors of PFC and specific inducer cells, respectively, in spleens of F(1) hybrid mice, as detected by two-step experiments utilizing parent-strain secondary recipient mice. The suppression depended upon transferring parental strain thymus cells into F(1) hybrid mice and was seen irrespective of the marrow donor strain. When irradiated mice were immunized twice (on the day of transplantation and 4 days later), there was only marginal suppression of antibody production when marrow cells only or marrow plus thymus cells were transplanted. Thus, it appears that an excess of thymus-derived "suppressor" cells is generated upon exposure to alloantigens and inhibit terminal differentiation of antibody-forming cells in a noncytotoxic manner. Mature PFC themselves were not the targets of suppression. The method of immunization probably determines the relative functional capacity of thymus derived "helper" and suppressor cells. PMID- 4144808 TI - [Weight loss, bronchopneumonia, and uremia]. PMID- 4144809 TI - [Penetration of I-131-labeled bacterial antigens through intact dental enamel and dentin in vivo]. PMID- 4144810 TI - [Dental surgery in patients with implanted pacemaker]. PMID- 4144811 TI - Staffing the emergency department. PMID- 4144812 TI - Cardiac stimulant activity of the saponin of Achyranthes aspera (Linn). PMID- 4144813 TI - The oral and physical health of students entering dental school. PMID- 4144814 TI - Fluoride levels, fluorosis and dental caries: a study determining the optional level of fluoride from 15 communities. PMID- 4144815 TI - [Therapeutic aspects in cryptorchism]. PMID- 4144816 TI - Stimulation of tyrosine hydroxylase activity in an adrenergic clone of mouse neuroblastoma by dibutyryl cyclic AMP. PMID- 4144817 TI - [Enzymatic activity of sorbitol dehydrogenase (SDH) in the normal human cornea and in the cornea of various animals]. PMID- 4144818 TI - Interaction of aflatoxin B 1 metabolite with rat liver RNA. PMID- 4144819 TI - The binding of phenothiazines to oxyhemoglobin A and S. PMID- 4144820 TI - Effect of intravenous dibutyryl cyclic AMP on histamine-induced bronchospasm in the guinea pig. PMID- 4144821 TI - The effect of repeated administration of (-)- 9 -tetrahydrocannabinol on the biosynthesis of brain amines. PMID- 4144822 TI - Nurse education: the training of medical assistants in Rhodesia today. PMID- 4144823 TI - Cardiovascular effects of fenoterol. PMID- 4144824 TI - Cardiovascular effects of hexoprenaline sulphate and salbutamol in man. PMID- 4144825 TI - Binding of 14 C-carbon tetrachloride to microsomal proteins in vitro and formation of CHC1 3 by reduced liver microsomes. PMID- 4144826 TI - Oxidative drug metabolism in the perinatal rabbit liver and placenta. A biochemical and morphologic study. PMID- 4144827 TI - Sarcoplasmic reticulum in Duchenne muscular dystrophy. PMID- 4144828 TI - Association of pulmonary hypoplasia, renal anomalies, and Potter's facies. PMID- 4144829 TI - Diacetyl (acetoin) reductase from Aerobacter aerogenes. Kinetic mechanism and regulation by acetate of the reversible reduction of acetoin to 2,3-butanediol. PMID- 4144830 TI - Adaptive changes in satellite systems related to lipogenesis in rat and sheep mammary gland and in adipose tissue. PMID- 4144831 TI - Genetic variants of human erythrocyte glucose-6-phosphate dehydrogenase. Discrete conformational states stabilized by NADP + and NADPH. PMID- 4144832 TI - Evidence for the compartmentation of cholesterol in rat-liver microsomes. PMID- 4144833 TI - [Epidemiology of alcohol and drug addiction. Report on a WHO conference]. PMID- 4144834 TI - The inhibition of pineal hydroxyindole-O-methyltransferase by haloperidol and fluphenazine. PMID- 4144835 TI - Some properties of a water soluble phosphated nonylphenol ethoxylate. PMID- 4144836 TI - The effects of particle size, shape and moisture content on the tensile properties of procaine penicillin powders. PMID- 4144837 TI - An infrared study of the association between some 2,6-diamino-8,9-disubstituted purines and phenobarbitone in chloroform. PMID- 4144838 TI - Correlation of chromatographically obtained substituent constants and analgesic activity. PMID- 4144839 TI - The packing properties of moist beds of bulk solids. PMID- 4144840 TI - The effect of binding agents on some properties of granules of lithium carbonate and on the tablet porosity. PMID- 4144841 TI - Instrument of a hard shell encapsulation machine. PMID- 4144842 TI - The preparation of controlled release particles in the sub-sieve size range. PMID- 4144843 TI - Extracellular lipids of Pseudomonas aeruginosa obtained from liquid media by aqueous n-butanol. PMID- 4144844 TI - Production of pure cordycepin (3'-deoxyadenosine) from Cordyceps militaris. PMID- 4144845 TI - Elimination of an R-factor by trimethoprim. PMID- 4144846 TI - Centrifugal freeze-drying of spores of Penicillium chrysogenum WIS 54-1255 from sodium glutamate. PMID- 4144847 TI - Non-aqueous liquids as modifiers of lethal damage induced by Bacillus megaterium spores by gamma-rays. PMID- 4144848 TI - The interaction of Escherichia coli and magnesium trisilicate in aqueous suspension. PMID- 4144849 TI - The interaction between kaolinite and Staphylococcus aureus. PMID- 4144851 TI - The kinetics of thermal dehydration and transformation of solid cortisone acetate. PMID- 4144850 TI - Interaction of large organic ions of opposite charge and the calculation of extra thermodynamic substituent constants. PMID- 4144852 TI - The influence of polysorbate 20 on the transfer of salicylic acid across a Cellophane membrane. PMID- 4144853 TI - The adsorption of cetyl trimethylammonium bromide from mixed surfactant solutions. PMID- 4144854 TI - The effect of cetyltrimethylammonium bromide on the hydrolysis of p-substituted ethylbenzoates. PMID- 4144855 TI - The stability of aqueous solutions of promethazine hydrochloride as a function of pH. PMID- 4144856 TI - The stability of sulphafurazole when complexed with diethanolamine. PMID- 4144857 TI - Elastic recovery and surface area changes in compacted powder systems. PMID- 4144858 TI - An investigation of some of the factors influencing tablet strength. PMID- 4144859 TI - An evaluation of a new pore model for plastic matrix tablets. PMID- 4144860 TI - Surface geometry of some microcrystalline celluloses. PMID- 4144861 TI - Water vapour permeability of poured and sprayed polymer films. PMID- 4144862 TI - A preliminary study of the thermal and photochemical degradation of thiamine hydrochloride. PMID- 4144863 TI - The photodegradation of L-dopa and related compounds. PMID- 4144864 TI - Photolysis of a methaqualone metabolite. PMID- 4144865 TI - Coenzyme B 12 : correlation of ultraviolet, electrophoretic and enzyme assay methods. PMID- 4144867 TI - The determination of diamorphine by thin-layer chromatography and direct reflectance spectrophotometry. PMID- 4144866 TI - Photolytic decomposition of 3 cobalamins: a quantitative study. PMID- 4144868 TI - The determination of low concentrations of disulfiram by cathode ray polarography. PMID- 4144869 TI - The neuromuscular and other blocking actions of 4,17a-dimethyl-4,17a-diaza-D-homo 5 -androstane dimethiodide. PMID- 4144870 TI - Mechanisms of action of a hemicholinium analogue at the neuromuscular junction. PMID- 4144871 TI - Neuromuscular blocking and local anaesthetic activities of warifteine hydrochloride, an alkaloid isolated from Cissampelos ovalifolia D.C. PMID- 4144872 TI - Adrenoceptors in the central nervous system concerned with cardiovascular control. PMID- 4144873 TI - Effects of oestrogen and progesterone on brain monoamines: interactions with psychotropic drugs. PMID- 4144874 TI - Permanent changes in brain monoamine metabolism induced by the administration of psychotropic drugs during the pre- and neonatal periods in rats. PMID- 4144875 TI - The partial fate of aminoglutethimide in man. PMID- 4144876 TI - Screening drugs for ototoxicity. PMID- 4144877 TI - The application of a model T Coulter Counter to dissolution rate studies. PMID- 4144878 TI - Comparative dissolution rates of the anhydrous and trihydrate forms of ampicillin. PMID- 4144879 TI - The role of natural convection in the dissolution of salicylic acid. PMID- 4144880 TI - Some effects of micellar concentrations of polysorbate 20 on the dissolution rate of salicylic acid. PMID- 4144881 TI - Effect of certain non-ionic surface active agents on the electrophoretic mobility of polystyrene latices. PMID- 4144882 TI - Effect of the nature of the disperse phase on the stability of oil-in-water emulsions. PMID- 4144883 TI - Some investigations into the effect of cycling temperature on the drop size of an oil-in-water emulsion. PMID- 4144884 TI - Some effects of germination changes in fungal spores upon their resistance to chemical and physical agents. PMID- 4144885 TI - The influence of EDTA and PEA upon the fungistatic action of aminoacrine hydrochloride. PMID- 4144886 TI - Preliminary investigation of the preservative properties of 3-phenylpropanol. PMID- 4144887 TI - Preservation of sulphacetamide eye drops. PMID- 4144888 TI - The uptake by Escherichia coli and growth inhibitory properties of methyl, ethyl and propyl p-hydroxybenzoates. PMID- 4144889 TI - The uptake of chloroquine by Escherichia coli. PMID- 4144890 TI - The effect of pH on the inhibitory activity of chloroquine against Escherichia coli. PMID- 4144891 TI - A structural least squares method for oral absorption constants. PMID- 4144893 TI - The binding of amphetamine and related compounds to plasma protein. PMID- 4144892 TI - The effect of chloroquine and its congeners on mitochondrial oxidation. PMID- 4144894 TI - The determination of protein-binding by the Hammett rho constant for O-hydroxyl. PMID- 4144895 TI - Aluminium hydroxide and pepsin. PMID- 4144896 TI - Intestinal absorption of macroanions. PMID- 4144897 TI - Synthesis of spiro(oxindole-3,2'-bicyclo(2.2.1)hept-5'-ene)derivatives. PMID- 4144898 TI - Further investigation of the sterol ester fraction of Digitalis purpurea L. PMID- 4144899 TI - The identification of peptide alkaloids from Euonymus europaeus L. (Celastraceae). PMID- 4144900 TI - N-oxides isolated during the alkaloid screening of Uncaria species. PMID- 4144901 TI - Iridoid content of some Scrophularia species. PMID- 4144902 TI - The interaction of penicillins with phospholipids. PMID- 4144903 TI - The influence of solvents on the sorption of benzocaine by nylon 6 (polycaprolactam). PMID- 4144904 TI - Zinc and copper(II) ion catalyses of penicillins in alcohols. PMID- 4144905 TI - A correlation between solubility and carminative activity. PMID- 4144906 TI - Distribution coefficients and anabolic activities of some nandrolone esters. PMID- 4144907 TI - Placebo response to white soft paraffin-propylene glycol in skin blanching test. PMID- 4144908 TI - Continuous shear, viscoelastic and spreading properties of a new topical vehicle, FAPG base. PMID- 4144909 TI - Viscoelastic properties of pharmaceutical semi-solids: characterization of the Plastibases for bioavailability studies. PMID- 4144910 TI - Oscillatory testing of o-w emulsions containing mixed emulsifiers of the surfactant-long chain alcohol type: self-bodying action. PMID- 4144911 TI - Formulation of a sterile surgical lubricant. PMID- 4144912 TI - A study of the formulation of steroidal suspensions. PMID- 4144913 TI - The effect of particle size on the granulation of lactose by massing and screening. PMID- 4144914 TI - Some physical characteristics of magnesium stearate. PMID- 4144915 TI - Penicillin resistance in Staphylococcus aureus 893 not mediated by -lactamase. PMID- 4144916 TI - Determination of thermodynamics of the methylene group in solutions of drug molecules. PMID- 4144917 TI - The effect of temperature on the mechanical properties of some pharmaceutical powders in relation to tableting. PMID- 4144918 TI - Thermoelastic properties of preformed compacts. PMID- 4144919 TI - Comparison of oral and percutaneous routes in man for the systemic administration of 'ephedrines'. PMID- 4144920 TI - Stabilization of oil-in-water emulsions by alkyl sulphates: the influence of the nature of the oil on stability. PMID- 4144921 TI - Changes in antibacterial activity of thiomersal and PMN on autoclaving with certain adjuvants. PMID- 4144922 TI - Effect of polysorbate 80 and phenylethanol on the antibacterial activity of fentichlor. PMID- 4144923 TI - [Bioassay of various anti-ulcer drugs using the clamping-cortisone ulcer--with special reference to the tissue and numerical analysis]. PMID- 4144924 TI - -Glutamyltranspeptidase activity in the urine of healthy individuals and patients suffering from kidney diseases. PMID- 4144925 TI - Eosinophilia following radiation therapy. PMID- 4144926 TI - [Study of glutamine synthetase of Candida tropicalis fodder yeast]. PMID- 4144927 TI - [Extramural experiences. Statistics, results and comments]. PMID- 4144928 TI - [Dentistry and boxing]. PMID- 4144929 TI - [Dental caries, periodontal disease and oral hygiene in 6-17-year-old male children]. PMID- 4144930 TI - [Treatment of essential pruritus]. PMID- 4144931 TI - [Behavior of gamma glutamyl transpeptidase in hepatobiliary diseases]. PMID- 4144932 TI - [The fractionation of AuA-containing serum (plasma) with rivanol and on sephadex columns]. PMID- 4144933 TI - Factors affecting the coagulase release by Staphylococcus aureus. PMID- 4144934 TI - [The occurrence of Plesiomonas chigelloides in man]. PMID- 4144935 TI - [A selective medium with hexamethyl phosphoric acid triamide for isolation of atypical mycobacteria]. PMID- 4144937 TI - [A selective culture medium for the detection of Aspergillus flavus in molded bread]. PMID- 4144936 TI - Effect of growth-regulating substances on the biomass and lipids of some fungi. PMID- 4144938 TI - [Polyomavirus hemagglutinin and antibody determination by use of the photometric HCU and ACU method]. PMID- 4144939 TI - A study on cytomegalovirus by the gel precipitation method. PMID- 4144940 TI - [Brain involvement in viral diseases. I. Histological studies in children suffering from acute hyperpyretic toxicosis]. PMID- 4144941 TI - [Salmonellae in faeces of seagulls on the Baltic coast]. PMID- 4144942 TI - [Comparative studies with the electron microscope of bacteria belonging to the group Acinetobacter]. PMID- 4144943 TI - [Selenomonas in the caecum of rats]. PMID- 4144944 TI - [The effect of Clostridium butyricum (strain M 55) on human kininogen and its significance for the process of oncolysis]. PMID- 4144945 TI - [Study of the gastro-intestinal microflora of suckling piglets and early weaned piglets reared using different feeding systems]. PMID- 4144946 TI - [The combination sulfamethoxazole-trimethoprim in vitro]. PMID- 4144947 TI - [Scanning electron microscopy studies on the effect of endotoxin on the capillary bed]. PMID- 4144949 TI - [New Salmonella type: S hiduddify]. PMID- 4144948 TI - [Toxicity, pyrogenicity and antigenicity of a bacterial lipopolysaccharide treated with hydroxylamine]. PMID- 4144950 TI - The role of effluents in the spread of Salmonellae. PMID- 4144951 TI - [Demonstration of the enzymes neuraminidase and diphthin by immunoelectrophoresis as an aid in the diagnosis of Corynebacterium diphtheriae]. PMID- 4144952 TI - Sleeping sickness survey in the Serengeti area (Tanzania) 1971. I. Examination of large mammals for trypanosomes. PMID- 4144953 TI - Exocytosis in Entamoeba. PMID- 4144954 TI - Morphological changes in human schistosomiasis and certain analogies in ancient Egyptian sculpture. PMID- 4144955 TI - Sleeping sickness survey in the Serengeti area (Tanzania) 1971. II. The vector role of Glossina swynnertoni Austen. PMID- 4144956 TI - Sleeping sickness survey in the Serengeti area (Tanzania) 1971. 3. Discussion of the relevance of the trypanosoma survey to the biology of large mammals in the Serengeti. PMID- 4144957 TI - Isolation of Trypanosoma (Trypanozoon) rhodesiense from game and domestic animals in Musoma District, Tanzania. PMID- 4144958 TI - Histological examination of wild animals naturally infected with pathogenic African trypanosomes. PMID- 4144959 TI - On the ultrastructure of Trypanosoma (Trypanozoon) brucei in the course of its life cycle and some related aspects. PMID- 4144960 TI - Glutamine synthetase of the nitrogen-fixing alga Anabaena cylindrica. PMID- 4144961 TI - [Action and tolerance of Proclival. Study on 38 cases of essential arterial hypertension]. PMID- 4144962 TI - The effects of aflatoxin B 1 in vivo on membrane--ribosome association. AB - The effects of aflatoxin B(1) on the endoplasmic reticulum of rat liver has been examined in vivo. Electron microscopy has shown a disorganization and degranulation of rough surfaced membrane under these conditions and evidence is presented that this is a primary effect of the toxin, and results from the direct attack of the aflatoxin on the steroid-dependent ribosome binding sites on the membrane. A technique is described by which the presence of degranulated rough membrane may be detected in microsomal preparations. PMID- 4144963 TI - [In vitro study of characteristics of 5 alpha-delta 4 steroid reductase from Nocardia corallina]. PMID- 4144964 TI - [NAD and NADP ferredoxin reductase activities of acellular extracts from Clostridium pastorianum]. PMID- 4144965 TI - Physiological and behavioural processes in early maternal deprivation. PMID- 4144966 TI - Changes in catecholamine-controlling enzymes in response to psychosocial activation of the defence and alarm reactions. PMID- 4144967 TI - Conservation-withdrawal: a primary regulatory process for organismic homeostasis. PMID- 4144968 TI - Characterization of a serum inhibitor of MLC reactions. PMID- 4144969 TI - Improving information exchange between scientists and representatives of the communications media: conference II. PMID- 4144970 TI - Chronic granulomatous disease--pieces of a cellular and molecular puzzle. PMID- 4144971 TI - [Fertility disorders in males. Prevention, diagnosis and therapy from the andrological view point]. PMID- 4144972 TI - Annual administrative reviews: nursing. PMID- 4144973 TI - Annual administrative reviews: hospital-physician relations. PMID- 4144974 TI - Health manpower and the education of health personnel: comment. PMID- 4144975 TI - [Etiology and treatment of nocturnal sural cramps]. PMID- 4144976 TI - [A working session on pulmonary and nasal function]. PMID- 4144977 TI - Review of the Intra-Science Research Foundation Symposium on the chemistry and pharmacology of prostaglandins. PMID- 4144978 TI - [The harmful consequences of vibration (a survey of the foreign literature)]. PMID- 4144979 TI - [Pediatric urology for the general practitioner]. PMID- 4144981 TI - The psychotherapy of schizophrenia: an NIMH program. PMID- 4144980 TI - [Pathergy to humidity. Hydrogeological study of the Brussels region]. PMID- 4144982 TI - [Technic of gamma glutamyl transpeptidase determination in human serum, using a semi-automatic LKB apparatus]. PMID- 4144983 TI - Antihistaminic activity of 4-(2, 1, pyrrolidino-ethoxy) quinoline. PMID- 4144984 TI - Tumor induction by immunologically activated murine leukemia virus. AB - A graft-vs.-host reaction (GVHR) was induced in young male CAF(I) and CB6F(1) mice by the administration of BALB/cJ spleen cells. A proportion of such mice subsequently developed lymphoreticular rumors. Cell-free extracts (CFEs) prepared from the reticular tissues of CAF(1) mice killed at intervals after the induction of the GVHR were tested for their capacity to produce the same tumors in a litter of syngeneic mice inoculated at birth. 12 of 29 (41.4%) such extracts were positive, causing lymphoreticular tumors in one or more littermate recipients. The positive CFEs came from donors killed at all stages of the GVHR, from tumor bearing mice as well as from non-tumor-bearing mice. However, whereas less than 30% of CFEs from mice killed within 12 mo of GVHR induction were oncogenic, the incidence of oncogenic extracts from mice killed 12-15 mo after GVHR induction rose to 75%. None of the CFEs prepared from nine normal uninjected male CAF(1) mice killed between the ages of 8 and 18 mo transmitted tumors to recipients. CFEs prepared from CAF(1) mice with the GVHR were tested for infectious murine leukemia virus (MuLV) using the XC assay and also for complement-fixing (CF) group-specific MuLV antigen. Substantial titers of B-tropic MuLV and CF antigen were detected in at least half the extracts from mice killed 11-14 mo after GVHR induction. During the first few months of GVHR induction, MuLV titers were low and CF antigen was absent. Neither infectious MuLV nor CF antigen were detected in CFEs prepared from normal control mice. Serially passed CFEs originating from a CB6F(1) GVHR-induced RCN caused similar tumors in successive generations of syngeneic recipient mice. These lymphoreticular tumors were shown to contain infectious MuLV, CF MuLV antigen, and C-type particles. These data together provide evidence that MuLV is activated during the GVHR and that it is responsible for the eventual development of lymphoreticular tumors. PMID- 4144985 TI - Graft-versus-host reactions across different regions of the H-2 complex of the mouse. AB - H-2 crossovers and their parental strains were arranged into 35 combinations in which the adult donor of spleen cells differed from the newborn recipient in the whole H-2 complex, or in three, two, or one region of the complex. A Simonsen splenomegaly assay was then used to test the contribution of the individual H-2 regions to the graft-versus-host reaction (GVHR). It was shown that the strongest GVHR was associated with the Ir region. Differences in the Ir region caused significant splenomegaly in spite of the fact that no antigens detectable by conventional serological methods have thus far been associated with this region. Differences in the K and D regions showed only a borderline effect on GVHR in spite of the fact that these regions code for most, if not all, of the antigens detectable by conventional serological and transplantation methods. The K region alone caused no stronger GVHR than the D legion alone; however, K + Ir region differences led to much stronger GVHR than D region differences. The Ss-Slp region also showed only a borderline effect on GVHR. Differences in two or more H 2 regions usually caused greater splenomegaly than differences in each of the regions separately. On the basis of these findings it is concluded that the strongest GVHR is caused by genes distinct from the known histocompatibility genes of the H-2 complex. It is speculated that the GVHR genes are identical with the mixed lymphocyte reaction (MLR) and Ir genes and that the product of these genes are receptors on the surface of the thymus-derived lymphocytes (T cells). PMID- 4144988 TI - The surgeon's assistant in private surgical practice and in the university hospital. PMID- 4144987 TI - Fear-provoking recommendations, intentions to take preventive actions, and actual preventive actions. PMID- 4144986 TI - Mechanism of graft-versus-host-induced lymphadenopathy in mice. Trapping vs. proliferation. AB - Graft-vs.-host (GVH)-induced lymphadenopathy of the popliteal lymph node has been produced in C57BL/6 x A/J F(1) (BAF(1)) mice by injecting A/J spleen cells into the rear footpads. By giving (51)Cr-labeled BAF(1) lymphoid cells intravenously to the hosts, 24 h before sacrifice, we have demonstrated that a large portion of the GVH-induced lymphadenopathy is due to the trapping of circuating lymphocytes in the challenged lymph nodes. Most of the remaining enlargement can be attributed to proliferation of host cells within the reacting lymph nodes. Conditions have been defined under which the weights and [(14)C]thymidine incorporation of the popliteal nodes can be plotted against the dose of injected A/J spleen cells on a double-log scale to give a linear dose-response. The popliteal lymph node GVH assay is a simple and effective means of quantitating immune reactivity to histocompatibility antigens in mice. PMID- 4144989 TI - The importance of dosage in antipsychotic drug administration--a review of dose response studies. PMID- 4144990 TI - Amoxycillin (Amoxil) in the treatment of respiratory disease in children. PMID- 4144991 TI - [Effect of benzohexonium and hexamethonium on the pulmonary circulation and the contractile function of the myocardium]. PMID- 4144992 TI - [Practolol in anesthesia (ICI 50.172, Eraldin)]. PMID- 4144993 TI - The preparation of soluble high molecular weight NAD derivative active as a cofactor. PMID- 4144994 TI - On the solubilization of NADPH-cytochrome c reductase from rat liver microsomes with crude pancreatic lipase. PMID- 4144995 TI - [The life and work of feldsher G.V. Sidochenko]. PMID- 4144996 TI - Treatment patterns in psychiatry: relationships to symptom features and aging. PMID- 4144997 TI - [Poisoning with antihistaminics]. PMID- 4144998 TI - [Australia antigen and the agents of hepatitis. Serologic methods for detection and electron microscopy]. PMID- 4144999 TI - Au-SH antigen, hepatitis, and polyarteritis nodosa. PMID- 4145000 TI - Psychophysiological discriminants of reactive depression. PMID- 4145001 TI - [Classification of rheumatic diseases]. PMID- 4145002 TI - Histamine: effect on self-stimulation. AB - When injected discretely into the lateral hypothalamus of rats, histamine inhibited electrical self-stimulation at the injection site without affecting self-stimulation in the contralateral lateral hypothalamus. This effect was blocked by prior treatment with antihistaminics. Histidine, the amino acid precursor of histamine, produced a similar effect after a delay of 6 to 10 minutes. PMID- 4145003 TI - [Erythrocyte metabolism in acquired hemolytic and refractory anemias]. PMID- 4145004 TI - Malignancy as a complication of immunosuppressive therapy. PMID- 4145005 TI - The Navy dermatology technician. A survey of his attitudes and aspirations. PMID- 4145006 TI - [Further searches for beta-adrenoblocking agents in the aroxyalkanolamine series]. PMID- 4145007 TI - Acute respiratory distress syndrome in adults. Definition, etiology and treatment. PMID- 4145008 TI - Neurospora 6-phosphogluconate dehydrogenase. II. Properties of two purified mutant enzymes. PMID- 4145010 TI - Differences between germ-free and conventional rats in liver microsomal metabolism of steroids. PMID- 4145009 TI - Stimulation of 32 P i incorporation into phosphatidylinositol and phosphatidyglycerol by catecholamines and -adrenergic receptor blocking agents in rat pineal organ cultures. PMID- 4145011 TI - [Ultrastructural study of spermatogenesis in the ctenophoran, Beroe ovata]. PMID- 4145012 TI - Autonomic dysreflexia in injuries below the sixth thoracic segment. PMID- 4145014 TI - [Periarteritis nodosa and Australia antigen]. PMID- 4145015 TI - [Measures for reducing the rate of complications following smallpox vaccination]. PMID- 4145016 TI - [Report on an international Chloramphenicol-Thiamphenicol Symposium in Sils Maria GR, Switzerland (changing effects between drug and host known and unknown aspects)]. PMID- 4145013 TI - Measurement of hydrophobicity, surface activity, local anaesthesia, and myocardial conduction velocity as quantitative parameters of the non-specific membrane affinity of nine -adrenergic blocking agents. PMID- 4145018 TI - Dental health of four-year-old children. PMID- 4145017 TI - Valve replacement: present status of homograft valves. PMID- 4145019 TI - Restricted riboflavin: within-subject behavioral effects in humans. PMID- 4145020 TI - Correlation of alcohol and tolbutamide blood clearance rates with microsomal alcohol-metabolizing enzyme activity. PMID- 4145021 TI - [Tolerance to living cells]. PMID- 4145022 TI - [Anti-arrhythmic effect of a new adrenergic beta receptor blocking substance]. PMID- 4145023 TI - Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria. PMID- 4145024 TI - Oxidative phosphorylation in Escherichia coli K-12: the genetic and biochemical characterisations of a strain carrying a mutation in the uncB gene. PMID- 4145025 TI - Specific leukocyte receptors for small endogenous hormones. Detection by cell binding to insolubilized hormone preparations. AB - Receptors for small endogenous hormones on human leukocytes were studied by insolubilizing the hormones and incubating them with the cells. Histamine, norepinephrine, and prostaglandin E(2) (PGE(2)) were conjugated to either of two types of carrier: (bovine or rabbit) serum albumin or a random copolymer of DL alanine and L-tyrosine. The conjugates were linked to agarose beads (Sepharose) and the resultant drug-conjugate-beads were incubated with leukocytes. Norepinephrine (when linked to its carrier via glutaraldehyde) and histamine preparations bound the majority of leukocytes. The binding appeared to be specific for the hormones tested. For example, the binding by histamine-rabbit serum albumin-Sepharose was prevented or reversed by high concentrations of histamine and histamine antagonists, but not by catecholamines or their pharmacologic antagonists. Similarly, binding of cells to the norepinephrine conjugate was inhibited by some catecholamines and propranolol, but not by histamine or histamine antagonists. Conjugates of norepinephrine linked via carbodiimide did not bind cells. The protein or copolymer carriers did not contribute to binding per se. The hormone-protein-conjugates bound more cells than the hormone-polymer conjugates. The former (unlike the free amines) failed to stimulate accumulation of cyclic AMP in leukocytes. The norepinephrine linked to polymer via glutaraldehyde, however, did stimulate leukocyte cyclic AMP accumulation, possibly because of the flexibility of the polymer. Columns of the various Sepharoses were used to determine the distribution of receptors to each hormone in mixed leukocyte populations. The majority of cells appeared to have receptors for both histamine and norepinephrine (bound through glutaraldehyde). Receptors to prostaglandins may have been detected by the column procedure, but their distribution could not be quantitated. The approach described provides a means to separate leukocytes on the basis of what are likely to be preformed receptors to small endogenous hormones, and to study the physiologic importance and function of the receptors. PMID- 4145027 TI - Pneumonia and pulmonary infarction in sickle cell anemia. PMID- 4145026 TI - In vitro antibody-enzyme conjugates with specific bactericidal activity. AB - IgG with antibacterial antibody opsonic activity was isolated from rabbit antisera produced by intravenous hyperimmunization with several test strains of pneumococci, Group A beta-hemolytic streptococci, Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa, and Escherichia coli. Antibody-enzyme conjugates were prepared, using diethylmalonimidate to couple glucose oxidase to IgG antibacterial antibody preparations. Opsonic human IgG obtained from serum of patients with subacute bacterial endocarditis was also conjugated to glucose oxidase. Antibody-enzyme conjugates retained combining specificity for test bacteria as demonstrated by indirect immunofluorescence. In vitro test for bactericidal activity of antibody-enzyme conjugates utilized potassium iodide, lactoperoxidase, and glucose as cofactors. Under these conditions glucose oxidase conjugated to antibody generates hydrogen peroxide, and lactoperoxidase enzyme catalyzes the reduction of hydrogen peroxide with simultaneous oxidation of I(-) and halogenation and killing of test bacteria. Potent in vitro bactericidal activity of this system was repeatedly demonstrated for antibody-enzyme conjugates against pneumococci, streptococci, S. aureus, P. mirabilis, and E. coli. However, no bactericidal effect was demonstrable with antibody-enzyme conjugates and two test strains of P. aeruginosa. Bactericidal activity of antibody-enzyme conjugates appeared to parallel original opsonic potency of unconjugated IgG preparations. Antibody-enzyme conjugates at concentrations as low as 0.01 mg/ml were capable of intense bactericidal activity producing substantial drops in surviving bacterial counts within 30-60 min after initiation of assay. These in vitro bactericidal systems indicate that the concept of antibacterial antibody-enzyme conjugates may possibly be adaptable as a mechanism for treatment of patients with leukocyte dysfunction or fulminant bacteremia. PMID- 4145028 TI - [Effect of "specific" cardiac adrenergic inhibitors on ventilatory function in bronchial asthma]. PMID- 4145029 TI - The top drugs. Inderal--blocking beta receptors. PMID- 4145030 TI - [The possibility of determining female mosquitoes by microscopic preparations of the head. II. A key to the genera and subgenera]. PMID- 4145031 TI - [Bloodsucking dipteran insects of the central districts of Magadan Province]. PMID- 4145032 TI - T-lymphocyte function following burns: dependence of response on antigenic disparity and size of injury. PMID- 4145033 TI - Evidence for two separate adenyl cyclase systems responding independently to parathyroid hormone and -adrenergic agents in the renal cortex of the rat. PMID- 4145035 TI - Cellular heterogeneity in the thymus: graft-versus-host activity of fractionated thymus cells in the chicken. PMID- 4145034 TI - "Xenogeneic resistance" to rat bone marrow transplantation. I. The basic phenomenon. PMID- 4145036 TI - [Trends of therapy in states of so-called hypoxemic-hypercapnic respiratory insufficiency]. PMID- 4145037 TI - Photoreduction of ferredoxin-NADP in the presence and absence of ferredoxin reducing substance (FRS). PMID- 4145038 TI - [Influence of some vasodilator agents on coronary flow]. PMID- 4145039 TI - [Practolol in supraventricular arrhythmias]. PMID- 4145040 TI - Comparative effects of cytotoxic agents on transplanted hematopoietic and antibody-producing cells. PMID- 4145041 TI - Effect of aminoacetonitrile on the fine structure and cytochemistry of hepatic cells in rats fed two carcinogenic N-nitrosodialkylamines. PMID- 4145043 TI - Nitroreductase activity of mammalian liver aldehyde oxidase. PMID- 4145042 TI - Chronic administration of chlorcyclizine and meclizine to rats: accumulation of a metabolite formed by piperazine ring cleavage. PMID- 4145044 TI - Drug stimulation of -aminolevulinic acid synthetase and cytochrome P-450 in vivo in chick embryo liver. PMID- 4145045 TI - Studies on the cytochrome P-450-containing mono-oxygenase system in human kidney cortex microsomes. PMID- 4145046 TI - Relative beta adrenergic receptor blocking activity in dogs after intravenous and intraportal vein administration: bunolol, propranolol, their levo isomers and sotalol. PMID- 4145047 TI - [Thoracic lesion in collagen diseases]. PMID- 4145049 TI - [Lunar mission with the Apollo 17]. PMID- 4145048 TI - Renal lesions with organized deposits and lipid as part of the host versus graft syndrome in parent-F 1 mouse chimeras. PMID- 4145050 TI - [Human factors in relationship to the development of pressurized cabins]. PMID- 4145052 TI - Effects of stimulants on observed behaviour of rats on six operant schedules. PMID- 4145051 TI - [Use of drugs by flight personnel during a flight]. PMID- 4145053 TI - Effects of neurohumoral and adrenergic agents on cyclic AMP levels in various areas of the rat brain in vitro. PMID- 4145055 TI - [Reactivity of collagen and elastic fibers under various experimental conditons]. PMID- 4145054 TI - Inhibition of adrenergic neurotransmission by clonidine: an action on prejunctional -receptors. PMID- 4145056 TI - Assessment of the susceptibility of females of several species of mosquitoes to infection with tick-borne encephalitis virus. PMID- 4145058 TI - Mosquito reduction by five spider species in conditions of competition of predator pairs. PMID- 4145057 TI - [Use of new synthetic pyrethrinoids in insect control at the medical and veterinary level]. PMID- 4145059 TI - [Recolonization of the spleen after autotransplantation of protected bone marrow in the irradiated rat]. PMID- 4145061 TI - Aging of the placenta: autoimmune theory of senescence. PMID- 4145060 TI - The promise of pharmacologic modification of ovum transport in contraceptive development. PMID- 4145062 TI - Kinetics of CO and O 2 complexes of rabbit liver microsomal cytochrome P 450 . PMID- 4145063 TI - Evidence for formation of oxygenated flavins. PMID- 4145064 TI - Experimental conservation and delayed expression of labile templates for enzyme synthesis in neural cells. PMID- 4145065 TI - Heterogeneity of hepatic mixed function oxidases. PMID- 4145066 TI - Oxidative phosphorylation in mutants of Escherichia coli defective in energy transduction. PMID- 4145067 TI - Hydrazobenzene oxidation by 2,6-dichlorophenol-indophenol in a photoreaction catalyzed by system I of photosynthesis. Hydrazine compounds as donors for photosystem II. PMID- 4145068 TI - Canadian Colloquium on Computer-Assisted Interpretation of Electrocardiograms. PMID- 4145069 TI - [Acute poisoning and intolerance of phenothiazine compounds of the piperazine type]. PMID- 4145070 TI - The effect of -adrenergic stimulation on the contractile response of canine detrusor muscle. PMID- 4145071 TI - Enzyme patterns in mitochondria of mouse liver and heart muscle. PMID- 4145072 TI - Glutamine synthetase in the avian diencephalon. PMID- 4145073 TI - An innovation in health care delivery in workman's compensation. PMID- 4145074 TI - [Sino-atrial block in inderal and digoxin treatment]. PMID- 4145075 TI - [Severe allergic reaction to ichthyol]. PMID- 4145076 TI - Some enzymatic activities in the bile in chronic hepatopathies (gamma-glutamyl transpeptidase, transaminases and ceruloplasmin). PMID- 4145077 TI - [Advances in the knowledge of new anti-dysrhythmic drugs]. PMID- 4145078 TI - Phthalate ester residues--their metabolism and analysis in fish. PMID- 4145079 TI - The ubiquitous nature and objectionable characteristics of phthalate esters in aerospace technology. PMID- 4145080 TI - [The use of extraction photometry in the analysis of paramyon]. PMID- 4145081 TI - [Clinical microbiology of lincomycin antibiotics]. PMID- 4145082 TI - Association of the two glycosyl transferase activities of glycoprotein synthesis with low equilibrium density smooth microsomes. PMID- 4145083 TI - The physician assistant in Maine: two pending proposals. PMID- 4145084 TI - [Effects of beta receptor stimulation on systole duration and temporal artery pulse in orthostasis conditions]. PMID- 4145085 TI - [Experiences with the new beta sympatholytic agent Dalzic (ICI 50 172)]. PMID- 4145086 TI - Hyperosmolar nonketotic diabetic coma: a complication of propranolol therapy. PMID- 4145087 TI - Effects of a simulated spacecraft environment on the oral microflora of nonhuman primates. PMID- 4145088 TI - Leary's interpersonal diagnosis in mothers of severely disturbed children attending a therapeutic nursery. PMID- 4145089 TI - Primary affective disorder: delineation of a unipolar depressive subtype. PMID- 4145090 TI - Carbon dioxide sensitivity and personality. PMID- 4145091 TI - Personality differences between inflammatory bowel disease patients and their healthy siblings. PMID- 4145092 TI - [Current trends of research on fatigue]. PMID- 4145093 TI - [Cardiotoxic drugs]. PMID- 4145094 TI - [Glutaraldehyde as coupling reagent for the preparation of ferritin-labelled antibodies]. PMID- 4145095 TI - [Problems encountered in the preparation of bacterial conjugates. I. Testing the suitability of bacterial antisera for labelling, and the influence of immunoglobulin isotypes]. PMID- 4145097 TI - [Microbiological, biochemical and pharmacokinetic studies with the new antibiotic cyclacillin]. PMID- 4145096 TI - [Problems encountered in the preparation of bacterial conjugates. II. The activity of purified antibodies of the IgM and IgG types in immunofluorescence]. PMID- 4145098 TI - [Quantitative determination of hepatitis associated antigen (HAA, Australia SH antigen)]. PMID- 4145099 TI - A new Salmonella spezies: S. bulgaria = 6,8:y:1,6. PMID- 4145100 TI - [Isolation of L. monocytogenes by nalidixic acid trypaflavine]. PMID- 4145101 TI - [Antibodies against arboviruses in starlings (Sturnus vulgaris L.) in Austria]. PMID- 4145102 TI - [Studies on the isolation of injured salmonellae from foods]. PMID- 4145103 TI - [Further observations on the occurrence of hepatitis associated antigen (HAA) in patients with viral hepatitis]. PMID- 4145104 TI - [Immunological investigations on E. coli strains related to Shigellae]. PMID- 4145105 TI - [Significance of citrobacteres as secondary invaders of the human respiratory tract]. PMID- 4145106 TI - [Inhibition of transformation in Hemophilus influenzae by addition of various substances]. PMID- 4145107 TI - Large-scale production of pertussis vaccine by serial subculture technic. PMID- 4145108 TI - [Serology of Bordetella pertussis. II. Preparation of ultrasonic extract of B. pertussis and its column chromatography on DEAE-cellulose]. PMID- 4145109 TI - [Further studies on the isolation of L. monocytogenes in clinically healthy individuals]. PMID- 4145110 TI - [Mycobacterium lycopinogenes, a new species]. PMID- 4145111 TI - [Creatine and creatinine assimilation by Sporothrix schenckii]. PMID- 4145112 TI - Studies of the hemopoietic microenvironment. 3. Differences in the splenic microvascular system and stroma between SL-SL d and W-W v anemic mice. PMID- 4145113 TI - [Penetrating keratoplasty in the treatment of keratoconus. Apropos of 60 cases]. PMID- 4145115 TI - Letter to the Editor--"Technicians to administer anesthesia". PMID- 4145114 TI - Comparative toxicity of isoflurane, halothane, fluroxene and diethyl ether in human volunteers. PMID- 4145117 TI - In vitro sensitization to transplantation antigens. VII. Enhanced graft-vs-host activity of in vitro allosensitized lymphoid cells. PMID- 4145116 TI - Management of the undescended testis. AB - Surgical correction of the undescended testis is frequently postponed beyond the optimal time, namely, 6 years of age.An accurate diagnosis of undescended testis may be made during the first year of life. Complications and mistakes arising from misdiagnosis of undescended testis and retracted testis may, therefore, be prevented by recording findings.The purpose of this article is to present the arguments in favour of early diagnosis and operative treatment of undescended testis, and to correct possible misconceptions. PMID- 4145118 TI - Immunosuppressive effect of graft-versus-host reaction. PMID- 4145119 TI - Chicken Harder's gland: evidence for a relatively pure bursa-dependent lymphoid cell population. PMID- 4145120 TI - Impurity in gamma-glutamyl p-nitroanilide used as substrate for D-glutamyl transferase. PMID- 4145121 TI - Public hospitals--critical or recovering? PMID- 4145122 TI - Selection of physician's assistants. PMID- 4145123 TI - Accreditation of physician's assistant programs. PMID- 4145124 TI - [Efficient liver function test]. PMID- 4145125 TI - [Side-effects of hormonal therapy for cryptorchism]. PMID- 4145126 TI - [NAD + - and NADP + -dependent dehydrogenases of the outer segments of the retina]. PMID- 4145127 TI - Investigations on correlations between serum enzymes and histological findings in liver disease. With special reference to transaminases and urocanase. PMID- 4145128 TI - Mannitol and sorbitol catabolism in Streptococcus mutans. PMID- 4145129 TI - Human caries vulnerability: is this affected by restorations or cavities at adjacent surfaces? PMID- 4145130 TI - The external NADH dehydrogenases of intact plant mitochondria. PMID- 4145131 TI - Complex formation by ferredoxin-NADP reductase with ferredoxin or NADP. PMID- 4145132 TI - The effect of temperature of the rate of photosynthetic electron transfer in chloroplasts of chilling-sensitive and chilling-resistant plants. PMID- 4145133 TI - Light-induced changes of bound chloroplast plastocyanin as studied by EPR spectroscopy: the role of plastocyanin in noncyclic photosynthetic electron transport. PMID- 4145134 TI - The participation of cytochromes in the process of nitrate respiration in klesbsiella (Aerobacter) aerogenes. PMID- 4145135 TI - Oxidation of reduced nicotinamide hypoxanthine dinucleotide by intact rat liver mitochondria. PMID- 4145137 TI - Conference on heart disease in community medicine. PMID- 4145136 TI - Selective attention and performance in dangerous environments. PMID- 4145138 TI - Methaqualone overdose: analytical methodology, and the significance of serum drug concentrations. PMID- 4145140 TI - NAPNES' 32nd Annual Convention. PMID- 4145139 TI - [Late extrapyramidal hyperkinesia during long-term administration of mebhydrolin]. PMID- 4145142 TI - The 1st Annual General Conference of Pakistan Nurses Federation. PMID- 4145141 TI - Minneapolis: NLN-NSNA Conventions, 1973. PMID- 4145143 TI - [Immunological competence in Hodgkin's disease]. PMID- 4145144 TI - The genetics of mimetic colour polymorphism in the large narcissus bulb fly, Merodon equestris Fab. (Diptera: Syrphidae). PMID- 4145145 TI - Colonisation of dead plants by Cryptococcus neoformans. PMID- 4145146 TI - [Effect of ultra-long-acting sulphonamide, sulphamethoxypyrazine (Longum Kelfizina) on the proliferative phase of replication of Toxoplasma gondii in NMRI mice. Contribution to experimental chemotherapy of toxoplasmosis]. PMID- 4145147 TI - [Occurrence of enterotoxin producing staphylococci in man]. PMID- 4145148 TI - [Characterization and purity testing of a complement-fixing N-D-polioviri on-type I-antigen for routine diagnosis and intratypic serodifferentiation]. PMID- 4145149 TI - [Effects of staphylococcal alpha-toxin on migration of free peritoneal cells]. PMID- 4145150 TI - The possible role of bacteriocins in the disappearance in vivo of the L-phase of group A hemolytic streptococci. PMID- 4145151 TI - [Differential diagnosis of Salmonella-sub-genera II and 3]. PMID- 4145152 TI - [Pyocine typing of Pseudomonas aeruginosa]. PMID- 4145153 TI - Ethylenediamine tetra-acetic acid (EDTA) induced morphological changes in Proteus mirabilis. PMID- 4145154 TI - [Morphological and biological properties of the Bacteroides fragilis bacteriophage phiA1]. PMID- 4145155 TI - [Occurrence of neuraminidase and acylneuraminat-lyase in Clostridium chauvoei (Clostridium feseri)]. PMID- 4145156 TI - [Taxonomic position of mobile, gram negative, strictly aerobic bacteria, isolated from pickling brine]. PMID- 4145157 TI - Naturally occurring competition between homologous polysaccharides and proteins of bacteria. PMID- 4145158 TI - Detection of orally toxic microbial metabolites in foods with bioassay systems. PMID- 4145159 TI - [Interferon sensitivity of various strains of influenza A2 viruses]. PMID- 4145160 TI - [Australia antigen in linen and underwear of hepatitis patients]. PMID- 4145161 TI - [Brain involvement in viral diseases. II. Experimental encephalitis of mice after infection with yellow fever virus strain 17 D and other brain lesions--a comparative analysis]. PMID- 4145162 TI - [Bacteriocin typing of Staphylococcus aureus]. PMID- 4145163 TI - [A mutant of Streptococcus pyogenes 56188 highly resistant to macrolide antibiotics and lincomycin]. PMID- 4145164 TI - [Immunoelectronmicroscopic localization of cell wall antigens in streptococci. I. Comparative demonstration of M protein of Streptococcus pyogenes with ferritin-, peroxidase- and ferrocen-labelled antibodies]. PMID- 4145165 TI - [Immunochemical studies on an antigen discovered in some enterobacteriaceae]. PMID- 4145166 TI - [Aerobic faecal flora of reptiles with special reference to the enterobacteria of snakes]. PMID- 4145167 TI - [Serological studies on bovine sera with antigens of mycobacteria, obtained by an electrophysical method]. PMID- 4145168 TI - [Special properties of Mycobacterium avis strains isolated from swine]. PMID- 4145169 TI - [Ecology of Mycobacterium intracellulare serotype Davis]. PMID- 4145170 TI - [Pigmented strains of the genus Nocardia. Influence of light on the pigment synthesis. Photochromogenic, negative-photochromogenic and scatochromogenic Nocardia species]. PMID- 4145171 TI - [Mycoplasma (Acholeplasma laidlawii) from cold blood cell cultures]. PMID- 4145172 TI - [Influence of thallium acetate on the growth of Acholeplasmataceae, Mycoplasmataceae, and some bacteria species]. PMID- 4145173 TI - [Suitability of the O-diphenol oxidase test using catechol for the differentiation of Cryptococcus neoformans]. PMID- 4145174 TI - A culture medium for the detection of deoxyribonuclease and phosphatase. PMID- 4145175 TI - [Sensitivity of Staphylococcus aureus and Staphylococcus epidermidis to thallium]. PMID- 4145176 TI - [Restorative therapy of patients with protracted depression]. PMID- 4145177 TI - A microsomal ATP-activated pyridine nucleotide transhydrogenase. PMID- 4145178 TI - Permeability of isolated mitochondria to oxaloacetate. PMID- 4145179 TI - An NAD(P) reductase derived from Chlorobium thiosulfatophilum: purification and some properties. PMID- 4145180 TI - Isolation and properties of chloroplast particles of Scenedesmus obliquus D 3 with high photochemical activity. PMID- 4145181 TI - Inhibition of yeast 1 -pyrroline-5-carboxylate dehydrogenase by common amino acids and the regulation of proline catabolism. PMID- 4145182 TI - The role of the pentose phosphate shunt in glucose induced insulin release: in vitro studies with 6-aminonicotinamide, methylene blue, NAD + , NADH, NADP + , NADPH and nicotinamide on isolated pancreatic rat islets. PMID- 4145183 TI - On the enzymology of the cornea. V. Further studies on the enzymes of keratoconus. PMID- 4145184 TI - Incontinence after piperacetazine treatment. PMID- 4145185 TI - The impact of number and type of models on claimed success rate and mood of adult alcoholics. PMID- 4145186 TI - Estimation of changes induced by drugs in cerebral energy-coupling processes in situ in the dog. PMID- 4145187 TI - Topical mosquito repellents. VI. Sulfonamides and quinoline-4-carboxylic acid derivatives. PMID- 4145188 TI - Lymphocyte depletion in the induction of chimerism in mice. PMID- 4145189 TI - Histocompatibility antigen systems and the control of the immune response: their relevance in disease susceptibility. PMID- 4145190 TI - Interaction of alpha and beta receptor blocking agents with platelet release and availability reaction induced by ADP, adrenaline and collagen. PMID- 4145191 TI - [Pathogenesis of intrahepatic cholestasis]. PMID- 4145192 TI - Equilibrium kinetic study of the catalytic mechanism of bovine liver glutamate dehydrogenase. PMID- 4145193 TI - Histamine and metabolites: their effects and interactions with convulsants on brain stem neurones. PMID- 4145194 TI - [Clinical trials of mefexamid (timodyne R) in psychiatric disorders]. PMID- 4145195 TI - Manipulation of environment to facilitate use of nematodes in biocontrol of insects. PMID- 4145196 TI - Thiosulfate- and sulfide-dependent pyridine nucleotide reduction and gluconeogenesis in intact Thiobacillus neapolitanus. AB - Nicotinamide adenine dinucleotide phosphate (reduced form) is formed more rapidly after the addition of thiosulfate to suspensions of intact Thiobacillus neapolitanus in the absence of CO(2) than nicotinamide adenine dinucleotide (reduced form). Measurement of acid-stable metabolites shows this phenomenon to be the result of rapid reoxidation of nicotinamide adenine dinucleotide (reduced form) by 3-phosphoglyceric acid and other oxidized intermediates, which are converted to triose and hexose phosphates, and that, in reality, the rate of nicotinamide adenine dinucleotide (oxidized form) reduction exceeds that of nicotinamide adenine dinucleotide phosphate (oxidized form) by approximately 4.5 fold. The overall rate of pyridine nucleotide reduction by thiosulfate (264 nmol per min per mg of protein) is in excess of that rate needed to sustain growth. Pyridine nucleotide reduction, adenosine triphosphate synthesis, and carbohydrate synthesis are prevented by the uncoupler m-Cl-Carbonylcyanide phenylhydrazone. Sodium amytal inhibits pyridine nucleotide reduction and carbohydrate synthesis are prevented by the uncoupler m-Cl-carbonylcyanide observations are reproduced when sulfide serves as the substrate. The rate of pyridine nucleotide anaerobic reduction with endogenous substrates or thiosulfate is less than 1% of the aerobic rate with thiosulfate. We conclude that the principal, if not the only, pathway of pyridine nucleotide reduction proceeds through an energy-dependent and amytal-sensitive step when either thiosulfate or sulfide is used as the substrate. PMID- 4145197 TI - Effect of methionine sulfoximine and methionine sulfone on glutamate synthesis in Klebsiella aerogenes. AB - At least two pathways exist in Klebsiella aerogenes for glutamate synthesis. A mutant blocked in one pathway due to the loss of glutamate dehydrogenase (gltD) does not require glutamate and has the same growth characteristics as the parent strain in most media; however, its growth is inhibited by the analogues methionine sulfoximine and methionine sulfone. Wild-type Klebsiella is resistant to 0.1 M methionine sulfoximine or methionine sulfone, whereas the gltD mutant is sensitive to 1 mM concentrations. Either glutamate or glutamine is effective in overcoming this inhibition. Activities of both glutamine synthetase and glutamate synthetase, two enzymes involved in the second pathway of glutamate synthesis, are inhibited by methionine sulfoximine and methionine sulfone. The primary effect of methionine sulfoximine appears to be the prevention of glutamine production necessary for subsequent glutamate synthesis via glutamate synthetase enzyme. PMID- 4145198 TI - Bacteremia in febrile children seen in a "walk-in" pediatric clinic. PMID- 4145199 TI - Childhood bacteremia. PMID- 4145200 TI - The pharmacokinetics and metabolism of Ko592 in man, dog and rat. PMID- 4145201 TI - Multidiscipline treatment of chronic pulmonary insufficiency. 1. Psychologic aspects of rehabilitation. PMID- 4145202 TI - [Value of Salbutamol in obstetrics]. PMID- 4145203 TI - [Stevens=Johnson syndrome]. PMID- 4145204 TI - [Immunodiffusion test for the determination of intrauterine infections]. PMID- 4145205 TI - The influence of different stabilizers on rubella virus resistance. PMID- 4145206 TI - [Characterization of a Streptococcus agalactiae bacteriocin]. PMID- 4145207 TI - [E. coli O 124:K 72 (B 17) as a cause of acute diarrhoeal diseases in adults and children]. PMID- 4145208 TI - [Secondary enrichment on Rappaport's medium for the isolation of salmonella from pig organs]. PMID- 4145209 TI - Morphology of bacteriophages used for typing of Shigella bacilli. PMID- 4145210 TI - R-factor transmission under lowered surface tension. PMID- 4145211 TI - [General immunity reactions in man following oral administration of acetone inactivated typhoid-enterovaccines. 3]. PMID- 4145212 TI - [Isolation of bacteriophages from lysogenic Nocardia asteroides strains]. PMID- 4145213 TI - [Morphological differentiation of some strains of Mycoplasma gallisepticum against different mycoplasma species on solid medium]. PMID- 4145214 TI - [Variants of Trichophyton rubrum]. PMID- 4145215 TI - [Experiments on the influence of metabolites and antimetabolites on the model of Trichomonas vaginalis. X. Experiments with amino-acids]. PMID- 4145216 TI - [Sensitivity of Yersinia pseudotuberculosis to antibiotics in vitro]. PMID- 4145217 TI - [A new salmonella species: S. kisii=6,7:d:1,2 sub genus I]. PMID- 4145218 TI - Arboviruses in Finland. IV. Isolation and characterization of Inkoo virus, a Finnish representative of the California group. PMID- 4145219 TI - The value of plasma gamma-glutamyl transpeptidase in the detection of hepatic metastases. PMID- 4145221 TI - Nicotinamide and adenosine nucleotide levels in Ascaris lumbricoides, Hymenolepis diminuta and Fasciola hepatica. PMID- 4145220 TI - Separation of thymus-derived and marrow-derived rat lymphocytes on glass bead columns. PMID- 4145223 TI - The acrylic resin tooth implant. 3. A continuing report. PMID- 4145222 TI - Attachment to the luteal plasma membranes: an early event in the action of luteinizing hormone. PMID- 4145224 TI - [Farber's lipogranulomatosis]. PMID- 4145225 TI - Ascorbate stimulation of tyrosine hydroxylase formation. PMID- 4145226 TI - A specific protease for pyridoxal enzymes. PMID- 4145227 TI - Behavioral differences between acute and chronic schizophrenics: course of psychosis, effects of institutionalization, or sampling biases? PMID- 4145228 TI - The adaptation of enzymes to pressure in abyssal and midwater fishes. PMID- 4145229 TI - Effect of antihistaminic drugs on hypoxic pulmonary hypertension. PMID- 4145230 TI - Hemodynamic effects of adrenergic stimulating and blocking agents in cardiogenic shock and low output state after myocardial infarction. PMID- 4145231 TI - Historical perspectives of coal workers' pneumoconiosis in the United States. PMID- 4145232 TI - Organic acid metabolism in Sclerotinia sclerotiorum. PMID- 4145233 TI - Methods of splinting permanent teeth which have been subjected to trauma. PMID- 4145234 TI - Comparison of adrenergic beta-receptor antagonists in angina pectoris. AB - The symptomatic, electrocardiographic, and circulatory effects of intravenous and oral preparations of propranolol, oxprenolol, and practolol were compared in 16 patients with uncomplicated angina pectoris precipitated by exertion. The method of study included treadmill exercise, double-blind assessment, single-blind analysis, with placebo control and randomized serial comparison of each drug in each patient. The doses used were selected to give the same near-maximum suppression of the heart rate response to exercise. The symptomatic, electrocardiographic, and circulatory response of each patient to both preparations of each of the three drugs was similar. Exercise tolerance was increased in two-thirds, unchanged in one-sixth, and significantly worsened in one-sixth of the studies. Electrocardiographic evidence of myocardial ischaemia was conspicuously reduced by all three drugs in most studies irrespective of their symptomatic effects. Though the exclusive choice of patients, the single dose design of the trial, and the treadmill method of assessment limit the general application of these results, they do clearly indicate that in doses that induce equal suppression of the exercise heart rate these three drugs have similar distinct anti-anginal activity. Their ancillary pharmacological properties are probably of little importance in this respect. Equally, the similarity in the symptomatic, circulatory, and electrocardiographic response to the intravenous and oral preparations suggests that metabolic breakdown products are probably of therapeutic importance only in so far as they antagonize beta receptor activity. PMID- 4145235 TI - Tumoral calcinosis in England. AB - Two cases of tumoral calcinosis are presented in patients living in England. The clinical and pathological features are described and attention is drawn to the need to consider exotic diseases in patients who have originated from or lived in the tropics.The cause of tumoral calcinosis is not known. It may be a metabolic disease of obscure aetiology but local trauma often appears to be a factor in its development. PMID- 4145237 TI - A simple technique for measuring the rate of milk secretion in the rat. PMID- 4145236 TI - Effect of diuretics on the secretion and reabsorption of ions in the kidney of marine teleosts. PMID- 4145238 TI - Thermoregulation in pythons. I. Effect of shelter, substrate type and posture on body temperature of the Australian carpet python, Morelia spilotes variegata. PMID- 4145239 TI - Hematologic parameters of the opossum (Didelphis virginiana). PMID- 4145240 TI - The effect of acclimation and acclimatization on the resting metabolic rate of the common redpoll. PMID- 4145241 TI - Physiological and ecological observations concerning the salt-secreting nasal glands of the roadrunner. PMID- 4145242 TI - The effects of altitude on oxygen-binding parameters of the blood of the iguanid lizards, Sceloporus jarrovi and Sceloporus occidentalis. PMID- 4145243 TI - Relaxation of catch in a molluscan smooth muscle. I. Effects of drugs which act on the adenyl cyclase system. PMID- 4145244 TI - Relaxation of catch in a molluscan smooth muscle. II. Effects of serotonin, dopamine and related compounds. PMID- 4145245 TI - Serosal and mucosal permeability coefficients for acetamide and thiourea in turtle (Testudo hermanni) jejunum. PMID- 4145246 TI - Adrenaline-induced hypercholesterolemia in the rainbow trout (Salmo gairdnerii Richardson): a separate study in male and female trout and the effect of adrenergic blocking agents. PMID- 4145247 TI - Studies on the possible regulation of plasma sodium by prolactin in amphibia. PMID- 4145248 TI - Comparative electrocardiography in lizards: effects of temperature and Gymnema sylvestre fractions. PMID- 4145249 TI - Body heat dissipation and conservation in two species of dolphins. PMID- 4145250 TI - Regulation of brain and eye temperatures by the bluefin tuna. PMID- 4145251 TI - Lactate oxidation in the upper-shore barnacle, Chthamalus depressus (Poli). PMID- 4145252 TI - Effects of hypophysectomy, pituitary autografts, prolactin, temperature and salinity of the medium on survival and natremia in the bullhead, Ictalurus melas. PMID- 4145253 TI - Action of isoprenaline and -blocking agents on stroke volume regulation. PMID- 4145254 TI - Interactions of membrane stabilizing drugs affecting human erythrocytes in vitro. PMID- 4145255 TI - Temperature-dependent supersensitivity to isoprenaline in mouse atria. PMID- 4145256 TI - Further studies on catecholamine synthesis in the spontaneously hypertensive rat: catecholamine synthesis in the central nervous system. PMID- 4145257 TI - Significance of cleft palate induced by chemicals in the rat and mouse. PMID- 4145258 TI - A survey on rats, rat fleas, house-flies and mosquitoes in village Rahimabad, Lucknow district. PMID- 4145259 TI - Performance of medical patient groups with and without brain damage on the Hovey (O) and Watson (Sc-O) MMPI Scales. PMID- 4145260 TI - Failure to validate an MMPI headache scale. PMID- 4145261 TI - Myelopathy after duck embryo rabies vaccine. PMID- 4145262 TI - [Mode of ulcerative colitis therapy and the symptom-free interval]. PMID- 4145263 TI - [Aspects of the therapy of threatened premature labor]. PMID- 4145264 TI - [Metabolic and humoral correlates of sleep]. PMID- 4145265 TI - Muscular disorders in some collagen diseases. A clinical, electromyographic and biopsy study. PMID- 4145266 TI - A survey of anesthetic choice among anesthesiologists. PMID- 4145267 TI - [NADP-specific glutamate dehydrogenase from yeast. 2. Several molecular parameters]. PMID- 4145268 TI - Paris Conference (1971): standardization in human cytogenetics. PMID- 4145269 TI - Practolol (Eraldin) eye drops as an ocular hypotensive agent. PMID- 4145270 TI - [Sequential replication of the pneumococcus chromosome]. PMID- 4145271 TI - Ring chromosome 7 with variable phenotypic expression. PMID- 4145272 TI - Incorporation of 32Pi orthophosphate into phospholipids of calf pineal slices in the presence and absence of neurotransmitters. PMID- 4145273 TI - Can we reduce the cost of medical education? PMID- 4145274 TI - Drug-induced arthropathy and necrosis of the femoral head. PMID- 4145276 TI - [Devices for transporting liquid wastes and wash water during space flight]. PMID- 4145275 TI - [Sanitary-health evaluation of the extraction method of regenerating water from atmospheric condensate]. PMID- 4145277 TI - [Effect of psychotropic drugs on human resistance to acceleration]. PMID- 4145278 TI - [Reliability of functioning of a biological component in a life-support system]. PMID- 4145279 TI - [Clinical experiences with the bronchotherapeutic agent Abiadin in infants and small children]. PMID- 4145280 TI - Hospital workers in dispute--harmonizing Europe. PMID- 4145281 TI - Calcium influx in active Aplysia neurones detected by injected aequorin. PMID- 4145282 TI - [Study of the nucleotides of bull cardiac mitochondria using liquid chromatography]. PMID- 4145283 TI - [Brain nitrogen metabolism during the growth of transplantable extracerebral sarcomas]. PMID- 4145284 TI - Cyclizing compounds. I. Tertiary N-(2-bromobenzyl)-N-haloalkylamines with adrenergic blocking action. PMID- 4145285 TI - Determination of sulphapyridine and its metabolites in biological materials after administration of salicylazosulphapyridine. PMID- 4145286 TI - Fluroxene and the penicillin lesson. PMID- 4145287 TI - The toxicity of fluroxene in animals and man. PMID- 4145288 TI - Binding of radioactivity from 14 C-labeled halothane in isolated perfused rat livers. PMID- 4145289 TI - Species differences and drug metabolism. PMID- 4145290 TI - Effect of calcium, sodium and potassium on adrenal tyrosine hydroxylase activity in vitro. PMID- 4145291 TI - Comparative effects of substituted phenothiazines and their free radicals on (Na =, K + )-activated adenosine triphosphatase. PMID- 4145292 TI - Influence of ischemia on the levels of reduced pyridine nucleotides in the pancreatic islets. PMID- 4145293 TI - Effect of stress on carrageenin inflammation in rats. PMID- 4145294 TI - Multiplication of Whataroa virus in mosquitoes. PMID- 4145295 TI - Host preferences of Deinocerites pseudes Dyar & Knab. PMID- 4145296 TI - Extension of the Midi-Mult to a college population. PMID- 4145297 TI - Suppression of tyrosine transaminase activity by rat liver ribosomes. PMID- 4145298 TI - Bovine thyroid cytosol glutamate dehydrogenase. PMID- 4145299 TI - Friend Leukemia Virus (FLV) activity in certain arthropods. I. Introduction, parameters and control measures necessary for evaluation of extrinsic incubation potential. PMID- 4145300 TI - Friend Leukemia Virus (FLV) activity in certain arthropods. II. Quantitative infectivity determinations. PMID- 4145301 TI - Host-tumour relationship. XXXI. Acid glycosaminoglycans in the plasma and in the ascitic fluid of rats during experimental tumour growth. PMID- 4145302 TI - The assessment and recording of measurements of growth of children: report of a small conference. PMID- 4145304 TI - To delegate. PMID- 4145303 TI - T cells and the immune response. PMID- 4145305 TI - Blood-feeding requirements of the mosquito: geographical variation in Aedes taeniorhynchus. AB - Wild poplulations of Aedes taeniorhynchus were polymorphic for the diets required for ovarian development. In Aedes taeniorhynchus populations from mangrove swamps, most females possessed the capacity to produce eggs on a blood-free diet. But where the grassy salt marsh was the mosquito's principal habitat,most females lacked this capacity. Both kinds of females could utiliZe a blood meal for egg production. PMID- 4145306 TI - [Growth and metabolism of the rabbit placenta in the last third of pregnancy]. PMID- 4145307 TI - Ultrastructural aspects of the role of the media-smooth muscle cells in arteriosclerosis of man and animals. PMID- 4145308 TI - Pulmonary lesions in systemic necrotizing angiitis. PMID- 4145309 TI - Histopathological findings of the lung in collagen diseases--especially on their differential diagnosis. PMID- 4145310 TI - Fluid intake behavior in patients with spinal-cord injury: prediction and modification. PMID- 4145311 TI - [Synthesis of N-benzyl-aminocarbonic acids and their derivatives]. PMID- 4145312 TI - [Pharmacological studies on a substance with antitussive and respiration stimulating properties]. PMID- 4145313 TI - Polyarteritis nodosa in an infant. A problem of diagnosis. PMID- 4145314 TI - Breakage prior to entry of donor DNA in Pneumococcus transformation. PMID- 4145315 TI - [Herpes gestationis]. PMID- 4145316 TI - Influence of methylxanthines and local anaesthetics on the metabolism of muscle and associated changes in mitochondrial morphology. PMID- 4145317 TI - Low speed preparation of microsomes: a comparative study. PMID- 4145318 TI - Pharmacological studies with tiprenolol and propranolol in man. PMID- 4145319 TI - The anticonvulsant effect of carbonic anhydrase inhibitors in mice--a noradrenergic mechanism of action. PMID- 4145321 TI - Influence of N-alkyl substitution on antagonism at 1 - and 2 -receptor sites. PMID- 4145320 TI - Effect of prostaglandin E 2 on central and peripheral catecholamine neurons. PMID- 4145322 TI - Phenylalanine hydroxylase activity in rat liver. PMID- 4145323 TI - Influence of high cholesterol diet on some liver enzymes. PMID- 4145324 TI - Studies on glutamine synthetase from Escherichia coli. Formation of pyrrolidone carboxylate and inhibition by methionine sulfoximine. PMID- 4145325 TI - Effects of oxidation of tryptophan residues in thioredoxin from Escherichia coli by N-bromosuccinimide. PMID- 4145326 TI - Synthesis of cerebronic acid from lignoceric acid by rat brain preparation. Some properties and distribution of the -hydroxylation system. PMID- 4145327 TI - Inhibition of rat liver acetyl coenzyme A carboxylase by N 6 ,O 2' -dibutyryl cyclic adenosine 3':5'-monophosphate in vitro. PMID- 4145328 TI - Relative usefulness of three forms of the Mini-Mult with college students. PMID- 4145329 TI - The Wechsler in personality assessment: object assembly subtest as predictive of bodily concerns. PMID- 4145330 TI - Beta adrenergic blockade theory of bronchial asthma. PMID- 4145331 TI - [The activity of various cerebral nitrogen metabolism enzymes in hypothermia]. PMID- 4145332 TI - The effects of an alpha adrenergic blocker on thyrocalcitonin activity in male and female rats. PMID- 4145333 TI - Skin disorders of the newborn. PMID- 4145334 TI - [Successful treatment of Candida septicaemia and interstitial pneumonia]. PMID- 4145336 TI - The dearalkylation of fomocaine isomers by microsomal monooxygenase system of rabbit liver. PMID- 4145335 TI - [Inhibition of enzymes of the internal mitochondrial membrane by benzbromarone]. PMID- 4145337 TI - Dissociated thymus and bone marrow cells: synergism in graft versus host reaction. PMID- 4145338 TI - Separation of rauwolfia alkaloids by thin-layer chromatography. PMID- 4145339 TI - Role identity development of the child health associate. PMID- 4145340 TI - A rapid slide-agglutination method for typing pneumococci by means of specific antibody adsorbed to protein A-containing staphylococci. PMID- 4145341 TI - [Oxidative processes in different regions of the heart following experimental myocardial infarctions]. PMID- 4145342 TI - Reversible metabolic stimulation of polymorphonuclear leukocytes and macrophages by concanavalin A. PMID- 4145343 TI - Turning behavior of mice with unilateral 6-hydroxydopamine lesions in the striatum: effects of apomorphine, L-DOPA, amanthadine, amphetamine and other psychomotor stimulants. PMID- 4145344 TI - Decreased tyrosine hydroxylase activity in the adrenal gland of adult rats that were handled in infancy. PMID- 4145345 TI - Energetic aspects of nerve conduction: the relationships between heat production, electrical activity and metabolism. PMID- 4145346 TI - Some clinically important interactions of psychotropic drugs. PMID- 4145347 TI - Effects "in vitro" of some cardiovascular drugs and other agents on human platelet aggregation. PMID- 4145350 TI - Experiments in the 5H-dibenzo[a,d]cycloheptene series. Synthesis and pharmacology of some 5-subsitiuted 6,7,8,9-tetrahydro-5H-benzocycloheptenes. PMID- 4145349 TI - [The effects of coronary actve drugs on membrane metabolism and permeability]. PMID- 4145348 TI - Management of post-traumatic pain syndromes: report of 113 cases. PMID- 4145351 TI - A conformational transition of the oligomer of glutamate dehydrogenase induced by half-saturation with NAD + or NADP + . PMID- 4145353 TI - Phenylalanine hydroxylase activity in foetal hepatic organ culture. PMID- 4145352 TI - Reversible inactivation of the nitrate reductase of Chlorella vulgaris Beijerinck. PMID- 4145354 TI - [Neuroendocrine relations]. PMID- 4145355 TI - [Development of steroid endocrinology]. PMID- 4145357 TI - [Preparatory metabolic reflexes]. PMID- 4145356 TI - [Peripheral factors in the action of hormones]. PMID- 4145358 TI - Elevation of hepatic tyrosine 2-oxoglutarate aminotransferase in rats by 4 pentynoic acid, a hypoglycemic agent. PMID- 4145359 TI - Interaction between -adrenergic stimulant and phosphodiesterase inhibiting drugs on the bronchial muscle. PMID- 4145360 TI - Feeding elicited in sheep by intrahypothalamic injections of PGE 1 . PMID- 4145361 TI - Sex difference in susceptibility of mice to pneumococcus. PMID- 4145362 TI - Allogeneic stimulation of anti-hapten response in mice. PMID- 4145363 TI - Comparison between the personalities of LSD users and nonusers as measured by the Minnesota Multiphasic Personality Inventory. PMID- 4145364 TI - Homologous and heterologous hematopoietic stem cells. PMID- 4145365 TI - [Long-term treatment of angia pectoris with pindolol]. PMID- 4145366 TI - [Influence of an angiolytic drug on psychological functions of the aged person]. PMID- 4145367 TI - Physiological studies on Phymatotrichum omnivorum. 3. Enzymes of glucose catabolism. PMID- 4145368 TI - Education and guidance of the physician's assistant. PMID- 4145369 TI - Thymus transplantation. Permanent reconstitution of cellular immunity in a patient with sex-linked combined immunodeficiency. PMID- 4145370 TI - Amine turnover changes in the tubero-infundibular dopamine (DA) neurons in immature rats injected with PMS. PMID- 4145371 TI - [Report on the Caries Symposium at Vienna]. PMID- 4145372 TI - The origin of the hypertensive effect of arecoline in rats. PMID- 4145373 TI - [Family planning]. PMID- 4145374 TI - Effect of age upon guanyl cyclase, adenyl cyclase, and cyclic nucleotide phosphodiesterases in rats. PMID- 4145375 TI - Effect of 10 undecen 1-YL thiopseudourea iodide (AHR-1911) on rat arterial pressure and capillary permeability. PMID- 4145376 TI - [Pelvic sympathalgias of a traumatic and inflammatory nature]. PMID- 4145377 TI - Kinetic and thermodynamic aspects of the mechanism of general anesthesia in a model system of firefly luminescence in vitro. PMID- 4145378 TI - The effects of forane and fluroxene on mitochondrial respiration: correlation with lipid solubility and in-vivo potency. PMID- 4145379 TI - Modification of fluroxene toxicity. PMID- 4145380 TI - Review and evaluation of 6-hydroxy-dopamine (6-HD): chemical sympathectomy for the treatment of glaucoma. PMID- 4145381 TI - On the activity of glutamine synthetase in the red blood cells. PMID- 4145382 TI - Neurohumoral regulation of adenylate cyclase activity in rat striatum. PMID- 4145383 TI - Huntington's disease masquerading as chronic schizophrenia. PMID- 4145384 TI - [Discriminative study of the effect of a psychotropic drug by use of B.P.R.S. cards]. PMID- 4145385 TI - An analysis of the B-adrenergic action of oxyfedrine. PMID- 4145386 TI - Induction of hypotension during surgery. PMID- 4145387 TI - Regulation of the antibody response to type 3 pneumococcal polysaccharide. I. Nature of regulatory cells. AB - The effect of treatment with antilymphocyte serum (ALS) on the magnitude of the plaque-forming cell (PFC) response to Type III pneumococcal polysaccharide (SSS III) was assessed in athymic nude mice and thymus-bearing littermate controls. Without ALS treatment, the PFC response was slightly higher in nude than in control mice. Treatment with ALS had no effect on the response of nude mice; however, considerable enhancement was noted in thymus-bearing controls. Such enhancement was ALS dose-dependent and demonstrable under conditions in which there was substantial inactivation of thymic-derived "helper" cells required for an antibody response to erythrocyte antigens. These findings suggest that amplifier and suppressor cells, which have been reported to regulate the magnitude of the antibody response to SSS-III, represent populations of thymic derived cells (T cells) that are not present in nude mice. The activities of "helper" T cells and regulatory T cells appear to be independent of one another and mediated by separate subpopulations of T cells. PMID- 4145388 TI - Arboviruses in Hungary. PMID- 4145389 TI - Crowd hysteria in a junior high school. PMID- 4145390 TI - Storage and transplantation of bone marrow in the treatment of malignant diseases. PMID- 4145391 TI - [Frequency of rickets-like bone lesions during anticonvulsive therapy]. PMID- 4145392 TI - [Report on the II International Symposium on the lacrimal system]. PMID- 4145393 TI - [Drug therapy of hypertension]. PMID- 4145394 TI - [Testosterone metabolism in hypogonadism]. PMID- 4145395 TI - [Attempt at classification of testicular anomalies]. PMID- 4145396 TI - [Change in the gonadotropic function in rats during the use of the new Soviet contraceptive megestranol]. PMID- 4145397 TI - [Problem of vascular reactivity in the mechanism of regulatory and pharmacological effects on the blood circulation]. PMID- 4145399 TI - Patient attitudes toward physician's assistants. AB - A study was conducted in urban Los Angeles to assess patient acceptance of the use of physician's assistants. Data collection was facilitated by the development of an attitude scale and responses were analyzed to determine differences between various socioeconomic stratifications. With a few exceptions, acceptance was highest among non-married middle-class respondents who have had some exposure to college. As to the perceived complexity of procedures a physician's assistant might perform, 91 percent of all respondents would not object to injections administered by a physician's assistant, but this tolerance diminishes to 34 percent in the case of first examination of a patient by a physician's assistant if there appeared to be a serious head injury. PMID- 4145398 TI - Pheochromocytoma. Tumor localization and surgical management. AB - Recent experience with five cases of pheochromocytoma is the basis for this report. Pharmacological blockade is to be started with phenoxybenzamine before angiographic studies. Arteriography is the preferred localization technique, particularly when combined with bone-subtraction films. Anesthetic management requires special attention to premedication, close monitoring of cardiac rhythm, arterial and central venous pressure, and judicious administration of alpha and beta blockers. Methoxyflurane is no longer the anesthetic agent of choice because of possible nephrotoxicity. Multiple tumors are common. Wide surgical exposure with systematic palpation of autonomic ganglia must be carried out. Manipulation of the tumor does raise arterial blood pressure in spite of adequate preoperative blockade. The alpha blockade prevents the sudden and dangerous vascular collapse which used to be seen after removal of the tumor. PMID- 4145400 TI - Intraaortic balloon pumping for control of recurrent myocardial ischemia. PMID- 4145401 TI - Treatment of fever in burned children. A therapeutic program. PMID- 4145402 TI - Treatment of sedative drug overdose. PMID- 4145403 TI - Effects of mepyramine, promethazine, and hydrocortisone on paracetamol-induced hepatic necrosis in the rat. PMID- 4145404 TI - Variation of hexokinase insoenzyme pattern in Ehrlich ascites-tumor cells in relation to the utilization of glucose in the cells. PMID- 4145405 TI - Regulatory function of malate dehydrogenase isoenzymes in the cotyledons of mung bean. PMID- 4145406 TI - Comparative studies on glutamine, serine, and glycine metabolisms in ureotelic and uricotelic animals. PMID- 4145407 TI - Stability of messenger RNA's for microsomal NADPH-cytochrome c reductase and cytochrome b 5 in the livers of normal and phenobarbital-treated rats. PMID- 4145408 TI - A photorepressible isozyme of malic enzyme in Euglena gracilis strain Z. PMID- 4145409 TI - [Properties of the mitochondrial electron transport system of Acanthamoeba castellanii Neff. I. Effect of inhibitors on various acceptor systems tested by means of a modified Thunberg technic]. PMID- 4145410 TI - [Properties of the mitochondrial electron transport system of Acanthamoeba castellanii Neff. II. Purification and properties of the NADH-acceptor oxidoreductase of the electron transport system]. PMID- 4145411 TI - [Shock--continually a current problem]. PMID- 4145412 TI - [Trial of Terbutaline administered orally in the treatment of asthma]. PMID- 4145413 TI - [Effects of a beta-adrenergic stimulant: Salbutamol, on spontaneous or induced bronchial obstruction in asthma]. PMID- 4145414 TI - [2 cases of allergic complications caused by Hymenoptera bites]. PMID- 4145415 TI - [Follow-up treatment of osteosyntheses]. PMID- 4145416 TI - Pharmacology of the central nervous system. PMID- 4145417 TI - Tests of an alternative explanation of data supporting the R scale of the MMPI as a measure of acquiescence. PMID- 4145418 TI - Vasopressin and cerebral tiredness. PMID- 4145419 TI - [Study on the hypothalamic vascularization in aged rats]. PMID- 4145420 TI - [Adverse reactions of the topical application of local anesthetics, antibiotics and vasoconstrictors in the oral region]. PMID- 4145421 TI - Meeting in Minneapolis. PMID- 4145422 TI - Neuroamine-derived alkaloids: a possible common denominator in alcoholism and related drug dependencies. PMID- 4145423 TI - Effect of ethanol on biosynthesis of dopamine. PMID- 4145424 TI - A possible role of central noradrenergic neurons in withdrawal states from alcohol. PMID- 4145425 TI - The feeding response of the larva of the Egyptian cotton leafworm, Spodoptera littoralis boisd., to sugars and related compounds. 3. Biochemical and enzymological aspects of sucrose consumption. PMID- 4145426 TI - Oxygen consumption of the larvae of the lobster Panulirus interruptus (Randall) and the crab Cancer productus Randall. PMID- 4145427 TI - A comparison of the effects of mammalian TSH on the thyroid glands of the teleost Galeichthys felis and the elasmobranch Dasyatis sabina. PMID- 4145428 TI - Immunoglobulin synthesis in fetal sharks. PMID- 4145429 TI - Variation in the yield and composition of milk throughout lactation in the guinea pig (Cavia porcellus). PMID- 4145430 TI - Effects of ouabain and high K + on respiration of turtle brain and urinary bladder in vitro. PMID- 4145431 TI - Observations on the relationship between the food consumption and metabolic rate of Blennius pholis L. PMID- 4145432 TI - Response of toad bladder to prolactin. PMID- 4145433 TI - Inhibition of vasopressin-stimulated water transport across the isolated toad bladder. PMID- 4145434 TI - Contracture tension in rat vas deferens and ileal smooth muscle and its modification by external calcium and the tonicity of the medium. PMID- 4145435 TI - Effect of acetazolamide on some hematological parameters and ocular oxygen concentration in rainbow trout. PMID- 4145436 TI - The percentage of passively contracted fibres in rigor skeletal muscles from different species. PMID- 4145437 TI - Body temperature regulation in the brown-necked raven (Corvus corax ruficollis). I. Metabolic rate, evaporative water loss and body temperature of the raven exposed to heat stress. PMID- 4145438 TI - Body temperature regulation in the brown-necked raven (Corvus corax ruficollis). II. Thermal changes in the plumage of ravens exposed to solar radiation. PMID- 4145439 TI - Responses of Merriam's kangaroo rats, Dipodomys merriami, to various levels of carbon dioxide concentration. PMID- 4145441 TI - Carcinoid-like tumours in the pseudobranch of Gadus morhua L. PMID- 4145440 TI - Erythrocytic enzymes and glycolytic intermediates in the normal bovine and in bovine erythropoietic porphyria. PMID- 4145443 TI - Metabolized energy of the big brown bat Eptesicus fuscus (Chiroptera). PMID- 4145442 TI - The effects of cold and glucagon on lipolysis, glycogenolysis and oxygen consumption in young chicks. PMID- 4145444 TI - Temperature and the Galapagos marine iguana--insights into reptilian thermoregulation. PMID- 4145445 TI - Comparative studies on the swimming behaviour of the blind cave fish and the goldfish. PMID- 4145446 TI - Studies on water and ion movements in the isolated urinary bladder of selected freshwater, marine and euryhaline teleosts. PMID- 4145447 TI - Influence of glucagon and neurohypophysial hormones on plasma free fatty acid levels in the pigeon. PMID- 4145448 TI - Intestinal water absorption in Tilapia mossambica. I. Water movement in everted sacs of intestine bathed on both surfaces by identifcal ringer solution. PMID- 4145449 TI - Calcium restriction and intestinal calcium-binding protein in the laying fowl. PMID- 4145450 TI - Uterine calcium-binding protein in the laying fowl. PMID- 4145451 TI - Suppression of the avian reticuloendothelial system and enhancement of a Plasmodium lophurae infection in diethylstilbestrol treated chickens. PMID- 4145452 TI - [Effect of Mg 2+ ion on growth of tadpoles of Discoglossus pictus (Otth) and on the in vitro protein synthesizing capacity of their microsomes]. PMID- 4145453 TI - Lysosomal acid hydrolases in the chloragogen cells of earthworms. PMID- 4145454 TI - Ion and water turnover in the fresh-water elasmobranch Potamotrygon sp. PMID- 4145455 TI - Regulations of aerobic fermentation in protozoans. II. Allosteric inhibition of the malic enzyme. PMID- 4145457 TI - Transhydrogenase-induced responses of carotenoids, bacteriochlorophyll and penetrating anions in Rhodospirillum rubrum chromatophores. PMID- 4145456 TI - Thermostability of some mitochondrial enzymes of lower vertebrates. II. Fresh water teleosts. PMID- 4145458 TI - The influence of adrenergic activation and blockade on the motility of the circular and longitudinal muscle layers of the rabbit oviduct in vitro. PMID- 4145459 TI - [Study of the work capacity of students]. PMID- 4145460 TI - Manipulation of immunologically reactive cell populations in vitro. Outline of an approach to specific immunotherapy of cancer. PMID- 4145461 TI - Adoptive tumor immunotherapy in mice as an adjunct to whole-body x-irradiation and chemotherapy. A review. PMID- 4145462 TI - Destruction of tumor as an "innocent bystander" in an immune response specifically directed against nontumor antigens. PMID- 4145463 TI - Mnemonic organization in young nonpsychotic schizophrenics. PMID- 4145464 TI - Missing and rudimentary upper lateral incisors. A statistical survey. PMID- 4145465 TI - Caries experience of 11-17-year-old childred. A mixed longitudinal epidemiological study. PMID- 4145466 TI - [Vadilex in otorhinolaryngologic diseases]. PMID- 4145467 TI - [Use of beta-adrenolytic agent in the treatment of angina pectoris]. PMID- 4145468 TI - Involvement of a hydrophobic site in the inhibition of the microsomal p hydroxylation of aniline by alcohols. PMID- 4145469 TI - The occurrence and functional significance of dopamine in some peripheral adrenergic nerves of the rat. PMID- 4145471 TI - The effects of multiple anaesthetics on the livers of rats subjected to microsomal enzyme induction. A preliminary report. PMID- 4145470 TI - N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans. PMID- 4145472 TI - Observations on freshly isolated and accurately identified spermatogenic cells of the rat. Early effects of heat and short-time experimental cryptorchidism. PMID- 4145473 TI - [Treatment of leg diseases in general practic using medigel]. PMID- 4145474 TI - The secondary immune response of the bovine lymph node to the infectious bovine rhinotracheitis--infectious pustular vulvovaginitis virus. PMID- 4145475 TI - [Experimental study on the adsorption of poliomyelitis-vaccination virus type 2, during filtration through millipore-membrane filters]. PMID- 4145476 TI - [Cultivation of staphylococci for the collection of larger amounts of enterotoxins]. PMID- 4145477 TI - [Comparison of various cultivation technics for the determination of enterotoxins in staphylococcus strains]. PMID- 4145478 TI - Growth-inhibition of micrococcus lysodeikticus by anti-plasma-membrane antibodies. PMID- 4145479 TI - [Infant enteritis due to coli. 3. Immune properties of enteropathogenic Coli-O strains]. PMID- 4145480 TI - [Infant enteritis due to Coli. IV. Enteropathogenic and normal Coli strains]. PMID- 4145481 TI - [Bacteriokinases and their physiological importance. II. Studies on Coli strains]. PMID- 4145482 TI - [Immunology of enteritides caused by enteropathogenic E. coli]. PMID- 4145483 TI - [Studies on the classification of Salmonella R forms. 6. Studies on Salmonella typhimurium mutants]. PMID- 4145484 TI - [Antigenic relation between the Citrobacter "Pecs" strain and the "D" group Salmonellae]. PMID- 4145485 TI - Induction of interferon in mice by detoxicated O-antigens of Salmonella typhi and Serratia marcescens. PMID- 4145486 TI - Snakes as reservoirs of Arizona and Salmonella. PMID- 4145487 TI - Morphological and biochemical studies of 6 strains of Plesiomonas shigelloides isolated from clinical sources. PMID- 4145488 TI - [Isolation of two bacteroides fragilis phages from sewage and detection of lysogenic B. fragilis strains]. PMID- 4145489 TI - [Bacterial kininases and their physiological importance. I. Studies on Clostridia strains]. PMID- 4145490 TI - [Enzyme induction and metabolic regulation in mycobacteria. Hydrolysis of aliphatic amides in rapidly growing mycobacteria]. PMID- 4145491 TI - On the incidence of mycoplasma contamination in cell cultures. PMID- 4145492 TI - [The "Pril-Mannite-Agar" in Salmonella diagnostics]. PMID- 4145493 TI - [Experimental studies of the transmission of rabies virus infection among mice under natural conditions]. PMID- 4145494 TI - [Infantile enteritis due to Escherichia coli. V. Studies on the isolated rabbit intestine with total and partial antigens of normal and enteropathogenic E. Coli]. PMID- 4145495 TI - [Oral immunization with non-viable micro-organisms or their antigens. 15. Immunogenicity from fractions of S. typhi murium bacteria in the mouse protection test]. PMID- 4145496 TI - Transformation of pathogenic Shigella-like E. Coli strains into attenuated strains for preventive and therapeutical purposes. PMID- 4145497 TI - [Immunreaction in swine fetuses. 1. Application of gnotobiotic methods to experimental immunological studies in fetuses]. PMID- 4145498 TI - [Immunreaction in swine fetuses. 2. Studies on the presence of immunoglobulins and antibodies in untreated fetuses]. PMID- 4145500 TI - [Culture of Clostridum butyricum, strain M 55. 3. Culture media containing asparagin]. PMID- 4145499 TI - [Immunreaction in swine fetuses. 3. Stimulation of immunoglobulin synthesis by vaccination]. PMID- 4145501 TI - [Studies on the behavior of 2-mercaptoethanol-resistant antibodies following vaccination against cholera in a non-endemic area]. PMID- 4145502 TI - [Hay as a nutrient substratum for Cryptococcus neoformans]. PMID- 4145503 TI - A latent nitrate reductase from a thermophilic alga. PMID- 4145504 TI - Effects of glutamine on the two catalytic activities of glutamine synthetase in cultured mouse cells strain L. PMID- 4145505 TI - [Transplantation of cells from hematopoietic organs in hypersplenic mice]. PMID- 4145506 TI - Effects of catecholamines upon serum FFA levels in normal and diabetic goldfish, Carassius auratus L. PMID- 4145507 TI - Comparison of diurnal variations in plasma glucose, cholesterol, triglyceride, insulin and in liver glycogen in younger and older chicks (Gallus domesticus). PMID- 4145508 TI - Serum protein changes during metamorphosis in Ambystoma tigrinum. PMID- 4145509 TI - The effect of parathion on crustacean skeletal muscle. I. The mechanical threshold and dependence on Ca 2+ ions. PMID- 4145510 TI - The effect of parathion on crustacean skeletal muscle. II. Disruption of excitation-contraction coupling. PMID- 4145511 TI - Metabolic rate in relation to body size and environmental oxygen concentration in two species of xanthid crabs. PMID- 4145512 TI - The influence of thyroxine and environmental temperature on the specific activity of hepatic malic enzyme in young male chicks. PMID- 4145513 TI - The influence of environmental temperature on the fatty acid composition of liver and carcase lipids in the young male chick fed on equalized and ad lib intakes. PMID- 4145514 TI - Changes in lactate dehydrogenase zymograms from forelimb and tail regenerates of two species of salamander. PMID- 4145515 TI - Functional development of the bovine exocrine pancreas. PMID- 4145516 TI - Changes in epidermal DNA, protein and protein synthesis during the molt cycle of the crayfish Orconectes sanborni (Faxon). PMID- 4145517 TI - The ecological significance of thermoregulatory responses to heat stress shown by two populations of an Australian murid, Rattus fuscipes. PMID- 4145518 TI - The effects of repeated desiccation and rehydration on lipid and haemoglobin concentrations in fasting Ornithodoros concanensis (Acarina: Argasidae). PMID- 4145519 TI - Nitrogen excretion in the larvae of a land-nesting frog (Leptodactylus bufonius). PMID- 4145520 TI - The effect of prolactin on water influx in isolated gills of the goldfish, Carassius auratus L. PMID- 4145522 TI - Seasonal carbon dioxide and oxygen concentrations in the dens of hibernating mammals (Sciuridae). PMID- 4145521 TI - Effects of ambient temperature on the resting metabolic rate of cold- and heat acclimated Macaca mulatta. PMID- 4145523 TI - Electrophoresis of the hemoglobin of three animals in the hibernating and non hibernating state. PMID- 4145524 TI - Blood volume regulation in dehydrated rodents: plasma colloid osmotic pressure, total osmotic pressure and electrolytes. PMID- 4145525 TI - Cyclical fluctuations in the levels of blood calcium, pH and pCO 2 in Japanese quail. PMID- 4145526 TI - Renal physiology of cold exposed and uninephrectomized golden hamsters. PMID- 4145527 TI - Temperature effect on parr-smolt transformation in steelhead trout (Salmo gairdneri) as measured by gill sodium-potassium stimulated adenosine triphosphatase. PMID- 4145528 TI - Propionylcholinesterase in the nervous ganglia of the fresh-water pulmonate mollusc Lymnaea stagnalis. PMID- 4145529 TI - Sodium balance of the Red River pupfish Cyprinodon rubrofluviatilis. PMID- 4145530 TI - Effect of simultaneous exposure to differences in photoperiod and temperature on the seasonal molt and reproductive system of the white-footed mouse, Peromyscus leucopus. PMID- 4145531 TI - Glycosidases in the spermatophores of the giant octopus, Octopus dofleini Martini. PMID- 4145532 TI - Mechanical activity of the gastrocnemius muscle in the albino rat under water deprivation at different temperatures. PMID- 4145533 TI - Psychodynamics of dental emergencies. PMID- 4145534 TI - [Effect of light on the induction by ammonia of NADP-glutamate dehydrogenase in Chlorella]. PMID- 4145535 TI - Analysis of the role of H-2 genotypic and phenotypic differences in the spleen colony formation and lymphatic follicle repopulation by bone marrow cells. PMID- 4145536 TI - Blood lymphocyte nuclei activation and skin allograft rejection in mice. PMID- 4145537 TI - Reduced migration capacity in vitro of peritoneal exudate cells from adult thymectomized, irradiated and bone marrow-protected rats. PMID- 4145538 TI - The next step. PMID- 4145539 TI - Effects of 17 beta-estradiol on the distribution and activity of some oxydative enzymes of uterine and cervical epithelium in neonatal mice. PMID- 4145540 TI - Biosynthesis and storage of catecholamines in pheochromocytoma and neuroblastoma cells. PMID- 4145541 TI - [Comparison of the effects of practolol and propranolol on systemic and regional circulation in the patient with heart disease]. PMID- 4145542 TI - [Study of the effects of intravenous administration of a synthetic adrenaline derivative of 1-(4-oxy-phenyl)-1-oxy-2-N-butylamino-ethane sulphate in central and peripheral vascular diseases]. PMID- 4145543 TI - Gifts from the sea. PMID- 4145544 TI - [Changes in proteolytic activity of the gastric juice in experimental ulcer in dogs]. PMID- 4145545 TI - American Academy of Pediatrics Committee Statement. The ten-state nutrition survey: a pediatric perspective. PMID- 4145546 TI - Exercise testing and training in coronary heart disease. PMID- 4145547 TI - [Experience with the Tavegil therapy of chronic pruritic dermatoses]. PMID- 4145548 TI - Grafting of fetal thymus and hematopoietic tissue in infants with immune deficiency syndromes. PMID- 4145549 TI - Immune response in aged mice. Change of cell-mediated immunity with aging. PMID- 4145550 TI - Synergistic effect of antilymphocyte serum and the graft-versus-host reaction on murine skin allograft survival. PMID- 4145551 TI - Inhibition of the graft-versus-host reaction. II. Prevention of acute graft versus-host mortality by Fab fragments of antilymphocyte globulin. PMID- 4145552 TI - [Synthesis of nicotinamide-adenine dinucleotide phosphate and its regulation in rat tissues on the administration of nicotinic acid]. PMID- 4145553 TI - [Effect of serotonin on energy processes in tumors and bone marrow]. PMID- 4145554 TI - [Characteristics of nitrogen metabolism in the rat brain under the action of a low frequency impulse electromagnetic field]. PMID- 4145555 TI - [Transmission and inhibition of extrachromosomal drug-resistance factors in the gastrointestinal flora]. PMID- 4145556 TI - [Development of penicillin resistance and its prevention]. PMID- 4145557 TI - [Occurrence of drug-resistant bacteria in the feces of ruminants]. PMID- 4145558 TI - [Staphylococcal penicillinase activity in the cow]. PMID- 4145559 TI - [Effect of levallorphen, a morphine derivative, on the transmission of drug resistance factors]. PMID- 4145560 TI - [Evaluation of automatic data processing in routine diagnosis]. PMID- 4145561 TI - [Projects for the use of automatic data processing in routine microbiological diagnosis]. PMID- 4145562 TI - [Automation technics in microbial titrations]. PMID- 4145563 TI - [Current problems in the diagnosis of mycoses]. PMID- 4145564 TI - [New methods for simplification of the multi "colored series"]. PMID- 4145565 TI - [Methods for the detection of mycoplasma infections]. PMID- 4145566 TI - [Nonserological methods for the identification of mycoplasmatales]. PMID- 4145567 TI - [A new method for the evaluation of diagnostic schemes]. PMID- 4145568 TI - [Parallel multi=analysis: a first step towards automatic screening of microbial metabolism]. PMID- 4145569 TI - [Continous determination of the resistance spectrum using electronic data processing in the routine bacteriological diagnosis. 3-year experience]. PMID- 4145570 TI - [Problems in the standardization of Australia-SH-antigen determinations]. PMID- 4145571 TI - [Australia antigen and transfusion hepatitis. A prospective study on the frequency and prevention of transfusion hepatitis]. PMID- 4145572 TI - [Serodiagnosis of rubella during pregnancy and of rubella embryopathy in the newborn infant]. PMID- 4145573 TI - [Microbiological diagnosis of nocardia infections]. PMID- 4145574 TI - [Characterization of dermatophytes using their group-specific reactions against antibiotics]. PMID- 4145576 TI - [Advantage and disadvantage of immunizations]. PMID- 4145575 TI - [Diagnostic possibilities in the detection of aflatoxin poisoning]. PMID- 4145577 TI - [Problems in the immunization against rubella]. PMID- 4145578 TI - [Measles vaccination]. PMID- 4145579 TI - [Tryptophan excretion and metabolic interlock in Escherichia coli K 12]. PMID- 4145580 TI - [Biosynthesis of 4-aminobenzoic acid in Aerobacter aerogenes]. PMID- 4145581 TI - [Regulation of aromatic amino acid biosynthesis in streptomycetes]. PMID- 4145582 TI - [Intermediary products of riboflavin biosynthesis]. PMID- 4145583 TI - [Genetic studies on riboflavin deficiency mutants in saccharomyces cerevisiae]. PMID- 4145584 TI - [Properties of mutated threonine deaminase in Escherichia coli]. PMID- 4145585 TI - [Isoleucine biosynthesis in mutants for arthrobacter following varying growth conditions]. PMID- 4145586 TI - [Induction of dehydrogenase activity for branched amino acids in Bacillus subtilis (brief report)]. PMID- 4145587 TI - [Biosynthesis of sideramines in fungi. Stereo-specificity of the mevalonic acid dehydration (brief report)]. PMID- 4145588 TI - [Biosynthesis of nonactin (brief report)]. PMID- 4145589 TI - [Biosynthesis of bacitracin]. PMID- 4145590 TI - [The effect of L-2,5-dihydrophenylalanine]. PMID- 4145591 TI - [Regulation of the amino acid uptake in Streptomyces hydrogenans]. PMID- 4145592 TI - [Conjugation in star-forming soil bacteria]. PMID- 4145593 TI - [Readiness for gene transfer in the Rhizobium lupini conjugation (brief report)]. PMID- 4145594 TI - [The cell fusion in star-forming bacteria (brief report)]. PMID- 4145595 TI - [Adsorption mechanism of an incomplete bacteriophage on Rhizobium lupini (brief report)]. PMID- 4145596 TI - [Fine structure and biochemistry of flagellae from star-forming bacteria]. PMID- 4145597 TI - [New results in the localization of protein and DNA in poxviruses (brief report)]. PMID- 4145598 TI - [Formation of complex DNA structures of the colicin factor E 1 in temperature sensitive replication mutants of E. coli]. PMID- 4145599 TI - [Enrichment and characterization of Streptococcus agalactiae bacteriocins (brief report)]. PMID- 4145600 TI - [Light- and electronmicroscopy studies and cultivation attempts of metallogenium]. PMID- 4145601 TI - [Metabolic switch from aerobic to anaerobic growth in Sacharomyces carlsbergensis following addition of glucose]. PMID- 4145602 TI - [The presence of oscillations in growing bacterial cultures]. PMID- 4145603 TI - [Regulation of monosaccharide and carboxylic acid metabolism in Rhodotorula gracilis]. PMID- 4145604 TI - [Substrate utilization and bacteriochlorophyll synthesis by Rhodospirillum rubrum under anaerobic conditions in the dark. I. Dependence of bacteriochlorophyl synthesis on substrate concentration and electron acceptor]. PMID- 4145605 TI - [Photophosphorylation and binding of phosphates to chromatophores in Rhodospirillum rubrum]. PMID- 4145606 TI - [Oxidation of sulfite in chromatiaceae (brief report)]. PMID- 4145607 TI - [Kinetics of Fe ++ oxidation in continuous cultures of Thiobacillus ferrooxidans (brief report)]. PMID- 4145609 TI - [Structure and function of the SV 40 DNA tumor virus (brief report)]. PMID- 4145608 TI - [Electrontransport system in Hydrogenomonas eutropha strain H16]. PMID- 4145610 TI - [Oncogenic viruses--a review]. PMID- 4145611 TI - [Structure and function relationship in reactivating cells of Nitrobacter winogradskyi Buch]. PMID- 4145612 TI - [Energy balance in anaerobic, spore-forming organisms]. PMID- 4145613 TI - The relation of the Epstein-Barr virus to Burkitt's lymphoma. PMID- 4145614 TI - [Regulation and function of NADH ferredoxin reductase in saccharolytic clostridia]. PMID- 4145615 TI - [Mechanism and regulation of NADPH ferredoxin reductase in Clostridium kluyveri]. PMID- 4145616 TI - [C 1 unit formation from CO 2 in clostridia. The reductive monocarbonic acid cycle]. PMID- 4145617 TI - [C 1 -unit formation from CO 2 in clostridia. The CO 2 reductase pathway]. PMID- 4145619 TI - [Enzyme studies on a clostridium strain (Cl. butyricum M55) with oncolytic action]. PMID- 4145618 TI - [Quantitative determination of adenine nucleotides in growing cell cultures]. PMID- 4145620 TI - [Elastase in pseudomonas and aeromonas]. PMID- 4145621 TI - [Unsaturated fatty acid metabolism in Staphylococcus aureus]. PMID- 4145622 TI - [Differentiation between anaerobic organisms using gaschromatographic metabolic analyses]. PMID- 4145623 TI - [Microbiological cleavage of racemates]. PMID- 4145624 TI - [Tryptanthrine, an antibiotic tryptophan derivative from Candida lipolytica (brief report)]. PMID- 4145625 TI - [The carotenoids of myxobacteria]. PMID- 4145626 TI - [Mechanism of mutagenesis using N-methyl-N'-nitro-N-nitroso-guanidine. Methylation of nucleic acids using N-trideuteriomethyl-N'-nitroso-guanidine]. PMID- 4145627 TI - [Demonstration of bacterial proteases using immunoelectrophoresis]. PMID- 4145628 TI - [The differentiation of membrane structures in Rhodopseudomonas capsulata (brief report)]. PMID- 4145629 TI - [Epstein-Barr virus DNA in human tumor cells]. PMID- 4145630 TI - [Escherichia coli capsular phages (brief report)]. PMID- 4145631 TI - [Structural changes in cell-wall murein in defective cell-shape mutants of Proteus mirabilis]. PMID- 4145632 TI - [Immunological and enzyme chemical studies on the cell-wall structure of Treponema pallidum]. PMID- 4145633 TI - [Relationship between the binding and effect of 14 C-polymyxin B on Salmonella typhimurium (brief report)]. PMID- 4145634 TI - [Differential liberation of enzymes from Escherichia coli B following polymycin B (brief report)]. PMID- 4145635 TI - [Penicillin sensitivity of E. Coli varies with cellular age]. PMID- 4145636 TI - [Electron microscopy and chemical analyses on the cell wall structure of Proteus mirabilis and Escherichia coli B]. PMID- 4145637 TI - [Immunity against DNA virus linked antigens in a human tumor (Burkitt's lymphoma)]. PMID- 4145638 TI - Viral etiology of leukemia and lymphomas in mice. A brief historical survey and present status. PMID- 4145639 TI - [Chicken RNA tumor viruses: a model for virus-induced carcinogenesis]. PMID- 4145640 TI - [Synthesis of structural virus proteins in SV 40 infected CV-1-cells]. PMID- 4145641 TI - [Mitoses, as a perequisite for the neoplastic cell transformation by SV 40 virus]. PMID- 4145642 TI - [Immunologic analysis of the two Herpes simplex type viruses]. PMID- 4145643 TI - [Effects of protein and DNA synthesis inhibitors on ectromelia infection]. PMID- 4145644 TI - Steady-state compositions of tissue gas pockets in rats in hyperoxic environments. PMID- 4145645 TI - [From unrecognised accident to brutality. Contribution to the diagnosis of "Silverman's syndrome"]. PMID- 4145646 TI - The immunodepressive activity of N-diazoacetylglycine derivatives in mice. PMID- 4145647 TI - [The effect of methylprylon and pyrithyldione on human chromosomes in vivo]. PMID- 4145648 TI - Repair synthesis and sedimentation analysis of DNA of human cells exposed to dimethylnitrosamine and activated dimethylnitrosamine. PMID- 4145649 TI - Mandelic acid-4-hydroxylase, a new inducible enzyme from Pseudomonas convexa. PMID- 4145650 TI - Purification and characterization of aspartic -semialdehyde dehydrogenase from yeast and purification of an isozyme of glyceraldehyde-3-phosphate dehydrogenase. PMID- 4145651 TI - Adenosine 5'-triphosphate induced cold inactivation of yeast aspartic semialdehyde dehydrogenase. PMID- 4145652 TI - Chemical reactivity at the catalytic sites of aspartic -semialdehyde dehydrogenase and glyceraldehyde-3-phosphate dehydrogenase. PMID- 4145653 TI - Some properties of hepatic reduced nicotinamide adenine dinucleotide phosphate cytochrome c reductase. PMID- 4145654 TI - Discussion on treatment failures and their management. PMID- 4145655 TI - Case-finding. PMID- 4145656 TI - Case-finding in Japan. PMID- 4145657 TI - Case-finding. PMID- 4145658 TI - Case-finding in Taiwan. PMID- 4145659 TI - Discussion on tuberculosis case-finding. PMID- 4145660 TI - B.C.G. vaccination in Japan. PMID- 4145661 TI - B.C.G. vaccination in Sabah. PMID- 4145662 TI - B.C.G. vaccination in Korea. PMID- 4145664 TI - Post-vaccination with liquid and freeze-dried B.C.G. vaccines. PMID- 4145663 TI - B.C.G. vaccination by multiple puncture method. PMID- 4145665 TI - Post vaccination keloid. PMID- 4145667 TI - The role of voluntary organisations. PMID- 4145666 TI - Discussion on B.C.G. vaccination. PMID- 4145668 TI - A study of knowledge, attitude and practice relative to tuberculosis among korean adults. PMID- 4145669 TI - Role of women's society in anti-tuberculosis activities in Japan. PMID- 4145670 TI - Assistance of the voluntary tuberculosis association in the government tuberculosis control programme with special reference to treatment supervision (Pilot projects in India). PMID- 4145671 TI - Discussion on role of voluntary organizations. PMID- 4145672 TI - Tuberculosis control and family planning programme. PMID- 4145673 TI - How regional organizations can be made more effective. PMID- 4145674 TI - How regional organisations can be made more effective (with particular reference to eastern region). PMID- 4145675 TI - Standard chemotherapy and its application in the tuberculosis programme. PMID- 4145676 TI - Chemotherapy in Japan. PMID- 4145677 TI - Chemotherapy in Taiwan. PMID- 4145678 TI - Singapore tuberculosis treatment survey. PMID- 4145679 TI - Chemotherapy in Australia. PMID- 4145680 TI - Chemotherapy in Hong Kong. PMID- 4145681 TI - Taiwan tuberculosis control programme. PMID- 4145682 TI - A follow-up study of pulmonary tuberculosis patients in Japan. PMID- 4145684 TI - The surgical treatment of pulmonary tuberculosis in Taiwan. PMID- 4145683 TI - Management of drug failure cases. PMID- 4145685 TI - Behavioral effects of drug therapy on psychogeriatric inpatients. II. Multivitamin supplement. PMID- 4145686 TI - A total hydrocarbon analyzer for use in nuclear submarines and other closed environments. PMID- 4145687 TI - Bacterial flora and infection in patients with brain injury. PMID- 4145688 TI - Increased TSH secretion in rats resulting from adiphenine administration. PMID- 4145689 TI - [Local Shwartzman reaction following infections with gram positive diplococci (pneumococci)]. PMID- 4145690 TI - [Symptoms of postvaccinal central nervous system complications and their differential diagnostic value]. PMID- 4145692 TI - Absorption, excretion and urinary metabolic pattern of 3 H-albuterol aerosol in man. PMID- 4145691 TI - [Bone marrow transplantation in radiation and chemotherapy]. PMID- 4145693 TI - Piperonyl butoxide metabolism by cytochrome P-450: factors affecting the formation and disappearance of the metabolite-cytochrome P-450 complex. PMID- 4145694 TI - Mechanism of suppressing anaphylaxis through electrolytic lesion of the tuberal region of the hypothalamus. PMID- 4145695 TI - Covalent coupling of nucleotides to agarose for affinity chromatography. PMID- 4145696 TI - Autoregulation of chronotropic response of the heart through pacemaker stretch. PMID- 4145697 TI - Relationship of thyroid and adrenal function to "fur-chewing" in the chinchilla. PMID- 4145698 TI - A method for control of water vapor pressure and its effect on metabolism and body temperature in Mus musculus. PMID- 4145699 TI - Catecholamine response of chickens to exogenous insulin and tolbutamide. PMID- 4145700 TI - Evidence of kidney chemical thermosuppression in temperature-acclimated hamsters. PMID- 4145701 TI - The effect of some nucleotides and related compounds on sodium transport and water permeability of the urinary bladder of the toad. PMID- 4145702 TI - Seasonal spontaneous torpor in the white-footed mouse, Peromyscus leucopus. PMID- 4145703 TI - Glutamate as a transmitter: comparison between the crustacean neuro-muscular junction and the chicken retina. PMID- 4145704 TI - The response of erythrocyte organic phosphate levels of active and hibernating ground squirrels (Spermophilus mexicanus) to isobaric hyperoxia. PMID- 4145705 TI - Metabolic responses to cold and catecholamines as a function of age in swine (Sus domesticus). PMID- 4145706 TI - electrophysiological studies on the olfactory sense in char (Salmo alpinus L.). PMID- 4145707 TI - The effect of temperature on ventilation in the green iguana (Iguana iguana). PMID- 4145708 TI - Hyperlipemia and atherosclerosis: a preliminary note on the mechanism of action. PMID- 4145709 TI - Osmoregulation in the euryhaline elasmobranch, Dasyatis sabina. PMID- 4145710 TI - Cholinesterase activity in ganglia of gastropoda, Lymnaea stagnalis and planorbarius corneus. I. Effect of anticholinesterase agents on giant neurone depolarization by acetylcholine and its analogues. PMID- 4145711 TI - Cholinesterase activity in ganglia of gastropoda, Lymnaea stagnalis and planorbarius corneus. II. Histochemical investigation. PMID- 4145712 TI - Metabolism, pulmocutaneous water loss and respiration of eight species of ground squirrels from different environments. PMID- 4145713 TI - Environmental influences on the testis cycles of the lizards Dipsosaurus dorsalis and Xantusia vigilis. PMID- 4145714 TI - Adenosine deaminase from Metridium senile (L.) a sea anemone. PMID- 4145715 TI - The fate of noradrenaline in the sympathetic neurone. PMID- 4145716 TI - Smallpox vaccination: complications and present role. PMID- 4145717 TI - [Use of the MMPI questionnaire in the examination of alcoholics]. PMID- 4145718 TI - [Comparison of bronchodilator effects of inhalation of aerosols of hydroxyphenylorciprenaline and other beta-adrenergic agents]. PMID- 4145719 TI - [Therapy of chronic respiratory insufficiency]. PMID- 4145720 TI - The effect of buffy coat-poor blood transfusion on subsequent hemopoietic grafts. PMID- 4145721 TI - Rescue of rhesus monkeys from acute lethal graft-versus-host disease using cyclophosphamide and frozen autologous bone marrow. PMID- 4145722 TI - Treatment of severe combined immunodeficiency by a small number of pretreated nonmatched marrow cells. PMID- 4145723 TI - Popliteal lymph node weight gain assay for graft-versus-host reactivity in mice. PMID- 4145724 TI - Participation of mesothelial cells in the graft-versus-host reaction. PMID- 4145725 TI - The male antigen in the rat. PMID- 4145726 TI - Fate of deoxyribonucleic acid-synthesizing cells and their progeny in a local graft-versus-host reaction. PMID- 4145727 TI - Time course and mechanism by which alloantiserum raised against thoracic duct lymphocytes abrogates runt disease in the rat. PMID- 4145728 TI - Tissue lactate dehydrogenase in cardiac transplantation. Toxic effect of azathioprine. PMID- 4145729 TI - Changing in vitro leucocyte migration and transformation responses in renal allograft recipients. PMID- 4145730 TI - Depletion of specific graft-versus-host reactivity following adsorption of nonsensitized lymphocytes on allogeneic fibroblasts. PMID- 4145731 TI - Effect of antigraft strain antibodies on skin allografts in immunologically tolerant mice. PMID- 4145732 TI - Influence of oxisuran, a differential inhibitor of cell-mediated hypersensitivity, on allograft survival and humoral immunity. PMID- 4145733 TI - Use of living related HL-A-nonidentical donors in renal transplantation. PMID- 4145734 TI - Prolonged survival of murine skin grafted across a weak histocompatibility barrier as a function of skin-grafting technique. PMID- 4145735 TI - [Effect of hydrocortisone on hexokinase and adenosine triphosphatase activity in rabbit brain tissue]. PMID- 4145736 TI - [Is Practolol (ICI-50172) a cardioselective beta-blockader?]. PMID- 4145737 TI - [The effects of central cholinolytics on postnystagmus and various vestibulo autonomic reactions]. PMID- 4145738 TI - Crohn's disease: a clinical study of 75 patients. PMID- 4145739 TI - The use of diaminobenzidine for spectrophotometric and acrylamide gel detection of sulfite oxidase and its applicability to hydrogen peroxide-generating enzymes. PMID- 4145740 TI - A rapid micromethod for determination of FMN and FAD in mixtures. PMID- 4145741 TI - The evidence for genetic components in the neuroses. A review. PMID- 4145742 TI - The first long-acting ("retard") thymoanaleptic or antidepressant: the time released dibenzepine with prolonged action. PMID- 4145743 TI - Hypotensive effects of the completely dereserpinised extract of Rauwolfia vomitoria. PMID- 4145744 TI - Ca 2+ -dependent allosteric regulation of nicotinamide nucleotide transhydrogenase from Pseudomonas aeruginosa. PMID- 4145745 TI - Action of chaotropic agents on drug-metabolizing enzymes in hepatic microsomes. PMID- 4145747 TI - Roles of metabolic level and temperature regulation in the adjustment of western plumed pigeons (Lophophaps ferruginea) to desert conditions. PMID- 4145746 TI - Properties of hedgehog immunoglobulin IgG2. PMID- 4145748 TI - Several blood and circulatory changes in the hibernation of the 13-lined ground squirrel, Citellus tridecemlineatus. PMID- 4145750 TI - Alteration of the blood-brain barrier system by hypothermia: critical time period vs. critical temperature. PMID- 4145749 TI - Food consumption and energy, water, and nitrogen budgets in captive great-horned owls (Bubo virginianus). PMID- 4145751 TI - The effect of taurine on the pigmentation of the bullfrog tadpole. PMID- 4145752 TI - Plasma lipid changes in genetically different types of cattle during hyperthermia. PMID- 4145753 TI - The redox state of the free nicotinamide-adenine dinucleotide couple in the cytoplasm and mitochondria of muscle tissue from Ascaris lumbricoides (Nematoda). PMID- 4145754 TI - Foetal respiration rates and the development of a stable respiratory metabolism in quail. PMID- 4145755 TI - Development of thermoregulation in painted quail, Excalfactoria chinensis. PMID- 4145756 TI - Metabolic effects of starvation in the eel, Anguilla anguilla L. PMID- 4145757 TI - Temperature regulation in free-swimming bluefin tuna. PMID- 4145759 TI - Olfactory responses to amino acids in rainbow trout, Salmo gairdneri. PMID- 4145758 TI - Amylase and other protein components of parotid saliva of the baboon, Papio anubis. PMID- 4145760 TI - Role of Na-K-ATPase in the renal reabsorption of sodium in the elasmobranch, Squalus acanthias. PMID- 4145761 TI - A moveable electrode for brain stimulation in fishes. PMID- 4145762 TI - Plasmatic and erythrocytic electrolytes in iron-deficiency anemia of pigs (Sus scrofa). PMID- 4145763 TI - Biology of Myotis thysanodes and M. lucifugus (Chiroptera: Vespertilionidae). II. Bioenergetics of pregnancy and lactation. PMID- 4145764 TI - The effect of water deprivation and hypertonic salt injection on several rodent species compared with the albino rat. PMID- 4145765 TI - Skeletal muscle function and sustained swimming speeds in the coalfish Gadus virens L. PMID- 4145766 TI - Comparative effects of continual lighting and pinealectomy on the eyes, the Harderian glands and reproduction in pigmented and albino rats. PMID- 4145767 TI - Effects of solar radiation and windchill on skin temperature of the harp seal, Pagophilus groenlandicus (Erxleben, 1777). PMID- 4145768 TI - Physiological and ecological studies on the chisel-toothed kangaroo rat, Dipodomys microps. PMID- 4145769 TI - The circannual variations in the total serum lipids and cholesterol with respect to body weight in the woodchuck (Marmota monax). PMID- 4145770 TI - Respiratory mechanics in the bird. PMID- 4145771 TI - The measurement of unidirectional sodium fluxes in the non-stressed ammocoete river lamprey, Lampetra fluviatilis L. PMID- 4145772 TI - The influence of intrahypothalamic implants of progesterone on ovarian growth and function in the ovoviviparous iguanid lizard, Sceloporus cyanogenys. PMID- 4145773 TI - Plasma progesterone in snakes. PMID- 4145774 TI - The specificity of the renin-angiotensinogen reaction through the phylogenetic scale. PMID- 4145775 TI - Factors conditioning the awakening reaction of olfactory origin in the lungfish (Protopterus annectens). PMID- 4145776 TI - The renal medulla and water economy in vesper sparrows (Pooecetes gramineus). PMID- 4145777 TI - A technique for obtaining the electrocardiogram of fish. PMID- 4145778 TI - Seasonal variation in blood viscosity of the hibernating arctic ground squirrel (Spermophilus undulatus plesius). PMID- 4145779 TI - Studies on the induction and repression of enzymes in rat liver. Characterization and metabolic regulation of multiple forms of tyrosine aminotransferase. PMID- 4145780 TI - The steric course with respect to the reduced nicotinamide-adenine dinucleotide of the reduction of 3-oxo steroids catalysed by cortisone reductase. PMID- 4145781 TI - [Extraction photometric determination of anabasine and nicotine]. PMID- 4145782 TI - Hepatomegaly: parameter of chronic experimental drug toxicity. PMID- 4145783 TI - Personality differences between one-time and recidivist unwed mothers. PMID- 4145784 TI - [EKG changes in acute pachycarpine poisoning]. PMID- 4145785 TI - [Clinical study of modirit (apropos of 30 cases)]. PMID- 4145787 TI - [Activity of liver excretory enzymes in blood serum, bile and liver tissue of patients with inserted Kehr drain, following operation because of cholelithiasis]. PMID- 4145786 TI - The -glutamyl cycle in the choroid plexus: its possible function in amino acid transport. AB - Various anatomic regions of rabbit brain have been examined for activities of the enzymes of the gamma-glutamyl cycle. While these enzyme activities were widely distributed in the brain, they are present in much higher concentrations in the choroid plexus than in other parts of the brain. The activities observed are of about the same order of magnitude as found in the kidney. These observations and other considerations suggest that the gamma-glutamyl cycle may play a significant role in the transport of amino acids between blood and cerebrospinal fluid. PMID- 4145788 TI - [The effect of dental health information and fluoride tablets on the incidence of caries in school children. I. Experimental results after a 2-year period]. PMID- 4145789 TI - The hormones of the hypothalamus. PMID- 4145790 TI - [Osteomyelitis in closed and open fractures]. PMID- 4145791 TI - [Measuring the degree of wakefulness]. PMID- 4145793 TI - [A feldsher from the Lenin river (Aleksei Stakhievich Goncharenko)]. PMID- 4145792 TI - Autonomic imbalance in asthma with special reference to beta adrenergic blockade. PMID- 4145794 TI - A clinical and spirometric trial of a new receptor stimulant drug, terbutaline, in asthmaic patients. PMID- 4145795 TI - Studies on the mechanisms of action of phenylalanine hydroxylase and its protein stimulator. I. Enzyme concentration dependence of the specific activity of phenylalanine hydroxylase due to a nonenzymatic step. PMID- 4145796 TI - Tetrahydropterin oxidation without hydroxylation catalyzed by rat liver phenylalanine hydroxylase. PMID- 4145797 TI - Regulation of fatty acid synthesis in isolated hepatocytes. Evidence for a physiological role for long chain fatty acyl coenzyme A and citrate. PMID- 4145798 TI - Glutamine synthetase and the regulation of histidase formation in Klebsiella aerogenes. PMID- 4145799 TI - The stimulation of rat liver phenylalanine hydroxylase by lysolecithin and chymotrypsin. PMID- 4145800 TI - Direct evidence for carbanions and covalent N 5 -flavin-carbanion adducts as catalytic intermediates in the oxidation of nitroethane by D-amino acid oxidase. PMID- 4145801 TI - Summary of First International Symposium on Intracranial Pressure, Hannover, Germany, July 27-29, 1972. PMID- 4145802 TI - [Studies on active principles of tar. 3. Antihistaminic and antifungal constituents in dry distillation tar of non-fat soybean]. PMID- 4145803 TI - Beta-adrenergic receptor blocking drugs. PMID- 4145804 TI - Role of the beta adrenergic receptor in the elevation of adenosine cyclic 3',5' monophosphate and induction of serotonin N-acetyltransferase in rat pineal glands. PMID- 4145805 TI - The inhibition of alcohol and aldehyde dehydrogenases by propranolol. PMID- 4145806 TI - [Experiences with mass vaccination--postvaccinal reactions and complications]. PMID- 4145807 TI - [Professional section of the Trade Union of Health Service Employees]. PMID- 4145808 TI - [Our young people]. PMID- 4145809 TI - [Responses of pneumococcal and staphylococcal polysaccharides to rheumatoid sera]. PMID- 4145810 TI - [Microplasma welding in dentistry (experimental study)]. PMID- 4145811 TI - [Accumulation of glycogen in the neutrophilic granulocytes in experimental inflammatory reaction of the cornea]. PMID- 4145812 TI - Adverse reactions to duck embryo rabies vaccine. Range and incidence. PMID- 4145813 TI - Hypertension 1973: treatment--why and how. PMID- 4145814 TI - Function and regulation of NADP-specific malate dehydrogenase in Euglena gracilis Z. PMID- 4145815 TI - The involvement of semidehydroascorbate reductase in the oxidation of NADH by lipid peroxide in mitochondria and microsomes. PMID- 4145816 TI - Studies on human polymorphonuclear leukocyte enzymes. I. Assay of acid hydrolases and other enzymes. PMID- 4145817 TI - Studies on human polymorphonuclear leukocyte enzymes. II. Comparative study of the physical properties of primary and specific granules. PMID- 4145818 TI - Inhibition of urocanase by cupric ion. PMID- 4145819 TI - Treatment of acute arrhythmias with orally administered tolamolol. PMID- 4145821 TI - [Electrogastro-enterographic approach to digestive adrenergic receptors in awake man]. PMID- 4145820 TI - [Central mechanism in the rabbit contributing to hyperglycemia induced by ethyl carbamate]. PMID- 4145822 TI - [Relationship between increased oxygen consumption of a muscular area by catecholamines and their vasomotor effects]. PMID- 4145823 TI - [Possibilities of determining female mosquitoes by microscopic preparations of the head. I. Systematic signs and characteristics of the genus]. PMID- 4145824 TI - [Importance of renal angiography in the diagnosis of periarteritis nodosa]. PMID- 4145825 TI - Neurophysiologic effects of general anesthetics. I. The electroencephalogram and sensory evoked responses in man. PMID- 4145826 TI - [Gilles de la Tourette's disease based on five own observations]. PMID- 4145827 TI - Coenzyme dissociation, a possible determinant of short half-life of inducible enzymes in mammalian liver. PMID- 4145828 TI - Regulation of glucose-6-phosphate dehydrogenase activity in red blood cells from hemolytic and nonhemolytic variant subjects. PMID- 4145829 TI - Formation of C 21 -17-hydroxysteroids and C 19 -steroids from 3 -hydroxypregn-5 en-20-one and progesterone in vitro by germ cells from immature rat testes. PMID- 4145830 TI - [Effect of the characteristics of the work of electronic computer keyboard operators on certain physiological changes]. PMID- 4145831 TI - Pharmacology and acute toxicity of essential oil extracted from Zanthoxylum budrunga. PMID- 4145832 TI - Comparison of techniques for taking liver and lung samples from small rodents for bacteriological culture. PMID- 4145833 TI - [Polyarteritis nodosa: anatomo-clinical correlation of 3 cases]. PMID- 4145834 TI - [Micro-crossover electrophoresis for the detection of Au-SH-antigen]. PMID- 4145835 TI - [Species of the genus bifdobacterium found in human vagina]. PMID- 4145836 TI - [R-factor transmission in E. coli: a function of the growth phase of donor cells]. PMID- 4145837 TI - [Studies on oxytetracycline binding of salmonella R mutants]. PMID- 4145838 TI - [Neuraminidase activity, hemolysin, permeability factor and lethal toxin in filtrates of halophilic sea vibrios]. PMID- 4145839 TI - [The effect of ampicillin and pivampicillin on the intestinal flora of man]. PMID- 4145840 TI - [The fecal flora in man. I. Composition of the fecal flora of various age groups]. PMID- 4145841 TI - [Megasphaera elsdenii--a normal inhabitant of human large intestine]. PMID- 4145842 TI - Influence of nutritional doses of virginiamycin and spiramycin on the quantitative and topographical composition of the gastro-intestinal flora of artificially reared piglets. PMID- 4145843 TI - [Differentiation between the genera bacteroides and sphaerophorus based on the structure of their complex lipids]. PMID- 4145844 TI - A plea against sex conversion in nomenclature. PMID- 4145845 TI - [Vancomycin-resistance of leptospirae]. PMID- 4145846 TI - [Technic of disc-electrophoresis for the differentiation of avian mycoplasma]. PMID- 4145847 TI - [Serological and seroepidemiological studies on complement-binding chlamydia antibodies--a contribution on the understanding of ornithosis]. PMID- 4145848 TI - [Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse]. PMID- 4145849 TI - [Tetrachlorvinphos--an effective insecticide against ticks]. PMID- 4145850 TI - [Intraperitoneal infection of mice with Ecchinococcus multilocularis in relation to the age of the infectious material used]. PMID- 4145851 TI - [The O-diphenoloxidase reaction with pyrocatechol for the differentiation of Cryptococcus neoformans]. PMID- 4145852 TI - Ventricular fibrillation in the course of Prinzmetal's angina pectoris. Report of two cases. PMID- 4145853 TI - Systemic lupus erythematosus syndrome induced by practolol. AB - Three patients with angina pectoris treated with practolol in varying doses developed a syndrome of arthralgia, particularly of the small joints of the hands, rash, fever, a raised E.S.R., and positive tests for lupus erythematosus (L.E.) cells and antinuclear antibody. The syndrome responded partly to withdrawal of the drug, but steroids were required to produce adequate symptomatic improvement. These disease features suggest that this is an example of drug-induced systemic lupus erythematosus (S.L.E.). The impaired ability of lymphocytes from these patients to transform in vitro indicates a testable hypothesis for the pathogenesis of the syndrome. PMID- 4145854 TI - [Current vaccination problems]. PMID- 4145855 TI - Adrenergic receptors. PMID- 4145856 TI - Nonutility of measurement of serum gamma-glutamyl transpeptidase activities in diagnosis of myocardial disease. PMID- 4145857 TI - UV spectrophotometry in medium-band instruments. PMID- 4145858 TI - A dose-response study of propranolol in chronic schizophrenics. PMID- 4145859 TI - Histochemical studies of the mucosa of the small intestine in impaired absorption syndromes in children. PMID- 4145860 TI - Enzymatic studies of the dental pulp in dogs. II. Succinate dehydrogenase, 6 phosphogluconate dehydrogenase, NADH 2 tetrazolium reductase, glucose-6 phosphatase and phosphorylases. PMID- 4145861 TI - Changes in isozyme patterns between monokaryons and dikaryons of a bipolar Coprinus. AB - Proteins and isozymes of several different classes of enzymes in partially purified protein extracts of monokaryons, dikaryons, and monokaryon mixtures of a bipolar Coprinus sp. were separated on polyacrylamide gels by slab electrophoresis. Differences in protein and isozyme spectra were correlated with the operation of the incompatibility factors and with the results of Wang and Raper on Schizophyllum. It was concluded that the shift from monokaryon to dikaryon mediated a major change in the nature, quantity, or distribution of the proteins of this Coprinus sp. PMID- 4145863 TI - Nitrate reduction and the growth of Veillonella alcalescens. AB - Veillonella alcalescens, a strict anaerobe, was found to possess a nitrate reductase system which has characteristics of both assimilatory and respiratory nitrate reduction. The nitrate reductase has been identified tentatively as a particulate enzyme which utilizes a variety of electron donors for the reduction of nitrate. By use of (15)N-labeled nitrate, it was shown that under appropriate conditions nitrate nitrogen is incorporated into cell material. V. alcalescens grown on pyruvate and nitrate has a greater growth rate than cells grown on pyruvate alone. Growth can occur in a medium with hydrogen and nitrate as the sole energy source. Ammonium chloride decreases the rate of nitrate reduction but does not completely inhibit reduction or incorporation. The results suggest that nitrate assimilation and respiration are not as distinct as in some other organisms. PMID- 4145862 TI - Restriction and modification of bacteriophage S2 in Haemophilus influenzae. AB - The major conclusion from these studies is that variants of Haemophilus influenzae Rd which restrict and modify phage S2 are metastable and capable of giving rise to one another with high frequency. Nonrestrictive RdS cells segregate spontaneously to the restricting, modifying phenotype in about 5% of the progeny of a single clone. The restrictive cells derived from RdS revert to the nonrestrictive phenotype in 15 to 25% of the progeny of a single clone. These frequencies are not appreciably affected by treatment with acriflavine or ethidium bromide, compounds which affect plasmid stability, or by nitrosoguanidine, a powerful mutagen. The genetic locus for restriction and modification of bacteriophage S2 is found to have a chromosomal position between the biotin and proline loci. Restriction-modification of phage S2 has been shown to be a function of its deoxyribonucleic acid (DNA) in that transfection with S2 phage DNA or prophage DNA is subject to host restriction and modification. An enzyme preparation, which contains endodeoxyribonuclease but no appreciable exonuclease activity, from mutant H. influenzae com(-10) did not restrict phage S2.RdS DNA or prophage DNA transfecting activity, indicating that this endodeoxyribonuclease is not responsible for phage restriction. A new restriction enzyme isolated from H. influenzae Rd was found to be the major enzyme involved in the restriction of bacteriophage S2. The enzyme inactivated the transfecting activity of unmodified phage DNA but did not attack modified phage DNA. Unlike endodeoxyribonuclease R, this enzyme requires adenosine triphosphate and S adenosylmethionine. PMID- 4145865 TI - Ammonium regulation in Aspergillus nidulans. AB - l-Glutamate uptake, thiourea uptake, and methylammonium uptake and the intracellular ammonium concentration were measured in wild-type and mutant cells of Aspergillus nidulans held in various concentrations of ammonium and urea. The levels of l-glutamate uptake, thiourea uptake, nitrate reductase, and hypoxanthine dehydrogenase activity are determined by the extracellular ammonium concentration. The level of methylammonium uptake is determined by the intracellular ammonium concentration. The uptake and enzyme characteristics of the ammonium-derepressed mutants, meaA8, meaB6, DER3, amrA1, xprD1, and gdhA1, are described. The gdhA mutants lack normal nicotinamide adenine dinucleotide phosphate-glutamate dehydrogenase (NADP-GDH) activity and are derepressed with respect to both external and internal ammonium. The other mutant classes are derepressed only with respect to external ammonium. The mutants meaA8, DER3, amrA1, and xprD1 have low levels of one or more of the l-glutamate, thiourea, and methylammonium uptake systems. A model for ammonium regulation in A. nidulans is put forward which suggests: (i) NADP-GDH located in the cell membrane complexes with extracellular ammonium. This first regulatory complex determines the level of l-glutamate uptake, thiourea uptake, nitrate reductase, and xanthine dehydrogenase by repression or inhibition, or both. (ii) NADP-GDH also complexes with intracellular ammonium. This second and different form of regulatory complex determines the level of methylammonium uptake by repression or inhibition, or both. PMID- 4145866 TI - The relationship between blood levels of different forms of butaperazine and clinical response. PMID- 4145864 TI - Membranes of Bacillus stearothermophilus: factors affecting protoplast stability and thermostability of alkaline phosphatase and reduced nicotinamide adenine dinucleotide oxidase. AB - Protoplasts of Bacillus stearothermophilus NCA 1503-4R are resistant to osmotic rupture and are not sensitive to mechanical manipulation. Protoplast stability is maintained by divalent cations. The thermostability of protoplasts is enhanced when the cells are grown at elevated temperatures. The membrane content of the cell and the protein-to-lipid ratio of the membrane increases as the growth temperature is increased. The membrane-bound nicotinamide adenine dinucleotide (reduced form) oxidase system from cultures grown at 70 C was more thermostable than the same enzyme system from cultures grown at 55 C. Alkaline phosphatase was resistant to thermal inactivation in the intact protoplast. The extent of this protection is dependent on protoplast stability. PMID- 4145867 TI - A study of filariasis in an aggregated community of Banaras Hindu University township. PMID- 4145868 TI - Immune status of SJL-J mice in relation to age and spontaneous tumor development. PMID- 4145869 TI - Control of -aminolevulinic acid synthetase and tyrosine aminotransferase in tumors and livers of tumor-bearing rats. PMID- 4145870 TI - Growth and behavioral changes in developing rats treated intracisternally with 6 hydroxydopamine: evidence for involvement of brain dopamine. PMID- 4145871 TI - [Nonspecific host defence of neurotropic arbovirus infections]. PMID- 4145872 TI - [Standardization of the hemagglutination-inhibition test for two equine influenza viruses]. PMID- 4145873 TI - [Further studies on influenza-immunity by means of a mouse-lethal influenza virus strain A-Hong Kong. 3]. PMID- 4145874 TI - [Fecal carrier rate and enterotoxigenicity of staphylococcus aureus in man]. PMID- 4145875 TI - Influence of staphylococci and Pseudomonas aeruginosa on the growth of Acholeplasmataceae and Mycoplasmataceae. PMID- 4145876 TI - Studies on the dynamics of multiplication and virulence of salmonella typhi murium cultured in the presence of sideramine. PMID- 4145877 TI - [Occurrence of Bacteroides thetaiotaomicron in animals]. PMID- 4145878 TI - [In vitro studies of the erysipelothrix insidiosa neuraminidase]. PMID- 4145879 TI - Typing of leptospira strains of the hebdomadis serogropuy with absorbed sera. PMID- 4145880 TI - [Occurrence of serological types of the serological group australis of leptospirae in Bulgaria]. PMID- 4145881 TI - [Quantitative and qualitative study of yeast-like fungi of men]. PMID- 4145882 TI - [Development of protoscolices of echinococcus multilocularis in experimentally infected mice in dependence on age and sex of the experimental animals and on infection --prerequisites for the development of a test model]. PMID- 4145883 TI - [Formation of calcareous corpuscles due to echinococcus multilocularis in experimentally infected mice in dependence of age and sex of the animal and of infection dose--prerequisites for the development of a test model]. PMID- 4145884 TI - Methicillin-resistant staphylococcus aureus strains. PMID- 4145885 TI - [Various circulatory effects of m-oxyphenyl ethanol ethylamine and its modifications by alpha and beta adrenergic block]. PMID- 4145886 TI - Effects of antilymphocyte serum: evidence of the maturation process of lymphoid and haemopoietic cells under in vitro cultivation. PMID- 4145887 TI - Cutaneous reactions to cardiovascular drugs. PMID- 4145888 TI - Biochemical changes in the platelet energy transferring system during concomitant action of cephalin and serotonin. PMID- 4145889 TI - Effect of fructose and glyceraldehyde on ethanol metabolism in human liver and in rat liver. PMID- 4145890 TI - The purification and properties of an NADPH-linked aldehyde reductase from pig brain. PMID- 4145891 TI - Responses of sympathetic chain-ganglia isolated in organo-typic culture to agents affecting adrenergic neurons: fluorescence histochemistry. PMID- 4145892 TI - Physical properties of mouse spleen cells involved in the mixed leukocyte reaction and graft-vs-host disease. PMID- 4145893 TI - Central core disease. A study of clinically unaffected muscle. PMID- 4145894 TI - Function of T4D structural dihydrofolate reductase in bacteriophage infection. AB - Various properties of the bacteriophage structural dihydrofolate reductase (DFR) have been examined to determine its function during phage infection. It has been found that a binding site for reduced nicotinamide adenine dinucleotide phosphate (NADPH), most likely on the DFR present in the phage tail plate, is required for phage viability. Attachment of adenosine diphosphoribose, an analogue of NADPH, to this site prevents phage adsorption and injection. This adenosine diphosphoribose inhibition can be competitively reversed by the addition of NADPH or oxidized nicotinamide adenine dinucleotide phosphate. It is suggested that, during phage infection, the host bacterial cell might leak compounds functionally similar to the pyridine nucleotides. These compounds have been shown to nonenzymatically change the conformation of the phage tail plate DFR which is apparently necessary for successful injection. PMID- 4145895 TI - This is the AMA. PMID- 4145896 TI - [Osteochondrosis dissecans]. PMID- 4145897 TI - [Trigger finger]. PMID- 4145898 TI - [Analysis of traumatic deaths]. PMID- 4145899 TI - [Therapeutic problems in diaphyseal fractures in patients with combined nailed osteosynthesis for previous femoral neck fracture]. PMID- 4145900 TI - [Dysplasia epiphysealis hemimelica]. PMID- 4145901 TI - [Benign tumors of the soft tissues invading the bone]. PMID- 4145902 TI - [Rotation osteotomy on the tibia]. PMID- 4145903 TI - [Nailing of the femoral neck with a faulty technic]. PMID- 4145904 TI - [Prof. Lorenz Bohler]. PMID- 4145905 TI - [The importance of the intra-articular pressure increase and laceration of the joint capsule occurring in femoral neck fractures]. PMID- 4145906 TI - [Simultaneous occurrence of fractures of the femoral neck and diaphysis in the same extremity]. PMID- 4145907 TI - [Artificial feeding of patients with severe craniocerebral injuries]. PMID- 4145909 TI - Studies with synthetic LH-releasing hormone in the human. II. Evaluation of anterior pituitary gonadotropic function in various endocrine states. PMID- 4145908 TI - Neurotransmitter regulation of ACTH release. PMID- 4145910 TI - Nervous control of growth hormone secretion. PMID- 4145911 TI - Histochemical studies on phosphorylase activity in the tissues of the albino rat under normal and experimental conditions. V. Effects of experimental cryptorchism on testis phosphorylase. PMID- 4145912 TI - Efficacy of clindamycin therapy for otitis media. PMID- 4145913 TI - Feeding and drinking deficits after 6-hydroxydopamine administration in the rat: similarities to the lateral hypothalamic syndrome. PMID- 4145914 TI - Voltammetry in brain tissue--a new neurophysiological measurement. PMID- 4145915 TI - [Increased incidence of dental caries with progressing age in school children in Szczecin]. PMID- 4145916 TI - [Oral hygiene, periodontal diseases and dental caries]. PMID- 4145917 TI - [Occurrence of dental caries in dystrophic and mixed forms of parodontopathy]. PMID- 4145918 TI - [Carbromal poisoning]. PMID- 4145919 TI - [Development of a toothbrush for children based on clinical experimental longitudinal studies]. PMID- 4145920 TI - Sex dependency of steroid retention in rat-liver slices incubated with testosterone. PMID- 4145921 TI - Properties of purified malic enzyme in relation to crassulacean acid metabolism. PMID- 4145922 TI - Molecular restriction of anti-DNP antibodies induced by dinitrophenylated type 3 pneumococcus. PMID- 4145923 TI - Alternative potentiating and inhibitory effects of GVH reaction on formation of antibodies against a thymus-independent polysaccharide (S3). PMID- 4145924 TI - Glycogen and related enzymes in normal and cryptorchid human testes: a cytochemical study. PMID- 4145925 TI - The effects of artificial cryptorchidism in the rabbit on the transport and survival of spermatozoa in the female reproductive tract. PMID- 4145926 TI - Reserpine, adrenalectomy and the reversal of the early action of cadmium on scrotal and cryptorchid testes in the rat. PMID- 4145927 TI - Industrial injuries. PMID- 4145928 TI - [Attempt at classification of psychotropic drugs]. PMID- 4145929 TI - [In vitro effect of natural antiallergic substances]. PMID- 4145930 TI - [Influence of the degree of decalcification of allogenic bone implants in experimental osteogenesis]. PMID- 4145931 TI - Experience with automation as an aid in the management of diabetes. PMID- 4145932 TI - Locus of control among schizophrenics and other hospitalized psychiatric patients. PMID- 4145933 TI - Effect of pneumococcal neuraminidase on canine cerebral cortex in experimental meningitis. AB - We examined the effect of experimental meningeal infection with a neuraminidase producing strain of Diplococcus pneumoniae on the N-acetylneuraminic acid (NANA) content of canine cerebral cortical gray matter. The Warren thiobarbituric acid assay for NANA was used. There was no significant difference between the free and bound NANA levels of the tissue from control animals and from those with meningitis. This finding suggests that the neurological impairment so frequent in clinical pneumococcal meningitis is not a result of the activity of this bacterial enzyme upon cortical glycolipids. PMID- 4145934 TI - The significance of statistics. PMID- 4145935 TI - [Research into soldering with silver alloy]. PMID- 4145936 TI - [Use of Begg technique in the treatment of mutilation cases]. PMID- 4145937 TI - [Computer analysis of the ECG]. PMID- 4145938 TI - [Modern rehabilitation measures in orthyopedics and traumatology]. PMID- 4145939 TI - [Early diagnosis and its significance for the prevention of rheumatic joint diseases]. PMID- 4145940 TI - [Late result of multicentric follow-up studies on myocardial infarct]. PMID- 4145941 TI - [Expert opinion and jurisdiction in polyragmasy]. PMID- 4145942 TI - [Prognosis of heart insufficiency]. PMID- 4145943 TI - [Current problems in therapy with antibiotics]. PMID- 4145944 TI - Personality characteristics of alcoholics as college freshman and at time of treatment. PMID- 4145945 TI - The methods and results of caries prevention with fluorides in Hungary and in Eastern European countries. PMID- 4145946 TI - [Pyrocatecholamines and myocardial function]. PMID- 4145947 TI - [Histochemical studies in malpositions of the testis following treatment with human chorionic gonadotropin (HCG) in animal experiment and clinical patient material]. PMID- 4145948 TI - Caries progression and activity in approximal tooth surfaces. A longitudinal study. PMID- 4145949 TI - Acute abdomen in rheumatoid arthritis due to necrotizing arteritis. PMID- 4145951 TI - Testicular tumours associated with undescended testes. A retrospective study of 45 cases. PMID- 4145950 TI - Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine. PMID- 4145952 TI - The Peyer's patches as thymus-independent lymphoid tissue. PMID- 4145953 TI - Effect of bile salts on partitioning behavior and GI absorption of a quaternary ammonium compound, isopropamide iodide. PMID- 4145954 TI - Steric aspects of adrenergic drugs. XXII. Retention of (+)- and (-)- 14 C norepinephrine by mouse heart. PMID- 4145955 TI - A physician-associate program at a municipal hospital. PMID- 4145956 TI - [Effect of selective deep hypothermia, isolated or associated with alpha adrenergic receptor block, on ischemic renal transplants]. PMID- 4145958 TI - [Performance of normally intelligent children with organically reduced cerebral capacity under the effect of cerutil in a task performing experiment]. PMID- 4145957 TI - The use of modified cellulose papers in routine toxicological analysis. 2. Antidepressives and antihistaminics. PMID- 4145959 TI - Crystallization of NADP-specific isocitrate dehydrogenase. AB - The first crystalline preparation of isocitrate dehydrogenase specific for nicotinamide adenine dinucleotide phosphate has been obtained with enzyme isolated from Escherichia coli. Scanning electron microscopy was employed to elucidate the structure of the crystals, which were found to exist as regular octahedrons ranging in size from 5 to 90 micrometers. PMID- 4145960 TI - Ortho-chlorobenzylmalononitrile: a metabolite formed from ortho chlorobenzylidenemalononitrile (CS). PMID- 4145961 TI - Detection of a graft-versus-host reaction between mice compatible at the H-2 locus. PMID- 4145962 TI - Failure of hybrid resistance on macrophage layer formed in peritoneal cavity of F 1 mice. PMID- 4145963 TI - [Role of mosquitoes in the transmission of the causative agent of anaplasmosis]. PMID- 4145964 TI - [Histochemical properties of "C" cells and solid thyroid cancers with stromal amyloidosis]. PMID- 4145965 TI - Myocardial and skeletal muscle responses to hemorrhage and shock during adrenergic blockade. PMID- 4145966 TI - Effects of catecholamines on the smooth muscle of the female reproductive tract. PMID- 4145967 TI - The effect of fluoride in drinking water on the number of cavities in teeth of 15 year-old children. PMID- 4145968 TI - Reduction of glyoxylate by human serum. PMID- 4145969 TI - The role played by adrenal hormones in the increase of liver tyrosine aminotransferase activity of rats subjected to trauma. PMID- 4145970 TI - Dental caries experience and periodontal disease among black populations in Louisiana. PMID- 4145971 TI - Experimental modulation of hypothalamic content of the gonadotropic releasing factors by pineal factors in the rat. PMID- 4145972 TI - Peripheral neuropathies in diseases of internal organs. II. A survey. PMID- 4145973 TI - Cancer--the elusive enemy. PMID- 4145974 TI - Practolol-induced drug eruption. PMID- 4145975 TI - [Enzymatic diagnosis of the fetal granulomatous disease]. PMID- 4145976 TI - [Value of the determination of -glutamyl-transpeptidase ( -GT) as a screen test for liver neoplasms]. PMID- 4145977 TI - [Electrophoretic and enzymologic aspects of chronic hepatitis]. PMID- 4145978 TI - [Critical evaluation of some morphological serum enzymatic relationship and plasma protein fractions in liver diseases]. PMID- 4145979 TI - [Correlation between serum enzyme tests and histological findings in chronic hepatitis]. PMID- 4145980 TI - [Behavior of isoarylesterases in liver pathology]. PMID- 4145981 TI - [Practical significance of the serum levels of -glutamyl transpeptidase in various liver diseases]. PMID- 4145982 TI - [Evaluation of determination of -glutamyl transpeptidase ( -GT) in hepatobiliary diseases]. PMID- 4145983 TI - [The treatment of cardiac arrhythmias: complexity and schematization]. PMID- 4145984 TI - [Symposium on cattle dictyocauliasis. Recapitulation]. PMID- 4145985 TI - ICN 15th Quadrennial Congress; May 13-18, 1973, Mexico City. PMID- 4145987 TI - MMPI performance in chronic medical illness: the use of computer-derived interpretations. PMID- 4145988 TI - ICN 1973. 15th Quadrennial Congress of the International Council of Nurses. PMID- 4145986 TI - Fatty acid activation and acyl transfer in rat liver during clofibrate feeding. PMID- 4145989 TI - A rapid microtest for the detection of acetoin. PMID- 4145990 TI - [Etiology of actinomycosis of the mammary gland of the pig]. PMID- 4145991 TI - Immunoglobulins and complement in Chagas' disease. PMID- 4145992 TI - [Worm load in secondary echinococcosis of mice in dependence on age and sex of the experimental animals and on infection dose--assumptions for construction of a model test]. PMID- 4145994 TI - [Species of cryptococcus on seeds]. PMID- 4145993 TI - [Trimethoprim-sulphamethoxazole (septrin) for therapy of long-term carriers of typhoid bacteria. Preliminary report]. PMID- 4145995 TI - [Theory of the quantitative haemadsorption test]. PMID- 4145996 TI - [Biological activity of mercaptoethanol-treated and substituted influenza virus particles]. PMID- 4145997 TI - The occurrence of enterotoxigenic staphylococcus aureus strains in hosts of different animal species. PMID- 4145998 TI - [Turbidimetric determination of the phage sensitivity of staphylococcal strains (preliminary communication)]. PMID- 4145999 TI - Experimental studies on the epidemiological importance of the cockroach, Blattella germanica (L.), in streptococcal infections on ships. PMID- 4146000 TI - Combined effect of the pH of the growth medium and the incubation temperature on the morphology of bacterium anitratum. PMID- 4146001 TI - [A simplified antigenic scheme for Yersinia enterocolitica (syn. "Pasteurella X") based on biochemical characteristics]. PMID- 4146002 TI - A treatment need survey of a 15-year-old population. PMID- 4146003 TI - Measuring restorative dental care in communities. PMID- 4146004 TI - Effect of alpha- and beta-blocking drugs on the clotting and fibrinolytic response to venous status in man. PMID- 4146005 TI - An apparent epidemic: methadone poisoning in children. PMID- 4146006 TI - Evaluation of screendex--a multireagent system for detection of drug abuse and drug overdose. PMID- 4146007 TI - Sympathetic nerve cultures as a tool for the pharmacological study of sympathetic terminals. PMID- 4146008 TI - Effects of some psychotropic drugs on tyrosine hydroxylase activity in different structures of the rat brain. PMID- 4146009 TI - Further studies on the -adrenoceptor blocking action of -adrenoceptor blocking agents. PMID- 4146011 TI - Dislocation of the cuboid. PMID- 4146010 TI - Effects of pharmacological agents on the in vivo release of melanophore stimulating hormone in the dogfish, Scyliorhinus canicula. PMID- 4146013 TI - Acquisition of verbal concepts as a function of explicit and implicit experimental demands and repression-sensitization. PMID- 4146012 TI - FSH. I. Evidence for its mediating role on testosterone secretion in cryptorchidism. PMID- 4146014 TI - Cardiac glycosides (heart poisons) in the polka-dot moth Syntomeida epilais Walk. (Ctenuchidae: Lep.) with some observations on the toxic qualities of Amata (=Syntomis) phegea (L.). PMID- 4146015 TI - [Use of the MMPI for the study of the progress of clinical group psychotherapy]. PMID- 4146016 TI - Clinical trials of a new antihistaminic HS 592. PMID- 4146017 TI - [Fibrinogen-fibrin degradation products in the urine. Measurement and characterization by means of electroimmunodiffusion (rapid method)]. PMID- 4146018 TI - Pharmacological studies of snake (Dendroaspis angusticeps) venom. PMID- 4146019 TI - Is transplantation tolerance in the rat serum-mediated? PMID- 4146020 TI - Modification of severe graft-versus-host disease with antisera to the (theta) antigen or to whole serum. PMID- 4146021 TI - Role of the hemoporetic inductive microenvironments (HIM) in xenogeneic bone marrow transplantation. PMID- 4146023 TI - International relations, personal conduct, and the London Congress. PMID- 4146022 TI - Peak-potentialities of inspiratory musculature as disclosed by tracheal occlusion. PMID- 4146024 TI - Immune complex disease. PMID- 4146025 TI - Oxidation and reduction of D-xylose by cell-free extract of Pichia quercuum. AB - The fermentation mechanism of the simultaneous production of D-xylonic acid and xylitol from D-xylose by Pichia quercuum was studied by using a cell-free enzyme preparation. Nicotinamide adenine dinucleotide phosphate (NADP)-dependent D xylose dehydrogenase activity and NADP-dependent D-xylose reductase activity were detected, and the oxido-reduction reaction of D-xylose was able to couple through regeneration of NADP and NADPH to produce D-xylonic acid and xylitol. PMID- 4146026 TI - Computers in behavioral science. A comprehensive automated psychological examination and report (CAPER). PMID- 4146027 TI - The haemodynamic effects of halothane in dogs. PMID- 4146028 TI - Trans-synaptic regulation of tyrosine hydroxylase activity in a developing mouse sympathetic ganglion: effects of nerve growth factor (NGF), NGF-antiserum and pempidine. PMID- 4146029 TI - [Liberation of TSH by the anterior pituitary gland of the rat under the influence of diethylamino-2-ethyl diphenylacetate]. PMID- 4146030 TI - [Lymphoblastic transformation of a fraction rich in lymphocytes isolated from human bone marrow samples and cultivated in vitro in the presence of phytochemagglutinin]. PMID- 4146031 TI - Drug induced dystonia tarda: treatment with L-dopa. PMID- 4146032 TI - Interhemispheric relationships with somatic therapy. PMID- 4146033 TI - Internal pH, pH, and the kinetics of electron transport in chloroplasts. PMID- 4146034 TI - Comparison between the affinities for reversible cholinergic ligands of a purified and membrane bound state of the acetylcholine-receptor protein from Electrophorus electricus. PMID- 4146035 TI - Anion transport in beef adrenal cortex mitochondria. PMID- 4146036 TI - Method for the isolation of iron-loaded lysosomes from rat liver. PMID- 4146037 TI - Levels of acetyl coenzyme A carboxylase and its effectors in rat liver after short-term fat-free refeeding. PMID- 4146038 TI - Activity of the hexose monophosphate shunt in a mutant of Saccharomyces carlsbergensis lacking NADP dependent glutamate dehydrogenase activity. PMID- 4146039 TI - Lymphoid cell functions in mice treated with L-asparaginase. PMID- 4146040 TI - [Impressions of the 46th Congress of the Japan Industrial Hygiene Society, the 14th Industrial Health Committee]. PMID- 4146041 TI - [A case from insurance medical practice. Payment liability of accident insurance following fatal fall down the staircase]. PMID- 4146042 TI - Radiographic detection of defects in soldered joints of dental gold alloys. PMID- 4146043 TI - [Treatment of schizophrenia with imiclopazine, pimozide, imagotan and trifluorperidol. Comparative study]. PMID- 4146044 TI - Neurohumoral control of bile secretion in the cholecystectomized, conscious dog. PMID- 4146045 TI - The antigenic stimulus in human transplantation. PMID- 4146046 TI - Physiological and immunological consequences of transplanting isolated pancreatic islets. PMID- 4146047 TI - The annual meeting--getting it all together or what to do until the psychiatrist arrives. PMID- 4146048 TI - An exhibitor looks at constituent society annual sessions. PMID- 4146049 TI - An association executive looks at the exhibitor. PMID- 4146050 TI - Effects of caloric restriction and fenfluramine on weight loss and personality profiles of patients with long standing obesity. PMID- 4146051 TI - Growth hormone modulation of liver drug metabolic enzyme activity in the rat. I. Effect of the hormone on the content and rate of reduction of microsomal cytochrome P-450. PMID- 4146052 TI - Protection by diethyldithiocarbamate against carbon tetrachloride lethality in rats and against carbon tetrachloride-induced lipid peroxidation in vitro. PMID- 4146053 TI - Evaluation of practolol in hypertension. Effects on sympathetic nervous system and renin responsiveness. PMID- 4146054 TI - Assessment of relative actions of beta-adrenergic blocking drugs on heart rate and left ventricular ejection using a non-invasive method in patients with aortic Starr-Edwards prostheses. PMID- 4146056 TI - Familial incidence of Gilles de la Tourette's disease, with observations on aetiology and treatment. PMID- 4146055 TI - Paroxysmal nocturnal haemoglobinuria and refractory marrow failure treated by marrow transplantation. PMID- 4146057 TI - Treatment of traumatically injured teeth. PMID- 4146058 TI - [Poisoning by "duck's beak" fish (belonging to the Lethrinides family)]. PMID- 4146059 TI - [Use of silica gel thin-layer chromatography for determining the identity of the preparation, "Analeptic mixture for injections"]. PMID- 4146060 TI - [Use of gel chromatography to study sphaerophysine in toxicological analysis]. PMID- 4146061 TI - [Extraction of spasmolytin from aqueous solutions with organic solvents depending on the pH of the medium]. PMID- 4146062 TI - [Psychotropic action of some aromatic substances used in food]. PMID- 4146063 TI - Oxidation of 21-dehydrocorticosteroids to steroidal 20-oxo-21-oic acids by ketoaldehyde dehydrogenase of sheep liver. PMID- 4146064 TI - Studies on 17 -hydroxysteroid dehydrogenase in immature mouse ovarian tissue. PMID- 4146065 TI - How to do it--organize your own regional journalism conference. PMID- 4146066 TI - The mechanism of some sympathomimetic amines. PMID- 4146067 TI - Case for diagnosis: leukocytoclastic vasculitis. PMID- 4146068 TI - Multiple endocrine adenomatosis and peptic ulcer. PMID- 4146069 TI - Various new clinical chemical data in the blood of normal ponies and ponies affected with hyperlipaemia (hyperlipoproteinaemia). PMID- 4146070 TI - [Histamine concentration in surgical patients]. PMID- 4146071 TI - Analeptic medication in domestic animals: species differences observed with doxapram and combinations of it with other stimulants. PMID- 4146072 TI - Influence of antihistamine drugs and beta-adrenoreceptor blockade on the vasoconstrictor effects of noradrenaline in the vascular bed of working muscles. PMID- 4146073 TI - Neural modeling. PMID- 4146074 TI - A modified method for the assay of benzo(a)pyrene hydroxylase. PMID- 4146075 TI - Pharmacological analysis of the adrenergic receptor for lipopolysaccharide-I of Shigella sonnei. PMID- 4146076 TI - Dental caries in children in the city of Wroclaw before the introduction of fluoridation of water supply in 1967. I. Material, methods of stomatological examination, statistical analysis and terminology. PMID- 4146077 TI - Dental caries in children in the city of Wroclaw before the introduction of fluoridation of water supply in the year 1967. II. Deciduous dentition. PMID- 4146078 TI - Dental caries in children in the city of Wroclaw before the introduction of fluoridation of water supply in 1967. 3. Permanent dentition. PMID- 4146079 TI - [Light and electron microscopy study of a transparent lamellar graft (Relationship with host tissue)]. PMID- 4146080 TI - [The motility-inhibiting effect of adrenergic beta receptor stimulating agents in dependence on the duration of pregnancy]. PMID- 4146081 TI - [Alkylans-alkylandum reactions. 9. Serotonin and serotonin-antagonists, histamine and antihistaminics as antialykylants]. PMID- 4146082 TI - Pediatric emergency medical care. PMID- 4146083 TI - Ontogeny of the murine immune system: development of antigen recognition and immune responsiveness. PMID- 4146084 TI - Enzyme changes in experimental biliary obstruction. PMID- 4146085 TI - Inhibition of gastric secretion in man by metiamide: a new, orally active histamine H 2 -receptor antagonist. PMID- 4146086 TI - Pharmacokinetics and azo-link cleavage of salazopyrine in man. PMID- 4146087 TI - Increased susceptibility of splenectomized rats to infection with Diplococcus pneumoniae. PMID- 4146088 TI - Sixteenth International Confederation of Midwives Congress. PMID- 4146089 TI - Clasp repair for removable partial dentures. PMID- 4146090 TI - Assistant doctors--help or hindrance? PMID- 4146091 TI - Vaccination against smallpox. PMID- 4146092 TI - Regulation of aldosterone biosynthesis. PMID- 4146093 TI - The effect of dl-propranolol, d-propranolol and practolol on the hyperactivity induced in rats by prolonged isolation. PMID- 4146094 TI - Steroid 17,20-lyase: the effect of detergents on enzymic activity and microsomal composition. PMID- 4146095 TI - The metabolism of salbutamol in man. PMID- 4146096 TI - Metabolic studies with trans-5-amino-3-(2-(5-nitro-2-furyl)vinyl)-1,2,4-(5- 14 C)oxadiazole (SQ 18,506). 1. Reductive cleavage of the 1,2,4-oxadiazole ring. PMID- 4146097 TI - Management of tardive dyskinesia with thiopropazate. PMID- 4146098 TI - [Polymyopathy and hereditary cardiomyopathy in the Syrian hamster. Selective inhibition of myocardial lesions]. PMID- 4146099 TI - [Gamma-glutamyl transpeptidase values in liver and bile duct diseases. Clinical observations and experimental trials]. PMID- 4146100 TI - Pustular necrotizing angiitis. PMID- 4146101 TI - Influence of light and dark on the free amino acid pattern of the developing chick retina. PMID- 4146102 TI - Perifusion of saurian pancreatic islets and biphasic insulin release following glucose stimulation. PMID- 4146103 TI - Isosmotic adaptation in Myxine glutinosal. II. Variations of the free amino acids, trimethylamine oxide and potassium of the blood and muscle cells. PMID- 4146104 TI - The rate of respiration of mouse brain tissue in physiological and non physiological media as a function of temperature. PMID- 4146106 TI - Thermoregulation in pythons. II. Head-body temperature differences and thermal preferenda in Australian pythons. PMID- 4146105 TI - Factors affecting extracellular space measurements in rabbit detrusor muscle. PMID- 4146107 TI - Effects of constant illumination and hyperoxia on thermal tolerance of goldfish. PMID- 4146108 TI - A comparative study of oxygen toxicity in the retina, brain and liver of the teleost, amphibian and mammal. PMID- 4146109 TI - Blood and liver lipids in torpid and aroused little brown bats, Myotis lucifugus. PMID- 4146110 TI - Iron kinetics in axolotls (Siredon mexicanum). PMID- 4146111 TI - Intestinal peroxisomes in the goldfish (Carassius auratus). PMID- 4146112 TI - Possible role of the arterial chemoreceptors in the ventilatory responses of the anesthetized marmot to changes in inspired P O2 and P CO2 . PMID- 4146113 TI - The control of the interrenal by the pituitary in the elasmobranch, Dasyatis sabina. PMID- 4146114 TI - Comparison of the olfactory response to amino acids in rainbow trout, brook trout, and whitefish. PMID- 4146115 TI - Interaction between hexoses and amino acids for transport in rat small intestine. PMID- 4146116 TI - Diurnal variation in the activity of cholesterol 7 -hydroxylase in the livers of fed and fasted rats. PMID- 4146117 TI - [Some auxiliary documents at the feldsher health centers]. PMID- 4146118 TI - Some pharmacologic characteristics of the human vas deferens. PMID- 4146119 TI - The mitochondrial redox state of rat brain. PMID- 4146120 TI - Effects of convulsants on cortical adenosine triphosphatases. PMID- 4146121 TI - Aromatic amino acid transaminases in rat brain. PMID- 4146122 TI - [Agnes Karll and congress days of 1904]. PMID- 4146123 TI - [Retainer joints]. PMID- 4146124 TI - Panel discussion: the treatment of hypertrophic cardiomyopathy with beta adrenergic blockade. PMID- 4146125 TI - [Changes in the masticatory organs due to traumatic or prosthetic causes]. PMID- 4146126 TI - [Conclusions and recommendations of the 5th congress of ALAFO: 1972]. PMID- 4146127 TI - [Febrile multineuritis with Australia antigen, periarteritis nodosa with Australia antigen (apropos of 2 cases)]. PMID- 4146128 TI - The role of alpha-adrenergic receptor mechanism in ejaculation. PMID- 4146129 TI - Pharmacological behavior of the submaxillary gland and its vasculature of the dog. PMID- 4146130 TI - Paracrystalline formation in cells infected by adenovirus type 12. PMID- 4146131 TI - [Studies on bovine staphylococci of various geographical origins]. PMID- 4146132 TI - [May resistance to methicillin of Staphylococcus aureus be ascribed to changes in membrane permeability?]. PMID- 4146133 TI - [Significance of the lipopolysaccharide structure of E. coli for the transmission of R-factors]. PMID- 4146134 TI - [7 new strains of salmonella subgenus I and 4 serological variants of known types belonging to subgenus I]. PMID- 4146135 TI - [Classification and differential diagnosis of the Klebsiella group with special reference to the so-called oxytocum types]. PMID- 4146136 TI - [Bordetella pertussis spheroplasts. 3. Isolation and chemical analysis of spheroplast cell walls]. PMID- 4146137 TI - Further investigations on the fine structure of coxiella burneti. PMID- 4146138 TI - [Mode of action of ionic surface-active compounds in bacteria. 3. Light and electron microscopy studies on the effect of dimethylaminoacetic-acid dodecylamide chlorbenzylate (DADCl) on mycobacteria]. PMID- 4146140 TI - A sudden decrease in the lipid content of Mycobacterium bovis BCG and Mycobacterium microti MP. A preliminary communication. PMID- 4146139 TI - [Demonstration of IgM-antitoxoplasma antibodies in acute and chronic acquired human toxoplasmosis]. PMID- 4146141 TI - A comparative evaluation of Baird-Parker's ETGPA- and the KRANEP-medium for the selective enumeration of Staphylococcus aureus in foods. PMID- 4146142 TI - Studies on the role of the central and autonomic nervous systems in the toxicity of 5-hydroxytryptamine in anaesthetized rats. PMID- 4146143 TI - Essentiality of coenzyme Q for the oxidation of -glycerophosphate by pig brain mitochondria. PMID- 4146144 TI - Oxidative reactions in the formation of an aldehyde group in the biosynthesis of aldosterone. PMID- 4146145 TI - Palmityl-CoA and palmitylcarnitine interactions in mitochondrial fatty acid elongation. PMID- 4146146 TI - Microsomal electron transport. I. Reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase and cytochrome P-450 as electron carriers in microsomal NADPH-peroxidase activity. PMID- 4146147 TI - Yeast mutants pleiotropically impaired in the regulation of the two glutamate dehydrogenases. PMID- 4146148 TI - The role of NADPH-cytochrome b 5 reductase in microsomal lipid peroxidation. PMID- 4146149 TI - Binding of active and inactive hemolytic factor of sea anemone nematocyst venom to red blood cells. PMID- 4146150 TI - Further data on the specificity of aequorin luminescence to calcium. PMID- 4146151 TI - An iron sulfur protein in the mitochondrial outer membrane, reducible by NADH and NADPH. PMID- 4146152 TI - Studies on plasma membranes. XIX. Isolation and characterization of a plasma membrane fraction from calf thymocytes. PMID- 4146153 TI - Action of several -adrenoceptor blocking drugs in the pregnant sheep and foetus. AB - 1. The effect of several beta-adrenoceptor blocking drugs on the pregnant ewe and foetus were studied. Bunolol, butidrine, oxprenolol, propranolol and USVP65-24 all crossed the ovine placenta and produced a beta-adrenoceptor blockade in the ovine foetus. AH3474, AY21011 and sotalol did not cross the ovine placenta as assessed by the absence of a beta-blockade in the foetus when these compounds were administered to the pregnant ewe.2. Of the beta-blocking compounds tested, only propranolol and oxprenolol produced a prolonged blockade in the foetus. The beta-blockade with propranolol was of 3 h duration in the ewe and 10 h duration in the foetus. Oxprenolol produced a beta-blockade of 3 h duration in the ewe and 8 h in the foetus.3. The beta-blocking drugs which did cross the ovine placenta were more soluble in organic solvents (ether, chloroform, corn oil and olive oil) than those which did not cross the ovine placenta. PMID- 4146154 TI - Cinnamate-4-hydroxylase in Polyporus hispidus. PMID- 4146155 TI - Effect of adrenalectomy and of adrenocortical hormones on RNA turnover in a variety of subcellular fractions of rat liver. PMID- 4146156 TI - Podiatry assistants in the neighborhood health center. PMID- 4146157 TI - Iodinating ability of various leukocytes and their bactericidal activity. AB - A rapid method that employs monolayers of different phagocytic cells, primarily from guinea pigs and mice, has allowed a kinetic determination of (a) ingestion by these cells of labeled particles, (b) fixation of (131)I and (c) microbicidal activity in the cells after periods as short as 5' of exposure of bacteria to phagocytes. Phagocytes so examined included polymorphonuclear leukocytes (PMN) elicited into the peritoneal cavity, elicited peritoneal mononuclear cells (monocytes) (MN), and peritoneal macrophages (MAC) obtained simply by lavage. Circulating PMN from normal human subjects and from children afflicted with chronic granulomatous disease were also studied. The potential for generation of H(2)O(2) (a key component of the iodinating system) of all the normal cells studied, gauged by their content of cyanide-insensitive NADH oxidase, seemed comparable. Peroxidase levels varied widely, and were highest in PMN and almost undetectable in MAC. Catalase was at negligible levels in all the cell types obtained from mice. The fixation of (131)I by phagocytes ingesting (14)C-labeled dead tubercle bacilli appeared to be primarily a function of the cellular peroxidase content. Thus, mouse macrophages, with virtually no peroxidase, displayed no fixation of iodide. PMN proved far more able to fix (131)I during phagocytosis than did MN. In experiments comparing PMN from normal human subjects and from children with chronic granulomatous disease (CGD), a sex-linked condition characterized by a deficiency of H(2)O(2) production during phagocytosis and low microbicidal activity, the iodination ratio of CGD cells was dramatically less than that of normal PMN (by about two orders of magnitude). Capacity for iodination was correlated with bactericidal activity toward E. coli. At low bacterial loads (ca. 5:1), phagocytes killed efficiently, and little discrepancy in ability among cell types was apparent. Under the stress of higher loads of (14)C-labeled E. coli (ca. 100:1), differences in bactericidal activity were exaggerated, and a substantial disparity between MN and PMN was observed in favor of the latter. The hierarchy for killing efficiencies therefore agreed with that for iodination, with one notable exception: mouse MAC were consistently competent in their killing activity, more so than MN, even though they virtually lack peroxidase and the ability to iodinate ingested bacteria. PMID- 4146158 TI - Electrophysiology of cardiac function in teleosts: cholinergically mediated inhibition and rebound excitation. AB - 1. A study has been made on the responses of the plaice (Pleuronectes platessa) heart, isolated and in situ to differential vagal stimulation using intra- and extracellular recording electrodes. The effects of direct application of acetylcholine and catecholamines and their respective blocking agents are also reported.2. Vagal stimulation at 7 Hz totally inhibits heart beat whilst stimulation at 2-3 Hz accelerates it. Both these effects are blocked by atropine (10(-6) g/ml.). Bretylium (10(-5) g/ml.) and pronethalol (10(-6) g/ml.) have no effect upon either response to vagal stimulation.3. On cessation of prolonged inhibitory vagal stimulation there is a marked increase in the heart rate, and in quiescent hearts one or two beats are initiated after stimulation.4. Vagal stimulation gives rise to a hyperpolarization in atrial cells. It is proposed that all the excitatory effects of vagal stimulation are due to rebound excitation from an inhibitory hyperpolarization. At high frequencies the hyperpolarizations summate to give rise to total inhibition. At lower frequencies of stimulation the heart beat is increased to rates dependent on interaction between the time course of the hyperpolarization and the refractory period of the heart. Both effects are cholinergically mediated.5. The rebound excitation in response to vagal stimulation (post-vagal tachycardia) persists in response to stimulation of the atrial myocardium in the presence of atropine (10(-6) g/ml.) and bretylium (10(-5) g/ml.). It is therefore suggested that this is a response of the muscle cell membrane to vagal stimulation and is not nerve-mediated. PMID- 4146159 TI - [The state of the sympathetic-adrenal system in congestive heart failure]. PMID- 4146160 TI - [The effect of mental work with different degrees of nervous-emotional stress on the cardiovascular system]. PMID- 4146161 TI - [Long-term control of the bioelectrical activity of the human heart in earthside experiments and in space flight]. PMID- 4146162 TI - [Microflora of the sealed cabin in a 3-day manned experiment at reduced temperature and high relative humidity]. PMID- 4146163 TI - [Australia antigen. Current status of knowledge of it]. PMID- 4146164 TI - Characteristic changes of vascular adrenergic reactions in diabetes mellitus. PMID- 4146165 TI - Involvement of 3',5'-cyclic adenosine monophosphate in the increase of tyrosine hydroxylase activity elicited by cold exposure. PMID- 4146166 TI - Changing aspects of the etiology and treatment of pleural empyema. PMID- 4146167 TI - Direct action of methoxamine on the isolated heart muscle. PMID- 4146168 TI - Induction of unresponsiveness to skin and heart allografts in mice by a synergistic treatment with procarbazine, antilymphocyte serum, and donor-type cells. PMID- 4146169 TI - Graft-versus-host reaction in the rat popliteal lymph node. PMID- 4146170 TI - The immunological status of rats with long surviving (enhanced) kidney allografts. PMID- 4146171 TI - The duodenal microflora in relation to various symptoms and manifestations in patients with extrahepatic biliary disease. PMID- 4146173 TI - Placental transmission and maternal and neonatal elimination of fluroxene. PMID- 4146172 TI - Red-cell 2,3-diphosphoglycerate in surgical correction of cyanotic congenital heart disease. PMID- 4146174 TI - [Immunotherapy in the treatment of allergic and bacterial diseases of the upper respiratory tract]. PMID- 4146175 TI - The effects of ganglion blocking agents on the isolated, innervated bladder of the guinea-pig. PMID- 4146176 TI - Human lingual pit caries: distribution between right and left maxillary incisors. PMID- 4146177 TI - Multiple biochemical effects of a series of x-ray induced mutations at the albino locus in the mouse. PMID- 4146178 TI - Stimulation tests of pituitary-Leydig cell function in normal male subjects and hypogonadal men. PMID- 4146179 TI - Gonadotrophin test of the functional capacity of Leydig cells in normal and hypogonadal boys. PMID- 4146180 TI - Enzymes in facultative anaerobiosis of molluscs. I. Malic enzyme of oyster adductor muscle. PMID- 4146181 TI - Properties of ribonucleoside diphosphate reductase in nucleotide-permeable cells. AB - Ribonucleoside diphosphate (RDP) reductase activity can be readily assayed in ether-treated Escherichia coli cells. The rate of cytidine 5'-diphosphate (CDP) reduction observed in ether-treated cells by using saturating substrate concentrations is about 25% of the rate of de novo deoxyribonucleotide synthesis required to account for in vivo deoxyribonucleic acid synthesis. Optimal activity is observed in the presence of magnesium ions and a positive effector. Adenosine 5'-triphosphate (ATP), deoxy ATP (dATP), and deoxythimidine triphosphate serve as positive effectors, and dATP also serves as a negative effector. These effects on the activity in ether-treated cells resemble those observed in vitro with highly purified enzyme. When the RDP reductase activity in these cells is assayed by using high specific activity (3)H-CDP as substrate, even at nonsaturating substrate concentrations, the sensitivity of the assay is sufficient to make it useful for the assay of the low levels of reductase activity in cells not derepressed by thymine starvation or in cells containing mutationally altered RDP reductase. This assay is much easier to perform than the usual in vitro assay, since thioredoxin, thioredoxin reductase, and enzyme subunits B1 or B2 need not be first purified and added to the reaction mixtures. PMID- 4146182 TI - Mechanisms of energy conservation in the mitochondrial membrane. PMID- 4146183 TI - Microwave Hall mobility measurements on heavy beef heart mitochondria. PMID- 4146184 TI - A multiple role for the coenzyme in the mechanism of action of 6-phosphogluconate dehydrogenase. The oxidative decarbosylation of 2-deoxy-6-phosphogluconate. PMID- 4146185 TI - Soluble, membrane-bound, and detergent-solubilized rat striatal tyrosine hydroxylase. pH-dependent cofactor binding. PMID- 4146186 TI - Biosynthesis of pyridine nucleotides in early embryos of the mouse (Mus musculus). PMID- 4146187 TI - Pyridine nucleotide metabolism in Escherichia coli. II. Niacin starvation. PMID- 4146188 TI - Pyridine nucleotide metabolism in Escherichia coli. 3. Biosynthesis from alternative precursors in vivo. PMID- 4146189 TI - Pyridine nucleotide metabolism in Escherichia coli. IV. Turnover. PMID- 4146190 TI - Studies on adrenal steroid hydroxylases. Complex formation of the hydroxylase components. PMID- 4146191 TI - Ultrastructure of Morris renal tumors. PMID- 4146192 TI - Comparative diagnostic abilities of child health associate interns and practicing pediatricians. PMID- 4146193 TI - Effect of additives on the kinetics of interconversion of sulphamethoxydiazine crystal forms. PMID- 4146194 TI - Determination of the thermodynamics of the methyl group in solutions of drug molecules. PMID- 4146195 TI - Interference of alkanes in the gas chromatographic analysis of cannabis products. PMID- 4146196 TI - Measurement of dissolution rates of potassium chloride from various slow release potassium chloride tablets using a specific ion electrode. PMID- 4146197 TI - The effect of pore size of the inhaler support upon the concentration of volatile drug emerging in the air stream from a nasal inhaler. PMID- 4146198 TI - Sound-withdrawal hypertension in rats--a new form of experimental hypertension. PMID- 4146199 TI - Evidence for a difference in mechanism of action between fenfluramine- and amphetamine-induced anorexia. PMID- 4146200 TI - The adrenoceptors mediating catecholamine effects in frog isolated skin. PMID- 4146201 TI - Effect of inosine on guinea-pig bronchial muscle. PMID- 4146203 TI - Application of orthogonal functions to correct for quadratic irrelevant absorption in spectrophotometric analysis. PMID- 4146202 TI - Relaxation of intestinal smooth muscle and calcium movements. PMID- 4146204 TI - Increased dopamine concentration in the striatum in the mouse by FLA-63, a dopamine- -hydroxylase inhibitor. PMID- 4146205 TI - Inhibition of the anticonvulsant activity of L-dopa by FLA-63, a dopamine- hydroxylase inhibitor. PMID- 4146206 TI - On the blockade of neural and exogenous noradrenaline. PMID- 4146207 TI - Sodium salicylate toxicity and pregnancy in mice. PMID- 4146208 TI - Factors influencing the response of the mouse vas deferens preparation to noradrenaline. PMID- 4146209 TI - Norphenazone, a new metabolite of phenazone in human urine. PMID- 4146210 TI - Effects of intracerebral injections of 6-hydroxydopamine on sleep and waking in the rat. PMID- 4146211 TI - Lorazepam on visuo-motor co-ordination and visual function in man. PMID- 4146212 TI - Nutritional circulation in the heart. IV. Effect of calcium chloride and potassium chloride on myocardial hemodynamics and clearance of 86 rubidium. PMID- 4146213 TI - Propranolol and practolol in the treatment of spontaneous angina pectoris. PMID- 4146214 TI - Human regulatory gene for inducible tyrosine aminotransferase in rat-human hybrids. AB - The inducibility of tyrosine aminotransferase (EC 2.6.1.5) by corticosteroid hormones in rat-human hybrid clones was studied. The presence of human X chromosome activity in the cells was always associated with the suppression of tyrosine aminotransferase inducibility in all the clones examined. Negative correlation between the human X chromosome and inducibility of the enzyme was clearly established. Corticosteroid receptor was present to the same extent in hybrid cell clones that either contained or lost the human X chromosome. The human repressor for inducible tyrosine aminotransferase has a linkage relationship with glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and hypoxanthine-guanine-phosphoribosyltransferase (EC 2.4.2.8) and, therefore, can be assigned to the X chromosome. PMID- 4146215 TI - Prospective in vitro prediction of enhancement of canine renal allografts. PMID- 4146216 TI - The metabolic breakdown of inhalation anaesthetics and their clinical implications. PMID- 4146217 TI - Stimulation of gastric acid secretion by 5-methyl histamine incat. PMID- 4146218 TI - Annually recurrent epidemic polyarthritis and Ross River virus activity in a coastal area of New South Wales. II. Mosquitoes, viruses, and wildlife. PMID- 4146219 TI - An outbreak of Eastern equine encephalomyelitis in Upstate New York during 1971. PMID- 4146220 TI - Enzyme activity of the cytochrome system of the egg and larva of the cattle tick (Boophilus microplus). PMID- 4146221 TI - Cytochrome c enhancement of singlet molecular oxygen production by the NADPH dependent adrenodoxin reductase-adrenodoxin system: the role of singlet oxygen in damaging adrenal mitochondrial membranes. PMID- 4146222 TI - Antilymphocyte serum. An investigation into decay phenomenon. PMID- 4146223 TI - Thioredoxin reductase from rat liver. PMID- 4146224 TI - Phenol hydroxylase from yeast. Purification and properties of the enzyme from Trichosporon cutaneum. PMID- 4146225 TI - Studies on the effect of a thymic humoral factor on differentiation of thymus derived lymphocytes. PMID- 4146226 TI - Crithidia fasciculata: regulation of aerobic fermentation by malic enzyme. PMID- 4146228 TI - Hyperglycemia in acute malathion intoxication in rats. PMID- 4146227 TI - The effect of antilymphocytic antibody on the humoral immune response in different strains of mice. 3. The response to type 3 pneumococcus polysaccharide. PMID- 4146229 TI - The pattern of growth of Clytia johnstoni. PMID- 4146230 TI - Supressor cells in the graft vs host reaction. PMID- 4146231 TI - Retention of graft-vs-host activity in non-adherent spleen cells after depletion of cytotoxic activity by incubation on allogeneic target cells. PMID- 4146232 TI - Effects of isoproterenol, dl-propranolol and d-propranolol on the A-V transmission and the A-V nodal transmembrane action potential. PMID- 4146233 TI - Objective assessment of degree of psychiatric impairment: is it possible? PMID- 4146234 TI - A mutant of Asperigillus nidulans lacking NADP-linked glutamate dehydrogenase. PMID- 4146235 TI - Angiitis in drug users. PMID- 4146236 TI - [General and orthodontic aspects in relation to traumatic anterior teeth]. PMID- 4146237 TI - [Ultrastructural study of "Australia" antigen. II. Morphological analysis of Australia antigen in several pathological states]. PMID- 4146238 TI - [Pneumococci producing beta-hemolysis under the influence of antibiotics]. PMID- 4146239 TI - The effects of anti-inflammatory drugs on vascular exudation evoked by cold injury. PMID- 4146240 TI - [Granulomatous angiitis during rheumatoid arthritis]. PMID- 4146241 TI - The protection against the cerebral and pulmonary effects of hyperbaric oxygen by pharmacological agents and lithium salts in mice. PMID- 4146242 TI - Electron microscopic and enzyme histochemical studies of cerebellum, ocular and skeletal muscles in chronic progressive ophthalmoplegia with cerebellar ataxia. PMID- 4146243 TI - Characterization of viruses (Witwatersrand and Germiston) isolated from mosquitoes and rodents collected near Lunyo Forest, Uganda, in 1968. PMID- 4146244 TI - Ankle-disarticulation: a definitive type of amputation in adults. PMID- 4146245 TI - The effect of fluroxene on intracranial pressure in patients with intracranial space-occupying lesions. PMID- 4146246 TI - A look to the future. PMID- 4146247 TI - Effect of premedication on duration of anesthesia with halogenated vapours: chloroform, trichlorethylene, halothane, methoxyflurane, enflurane (Ethrane) and isoflurane (forane). PMID- 4146248 TI - Inhibition of the effect of oxytocin by methoxyflurane in vitro. PMID- 4146249 TI - The effect on dental caries of weekly rinsing with a neutral sodium fluoride or an acidulated phosphate-fluoride mouthwash. PMID- 4146250 TI - Concentrations of gentamicin and carbenicillin in bronchial secretions. PMID- 4146251 TI - Studies on the stereospecificity of closely related compounds which block postganglionic acetylcholine receptors in the guinea-pig ileum. PMID- 4146252 TI - Synthesis of some N-substituted eleostearic acid hydrazides as potential monoamine oxidase inhibitors. PMID- 4146253 TI - Selectivity in new -adrenergic blocking agents. (3-Amino-2 hydroxypropoxy)benzamides. PMID- 4146254 TI - Derivative of 3,4-dihydro-1(2H)-naphthalenone as -adrenergic blocking agents. 3. Carbonyl-containing analogs of bunolol. PMID- 4146255 TI - [Action of ganglioplegics on duodenal peristalsis propagation]. PMID- 4146256 TI - [Ventilatory responses of fish to various doses of catecholamines: the role of alpha and beta effects in the seasonal variations of responsiveness]. PMID- 4146257 TI - [Treatment of the asthmatic state. Current status (apropos of 18 cases)]. PMID- 4146258 TI - [Treatment of psychogenic sleep disorders]. PMID- 4146259 TI - [Comparative study of the antipsychotic action of certain neuroleptics modeled on LSD psychosis]. PMID- 4146260 TI - An oral health survey of Aborigines and Torres Strait Islanders in far North Queensland. PMID- 4146261 TI - Adrenergic mechanisms in the cerebral vascular bed. PMID- 4146262 TI - An improved method for the study of reagin-mediated mast cell degranulation in rats. PMID- 4146263 TI - Regulation of tyrosine aminotransferase in rat liver. X. Characterization and interconversion of the multiple enzyme forms. PMID- 4146264 TI - Regulation of tyrosine aminotransferase in rat liver. XI. Studies on the relationship of enzyme stability to enzyme turnover in cultured hepatoma cells. PMID- 4146265 TI - Specific basic proteins from mammalian testes. Isolation and properties of small basic proteins from rat testes and epididymal spermatozoa. PMID- 4146266 TI - Properties of chorismate synthase in Neurospora crassa. PMID- 4146267 TI - 3-Hydroxy-3-methylglutaryl coenzyme A reductase. Solubilization and purification of a cold-sensitive microsomal enzyme. PMID- 4146268 TI - Electrophysiological and antiarrhythmic effects of 4-(2-hydroxy-3 isopropylaminopropoxy)-indole (LB-46) on the canine cardiac cells. PMID- 4146269 TI - Reaction of antiarrhythmic agents with aglycones and erythrophleum alkaloids. PMID- 4146270 TI - Antiarrhythmic potency of N-propyl ajmaline with untoward response of ventricular fibrillation in excess dose. PMID- 4146271 TI - Drug therapy for the reduction of gastric acid secretion. PMID- 4146272 TI - Preparations for morning sickness. PMID- 4146273 TI - Transplantation immunity evoked by skin homografts and expressed in intact skin. PMID- 4146274 TI - An analysis of epidermolysis in hamsters suffering from homologous disease. PMID- 4146275 TI - Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N oxidation, N-oxide reduction, and N-oxide N-dealkylation. II. N,N dimethylaniline. PMID- 4146276 TI - Preperitoneal repair of inguinal hernias in infancy and childhood. PMID- 4146277 TI - The bacterial degradation of flavonoids. Hydroxylation of the A-ring of taxifolin by a soil pseudomonad. AB - Cell-free extracts prepared from a Pseudomonas sp. grown on (+)-catechin oxidized taxifolin in the presence of NAD(P)H and molecular oxygen. The enzyme catalysing the reaction was partially purified and shown to be a flavoprotein. The product was identified as 3',4',5,7,8-pentahydroxyflavanonol (dihydrogossypetin). PMID- 4146278 TI - Conversion of p-coumarate into caffeate by Streptomyces nigrifaciens. Purification and properties of the hydroxylating enzyme. AB - 1. An enzyme responsible for the conversion of p-coumarate into caffeate was purified 97-fold from Streptomyces nigrifaciens. The enzyme had a molecular weight of 18000 as determined by Sephadex G-100 gel filtration and was homogeneous on polyacrylamide-gel electrophoresis. 2. The preparation exhibited both p-coumarate hydroxylase and caffeate oxidase activities. 3. Stoicheiometry of the reaction indicated a mono-oxygenase-mediated catalysis consuming 1mol of O(2)/mol of substrate hydroxylated. 4. NADH, NADPH, tetrahydropteroylglutamate or ascorbate act as electron donors for the reaction, ascorbate being inhibitory at higher concentrations. 5. The optimum enzyme activity was at about pH7.7 and 40 degrees C, with an activation energy of 39kJ/mol. 6. Monophenols such as p hydroxyphenylpropionate, p-hydroxyphenylacetate, l-tyrosine and dl-p hydroxyphenyl-lactate were also hydroxylated by the preparation, in addition to p coumarate. 7. The enzyme was a copper protein having 0.38% copper in a bound form. 8. Thiol-group inhibitors did not affect the reaction. 9. The relationship of the enzyme to other hydroxylases is discussed. PMID- 4146279 TI - Amino acid sequence of the N-terminal sixty-nine residues of heavy chain derived from a homogeneous rabbit antibody. AB - The sequence of the N-terminal 69 residues of heavy chain from a homogeneous rabbit antibody to type III pneumococcal polysaccharide was determined. The sequence is similar to that found in heavy chains of normal pooled rabbit immunoglobulins of the same allotype Aa1. Two regions of the homogeneous heavy chain (residues 35-46 and 62-69) are very similar to corresponding regions of heavy chains from rabbit Aa2 immunoglobulin, as well as from mouse, guinea-pig and human immunoglobulins. In contrast, residues 47-62 appear to be variable. Comparison in this section with another homogeneous anti-pneumococcal antibody (Strosberg et al., 1972) of related specificity and of the same allotype indicates sequence variation in at least three positions. An antibody to group C streptococcal carbohydrate of allotype Aa2 (Fleischman, 1971) differs by five amino acids in the same region of the heavy chain. Sequence variability between these three antibodies does not occur in homologous positions within this variable section. Allotype-related sequences could not be identified in section 34-65. PMID- 4146281 TI - Inhibition of erythropoiesis in the spleens of irradiated mice injected with allogeneic lymphocytes. Reactivity of lymphocytes aganist non-H-2 transplantation antigens. PMID- 4146280 TI - Haemodynamic effects of a new beta-blocking agent 'Sectral' (M & B 17803A). PMID- 4146282 TI - Biogenic amines and endocrine function. Introduction: neuroendocrine transducers and monoamines. PMID- 4146283 TI - Control of epinephrine synthesis and secretion. PMID- 4146286 TI - Ambulance service. PMID- 4146284 TI - Biogenic amines, sympathetic nerves, and renin secretion. PMID- 4146287 TI - [Experimental study of an inanimate movement response as a conflict index in the Rorschach test]. PMID- 4146288 TI - Clearance of foreign red cells from the blood of aging mice. PMID- 4146289 TI - Idiosyncracies of parathyroid hyperfunction. PMID- 4146290 TI - Regulation of insect populations by protozoa and nematodes. PMID- 4146291 TI - Phosphonoprotein. Characterization of aminophosphonic acid rich glycoproteins from sea anemones. PMID- 4146292 TI - An enzymic reduction system for metmyoglobin and methemoglobin, and its application to functional studies of oxygen carriers. PMID- 4146293 TI - Influence of nicotinamide and pyridine nucleotides on streptozotocin and alloxan induced pancreatic B cell cytotoxicity. PMID- 4146294 TI - Insulin metabolizing enzyme activities in human placental tissue. PMID- 4146295 TI - Iron-dependent loss of liver cytochrome P-450 haem in vivo and in vitro. PMID- 4146296 TI - NADP specific dihydroxyacetone reductase from Dunaliella parva. PMID- 4146297 TI - Antibodies to plant ferredoxin. PMID- 4146299 TI - Medicine: the learned--and learning--profession. PMID- 4146298 TI - Respiratory protection of nitrogenase in Azotobacter vinelandii. PMID- 4146300 TI - Which are witch? PMID- 4146302 TI - Migrant health care--an attempt to meet the problem. PMID- 4146301 TI - VD an equal opporunity destroyer. PMID- 4146303 TI - National cooperative study of hepatitis B antibody treatment of antigen-positive fulminant hepatitis: first randomized case in Illinois. PMID- 4146304 TI - EKG of the month: Junctional premature beat. PMID- 4146305 TI - Ectopic hydroureter. PMID- 4146306 TI - Ruptured spleen. PMID- 4146307 TI - Emergency department physician staffing patterns and residency training. PMID- 4146308 TI - Colerectal adenomas and adenocarcinomas. PMID- 4146309 TI - Medicine in 1900. The physician as the guardian of the public health and his contributions to charity. PMID- 4146310 TI - Study of serum acid phosphatase in children with kidney diseases. PMID- 4146311 TI - A commentary on "Current Studies on Schizophrenia". PMID- 4146312 TI - Multiplication of viruses isolated from arthopods and vertebrates in Australia in experimentally infected mosquitoes. PMID- 4146313 TI - Field studies using wide-mesh mosquito bed nets in Taiwan and Indonesia. PMID- 4146314 TI - The presence of a peritrophic membrane in pupal mosquitoes (Diptera: culicidae). PMID- 4146315 TI - A comparison of the neural regulation of tyrosine hydroxylase activity in sympathetic ganglia of adult mice and rats. PMID- 4146317 TI - The oxidation of 6-hydroxydopamine. PMID- 4146316 TI - Feedback regulation of 5-HT synthesis in rat striatal slices. PMID- 4146318 TI - The estimation of acetylsalicylic acid and salicylate in biological fluids by gas liquid chromatography. PMID- 4146319 TI - Rapid gas-liquid chromatographic estimation of antipyrine in plasma. PMID- 4146320 TI - A circular dichroic investigation of the binding of fenoprofen, 2(3 phenoxyphenyl)-propionic acid, to human serum albumin. PMID- 4146321 TI - Further studies on the adrenergic neuron blocking activity of some -adrenoceptor antagonists and guanethidine. PMID- 4146322 TI - Analysis of the effects of apomorphine and bulbocapnine in relation to the proposed dopamine receptor. PMID- 4146323 TI - Polyphloretin phosphate temporarily potentiates prostaglandin E 2 on the rat fundus, probably by inhibiting PG15-hydroxydehydrogenase. PMID- 4146324 TI - The pharmacokinetics of phentermine and chlorphentermine in chronically treated rats. PMID- 4146325 TI - Oscillatory testing of o-w emulsions containing mixed emulsifers of the surfactant-long chain alcohol type: self-bodying action. PMID- 4146326 TI - Hydrophilic-lipophilic balance and partial molal volume of non-ionic surfactants. PMID- 4146327 TI - Prediction of systemic availability from plasma-level data after oral drug administration. PMID- 4146328 TI - A comparison of the pore structure of tablets prepared from force screened and comminuted granules. PMID- 4146329 TI - The influence of synthetic "substance P" on tremor caused by LSD in mice. PMID- 4146330 TI - Modification by caerulein of action potential activity in circular smooth muscle of isolated small intestine. PMID- 4146331 TI - On the question of subclassification of -adrenoceptors. PMID- 4146332 TI - Evidence for carrier-mediated efflux of noradrenaline from the axoplasm of adrenergic nerves in rabbit atria. PMID- 4146333 TI - Differential effects on mouse brain catecholamine turnover of chlorpromazine, trifluoperazine and closely-related non-tranquillizing analogues. PMID- 4146334 TI - The absorption and distribution of isopropamide iodide in the rat. PMID- 4146335 TI - Stereospecific requirements for hallucinogenesis. PMID- 4146336 TI - Comparison of dental surveys in Elmira and Corning, New York. PMID- 4146337 TI - Polyarthritis induced in the rat with cell walls from several bacteria and two Streptomyces species. PMID- 4146338 TI - Well-women. PMID- 4146340 TI - Differential certification of physician's assistants. PMID- 4146339 TI - Incisor caries and primary school tuckshops. PMID- 4146341 TI - The role of a regional surgical society. PMID- 4146342 TI - Stoichiometry of reduction and phosphorylation during illumination of intact chloroplasts. PMID- 4146343 TI - EPR studies on phosphorylating particles from Azotobacter vinelandii. PMID- 4146344 TI - Antimycin-insensitive mutants of Candida utilis. I. Isolation and characterization of mutant 28. PMID- 4146345 TI - [Clinical picture, physiopathology and therapy of the pulmonary edema]. PMID- 4146346 TI - [Rheumatic and pararheumatic diseases. Problems of diagnosis and therapy]. PMID- 4146347 TI - California encephalitis virus endemicity in the Yukon Territory, 1972. AB - Sera from 218 of 1574 (14%) small mammals collected in the Yukon Territory between 14 May and 13 August 1972 neutralized a Yukon strain of California encephalitis virus (snowshoe-hare subtype). These included 133 of 319 (42%) snowshoe hares (Lepus americanus), 84 of 1243 (7%) ground squirrels (Citellus undulatus) and 1 of 12 (8%) tree squirrels (Tamiasciurus hudsonicus). California encephalitis virus (snow-shoe hare subtype) was isolated from four pools of unengorged Aedes communis mosquitoes collected near Whitehorse (61 degrees N., 135 degrees W.) and on one occasion each from pools of the same species collected at Hunker Creek (64 degrees N., 138 degrees W.) and at mile 125, Dempster Highway (66 degrees N., 138 degrees W.) during July 1972. Replication of a Yukon strain of California encephalitis virus was observed in wild-caught Culiseta inornata and Aedes canadensis mosquitoes after intrathoracic injection and holding at temperatures of 80 degrees , 50 degrees and 40 degrees F. PMID- 4146348 TI - Role of bacterial endotoxin in the graft-vs.-host syndrome. PMID- 4146349 TI - Possible role of endotoxemia during immunologic imbalance. PMID- 4146350 TI - The future of the United States space program. The 1973 Harvey Cushing oration. PMID- 4146351 TI - Relief of postherpetic neuralgia with psychotropic drugs. PMID- 4146352 TI - Growth and metabolism of rats fed nonprotein nitrogen diets supplemented with nicotinamide, succinate and pyridoxine. PMID- 4146353 TI - Evaluation of electrical pulses and elevated levels of potassium ions as stimulants of adenosine 3', 5'-monophosphate (cyclic AMP) accumulation in guinea pig brain. PMID- 4146354 TI - Effects of hormones, prostaglandins and cyclic-AMP on the synthesis of progesterone by the human placenta in vitro. PMID- 4146356 TI - [Antibiotics and chemotherapy of enterogenous urticarias]. PMID- 4146355 TI - [Cadaver kidney homologous transplant. Clinical results in 64 patients]. PMID- 4146357 TI - [Beta-adrenergic block and ventilatory function. Clinical aspects]. PMID- 4146358 TI - Treating problem children with stimulant drugs. PMID- 4146359 TI - Risks vs. benefits of antipsychotic drugs. PMID- 4146360 TI - [Clinical value of blood enzyme determination in the diagnosis of myocardial infarct]. PMID- 4146361 TI - The role of beta adrenoceptors in the coronary and systemic hemodynamic responses to emotional stress in conscious dogs. PMID- 4146362 TI - Practolol in treating tachyarrhythmias. PMID- 4146363 TI - Physiological and pharmakological influences on orthostasis. PMID- 4146364 TI - The role of ABO blood groups in blood rheology of cardiovascular disorders. PMID- 4146365 TI - Drugs ingested by pregnant women. PMID- 4146366 TI - Drug metabolism by placenta. PMID- 4146368 TI - Antimicrobial agents--mechanisms of action and clinical usage. PMID- 4146367 TI - A microsomal enzyme inhibitor in the gut contents of the house cricket (Acheta domesticus). PMID- 4146369 TI - [Diphenylhydantoin in children. Clinico-pharmacological studies]. PMID- 4146370 TI - Purification & properties of a soluble reduced nicotinamide adenine dinucleotide (NADH) dehydrogenase from Agrobacterium tumefaciens. PMID- 4146371 TI - Protein deficiency & regional chemistry of the brain. II. Effects of protein deficiency on regional distribution of enzymes of glutamate metabolism in rat brain. PMID- 4146372 TI - Purification and properties of beef liver D-glycerate dehydrogenase. PMID- 4146373 TI - Effects of Triton X-100 on drug hydroxylation system of rat liver microsomes induced by phenobarbital or 3-methylcholanthrene. PMID- 4146374 TI - Identity of the rapidly appearing purple intermediate of D-amino acid oxidase. PMID- 4146375 TI - The early stage of labeling of microsomal membrane proteins in rat liver by radioactive amino acids. PMID- 4146376 TI - [Effect of 1-(4-oxyphenyl)-1-oxy-2-n-butylaminoethane sulfate on peripheral vascular diseases]. PMID- 4146377 TI - [Physiopathological findings in the cosmonauts of the Apollo 14 space mission]. PMID- 4146378 TI - Effects of interferon on leukaemia virus activation in graft versus host disease. PMID- 4146379 TI - Glutamine synthetase induction in embryonic neural retina: immunochemical identification of polysomes involved in enzyme synthesis. AB - Glutamine synthetase (EC 6.3.1.2) in embryonic neural retina in culture is rapidly induced by hydrocortisone. Retina polysomes involved in translation of this enzyme were precipitated with a high degree of specificity by the gammaglobulin isolated from antiserum against the enzyme (anti-enzyme gammaglobulin). Using immunoprecipitation procedures, we determined that the amount of polysome-bound nascent enzyme was maximal in polysomes comprising 9-14 ribosomes and was about 3-fold higher in the induced than in the noninduced retina. Within this size group of polysomes, those comprising 11-13 ribosomes showed consistently greater binding of anti-enzyme [(125)I]gammaglobulin than of normal [(125)I]-gammaglobulin. This size of polysomes corresponds to that calculated for a monocistronic messenger RNA for the subunit of this enzyme, which has a molecular weight of 42,000. The application of immunochemical techniques to identification of templates for synthesis of an enzyme in embryonic cells that constitutes less than 1% of the total cellular proteins indicates the usefulness of this method for detailed studies on regulation of other quantitatively minor products significant in cell differentiation. PMID- 4146380 TI - Biotransformation of drugs used in anesthesia. PMID- 4146381 TI - Effect of anesthetics on mitochondrial function. PMID- 4146382 TI - Hepatic microsomal enzyme induction. PMID- 4146383 TI - Anesthesia and hepatic metabolism: current concepts of carbohydrate homeostasis. PMID- 4146384 TI - Inhalation anesthetics and myocardial metabolism: possible mechanisms of functional effects. PMID- 4146385 TI - The dental health of five-year-old children of different ethnic origins resident in an inner Birmingham area and a nearby borough. PMID- 4146386 TI - Antibodies to teichoic acids in man. PMID- 4146387 TI - Alterations in enzyme activity and hyperexcitability in the chronic undercut cerebral cortex of monkey. PMID- 4146388 TI - [Antiallergic action of peppermint oil azulene]. PMID- 4146389 TI - Papaver bracteatum Lindl.--a new plant source of opiates. PMID- 4146390 TI - The central and peripheral activities of anti-acetylcholine drugs. Some concepts of practical relevance. PMID- 4146391 TI - Intestinal absorption, intestinal distribution, and excretion of (14C) labelled hyoscine N-butylbromide (butylscopolamine) in the rat. PMID- 4146392 TI - Serum and blood concentration of sodium cephalexin in man given single intramuscular and intravenous injections. PMID- 4146393 TI - Gas-liquid chromatographic separation of the optical isomers of some "ephedrines" and "pseudoephedrines". PMID- 4146394 TI - An examination of acid-base equilibria of 1,4-benzodiazepines by spectrophotometry. PMID- 4146395 TI - Oscillatory testing of o-w emulsions containing mixed emulsifiers of the surfactant-long chain alcohol type: influence of surfactant chain length. PMID- 4146396 TI - The effect of pH and of temperature on the stability and bioactivity of nystatin and amphotericin B. PMID- 4146397 TI - Anti-inflammatory activity in human plasma. PMID- 4146399 TI - Dopa reversal of hypoxia-induced disruption of the conditioned avoidance response. PMID- 4146398 TI - Effect of ergot drugs on central catecholamine neurons: evidence for a stimulation of central dopamine neurons. PMID- 4146400 TI - Abnormal O-methylated dopamine metabolites: the endogenous toxins of schizophrenia or parkinsonism? PMID- 4146401 TI - Blood-brain barrier to carbidopa (MK-486) and Ro 4-4602, peripheral dopa decarboxylase inhibitors. PMID- 4146402 TI - A note on the effect of (+)- and (-)-amphetamine on lipid metabolism. PMID- 4146403 TI - Salivary excretion of paracetamol in man. PMID- 4146404 TI - The demethylation of methamphetamine by intestinal microflora. PMID- 4146405 TI - Hyperthermia and the amphetamine aggregation phenomenon: absence of a causal relation. PMID- 4146406 TI - In vitro metabolism of neostigmine and pyridostigmine. PMID- 4146407 TI - The influence of starch and lactose on the release rates of drugs from hard gelatin capsules. PMID- 4146408 TI - [Apollo 15]. PMID- 4146409 TI - [Disaster of the Soyuz 11. Space medical aspects]. PMID- 4146410 TI - [Effect of polyinosinic-polycytidylic acid on humoral and cellular immunological reactions]. PMID- 4146411 TI - Polyarteritis in the dog: a case report. PMID- 4146412 TI - [The blood clotting system in infarcts of the internal organs and peripheral gangrene in children with periarteritis nodosa]. PMID- 4146413 TI - [Portal hypertension syndrome. Pathogenesis, diagnosis, indications, surgical treatment, complications]. PMID- 4146414 TI - [Fracture of the navicular bone and its significance in accident medicine]. PMID- 4146417 TI - The employment of frozen sections in cancer diagnosis. PMID- 4146415 TI - Some contributions of molecular biology to the question of viral carcinogenesis. PMID- 4146416 TI - Cell division and disseminated neoplastic disease in man: a review. PMID- 4146418 TI - Modern trends in the prevention of cancer recurrence. PMID- 4146419 TI - The follow-up of the cancer patient. PMID- 4146420 TI - Certain aspects of cancer control and the treatment of malignant tumors in the USSR. PMID- 4146421 TI - Importance of the preoperative cancer evaluation. PMID- 4146422 TI - The TNM-system. PMID- 4146423 TI - Recent acquisitions in nuclear medicine for the detection of tumors. PMID- 4146424 TI - Diagnostic methods for cerebral tumors. Present situation. PMID- 4146425 TI - Diagnosis of spinal cord tumors. Present situation. PMID- 4146426 TI - The combination of radiation and surgery in oropharynx and laryngopharynx squamous cell carcinomas. PMID- 4146427 TI - Plastic reconstruction after a disfiguring operation of the face and neck. PMID- 4146428 TI - The environmental biology of cancer of the stomach and large intestine. PMID- 4146429 TI - The treatment of malignant tumors of the salivary glands at the Gustave-Roussy institute. PMID- 4146430 TI - Treatment of cancer of the thyroid gland. PMID- 4146431 TI - Surgical treatment of myasthenia. PMID- 4146433 TI - The surgical treatment of primary bronchopulmonary cancer. PMID- 4146432 TI - Thymomas, tumors of the thymic site, and the para-neoplastic immunological syndromes associated with them. PMID- 4146434 TI - Endothoracic neurogenic tumors in children and adults and their endocrine activity. PMID- 4146435 TI - Pulmonary coin lesions and metastases. PMID- 4146436 TI - Morphological precursors of cancer in experimental and human pathology and their clinical significance. PMID- 4146437 TI - Primary cancers of the gastric stump after resection of the stomach in the treatment of ulcers. 3 cures lasting more than 7 years. PMID- 4146438 TI - Metabolically active tumors of the pancreas and the duodenum. PMID- 4146439 TI - The treatment of gastro-intestinal polyps. PMID- 4146440 TI - Chronic ulcero-hemorrhagic rectocolitis and cancer of the large intestine. Prophylactic panproctocolectomy. PMID- 4146441 TI - The results of radical surgery for cancer of the extremities. PMID- 4146442 TI - Modern treatment of bone sarcomas, indications and results. PMID- 4146443 TI - Treatment of pathological fractures. PMID- 4146444 TI - Balance-sheet of breast cancer endocrine surgery. PMID- 4146445 TI - Critical evaluation of methods of destroying the pituitary gland in the treatment of cancer. PMID- 4146446 TI - Radioactive isotopes in the treatment of cancer. PMID- 4146447 TI - Regional perfusion for cancer of the extremities. PMID- 4146448 TI - Modern approaches to experimental cancer research. Roles of viruses and of cigarette smoke in carcinogenesis. PMID- 4146449 TI - The treatment of hepatic metastases by long-term chemotherapeutic infusions. PMID- 4146450 TI - Properties of halophil nicotinamide-adenine dinucleotide phosphate-specific isocitrate dehydrogenase. True Michaelis constants, reaction mechanisms and molecular weights. AB - True values of Michaelis constants of the NADP(+)-specific isocitrate dehydrogenase from Halobacterium salinarium were not very different from those of the apparent constants reported by Aitken et al. (1970). The true constants were affected by salt in a similar manner to that of the apparent constants obtained with NADP(+) at fixed concentrations of 1.0-0.2mm and threo-d(s)-(+)-isocitrate at fixed concentrations of 2.0-0.125mm. The response of apparent V(max.) to salt concentration was highly dependent on fixed substrate concentration in solutions of sodium chloride but much less so in solutions of potassium chloride. At several levels the results emphasize the difficulty of generalizing about the salt relations of a halophil enzyme without adequate attention to substrate concentration. The enzyme has at least two different reaction mechanisms depending on salt concentration. In its ;physiological' form (i.e. in 1.0m potassium chloride), and also in 1.0m-sodium chloride, the reaction mechanism is ordered with NADP(+) the first substrate added and NADPH the last product released. In 0.25m-sodium chloride, however, the mechanism is different and is probably non-sequential. In 4.0m-sodium chloride with low concentrations of either fixed substrate, there was evidence of a co-operative action of the variable substrate. The evidence suggests that salt participates in the reaction mechanism in two ways: one is the reversible addition to the enzyme in a manner analogous to that of a substrate; the other is dead-end complex-formation. The relative contributions of these two types of reaction determine whether salt activates or inhibits the enzyme. In addition, the inhibition caused by high concentrations of sodium chloride is more complex than the corresponding inhibition by potassium chloride. Gel-filtration experiments indicated that at very low salt concentrations the enzyme has an apparent molecular weight of about 70800. In ;physiological' concentrations of potassium chloride the enzyme appears to be a dimer (mol.wt. 122000-135000) and, in 1.0-4.0m-sodium chloride, it behaves as a trimer or tetramer (mol.wt. 224000-251000). A preliminary method of purifying the enzyme is described. PMID- 4146452 TI - The characterization of two reduced nicotinamide-adenine dinucleotide phosphate linked aldehyde reductases from pig brain. AB - 1. NADPH-linked aldehyde reductase from pig, ox and rat brain exhibits non-linear reciprocal plots when partially purified enzyme preparations are studied. 2. In pig brain this non-linearity is due to the presence of two distinct aldehyde reductases, which can be separated by DEAE-cellulose chromatography. 3. These two enzymes can be distinguished by several criteria, including pH optima, Michaelis constants for substrates and their inhibitor sensitivity. 4. The probable role of these enzymes in the metabolism of the aldehydes derived from the biogenic amines is discussed. PMID- 4146451 TI - Metabolism of glutamine and glutamic acid by isolated perfused kidneys of normal and acidotic rats. AB - 1. When isolated kidneys from fed rats were perfused with glutamine the rate of ammonia release at pH7.4 (110-360mumol/h per g dry wt.) was one to two times that of glutamine removal. Glucose formation from 5mm-glutamine was 16mumol/h per g. If kidneys were perfused with glutamine at pH7.1 (10-13mm-sodium bicarbonate) there was no increase in glutamine removal or in the formation of ammonia or glucose. 2. When isolated kidneys from fed rats were perfused with glutamate at pH7.4, glucose formation was 59mumol/h per g, glutamine formation was 182mumol/h per g and ammonia release was negligible. At pH7.1 glutamine synthesis was inhibited and formation of ammonia and glucose were increased. 3. In perfused kidneys from acidotic rats, which had received 1.5% (w/v) NH(4)Cl to drink for 7 10 days, gluconeogenesis from glutamine was enhanced (101mumol/h per g). Glutamine removal and ammonia formation were also increased, compared with the rates in perfused kidney from normal rats. The extra glutamine consumed was equivalent to the extra glucose formed. 4. When the kidney from the 7-10-day acidotic rat was perfused with glutamate gluconeogenesis was increased (113mumol/h per g). Synthesis of glutamine was decreased, and ammonia release was approximately equal to the rate of glutamate removal. 5. The time-course of these metabolic alterations was investigated after the rapid induction of acidosis by infusion of 0.25m-HCl into the right side of the heart. The increase in gluconeogenesis from glutamine developed gradually over several hours. When kidneys from 6h-acidotic rats were perfused with glutamate, formation of glucose and glutamine were both rapid. 6. In acidotic rat kidneys perfused with glutamine, tissue concentrations of glutamate and glucose 6-phosphate were increased compared with those in control perfused kidneys from non-acidotic rats. 7. The results are discussed in terms of control of the renal metabolism of glutamine. In particular, it is suggested that in acidotic rats glucose formation is the major fate of the carbon of the extra glutamine utilized by the kidney, and that inhibition of glutamine synthetase could contribute to the increase in intracellular ammonia concentration in the kidney. PMID- 4146453 TI - The effect of L-ascorbate on catecholamine biosynthesis. AB - l-Ascorbate stimulates the enzymic hydroxylation of phenylalanine in vitro by recycling tetrahydrobiopterin, which reduces O(2) utilized in the reaction. It is suggested that ascorbate might have a similar function in vivo; this would explain the apparent regulation of tyrosine hydroxylase and tryptophan hydroxylase activities by this vitamin. PMID- 4146454 TI - Stereoconfiguration of amino acids in peptides from a mycobacillin-synthesizing cell-free system. AB - The stereoconfiguration of amino acids, as determined by treatment with L-amino acid oxidase, d-amino acid oxidase and l-glutamate decarboxylase (containing l aspartate decarboxylase activity), in the peptides from a mycobacillin synthesizing cell-free system is identical with that of the growing mycobacillin peptide chaid if its synthesis starts from l-proline and is interrupted at various points by amino acid deprivation. PMID- 4146456 TI - Polyarteritis nodosa of the gallbladder, presenting as acute cholecystitis. PMID- 4146455 TI - Glutamate, GABA and the direct cortical response in the rat. PMID- 4146457 TI - Salicylazosulfapyridine in clinical practice. PMID- 4146458 TI - Autoregulatory escape in the gut: a systems analysis. PMID- 4146459 TI - Activation by chemical carcinogens of gamma-glutamyl transpeptidase in rat and mouse liver. PMID- 4146460 TI - Biosynthesis of cholest-5-ene-3beta, 24-diol (cerebrosterol) by bovine cerebral cortical microsomes. PMID- 4146461 TI - Catecholamines in fetal and newborn rat brain. PMID- 4146464 TI - Undescended testes. PMID- 4146463 TI - Muscle transplantation in normal and dystrophic animals. PMID- 4146462 TI - The onic dependence of the strength and spontaneous relations of the potassium contracture induced in the heart of the frog Rana pipiens. AB - 1. The tension generated by isolated frog atrial trabecules, during exposure to solutions containing a high potassium concentration, is not maintained but spontaneously relaxes. The final part of this relaxation can be fitted by a single exponential function.2. The recovery of the tension generating mechanisms following the spontaneous relaxation of a potassium contracture depends on the preceding membrane potential and the time since the last contracture.3. The rate of the exponential phase of the spontaneous relaxation is independent of the [K](o) and hence the membrane potential, the [Ca](o); and when the [Ca](o)/[Na](o) (2) ratio is maintained it is also independent of the [Na](o). This relaxation is not influenced by atropine or pronethalol.4. When sodium is totally excluded from the bathing medium the rate of relaxation of a later potassium contracture is much increased. It is argued that this change is due to a fall in the intracellular sodium concentration.5. The consequences of these results are discussed, and the hypothesis that is favoured would require that contraction is induced by a transient release of calcium into the sarcoplasm, probably triggered by a potential dependent, and probably also transient, influx of calcium through the cell membrane. Relaxation is supposed to occur when this activator-calcium is then removed by an intracellular relaxing system that resembles the sarcoplasmic reticulum of other muscles. What this intracellular structure might be, is also discussed. PMID- 4146465 TI - Pilot studies on the clinical use of the short-lived isotope fluorine-18. PMID- 4146466 TI - Respiratory effects of acebutolol hydrochloride. PMID- 4146467 TI - Regional enteritis and growth retardation without intestinal symptoms. PMID- 4146468 TI - [Isolation of viruses belonging to the California-encephalitis grou group from mosquitoes in Northern Bavaria]. PMID- 4146469 TI - [Hyaluronate lyase from Streptococcus pyogenes. II. Characterization of the hyaluronate lyase]. PMID- 4146470 TI - [Occurrence of neuraminidase and acylneuraminate pyruvate-lyase in Streptococcus sanguis]. PMID- 4146471 TI - [Detection of type-specific streptococcal M-antibodies in the indirect bactericidal test by use of monkey blood]. PMID- 4146472 TI - Study of pathogenesis of enteric Escherichia coli infection in model experiments on rabbits. PMID- 4146473 TI - [Comparative virulence tests in chickens with transparent and opaque colonies of strains of avian mycobacteria of different serotypes]. PMID- 4146474 TI - [Urethral myiasis caused by Muscina stabulans (Fallen)]. PMID- 4146475 TI - [Growth inhibition zones between polymyxin and sulphonamides]. PMID- 4146476 TI - [Experiments on effects of electromagnetic waves on the reactivity of cells and tissues. I. Behavior of leukocytes in an environment irradiated with infrared rays]. PMID- 4146477 TI - [Experiments on the effect of electro-magnetic waves on the reactivity of cells and tissues. II. Effect of an environment irradiated with infrared rays on the readiness of macrophages for phagocytosis]. PMID- 4146478 TI - [Experiments on the effect of electro-magnetic waves on the reactivity of cells and tissues. 3. Effect of irradiation with red-light and microwaves on pinocytosis in FL cell cultures]. PMID- 4146479 TI - [Experiment on the effect of electro-magnetic waves on the reactivity of cells and tissues. IV. Effect of irradiation iwth red-light and microwaves on the reactivity of the chorioallantoic membrane]. PMID- 4146480 TI - [Attempt to explain causes of serious encephalopathy in a small child]. PMID- 4146481 TI - The effect of androgenic hormones on the reduced nicotinamide adenine dinucleotide phosphate:delta-4-3-ketosteroid 5 alpha-oxidoreductase of rat ventral prostate. PMID- 4146482 TI - Adrenal corticosteroid effects upon rat brain mitochondrial metabolism. PMID- 4146484 TI - [Torsion of ectopic testis]. PMID- 4146483 TI - Stimulation by insulin and glucagon of ornithine decarboxylase activity in perfused rat livers. PMID- 4146485 TI - The place of some newer non-anaesthetic drugs in anaesthetic practice. PMID- 4146486 TI - Renal ammoniagenesis and tissue glutamine, glutamine synthetase, and glutaminase I levels in potassium-deficient rats. PMID- 4146487 TI - [Determination of enzyme activity of the pericardial fluid]. PMID- 4146488 TI - Avoidance conditioning in different strains of rats: neurochemical correlates. PMID- 4146489 TI - [Nicotinamide coenzyme level in subcellular fractions of the liver and in the blood of rats following the administration of beta-mercaptoethylamine]. PMID- 4146490 TI - [Reactive changes in the rat adrenals following roentgen irradiation]. PMID- 4146491 TI - [Dental health survey of the population of Pojejena village in the Caras-Severin District]. PMID- 4146492 TI - [Analysis of group-formation processes in perception using choice reaction experiments]. PMID- 4146493 TI - [Postgraduate training of deputies for the chief physicians in work capacity expertise]. PMID- 4146494 TI - [Intratypic differentiation of poliovirus strains, with special reference to vaccination reactions following oral administration]. PMID- 4146495 TI - Pigment production of Staphylococcus aureus PS 80 and its mutants. PMID- 4146496 TI - [Hyaluronate lyase from Streptococcus pyogenes. I. The production and isolation of hyaluronate lyase]. PMID- 4146497 TI - Enterocine-typing of group D streptococci. PMID- 4146498 TI - [Comparative study of 10 selective media for detection of Pseudomonas aeruginosa]. PMID- 4146499 TI - [Defective phages in Chromobacterium]. PMID- 4146500 TI - [Norcardia pigments. Chromatographic properties of the pigments and their significance for differentiation of pigmented Nocardia strains]. PMID- 4146501 TI - The temperature requirements of growth of some mycoplasmas. PMID- 4146502 TI - Observations on experimental sporotrichosis of the muscle. PMID- 4146503 TI - [Significance of Toxoplasma oocysts in the spreading of infection among domestic cats kept for experimental purposes]. PMID- 4146504 TI - [Occurrence of trichinosis in Eastern Slovakia]. PMID- 4146505 TI - [Residual disinfection effect test of O-phenyl-phenol on standard porosity surfaces in certain microclimatic conditions]. PMID- 4146506 TI - [A simple, practical and effective method for the isolation of Salmonellae from surface waters]. PMID- 4146507 TI - [Mechanisms of non-specific resistance to infection. I. Influence of Polidin on the concentration of plasma kinins and on the evolution of experimental infection]. PMID- 4146512 TI - Transmission of hepatitis B antigen. PMID- 4146508 TI - The distribution between gamma-glutamylhydrozamate synthetase and L-glutamine hydroxylamine glutamyltransferase activities in rat tissues. Studies in vitro. AB - Two common ways of measuring the potential for glutamine synthesis in a tissue are the rates of formation of gamma-glutamylhydroxamate either by synthesis from glutamate (the glutamylhydroxamate synthetase reaction) or by transfer from glutamine (the glutamyltransferase reaction); it has not been established, however, that either reaction is a specific measure of glutamine synthetase. By differential extraction of glutamylhydroxamate synthetase and glutamyltransferase activities from water homogenates of several rat tissues I obtained an extract, rich in glutamylhydroxamate synthetase activity but nearly devoid of glutamyltransferase activity, and a fraction, solubilized by deoxycholate from the pellet, which contained virtually no glutamylhydroxamate synthetase activity but most of the original glutamyltransferase activity. Synthesis of glutamine, quantitatively similar to the gamma-glutamylhydroxamate formed by glutamylhydroxamate synthetase, is catalysed in the water extract but not in the particulate fraction. gamma-Glutamylhydroxamate formation by glutamylhydroxamate synthetase and glutamyltransferase shows discrepant substrate and metal specificities and can be differentially inhibited by l-methionine sulphoximine, phosphate and adenine nucleotides. The concordance between the formation of glutamine and gamma-glutamylhydroxamate by glutamylhydroxamate synthetase but not by glutamyltransferase and the different solubilities of the glutamylhydroxamate synthetase and glutamyltransferase enzyme activities demonstrate that these two activities are not inextricably associated; they therefore cannot be catalysed exclusively by the same protein. PMID- 4146510 TI - [Use of oxygen for decreasing human fatigue in flying]. PMID- 4146509 TI - The distinction between gamma-glutamylhydroxamate synthetase and L-glutamine hydroxylamine glutamyltransferase activities in rat tissues. AB - The formation of gamma-glutamylhydroxamate by homogenates under optimum assay condition showed an inconstancy in the ratios of the enzyme activities utilizing l-glutamate and ATP (gamma-glutamylhydroxamate synthetase) and l-glutamine and ADP (l-glutamine-hydroxylamine glutamyltransferase) in a number of normal and neoplastic rat tissues. Although gamma-glutamylhydroxamate synthetase activities in adult livers and kidneys were identical in males and females, l-glutamine hydroxylamine glutamyltransferase activities in the organs of females were significantly lower. The developmental formations of the two activities in liver, kidney, brain and muscle were not simultaneous. The l-glutamine-hydroxylamine glutamyltransferase activity in foetal liver or neonatal kidney could be prematurely evoked by thyroxine, but the gamma-glutamylhydroxamate synthetase activity remained unchanged. Injections of cortisol also had dissimilar effects on the two activities in thymus and hepatomas. The discrepant tissue distribution, asynchronous developmental formation and differential response to several hormonal stimuli provide evidence in vivo that the two activities are not catalysed by the same protein. PMID- 4146513 TI - Hepatitis in the aged. PMID- 4146514 TI - Inhibition by nicotinic acid of hepatic steatosis and alcohol dehydrogenase in ethanol-treated rats. PMID- 4146515 TI - [Concentration of histamine in the blood of children undergoing surgical treatment of chronic suppurative diseases of the lungs]. PMID- 4146516 TI - Studies on peroxisomes. IV. Intracellular localization of NADH2-glyoxylate reductase in rat liver. PMID- 4146517 TI - Effect of ethanol on D-amino acid oxidase. PMID- 4146518 TI - Structure and function of D-amino acid oxidase. V. Effect of urea on the structure of the free enzyme and its benzoate complex. PMID- 4146519 TI - Structure and function of D-amino acid oxidase. VI. Relation between the quaternary structure and the catalytic activity. PMID- 4146520 TI - Effect of chronically administered L-dopa on dopa 5HTP decarboxylase and tyrosine and tryptophan hydroxylases in cat brain. PMID- 4146521 TI - [Effect of specific amino acids on the hot-bath-test in multiple sclerosis patients]. PMID- 4146522 TI - Kinetics of interconversion of sulphamethoxydiazine crystal forms. PMID- 4146523 TI - Effects of solubilization on drug diffusion. PMID- 4146524 TI - A two phase series model for the transport of steroids across the fully hydrated stratum corneum. PMID- 4146525 TI - The interaction of some oral contraceptive steroids with lipid monolayers and with Erythrocytes. PMID- 4146527 TI - Antihistamine-monoamine oxidase inhibitor interaction in rabbits. PMID- 4146526 TI - Homologues of benzilylcholine mustard. PMID- 4146528 TI - The effect of chlorthalidone on blood sugar and glucose tolerance in the rat. PMID- 4146529 TI - Inotropic effects of atropine on ureteral muscle. PMID- 4146530 TI - Investigations of the biosynthesis of novobiocin. PMID- 4146531 TI - Linearization of dissolution rate curves by the Weibull distribution. PMID- 4146532 TI - Urea increases serum albumin binding of drugs. PMID- 4146533 TI - The effect of some oral contraceptive steroids on platelet electrophoretic mobility in vitro. PMID- 4146534 TI - The antipyretic effect of alpha-methyldopa in experimental fever. PMID- 4146535 TI - Absorption of iodipamide from the biliary system of the rabbit. PMID- 4146536 TI - Possible role of gamma-aminobutyric acid in paraoxon-induced convulsions. PMID- 4146537 TI - Monoamine metabolites in aqueous humour. PMID- 4146538 TI - Interaction between sodium metabisulphite and PMN. PMID- 4146539 TI - Decreased conversion of tyrosine to catecholamines in the brain of rats treated with p-chlorophenylalanine. PMID- 4146540 TI - Comparative convulsant activity of various penicillins after intracerebral injection in mice. PMID- 4146541 TI - The action of vasoactive drugs on longitudinal and circular muscle of dog mesenteric vein. PMID- 4146542 TI - Metabolism and excretion of diethylpropion in man under acidic urine conditions. PMID- 4146543 TI - Competitive binding of two drugs for a single binding site on albumin: a circular dichroic study. PMID- 4146544 TI - Continuous shear, viscoelastic and spreading properties of a new topical vehicle, FAPG base. PMID- 4146545 TI - Adsorption of benzoic acid on sulphadimidine: suppressive effect of some hydrophilic polymers. PMID- 4146546 TI - Mass spectrometry in the analysis of steroid drugs and their metabolites: electron-impact-induced fragmentation of ring D. PMID- 4146547 TI - The extraction and estimation of the cannabinoids in Cannabis sativa L. and its products. PMID- 4146548 TI - Steryl esters of Digitalis purpurea L. herb. PMID- 4146549 TI - Catecholamine concentrations in discrete areas of the rat brain after the pre- and neonatal administration of phencyclidine and imipramine. PMID- 4146550 TI - Some observations on the pulmonary artery of the guinea-pig. PMID- 4146551 TI - On the "quinidine-like action" of some antiarrhythmic agents. PMID- 4146552 TI - Selective inhibition of angiotension-induced contractions of smooth muscle by indomethacin. PMID- 4146553 TI - On the interaction between pimozide and alpha-methyltyrosine. PMID- 4146554 TI - Blocking effect of alpha-methyltyrosine on amphetamine based reinforcement. PMID- 4146555 TI - Penetration of 5-hydroxyindoleacetic acid across the blood-cerebrospinal fluid barrier. PMID- 4146556 TI - Fluorometric determination of 3-methoxytyramine and 3-methoxy-4 hydroxyphenylethanol. PMID- 4146557 TI - Determination of tolbutamide and chlorpropamide in biological fluids. PMID- 4146558 TI - Chlorpromazine "hydroxylamines" in red blood cells as major metabolites of chlorpromazine in man. PMID- 4146559 TI - N-ethyl-alpha-methyl-alpha-(m-trifluoromethylbenzyl)nitrone--the major in vitro metabolic product of fenfluramine in guinea-pig liver microsomal fractions. PMID- 4146560 TI - The central action of antihypertensive drugs, mediated via central alpha receptors. PMID- 4146562 TI - Enhancement of serum renin activity by exercise in the rat. PMID- 4146561 TI - Effects of adrenalectomy and of hypophysectomy on the development of sound withdrawal hypertension. PMID- 4146563 TI - Some typical recent cases in negligence. PMID- 4146565 TI - The role of the general practitioner in society: a radio talk given by Professor M.A. De Kock, Chairman of the Organizing Committee of the 49th Medical Congress to be held in Cape Town on 23-27 July 1973. PMID- 4146564 TI - Effectiveness of sectral (M & B 17803A) as a beta-blocking agent in man. PMID- 4146566 TI - Purification of sea nettle nematocyst toxins by gel diffusion. PMID- 4146567 TI - Interaction of the hemolysin of Chironex fleckeri tentacle extracts with lipid monolayers. PMID- 4146568 TI - The intensity of anxiety in relation to the formation and amelioration of psychiatric symptoms. PMID- 4146569 TI - [Beta-blocking agents in anesthesia and resuscitation]. PMID- 4146570 TI - Cost-benefit analysis of a hospital and university based prevocational program. PMID- 4146571 TI - [Host reactions provoked by implants, stored in 10 formaldehyde, in the mandibles of albino rats]. PMID- 4146572 TI - The effect of prolonged treatment with oxyfedrine on intracellular potentials and on other features of cardiac function in rabbits and guinea-pigs. AB - 1. Previous work in acute experiments has shown that the main pharmacological action of oxyfedrine is stimulation of beta-adrenoceptors, yet there have been clinical reports that the drug is beneficial in the treatment of angina pectoris.2. In the present experiments rabbits and guinea-pigs were treated for several weeks with daily i.p. injections of oxyfedrine.3. A daily dosage of 15 mg/kg oxyfedrine had no effect on growth rate for 4 weeks, but thereafter the growth rate of treated animals fell below that of controls.4. The heart weights of the treated animals, expressed as a percentage of body weight, were significantly lower than those of controls.5. Measurement of intracellular potentials in hearts taken from treated rabbits showed that the main effects were a reduction in the maximum rate of depolarization and a prolongation of the plateau of the action potential.6. Guinea-pigs treated for 6 weeks with 15 mg/kg oxyfedrine daily i.p. were protected to some extent from the toxic effect of ouabain infused intravenously. PMID- 4146573 TI - A comparison of the effects of chemical sympathectomy by 6-hydroxydopamine in newborn and adult rats. AB - 1. The effects of chemical sympathectomy with 6-hydroxydopamine (6-OHDA) on the cardiovascular system of the rat were compared in, (a) 10-week-old rats treated during the first 14 days after birth with 150 mug/g subcutaneously, and (b) adult rats injected intravenously with 2 x 50 mg/kg on day 1 and 2 x 100 mg/kg on day 7 and the experiments performed on day 8.2. Intravenous administration of 6-OHDA to adult rats almost completely abolished the pressor responses to stimulation of the entire sympathetic outflow in the pithed rat, the contractions of the lower eyelid to stimulation of the cervical sympathetic trunk and the vasconstrictor responses produced by periarterial nerve stimulation of the isolated renal artery preparation. Pressor responses to physostigmine and to tyramine were markedly reduced or abolished in anaesthetized and pithed rat preparations, respectively.3. In corresponding experiments, 10-week-old rats treated as newborns with 6-OHDA showed a marked reduction in the stimulation-induced pressor responses and contractions of the lower eyelid, but completely normal vasoconstrictor responses to periarterial nerve stimulation of the isolated perfused renal artery were obtained. The pressor responses to physostigmine were slightly reduced but the tyramine responses were unchanged.4. Treatment with 6 OHDA at birth caused an almost complete and long-lasting noradrenaline depletion in the heart, spleen, salivary glands and ileum but only a partial depletion in the mesentery from 10-week-old rats. These low noradrenaline levels showed no recovery in rats up to an age of 4 months. The tyrosine hydroxylase activity in both the cervical and stellate ganglia from 10-week-old rats was markedly reduced by treatment with 6-OHDA after birth.5. Injections of 6-OHDA after birth produce an almost complete and permanent sympathectomy of various adrenergically innervated organs in the rat. The vascular system represents a major exception, exhibiting a surprisingly high resistance to this type of chemical adrenergic denervation. PMID- 4146575 TI - Inhibition by gamma-hydroxybutyrate of chlorpromazine-induced increase in homovanillic acid. AB - 1. gamma-Hydroxybutyrate and its lactone precursor, gamma-butyrolactone, when administered in anaesthetic doses block the increase in the cerebral concentration of homovanillic acid normally observed after administration of chlorpromazine or haloperidol.2. Other hypnotics such as glutethimide, urethane, chloralose, chloral hydrate and thiopentone do not have this ability even when administered in anaesthetic doses.3. The ability of gamma-hydroxybutyrate to block the neuroleptic-induced increase in cerebral homovanillic acid is not due to a reduction in body temperature since a similar effect is observed in rats treated under conditions (32 degrees C) in which body temperature remains normal.4. Possible mechanisms for this action of gamma-hydroxybutyrate are discussed. PMID- 4146574 TI - Selective blockade of beta-adrenoceptors by 1-(p-allylphenoxy)-3-isopropylamino-2 propanol hydrochloride (h 64-52) in the anaesthetized dog. AB - 1. The beta-adrenoceptor blocking properties of 1-(p-allylphenoxy)-3 isopropylamino-2-propanol hydrochloride (H 64/52) on the cardiovascular and bronchomotor responses to isoprenaline have been determined in the anaesthetized dog.2. H 64/52 selectively blocked the isoprenaline-induced increase in heart rate, contractile force and reduction in airway pressure in the same dose range.3. H 64/52 produced a minimal blockade of vascular beta-adrenoceptors which was apparent only when the isoprenaline-induced fall in diastolic pressure was considered. No significant vascular beta-adrenoceptor blockade with H 64/52 could be shown with the femoral arterial flow or hind-limb perfusion studies.4. These results further support the hypothesis that several different beta-adrenoceptor subtypes exist in the dog. The beta-adrenoceptors subserving cardiac stimulation and bronchodilation appear to be similar and both differ from the beta adrenoceptor subserving vasodilatation. PMID- 4146576 TI - Venomous animal injuries. PMID- 4146577 TI - Caries experience of 11-17-year-old children. A mixed longitudinal epidemiological study. PMID- 4146578 TI - In vitro studies in Tubularia: a morphological role for digestive cells. PMID- 4146579 TI - Drug-induced changes of striatal cholinergic and dopaminergic functions in rats with spreading depression. PMID- 4146580 TI - Effect of ethanol on the hydroxylation of tyrosine and tryptophan in rat brain in vivo. PMID- 4146581 TI - Some actions of 4,17a-dimethyl-4,17a-diaza-D-homo-5alpha-androstane dimethiodide (HS-342), a new neuromuscular blocking drug. PMID- 4146582 TI - Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. PMID- 4146583 TI - Plasma protein binding of 7-hydroxy- 1-tetrahydrocannabinol: an active 1 tetrahydrocannabinol metabolite. PMID- 4146585 TI - Micromethod for the determination of bupivacaine in maternal and foetal blood during obstetric analgesia. PMID- 4146584 TI - Plasma half-lives, plasma metabolites and anticoagulant efficacies of the enantiomers of warfarin in man. PMID- 4146586 TI - Kinetics of hydrolysis of polyoxyethylene (20) sorbitan fatty acid ester surfactants. PMID- 4146587 TI - Release of dipicolinic acid and calcium and activation of Bacillus stearothermophilus spores as a function of time, temperature and pH. PMID- 4146588 TI - Preliminary observations on the uptake of catecholamines in synaptosomes of opiate-treated animals. PMID- 4146589 TI - Two cannabidiol metabolites formed by rat liver. PMID- 4146590 TI - The uptake and metabolic fate of cannabinoids in rat brains. PMID- 4146591 TI - Antagonistic actions of alpha-methylnoradrenaline derived from alpha-methyldopa. PMID- 4146592 TI - Biphasic action of a 5-hydroxytryptamine inhibitor on fenfluramine-induced anorexia. PMID- 4146593 TI - Cardiovascular effects of 5-hydroxytryptophan in anaesthetized dogs. PMID- 4146594 TI - Potentiation of leptazol seizures by 6-hydroxydopamine. PMID- 4146595 TI - Effects of dihydroergotamine on glucose and galactose tolerance in the rabbit. PMID- 4146596 TI - On the use of ethanol as a scavenger in storing labelled dopa and 5 hydroxytryptamine in aqueous solutions. PMID- 4146597 TI - Effects of desipramine and reserpine on 'free' and 'bound' acetylcholine in rat brain. PMID- 4146599 TI - The preferred conformation of cyclophosphamide. PMID- 4146598 TI - Antibacterial activity of phenylmercuric nitrate in zinc sulphate and adrenaline eye drops B.P.C. 1968. PMID- 4146600 TI - Investigations into the biosynthesis of novobiocin. PMID- 4146601 TI - Nutrition and the body's defense mechanism. PMID- 4146602 TI - Malonyl-CoA and fatty acid synthesis. PMID- 4146603 TI - Marijuana induced state-dependent verbal learning. PMID- 4146604 TI - [A dropper needle and a stylet for mosquito dissection]. PMID- 4146605 TI - [Idiopathic hypertrophic subvalvular stenosis: surgical treatment. Review of 10 cases]. PMID- 4146606 TI - [Allergic, vascular purpura due to urea derivatives with bromine content]. PMID- 4146607 TI - Current concepts of hemostasis. Progress report on platelet aggregation. PMID- 4146608 TI - [Effect of majeptil on certain somato-autonomic functions in patients with schizophrenia]. PMID- 4146609 TI - [First aid for patients with pulmonary edema]. PMID- 4146610 TI - [Clinico-morphological characteristics of pulmonary lesions in periarteritis nodosa]. PMID- 4146611 TI - [Morphological characteristics of the rejection reaction of the transplanted kidney in experimental autoimmune glomerulonephritis]. PMID- 4146612 TI - Mesenteric circulation in cardiogenic shock with and without alpha-receptor blockade. PMID- 4146613 TI - Reflex beta-adrenergic vasodilatation in the cat. PMID- 4146614 TI - Effects and mechanisms of action of dopamine on regional hemodynamics in the conscious dog. PMID- 4146615 TI - Presidential address: "Future shock and the surgeon". PMID- 4146616 TI - A longitudinal clinical study of oral cleanliness and dental caries in school children. PMID- 4146617 TI - Inhibition of mitochondrial electron-transport systems by nor-isoguaiacin. PMID- 4146618 TI - Feeding and aggressive behavior evoked by hypothalamic stimulation in a cichlid fish. PMID- 4146619 TI - Contrasting twitch and latency relaxation in skeletal muscle. PMID- 4146620 TI - Oxygen affinity of avian hemoglobins. PMID- 4146621 TI - Erythrocyte sodium and potassium levels in normal and anemic mice. PMID- 4146622 TI - Renal adaptations to macro- and microhabitats in the family Cricetidae. PMID- 4146623 TI - The circannual variations of thyroid activity in the woodchuck (Marmota monax). PMID- 4146624 TI - The balance of cations in the plasma of vertebrates and its significance in relation to the properties of cell membranes. PMID- 4146625 TI - The suitability of Melanoplus differentialis for electrophysiological investigation based on hemolymph ionic and anatomical studies. PMID- 4146626 TI - Effects of fasting on the blood chemistry of the rattlesnake, Crotalus atrox. PMID- 4146627 TI - Reversal of gamma-aminobutyric acid inhibition by carbon dioxide. PMID- 4146628 TI - Protein synthesis in Fundulus heteroclitus muscle. PMID- 4146629 TI - The relationship between cell sizes, respiration rates and survival of amphibian tissues in long-term organ cultures. PMID- 4146630 TI - Thermal patterns in the heating and cooling of Iguana iguana and Ctenosaura hemilopha. PMID- 4146631 TI - Histone fractions in chicken bursa of fabricius and thymus. PMID- 4146632 TI - Depression of gustatory sweet response by alloxan. PMID- 4146633 TI - Effects of thermal acclimation on physiological responses to handling stress, cortisol and aldosterone injections in the goldfish, Carassius auratus. PMID- 4146634 TI - Metabolite changes in the neonate fowl in response to cold stress. PMID- 4146635 TI - Intestinal pseudo-obstruction. PMID- 4146636 TI - Spectral properties of glutamate dehydrogenase. Complexes involving substrate analogues. PMID- 4146637 TI - [Drug therapy of aphasic disorders following brain injury and cerebral vascular involvement]. PMID- 4146638 TI - Genotype-environmental interactions in Schizophyllum commune. 3. The relationship between mean expression and sensitivity to change in environment. PMID- 4146639 TI - Rat adrenal 5alpha-reductase activity and the effect of oestradiol, testosterone propionate and adrenocorticotrophin in intact and gonadectomized rats. PMID- 4146640 TI - The adrenals and gonads of congenitally thymusless nude mice. PMID- 4146641 TI - Further studies on the mechanism of antipsychotic action: potentiation by alpha methyltyrosine of thioridazine effects in chronic schizophrenics. PMID- 4146642 TI - In-vivo measurements of tryptophan and tyrosine hydroxylase activities in mouse brain. PMID- 4146643 TI - Torsion of the previously operated testicle. PMID- 4146644 TI - Management of inguinal lymph nodes in patients with testicular tumors following orchiopexy, inguinal or scrotal operations. PMID- 4146645 TI - [Hemodynamic changes in patients with chronic pneumonia and cor pulmonale under the influence of prednisolone and benzohexonium inhalation]. PMID- 4146646 TI - Pharmacological studies of the therapy of shock. PMID- 4146648 TI - Methaqualone, methyprylon, and glutethimide clearance by the ACAC microcapsule artificial kidney: in vitro and in patients with acute intoxication. PMID- 4146647 TI - Structure-function relationships in lactate dehydrogenase. AB - The binding of coenzyme and substrate are considered in relation to the known primary and tertiary structure of lactate dehydrogenase (EC 1.1.1.27). The adenine binds in a hydrophobic crevice, and the two coenzyme phosphates are oriented by interactions with the protein. The positively charged guanidinium group of arginine 101 then folds over the negatively charged phosphates, collapsing the loop region over the active center and positioning the unreactive B side of the nicotinamide in a hydrophobic protein environment. Collapse of the loop also introduces various charged groups into the vicinity of the substrate binding site. The substrate is situated between histidine 195 and the C4 position on the nicotinamide ring, and is partially oriented by interactions between its carboxyl group and arginine 171. The spatial arrangements of these groups may provide the specificity for the L-isomer of lactate. PMID- 4146649 TI - The pathways of nitrogen fixation. PMID- 4146650 TI - Factitious hypoglycemia. PMID- 4146651 TI - Angina pectoris induced by dumping syndrome in idiopathic hypertrophic subaortic stenosis. PMID- 4146652 TI - [Action of alpha-methyl-p-tyrosine on subesophageal ganglionic catecholamines in Helix pomatia: fluorescence microscopy study]. PMID- 4146653 TI - Haemodynamic and electrocardiographic effects of practolol during upright exercise in coronary heart disease. PMID- 4146654 TI - Determinants of cardiac noradrenaline depletion in human congestive failure. PMID- 4146655 TI - Functional monitoring of spinal cord activity during spinal surgery. PMID- 4146656 TI - Phenobarbital liver microsomal induction in MHV-3 viral hepatitis of the mouse. PMID- 4146657 TI - Effect of adrenergic amines on the membrane potential of guinea-pig liver parenchymal cells in short term tissue culture. PMID- 4146658 TI - Cells involved in the graft-versus-host reaction in vitro. PMID- 4146659 TI - Nitrite reductase-deficient mutants of Escherichia coli K12. PMID- 4146660 TI - Role of mosquitoes in transmission of hepatitis B antigen. PMID- 4146661 TI - Smallpox vaccination following childhood postvaccinal encephalitis. PMID- 4146662 TI - Inhibiting effects of antihistamine and antiserotonin drugs on the bone marrow reaction caused by endotoxin. PMID- 4146663 TI - Pharmacological activity of some neuro-transmitters in the isolated thoracic duct of dogs. PMID- 4146664 TI - Dopa decarboxylase in medullary carcinoma of the thyroid. PMID- 4146665 TI - Pediatric surgery. 3. PMID- 4146666 TI - Surface properties of the hemolytic fraction derived from tentacle extracts of Chironex fleckeri. PMID- 4146667 TI - Preliminary studies of nematocysts from the jellyfish Stomolophus meleagris. PMID- 4146668 TI - Toxicity of the zoanthid Palythoa tuberculosa. PMID- 4146669 TI - Fatal intoxication of rabbits, sheep and monkeys by the venom of the sea wasp (Chironex fleckeri). PMID- 4146670 TI - [NADP synthesis in the regenerating rat liver]. PMID- 4146671 TI - Fatty acid synthesis in the brown fat and liver of foetal and newborn rabbits. AB - The postnatal fall in fatty acid synthesis in the liver and brown fat of newborn rabbits is accompanied in both tissues by a decrease in the capacities of the enzymes of fatty acid synthesis and an apparent increase in the degree of inhibition of one or more of these enzymes. PMID- 4146673 TI - Effects of infection with Diplococcus pneumoniae on synthesis of ribonucleic acids in rat liver. AB - Rats infected with virulent Diplococcus pneumoniae developed a significant increase in the rate of incorporation of labelled orotate into hepatic RNA when compared with pair-fed controls inoculated with heat-killed organisms. The finding was readily detected in rats raised on either a low-protein diet (6% casein) or a diet containing adequate amounts of protein (18% casein). The increase in hepatic RNA synthesis was observed by 12h and was maximal by 16-20h after inoculation with the D. pneumoniae. Most of the infection-related increase in RNA synthesis was associated with the bound ribosomal RNA fraction of the liver. A small but less significant increase was observed in the synthesis of free ribosomal RNA. The increased synthesis of RNA in the liver of infected rats resulted in a marked elevation of the liver RNA/DNA ratio, the major increase being observed in concentration of bound ribosomal RNA fraction. When followed sequentially, the infection-related increase in synthesis of hepatic RNA was preceded by a flux of amino acids into liver and was followed by elevated synthesis rates of serum globulin proteins. These findings suggest that the infectious process was able to regulate hepatic RNA synthesis by altering the rate of transcription of new RNA. This mechanism was stimulated even in rats that had been severely depleted of body protein and amino acids by feeding them on a low-protein diet. The infection-related stimulation of liver RNA and protein synthesis thus appeared to take place at the expense of other body proteins. PMID- 4146672 TI - Studies on the enzymology of purified preparations of brush border from rabbit kidney. AB - 1. A method for the preparation of brush border from rabbit kidneys is described. Contamination by other organelles was checked by electron microscopy and by the assay of marker enzymes and was low. 2. Seven enzymes, all hydrolases, were substantially enriched in the brush-border preparation and are considered to be primarily located in this structure. They are: alkaline phosphatase, maltase, trehalase, aminopeptidase A, aminopeptidase M, gamma-glutamyl transpeptidase and a neutral peptidase assayed by its ability to hydrolyse [(125)I]iodoinsulin B chain. 3. Adenosine triphosphatases were also present in the preparation, but showed lower enrichments. 4. Alkaline phosphatase was the most active phosphatase present in the preparation. The weak hydrolysis of AMP may well have been due to this enzyme rather than a specific 5'-nucleotidase. 5. The two disaccharidases in brush border were distinguished by the relative heat-stability of trehalase compared with that of maltase. 6. The individuality of the four peptidases was established by several means. The neutral peptidase and aminopeptidase M, both of which can attack insulin B chain, differed not only in response to inhibitors and activators but also in the inhibitory effect of a guinea-pig antiserum raised to rabbit aminopeptidase M. This antiserum inhibited both the purified and the brush border activities of aminopeptidase M. The neutral peptidase and gamma-glutamyl transpeptidase were unaffected but aminopeptidase A was weakly inhibited. The characteristic responses to Ca(2+) and serine with borate served to distinguish aminopeptidase A and gamma-glutamyl transpeptidase from other peptidases. 7. No dipeptidases, tripeptidases or carboxypeptidases were identified as brush-border enzymes. 8. Incubation of brush border with papain released almost all the aminopeptidase M activity but only about half the activities of maltase, gamma glutamyl transpeptidase and aminopeptidase A. No release of alkaline phosphatase, trehalase or the neutral peptidase was observed. PMID- 4146674 TI - Hyperproduction mutation in the dihydrofolate reductase gene of Diplococcus pneumoniae: some effects on synthesis correlate with the presence of a modified enzyme form. PMID- 4146675 TI - The effects of practolol on angina pectoris induced by atrial pacing. PMID- 4146676 TI - CNS effects of 1-isopropylamino-3-(4-indanoxy)-2-propanol hydrochloride (USVC 6524). PMID- 4146677 TI - The transfer of salicylic acid across a cellophane membrane from micellar solutions of polysorbates 20 and 80. PMID- 4146678 TI - A note on the solubilization of preservative mixtures by cetomacrogol. PMID- 4146679 TI - The interaction of penicillins with phospholipids. PMID- 4146680 TI - Use of substituent constants in structure-activity relations and the importance of the choice of standard state. PMID- 4146681 TI - The activity of beta-adrenoceptor blocking agents in protecting mice from the cardiotoxic effects of ouabain. PMID- 4146682 TI - Behavioural and biochemical interaction between caffeine and L-dopa. PMID- 4146683 TI - The excitation of neurons by noradrenaline. PMID- 4146684 TI - Differential effects of amphetamine, fenfluramine and norfenfluramine stereoisomers on the increase of striatum homovanillic acid in rats. PMID- 4146685 TI - The effect of oral administration of various sugars on blood ethanol concentrations in man. PMID- 4146686 TI - Gas chromatographic determination of ethosuximide and phensuximide in plasma and urine of man. PMID- 4146687 TI - The identification, properties and analysis of N-hydroxyamphetamine--a metabolite of amphetamine. PMID- 4146688 TI - Metabolism of amitriptyline, nortriptyline, imipramine and desipramine to yield hydroxylamines. PMID- 4146689 TI - Glutarimide antibiotics and drug metabolism in the rat. PMID- 4146690 TI - Iron deficiency anaemia and drug metabolism. PMID- 4146691 TI - Iminostilbene--a metabolite of carbamazepine isolated from rat urine. PMID- 4146692 TI - Interaction between DDT and lecithin in spread monolayers. PMID- 4146693 TI - Preparation of 9-tetrahydrocannabinol for intravenous injection. PMID- 4146694 TI - An intravenous formulation of 9-tetrahydrocannabinol using a non-ionic surfactant. PMID- 4146695 TI - Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system. PMID- 4146696 TI - The effect of trivastal, haloperidol and dibutyryl cyclic AMP on (14C)dopamine synthesis in rat striatum. PMID- 4146697 TI - Pharmacological studies on a possible role of central noradrenaline neurons in respiratory control. PMID- 4146698 TI - Dissociation of alpha adrenergic receptor protection from inhibition of H phenoxybenlamine binding in vascular tissue. PMID- 4146699 TI - The regulation of pineal serotonin by a beta adrenergic receptor. PMID- 4146700 TI - Comparison of the beta receptor blocking properties of two analogs of dichloroisoproterenol (DCI). PMID- 4146701 TI - The selective beta receptor blocking properties of DL-1-(2-acetyl-4-n butyramidophenoxy)-2-hydroxy-3-isopropylaminopropane HC1 (M & B 17803-A) in the anesthetized dog. PMID- 4146702 TI - Dromotropic effects of optical isomers of beta blockers on the cross-circulated canine-atrioventricular node preparation. PMID- 4146703 TI - Alcohol withdrawal reactions in mice: effects of drugs that modify neurotransmission. PMID- 4146704 TI - Effect of local anesthetics on pharmacologic receptor systems of smooth muscle. PMID- 4146705 TI - [Generalized periarteritis nodosa]. PMID- 4146706 TI - [Effects of a heart specific beta blockader (practolol) following acute experimental coronary occlusion]. PMID- 4146707 TI - [Significance of gamma glutamyltranspeptidase in clinical diagnosis]. PMID- 4146708 TI - [Quantitative determination of the beta receptor blockade in man]. PMID- 4146709 TI - [Modification of the hypoxic metabolism in circulation disordered extremities using drugs]. PMID- 4146710 TI - [Mechanism of hemiglobin formation by salicylazosulfapyridine (azulfidine)]. PMID- 4146711 TI - [Immunosuppressive therapy of collagenoses]. PMID- 4146712 TI - Cytochemical demonstration and localization of adenyl cyclase in skeletal and cardiac muscle. PMID- 4146713 TI - Regulation of cyclic AMP levels in brain tissue. PMID- 4146714 TI - Psychopharmacological agents and the cyclic AMP system of rat brain. PMID- 4146715 TI - [A study of aggregating immunoglobulins in horses ("AI" or IgB or IgI)]. PMID- 4146716 TI - Protection against secondary syndrome by facilitating immune sera. PMID- 4146718 TI - School fluoridation for the prevention of dental caries. PMID- 4146719 TI - Alternatives to fluoridation. PMID- 4146720 TI - A sentence completion test assessing safety and esteem motives. PMID- 4146721 TI - Replicated empirical correlated of the MMPI 8-9-9-8 code type. PMID- 4146722 TI - History of fluoride, dental fluorosis, and concentrations of fluoride in surface layer of enamel of caries-free naval recruits. PMID- 4146717 TI - Cardiac histological and serum-biochemical changes produced by various adrenergic stimulant drugs in the rat. PMID- 4146723 TI - The relationship of frequency of toothbrushing, oral hygiene, gingival health, and caries-experience in school children. PMID- 4146729 TI - Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. PMID- 4146730 TI - Therapeutic implications of the intestinal microflora. PMID- 4146731 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 38-1973. PMID- 4146732 TI - [Bronchodilator effects of terbutaline in injection]. PMID- 4146733 TI - The World Health Organization. 25 years of endeavour. PMID- 4146734 TI - Positive-contrast peritoneography and heriography. PMID- 4146735 TI - [A population study on glutathion reductase activity in human erythrocytes. The effects of nutrition and heredity]. PMID- 4146736 TI - One-electron and two-electron transfer mechanisms in enzymic oxidation-reduction reactions. PMID- 4146737 TI - [Neuroleptoanalgesia]. PMID- 4146738 TI - [Chronic lymphoid leukemia followed by periarteritis nodosa]. PMID- 4146739 TI - [Immunological response of the recipient of a renal allograft]. PMID- 4146740 TI - [Use of droperidol in the treatment of cardiogenic shock]. PMID- 4146741 TI - Attenuation of amphetamine-induced motor stimulation and stereotypy by 6 hydroxydopamine in the rat. AB - 1. In accord with previous reports, intraventricular administration of 6 hydroxydopamine (250 mug) to rats did not influence spontaneous locomotor activity. Neither was the stereotyped behaviour seen after high doses of (+) amphetamine (5 mg/kg) changed by this treatment. Increases in motor activity induced by (+)-amphetamine (0.5 and 1.0 mg/kg) were significantly reduced after 6 hydroxydopamine.2. When 6-hydroxydopamine (250 mug) was administered to tranylcypromine (5 mg/kg) pretreated animals, spontaneous activity was significantly reduced. The stimulant effects of (+)-amphetamine (0.5 and 1.0 mg/kg) were completely abolished and amphetamine stereotypy (5.0 mg/kg) was absent or reduced after this treatment.3. Bilateral injections of 6 hydroxydopamine (10 mug) into the substantia nigra abolished the more pronounced features of amphetamine stereotypy. However, although significantly reduced, amphetamine-induced locomotor stimulation was observed in these animals. Spontaneous activity was also reduced.4. These observations suggest that dopaminergic nigro-striatal neurones mediate some of the stimulant effects of amphetamine as well as being of critical importance in amphetamine-induced stereotypy. However, other catecholaminergic neurones also appear to be involved in amphetamine motor stimulation. The results are consistent with the view that amphetamine exerts its behavioural effects indirectly through its action on brain catecholamines. PMID- 4146742 TI - Effects of drugs and of electrical stimulation on the muscularis mucosae of rabbit large intestine. AB - 1. The muscularis mucosae of the rabbit large intestine shows spontaneous rhythmic contractions with an average frequency of about 11/minute.2. The muscularis mucosae responds to acetylcholine, adrenaline and noradrenaline in a manner similar to that of whole segments of terminal large intestine.3. The muscularis mucosae would seem to have a cholinergic motor innervation. PMID- 4146744 TI - [Cycle of a mosquito-borne rodent filaria]. PMID- 4146743 TI - Effects of oxyfedrine on isolated portal vein and other smooth muscles. AB - 1. Oxyfedrine (0.01-1.0 mug/ml), inhibited spontaneous myogenic activity in rat isolated portal vein and carbachol-induced contractions of rat isolated uterus, and relaxed the rabbit duodenum and the guinea-pig tracheal chain preparation. These actions were prevented by the beta-adrenoceptor blocking drug alprenolol. Oxyfedrine was a relatively weak beta-adrenoceptor stimulant (10-100 times less active than isoprenaline) but its actions were more prolonged.2. In the same concentrations, oxyfedrine reduced or prevented the inhibition of myogenic activity of the rat portal vein induced by isoprenaline and by repeated doses of oxyfedrine itself, acting as a partial agonist at beta-adrenoceptor sites.3. Oxyfedrine, 1-12 mug/ml increased myogenic activity in the rat portal vein. This effect was not due to direct or indirect stimulation of alpha-adrenoceptors (because it was unaffected by phentolamine) or to potentiation of acetylcholine or 5-hydroxytryptamine.4. Oxyfedrine (>20 mug/ml) inhibited spontaneous myogenic activity in the portal vein and relaxed the saphenous vein contracted with noradrenaline. This spasmolytic effect of the drug was not due to beta adrenoceptor stimulation or to inhibition of phosphodiesterase since it was unaffected by alprenolol and by concentrations of imidazole which antagonized the effects of the active phosphodiesterase inhibitor, papaverine. In the portal vein this effect of oxyfedrine was similar to that of the calcium inhibitor iproveratril; some of the effects of oxyfedrine on venous smooth muscle may be mediated through effects on calcium transport. PMID- 4146745 TI - Dermatological side effects with psychotropics. PMID- 4146746 TI - [Drug interferences and incompatibilities of substances affecting the central nervous system. 4. Neuroleptics]. PMID- 4146747 TI - Immunological induction of DNA synthesis in mouse peritoneal macrophages. An expression of cell-mediated-immunity. PMID- 4146748 TI - Changes in guinea-pig liver heparin and histamine during anaphylaxis. PMID- 4146749 TI - Immunochemical studies on function of NADH: hemeprotein oxidoreductase in electron transport system of chromatophores from Rhodospirillum rubrum. PMID- 4146750 TI - Immunological studies on function of NADH: quinone oxidoreductase in electron transport system of chromatophores from Rhodospirillum rubrum. PMID- 4146751 TI - Adenosine 3', 5'-monophosphate and histone phosphorylation during enzyme induction by glucagon in rat liver. PMID- 4146752 TI - A beta-adrenergic receptor of the turkey erythrocyte. I. Binding of catecholamine and relationship to adenylate cyclase activity. PMID- 4146753 TI - Lack of correlation between catecholamine effects on cyclic adenosine 3':5' monophosphate and gluconeogenesis in isolated rat liver cells. PMID- 4146754 TI - Effects of fatigue produced by isokinetic exercise on the communication ability of aphasic adults. PMID- 4146755 TI - [Histoenzymochemical study of the liver of white rats with experimental hypothyrosis]. PMID- 4146756 TI - Enteritis associated with pneumococci. PMID- 4146757 TI - The facial-digital-genital (Aarskog) syndrome. PMID- 4146758 TI - Measurement of personality traits: theory and technique. PMID- 4146759 TI - Measurement of impairment and disability in dermatology. PMID- 4146760 TI - The Pueblo incident. A comparison of factors related to coping with extreme stress. PMID- 4146761 TI - Effects of vinblastine on catecholamine-biosynthetic enzymes in heart, sympathetic ganglion and adrenal glands of rats. AB - 1. The effect of vinblastine on the activities of dopamine-beta-hydroxylase (DBH) in heart, superior cervical ganglion and adrenal glands of rats and tyrosine hydroxylase (TH) and phenylethanolamine-N-methyl transferase (PNMT) in adrenal glands was examined.2. In the superior cervical ganglion and heart, DBH activity decreased within hours, reached a minimum in 3 to 5 days and slowly returned towards normal over the next 2 weeks.3. There was an increase in the activities of TH, DBH and PNMT in adrenal glands which was prevented by adrenal denervation.4. When the same total dose of vinblastine was administered subdivided over a period of 5 days, enzyme activities in heart, superior cervical ganglion or adrenal glands remained unchanged. PMID- 4146762 TI - Characterization of -adrenoceptors in the myocardium. AB - 1. In the driven rabbit left atrium alpha-adrenoceptors mediate the inotropic effect of phenylephrine and the prolongation of functional refractory period by sympathomimetic amines.2. These receptors are highly sensitive to blockade by phentolamine and phenoxybenzamine.3. Prolongation of functional refractory period is greater with the secondary amines, phenylephrine, adrenaline and epinine, than with the primary amines, norphenylephrine, noradrenaline and dopamine. PMID- 4146763 TI - Some observations on the -adrenoceptor agonist properties of the isomers of salbutamol. AB - 1. The pharmacological activities of the optical isomers of salbutamol have been examined. (-)-Salbutamol was much more potent than (+)-salbutamol on beta adrenoceptors.2. Both (-)- and (+)-salbutamol showed high selectivity for beta adrenoceptors in bronchial muscle compared to cardiac muscle, in this way resembling racemic salbutamol.3. The use of isomeric activity ratio to detect differences between receptors was examined in the light of the results obtained with the isomers of salbutamol. PMID- 4146764 TI - Pharmacological analysis of the acute inflammatory process induced in the rat's paw by local injection of carrageenin and by heating. AB - 1. Local injection of carrageenin in the rat's paw produced oedema and leakage of dye which had been administered previously by the intravenous route. A net dissociation between both parameters was observed: while oedema developed slowly, maximal intensity being attained after 4-5 h, dye-leakage was maximum after 1 hour.2. Anti-inflammatory drugs such as acetylsalicylic acid and indomethacin were effective in reducing oedema and dye-leakage when given before the injection of carrageenin, but much less effective when given 30 or 60 min after carrageenin. Hexadimethrine bromide was effective in reducing dye-leakage also when given 1 h after the injection of carrageenin.3. Combined administration of benadryl and methysergide, before the injection of carrageenin caused only a slight reduction in oedema and dye-leakage.4. When the paws were heated (55 degrees C for 30 s) as a noxious stimulus the dissociation between maximal oedema and maximal dye-leakage was not observed, both phenomena running parallel. Pre treatment of the animals with indomethacin did not afford any protection.5. These results suggest that the inflammatory reaction to mild stimuli (carrageenin in our experiments) develops through different phases: initially the increased vascular permeability involves extravasation of plasma proteins and that phase is followed by an increased permeability mainly to water. Stronger stimuli (heating in our experiments) produce an overlapping of both phases, probably by inflicting severe damage to the vascular bed of the affected area.6. The anti-inflammatory drugs employed affected chiefly the initial phase of the response. PMID- 4146765 TI - Oxidation of the capsular polysaccharide of pneumococcal type IV by periodate. PMID- 4146766 TI - The clinician's approach to antiarrhythmic therapy. PMID- 4146768 TI - [Therapeutic modification of polycythemia vera by transferred anti-erythrocyte antibodies]. PMID- 4146769 TI - Role of the tear film in contact lens wear. PMID- 4146767 TI - Antiarrhythmic agents. I. Mechanisms of action and clinical pharmacology. PMID- 4146770 TI - The effects of anoxia on isozyme patterns and ultrastructure of cultured human fibroblasts. PMID- 4146771 TI - Tyrosine-alpha-ketoglutarate aminotransferase activity in rat liver after spinal cord section. PMID- 4146772 TI - Proximal contacts in posterior teeth and factors influencing interproximal caries. PMID- 4146773 TI - Current status of propranolol hydrochloride (inderal). PMID- 4146774 TI - Corticosteroids in the treatment of sunburn. PMID- 4146775 TI - Stimulant action of methoxamine in the isolated atria of normal and 6-propyl-2 thiouracil-fed rats. PMID- 4146776 TI - Studies on a new 1,5-benzothiazepine derivative (CRD-401). V. Antiarrhythmic actions. PMID- 4146777 TI - Antagonistic activity of some phenothiazine derivatives against neurohumoral transmitters. PMID- 4146778 TI - Use of hemodialysis in the treatment of quinidine poisoning. PMID- 4146779 TI - [Acute cor pulmonale in pulmonary emboli]. PMID- 4146780 TI - Collagen-induced platelet aggregation: involement of an active glycopeptide fragment (alpha1-CB5). AB - It is widely held that the tertiary structure of collagen is essential for induction of platelet aggregation. However, we have found that the purified alpha1 chain prepared from denatured chick skin collagen aggregates platelets. This activity appears to be confined to a distinct region of the molecule representing less than 4 percent of the length of the alpha1 chain. Of all of the cyanogen bromide peptides of the alpha1 chain tested, only one (alpha1-CB5) was active. This glycopeptide, devoid of any ordered tertiary structure, contains only 36 amino acids and one residue of O-alpha-D-glucopyranosyl-(1 --> 2)-O-beta D-galactopyranosyloxy-(1 --> 5)-lysine (Glc-Gal-Hyl). Blocking experiments strongly suggest that the Glc-Gal-Hyl is one of the structural determinants involved in collagen-induced platelet aggregation. PMID- 4146781 TI - The promotion of interest in the role of the physician associate as a potential career opportunity for nurses: an alternative strategy. PMID- 4146783 TI - First International Symposium and Workshop on the Polymorphism of the Third Component of the Human Complement System. Bonn, June 26-28, 1972 at the Institute of Forensic Medicine of the University, Bonn, FRG. PMID- 4146782 TI - Effects of a new cardioselective beta-adrenergic blocker (tolamolol) on exercise tolerance in patients with angina pectoris. PMID- 4146784 TI - [Injuries of the upper ankle joint]. PMID- 4146785 TI - A modification of isocitrate and malate dehydrogenase assays for use in crude cell free extracts. PMID- 4146786 TI - The cardiac effects of cocaine and certain antihistamines and antidepressants. PMID- 4146787 TI - [Competitive antagonism between isoprenalin and adrenolytic agents toward urease]. PMID- 4146788 TI - [Anti-arrhythmic effects of a beta-adrenolytic agent dl (hydroxy 2't-butylamino 3' propyloxy) 8-thiochromane (S 2395)]. PMID- 4146789 TI - [Beta adrenolytic and hemodynamic effects of dl (hydroxy 2't-butylamino 3' propyloxy) 8-thiochromane (S 2395)]. PMID- 4146790 TI - [Studies on the mechanism of action of sulfonylurea compounds. Effect of glibornuride and insulin on blood sugar, plasma catecholamines and on the immunologically determinable insulin following blockade of adrenergic receptors]. PMID- 4146791 TI - [Extrapancreatic effects of sulfonylurea compounds. V. Studies on the antilipolytic effect of glibornuride]. PMID- 4146793 TI - Action of -adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine. PMID- 4146792 TI - [The stimulating effect of hexoprenaline on various sympathetic beta-receptors]. PMID- 4146794 TI - [The effect of centrophenoxine on thiopental anesthesia]. PMID- 4146795 TI - Regulation by cytidine nucleotides of the acylation of sn-(14C)glycerol 3 phosphate. Regional and subcellular distribution of the enzymes responsible for phosphatidic acid synthesis de novo in the central nervous system of the rat. AB - 1. The regional and subcellular distribution of the incorporation of sn [(14)C]glycerol 3-phosphate into rat brain lipids in vitro was investigated and compared with the relative specific activity of various chemical and enzyme markers. The similarity between the subcellular distribution of this incorporation and of NADPH-cytochrome c reductase activity indicated that the synthesis of phosphatidic acid via this route correlated with the presence of endoplasmic reticulum. 2. Experiments in which various amounts of the microsomal fraction were added to fixed amounts of nuclear, myelin, nerve-ending and mitochondrial preparations clearly demonstrated that the endoplasmic-reticulum contamination of these fractions was entirely responsible for the incorporation of sn-[(14)C]glycerol 3-phosphate. 3. The presence of CMP or CTP inhibited the incorporation of sn-[(14)C]glycerol 3-phosphate into the whole homogenate. Similar effects were observed with individual fractions, except for the mitochondria. With the mitochondrial fraction the effect of these cytidine nucleotides varied with the preparation, stimulating in some preparations and inhibiting with other preparations. The presence of CDP-choline stimulated the incorporation into the whole homogenate and to a lesser extent into the subcellular fractions. 4. These results indicate that the various organelles of the central nervous system are more dependent on endoplasmic reticulum for the production of glycerolipids de novo than has previously been appreciated. PMID- 4146796 TI - The degradation of L-histidine, imidazolyl-L-lactate and imidazolylpropionate by Pseudomonas testosteroni. AB - 1. Imidazol-5-ylpropionate and imidazol-5-yl-lactate are degraded by Pseudomonas testosteroni via inducible pathways. 2. Growth on either compound as the sole source of carbon results in the induction of the enzymes for histidine catabolism. 3. The pathway of histidine degradation in this organism, a non fluorescent Pseudomonad, is shown to be the same as that operating in Pseudomonas fluorescens and Pseudomonas putida. It consists of the successive formation of urocanate, imidazol-4-on-5-ylpropionate, N-formimino-l-glutamate, N-formyl-l glutamate and glutamate. 4. Whole cells of P. testosteroni accumulate urocanate in the reaction mixture when incubated with imidazolylpropionate, but only after an adaptive lag period which is removed by previous growth on imidazolylpropionate as the source of carbon. 5. Imidazolyl-lactate is oxidized to imidazolylpyruvate, which then gives rise to histidine by specific transamination with l-glutamate. 6. Cells grown on histidine, urocanate or imidazolylpropionate are also able to degrade imidazolyllactate. 7. Mutants lacking urocanase are unable to grow on imidazolylpropionate, imidazolyl-lactate, histidine or urocanate. One with impaired histidase activity cannot utilize histidine or imidazolyl-lactate, but grows normally on imidazolylpropionate or urocanate. A mutant unable to grow on imidazolylpropionate is indistinguishable from the wild-type with respect to growth on histidine, imidazolyl-lactate or urocanate. 8. Thus it is established that imidazolyl-lactate is metabolized via histidine whereas imidazolylpropionate enters the histidine degradation pathway after conversion into urocanate. PMID- 4146797 TI - The control of the enzymes degrading histidine and related imidazolyl derivates in Pseudomonas testosteroni. AB - 1. The induction of the enzymes for the degradation of l-histidine, imidazolylpropionate and imidazolyl-l-lactate in Pseudomonas testosteroni was investigated. 2. The activities of histidine ammonia-lyase, histidine-2 oxoglutarate aminotransferase and urocanase are consistent with these enzymes being subject to co-ordinate control under most growth conditions. However, a further regulatory mechanism may be superimposed for histidase alone under conditions where degradation of histidine must take place for growth to occur. 3. Experiments with a urocanase(-) mutant show that urocanate is an inducer for the enzymes given above and also for N-formiminoglutamate hydrolyase and N formylglutamate hydrolase. 4. N-Formiminoglutamate hydrolase and N formylglutamate hydrolase are also induced by their substrates, and it is suggested that these two enzymes may be different gene products from those expressed in the presence of urocanate. 5. Induction of the enzyme system for the oxidation of imidazolylpropionate is dependent on exposure of cells to this compound. PMID- 4146798 TI - Insulin and the regulation of adipose tissue acetyl-coenzyme A carboxylase. AB - Rat epididymal fat-pads were incubated for 30min with glucose (2mg/ml) in the presence or absence of insulin. A twofold or greater increase in acetyl-CoA carboxylase activity was observed in extracts from insulin-treated tissue provided that assays were performed rapidly after extraction. This effect of insulin was evident whether or not extracts were prepared with albumin, and was not noticeably diminished by the presence of citrate or albumin or both in the assay. Incubation of extracts before assay led to activation of acetyl-CoA carboxylase and a marked diminution in the insulin effect. The enzyme in extracts was very sensitive to reversible inhibition by palmitoyl-CoA even in the presence of albumin (10mg/ml); inhibition persisted on dilution of enzyme and inhibitor. It is suggested that the observed activation of acetyl-CoA carboxylase by insulin may reflect changes in enzyme activity in the fat-cell resulting from the reduction of long-chain fatty-acyl-CoA that occurs in the presence of insulin. Activation of the enzyme with loss of the insulin effect on incubation of the extracts may be due to the slow dissociation of long-chain fatty acyl-CoA from the enzyme. PMID- 4146799 TI - The proton-translocating nicotinamide-adenine dinucleotide (phosphate) transhydrogenase of rat liver mitochondria. AB - 1. The NAD(P) transhydrogenase activity of the soluble fraction of sonicated rat liver mitochondrial preparations was greater than the NAD-linked isocitrate dehydrogenase activity, and the NAD-linked and NADP-linked isocitrate dehydrogenase activities were not additive. The NAD-linked isocitrate dehydrogenase activity was destroyed by an endogenous autolytic system or by added nucleotide pyrophosphatase, and was restored by a catalytic amount of NADP. 2. We concluded that the isocitrate dehydrogenase of rat liver mitochondria was exclusively NADP-specific, and that the oxoglutarate/isocitrate couple could therefore be used unequivocally as redox reactant for NADP in experiments designed to operate only the NAD(P) transhydrogenase (or loop 0) segment of the respiratory chain in intact mitochondria. 3. During oxidation of isocitrate by acetoacetate in intact, anaerobic, mitochondria via the rhein-sensitive, but rotenone- and arsenite-insensitive, NAD(P) transhydrogenase, measurements of the rates of carbonyl cyanide p-trifluoromethoxyphenylhydrazone-sensitive and carbonyl cyanide p-trifluoromethoxyphenylhydrazone-insensitive pH change in the presence of various oxoglutarate/isocitrate concentration ratios gave an - >H(+)/2e(-) quotient of 1.94+/-0.12 for outward proton translocation by the NAD(P) transhydrogenase. 4. Measurements with a K(+)-sensitive electrode confirmed that the electrogenicity of the NAD(P) transhydrogenase reaction corresponded to the translocation of one positive charge per acid equivalent. 5. Sluggish reversal of the NAD(P) transhydrogenase reaction resulted in a significant inward proton translocation. 6. The possibility that isocitrate might normally be oxidized via loop 0 at a redox potential of -450mV, or even more negative, is discussed, and implies that a P/O quotient of 4 for isocitrate oxidation might be expected. PMID- 4146800 TI - The distribution of cardioactive agents among molluscan species and tissues. PMID- 4146801 TI - Treatment of psychosis subsequent to phenothiazine-induced agranulocytosis. PMID- 4146802 TI - Norepinephrine and dopamine in the developing chick brain. PMID- 4146803 TI - [The so-called cryptorchism from surgical and andrological viewpoints]. PMID- 4146804 TI - A report on the dental health of Zambian school children in the rural and urban areas of the country. PMID- 4146805 TI - The effect of the -receptor blockade (propranolol) on the endocrine and exocrine pancreatic function in man after the administration of intestinal hormones (secretion and cholecystokinin-pancreozymin). PMID- 4146806 TI - Survival and endogenous colony formation in irradiated mice grafted with normal or infectious mononucleosis bone marrow. PMID- 4146807 TI - Effects of 2-BR-alpha-ergokryptine (CB 154) on sex-linked rejection of pituitary isografts in female C57BL mice. PMID- 4146809 TI - [Antiseborrhoic effect of bituminosulfonates in acne vulgaris]. PMID- 4146808 TI - [Effects of thyroid hormones and alpha, beta-blockers on catecholamine-induced calorigenesis, lipolysis and glycogenolysis]. PMID- 4146810 TI - Effects of iodinated contrast media on erythrocytes. II. Effect of some drugs on alterations induced by meglumine acetrizoate. PMID- 4146811 TI - The treatment of insomnia through the use of electrosleep: an EEG study. PMID- 4146812 TI - Drug effects on regional cerebral blood flow in focal cerebrovascular disease. PMID- 4146813 TI - Beta blockade in the treatment of tricyclic antidepressant overdosage. PMID- 4146815 TI - Seminar on dorsal column stimulation: summary of proceedings. PMID- 4146814 TI - The aromatization of (7 -3H) androstenedione by human placental mitochondria. PMID- 4146816 TI - Cutaneous polyarteritis nodosa and Crohn's disease. PMID- 4146817 TI - [Polyheads in T7 and Y phages]. PMID- 4146818 TI - [Characterization of viremia in rabbits infected with a neurotropic strain of vaccinia virus]. PMID- 4146819 TI - [Tick-borne encephalitis virus (TBE) in the GDR]. PMID- 4146820 TI - [Rubella 1969-1971 in Hamburg. Laboratory findings in women and in children suspect of congenital rubella or cytomegalic inclusion disease]. PMID- 4146821 TI - [UV inactivation of Herpes simplex viruses, types 1 and 2]. PMID- 4146822 TI - [Virulence and penicillin resistance of staphylococci considered amongst various criteria of bacterial pathogenicity]. PMID- 4146823 TI - Deoxyribonucleic acid base composition of staphylococci. PMID- 4146824 TI - [Anaerobic gram-positive cocci (Peptococcus variabilis, P. asaccharolyticus, P. prevotii and P. saccharolyticus) isolated from pathological material]. PMID- 4146825 TI - [Toxic-septic syndrome in infants caused by E. coli O 124:K 72 (B 17)]. PMID- 4146826 TI - [The classification and nomenclature of salmonella-species]. PMID- 4146827 TI - [A study on the epidemiology of Sarratia marcescens using bacteriocin typing]. PMID- 4146828 TI - The direct demonstration of phage microlysis in thin sections of colonies of argentinian Mycobacterium bovis strains. PMID- 4146829 TI - [Membrane lipids as possible enzyme substrates of SH-dependent bacterial cytolysins]. PMID- 4146830 TI - Antibiotic activity of polysaccharide--protein complexes isolated from different candida species. PMID- 4146831 TI - [Intestinal parasites in human excrements from prehistoric salt-mines of the Hallstatt period (800-350 B.C.)]. PMID- 4146832 TI - Studies on the suitability of sulphite cycloserine agar for the enumeration of clostridium perfringens in food and water. PMID- 4146833 TI - On the release of prostaglandin E2 from the rabbit heart following infusion of noradrenaline. PMID- 4146834 TI - [Congenital abnormalities of rectum and anus. Diagnosis, physiology and therapy]. PMID- 4146835 TI - The isocitrate dehydrogenases of Acinetobacter lwoffi. Studies on the regulation of a nicotinamide-adenine dinucleotide phosphate-linked isoenzyme. AB - Of the two NADP-linked isocitrate dehydrogenases in Acinetobacter lwoffi the higher-molecular-weight form, isoenzyme-II, is reversibly stimulated sixfold by low concentrations of glyoxylate or pyruvate. Kinetic results indicate that this stimulation of activity involves both an increase in V(max.) and a decrease in the apparent K(m) values for substrates, most markedly that for NADP(+). Other changes brought about by glyoxylate or pyruvate include a shift in the pH optimum for activity and an increased stability to inactivation by heat or urea. Mixtures of glyoxylate plus oxaloacetate, known to inhibit isocitrate dehydrogenases from other organisms, produce inhibition of both A. lowffi isoenzymes, and do not reflect the stimulatory specificity of glyoxylate for isoenzyme-II. Isoenzyme-II is also stimulated by AMP and ADP, but the activation by glyoxylate or pyruvate is shown to be quite independent of the adenylate activation. Differential desensitization of the enzyme by urea to the two types of activator further supports the view that the enzyme possesses two distinct allosteric regulatory sites. The metabolic significance of the activations is discussed. PMID- 4146836 TI - Metabolism of androst-4-ene-3,17-dione by subcellular fractions of rat adrenal tissue with particular reference to microsomal C19-steroid 5alpha-reductase. AB - The location and some characteristics of rat adrenal C(19)-steroid 5alpha reductase were investigated by using [7alpha-(3)H]androst-4-ene-3,17-dione and [7alpha-(3)H]testosterone as substrates. The enzymes system was shown to be NADPH dependent and associated with the microsomal fraction. In addition, some evidence was also obtained for the existence of a separate NADH-dependent system in the soluble fraction. Further investigation of androst-4-ene-3,17-dione metabolism by subcellular fractions indicated the presence of NADH-dependent 3alpha- and 3beta hydroxy steroid dehydrogenase systems in the microsomal pellet. This pellet also appeared to contain an NADH-dependent 17beta-hydroxy steroid dehydrogenase system, and a similar though separate system was detected in the cytosol. Malate (20mm) effectively inhibited the microsomal C(19)-steroid 5alpha-reductase, which showed similar values for K(m) and V(max.) when either androst-4-ene-3,17-dione or testosterone was used as substrate. Cytochrome c was added to all incubation mixtures used for the determination of these values to inhibit the formation of metabolites other than 5alpha-androstane-3,17-dione and 5alpha dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3-one) respectively. It was also found that corticosterone did not inhibit the 5alpha-reduction of androst-4 ene-3,17-dione under these conditions, indicating that separate enzymes exist for the 5alpha-reduction of C(19)- and C(21)-steroids in the rat adrenal. PMID- 4146837 TI - Hyperkinetic cardiovascular state in polymyositis. PMID- 4146838 TI - [Therapy of cerebral ictus by continuous intravenous perfusion of bamethan]. PMID- 4146839 TI - Tooth survival following various methods of sub-apical osteotomy. PMID- 4146840 TI - Eearly pulp changes following reduction of open bite by segmental surgery. PMID- 4146841 TI - Current trends in health care. The physician's role. PMID- 4146842 TI - Automated assay of single tablets of methdilazine and methdilazine hydrochloride. PMID- 4146843 TI - Clemmensen reduction of Mannich bases: potential ganglionic and nicotinic agents. PMID- 4146844 TI - Equilibrium geometries of three beta adrenergic blocking agents. PMID- 4146845 TI - The effects of age and sex on the biosynthesis, urinary excretion and tissue concentration of L-ascorbic acid in rats. PMID- 4146846 TI - Effect of fructose on cellular respiration in perfused rat liver. PMID- 4146847 TI - Metabolism of fructose and glyceraldehyde in the isolated perfused pig liver. PMID- 4146848 TI - The interrelationship between fructose and ethanol metabolism in the isolated perfused pig liver. PMID- 4146849 TI - The effect of fructose on hepatic synthesis of fatty acids. PMID- 4146850 TI - Ventricular function curve analysis of the myocardial effects of three beta blockers. PMID- 4146851 TI - [Phenotypic and genetic analysis of mutants resistant to amethopterin presenting a change in the anti-metabolite transport system]. PMID- 4146852 TI - Relative activities of acetyl-CoA carboxylase and fatty acid synthetase in chick liver: effects of dietary fat. PMID- 4146853 TI - An experimental screening for "systemic adjuvants of immunity" applicable in cancer immunotherapy. PMID- 4146854 TI - Immunosuppression and malignant lymphomas in graft-versus-host reactions. PMID- 4146855 TI - Immune capacity and response to antigenic tumors. PMID- 4146856 TI - Studies on glutathione reductase and regeneration of reduced glutathione in normal human adult and cord red cells. PMID- 4146857 TI - Effects of allethrin and Condylactis toxin on the kinetics of sodium conductance of crayfish axon membranes. PMID- 4146858 TI - Antagonism between bicuculline, strychnine, and picrotoxin and depressant amino acids in the rat nervous system. PMID- 4146859 TI - Seasonal variation in heart-rate-core temperature relationship in Rana pipiens: the role of the autonomic nervous system. PMID- 4146860 TI - A reappraisal of the actions of noradrenaline and 5-hydroxytryptamine on cerebral cortical neurons. PMID- 4146861 TI - The quantitative analysis of some constituents of crude sweat. II. Zinc, copper, iron, sialic acid content and oxidative activity. PMID- 4146862 TI - [Effect of anti-arrhythmic drugs on intracardiac conduction (His-bundle electrogram) and sinus-node automatism in man]. PMID- 4146863 TI - Caries experience and fluoride uptake in children receiving semiannual prophylaxes with an acidulated phosphate fluoride paste. Questionable conclusions? PMID- 4146864 TI - [Cardiodepressive side effects of beta sympatholytic therapy. Clinical tests with Visken]. PMID- 4146865 TI - [Allergic pulmonary diseases in childhood. Diagnostic and therapeutic results]. PMID- 4146866 TI - [Immunization in allergic patients. 2]. PMID- 4146867 TI - Methods of solid tumour evaluation in immunological experiment. I. Objective error in the determination of the growth curve. PMID- 4146868 TI - [Tyrosine metabolism and its relations to hypertyrosinemia states]. PMID- 4146870 TI - ACS establishes standards for surgeon's assistants. PMID- 4146869 TI - Drug reactions and sublingual testing with certified food colors. PMID- 4146871 TI - Dietary influence on antinuclear antibodies and cell-mediated immunity in NZB mice. PMID- 4146872 TI - D-alanine oxidase form Escherichia coli: localization and induction by L-alanine. AB - Dialyzed membranes of Escherichia coli prepared by an ethylenediaminetetraacetic acid-lysozyme method catalyze the oxidation of both l-alanine and d-alanine. The specific activities for the oxidations of both d-alanine and l-alanine are increased fivefold when the cells are grown in the presence of either l-alanine or dl-alanine, but are increased only slightly when grown in the presence of d alanine. In the dl-alanine-induced system, the specific activities for the oxidations of some other d-amino acids are also raised. dl-alanine also induces two other alanine catabolizing enzymes, alanine dehydrogenase and alanine glutamate aminotransferase which are found in the "soluble" fraction of lysozyme treated cells. The oxidations of both l-alanine and d-alanine were associated with the membranes of induced cells. After the membranes were disintegrated by sonic treatment, both l-alanine and d-alanine oxidation catalysts sedimented in a sucrose density gradient together with d-lactate and l-lactate dehydrogenases, apparently as a single multienzyme complex. PMID- 4146873 TI - D-alanine oxidase from Escherichia coli: participation in the oxidation of L alanine. AB - Cell wall-membrane preparations of Escherichia coli, prepared by the ethylenediaminetetraacetic acid-lysozyme method, contain enzymes which catalyze the oxidation of d-alanine and, to a lesser extent, l-alanine into pyruvate and ammonia without the formation of hydrogen peroxide. The kinetic parameters were (i) pH optima of 8.3 to 8.4 for l- and d-alanine and (ii) a K(m) value of 6.6 +/- 0.2 mM for d-alanine. Several coenzymes were without effect when added to the reaction mixture. The participation of d-alanine oxidase in the oxidation of l alanine was demonstrated. The evidence is based on (i) results of cellular fractionation; (ii) labeling experiments; (iii) inhibition studies with aminooxyacetate and cycloserine; (iv) denaturation experiments; and (v) demonstration of the presence of an active racemase. PMID- 4146874 TI - Pathway of n-alkane oxidation in Cladosporium resinae. AB - Pathways of initial oxidation of n-alkanes were examined in two strains of Cladosporium resinae. Cells grow on dodecane and hexadecane and their primary alcohol and monoic acid derivatives. The homologous aldehydes do not support growth but are oxidized by intact cells and by cell-free preparations. Hexane and its derivatives support little or no growth, but cell extracts oxidize hexane, hexanol, and hexanal. Alkane oxidation by extracts is stimulated by reduced nicotinamide adenine dinucleotide (phosphate). Alcohol and aldehyde oxidation are stimulated by nicotinamide adenine dinucleotide (phosphate), and reduced coenzymes accumulate in the presence of cyanide or azide. Extracts supplied with (14)C-hexadecane convert it to the alcohol, aldehyde, and acid. Therefore, the major pathway for initial oxidation of n-alkanes is via the primary alcohol, aldehyde, and monoic acid, and the system can act on short-, intermediate-, and long-chain substrates. Thus, filamentous fungi appear to oxidize n-alkanes by pathways similar to those used by bacteria and yeasts. PMID- 4146875 TI - [Regular General Meeting for 1973 held at Fukuoka attended by 4500 members]. PMID- 4146877 TI - [ICN congress, Mexico '73]. PMID- 4146876 TI - Sectral in the management of angina pectoris. PMID- 4146878 TI - [Studies on the monoamine oxidase inhibiting properties of imidazole derivatives]. PMID- 4146879 TI - [Medical problems in automobile driving following surgical interventions with local anesthesia under beta receptor blockade]. PMID- 4146880 TI - Antibodies to an extract of Streptococcus mutans, containing glucosyltransferase activity, related to dental caries in man. PMID- 4146881 TI - The part played by the trans-septal fibre system in experimental approximal drift of the cheek teeth of monkeys (Macaca irus). PMID- 4146882 TI - Effects of drugs on the nose and middle ear. Lessons from an animal model. PMID- 4146883 TI - Epidemiology of traumatic dental injuries to primary and permanent teeth in a Danish population sample. PMID- 4146884 TI - Application of a new chemically bonded, superficially porous anion-exchange packing to nucleotide analysis. PMID- 4146885 TI - Health manpower development and rural services. PMID- 4146886 TI - The management of hypertension. PMID- 4146887 TI - Enzymatic reduction of "biogenic" aldehydes in brain. PMID- 4146888 TI - Production of antibodies to bovine adrenal tyrosine hydroxylase: cross-reactivity studies with other pterin-dependent hydroxylases. PMID- 4146889 TI - Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. I. Effects of activation and inhibition of the fatty acyl coenzyme A desaturation system. PMID- 4146890 TI - Reduced diphosphopyridine nucleotide synergism of the reduced triphosphopyridine nucleotide-dependent mixed-function oxidase system of hepatic microsomes. II. Role of the type I drug-binding site of cytochrome P-450. PMID- 4146891 TI - Choline acetylase and glutamic acid decarboxylase in Huntington's chorea. A preliminary study. PMID- 4146892 TI - Non-esterified fatty acids, serum insulin and blood glucose after a beta-receptor blocking agent in normal, hypophysectomized, diabetic and hypophysectomized diabetic dogs. PMID- 4146893 TI - Testosterone metabolism in slices and subcellular fractions of human liver. PMID- 4146894 TI - Metabolism of 5alpha-dihydrotesterone in the rat prostate. PMID- 4146895 TI - 5Alpha-steroid reductase in human fetal brain. PMID- 4146896 TI - Enzymes of androgen metabolism in human leucocytes. PMID- 4146897 TI - The effect of gonadotropins on the "androgen status" in boys with undescended testes. PMID- 4146898 TI - The mosquito: still man's worst enemy. PMID- 4146899 TI - The dietary control of the microsomal stearyl CoA desaturation enzyme system in rat liver. PMID- 4146900 TI - Phosphorus-31 nuclear magnetic resonance studies of the phosphonate and phosphate composition of the sea anemone, Bunadosoma, sp. PMID- 4146901 TI - Kinetics of binding of reduced nicotinamide adenine dinucleotide phosphate to the rat liver fatty acid synthetase complex. PMID- 4146902 TI - [Circulatory effects of a new specific beta adrenergic blocking agent, (o-(2 hydroxy-3-(tert. butylamino)-propoxyl)-benzonitrile, Ko 1366)]. PMID- 4146903 TI - Pharmacological properties of ((3alpha-tropanyl)oxy)-5H-benzo(4,5)cycloheptal(1,2 b)-pyridine hydrogen maleate (BS 7723). PMID- 4146904 TI - Comparison of the responses of density gradient separated lymphocytes to phytohemagglutinin and histocompatibility antigens. PMID- 4146905 TI - Detection of nonspecific cytotoxicity in graft-versus-host reaction as a function of target cell type. PMID- 4146906 TI - On model building in structure-activity relationships. A reexamination of adrenergic blocking activity of beta-halo-beta-arylalkylamines. PMID- 4146907 TI - Preparation and cardiovascular actions of a group of tetrahydroisoquinoline derivatives. PMID- 4146908 TI - Occurrence of Mycobacterium leprae in arthropods. PMID- 4146910 TI - [ICN Congress in Mexico City]. PMID- 4146909 TI - Catecholamine and dibutyryl cyclic AMP effects on myosin adenosine triphosphatase in cultured rat heart cells. AB - Catecholamines and dibutyryl adenosine 3', 5'-monophosphate (dibutyryl cyclic AMP) increase the activity of myosin adenosine triphosphatase in cultured rat heart cells. Dichloroisoproterenol, an inhibitor of the beta receptor of the catecholamines, inhibits the action of the catecholamines but not of cyclic AMP. PMID- 4146911 TI - [Dithiaden]. PMID- 4146912 TI - A comparative study of the absorption of xanthinol nicotinate from slow-release and plain tablets in man. PMID- 4146913 TI - Some aspects of aviation physiology. PMID- 4146914 TI - Nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase of Neurospora. I. Isolation, subunits, amino acid composition, sulfhydryl groups, and identification of a lysine residue reactive with pyridoxal phosphate and N ethylmaleimide. PMID- 4146915 TI - Role of pyruvate carboxylase, phosphoenolpyruvate carboxykinase, and malic enzyme during growth and sporulation of Bacillus subtilis. PMID- 4146917 TI - Metabolism of 3-beta-hydroxy-5-ene steroids by testes of rats acclimatized to a hot environment. PMID- 4146918 TI - [Fate of the second twin]. PMID- 4146916 TI - Regulation of the synthesis of enzymes responsible for glutamate formation in Klebsiella aerogenes. PMID- 4146919 TI - The role of dietary protein in generating daily rhythms in rat liver tryptophan pyrrolase and tyrosine transaminase. PMID- 4146920 TI - [Compounds with antiarrhythmic effects]. PMID- 4146921 TI - [Significance of adenosine-3',5'-monophosphate for the effects of various hormones and drugs on metabolism]. PMID- 4146922 TI - Uses and misuses of anti-inflammatory drugs in racehorses. 1. PMID- 4146923 TI - Urinary excretion of phenothiazine tranquillisers by the horse. PMID- 4146924 TI - Multidimensional analysis of subjective symptomatology during prolonged strenuous exercise. PMID- 4146925 TI - [DMF index in the normal population]. PMID- 4146926 TI - Immune surveillance of lymphoid tissue. A biological role for the mixed lymphocyte reaction. PMID- 4146927 TI - Replicated correlations of MMPI two-point code types: the Missouri actuarial system. PMID- 4146928 TI - Endorsement of Ellis' irrational beliefs as a function of psychopathology. PMID- 4146929 TI - Primary affective disorder: MMPI differences between unipolar and bipolar depressed subjects. PMID- 4146930 TI - The Mini-Mult and its use with adolescents. PMID- 4146931 TI - Stages of schizophrenic decompensation and reintegration. PMID- 4146932 TI - [Hypoxic pulmonary vascular constriction. I. Effects of beta-adrenergic receptor stimulation and blockade]. PMID- 4146933 TI - [Symposium I. 1. Clinical manifestations and diagnosis of juvenile rheumatoid arthritis]. PMID- 4146934 TI - [Symposium I. 2. Treatment in the field of internal medicine and prognosis of juvenile rheumatoid arthritis]. PMID- 4146935 TI - [Neuropsychological studies in hyperventilation tetany]. PMID- 4146936 TI - Psychoactive drug-induced changes of interhemispheric EEG amplitude relationships. PMID- 4146937 TI - Effect of cyclophosphamide on a local graft-versus-host reaction in the rat: influence of sex, disease and different dosage regimens. PMID- 4146938 TI - Disk test for the differentiation of pneumococci from other alpha-hemolytic streptococci. AB - One hundred twenty-five strains of Diplococcus pneumoniae and one hundred twenty five strains of other alpha-hemolytic streptococci were planted on horse red cell Brucella agar, and a disk of methicillin was placed on each inoculated plate. All strains were incubated anaerobically at 37 C for 24 h and then exposed to air at 6 C for 48 h. All strains of pneumococci produced a ring of beta-hemolysis surrounding the zone of inhibition produced with the methicillin disk, whereas no strain of alpha-hemolytic streptococci produced beta-hemolysis. It is suggested that this new criterion is useful for the differentiation of pneumococci from other alpha-hemolytic streptococci in those cases where other characteristics were insufficient for an unequivocal identification. PMID- 4146939 TI - The effect of experimentally induced redox changes on human rheumatoid and non rheumatoid synovial tissue in vitro. PMID- 4146940 TI - Drug therapy in the elderly. PMID- 4146941 TI - [Influence of beta-adrenergic blockade on plasma renin activity]. PMID- 4146943 TI - Personality correlates of venereal disease experience. PMID- 4146942 TI - Treatment of cardiogenic shock. I. PMID- 4146944 TI - A device for the mounting and manipulation of small protein crystals. PMID- 4146945 TI - Testicular enzymes and spermatogenesis. PMID- 4146946 TI - [Current status in the therapy of cryptorchism]. PMID- 4146947 TI - Spectrophotometric studies of the mechanism of photosynthesis. PMID- 4146948 TI - [Value of electromyography in rheumatoid arthritis, major collagen disease and iatrogenic myopathies]. PMID- 4146949 TI - Metabolites of Serc and interaction of Serc with antihistamines. PMID- 4146950 TI - "How should a treatment of Meniere's syndrome be evaluated?" Panel discussion. PMID- 4146951 TI - Early arrhythmias following experimental coronary occlusion in conscious dogs and their modification by beta-adrenoceptor blocking drugs. PMID- 4146952 TI - [Value of a new antihistaminic in adaptation and tolerance of any contact lenses]. PMID- 4146953 TI - [Lung Mechanics Group of the European Society for Clinical Physiology of Respiration]. PMID- 4146954 TI - An approach to the evaluation of oral antihistaminic preparations using inhibitory action of histamine skin response in dogs. PMID- 4146955 TI - [Current anti-arrhythmic treatments and drugs]. PMID- 4146956 TI - [Gamma glutamyl transpeptidase]. PMID- 4146957 TI - [Effect of electrolytes on the extraction of pachycarpine from acidic and alkaline aqueous solutions with organic solvents]. PMID- 4146958 TI - Non-specific inhibition of the precipitin reaction between teichoic acids and antisera. PMID- 4146959 TI - Quantitative studies of the specificity of anti-pneumococcal polysaccharide antibodies, types 3 and 8. V. Cross-reacting antibodies in rabbit antisera. PMID- 4146960 TI - Non-hemorrhagic arthus reaction and its independence from circulating antibodies and complement. PMID- 4146961 TI - Pharmacological properties of a proposed mediator of dealyed hypersensitivity reactions. PMID- 4146962 TI - [Effect of a new oral remedy for a cold (HSP 525 A) on flow resistance of the nose]. PMID- 4146963 TI - [Determination of gamma-glutamyl transpeptidase and its clinical significance in various heart diseases]. PMID- 4146964 TI - [Gamma-glutamyl transpeptidase and liver diseases]. PMID- 4146965 TI - [Clinical significance of gamma-glutamyl transpeptidase]. PMID- 4146966 TI - [Significance of gamma-glutamyl transpeptidase in surgery]. PMID- 4146967 TI - [Histochemical investigation of gamma-glutamyl transpeptidase in liver diseases]. PMID- 4146968 TI - [Gamma-glutamyl transpeptidase in tumor-bearing animals]. PMID- 4146970 TI - Why not train your own assistant? PMID- 4146969 TI - Nonantipsychotic phenothiazines and tardive dyskinesia. PMID- 4146971 TI - [Use of cardioselective beta adrenergic blockaders in the treatment of circulatory failure]. PMID- 4146972 TI - Ambulatory care and rehabilitation in COPD. PMID- 4146973 TI - [A familial case of 17 r ring-shaped chromosome of group E with transmission from father to son]. PMID- 4146974 TI - [Effect of the benzohexonin-galvanomud therapy on the course of uncomplicated forms of ulcer disease of the stomach and duodenum]. PMID- 4146975 TI - Stimulation of sympathetic nerve fibres to the nose in cats. PMID- 4146976 TI - A national nutrition policy and program. PMID- 4146977 TI - Personality characteristics of servicemen returned from Viet Nam identified as heroin abusers. PMID- 4146978 TI - The diagnostic decision-making process: factors influencing diagnosis and changes in diagnosis. PMID- 4146979 TI - Patterns of professional activities of psychiatrists: a follow-up of 100 psychiatric residents. PMID- 4146980 TI - Epidemiological studies of women prisoners. I. Medical and psychiatric variables related to violent behavior. PMID- 4146981 TI - [The periods of embryogenesis and postnatal ontogenesis in man and animals]. PMID- 4146982 TI - Perinatal development of hepatic microsomal mixed function oxidase activity in swine. PMID- 4146983 TI - Formation of catecholamines from phenylalanine in brain--effects of chlorpromazine and catron. PMID- 4146984 TI - Oxidative demethylation of 14C-griseofulvin by liver microsomes of rats and mice. PMID- 4146986 TI - Central effects of alpha-adrenergic blocking agents on thermoregulation against venous blood-stream cooling in unanesthetized rabbits. PMID- 4146985 TI - Separation of soluble denitrifying enzymes and cytochromes from Pseudomonas perfectomarinus. PMID- 4146987 TI - Latency and sedimentability of acid hydrolases in sterile septa homogenates of Cerianthus lloydi G. PMID- 4146989 TI - [Dental caries prevalence and past dental treatment in young adult Israelis of different ethnic origin]. PMID- 4146988 TI - Trimethylamine oxidase of nurse shark liver and its relation to mammalian mixed function amine oxidase. PMID- 4146990 TI - Significance of cholesterol esters as liquid crystal in human atherosclerosis. PMID- 4146991 TI - Study on the transport of fatty acids in the arterial wall. PMID- 4146992 TI - The suppressive activities of alprenolol against deslanoside-induced cardiotoxicities in guinea pigs. PMID- 4146993 TI - An indirect action of papaverine in smooth muscle in vivo. PMID- 4146994 TI - Presence of histamine H2-receptors in the guinea-pig pulmonary vascular bed. PMID- 4146996 TI - Determination of salicylazosulphapyridine in biological materials. PMID- 4146995 TI - [Complications of immunosuppressive therapy using cytostatics in autoaggression diseases with special reference to cholestatic hepatosis]. PMID- 4146997 TI - Determination of free and acetylated 5-aminosalicylic acid in serum and urine after administration of salicylazosulphapyridine. PMID- 4146998 TI - Observations on the ontogeny of the feeding response to adrenergic agonists and antagonists. PMID- 4146999 TI - Personality disorder and reactive hypoglycemia. A quantitative study. PMID- 4147001 TI - Role of phenothiazine compounds in the prevention of experimental pulmonary oedema. PMID- 4147000 TI - Function of peroxidase and NADPH cytochrome C reductase during the Wolff-Chaikoff effect. PMID- 4147002 TI - Structure of deoxyribonucleic acid on the cell surface during uptake by pneumococcus. AB - We exposed competent cells of Diplococcus pneumoniae to high-molecular-weight donor deoxyribonucleate (DNA) and examined the state of the DNA bound to them in forms sensitive to deoxyribonuclease I. The portion elutable with 5 M guanidine hydrochloride was shown to be native, of much lower molecular weight (4 x 10(6) to 5 x 10(6)) than the donor, and as active in further transformation as sheared DNA of the same size. The portion resistant to release by guanidine hydrochloride was also shown to be native and active in transformation. These results, along with previous ones, imply that the breaks produced outside the cell are not at genetically specific sites. Furthermore, it was found that entry past the cell barrier to deoxyribonuclease could occur at 0 C by a process sensitive to ethylenediaminetetraacetate. PMID- 4147003 TI - tyrR, a regulatory gene of tyrosine biosynthesis in Salmonella typhimurium. AB - 4-Fluorophenylalanine-resistant mutants of Salmonella typhimurium were isolated in which tyrosine pathway enzymes were not repressed by l-tyrosine. The mutants produced elevated levels of 3-deoxy-d-arabinoheptulosonic acid 7-phosphate (DAHP) synthetase (tyr) and chorismate mutase T-prephenate dehydrogenase, and these enzymes as well as transaminase A were not repressed by high concentrations of tyrosine. Genetic analysis revealed that a mutation in a gene designated tyrR was responsible for the constitutivity of the tyrosine pathway enzymes in strains SG1, SG7, and SG9, and that tyrR was linked to pyrF. In strain SG1 a mutation had also occurred in aroF, the structural gene for DAHP synthetase (tyr), resulting in loss of sensitivity of this enzyme to end-product inhibition. There appeared to be no relationship between loss of feedback inhibition and loss of end-product repression, since derivative strains of SG1 that carried only the tyrR mutation behaved like the singly mutated tyrR strains, SG7 and SG9, in showing high constitutive levels of tyrosine-specific enzymes that were not repressed by tyrosine. PMID- 4147004 TI - Effects of hycanthone and two of its chlorinated analogs on hepatic microsomes. PMID- 4147006 TI - Xenobiotic accumulation and metabolism by isolated perfused rabbit lungs. PMID- 4147005 TI - The bronchodilator and cardiac stimulant effects of Thll65a, salbutamol and isoproterenol. PMID- 4147007 TI - Present status of treatment of chronic cor pulmonale with congestive failure. PMID- 4147008 TI - Hemodynamic characteristics of the centrally mediated pressor activities of angiotensin. PMID- 4147009 TI - Thymus-dependent functions of mouse thymocyte-fibroblast hybrid cells. PMID- 4147010 TI - Control of growth hormone secretion in man. PMID- 4147011 TI - An antihistamine-sympathomimetic amine combination in vasomotor rhinitis. PMID- 4147012 TI - Reports from the general practitioner research group. Antihistamine and phenothiazine compared in vertigo. PMID- 4147013 TI - [Therapy of banal rhinitis. Double-blind controlled clinical study]. PMID- 4147014 TI - MMPI changes for a male alcoholic state hospital population--1959 to 1971. PMID- 4147015 TI - Judged frequency of endorsement and frequency of occurrence scale values and dispersions for MMPI items. PMID- 4147016 TI - [Effect of gamma-radiation of seeds on the reducing function of the photosynthetic apparatus]. PMID- 4147017 TI - The abortive lives of modern inhalation anesthetics. PMID- 4147018 TI - Changes in hepatic free NAD and NADP levels in rats fed a hypercholesterolaemic diet. PMID- 4147019 TI - Modified erythrocyte cation permeability. PMID- 4147020 TI - Differentiation of receptors activated by catecholamines. 3. PMID- 4147021 TI - Predictable variability in the response of two newt subspecies (D. v. viridescens and D. v. dorsalis) to first-set allografts. PMID- 4147022 TI - Relationship between proliferative and effector phases of the mixed lymphocyte reaction and graft-vs-host reaction. PMID- 4147023 TI - [Serum gamma-glutamyl transpeptidase activity in normal subjects]. PMID- 4147024 TI - Congenital defects in Finnish calves. PMID- 4147025 TI - [Acute wounds on horses' limbs]. PMID- 4147026 TI - The immunosuppressive activity of ara-C (cytarabine) and derivatives. PMID- 4147027 TI - Immunosuppressive enzymes. PMID- 4147029 TI - Human peripheral lymphocytes and long-term cultured lymphoblastoid cells in local graft-versus-host reaction. PMID- 4147028 TI - Bone marrow transplantation in immunosuppressed or congenitally immune deficient patients. PMID- 4147030 TI - Graft versus leukemia. 3. Apparent independent anthost and antileukemia activity of transplanted immunocompetent cells. PMID- 4147031 TI - Graft-versus-host-induced immunosuppression. The effect of antigenic stimulation on cell-mediated and humoral immune responses. PMID- 4147032 TI - [Changes in effort tolerance in patients with coronary arterial disease following administration of 4 beta-adrenolytic agents (propranolol, visken, oxyprenolol and practolol)]. PMID- 4147033 TI - Glutamate dehydrogenases in Neisseria meningitidis. PMID- 4147034 TI - Glutamate dehydrogenases in genus Neisseria. PMID- 4147035 TI - [Case of allergy to Argas reflexus bites]. PMID- 4147036 TI - Fluroxene and animal toxicity studies. PMID- 4147037 TI - Action of catecholamines and anti-adrenergic drugs on isolated short-circuited frog skin. PMID- 4147038 TI - Action of serotonin on gastric (proventriculus) secretion in chickens. PMID- 4147040 TI - Metabolism of N'-(4-chloro-o-tolyl)-N,N-dimethylformamidine (chlorphenamidine) and 4'-chloro-o-formotoluidide by rat hepatic microsomal and soluble enzymes. PMID- 4147039 TI - The role of catecholamines and 5-hydroxytryptamine on the heart of Patella vulgata. PMID- 4147041 TI - Catecholamines in arthropods: a review. PMID- 4147042 TI - Specificity of feeding chemoreceptors in Palythoa psammophilia (Zoanthidea, Coelenterata). PMID- 4147043 TI - Neurohumoral regulation and the pharmacology of a molluscan heart. PMID- 4147044 TI - Dopamine receptors: a review. PMID- 4147045 TI - Histamine and histamine-like substances in the marine sponge, Suberites inconstans. PMID- 4147046 TI - World neurosurgery: a personal history of a surgical specialty. PMID- 4147047 TI - The reflection of ejecting and retaining currents in the time-course of neuronal responses to microelectrophoretically applied drugs. PMID- 4147048 TI - The effects of changes in ionic environment and modification of adrenergic function on the vascular responses to sympathomimetic amines. PMID- 4147049 TI - The ganglion blocking and vagolytic actions of three short-acting neuromuscular blocking drugs in the cat. PMID- 4147050 TI - The effect of corticosterone on extraneuronal amine uptake and effector response in rat salivary glands. PMID- 4147051 TI - Interactions between oxotremorine and inhibitors of cholinesterase enzymes. PMID- 4147052 TI - Spectrophotofluorometric and gas-liquid chromatographic methods for the estimation of mexiletine (Ko 1173) in plasma and urine. PMID- 4147053 TI - Quantitation of 1-tetrahydrocannabinol in plasma from cannabis smokers. PMID- 4147054 TI - The recovery of bacteria from white soft paraffin. PMID- 4147055 TI - Alkaloids from the seeds of Strychnos wallichiana Steud. ex DC. (Strychnos cinnamomifolia Thwaites var. wightii A. W. Hill). PMID- 4147056 TI - Total and free-plasma tryptophan concentrations in rheumatoid disease. PMID- 4147057 TI - Uptake of (3H)5-hydroxytryptamine and (3H)noradrenaline by slices of rat brain incubated in plasma from patients treated with chlorimipramine, imipramine or amitroptyline. PMID- 4147058 TI - The role of norfenfluramine in fenfluramine-induced mydriasis. PMID- 4147059 TI - MAO-inhibitory properties of anorectic drugs. PMID- 4147060 TI - Depression of ganglionic transmission by normetadrenaline. PMID- 4147061 TI - Further evidence in support of a common adrenergic mechanism for the facilitatory action on learning of amphetamine and nicotine in rats. PMID- 4147062 TI - Effects of ethanol on cerebral cortical neurons: interactions with some putative transmitters. PMID- 4147063 TI - Restoration of morphine analgesia in morphine-tolerant rats after the intraventricular administration of 6-hydroxydopamine. PMID- 4147064 TI - Dopamine-induced relaxation of isolated arterial strips. PMID- 4147066 TI - Deacetylation of acetyl sulphapyridine in man. PMID- 4147065 TI - Effects of diethyldithiocarbamate and ethanol on the in vivo metabolism and pharmacokinetics of amphetamine in the rat. PMID- 4147067 TI - Subtalar dislocation of the foot. PMID- 4147068 TI - Treatment of exercise-induced dysrhythmias in patients with pacemakers. PMID- 4147069 TI - [Several examples of gas-liquid chromatographic analysis of fatty acids]. PMID- 4147070 TI - [Application of gas chromatography in the study of lipid metabolism in children]. PMID- 4147071 TI - [Gas-chromatography of steroid metabolites]. PMID- 4147072 TI - [Gas chromatography of steroids--methods in laboratory diagnosis]. PMID- 4147073 TI - [Gas chromatography of aliphatic amines and its clinical application]. PMID- 4147074 TI - Diminished in vitro toxic effect of phytohaemagglutinin for lymphocytes of rats bearing syngeneic tumours. PMID- 4147075 TI - Activity of reticuloendothelial system in methylcholanthrene-induced and transplanted tumour-bearing rats. PMID- 4147076 TI - Superinfections in the antibiotic era. PMID- 4147077 TI - Unusual manifestations of periarteritis nodosa. PMID- 4147078 TI - Changes on recovery in the concentrations of tryptophan and the biogenic amine metabolites in the cerebrospinal fluid of patients with affective illness. PMID- 4147079 TI - The induction of a carcinogen-metabolizing enzyme in human skin. PMID- 4147080 TI - A kinetic study of -acetohydroxy acid isomeroreductase from Salmonella typhimurium. PMID- 4147081 TI - The effect of o-diphenols upon the microsomal NADPH and NADH oxidase activities. PMID- 4147082 TI - A microsomal fatty acid synthetase coupled to acyl-CoA reductase in Euglena gracilis. PMID- 4147083 TI - Regular dental care in dentate persons. An assessment. PMID- 4147084 TI - Caries experience relative to individual susceptibility. PMID- 4147085 TI - Fluoride in the prevention of dental caries. A tentative cost-benefit analysis. PMID- 4147086 TI - Excitatory and inhibitory innervation of the urinary bladder and gonads of a teleost, Gadus morhua. PMID- 4147087 TI - Effects of reserpine on nervous control of heart-rate in chickens (Gallus domesticus). PMID- 4147088 TI - Neurological involvement in the Smith-Lemli-Opitz syndrome: clinical and neuropathological findings. PMID- 4147090 TI - Heterogeneity of NADPH-dependent aldehyde reductase from human and rat brain. PMID- 4147089 TI - Lipid peroxidation of rat-liver microsomes. Its effect on the microsomal membrane and some membrane-bound microsomal enzymes. PMID- 4147091 TI - Reduced pyridine-nucleotides balance in glucose-growing Saccharomyces cerevisiae. PMID- 4147092 TI - Effect of dimethylaminoethyl p-chlorophenoxyacetate on the life span of male Swiss Webster Albino mice. PMID- 4147093 TI - Enzymatic hydroxylation of anthranilamide in rat liver. PMID- 4147094 TI - Lack of immediate response of liver thyrosine-alpha-ketoglutarate transaminase to exogenous adrenaline in the adrenalectomized rat. PMID- 4147095 TI - The influence of antistine on glycogenolytic effect of some biogenic amines in rat brain slices. PMID- 4147096 TI - Mitochondrial NAD-dependent malic enzyme: a new regulatory enzyme. PMID- 4147097 TI - Collagen heterografts for bone replacement. A preliminary report. PMID- 4147098 TI - Salt activity and osmotic pressure in connective tissue. I. A study of solutions of dextran sulphate as a model system. PMID- 4147099 TI - Transmitter release induced by injection of calcium ions into nerve terminals. PMID- 4147101 TI - Preparation of prostaglandins A2, E2 and 11-epi-E2 from their 15 acetates methyl esters using an endogenous enzyme system present in Plexaura homomalla (esper). PMID- 4147100 TI - Inhibition of prostaglandin induced uterine activity in the second trimester of pregnancy by beta-mimetic adrenergic agents. PMID- 4147103 TI - N-of-one and N-of-two research in psychotherapy. PMID- 4147102 TI - Repression-sensitization: a critique of some neglected variables in the literature. PMID- 4147104 TI - Studies on the mechanism underlying the enchanced noradrenaline-overflow from the rabbit heart induced by the beta-adrenolytic drugs bupranolol and pindolol. PMID- 4147105 TI - [Dopamine and the parkinsonism-chorea antagonism]. PMID- 4147106 TI - [Psychophysiological characteristics of the activity of the pilot staff of military aviation transport on flights at low altitudes]. PMID- 4147107 TI - Prescribing for patients with depression, anxiety and insomnia. PMID- 4147108 TI - Drug-induced hemolysis. PMID- 4147109 TI - Alterations of cardiac sympathetic neurotransmitter activity in congestive heart failure. PMID- 4147110 TI - Management of severe hypertension. PMID- 4147111 TI - Gravlee Jet Washer effectiveness as performed by obstetric-gynecologic paramedical personnel. PMID- 4147112 TI - Histochemical study of so-called "marker enzymes of cholestasis" during extrahepatic bile duct obstruction in the rat. PMID- 4147113 TI - Interaction of drugs and steroids with human placental microsomes. PMID- 4147114 TI - Digitoxigenin metabolism by rat liver microsomes and its induction by phenobarbital. PMID- 4147115 TI - Role of L-ascorbic acid on detoxification of histamine. PMID- 4147116 TI - Effects of colicin A and staphylococcin 1580 on amino acid uptake into membrane vesicles of Escherichia coli and staphylococcus aureus. PMID- 4147117 TI - Comparison of two cardioselective beta-adrenergic blocking agents: effects on haemodynamic and atrioventricular conduction in man. PMID- 4147118 TI - Orchiolysis: correction of the undescended testicle without fixation. PMID- 4147119 TI - Introduction of new therapeutic drugs in the United States and Great Britain: an international comparison. PMID- 4147120 TI - Metabolism of salicylazosulfapyridine in healthy subjects and in patients with ulcerative colitis. Effects of colectomy and of phenobarbital. PMID- 4147121 TI - Formation of a 16,17-trans-glycolic metabolite from a 16-dehydro-androgen in human fetal liver microsomes. PMID- 4147122 TI - Comparison of activities of drug-metabolizing enzymes in human fetal and adult livers. PMID- 4147123 TI - Effect of trimepranol, a beta blocker, on plasma levels of growth hormone, insulin, glucose, and free fatty acids. PMID- 4147124 TI - Guanyl cyclase in rat brain subcellular fractions. PMID- 4147125 TI - [Children of endogenically depressive parents--studies on the occurrence of behavior disorders and on personality structure]. PMID- 4147126 TI - Bacterial variants in central nervous system infections in infants and children. PMID- 4147127 TI - Rapid death in childhood. PMID- 4147128 TI - Pre-morbid adjustments, schizoid personality and onset of illness as predictors of post-hospitalization functioning. PMID- 4147129 TI - Rural Physicians Associate Program 1971-1972. PMID- 4147130 TI - Fracture conference. Puncture wounds of the foot. PMID- 4147131 TI - Radioimmunoassay for the cyclic nucleotides. PMID- 4147132 TI - Organization of the outer synaptic layer in the retina of the larval tiger salamander. PMID- 4147133 TI - Human histocompatibility antigens and susceptibility to disease. PMID- 4147134 TI - American Association of Medical Assistants. PMID- 4147135 TI - The kinetics of formation and sensitivity to interferon of viral intermediates appearing in chick cells infected with Semliki Forest virus. PMID- 4147136 TI - The effect of cytosine-arabinoside on the multiplication of cytomegalovirus and on the formation of virus-induced intracellular antigens. PMID- 4147137 TI - Dependence of antiviral activity on molecular weight in an interferon stimulator of the natural double-stranded RNA type. PMID- 4147138 TI - Interference between A2 and B influenza viruses and adenovirus in cell culture. PMID- 4147139 TI - Interferon tolerance and antiviral protection in mice given single or multiple injections of endotoxin or poly I : C. PMID- 4147140 TI - In vivo studies of infectious influenza virus-antibody complex. PMID- 4147141 TI - Pathogenicity of laboratory-maintained and low-passaged strains of Herpesvirus hominis in suckling mice. A comparative fluorescent antibody study. PMID- 4147142 TI - Viscerotropism of rabies-like strains isolated from murine rodents. PMID- 4147143 TI - Some properties of maize rough dwarf virus subviral particles. PMID- 4147144 TI - Susceptibility of Aedes albopictus mosquito cell line to some arboviruses. PMID- 4147145 TI - Sedimentation and buoyant density characteristics of influenza virus ribonucleoprotein. PMID- 4147146 TI - Use of the sodium deoxycholate sensitivity test in cell cultures. PMID- 4147147 TI - Growth of California group viruses in tissue fragments. PMID- 4147148 TI - The highly attenuated E5"14" plaque-cloned derivative from the Langat TP21 E5 strain. Isolation and properties. PMID- 4147149 TI - Competative inhibition of haemagglutination of tick-borne encephalitis virus by receptor-analogue substances. PMID- 4147150 TI - Response of brain amino acids to drugs and environmental conditions. PMID- 4147151 TI - The physician assistant in anesthesiology? PMID- 4147152 TI - The primary processes of photosynthesis. PMID- 4147153 TI - Studies of anaesthesia in relation to hypertension. V. Adrenergic beta-receptor blockade. PMID- 4147155 TI - Pneumococci with increased resistance to penicillin. PMID- 4147154 TI - Oral atropine and practolol premedication in dental anaesthesia. PMID- 4147156 TI - Transmitters and reticulospinal neurons. PMID- 4147157 TI - Influences of phenylephrine and orciprenaline on the release of noradrenaline. PMID- 4147158 TI - Photoinactivation of porcine D-amino acid oxidase with flavin adenine dinucleotide. PMID- 4147159 TI - Methotrexate binding to dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli. PMID- 4147160 TI - Evidence for two reduced triphosphopyridine nucleotide binding sites on dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli. PMID- 4147161 TI - Pneumococcal Forssman antigen. A choline-containing lipoteichoic acid. PMID- 4147162 TI - Identification and structure of a novel flavin prosthetic group associated with reduced nicotinamide adenine dinucleotide dehydrogenase from Peptostreptococcus elsdenii. PMID- 4147163 TI - Effects of neutral aminoacids injected into cerebrospinal fluid space on glucose metabolism in the rat brain. PMID- 4147164 TI - The role of biogenic amines in the reserpine-induced alteration of minimal electroshock seizure thresholds in the mouse. PMID- 4147165 TI - Anticholinergic poisoning: treatment with physostigmine. PMID- 4147166 TI - [Permanent teeth with reduced pulp cavity following accidental injury. A clinical and radiographic study]. PMID- 4147167 TI - Cancer in the new-born. PMID- 4147168 TI - Chemotherapy of solid tumors. PMID- 4147169 TI - L-tryptophan inhibition of tyrosine aminotransferase degradation in rat liver in vivo. PMID- 4147170 TI - Stearyl-CoA desaturase of bovine mammary microsomes. PMID- 4147171 TI - Reduced pyridine nucleotide-dependent N-hydroxy amine oxidase and reductase activities of hepatic microsomes. PMID- 4147172 TI - Plasma levels of anticonvulsants. PMID- 4147173 TI - Workshop on paediatric education. XII. International Congress of Pediatrics, Mexico City, November 30, 1968: working document. PMID- 4147174 TI - Aromatic amino acid metabolism in brindled (Mobr) and viable-brindled (Movbr), two alleles at the mottled locus in the mouse. PMID- 4147175 TI - Nicotinamide adenine dinucleotide as substrate of the nucleotide phosphotransferase from Escherichia coli. PMID- 4147176 TI - The graft-versus-host reaction to minor alloantigens. PMID- 4147177 TI - A theoretical note on personality characteristics of heroin addicts. PMID- 4147178 TI - MMPI characteristics of college freshman males who later became alcoholics. PMID- 4147179 TI - Automated fluorometric analysis of reserpine and syrosingopine tablets, using a vanadium pentoxide reagent. PMID- 4147180 TI - The pharmacotherapy of Parkinsonism. PMID- 4147181 TI - [A case of peripheral neuropathy during terminal ileitis. Crohn's disease?]. PMID- 4147182 TI - [Biosynthesis of the macrolide antibiotic A 6599 by Streptomyces hydroscopicus JA 6599 and activity of the NADP-dependent metabolism]. PMID- 4147183 TI - Saturated fatty acid biosynthesis and its regulation. PMID- 4147184 TI - Insecticide biochemistry. PMID- 4147185 TI - Comparative biochemistry of nitrogen fixation. PMID- 4147186 TI - Bacterial cell surface polysaccharides. PMID- 4147187 TI - Immunochemical evidence for the participation of cytochrome b5 in microsomal stearyl-CoA desaturation reaction. PMID- 4147188 TI - Hereditary influence on the normal personality using the MMPI. I. Age-corrected offspring resemblances.. PMID- 4147190 TI - The effect of -adrenoceptor blockade on human sweating. AB - 1. Changes in cutaneous water loss were followed by continuously monitoring total body weight loss.2. Sweating was induced in normal subjects by raising the environmental temperature or by subjecting them to the emotional stress of mental arithmetic.3. Propranolol in a dosage of 0.15 mg/kg body weight intravenously had no significant effect on either thermal or emotional sweating, whereas thermal sweating was completely blocked temporarily by administration of atropine 2.4 mg intravenously.4. It is concluded that beta-adrenoceptor blockade has no effect on physiological sweating in normal people. PMID- 4147189 TI - On the mechanism of L-dopa-induced postural hypotension in the cat. AB - 1. The effects of L-DOPA on postural hypotension and carotid occlusion pressor effect were studied, mainly in cats; the recovery of the blood pressure upon tilting was used as a measure of postural hypotension.2. L-DOPA (30 mg/kg) partially depressed the carotid occlusion pressor effect and caused some degree of postural hypotension, L-DOPA (100 mg/kg) had more marked effects; the responses returned to control after 90 to 150 minutes. L-DOPA itself caused a pressor response in all cats.3. The dopa decarboxylase inhibitor N(1)-(DL-seryl) N(2)-(2,3,4-trihydroxybenzyl) hydrazine (RO4-4602, 50 and 10 mg/kg) had no effect itself on the tilt response but completely prevented the effects of L-DOPA on the carotid occlusion pressor effect and postural hypotension.4. After RO4-4602 (3 and 1 mg/kg), L-DOPA (100 mg/kg) caused a brief rise of blood pressure followed by a longer lasting fall in horizontally-orientated cats (i.e. ;supine' hypotension). No postural hypotension was observed after L-DOPA under these conditions.5. Noradrenaline elicited only small and transient effects on postural hypotension, but dopamine's effects were more marked and longer lasting. Pressor dose-response relationships for noradrenaline were the same before and after L DOPA, as well as in cats pretreated with L-DOPA for 4 days.6. In cats with kidneys and intestines removed, the tilt reflex was still present. Dose-response curves to L-DOPA were the same as in normal animals. RO4-4602 (3 mg/kg) prevented postural hypotension and block of the carotid occlusion pressor effect; supine hypotension was also observed after L-DOPA.7. The recovery response to tilting in spinal cats was markedly depressed or absent unless the blood pressure was elevated by angiotensin, in which experiments L-DOPA depressed the recovery upon tilting (i.e. induced postural hypotension).8. Blood pressure responses to tyramine were increased after 10 mg/kg of L-DOPA, but depressed after 100 mg/kg. The response to tyramine was not depressed, however, when RO4-4602 was given to block the dopa-dopamine conversion.9. The response to sympathetic stimulation in pithed rats was depressed after L-DOPA and dopamine, but not after alpha methyldopa.10. alpha-Methyldopa (300 mg/kg) given acutely caused a moderate degree of postural hypotension and a more marked postural hypotension if given for two days.11. It is concluded that it is possible to differentiate between the supine and postural hypotension caused by L-DOPA and that supine hypotension is due to a central effect and postural hypotension to an extracerebral effect. Postural hypotension is discussed in relation to six hypotheses presented to explain its effect. Postural hypotension after L-DOPA is probably not due to a adrenoceptor blockade, a central effect or any effect on the kidney. The most likely hypothesis is that L-DOPA forms dopamine which acts as a false transmitter in the peripheral sympathetic nervous system. PMID- 4147191 TI - Acute systemic anaphylaxis in the calf. AB - 1. Acute systemic anaphylaxis in calves was characterized by marked systemic hypotension; hypertension in the pulmonary arteries and abdominal vena cava, and transient apnoea. Calves responded with a second reaction to antigen, but a third anaphylactic response could not be evoked.2. Suppression of systemic anaphylaxis could not be effected with mepyramine, whereas methysergide or diethylcarbamazine each suppressed anaphylaxis by 50%. Disodium cromoglycate alone did not inhibit anaphylaxis: however, when disodium cromoglycate was combined with diethylcarbamazine almost total suppression (85%) was achieved. Sodium meclofenamate also was a powerful inhibitor of anaphylaxis (80%). It is tentatively suggested that slow reacting substance (SRS-A) may be an important mediator of bovine anaphylaxis.3. Bilateral vagotomy did not modify the circulatory responses to injected histamine, 5-hydroxytryptamine (5-HT) or antigen, whereas the effects of these agents on ventilation (apnoea) were abolished by vagotomy.4. Plasma histamine concentration was increased during anaphylaxis, whereas plasma 5-HT was not. Whole blood histamine concentration fell sharply and remained depressed during 20 min of anaphylactic shock. Reduced whole blood histamine levels probably reflect the severe leucopoenia in the calves.5. Histamine concentrations in six tissues taken from calves subjected to anaphylaxis were not different from those in control calves; mast cells were of similar numbers to controls, but showed some swelling, granular spilling and metachromasia.6. Histamine, 5-HT, bradykinin and antigen caused increased pulmonary artery perfusion pressure and ventilation resistance in isolated lungs from sensitized calves. However, there was no difference in histamine and 5-HT concentration in perfusates obtained during antigen infusion of sensitized and control lungs.7. Systemic anaphylaxis of calves may result from the interaction of histamine, 5-HT and SRS-A. The present data implicate (by indirect measurement) SRS-A as an important mediator of anaphylaxis in this species. PMID- 4147192 TI - Pharmacokinetics of M&B 17,803A in animals and man. PMID- 4147193 TI - Isoprenaline antagonism and duration of action in exercise induced tachycardia of three -adrenoceptor blocking drugs: pindolol, LF 17-895 and propranolol. PMID- 4147194 TI - Induction of liver microsomal drug metabolism in newly-hatched chicks. PMID- 4147195 TI - Cardiovascular and respiratory effects of cannabis extracts and 1-tetra hydrocannabinol ( 1-THC). PMID- 4147196 TI - The occurrence of tryptamine in rat brain and its pharmacological manipulation. PMID- 4147197 TI - The effect of AH 5158, pindolol, propranolol, D-propranolol on acute exercise tolerance in angina pectoris. PMID- 4147198 TI - The -adrenoceptor blocking activity of desacetylthymoxamine on human isolated smooth muscle. PMID- 4147199 TI - The buccal absorption of some -adrenoceptor blocking drugs. PMID- 4147200 TI - Isolation of St. Louis encephalitis and Cache Valley viruses from Saskatchewan mosquitoes. PMID- 4147201 TI - A comparative study of pig and sheep-brain glutamine synthetases: tryptic peptides and thiol groups. PMID- 4147202 TI - Studies of glutamate dehydrogenase. The influence of ADP, GTP, and L-glutamate on the binding of the reduced coenzyme to beef-liver glutamate dehydrogenase. PMID- 4147203 TI - Properties of a yeast cytochrome P-450-containing enzyme system which catalyzes the hydroxylation of fatty acids, alkanes, and drugs. PMID- 4147204 TI - [Psychological reasons for the failure in pulmonary tuberculosis treatment]. PMID- 4147205 TI - An outbreak of dengue-type fever among royal marines in Sabah--1964. PMID- 4147206 TI - [Comparative biochemistry of uric acid synthesizing enzymes]. PMID- 4147207 TI - [Autopsy case of periarteritis nodosa in a child]. PMID- 4147208 TI - [Current topics on cerebral amines: with special reference to the topics at the symposium at the annual meeting of Endocrinology Society]. PMID- 4147210 TI - [Post-exercise bronchospasm in patients with asthma and attempts at its prevention with antihistaminic agents]. PMID- 4147209 TI - Evidence for participation of a catecholaminergic mechanism in the post castration rise in plasma gonadotropins. PMID- 4147211 TI - Systemic corticosteroid therapy in rheumatic diseases. PMID- 4147212 TI - Angina pectoris. PMID- 4147213 TI - Clinical assessment of bronchodilator drugs delivered by aerosol. PMID- 4147214 TI - [Use of beta-blockaders in the treatment of arrhythmias associated with acute myocardial infarct]. PMID- 4147215 TI - Stereochemistry of reduction of D-glyceraldehyde catalyzed by a nicotinamide adenine dinucleotide phosphate dependent dehydrogenase from skeletal muscle. PMID- 4147216 TI - Interactions of reduced and oxidized triphosphopyridine nucleotides with the electron-transport system of bovine heart mitochondria. PMID- 4147218 TI - [Effect of the study load on the functional state of the central nervous system in students at schools for children with speech disorders]. PMID- 4147217 TI - Regional distribution of some enzymes involved with putative neurotransmitters in the human visual system. PMID- 4147219 TI - Time and level of increased plasma corticosterone necessary for induction of liver tyrosine aminotransferase in rats subjected to trauma. PMID- 4147220 TI - Drugs in cardiogenic shock. PMID- 4147221 TI - [Drug therapy in cardiogenic shock]. PMID- 4147222 TI - [Clinical management of cardiogenic shock]. PMID- 4147223 TI - Assay of ipecac and its preparations. I. Development of the method. PMID- 4147224 TI - Assay of ipecac and its preparations. II. Collaborative study. PMID- 4147225 TI - Identification of phenothiazine derivatives and analogs by x-ray diffraction. I. Examination of pure compounds. PMID- 4147226 TI - Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations. PMID- 4147227 TI - [Symposium: improvement of curability rate in lung cancer by early diagnosis and prevention of postoperative metastasis]. PMID- 4147228 TI - [Establishment of functional criteria in surgery of lung cancer to improve surgical curability and standardization of postoperative care for the prevention of pulmonary complicactions]. PMID- 4147229 TI - [Improvement of surgical curability in lung cancer]. PMID- 4147230 TI - [Improvement of surgical curability in lung cancer]. PMID- 4147231 TI - [Radiotherapy of lung cancer]. PMID- 4147232 TI - [Pathological consideration on combined therapy of lung cancer]. PMID- 4147233 TI - [Transposition of great vessels]. PMID- 4147234 TI - [Endocardial cushion defect]. PMID- 4147235 TI - [Radical surgery of tetralogy of Fallot]. PMID- 4147236 TI - [Prosthetic valve replacement]. PMID- 4147237 TI - [Some special surgical methods for difficult cardiac operation]. PMID- 4147238 TI - [Keypoints in difficult cardiac operation]. PMID- 4147240 TI - [Studies on diazabicycloalkanes. II. Antihistaminic and psychotropic activities of 4-(beta-(10-phenothiazinyl)-ethyl)-1,4-diazabicyclo (4,4,0)-decane and its related compounds]. PMID- 4147239 TI - Non-otogenic cerebral abscess. AB - Non-otogenic cerebral abscess is becoming relatively more frequent compared with otogenic. It arises in a setting of sepsis, trauma, or congenital heart disease. The onset presents a meningo-encephalitic picture, often with two stages, followed by epilepsy and/or a hemiparesis. The best investigations are an EEG and, probably, an isotope scan. The angiogram may be misleading as 40% may not have a midline shift. 'Acute localized non-suppurative encephalitis' seems to be more frequent than in the past. Antibiotics and aspiration appear to be the best treatment. PMID- 4147241 TI - Oxidation of NADH in a coupled oxidase-peroxidase reaction and its significance for the fermentation in rumen protozoa of the genus Isotricha. PMID- 4147242 TI - [Hemodynamic effects of a new beta-adrenergic blocking agent]. PMID- 4147243 TI - Mutations affecting levels of tetrahydrofolate interconversion enzymes in Saccharomyces cerevisiae. I. Enzyme levels in ade3-41 and ADE15, a dominant adenine auxotroph. PMID- 4147244 TI - Mutations affecting levels of tetrahydrofolate interconversion enzymes in Saccharomyces cerevisiae. II. Map positions on chromosome VII of ade3-41 and ADE15. PMID- 4147245 TI - Implanted-pacemaker-induced dysrhythmia and its management. PMID- 4147246 TI - Comparison of propranolol and Ro 3-3528 in hyperthyroid tachycardia and dysrhythmias. PMID- 4147247 TI - [Basis for the use of beta-receptor blockaders in the practice]. PMID- 4147248 TI - [Beta-receptor blockaders and angina pectoris]. PMID- 4147249 TI - [Beta blockaders and arrhythmias]. PMID- 4147250 TI - [Side effects, contraindications and antagonistic measures in the use of beta receptor blockaders]. PMID- 4147251 TI - [Beta-receptor blockaders in general practice]. PMID- 4147252 TI - [Slow-reacting substances. Bibliographical review]. PMID- 4147253 TI - Effect of monolayer fractionation of lymphocytes on graft-versus-host reactivity. PMID- 4147254 TI - [Current problems of psychopharmacology]. PMID- 4147255 TI - [Problems of psychopharmacologic therapy]. PMID- 4147256 TI - [Homoeoplastic skin transplantation after chemical sterilization and preservation. 1. Method-bacteriological, histological and histochemical studies. 2. Clinical testing and evaluation]. PMID- 4147258 TI - [Treatment of gastric dyspepsia using Medrin and its comparison with metoclopramide (Primperan) therapy]. PMID- 4147259 TI - The effect of antihistamines on the suppression of skin tests. PMID- 4147261 TI - Surgery and anticoagulation therapy. PMID- 4147262 TI - Case report: celiac artery aneurysm. PMID- 4147264 TI - Continuing medical education and professional growth--"the physician's protection". PMID- 4147263 TI - Illinois Emergency Medical Service System. Status report II (July, 1973). PMID- 4147265 TI - Febrile reaction of Gaucher's disease. PMID- 4147266 TI - Gunshot wound of the back. PMID- 4147267 TI - Selecting medical students. PMID- 4147268 TI - Herman von Helmholtz, 1821-1894 physician, musician and versatile scientist. PMID- 4147269 TI - The viewbox: gallstone obstruction of the colon. PMID- 4147270 TI - EKG of the month: Myocardial infarct and arrhythmia. PMID- 4147271 TI - Beta blockade. PMID- 4147272 TI - The pharmacological characterization of beta-sympathicolytic substances. PMID- 4147273 TI - On the importance of a central beta-adrenoceptor site in the antiarrhythmic activity of beta-blockers. PMID- 4147274 TI - A preliminary report on the duration of beta-blockade after oral intake of L-B46. PMID- 4147275 TI - LB-46 in angina pectoris. A critique of anti-anginal drug assessment. PMID- 4147276 TI - Anti-arrhythmic effects of LB-46 on experimentally produced digitoxic arrhythmias. PMID- 4147277 TI - Side-effects of beta-adrenergic blocking drugs in asthmatics. PMID- 4147278 TI - The hypotensive action of LB 46. PMID- 4147279 TI - The effect of LB 46 on the blood pressure in essential hypertension. PMID- 4147280 TI - Treatment of psycho-neurotic conversion reactions with pindolol. (Effect on cardio-vascular response to exercise). PMID- 4147281 TI - [Fatigue fractures in recruits during basic training]. PMID- 4147282 TI - [Compensating mechanism in cardiac insufficiency and therapeutic-preventive principles]. PMID- 4147283 TI - [The effect of various neurotropic drugs on the mechanism of regulating complex rhythmic stereotypes]. PMID- 4147284 TI - Dechlorination of chloroethane with a reconstituted liver microsomal system. PMID- 4147285 TI - Calf thymus GMP reductase: control by XMP. PMID- 4147286 TI - The second messenger system of mouse epidermis. 3. Guanyl cyclase. PMID- 4147287 TI - Heme-modification studies of myoglobin. II. Ligand binding characteristics of ferric and ferrous myoglobins containing unnatural hemes. PMID- 4147289 TI - Antinuclear antibodies in hybrid mice inoculated with parental spleen cells. PMID- 4147288 TI - Determination of gamma glutamyl transpeptidase activity in human serum. Its use in oncology. PMID- 4147290 TI - In vitro and in vivo metabolism of 3-trifluoromethyl-4-nitrophenol (TFM) in rainbow trout. PMID- 4147291 TI - [Activity of gamma-GT (gamma-glutamyltranspeptidase) in bovine serum]. PMID- 4147292 TI - Vaccination against schistosomes? Report of an expert conference sponsored by the Rockefeller Foundation. PMID- 4147293 TI - The level of questions posed by nursing educators. PMID- 4147294 TI - Utilizing questioning strategies in nursing education. PMID- 4147295 TI - The nursing student: social background, attitudes, and expressed willingness to work in poverty programs. PMID- 4147296 TI - Criteria for choosing textbooks for the nontraditional professional nursing curriculum. PMID- 4147297 TI - Attitudes of cynicism and humanitarianism in nursing students and staff nurses. PMID- 4147298 TI - Hyperpyrexia from drug combinations. PMID- 4147300 TI - Isozymic heterogeneity in Tetrahymena strains. AB - Examination of electrophoretic mobility patterns indicates that the strain designations of 44 classical strains of Tetrahymena are confused. It is suggested that new designations be made on the basis of phenotypic similarity. PMID- 4147301 TI - [Evaluation of aptine, a new adrenergic beta blockader, in angina pectoris]. PMID- 4147302 TI - [A cardio-selective beta blockader: practolol]. PMID- 4147303 TI - [Rheumatoid arthritis. Pathogenic mechanisms and therapeutic consequences]. PMID- 4147304 TI - [Nasal obstruction in children]. PMID- 4147305 TI - [Microbial flora in dacryocystitis]. PMID- 4147306 TI - Current therapy of shock. PMID- 4147307 TI - Cell-mediated immunity. PMID- 4147308 TI - The past four decades of progress in the knowledge of gout, with an assessment of the present status. PMID- 4147309 TI - [Effect of stimulation of adrenergic bronchial beta receptors by terbutalin on the bronchomotoric effects of propranolol and acetylcholine]. PMID- 4147310 TI - [Effect of trimepranol on somatotropin, insulin, glucose and nonesterified fatty acid levels in man]. PMID- 4147311 TI - Drug treatment of hyperactivity in children. PMID- 4147312 TI - Confusing urinary bladder defects and configurations. PMID- 4147313 TI - "The way to a man's heart attack". PMID- 4147314 TI - Multiloculated cystadenoma of the liver. PMID- 4147315 TI - Gas infection of thigh. PMID- 4147316 TI - Repeated bouts of pneumonitis cough with feedings and abdominal distention. PMID- 4147317 TI - A statewide system for post-traumatic renal failure. PMID- 4147318 TI - A heroin addiction scale revisited. PMID- 4147319 TI - [The effect of vibration on corticosterone and nicotinamide-adenine-dinucleotide phosphate level in the rat adrenal and serum]. PMID- 4147320 TI - [Diagnostic significance of denture findings and the schema of the International Dental Federation (I.D.F.)]. PMID- 4147321 TI - [Suppurative osteomyelitis of the pedal bone in a thoroughbred horse]. PMID- 4147322 TI - Malignant lymphoma and amyloidosis following graft-versus-host reaction. PMID- 4147323 TI - Studies on inflammation in the sheep, using turpentine-induced pleurisy as a test system. 2. Suppression of the increased vascular permeability by specific antagonists of chemical mediators, anti-inflammatory agents and other substances. PMID- 4147324 TI - [Treatment of acute intermittent porphyria]. PMID- 4147326 TI - Membrane effects of beta-adrenergic blocking agents: investigations with the fluorescence probe 1-anilino-8-naphthalene sulfonate (ANS) and antihemolytic activities. PMID- 4147327 TI - Effect of excess and deficient copper intake on rat liver microsomal enzyme activity. PMID- 4147328 TI - Effect of olivomycin on the induced synthesis of tyrosine aminotransferase and tryptophan oxygenase in rat liver. PMID- 4147329 TI - Effect of chronic feeding on the activities and submicrosomal distribution of reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase and the demethylases for aminopyrine and ethylmorphine. PMID- 4147330 TI - Prostaglandin-versus alpha-adrenoceptor-mediated control of sympathetic neurotransmitter secretion in guinea-pig isolated vas deferens. PMID- 4147331 TI - The model of functional interaction. I. Development and first check of a new model of functional synergism and antagonism. PMID- 4147332 TI - The model of functional interaction. II. Experimental verification of a new model: the antagonism of beta-adrenoceptor stimulants and other agonists. PMID- 4147333 TI - Modulating effect of central adrenergic neurones on a vagally mediated cardioinhibitory reflex. PMID- 4147334 TI - A further attempt to characterize sedative receptors activated by clonidine in chickens and mice. PMID- 4147335 TI - Thymic involution and ageing. PMID- 4147336 TI - [Salbutamol in chronic bronchial asthma]. PMID- 4147337 TI - Rabies prophylaxis--a primer. PMID- 4147338 TI - Studies of histoplasmosis in two Illinois communities. PMID- 4147339 TI - Accidental ingestion. PMID- 4147340 TI - Nonketotic hyperglycemic coma in infancy. PMID- 4147341 TI - Ulcer recurrence after vagotomy and pyloroplasty. PMID- 4147342 TI - Delayed ovulation. PMID- 4147343 TI - Traumatic rupture of thoracic aorta. PMID- 4147344 TI - The use and abuse of antibiotic and chemotherapeutic remedies. PMID- 4147345 TI - The story of rheumatology in Chicago. PMID- 4147346 TI - Disability insurance under social security. PMID- 4147348 TI - Vector control in Arkansas. PMID- 4147347 TI - The aminoterminal sequence of antibody light chains: evidence for possible inheritance of structural genes. PMID- 4147349 TI - Insect developmental inhibitors. 2. Effects on target mosquito species. PMID- 4147350 TI - Protective effect of cyproheptadine and BC 105 against the lethal effects of exudates from rat burnt skin. PMID- 4147351 TI - Cardiology for the practitioner. II. The medical management of angina pectoris. PMID- 4147352 TI - [Treatment of acute pancreatitis]. PMID- 4147353 TI - [Life expectancy of alcoholics]. PMID- 4147354 TI - [Insurance-medical expert testimony on schizophrenia]. PMID- 4147355 TI - [Prognosis of hemophilia]. PMID- 4147356 TI - [Glomerulonephritis]. PMID- 4147358 TI - [Union of precious and non-precious metal alloys with attachments for porcelain]. PMID- 4147357 TI - Treatment of hemorrhagic shock with a new vasodilator. PMID- 4147359 TI - [Lung manifestations in connectivitis]. PMID- 4147360 TI - [Complications of vaccinations]. PMID- 4147361 TI - [Blood urokaninase and histidase activity in pregnancy complicated by toxicosis]. PMID- 4147362 TI - Neuroendocrine aspects of thermoregulation. PMID- 4147363 TI - Leukocyte adenyl cyclase and ATPase in asthma: effect of corticosteroid therapy. PMID- 4147364 TI - Rapidity of response to the treatment of enuresis. PMID- 4147365 TI - The specificity of yeast fatty-acid synthetase with respect to the "priming" substrate. Decanoyl-coA and derivatives as "primers" of fatty-acid synthesis in vitro. PMID- 4147366 TI - Omega-hydroxylation of steriod side-chain in biosynthesis of bile acids. PMID- 4147368 TI - [Experience in the work of medical feldshers in hospitals of the region]. PMID- 4147367 TI - Reduction of C19-, C21-, C24-, and C27-3-oxosteroids by rat-liver microsomes. PMID- 4147370 TI - A study of the dental caries status of the preschool children among the play centers of health district I and II, Manila Health Center. PMID- 4147369 TI - [Protective reactions of the body and heredity]. PMID- 4147371 TI - [Experience with Vadilex in the treatment of cerebral vascular insufficiency]. PMID- 4147372 TI - Evaluation of clinical and antibacterial activity of pyrrolidinemethyltetracycline. PMID- 4147373 TI - [Imminent abortion]. PMID- 4147374 TI - Activation of the central pathway of the baroreceptor reflex, a possible mechanism of the hypotensive action of clonidine. PMID- 4147376 TI - Teething, diet and health. 6. PMID- 4147375 TI - Antifibrillatory effect of beta-adrenergic agonists. PMID- 4147377 TI - Ethanol metabolism in the liver. PMID- 4147378 TI - The treatment of atopic dermatitis. PMID- 4147379 TI - [Dynamics and treatment of the tendency to enchronization of schizophrenic psychoses]. PMID- 4147380 TI - Immunologic reconstitution. PMID- 4147381 TI - Stereoisomerism and drug action in the nervous system. PMID- 4147382 TI - Resolution of optical isomers of 5-allyl-5-(beta-hydroxypropyl)-barbituric acid (Ipronal, Axeen) and their pharmacological activity. PMID- 4147383 TI - Cocaine and catecholamine interaction. A review. PMID- 4147384 TI - Metabolism of volatile anaesthetics. PMID- 4147385 TI - Undescended testicle. PMID- 4147386 TI - Antimetabolites of coenzyme Q. 14. Quinolinequinone analogs which inhibit mitochondrial DPNH-oxidase and succinoxidase. PMID- 4147387 TI - Conformation effects on the activity of drugs. 4. Cyclic analogs of 1-(p nitrophenyl)-2-isopropylaminoethanol. Synthesis and evaluation of the adrenergic beta-receptor blocking activity of 2-(p-nitrophenyl)-4-isopropylmorpholine. PMID- 4147388 TI - Derivatives of 3,4-dihydro-1(2H)-naphthalenone as beta-adrenergic blocking agents. 2. Aromatic-substituted analogs of bunolol. PMID- 4147389 TI - Electron impact fragmentation studies of beta-blocking drugs and their metabolites by GC-mass spectroscopy. PMID- 4147390 TI - [Josamycin propionate. 3. Pharmacological studies]. PMID- 4147391 TI - Immunosuppression and neoplasia. I. A critical review of experimental carcinogenesis and the immunesurveillance theory. PMID- 4147392 TI - [Impuberism and hypogonadism at induction into military service. Statistical study]. PMID- 4147393 TI - [The pharmacology of antihypertensive agents]. PMID- 4147394 TI - [The treatment of arterial hypertension associated with renal insufficiency]. PMID- 4147395 TI - [Labile hypertension]. PMID- 4147396 TI - [Clinical use of cypenam and a technique of individual dose treatment of patients with nonspecific diseases of the lungs and pulmonary heart disease]. PMID- 4147398 TI - [Statistical evaluation of allergic reactions following vaccinations against foot and-mouth disease in 1970]. PMID- 4147397 TI - [Isolation of vaccina virus from dermovaccine. A comparative study of modern preparative methods for vaccine production. I. Column chromatography on agarose gels and controlled pore glass (CP-glass)]. PMID- 4147400 TI - [Studies on the DNase-production of clostridia]. PMID- 4147399 TI - [The action of proteolytic enzymes of Clostridium histolyticum and Clostridium novyi on human plasma proteins]. PMID- 4147401 TI - [Peach and peach juice as a nutrient substratum for Cryptococcus neoformans with comments on some observations of F. Sanfelice (1894)]. PMID- 4147402 TI - [Skin tests with Schistosoma mansoni antigen in cases of swimmers' itch]. PMID- 4147403 TI - [Comparative studies by the electron microscope of rhabdoviruses of plant and of animal origin. II. Investigations by electron microscopy and by cytological methods of the host plant Sonchus oleraceus (L.) and the vector hyperomyzus lactucae (L.) after infection with the Sowthistle Yellow Vein Virus (SYVV)]. PMID- 4147404 TI - [Hepatitis-associated antigen: purification and properties]. PMID- 4147405 TI - A rapid embedding technique for electron microscopic study of a bovine herpesvirus. PMID- 4147406 TI - The relationship between antagonistic properties and serologic type in staphylococci of bacteriophage group II. PMID- 4147407 TI - [RK test--its use for diagnosis of streptococci of group B]. PMID- 4147408 TI - [Studies on the determination of nalidixic acid-resistance of R-plasmids in E. coli]. PMID- 4147409 TI - [Cellular immune response in spleen and intestine as demonstrated by the model of direct agar plaque technique subsequent to parenteral and oral immunization of mice with heat-inactivated s. typhi murium antigen]. PMID- 4147410 TI - Treatment of the cardiomyopathies. PMID- 4147411 TI - Islet cell tumors: current concepts and management. PMID- 4147412 TI - [Allogenic cornea transplantation in inbred rats. II. Effect of sensitizations]. PMID- 4147413 TI - The purification of nicotinamide nucleotide-dependent dehydrogenases on immobilized cofactors. AB - 1. The general applicability of affinity chromatography to the purification of nicotinamide nucleotide-dependent dehydrogenases on immobilized cofactors is illustrated with several examples taken from crude systems. 2. Methods for overcoming the inevitable loss of selectivity experienced with these polymers are suggested. Effective use of the appropriate nucleotide, the second substrate and other interacting ligands can be made to selectively alter the chromatographic behaviour of the desired enzyme. PMID- 4147414 TI - The sick sinus syndrome. PMID- 4147416 TI - [Oncology: introduction]. PMID- 4147415 TI - Duration of action of beta-blocking drugs. PMID- 4147418 TI - [Enzyme activity of human milk in relation to amino acid arylamides]. PMID- 4147419 TI - CCl4-induced damage to endoplasmatic reticulum membranes. PMID- 4147420 TI - Studies on the interaction between catecholamines and tyrosine aminotransferase in brain. PMID- 4147421 TI - On the convulsive action of castrix. PMID- 4147422 TI - Decarboxylase inhibition and structure-activity relationship studies with some newly synthetized benzyloxyamine and pyridylmethoxyamine derivatives. PMID- 4147423 TI - The NAD-linked isocitrate dehydrogenase activity in rat-liver mitochondria. PMID- 4147424 TI - On the oxidation of reduced nicotinamide dinucleotide phosphate by submitochondrial particles from beef heart. PMID- 4147425 TI - Marijuana smoking: effects on blood and urine in man. PMID- 4147426 TI - The effects on cardiac muscle and nerve of a fluorinated decahydroquinoline derivative, L7810, rapidly absorbed after oral administration. AB - 1. L7810 (4-carbamoyloxy-1-(4-(4-fluorophenyl)-4-oxobutyl) decahydroquinoline, has a local anaesthetic action on frog nerve 1.75 times that of procaine.2. L7810 protected anaesthetized guinea-pigs against ouabain-induced ventricular fibrillation and increased the lethal dose of ouabain.3. L7810 reduced the rate of rise of intracellularly recorded action potentials in rabbit isolated atria; the resting potential was not affected, but the duration of the action potential was prolonged.4. Unlike most drugs with local anaesthetic properties L7810 did not depress contractions in isolated atria but increased them.5. L7810 reduced the spontaneous frequency, maximum follow frequency and conduction velocity of rabbit isolated atria.6. L7810 had no blocking action on the chronotropic or positive inotropic actions of isoprenaline on isolated atrial muscle.7. In anaesthetized dogs L7810 caused a small dose-related bradycardia, and a large dose-related decrease in peripheral vascular resistance. There was no blockade of the effects of isoprenaline on heart rate or peripheral blood flow. PMID- 4147427 TI - Beta-adrenoceptor blocking properties and cardioselectivity of M & B 17,803A. AB - 1. The beta-adrenoceptor blocking properties of (+/-)-1-(2-acetyl-4-n butyramidophenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride (M&B 17,803A) have been compared with those of practolol and propranolol in the guinea-pig, cat and dog.2. Following either intravenous or oral administration in the cat or dog, M&B 17,803A and practolol had similar potency in antagonizing isoprenaline induced tachycardia and both showed cardioselectivity, but both were less potent than propranolol.3. M&B 17,803A and practolol had approximately one hundredth the intravenous potency of propranolol in increasing the severity of anaphylactic bronchospasm in the conscious sensitized guinea-pig.4. M&B 17,803A possessed less marked intrinsic sympathomimetic activity than practolol but, like propranolol, it had significant local anaesthetic properties and increased the refractory period of rabbit isolated atria. PMID- 4147428 TI - A new type of cardioselective adrenoceptive blocking drug. PMID- 4147429 TI - The action of ICI-66082 on the heart. PMID- 4147430 TI - The blocking effects of propranolol, practolol and ICI-66082 on the peripheral vascular responses to isoprenaline. PMID- 4147431 TI - Effect of intraperitoneal administration of (+)-INPEA on oxytocin and prostaglandin evoked responses of the isolated rat uterus. PMID- 4147432 TI - Evidence of a role for brain monoamines in ethanol dependence. PMID- 4147433 TI - Application of the dansyl technique to an investigation into the identity of the primary sensory transmitter in the spinal cord. PMID- 4147434 TI - Electrically induced contractions of guinea-pig isolated ileum resistant to tetrodotoxin. PMID- 4147435 TI - Evidence for a non-adrenergic inhibitory nervous pathway in guinea-pig trachea. PMID- 4147436 TI - Antagonism by burimamide of inhibitions induced by histamine in plexus-containing longitudinal muscle preparations from guinea-pig ileum. PMID- 4147437 TI - A study of the role of catecholamines in the response to various central stimulants. PMID- 4147438 TI - Actions of beta-blocking agents on membrane excitability of the lobster giant axon. PMID- 4147439 TI - Continued pharmacologic analysis of consummatory behavior in the albino rat. PMID- 4147440 TI - Further studies on the site of action of nicotinic blocking drugs. PMID- 4147441 TI - [Precipitation reactions for dicoline]. PMID- 4147442 TI - Ammonium repression in a mutant of Saccharomyces carlsbergensis lacking NADP dependent glutamate dehydrogenase activity. PMID- 4147443 TI - [Early therapy of light hypertension]. PMID- 4147444 TI - Electrochemical redox pattern for nicotinamide species in nonaqueous media. PMID- 4147445 TI - Carbon-13 magnetic resonance spectroscopy and the biosynthesis of streptovaricin. PMID- 4147446 TI - Evaluation of liquid-liquid systems for the chromatographic separation of the psychotropic thioridazine and it's metabolites. PMID- 4147448 TI - [Diabetes mellitus in periarteritis nodosa]. PMID- 4147447 TI - [Polarographic analysis of bromoisovalerylurea (bromural) and bromodiethylacetylcarbamide (carbromal) in mixtures and complex combinations]. PMID- 4147449 TI - [Addiction-like provocation of psychomotor seizures by daydreams]. PMID- 4147450 TI - Enzyme assay in microsomes below zero degrees. AB - Reactions of a membrane-bound multienzyme complex (electron-transport chain of rat-liver microsomes) suspended in aqueous-organic solvent used as antifreeze at temperatures below 0 degrees were studied. In the presence of a relatively high concentration of ethylene glycol, electron transfer can still be observed and some individual and sequential enzyme assays can be performed over a wide range of temperatures below 0 degrees . PMID- 4147451 TI - Changing concepts of hepatitis B infection. PMID- 4147452 TI - The reduction of certain C-nitroso compounds by rat liver cytosol. PMID- 4147453 TI - [Electron microscopic picture of collagen in correlation to chemical composition seen in the sea anemone (Metridium dianthus)]. PMID- 4147454 TI - Oxidation of reduced nicotinamide hypoxanthine dinucleotide phosphate by intact rat liver mitochondria. PMID- 4147455 TI - NADH(NADPH): (acceptor) oxidoreductase activities of the bovine adrenal chromaffin granules. PMID- 4147456 TI - The function and localization of ubiquinone in the NADH and succinate oxidase systems of Rhodopseudomonas palustris. PMID- 4147457 TI - Function of reduced pyridine nucleotide-ferredoxin oxidoreductases in saccharolytic Clostridia. PMID- 4147458 TI - Fractionation by sucrose density gradient centrifugation of membrane fragments derived by sonic disruption of beef heart mitochondria. PMID- 4147459 TI - [Treatment of vascular headaches]. PMID- 4147460 TI - [Serum gamma-glutamyl transpeptidase, glutamate-pyruvate transaminase and HAA antibody determinations in the selection of blood donors]. PMID- 4147461 TI - [Cardiac toxicity of antidepressive agents]. PMID- 4147462 TI - [Acanthosis nigricans in liver hamartoma and excessive increase of serum gallic acids: a hitherto undescribed combination]. PMID- 4147464 TI - Cross-reactions of additional extracellular polysaccharides of Klebsiella. PMID- 4147463 TI - The responsiveness of tolerant lymphocyte populations after transfer to normal recipients. PMID- 4147465 TI - Graft-vs-host reaction with an H-2 mutant. PMID- 4147466 TI - Xenogeneic reactivity of human fetal lymphocytes. PMID- 4147467 TI - Histochemical studies on the Leydig-cell-leucine aminopeptidase activity in the guinea-pig testis. PMID- 4147468 TI - [Gamma-glutamyl transpeptidase--interpretation of the test results]. PMID- 4147469 TI - [Acetyl-CoA carboxylase--multienzyme (author's transl)]. PMID- 4147470 TI - [Control mechanism of globin synthesis by hemin--formation of hemin controlled repressor and its mode of action (author's transl)]. PMID- 4147471 TI - Neurological complications of the rheumatic diseases. PMID- 4147472 TI - Accumulation of 125I-labelled albumin as a measure of the inflammatory response in experimental arthritis. PMID- 4147473 TI - Studies on new sympathomimetic beta-receptor stimulating drugs in asthmatic patients. I. The bronchodilator and circulatory effects of subcutaneous terbutaline. PMID- 4147474 TI - Action of prostaglandin E-1 (PGE-1) on human pregnant (at the time of labor) and non-pregnant uterus in vivo and modification of this action by adrenergic receptor blocking agents. PMID- 4147475 TI - An anatomy of schizophrenia? PMID- 4147476 TI - Acyl coenzyme A inhibition of Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase: a comparison of the TPN and DPN linked reactions. PMID- 4147477 TI - NADPH-D-glyceraldehyde 3-phosphate oxidoreductase activity in muscle and other tissues of the rat. PMID- 4147478 TI - Similarities in the bioluminescence from the Pennatulacea. PMID- 4147479 TI - Cross-reactions of polysaccharides of Lipomyces in antipneumoccal and other antisera. PMID- 4147480 TI - [The amplitude of acoustically evoked potentials during different stimulus load and decrease of vigilance]. PMID- 4147481 TI - Patterns of cytochrome oxidase inhibition by polycations. PMID- 4147482 TI - Studies on the function of cell membrane. l. Leakage of NADH-cytochrome c reductase into plasma from liver cells in CC4-poisoned rats. PMID- 4147483 TI - Involvement of adrenergic mechanism in the diuretic action of o-chlorobenzyl methyl sulfoxide (DS-30) in the rat. PMID- 4147484 TI - Antisympathomimetic effects of Ko 1313 and Ko 1366 in guinea-pig atria. PMID- 4147485 TI - Bacterial attack on phenolic ethers. Dealkylation of higher ethers and further observations on O-demethylases. PMID- 4147486 TI - Irreversible protein binding of metabolites of ethynylestradiol in vivo and in vitro. PMID- 4147487 TI - Steroid metabolism by mouse submaxillary glands. I. In vitro metabolism of testosterone and 4-androstene-3,17-dione. PMID- 4147488 TI - Experimental allergic sialoadenitis. VI. Prevention by antihistamine and induction by intraductal instillation of performed immune complexes. PMID- 4147490 TI - [Effect of beta receptor blockaders on pulse wave velocity. Studies of the new beta bockader Ko 1366]. PMID- 4147489 TI - [Adrenergic and cholinergic mechanisms in the development of a balneological reaction and an exacerbation reaction during the mud therapy of children with chronic tonsillitis]. PMID- 4147491 TI - [Lymphoreticular sarcomas in immuno-defect mice]. PMID- 4147492 TI - [Pharmacologic modification of human myometrium activity in in-vitro studies. V. Effect of Th 1165 a on isolated myometrium strips]. PMID- 4147493 TI - [Use of the new neuroleptic drug leptril in psychiatric practice]. PMID- 4147494 TI - Tetracycline-resistant pneumococci: increasing incidence and cross resistance to newer tetracyclines. PMID- 4147495 TI - Acetyl-CoA and propionyl-CoA carboxylation by Mycobacterium phlei. Partial purification and some properties of the enzyme. PMID- 4147496 TI - The stimulatory effect of tumor bearing upon the T- and B-cell subpopulations of the mouse spleen. PMID- 4147497 TI - Tritiated leucine incorporation by Sertoli cells in scrotal and cryptorchid rat testes. PMID- 4147498 TI - Genetic and epidemiologic studies of oral characteristics in Hawaii's schoolchildren: dietary patterns and caries prevalence. PMID- 4147499 TI - Caries prevalence in children from the United States. PMID- 4147500 TI - Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effects of alpha- and beta-adrenergic agents, histamine, serotonin and adenosine. PMID- 4147501 TI - The effect of the convulsant 3-mercaptopropionic acid on enzymes of the gamma aminobutyrate system in the rat cerebral cortex. PMID- 4147502 TI - An assay procedure for tryptamine in brain and spinal cord using its (3H)dansyl derivative. PMID- 4147503 TI - Activities of tyrosine aminotransferase in various human tissues. PMID- 4147504 TI - Effect of age, cryptorchidism and hypophysectomy on cyclic AMP concentration in rat testis. PMID- 4147505 TI - Cerebral arteritis: classification. PMID- 4147506 TI - Adrenergic control mechanism for ACTH secretion in man. PMID- 4147507 TI - Studies on the mechanism of iodination supported by thyroidal NADPH-cytochrome c reductase. PMID- 4147508 TI - A controlled one-year study of pipotiazine palmitate and fluphenazine decanoate in chronic schizophrenic syndromes. Evaluation of results at 6 and 12 months' trial. PMID- 4147509 TI - Pilot trials with long-acting pipotiazine injections. PMID- 4147510 TI - Clinical evaluation of a new depot neuroleptic. A pilot study with pipotiazine undecylenate (19.551 R.P.). PMID- 4147511 TI - Clinical experience with pipotiazine palmitate (19.552 R.P.) in Nordic countries. Report of a multicentre investigation. PMID- 4147512 TI - General evaluation of pipotiazine palmitate in hospitalized and open ward patients with functional psychosis. PMID- 4147513 TI - General evaluation of pipotiazine palmitate (19.552 R.P.) in hospitalized schizophrenic patients. PMID- 4147514 TI - Clinical evaluation of pipotiazine palmitate (19.552 R.P.) used on patients in an acute reception ward. PMID- 4147515 TI - Pipotiazine palmitate (19.552 R.P.) in the long-term treatment of chronic psychoses. A controlled trial on in-patients. PMID- 4147516 TI - Controlled clinical evaluation of depot neuroleptics. A double-blind trial with pipotiazine undecylenate and fluphenazine enanthate. PMID- 4147517 TI - Pharmacological study of pipotiazine (19.366 R.P.) and its undecylenic (19.551 R.P.) and palmitic (19.552 R.P.) esters. PMID- 4147518 TI - An obstetric and gynecologic associate program. PMID- 4147519 TI - Editorial: Bone-marrow transplants for immunodeficiency syndromes. PMID- 4147520 TI - Beta-adrenergic blockade in arrhythmias of acute myocardial infarction. PMID- 4147521 TI - Respiratory stimulants: review of the literature and assessment of current status. PMID- 4147522 TI - Metabolism of cholesteryl palmitate by rat brain in vitro; formation of cholesterol epoxides and cholestane-3beta,5alpha,6beta-triol. AB - Incubation of [4-(14)C]cholesteryl palmitate with the 12,000 g supernatant fraction of adult rat brain fortified with an NADPH-generating system and beta mercaptoethylamine resulted in formation (2-5%) of more polar metabolites characterized as a mixture of cholesterol-5,6-epoxides. Under extended incubation conditions, cholestane-3beta-5alpha-6beta-triol was isolated as the major end product of the incubations. Free [4-(14)C]cholesterol incubated under similar conditions was not oxidized, whereas oxidation of [4-(14)C]cholesteryl palmitate appeared to be dependent upon hydrolysis of the ester by the rat brain microsomal subcellular fraction. Elimination of the NADPH-generating system or the addition of EDTA to the incubation mixture inhibited epoxide formation, suggesting that the products are derived from an NADPH-dependent enzymatic lipoperoxidation mechanism. The in vitro conversion of [4-(14)C]cholesterol-5alpha,6alpha-epoxide to cholestane-3beta,5alpha,6beta-triol was also demonstrated in rat brain subcellular fractions in the absence of added cofactors. PMID- 4147523 TI - Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A. AB - A new assay for 3-hydroxy-3-methylglutaryl CoA reductase (mevalonate:NADP oxidoreductase [acylating CoA], EC 1.1.1.34) is based upon the measurement of released coenzyme A (SH) during the reduction of 3-hydroxy-3-methylglutaryl CoA to mevalonate. Coenzyme A was measured in the presence of dithiothreitol, required for activity, by reaction with 5,5'-dithiobis(2-nitrobenzoic acid). Sodium arsenite forms a complex with the dithiol, but not with monothiols. Thus, reduced coenzyme A reacts instantaneously with the reagent and dithiothreitol reacts slowly. The absorbance due to the coenzyme A-5,5'-dithiobis(2-nitrobenzoic acid) reaction is determined by extrapolating the linear (dithiol) absorbance time curve to the time of addition of the reagent. After subtraction of control absorbance (deletion of NADPH), the concentration of CoA-SH is calculated from epsilon(max) = 1.36 x 10(4) at 412 nm. The method of protein removal and reduction of sulfhydryl groups on the enzyme are critical. This method provides an immediate assay. Recovery of reduced coenzyme A was 98.7%. The assay is applicable for microsomes or purified enzyme and has an effective range of 0.5-50 nmoles of coenzyme A. It was applied to kinetic measurement of the pigeon liver microsomal enzyme reaction. The apparent K(m) value for 3-hydroxy-3 methylglutaryl CoA was 1.75 x 10(-5) M, and for NADPH the value was 6.81 x 10(-4) M. This method was compared with the dual-label method at high and low levels of activity. The data were not statistically different. PMID- 4147524 TI - Liver dehydrogenase levels in rainbow trout, Salmo gairdneri, fed cyclopropenoid fatty acids and aflatoxin B1. AB - Cyclopropenoid fatty acids in the diet of rainbow trout caused significant reductions in liver protein and activity of glucose-6-phosphate dehydrogenase, NADP-linked isocitrate dehydrogenase, lactate dehydrogenase, and malate dehydrogenase. Changes in total activity were usually accompanied by similar changes in specific activity. The activity of glucose-6-phosphate dehydrogenase appeared to be more sensitive to the ingestion of cyclopropenoid fatty acids than the other dehydrogenases studied. Feeding 20 ppb aflatoxin B(1) to rainbow trout did not significantly change the activity of the dehydrogenases except for a small increase in the activity of glucose-6-phosphate dehydrogenase after 21 days of feeding. Relationships of these changes to the cocarcinogenicity of cyclopropenoid fatty acids and the carcinogenicity of aflatoxin are discussed. PMID- 4147525 TI - The prune belly syndrome. Report of 20 cases and description of a lethal variant. PMID- 4147526 TI - [Clinical study of clindamycin-2-palmitate treatment in pediatric infections (author's transl)]. PMID- 4147527 TI - [Clinical studies on clindamycin-2-palmitate (author's transl)]. PMID- 4147528 TI - Histaminergic vasodilatation in the hindlimb of the dog. PMID- 4147529 TI - Fear, reinforcing activities and degree of alcoholism. A correlational analysis. PMID- 4147530 TI - Periodicity of susceptibility to pneumococcal infection: influence of light and adrenocortical secretions. AB - Circadian periodicity of susceptibility to pneumococcal infection was altered but not abolished in blind or adrenalectomized mice. Serum corticosterone concentrations 24 hours after pneumococcal challenge were greatest in animals challenged at 0400 hours, a time when circulatory corticosterone is lowest; the smallest absolute increase in serum corticosterone followed challenge at 1600 hours. PMID- 4147531 TI - Functions of baseplate components in bacteriophage T4 infection. I. Dihydrofolate reductase and dihydropteroylhexaglutamate. PMID- 4147532 TI - [A system for the further development of problem-solving capability]. PMID- 4147533 TI - [Intensity and time-related behavior of acoustically released changes in skin resistance]. PMID- 4147534 TI - [Graded rate of vigilance, evoked brain potentials, and optical reaction time in periodical acoustic stimulation]. PMID- 4147535 TI - [Method-related critical remarks on G. Diederich's et al. iteration procedure for incomplete data matrices]. PMID- 4147536 TI - Analysis of pineal and brain indole alkylamines by gas chromatography-mass spectrometry. PMID- 4147537 TI - Use of mass fragmentography to detect subcellular localization of drug metabolites acting as false transmitters. PMID- 4147538 TI - Effect of adrenergic receptor blockade on the response to prostaglandin E1 in canine ileum. PMID- 4147539 TI - Immunosuppression by the bisdioxopiperazines ICRF 154 and 159. PMID- 4147540 TI - Properties of purifed quinonoid dihydropterin reductase. PMID- 4147541 TI - Phospholipid and protein metabolism in mouse liver mitochondria during riboflavin deficiency and recovery. PMID- 4147542 TI - Some properties of a DNA-dependent RNA polymerase from Halobacterium cutirubrum. PMID- 4147543 TI - Loss of graft-versus-host reactivity of mouse lymphocytes during serial passage through irradiated allogeneic hosts. PMID- 4147544 TI - [Urinary abnormalities and agenesis of the muscles of the abdominal wall. "Prune belly" syndrome (author's transl)]. PMID- 4147545 TI - Program prototypes: programs in Philadelphia. PMID- 4147546 TI - Bacterial meningitis complicating cranial-spinal trauma. PMID- 4147547 TI - Studies on in vitro peroxidation of liver lipids in ethanol-treated rats. PMID- 4147549 TI - [Postvaccinal encephalopathy]. PMID- 4147548 TI - XXVII Wherry Memorial Lecture. Steroid therapy in otolaryngology. PMID- 4147550 TI - [Psycho-autonomic interrelationships in the pathology of various links in the limbic-reticular complex]. PMID- 4147551 TI - Pneumococcal serotypes associated with acute pneumonia. PMID- 4147552 TI - Impaired chronotropic response to beta-stimulation in chronic coronary artery disease. PMID- 4147553 TI - Interaction between catecholamines and vasopressin on renal medullary cyclic AMP of rat. PMID- 4147554 TI - Glucose-6-phosphate dehydrogenase Johannesburg: a new variant with reduced activity in a patient with congenital non-spherocytic haemolytic anaemia. PMID- 4147555 TI - The metabolism of salicylazosulphapyridine in ulcerative colitis. I. The relationship between metabolites and the response to treatment in inpatients. AB - The metabolism of salicylazosulphapyridine was studied in 16 patients with ulcerative colitis admitted to hospital. The acetylator phenotype was determined on admission. The mean serum concentration (mug/ml) (at steady state eight +/- two days in patients responding to treatment) of SASP, total SP, and 5-ASA were 18.7 +/- 12.8; 53.7 +/- 23.1; and 1 +/- 0.9 for slow acetylators and 17.6 +/- 7.1; 31 +/- 9.0 and 1 +/- 0.9 for fast acetylators respectively. Twenty-four hour urinary excretion of SASP, total SP, and 5-ASA were 4.6% +/- 3.1; 52% +/- 9.6 and 22.3 +/- 6.7% of the administered dose respectively. Serum total SP concentration of 20 to 50 mug/ml appeared to coincide with clinical improvement in the absence of any side effects related to salicylazosulphapyridine. No such relationship could be shown with serum SASP, individual metabolites, or 5-aminosalicyclic acid. PMID- 4147556 TI - Studies on the mechanism of action of the flavoenzyme lactate oxidase. Oxidation and elimination with beta-chlorolactate. PMID- 4147557 TI - Lipophilic interactions of organic cations with mitochondrial inner membranes during respiratory control. PMID- 4147558 TI - Isolation and properties of the envelope of spinach chloroplasts. PMID- 4147559 TI - Bacterial interference. II. Role of the normal throat flora in prevention of colonization by group A Streptococcus. PMID- 4147560 TI - Enzyme activities in regenerating epithelium during wound healing. IV. Aminotransferases and NADP-dependent enzymes. PMID- 4147561 TI - Rapid detection of gram-negative bacterial meningitis by the limulus lysate test. PMID- 4147562 TI - Letter: Use of thymus in Millipore chambers for immunologic reconstitution. PMID- 4147563 TI - Reduction in the concentration of nerve growth factor in mice after sialectomy and castration. PMID- 4147564 TI - [Prevention of premature labor with beta receptor stimulants]. PMID- 4147565 TI - Effects of D- and DL-propranolol on myocardial adenyl cyclase activity. PMID- 4147566 TI - Newly synthesized DNA and Bacillus subtilis DNA incorporated into transformable Diplococcus pneumoniae. PMID- 4147567 TI - The effects of Chrysaora and Physalia venoms on mitochondrial structure and function. PMID- 4147568 TI - [Hydrocele of abdominally retained testis]. PMID- 4147569 TI - Fluorescent spectra of lysergic acid diethylamide: observations on a gastric extract. PMID- 4147570 TI - Purification and properties of isocitrate dehydrogenase (NADP) from Thermus aquaticus YT-1, Bacillus subtilis-168 and Chlamydomonas reinhardti-Y-2. PMID- 4147571 TI - Sulfinic and sulfonic analogs of gamma-aminobutyric acid and succinate semialdehyde, new substrates for the aminobutyrate aminotransferase and the succinate semialdehyde dehydrogenase of Pseudomonas fluorescens. PMID- 4147572 TI - Specific changes in the activity of tyrosine aminotransferase isoenzymes in rat liver after cortisol treatment and partial hepatectomy. PMID- 4147574 TI - Tagetes minuta L., as a repellent and insecticide against adult mosquitoes. PMID- 4147573 TI - Parkinson's disease. A genetic study. PMID- 4147575 TI - [Histochemical aspects of primary and secondary myopathies (author's transl)]. PMID- 4147576 TI - Investigations on the catecholamine release in anaphylactic, anaphylatoxin, and histamine shock of quinea pigs. PMID- 4147577 TI - Serologic evidence for antigens controlled by the Ir region in mice. AB - Antibodies produced in B10.D2 mice against soluble lymphocyte membrane antigens of B10.A (H-2(a)) mice reacted only with lymphocytes of the strains carrying the Ir(k) region, i.e., B10.A(2R), B10.K, B10.BR, B10.HTT, AQR, A.TE, C3H, and CBA; they did not react with cells of strains carrying different Ir regions, i.e., B10.A(4R), B10, B10.M, A.SW, DBA/1. It is therefore concluded that the antigen detected with these antibodies is apparently controlled by the Ir region of the H 2 complex. The antigen is present on some T lymphocytes and absent on B lymphocytes. Its presence or absence seems to correlate with MLC and GVH reactivity. PMID- 4147578 TI - Induction of a primary antihapten response in vivo by a graft-vs.-host reaction. AB - A primary anti-NIP PFC response can be elicited by a GVH reaction provided certain structural requirements of the NIP-carrier are met. NIP-coated F(1) erythrocytes and NIP-coated parental erythrocytes give rise to substantial anti NIP PFC responses in F(1) mice after the injection of parental spleens. These conjugates do not of themselves give rise to an anti-NIP PFC response and, in fact, normally give rise to NIP-specific tolerance. In contrast the GVH reaction is not able to enhance the primary anti-NIP PFC response to immunogenic NIP conjugates. PMID- 4147579 TI - Cefazolin in the treatment of bacterial pneumonia. PMID- 4147580 TI - Evaluation of cefazolin in the treatment of bacterial endocarditis and bacteremia. PMID- 4147581 TI - The meaning of statistics in dental literature. PMID- 4147582 TI - Microbiologic studies on denture stomatitis. PMID- 4147583 TI - Cytochemical and ultrastructural alterations associated with confluent growth in cell cultures of epithelial-like cells from rat liver. PMID- 4147584 TI - [Fatal poisonings with carbromal and bromisoval]. PMID- 4147585 TI - [Panarteriitis nodosa]. PMID- 4147586 TI - H2-receptor blockade and stimulation of histidine decarboxylase. PMID- 4147587 TI - Neutral protease release from human leukocytes regulated by neurohormones and cyclic nucleotides. PMID- 4147588 TI - [Changes of heart repolarization through beta receptor blockade and its determination with spatial T-area vector in a decreasing heart rate]. PMID- 4147589 TI - [Etiology of arrhythmias in childhood]. PMID- 4147590 TI - A light and electron microscope study of the nervous system of Ceriantheopsis americanus (Cnidaria, Ceriantharia). PMID- 4147597 TI - [Current aspects of theapy of postoperative paralysis of the digestive tract (problem of stress disease in the digestive area)]. PMID- 4147598 TI - Release of DNA polymerase from rat liver chromatin on incubation with NAD. PMID- 4147599 TI - [Search for effective procedures for denitrogenation of the human body for the prevention of altitudinal decompression disorders]. PMID- 4147600 TI - [Study of the species makeup of human intestinal lactobacilli under the conditions of a prolonged stay in an enclosed space]. PMID- 4147601 TI - [Study of the decontaminating properties of sorbents used in the life support system of space ships]. PMID- 4147602 TI - International symposium on Hodgkin's disease. Conference held by the Stanford University School of Medicine, Stanford, California, March 20-24, 1972. PMID- 4147603 TI - Acute infectious sinusitis in cyanotic congenital heart disease. PMID- 4147604 TI - Mixed gonadal dysgenesis. PMID- 4147605 TI - The major influence of a magnetic field on a nickel surface used for an immunoelectroadsorption assay. PMID- 4147607 TI - Some aspects of the physiology of the autonomic nervous system. PMID- 4147606 TI - Immunochemical demonstration of increased accumulation of tyrosine hydroxylase protein in sympathetic ganglia and adrenal medulla elicited by reserpine. AB - Chronic administration of reserpine to rats increases, in sympathetic ganglia and adrenal medulla, the activity of tyrosine hydroxylase (EC 1.14.3.x), the enzyme catalyzing the rate-limiting step in the biosynthesis of catecholamines. Immunochemical titration of the enzyme in both adrenal gland and innervated superior cervical ganglia demonstrates that enhanced enzyme activity is entirely attributable to accumulation of more specific enzyme protein and not activation of preexistent enzyme molecules. PMID- 4147608 TI - Beta adrenergic blocking drugs. Present position and future development. PMID- 4147609 TI - [Study of the action of beta-adrenergic blockers in the treatment of angina pectoris]. PMID- 4147610 TI - Cardioselective beta blockade in hypertrophic cardiomyopathy. PMID- 4147611 TI - Effects of practolol administration on cardiac and renal function in patients with chronic atrial fibrillation. PMID- 4147612 TI - One hundred fifty cases of cardiac arrhythmias treated with acta practolol (I.C.I. 50.172). PMID- 4147613 TI - cardiac dysrhythmias during anaesthesia with special reference to practolol (Eraldine). PMID- 4147614 TI - Adrenergic beta receptor inhibition and hyperthyroidism. PMID- 4147615 TI - [Hemodynamic effects of a cardioselective beta-adrenergic inhibitor (ICI 50172) in coronary insufficiency. Preliminary results]. PMID- 4147616 TI - [Neurohumoral regulation of erythropoiesis]. PMID- 4147617 TI - [Erythropoiesis during the perinatal period and physiological mechanisms of its regulation]. PMID- 4147618 TI - [Neurohumoral regulation of kidney activity]. PMID- 4147619 TI - [Influence of thyroidectomy on 11 beta and 21-hydroxylation machanisms in adrenal cortex of the rat]. PMID- 4147620 TI - Production of superoxide ions in rat liver microsomes. PMID- 4147621 TI - [Biosynthesis of fatty acids in mouse brain microsomes]. PMID- 4147622 TI - [Soluble and particulate aldehyde dehydrogenases of Pseudomonas aeruginosa]. PMID- 4147623 TI - A "reagentless" fluorometric method for creatine kinase activity in serum. PMID- 4147624 TI - On the fractionation of halophilic enzymes with ammonium sulphate. PMID- 4147625 TI - European Organization for Caries Research. Abstracts of papers read. 20th Congress-Zurich, July 20 to 22, 1973. PMID- 4147626 TI - Evaluation of enzyme histochemical observations for metabolic studies. A combined histochemical and biochemical investigation of experimentally induced skeletal muscle-changes. I. The histochemical investigation. PMID- 4147627 TI - Tolerance to type 3 pneumococcal polysaccharide in monkeys. PMID- 4147628 TI - Accelerated skin graft rejection following transfer of cells sensitized to a "weak" histocompatibility antigen(s). PMID- 4147629 TI - Relationship between graft-vs-host reactivity and possession of the high leukemia genotype hr-hr. PMID- 4147630 TI - Tissue typing: an experimental solution in the chicken. PMID- 4147631 TI - Quantitative determination of antihistamines in pharmaceutical preparations by ultra violet spectrophotometry. PMID- 4147632 TI - [Treatment of arterial hypertension. Clinico-therapeutical aspects of a new association: potassium cancreonate of altizide-rescinnamine]. PMID- 4147633 TI - [Vasculat for intravenous infusion. Tolerance and therapeutic effects]. PMID- 4147634 TI - Letter: New antibacterial agent via photofluorination of a bacterial cell wall constituent. PMID- 4147635 TI - Letter: The effects of cardioactive drugs on the performance of cultured foetal hearts. PMID- 4147636 TI - Horizontal transmission of feline leukaemia virus. PMID- 4147637 TI - Increase in histamine receptors on thymus-derived effector lymphocytes during the primary immune response to alloantigens. PMID- 4147638 TI - Dissociation of lymphocyte activation and graft-versus-host competence of blood cells after skin grafting in rats treated with antithymocyte and normal pig serum. PMID- 4147639 TI - Immunocompetent lymphocytes in human and primate marrow. PMID- 4147640 TI - Depletion of complement during graft-versus-host reaction in a severe combined immunodeficiency patient after receiving a mismatched marrow transplant. PMID- 4147641 TI - Progress report on viral hepatitis. PMID- 4147642 TI - The gastroionogram. A new approach in the performance of gastric analysis. PMID- 4147643 TI - [Wermer's synerome or familial polyendocrine adenomatous hyperplasia (2 anatomo clinical cases)]. PMID- 4147644 TI - The physician manpower question revisited. PMID- 4147645 TI - Two malic enzymes in Pseudomonas aeruginosa. AB - Cell-free extract supernatant fluids of Pseudomonas aeruginosa were shown to lack malic dehydrogenase but possess a nicotinamide adenine dinucleotide (NAD)- or NAD phosphate (NADP)-dependent enzymatic activity, with properties suggesting a malic enzyme (malate + NAD (NADP) --> pyruvate + reduced NAD (NADH) (reduced NADP [NADPH] + CO(2)), in agreement with earlier findings. This was confirmed by determining the nature and stoichiometry of the reaction products. Differences in heat stability and partial purification of these activities demonstrated the existence of two malic enzymes, one specific for NAD and the other for NADP. Both enzymes require bivalent metal cations for activity, Mn(2+) being more effective than Mg(2+). The NADP-dependent enzyme is activated by K(+) and low concentrations of NH(4) (+). Both reactions are reversible, as shown by incubation with pyruvate, CO(2), NADH, or NADPH and Mn(2+). The molecular weights of the enzymes were estimated by gel filtration (270,000 for the NAD enzyme and 68,000 for the NADP enzyme) and by sucrose density gradient centrifugation (about 200,000 and 90,000, respectively). PMID- 4147646 TI - Reduced nicotinamide adenine dinucleotide oxidase activity and H2O2 formation of Mycoplasma pneumoniae. AB - Cell-free extracts of Mycoplasma pneumoniae showed two distinct reduced nicotinamide adenine dinucleotide (NADH(2)) oxidase activities in the supernatant fraction. By ammonium sulfate fractionation and polyacrylamide gel electrophoresis, one activity not requiring flavine co-factors was precipitated by 50 to 70% ammonium sulfate concentration and identified with a slower-moving band on acrylamide gel electrophoresis; a second NADH(2) oxidase activity was flavine mononucleotide (FMN) dependent and associated with a more rapidly moving band; it could only be partially precipitated by ammonium sulfate concentrations ranging from 50 to 100%. Studies with alternate electron acceptors indicated the presence of a menadione, a 2,6-dichlorophenol indophenol and a very weak ferricyanide oxido-reductase activity, but no cytochrome c oxido-reductase, in the cell-free preparations. The NADH(2) oxidase activities of all fractions were relatively cyanide insensitive and were only minimally inhibited by flavoprotein and other respiratory chain inhibitors. H(2)O(2) formation was negligible unless FMN, but not flavine adenine dinucleotide (FAD), was added to the crude NADH(2) oxidase system; upon fractionation and electrophoresis, the H(2)O(2) formation was associated with the FMN-dependent, more rapidly moving NADH(2) oxidase band. This FMN-dependent NADH(2) oxidase-H(2)O(2) generating system may be a mechanism for the H(2)O(2) formation observed during glucose oxidation in the intact organism. PMID- 4147647 TI - Regulation of the nicotinamide adenine dinucleotide- and nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenases of Saccharomyces cerevisiae. AB - Saccharomyces cerevisiae contains two distinct l-glutamate dehydrogenases. These enzymes are affected in a reciprocal fashion by growth on ammonia or dicarboxylic amino acids as the nitrogen source. The specific activity of the nicotinamide adenine dinucleotide phosphate (NADP) (anabolic) enzyme is highest in ammonia grown cells and is reduced in cells grown on glutamate or aspartate. Conversely, the specific activity of the nicotinamide adenine dinucleotide (NAD) (catabolic) glutamate dehydrogenase is highest in cells grown on glutamate or aspartate and is much lower in cells grown on ammonia. The specific activity of both enzymes is very low in nitrogen-starved yeast. Addition of the ammonia analogue methylamine to the growth medium reduces the specific activity of the NAD-dependent enzyme and increases the specific activity of the NADP-dependent enzyme. PMID- 4147648 TI - Purification and characterization of ferredoxin-nicotinamide adenine dinucleotide phosphate reductase from a nitrogen-fixing bacterium. AB - Evidence suggesting that Bacillus polymyxa has an active ferredoxin-NADP(+) reductase (EC 1.6.99.4) was obtained when NADPH was found to provide reducing power for the nitrogenase of this organism; direct evidence was provided when it was shown that B. polymyxa extracts could substitute for the native ferredoxin NADP(+) reductase in the photochemical reduction of NADP(+) by blue-green algal particles. The ferredoxin-NADP(+) reductase was purified about 80-fold by a combination of high-speed centrifugation, ammonium sulfate fractionation, and chromatography on Sephadex G-100 and diethylaminoethyl-cellulose. The molecular weight was estimated by gel filtration to be 60,000. A small amount of the enzyme was further purified by polyacrylamide gel electrophoresis and shown to be a flavoprotein. The reductase was specific for NADPH in the ferredoxin-dependent reduction of cytochrome c and methyl viologen diaphorase reactions; furthermore, NADP(+) was the acceptor of preference when the electron donor was photoreduced ferredoxin. The reductase also has an irreversible NADPH-NAD(+) transhydrogenase (reduced-NADP:NAD oxidoreductase, EC 1.6.1.1) activity, the rate of which was proportional to the concentration of NAD (K(m) = 5.0 x 10(-3)M). The reductase catalyzed electron transfer from NADPH not only to B. polymyxa ferredoxin but also to the ferredoxins of Clostridium pasteurianum, Azotobacter vinelandii, and spinach chloroplasts, although less effectively. Rubredoxin from Clostridium acidi-urici and azotoflavin from A. vinelandii also accept electrons from the B. polymyxa reductase. The pH optima for the various reactions catalyzed by the B. polymyxa ferredoxin-NADP reductase are similar to those of the chloroplast reductase. NAD and acetyl-coenzyme A, which obligatorily activate NADPH- and NADH ferredoxin reductases, respectively, in Clostridium kluyveri, have no effect on B. polymyxa reductase. PMID- 4147649 TI - Localization of alkaline phosphatase in three gram-negative rumen bacteria. AB - Of the three species (Bacteroides ruminicola, B. succinogenes, and Megasphaera elsdenii) of anaerobic gram-negative rumen bacteria studied, only B. ruminicola produced significant amounts of alkaline phosphatase. This enzyme, which is constitutive, showed a greater affinity for p-nitrophenylphosphate than for sodium-beta-glycerophosphate and was shown to be located exclusively in the periplasmic space of log-phase cells. Small amounts of this enzyme were released from these cells in stationary-phase cultures, but washing in 0.01 M MgCl(2) and the production of spheroplasts by using lysozyme in 0.01 M MgCl(2) did not release significant amounts of the enzyme. Exposure to 0.2 M MgCl(2) did not release significant amounts of the periplasmic alkaline phosphatase of the cell, and when these cells were spheroplasted with lysozyme in 0.2 M MgCl(2) only 25% of the enzyme was released. Spheroplasts were formed spontaneously in aging cultures of B. ruminicola, but even these cells retained most of their periplasmic alkaline phosphatase. It was concluded that the alkaline phosphatase of B. ruminicola is firmly bound to a structural component within the periplasmic area of the cell wall and that the enzyme is released in large amounts only when the cells break down. The behavior of alkaline phosphatase in this bacterium contrasts with that of conventional periplasmic enzymes of aerobic bacteria, which are released upon conversion into spheroplasts by lysozyme and ethylenediaminetetraacetic acid and by other types of cell wall damage. All three species of bacteria studied here, as well as bacteria found in mixed populations in the rumen, have thick, complex layers external to the double-track layer of their cell walls. In addition, B. ruminicola produces a loose extracellular material. PMID- 4147650 TI - Metabolic regulation by homoserine in Escherichia coli B-r. AB - A mathematical analysis of branched pathway regulation has led to the prediction of a novel homoserine control in Escherichia coli B. Experimental support for such control is presented in this paper. Homoserine, the precursor of both threonine and methionine, inhibits nicotinamide adenine dinucleotide phosphate (NADP(+))-specific glutamate dehydrogenase (EC 1.4.1.4), the enzyme catalyzing the first reaction in ammonia assimilation. Physiological and biochemical evidence for this effect are offered. Homoserine depresses the growth rate of the organism, and glutamate, the product of the inhibited reaction, reverses this effect. The NADP(+)-specific glutamate dehydrogenase activity in cell-free extracts is inhibited by homoserine, and this inhibition parallels the restriction of growth rate. These effects are found in other enteric bacteria which share a similar overall pattern of control for the amino acids derived from aspartate. On the other hand, a sampling of more distantly related species which have different pathways and/or regulatory patterns provides no evidence for homoserine inhibition of the glutamate dehydrogenase reaction. PMID- 4147651 TI - Formate dehydrogenase of Clostridium thermoaceticum: incorporation of selenium 75, and the effects of selenite, molybdate, and tungstate on the enzyme. AB - The formation of the nicotinamide adenine dinucleotide phosphate-dependent formate dehydrogenase in Clostridium thermoaceticum is stimulated by the presence of molybdate and selenite in the growth medium. The highest formate dehydrogenase activity was obtained with 2.5 x 10(-4) M Na(2)MoO(4) and 5 x 10(-5) Na(2)SeO(3). Tungstate but not vanadate could replace molybdate and stimulate the formation of formate dehydrogenase. Tungstate stimulated activity more than molybdate, and in combination with molybdate the stimulation of formation of formate dehydrogenase was additive. Formate dehydrogenase was isolated from cells grown in the presence of Na(2) (75)SeO(2), and a correlation was observed between bound (75)Se and enzyme activity. PMID- 4147652 TI - Inhibition of gamma-glutamylcysteine synthetase by L-methionine-S-sulfoximine. PMID- 4147653 TI - Reductase, phosphatase, and kinase activities in the metabolism of alkyldihydroxyacetone phosphate and alkyldihydroxyacetone. PMID- 4147654 TI - Regulation of glutamine synthetase activity of hepatoma tissue culture cells by glutamine and dexamethasone. PMID- 4147655 TI - Resolution and reconstitution of the mitochondrial electron transport system. IV. The reconstitution of rotenone-sensitive reduced nicotinamide adenine dinucleotide-ubiquinone reductase from reduced nicotinamide adenine dinucleotide dehydrogenase and phospholipids. PMID- 4147656 TI - Beta-adrenergic blocking agents. 14. Microbiological reduction of isopropylaminomethyl 2-naphthyl ketone to (R)-(--)-2-isopropylamino-1-(2 naphthyl)ethanol and related reductions. PMID- 4147657 TI - A study of the conformational requirements for direct adrenergic stimulation. PMID- 4147659 TI - Conformationally restricted analogs of histamine H1 receptor antagonists. Trans- and cis-1,5-Diphenyl-3-dimethylaminopyrrolidine. PMID- 4147658 TI - Quaternary salts of substituted 2-aminoethyl N-benzoylaminobenzoate. A new class of smooth muscle relaxant agents. PMID- 4147660 TI - Synthesis and inhibitory activity of new ethylenedioxyquinones as analogs of coenzyme Q. PMID- 4147661 TI - Lipogenesis in the ruminant: effect of fasting and refeeding on fatty acid synthesis and enzymatic activity of sheep adipose tissue. PMID- 4147662 TI - Diphtheria as a model. Introduction of serums and vaccines for scarlet fever and pneumococcal pneumonia. PMID- 4147664 TI - The European Environmental Mutagen Society. Abstracts of papers presented at the Third Annual Meeting, June 4th-7th, 1973. The Biomedical Centre, University of Uppsala (Sweden). PMID- 4147663 TI - Medical education in the United States, 1972-1973. PMID- 4147665 TI - Rheumatologic disorders due to immune complexes. PMID- 4147666 TI - Vesta variant of Tourette's disease: treatment with haloperidol. PMID- 4147667 TI - Bacterial inhibition of ureteral smooth muscle contractility: in vitro evaluation of potential inhibitory factors. PMID- 4147668 TI - Dehydrogenases in the prepubertal rat ovary: a histochemical study of delta-5-3 beta-hydroxysteroid dehydrogenase and enzymes of carbohydrate oxidation following oxythiamine treatment. PMID- 4147669 TI - Drug metabolism and drug-induced spectral interactions in human fetal liver microsomes. PMID- 4147670 TI - Effect of riboflavin deficiency on phenobarbital and 3-methylcholanthrene induction of microsomal drug-metabolizing enzymes of the rat. PMID- 4147671 TI - Effect of adjuvant disease in rats on cyclophosphamide and isophosphamide metabolism. PMID- 4147672 TI - Biosynthesis of slaframine, (1S,6S,8aS)-1-acetoxy-6-aminooctahydroindolizine, a parasympathomimetic alkaloid of fungal origin. I. Pipecolic acid and slaframine biogenesis. PMID- 4147675 TI - A year of continuing introspection, 1972-73. PMID- 4147673 TI - Biosynthesis of slaframine, (1S,6S,8aS)-1-acetoxy-6-aminooctahydroindolizine, a parasympathomimetic alkaloid of fungal origin. II. The origin of pipecolic acid. PMID- 4147674 TI - The reduction of vinyl side-chains of Mg-protoporphyrin IX monomethyl ester in vitro. PMID- 4147676 TI - Studies on rat-liver microsomal cholesterol 7alpha-hydroxylase. PMID- 4147677 TI - NADP-linked isocitrate dehydrogenase from beef liver. Purification, quaternary structure and catalytic activity. PMID- 4147678 TI - BC-105--a new prophylactic agent for migraine--four years' experience in seventy five patients. PMID- 4147679 TI - A new look at respiratory stimulants. PMID- 4147680 TI - Electron transfer from alpha-reduced nicotinamide adenine dinucleotide to flavoprotein, cytochromes, and mixed function oxidases of rat liver microsomes. PMID- 4147682 TI - The dental health of Indian children in the Sioux Lookout Zone of Northwestern Ontario. PMID- 4147681 TI - The effect of vitamin B12 deprivation on the enzymes of fatty acid synthesis. PMID- 4147683 TI - A comparison of gas-liquid chromatographic retention indices on support-coated open tubular columns and on packed columns for a series of central nervous stimulant drugs. PMID- 4147684 TI - N-substituted 2-amino-1-(2-thienyl)ethanols as beta-adrenergic blocking agents. PMID- 4147685 TI - Benzhydryl and fluorenyl lactamimides with hypoglycemic, diuretic, blood platelet aggregation inhibitory, and antiinflammatory activities. PMID- 4147687 TI - [Impression on the General Meeting of the Japan Midwife Association]. PMID- 4147686 TI - Glutaryl-S-(p-bromobenzyl)-L-cysteinylglycine. A metabolically stable inhibitor of glyoxalase I. PMID- 4147688 TI - [Report on the General Meeting of the Japan Midwife Association]. PMID- 4147689 TI - [Diagnostic significance of enzyme activity determination in ascites]. PMID- 4147690 TI - [Therapy of intoxications due to hypnotics in an intensive care unit (author's transl)]. PMID- 4147691 TI - [A comparison of antibodies labelled with fluorochrom or with enzyme for the demonstration of adenoviruses in cell cultures (author's transl)]. PMID- 4147692 TI - [A comparison of antibodies labelled with FITC or with peroxidase for the demonstration of adenovirus types 1 to 7 (author's transl)]. PMID- 4147693 TI - [Haemagglutination-inhibiting antibodies against arboviruses in human sera from different regions in Steiermark (Austria). I (author's transl)]. PMID- 4147694 TI - Haemagglutination-inhibiting antibodies against arboviruses in animal sera, collected in some regions in Austria. II. PMID- 4147695 TI - [Demonstration of precipitating antibodies against Coxsackie virus type B5, using acetate foil electrophoresis (author's transl)]. PMID- 4147696 TI - [Studies on the pH- and nitrite-sensitivity of various bacteriophages of staphylococci and Enterobacteriaceae (author's transl)]. PMID- 4147697 TI - [Influence of aeration conditions in fermentation cultures on the chemical composition of Salmonella lipopolysaccharides (author's transl)]. PMID- 4147698 TI - The occurrence of three different lipopolysaccharide cores in shigella and their relationship to known enterobacterial core types. PMID- 4147699 TI - The pathogenicity of Listeria monocytogenes. PMID- 4147701 TI - [Further studies on Nocardia bacteriophages (author's transl)]. PMID- 4147700 TI - Differential media in the isolation of Listeria monocytogenes. PMID- 4147702 TI - Nation-wide survey of antibiotic resistance by means of a computer. PMID- 4147703 TI - [Epidemiological and serological prospective study on Toxoplasma gondii infection (author's transl)]. PMID- 4147704 TI - Treating sleep disorders. PMID- 4147705 TI - Serum inorganic fluoride concentrations during and after halothane, fluroxene, and methoxyflurane anesthesia in man. PMID- 4147706 TI - Accuracy of gas standards used for mayo vapor analyzer calibration. PMID- 4147707 TI - Dirofilaria immitis. A cause of pulmonary coin lesions in human beings. PMID- 4147708 TI - Caries prevention by daily fluoride mouthrinsing. Report of a three-year clinical trial. PMID- 4147709 TI - Respiratory tract infections in children. B. Lower respiratory tract disease. PMID- 4147710 TI - Potentiation of therapeutic effects of nicotinic acid by pyridoxine in chronic schizophrenics. PMID- 4147711 TI - Clomipramine HCL--a double-blind study of a new antidepressant drug. PMID- 4147712 TI - Comparison of the effects of fluoride drinking water on caries frequency and mottled enamel in three similar regions of Austria over a 10-year period. PMID- 4147713 TI - [Participation of humoral factors in the lateral inhibition of the skin mechanoreceptors]. PMID- 4147714 TI - Meeting the dental treatment needs of indigent rural children. PMID- 4147715 TI - Thrombophlebitis migrans. An unusual presentation as a collagen vascular disease- report of a case. PMID- 4147716 TI - Model dehydrogenase reactions. Reduction of N-methylacridinium ion by reduced nicotinamide adenine dinucleotide and its derivatives. PMID- 4147717 TI - The computer in family practice. PMID- 4147718 TI - Open-closed-mindedness and the physician's assistant: an exploratory study. PMID- 4147719 TI - The effect of a beta-blocker on plasma renin activity of hypertensive patients. PMID- 4147720 TI - Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro. PMID- 4147721 TI - Combined treatment of hypertension with vasodilatation and beta-adrenergic blockade. PMID- 4147722 TI - Insecticidal activity of recent bacterial isolates and their toxins against mosquito larvae. PMID- 4147723 TI - 5-Hydroxytryptophan-induced myoclonus in guinea pigs and the possible role of serotonin in infantile myoclonus. PMID- 4147724 TI - Drug-induced catalepsy as influenced by convulsant and anticonvulsant drugs. PMID- 4147725 TI - Effects of various depressant drugs on deprivation-induced water consumption. PMID- 4147727 TI - Pennsylvania success story. Physician expander concept passes test. PMID- 4147726 TI - The relative importance of dopaminergic and noradrenergic neuronal systems for the stimulation of locomotor activity induced by amphetamine and other drugs. PMID- 4147728 TI - [On the apical organ (statocyst) of Pleurobrachia pileus (author's transl)]. PMID- 4147729 TI - [The multiplication of herpes simplex virus in the different phases of the cell cycle of synchronized HEp-2 cells (author's transl)]. PMID- 4147730 TI - [Virological and serological investigations on the role of birds as hosts of arboviruses in Eastern Austria (author's transl)]. PMID- 4147731 TI - [Isolation of a virus pathogenic for mice from Ixodes ricinus ticks in Northrhine Westphalia and Suabia (author's transl)]. PMID- 4147732 TI - [The immune response by application of isolated procapsids of poliovirus type 1 and coxsackievirus type B4 (author's transl)]. PMID- 4147733 TI - [Leukocidin from staphylococci of different origin (author's transl)]. PMID- 4147734 TI - Transduction among group A Streptococci: transducibility of strains representative of thirty different M types. PMID- 4147735 TI - [Biochemical types of Salmonella typhimurium with consideration also of tetrathionate-reductase (author's transl)]. PMID- 4147736 TI - [Biosynthesis of indole in not aerated cultures of Klebsiella aerogenes (author's transl)]. PMID- 4147737 TI - [The occurrence of neuraminidase and acylneuraminate pyruvate-lyase in Fusobacterium polymorphum and their pathogenetic role (author's transl)]. PMID- 4147738 TI - [Identification and medical importance of 8 Clostridium species isolated from pathological material (author's transl)]. PMID- 4147739 TI - [The demonstration of pathogenic mycobacteria by culture and by animal inoculation (author's transl)]. PMID- 4147740 TI - Assimilation of guanidoacetic acid by Sporothrix schenckii. PMID- 4147741 TI - [Isolation of one lysozyme fraction from hen-egg-white by column chromatography (author's transl)]. PMID- 4147742 TI - [Polyacrylamide gel (PAA) as a substratum of bacteriological culture media (author's transl)]. PMID- 4147743 TI - [Serological studies on the occurrence of Toxoplasma gondii among wild living mammalia in Eastern Austria (author's transl)]. PMID- 4147744 TI - [The incidence of Schistosoma haematobium (Bilharz) and Schistosoma mansoni (Sambon) in urban populations of Accra-Ghana and of Kaduna-Nigeria (author's transl)]. PMID- 4147745 TI - [Selective isolation of Bordetella bronchiseptica (author's transl)]. PMID- 4147746 TI - A new primary-care medical practitioner. PMID- 4147747 TI - A new primary-care medical practitioner. PMID- 4147748 TI - Herniography: a diagnostic refinement in the management of cryptorchidism. PMID- 4147749 TI - Practolol blockade of cardiac but not vascular or uterine beta-adrenergic receptors in the anesthetized cat. PMID- 4147750 TI - Systemic and renal hemodynamic effects of a new alpha-adrenergic blocking agent: NC 7197. PMID- 4147751 TI - On the lipid mobilization induced by oxyfedrine in the dog and the rat. PMID- 4147752 TI - Fine control of citrate synthase activity in blue-green algae. PMID- 4147753 TI - Myocardial reactive hyperemia and coronary vascular reactivity in the dog. PMID- 4147754 TI - Revised normal ranges for six serum enzymes: further statistical analysis and the effects of different treatments of blood specimens. PMID- 4147755 TI - Antagonism of the effects of purinergic nerve stimulation and exogenously applied ATP on the guinea-pig taenia coli by 2-substituted imidazolines and related compounds. PMID- 4147756 TI - [The childless marriage: male sterility]. PMID- 4147757 TI - [Results of glucose tolerance tests and changes in inorganic serum phosphate and potassium levels in schizophrenic patients responding to treatment with psychotropic drugs]. PMID- 4147758 TI - Subjective symptoms of acute asthma within a heterogeneous sample of asthmatics. PMID- 4147759 TI - Prevalence of dental caries in twins. PMID- 4147761 TI - Five years observation on the dental caries experience of the "Saisiat" tribe aboriginal children in Taiwan. PMID- 4147760 TI - A clinical evaluation of a stannous fluoride and a sarcosinate dentifrice. PMID- 4147762 TI - Effects of axonal injury on norepinephrine, tyrosine hydroxylase and monoamine oxidase levels in sympathetic ganglia. PMID- 4147763 TI - Dopaminergic neurons in explants of substantia nigra in culture. PMID- 4147764 TI - The rapid differential diagnosis of meningitis. PMID- 4147765 TI - Selective inhibitor of slow reacting substance of anaphylaxis. PMID- 4147766 TI - A revision of the subfamily Haplorchinae Looss, 1899 (Trematoda: Heterophyidae). II. Genus Galactosomum. PMID- 4147767 TI - II. Deutsch-Franzosisches Dkompaktseminar: Schulische und auss erschulische Behandlungs- und Forderungszentren swie sonderpadagogische Freizeritprogramme fur verhaltensauffallige Kinder im Rheinland. PMID- 4147768 TI - The effect of alpha adrenergic block on adenosine- and ATP-induced coronary vasodilation. PMID- 4147769 TI - Temperature-dependent toxicity of adrenegic agonists in mice as a basis for treating d-amphetamine poisoning. PMID- 4147771 TI - [Vascular lesions of the liver and of the spleen in Zoster generalisatus (author's transl)]. PMID- 4147770 TI - Influences of splanchnic blood flow on epinephrine-induced hyperkalemia. PMID- 4147772 TI - [Therapeutic contributions of blocking and stimulation of the alpha and beta adrenergic receptors]. PMID- 4147773 TI - Glutamate dehydrogenase--ligand complexes and their relationship to the mechanism of the reaction. PMID- 4147774 TI - [Control and prevention of occupational cancers. Information from a report of the International Labor Organisation (I.L.O.) on a convention of experts]. PMID- 4147775 TI - A method for assaying activity and some other properties of NADP-oxidoreductase from Rhodotorula mucilaginosa. PMID- 4147776 TI - Enhancement of hepatic tyrosine aminotransferase induction in the rat by 5 fluorouracil. PMID- 4147777 TI - Epimerization of an intermediary metabolite of norethynodrel by a 3 beta-hydroxy delta 5(10)-steroid epimerase. PMID- 4147778 TI - Structure-activity relationships on the induction of hepatic microsomal enzymes in the mouse by 1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane(DDT) analogs. PMID- 4147779 TI - Effect of oudenone on adrenal tyrosine hydroxylase activity in vivo and on tissue catecholamine concentrations. PMID- 4147780 TI - Development of cardiovascular responses to autonomic blockade in intact fetal and neonatal lambs. PMID- 4147781 TI - The need for treatment in 11 to 17-year-old children. A longitudinal epidemiological study. PMID- 4147782 TI - Fluoride in the prevention of dental caries. A tentative cost-benefit analysis. PMID- 4147783 TI - Fluoride in the prevention of dental caries. A tentative cost-benefit analysis. PMID- 4147784 TI - Fluoridation of domestic salt after three years. PMID- 4147785 TI - [3'-Cyanophenylalcanolamine: a contribution to the study of selective beta adrenomimetic compounds]. PMID- 4147786 TI - [Antimicrobial action 1,2,4-benzothiadiazine-1,1-dioxide derivatives. IV]. PMID- 4147787 TI - Observations on the postmortem histochemistry of myofibers from stress susceptible pigs. PMID- 4147788 TI - [Treatment of peptic ulcer with methyluracil in combination with quateron]. PMID- 4147789 TI - 11-dehydrocorticosterone (compd. A) formation by the Microtus adrenal. PMID- 4147790 TI - Effect of biliary obstruction on formation and metabolism of bile acids in rat. PMID- 4147791 TI - [The properdin system in patients with schizophrenia during the process of active therapy]. PMID- 4147792 TI - Occupational, accidental, explorational carbon dioxide inhalation poisonings, and prevention. PMID- 4147793 TI - Determinations of amino acid, cation and reduced glutathione levels in the red cells of Awassi sheep (Qvis aries). PMID- 4147794 TI - Phosphate excretion in the laying fowl. PMID- 4147795 TI - Thermoregulatory responses of the arid zone kangaroos, Megaleia rufa and Macropus robustus. PMID- 4147796 TI - Effect of various gastrointestinal hormones and vasoactive substances on villous motility. PMID- 4147797 TI - Respiration of some urodele and anuran amphibia. I. In water, role of the skin and gills. PMID- 4147798 TI - Rate of digestion in Ophiocephalus punctatus Bloch. PMID- 4147799 TI - Some alterations in hemolymph proteins of Hemigrapsus nudus associated with temperature acclimation. PMID- 4147800 TI - Effects of estradiol and testosterone on cyclic AMP levels in certain tissues of domestic fowl (Gallus domesticus). PMID- 4147801 TI - Respiration of some urodele and anuran amphibia. II. In air, role of the skin and lungs. PMID- 4147802 TI - Galactose toxicity in chick cells in vitro. PMID- 4147803 TI - Lysine transport in turtle ventricle. I. Effect of ouabain and extracellular ions on lysine accumulation. PMID- 4147804 TI - Lysine transport in turtle ventricle. II. Effect of extracellular ions and ouabain on lysine fluxes. PMID- 4147805 TI - On the tongue of a hummingbird: its role in the rate and energetics of feeding. PMID- 4147806 TI - Plasma volume changes in ground squirrels during water deprivation. PMID- 4147807 TI - Carotenoid pigments in goldfish (Carassius auratus L.). VI. The effect of ACTH and phenylthiourea on the discoloration and the carotenoid metabolism. PMID- 4147808 TI - II. Enhancement of the catalytic activity of the human placental 17 beta oestradiol dehydrogenase by carboxymethylation of an histidyl residue of the active site. PMID- 4147809 TI - Pharmacology. New discoveries and the sympathetic nervous system. PMID- 4147810 TI - [Impression on the 15th International Congress of Nursing in Mexico. Interview with Ms. Pumie Kobayashi, President of the Japan Nursing Association]. PMID- 4147811 TI - [Presentation of patients]. PMID- 4147812 TI - [Impotentia erectionis--therapeutic attempt using bamethan sulfate, synephrine, and coffeinum purum]. PMID- 4147813 TI - Vasodilatation in the nasal mucosa of the cat and the effects of parasympatholytic and beta-adrenergic blocking agents. PMID- 4147814 TI - Population density and social pathology in mice. Differences in catecholamine metabolism associated with differences in behavior. PMID- 4147815 TI - The insect-repellant value of Ocimum SPP. (Labiatae): traditional anti-mosquito plants. PMID- 4147816 TI - Involvement of the alpha-adrenergic receptor in the phospholipid effect in rat parotid. PMID- 4147821 TI - Bronchogenic cyst. PMID- 4147824 TI - Are you satisfied with your CME? PMID- 4147817 TI - Training the family nurse practitioner. PMID- 4147827 TI - Letter: Some effects of irradiation and delayed amputation upon regeneration in Tubularia crocea. PMID- 4147828 TI - Conformation of pyridine nucleotides studied by phosphorus-31 and hydrogen-1 fast fourier transform nuclear magnetic resonance spectroscopy. III. Oxidized and reduced dinucleotides. PMID- 4147829 TI - The sored horse and the Horse Protection Act of 1970. PMID- 4147830 TI - Time orientation in the positive and negative free phantasies of mildly abnormal versus normal high school males. PMID- 4147831 TI - Curvilinear trends in outcome research. PMID- 4147833 TI - Factor structure of the MMPI-168 in a psychiatric population. PMID- 4147832 TI - Pleasant activities and depression. PMID- 4147834 TI - Effects of mosquitoes on the average daily gain of Hereford and Brahman breed steers in southern Louisiana. PMID- 4147835 TI - Beta-adrenoceptor blocking agents. 1. Cardioselective 1-aryloxy-3 (aryloxyalkylamino)propan-2-ols. PMID- 4147836 TI - Potential bioreductive alkylating agents. 2. Antitumor effect and biochemical studies of naphthoquinone derivatives. PMID- 4147837 TI - Potential histamine H2-receptor autagonists. 1. Aminoethylimidayo(1,2-a)pyridines and -imidayo(1,5-a)pyridines. PMID- 4147839 TI - Antimetabolites of coenzyme Q. 20. Synthesis of new alkyl-5,8-quinoxalinequinones as potential inhibitors of coenzyme Q and as antimalarial drugs. PMID- 4147838 TI - Nitrofuryl heterocyclics. 3. PMID- 4147840 TI - [Immunological problems of transplantation of organs and tissues]. PMID- 4147841 TI - [Surgico-technical problems and characteristics of lung transplantation]. PMID- 4147842 TI - [Use of beta receptor blockaders in diabetic patients]. PMID- 4147843 TI - The erythroid cells and haemoglobins of the chick embryo. PMID- 4147844 TI - [Influence of enzymatic induction on drug action (author's transl)]. PMID- 4147845 TI - [Distribution of Culicidae (Diptera, Nematocera) in Switzerland]. PMID- 4147846 TI - Fluorouracil effect on cytochrome c reductase activity of rat liver cell endoplasmic reticulum following partial hepatectomy. PMID- 4147847 TI - Relationship of racetrack surface to lameness in the thoroughbred racehorse. PMID- 4147848 TI - Effects of the immunosuppressant methotrexate in ponies. PMID- 4147849 TI - Role of the redox state of nicotinamide adenine dinucleotides in the in vivo regulation of inositol biosynthesis in Neurospora crassa. PMID- 4147850 TI - Abdominoscrotal hydrocele. PMID- 4147851 TI - The WIRL-3 rat liver cell lines and their transformed derivatives. PMID- 4147852 TI - International group agrees to write world cancer standard. PMID- 4147853 TI - Comparative dependence on adrenergic neural tone by automaticity in the sinus node and in the atrioventricular junction. PMID- 4147854 TI - Coronary and myocardial effects of dopamine in the conscious dog: parasympatholytic augmentation of pressor and inotropic actions. PMID- 4147855 TI - [Adhesion of the tendon of the m. flexor hallucis longus following tibial fracture]. PMID- 4147856 TI - [Experiences in the treatment of trochenteric fractures]. PMID- 4147857 TI - [Treatment of covered tendon injuries associated with abruption of the distal phalanx base]. PMID- 4147858 TI - [Tap epiphysis. Appearance of ossification disorders of various origin]. PMID- 4147859 TI - [The value and applicability of intraosseous venography in the evaluation of the blood circulation in the femur head following femur neck fracture]. PMID- 4147860 TI - [Modified internal fixation of varus derotation of femur osteotomy in childhood]. PMID- 4147861 TI - [Technic of isolated veloplasty]. PMID- 4147862 TI - [Elbow dislocation complicated by diaphyseal fracture of the radius]. PMID- 4147863 TI - [Intraosseous epidermoid cyst following phalanx fracture]. PMID- 4147864 TI - [Bilateral shoulder dislocation in a patient with multiple injuries]. PMID- 4147865 TI - [Erraneously diagnosed and treated knee injury]. PMID- 4147866 TI - Communication in health. PMID- 4147867 TI - Transient bactericidal defect of peripheral blood phagocytes from children with acute lymphoblastic leukemia receiving craniospinal irradiation. PMID- 4147868 TI - [Gamma glutamyltranspeptidase and liver diseases]. PMID- 4147869 TI - Mesenteric arteritis with extensive intestinal gangrene. PMID- 4147870 TI - [The behavior of Rickettsia montana and R. canada in body lice]. PMID- 4147871 TI - Contribution to the study of digestion in ticks: histology and fine structure of the midgut ephithelium of Ornithodorus moubata, Murray (Ixodoidea, Argasidae). PMID- 4147872 TI - Structure and function of the basal lamina and of the cell junctions in the midgut epithelium (stomach) of female Aedes aegypti L.(Insecta, Diptera). PMID- 4147873 TI - [The biology of a diurnal rodent from the Sahara, the "Goundi" (Ctenodactylidae)]. PMID- 4147874 TI - Reproductive biology of Eonycteris spelaea, Dobson (Megachiroptera) in West Malaysia. PMID- 4147875 TI - The persistence of smallpox in remote unvaccinated villages during eradication program activities. PMID- 4147876 TI - Detection of malarial antibodies in man by fluorescent antibody test using Plasmodium gallinaceum as antigen. PMID- 4147877 TI - New animal reservoirs of T. rhodesiense sleeping sickness. PMID- 4147878 TI - The effect of cordycepin on tsetse-borne Trypanosoma vivax infections. PMID- 4147879 TI - The effect of beta-blockade on coronary and systemic circulation in dogs at rest and during adaptation to exercise. PMID- 4147880 TI - Thymoxamine on the guinea-pig vas deferens: an effect unrelated to alpha-receptor blockade. PMID- 4147881 TI - The effect of autonomic blocking agents on the cardiovascular response to etoxadrol (CL 1848). I. Ganglionic blockade. PMID- 4147882 TI - The effect of autonomic blocking agents on the cardiovascular response to etoxadrol (CL 1848). II. Beta adrenergic blockade. PMID- 4147883 TI - Hydroxylation of geraniol and nerol by a monooxygenase from Vinca rosea. PMID- 4147884 TI - Co-purification of three folate enzymes from porcine liver. PMID- 4147885 TI - A branching reaction mechanism of glutathione reductase. PMID- 4147886 TI - Catalytic activity and EPR signals of DPNH dehydrogenase in relation to the acquisition and loss of piericidin sensitivity and of coupling site 1. PMID- 4147888 TI - Desaturation of phosphatidylcholine and phosphatidylethanolamine by a microsomal enzyme system from Candida lipolytica. PMID- 4147887 TI - Reduced nicotinamide-adenine dinucleotide-nitrite reductase from Azotobacter chroococcum. AB - 1. The assimilatory nitrite reductase of the N(2)-fixing bacterium Azotobacter chroococcum was prepared in a soluble form from cells grown aerobically with nitrate as the nitrogen source, and some of its properties have been studied. 2. The enzyme is a FAD-dependent metalloprotein (mol.wt. about 67000), which stoicheiometrically catalyses the direct reduction of nitrite to NH(3) with NADH as the electron donor. 3. NADH-nitrite reductase can exist in two either active or inactive interconvertible forms. Inactivation in vitro can be achieved by preincubation with NADH. Nitrite can specifically protect the enzyme against this inactivation and reverse the process once it has occurred. 4. A. chroococcum nitrite reductase is an adaptive enzyme whose formation depends on the presence of either nitrate or nitrite in the nutrient solution. 5. Tungstate inhibits growth of the microorganism very efficiently, by competition with molybdate, when nitrate is the nitrogen source, but does not interfere when nitrite or NH(3) is substituted for nitrate. The addition of tungstate to the culture media results in the loss of nitrate reductase activity but does not affect nitrite reductase. PMID- 4147889 TI - In vitro steroidogenesis in feline testes. PMID- 4147890 TI - Cognitive functioning and degree of psychosis in schizophrenics given many electroconvulsive treatments. PMID- 4147892 TI - Radiotelemetry of cardiovascular responses to exercise and diving in penguins. PMID- 4147891 TI - Transport of some non-electrolytes through amphibian skins. PMID- 4147893 TI - Specific effect of bull seminal ribonuclease (AS RNase) on cell systems in mice. PMID- 4147894 TI - Trimodal gas exchange in the large aquatic salamander, Siren lacertina (Linnaeus). PMID- 4147895 TI - The effects of valinomycin on striated muscles of the frog and the crayfish. PMID- 4147896 TI - Effect of temperature upon cell division, RNA and protein synthesis of cultured fathead minnow cells. PMID- 4147897 TI - An estimate of the heat balance of a nesting hummingbird in a chilling climate. PMID- 4147898 TI - Carbonic anhydrase activity in Arenicola marina (L.). PMID- 4147899 TI - Utilization of dietary urea by the kangaroo island wallaby Protemnodon eugenii (Desmarest). PMID- 4147900 TI - The lactate dehydrogenase isozymes of Coregonus hoyi gill (Pices: Salmonidae): tissue distribution, immunochemistry and molecular weight. PMID- 4147901 TI - Interspecific variation in the levels of intestinal alkaline phosphatase, adenosine triphosphatase and disaccharidases. PMID- 4147902 TI - The effects of anoxia on the respiratory movements of the hatching chick. PMID- 4147903 TI - Psychotropic drug-induced transformations of visual space. PMID- 4147904 TI - The effect of iron deficiency on respiration and energy-coupling in Escherichia coli. PMID- 4147905 TI - Terminal respiration in Moraxella lwoffi (NCIB 8250). PMID- 4147906 TI - Bacterial attack on phenolic ethers. Resolution of a Nocardia O-demethylase and purification of a cytochrome P 450 component. PMID- 4147907 TI - Effects of hyperoxia on oxidized and reduced NAD and NADP concentrations in Escherichia coli. PMID- 4147908 TI - The actions of drugs on the smooth muscle of the capsule and blood vessels of the spleen. PMID- 4147909 TI - The second-class doctor and the medical assistant in South Africa. PMID- 4147910 TI - A potential new method of identifying animal species and mosquito blood meals by the haemoglobin crystallization technique. PMID- 4147911 TI - The biting cycles of Mansonia bonneae, M. dives, M. indiana and M. uniformis in Southern Thailand. PMID- 4147912 TI - Reduction of ketones in liver cytosol. PMID- 4147913 TI - Comparative oxidative metabolism of aflatoxin B1 and palmotoxins B0 and G0 by rat liver microsomal fractions. PMID- 4147914 TI - Azo reduction of salicyl-azo-sulphapyridine in germ-free and conventional rats. PMID- 4147915 TI - Redox potential in caecal contents of the rat and azo reduction of salicyl-azo sulphapyridine. PMID- 4147917 TI - [Problems of use trials of long-acting tranquilizers in acute psychiatric syndromes]. PMID- 4147916 TI - The colitis of Behcet's disease: a separate entity? Colonoscopic findings and literature review. PMID- 4147919 TI - Intersexual problems. PMID- 4147918 TI - Regulation of nitrate reductase of Neurospora at the level of transcription and translation. AB - The presence of nitrate is required for the induced synthesis of NADPH-nitrate reductase and its related partial activity Benzyl Viologen-nitrate reductase in a wild-type strain of Neurospora. In nit-3, a mutant lacking complete NADPH-nitrate reductase activity but retaining the partial activity Benzyl Viologen-nitrate reductase, the presence of nitrate ions is not required for the de-repressed synthesis of the latter enzyme. The accumulation of the capacity to synthesize nitrate reductase, and the related Benzyl Viologen-nitrate reductase, in the absence of protein synthesis does not require nitrate in the normal strain or in strain nit-3. Ammonia antagonizes the accumulation of this capacity in both strains. Nitrate is required for the synthesis of nitrate reductase and related activities from presumedly preformed mRNA in the wild-type strain. Nitrate is not required for the comparable function in strain nit-3. Ammonia appears to stop the synthesis of nitrate reductase and related activities from presumedly preformed mRNA in the wild-type strain and in strain nit-3. The effects of nitrate, or ammonia and of no nitrogen source on the induced synthesis of nitrate reductase cannot be explained on the basis of the effects of the different nitrogen sources on general synthesis of RNA or of protein. PMID- 4147920 TI - British usage and American awareness of some new therapeutic drugs. PMID- 4147921 TI - The relationship between skin structure and transepidermal water loss. PMID- 4147923 TI - Erythrocyte 2,3-diphosphoglycerate in normal and porphyric fetal, neonatal and adult cattle. PMID- 4147922 TI - Factors affecting plasma ceruloplasmin activity in Gallus domesticus. PMID- 4147924 TI - Temperature regulation in the platypus, Ornithorhynchus anatinus (Shaw). PMID- 4147925 TI - Tissue glycogen levels in the Weddell seal, Leptonychotes weddelli: a possible adaptation to asphyxial hypoxia. PMID- 4147926 TI - Effects of temperature, photoperiod and season on in vitro metabolic rates of tissues from Thamnophis sirtalis parietalis, a cold climate reptile. PMID- 4147927 TI - Role of hepatic glycogenolytic enzymes in the cold-induced hyperglycemia of the killifish, Fundulus heteroclitus. PMID- 4147928 TI - The effect of salinity and temperature on the heart rate of osmoregulating and osmoconforming shrimps. PMID- 4147929 TI - Water content and distribution of tritiated water in tissues of Australian desert rodents. PMID- 4147930 TI - The responses of three species of bivalve mollusc to declining oxygen tension at reduced salinity. PMID- 4147931 TI - Influence of seasonal temperatures on the energy budget and metabolic rates of the northern two-lined salamander Eurycea bislineata bislineata. PMID- 4147933 TI - Critical thermal maxima of turtles: validity of body temperature. PMID- 4147932 TI - Amine excretion in excysted larvae and adults of Trichinella spiralis. PMID- 4147934 TI - Effects of acclimation on metabolic rate and thermal tolerance in the carpenter frog, Rana vergatipes. PMID- 4147935 TI - Sodium uptake by the sailfin molly, Poecilia latipinna: kinetic analysis of a carrier system present in both fresh-water-acclimated and sea-water-acclimated individuals. PMID- 4147936 TI - Daily and seasonal variation in metabolic response to cold during rest and forced exercise in the common redpoll. PMID- 4147937 TI - Partial characterization of the thyroid proteinase of the burbot, Lota lota L. PMID- 4147938 TI - Death induced by injection stress in cold-acclimated goldfish, Carassius auratus. PMID- 4147939 TI - The effect of imipramine on in vitro dog bladder muscle contractility. PMID- 4147940 TI - Implants and transplants: review of recent research in this area of oral surgery. PMID- 4147941 TI - The effects of pregnancy, lactation and involution on the metabolism of glucose and acetate by rat liver tissue. PMID- 4147942 TI - Beta-Adrenergic blocking agents. Nitrogen heteroaryl-substituted 2-propanolamines and ethanolamines. PMID- 4147943 TI - Item level racial differences on the MMPI. PMID- 4147945 TI - [Enzymatic activities of the granulocytes of the normal man (author's transl)]. PMID- 4147944 TI - The treatment of hemorrhagic shock with WR-149,024 (1,18-diamino-6,13-diaza-9,10 dithiaoctadecane tetrahydrochloride). PMID- 4147946 TI - Lipid peroxidation in spermatozoa. PMID- 4147947 TI - Adenosine 3':5'-cyclic monophosphate in relation to motility and senescence of spermatozoa. PMID- 4147948 TI - Electrogenic sodium pump in pancreatic acinar cells. PMID- 4147949 TI - Spontaneous action potentials in isolated guinea-pig cerebellar slices: effects of amino acids and conditions affecting sodium and water uptake. PMID- 4147950 TI - Inhibition by actinomycin D of the denervation-induced action potential in frog slow muscle fibres. PMID- 4147951 TI - The growth of tumours in T-cell deprived mice and their response to treatment with Corynebacterium parvum. PMID- 4147953 TI - [Inhibition of immunologically induced inflammation by the plant steroid withaferin A]. PMID- 4147952 TI - Proceedings: Study of enzyme induction in epileptic children. PMID- 4147954 TI - [The behavior of male albino mice in the running wheel experiment]. PMID- 4147956 TI - Is phenobarbital a "gratuitous" inducer in male rats? PMID- 4147958 TI - Anticonvulsant effect of 5-ethyl,5-phenyl,2-pyrrolidinone and its possible relationship to gamma-aminobutyric acid-dependent inhibitory mechanisms. PMID- 4147959 TI - The metabolism of palmitic, stearic, oleic and linoleic acids in broiled chickens. PMID- 4147960 TI - The effects of vitamin C on the relationship between leucocyte and plasma ascorbic acid concentrations and the blood glutathione concentration. PMID- 4147961 TI - Welcome address: 48th All-India Medical Conference. PMID- 4147962 TI - Reactivity of arteries to neurohormones in experimental vibration. PMID- 4147963 TI - The younger physician speaks. PMID- 4147964 TI - The winds of change. PMID- 4147965 TI - [Surgery of undescended testis (author's transl)]. PMID- 4147966 TI - Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro. PMID- 4147967 TI - Further evidence for the heterogeneous storage of noradrenaline in central noradrenergic terminals. PMID- 4147969 TI - Pharmacological backgrounds of drug interaction. PMID- 4147968 TI - Central nervous alpha-adrenergic receptors and the mode of action of alpha methyldopa. PMID- 4147970 TI - Masculinity-femininity: an exception to a famous dictum? PMID- 4147971 TI - Preliminary characterization of an inhibitor of drug metabolism released in response to cyclic adenine nucleotides. PMID- 4147972 TI - Induction of hepatic tyrosine aminotransferase by tyrosine-copper(II)-complex. PMID- 4147973 TI - The developmental localization of macromolecular groups in selected stages of Hydractinia echinata. PMID- 4147975 TI - Hereditary influence on the normal personality using the MMPI. II. Prospective assortative mating. PMID- 4147974 TI - Common origin for all neuroendocrine tumors. PMID- 4147976 TI - Multiple forms of glutamine synthetase. Hybrid formation by association of adenylylated and unadenylylated subunits. PMID- 4147977 TI - Mechanism of inactivation of L-glutamate dehydrogenase by pyridoxal and pyridoxal phosphate. PMID- 4147978 TI - Identification of the product excited states during the chemiluminescent and bioluminescent oxidation of Renilla (sea pansy) luciferin and certain of its analogs. PMID- 4147979 TI - Relationships between personality dimensions: neuroticism and extraversion against obsessive, hysterical and oral personality. PMID- 4147980 TI - Comparison of relative inotropic and chronotropic effects of propranolol, practolol, and sotalol. PMID- 4147981 TI - Effects of calcium, isuprel and inderal on the calcitonin content of rat thyroid glands. PMID- 4147982 TI - Reduction of pyridine nucleotides induced by adenosine diphosphate in kidney mitochondria. The influence of sodium, magnesium, and inhibitors of oxidative phosphorylation. PMID- 4147983 TI - Evidence that peroxidation of lysosomal membranes is initiated by hydroxyl free radicals produced during flavin enzyme activity. PMID- 4147984 TI - Full time course studies on the oxidation of reduced coenzyme by bovine liver glutamate dehydrogenase. Use of computer simulation to obtain rate and dissociation constants. PMID- 4147985 TI - Stringent control of fatty acid synthesis in Escherichia coli. Possible regulation of acetyl coenzyme A carboxylase by ppGpp. PMID- 4147986 TI - Effects of splenectomy and beta-adrenoceptor blockade on cardiac output response to acute hypoxemia. AB - Acute hypoxemia produced by the inhalation of 8% and 5% oxygen increased cardiac output in intact anesthetized dogs by 38% and 62%, respectively. Although practolol, a cardioselective beta-adrenergic blocking agent, reduced the increase in cardiac output in dogs subjected to severe hypoxemia (5% O(2) breathing) from 62% to 43%, it only slightly reduced the cardiac output rise in dogs subjected to moderate hypoxemia (8% O(2) breathing). Splenectomy, on the other hand, abolished the increase in cardiac output produced by moderate hypoxemia except for a small initial rise, but it reduced the increase in cardiac output during severe hypoxemia only to 37%. The entire increase, except for a small initial rise, disappeared only when splenectomized dogs were pretreated with practolol. Sham operation did not affect the cardiac output response to hypoxemia. It is concluded that an intact spleen is required for a significant portion of the increased cardiac output that occurs during both moderate and severe hypoxemia and that catecholamines do not participate in the regulation of cardiac output unless severe hypoxemia occurs. PMID- 4147987 TI - Medical education and medical care in underserved rural areas. PMID- 4147988 TI - Health care in rural New Mexico. PMID- 4147989 TI - [Functional treatment of collum humeri fractures in the aged]. PMID- 4147990 TI - [The importance of plastic resections in tumor therapy]. PMID- 4147991 TI - [Juvenile osteochondritis of the lumbar spine]. PMID- 4147992 TI - [Simultaneous injury of thoracic bones and cervical vertebrae]. PMID- 4147993 TI - [Indications for primary prosthesis in femoral neck fractures of the aged]. PMID- 4147994 TI - [Surgical treatment of fresh ligament injuries of the knee and ankle]. PMID- 4147995 TI - [A typical course of traumatic iatrogenic osteomyelitis]. PMID- 4147996 TI - [Surgical treatment of cervical spinal fracture in Bechterew's disease]. PMID- 4147997 TI - [Trauma ex vacuo]. PMID- 4147998 TI - [Diagnostic and therapeutic errors in the management of fresh hand injuries]. PMID- 4147999 TI - Letter: Beta-blocking drugs. PMID- 4148000 TI - Alteration of 5-hydroxytryptamine-14C efflux by nicotine in rat brain area slices. PMID- 4148001 TI - Control of guanylate cyclase activity in the rod outer segment. AB - Mammalian photoreceptors contain a guanylate cyclase which has a high specific activity and is inhibited by exposure of the rod outer segment to light. Several minutes are required for this inhibition to take effect, indicating that it is not a step in visual excitation. The activity of the enzyme is sensitive to the concentration of calcium ion in the medium, suggesting that light-induced changes in calcium distribution in the photoreceptor could control guanylate cyclase activity. PMID- 4148002 TI - [Effect of a combination of vasoactive substances on metabolism and the rheoencephalogram]. PMID- 4148004 TI - Complex formation between magnesium ions and pyridine nucleotide coenzymes. PMID- 4148003 TI - A kinetic assay of TPNH-dependent microsomal lipid peroxidation by changes in difference spectra. PMID- 4148005 TI - Mechanism of enzyme action. VI. Kinetic isotope effect on D-amino acid oxidase reaction. PMID- 4148006 TI - Hyperproduction of dihydrofolate reductase in Diplococcus pneumoniae after mutation in the structural gene. Evidence for an effect at the level of transcription. AB - Dihydrofolate reductase is markedly hyperproduced in strains of Diplococcus pneumoniae which bear any one of a unique group of sense to sense mutations (ame(r)) in the corresponding structural gene. Increased enzyme levels mediated by the ame(r) mutations are apparently the result of increased rates of de novo synthesis. The basis for these effects could be transcriptional, translational or could involve an increase in messenger RNA stability. Data revealing no difference in stability of the related mRNA in a variety of mutants and the wild type strain appear to eliminate the last possibility. Other data support the idea of an effect on transcription. This includes the extreme sensitivity of ame(r) mutation expression following genetic transformation, to inhibition by actinomycin D and rifampacin, and the presence in one extremely high level mutant (ame(r)-3 with 120 times the wild-type enzyme content) of increased amounts of mRNA. The data are most compatible with the idea of a regulatory function for the dihydrofolate reductase protein in this organism. PMID- 4148007 TI - Recognition of streptococcal DNA by a mutant pneumococcus unable to discriminate among markers in pneumococcal DNA. AB - A mutant strain of pneumococcus which fails to discriminate against low efficiency markers during transformation by homospecific pneumococcal donor DNA retains the wild-type capacity to discriminate against heterospecific (streptococcal) donor DNA. We conclude that discrimination against heterospecific DNA must differ from that against low-efficiency markers by the kind or number of elements being recognized. PMID- 4148008 TI - Oxidation of S-carboxymethylcysteine by D-aspartate oxidase. PMID- 4148010 TI - Restricted rabbit antibodies: amino acid sequences of rabbit H chains of allotype a1, a2, and a3 in the region 80 to 94. PMID- 4148009 TI - Studies of biologic and serologic activities of rabbit-IgG antibody depleted of carbohydrate residues. PMID- 4148011 TI - The epileptogenic effects of folate derivatives in the rat. PMID- 4148012 TI - Secular trends in the prevalence of caries. PMID- 4148013 TI - Combined transpyeloureterostomy and ipsilateral pyeloureterostomy and orchiopexy by testicular artery transection: treatment in a case of prune belly syndrome. PMID- 4148014 TI - Letter: Treatment of jellyfish stings. PMID- 4148015 TI - Striatal tyrosine hydroxylases with high and low affinity for tyrosine: implications for the multiple-pool concept of catecholamines. PMID- 4148016 TI - [Treatment possibilities in bromcarbamide poisoning]. PMID- 4148017 TI - [Free and protein-bound corticosteroid fractions in rats during the action of various ulcerogenic factors on the body]. PMID- 4148018 TI - [Blood coagulation changes at various phases in the development of periarteritis nodosa in children]. PMID- 4148019 TI - [DMF and RLM: various results in white children 8 to 12 years old]. PMID- 4148020 TI - Effect of temperature on the mixed function oxidase-catalyzed metabolism of O,O diethyl p-nitrophenyl phosphorothionate (parathion). PMID- 4148021 TI - The effects on canine cardiac Purkinje fibers of Chrysaora quinquecirrha (sea nettle) toxin. PMID- 4148022 TI - The effect of two jellyfish toxins on calcium ion transport. PMID- 4148023 TI - Protective effects of azathioprine and phenobarbital on acute liver damage produced by galactosamine. PMID- 4148024 TI - Mammalian glutamine synthetase: molecular and regulatory properties. PMID- 4148025 TI - The fourth A. J. Kluyver memorial lecture delivered before the Netherlands Society for Microbiology on April 27th, 1972, at the Delft University of Technology, Delft. The halobacteria's confusion to biology. PMID- 4148027 TI - The occurrence of Streptococcus mutans in the dental plaque of a group of Central Australian Aborigines. PMID- 4148026 TI - A theoretical study on the amount of ATP required for synthesis of microbial cell material. PMID- 4148028 TI - The association between dental caries and the availability of sweets in South Australian school canteens. PMID- 4148029 TI - Energy transduction in photosynthetic bacteria. VI. Respiratory sites of energy conservation in membranes from dark-grown cells of Rhodopseudomonas capsulata. PMID- 4148031 TI - [Trimepranol and propranolol (author's transl)]. PMID- 4148030 TI - The isolation and characterization of plasma membranes from normal and leukaemic cells of mice. PMID- 4148032 TI - Cardiospecific beta-adrenergic blockade in the treatment of nervous heart symptoms. PMID- 4148033 TI - [Metabolism of methanol by Candida methylica]. PMID- 4148034 TI - [Isolation of mesosomes from Micrococcus lysodeikticus bacteria]. PMID- 4148035 TI - [Oxidation and NADPH-dependent reduction of intramitochondrial glutathione]. PMID- 4148036 TI - Growth patterns of fetal hemopoiesis and the regulation of fetal erythropoiesis. PMID- 4148037 TI - Clinical evaluation of three concentrations of sodium fluoride in dentifrices. PMID- 4148038 TI - Friend leukemic mouse stem cell reversion to normal growth in irradiated hosts. PMID- 4148040 TI - Nurse of feldsher? A crisis of identity. PMID- 4148039 TI - [Significance of gamma glutamyl transpeptidase activity in clinical diagnosis. II]. PMID- 4148041 TI - Adrenergic receptors: a personal and practical view. PMID- 4148042 TI - [Acute peril of bromine-containing soporifics]. PMID- 4148044 TI - [Diagnostic problems of polymyositis and panarteritis]. PMID- 4148043 TI - [Recent therapeutic developments in the treatment of myocardial infarction]. PMID- 4148045 TI - [Angina pectoris: medical or surgical treatment]. PMID- 4148046 TI - A study of traumatized permanent teeth in children 7-15 years. I. PMID- 4148047 TI - [Functional role of transmitter systems in the brain]. PMID- 4148048 TI - [Nitroglycerin and beta blockers: the only current drugs in angina pectoris. Report of the information booklet from the Swedish Social Governmental Agency "Drugs in angina pectoris" 1971 part 2:I and 2:II]. PMID- 4148049 TI - Gamma-glutamyl transpeptidase in diseases of the liver and bone. PMID- 4148050 TI - Gamma-glutamyl transpeptidase and other liver function tests in myocardial infarction and heart failure. PMID- 4148051 TI - Acute respiratory infections in different ecologic settings. I. Argentine military recruits. PMID- 4148052 TI - Nicotinamide nucleotide coenzymes in mycobacteria. PMID- 4148053 TI - Modification of myocardial infarction size after coronary occlusion. PMID- 4148054 TI - Ediortial: Isoenzymes of creatine phosphokinase and diagnosis of myocardial infarction. PMID- 4148055 TI - Corneal erosions in tyrosinosis. PMID- 4148056 TI - Hypertensive effects of prolonged auditory, visual, and motion stimulation. PMID- 4148057 TI - Experimental studies on overwintering conditions of mosquitoes. PMID- 4148058 TI - Effect of perinatal undernutrition on the metabolism of catecholamines in the rat brain. PMID- 4148059 TI - Effects of dietary protein content and glucagon administration on tyrosine metabolism and tyrosine toxicity in the rat. PMID- 4148060 TI - Metabolism of clindamycin. II. Urinary excretion products of clindamycin in rat and dog. PMID- 4148061 TI - Rift Valley fever. 2. Attempts to transmit virus with seven species of mosquito. PMID- 4148062 TI - Pharmacological findings during azidocillin treatment of chest infections. PMID- 4148063 TI - Broad or narrow spectrum therapy? Studies with ampicillin and azidocillin in acute chest infections. PMID- 4148064 TI - Septicemia in narcotic addicts. PMID- 4148065 TI - [Diffuse pulmonary fibrosis in panarteritis nodosa]. PMID- 4148066 TI - Editorial: Allied health manpower: the physician's associate. PMID- 4148067 TI - [Effect of midodrin on orthostasis]. PMID- 4148068 TI - Cardiovascular haemodynamics during fluroxene anaesthesia in patients with aortic valvular disease. PMID- 4148069 TI - Cardiovascular haemodynamics during fluroxene anaesthesia in patients with muscular subaortic stenosis. PMID- 4148070 TI - The glucose effect in rat liver: studies of delta-aminolevulinate synthase and tyrosine aminotransferase. PMID- 4148071 TI - Activation and blockade of beta adrenoceptors in common cardiac disorders. PMID- 4148072 TI - Cleavage of lens protein-GSH mixed disulfide by glutathione reductase. PMID- 4148073 TI - Immunocompetence in regional graft-versus-host reaction of blood cells from skin allografted or ALS treated rats. PMID- 4148074 TI - The influence of hostsplenectomy on the tumour allograft-promoting effectiveness of antilymphocyte serum. PMID- 4148075 TI - Enzymes involved in phenylalanine metabolism in the human foetus and child. AB - The activities of phenylalanine p-hydroxylase, tyrosine: alpha-ketoglutarate and phenylalanine: pyruvate aminotransferases, and aromatic alpha-ketoacid reductase have been measured in liver biopsies obtained from children with a series of disorders other than phenylketonuria and from human foetuses aged 8.5 to 24 weeks. The importance of such a study in relation to the management of infants with hyperphenylalaninaemia and pregnant phenylketonuric women is discussed PMID- 4148077 TI - A comparative study of flight performance and fuel utilization as a function of age in females of Florida mosquitoes. PMID- 4148076 TI - Serum D-glutamyl transferase following myocardial infarction. AB - D-glutamyl transferase (GMT) activity was measured in 49 patients with proven myocardial infarction. Twenty-three patients had normal GMT activity and 26 had increased GMT activity. Most of the patients with increased GMT had evidence of liver dysfunction and it is suggested that any increases in serum GMT activity following myocardial infarction are a result of secondary liver damage rather than a release of GMT from cardiac tissue. PMID- 4148078 TI - Current therapy for undescended testicle. Rationale for treatment between ages four and five. PMID- 4148080 TI - [Treatment of the hypertensive crisis]. PMID- 4148079 TI - Inflammatory bowel disease in the adolescent patient. PMID- 4148081 TI - [Production, isolation and characterization of a physiological sleep factor "delta"]. PMID- 4148082 TI - [Beta-blockers, beta-stimulators and Raymaud's syndrome]. PMID- 4148083 TI - Agglutinins from fish ova defining blood groups B and P. PMID- 4148084 TI - [Diabetes mellitus as complication from periarteritis nodosa]. PMID- 4148085 TI - [Antigonadotropins and gonadotropins in some endocrine disorders of the male genitalia]. PMID- 4148086 TI - The effects of centrophenoxine and palmitoylethanolamide on the social behavior of rats malnourished in early postnatal life. PMID- 4148087 TI - [Conclusions concerning the problem of psychosomatic fatique during lithium maintenance therapy]. PMID- 4148088 TI - Psychiatric pharmacotherapy and the schizophrenic defect. PMID- 4148089 TI - The effect of amantadine on neuroleptic-induced parkinsonism. PMID- 4148090 TI - [Clinical resemblance of Oppenheim's contact dermatitis and dermatitis produced by contact with marine algae impregnated with urticating cells of Physalia arethusia]. PMID- 4148091 TI - Influence of progestational steroids on hypothalamic tyrosine hydroxylase activity in vitro. PMID- 4148092 TI - Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the immune system of laboratory animals. PMID- 4148094 TI - Summary: conference on dibenzodioxins and dibenzofurans, National Institute of Environmental Health Services, April 2-3, 1973. PMID- 4148093 TI - TCDD-induced changes in rat liver microsomal enzymes. PMID- 4148095 TI - Integration efficiencies of spontaneous mutant alleles of amiA locus in pneumococcal transformation. AB - The distribution of integration efficiencies of independent mutations spontaneously occurring in the amiA locus was determined in two strains of pneumococcus. Strain Cl(3) integrates genetic markers with different efficiencies during transformation, whereas strain 401, isogenic with strain Cl(3), does not discriminate between markers and integrates all markers with the same high efficiency. The discriminating strain Cl(3) gives rise to spontaneous mutations in the locus amiA, which fall into four classes with respect to their individual integration efficiencies. Mutations with a low efficiency of integration are equal in number to mutations with a high efficiency. Mutations from the two other classes corresponding to intermediate and very high efficiencies are about five times less frequent. The same four classes were also found among amiA mutants spontaneously occurring in strain 401. However, the two distributions of integration efficiencies of amiA mutants arisen either in strain Cl(3) or strain 401 are significantly different. The number of spontaneous amiA mutants, estimated by two methods, was found to be higher in strain 401 than in strain Cl(3). The increase of the mutation rate in strain 401 could be accounted for by the excess of mutations falling in the two less-efficient classes observed in this strain. The discriminating process which acts during transformation presumably also intervenes in the appearance of spontaneous mutations. PMID- 4148096 TI - Purification and regulation of glucose-6-phosphate dehydrogenase from Bacillus licheniformis. AB - d-Glucose-6-phosphate nicotinamide adenine dinucleotide phosphate (NADP) oxidoreductase (EC 1.1.1.49) from Bacillus licheniformis has been purified approximately 600-fold. The enzyme appears to be constitutive and exhibits activity with either oxidized NAD (NAD(+)) or oxidized NADP (NADP(+)) as electron acceptor. The enzyme has a pH optimum of 9.0 and has an absolute requirement for cations, either monovalent or divalent. The enzyme exhibits a K(m) of approximately 5 muM for NADP(+), 3 mM for NAD(+), and 0.2 mM for glucose-6 phosphate. Reduced NADP (NADPH) is a competitive inhibitor with respect to NADP(+) (K(m) = 10 muM). Phosphoenolpyruvate (K(m) = 1.6 mM), adenosine 5' triphosphate (K(m) = 0.5 mM), adenosine diphosphate (K(m) = 1.5 mM), and adenosine 5'-monophosphate (K(m) = 3.0 mM) are competitive inhibitors with respect to NAD(+). The molecular weight as estimated from sucrose density centrifugation and molecular sieve chromatography is 1.1 x 10(5). Sodium dodecyl sulfate gel electrophoresis indicates that the enzyme is composed of two similar subunits of approximately 6 x 10(4) molecular weight. The intracellular levels of glucose-6-phosphate, NAD(+), and NADP(+) were measured and found to be approximately 1 mM, 0.9 mM, and 0.2 mM, respectively, during logarithmic growth. From a consideration of the substrate pool sizes and types of inhibitors, we conclude that this single constitutive enzyme may function in two roles in the cell-NADH production for energetics and NADPH production for reductive biosynthesis. PMID- 4148097 TI - Catabolism of D-gluaric acid to alpha-ketoglutarate in Bacillus megaterium. AB - Crude cell-free extracts of d-glucarate-grown cells of Bacillus megaterium converted d-glucarate to alpha-keto-beta-deoxy-d-glucarate (KDG). Charcoal treated cell-free extracts or partially purified enzyme preparations converted KDG to an intermediate which was isolated and identified as 2,5-diketoadipate (DKA). This compound was synthesized, and the cell-free extracts of d-glucarate grown cells were found to catalyze the reduction of nicotinamide adenine dinucleotide (NAD) in its presence. In the absence of NAD, the same enzyme preparation catalyzed the decarboxylation of the DKA to alpha-ketoglutarate semialdehyde (KGS), whereas in the presence of NAD the KGS was subsequently oxidized to alpha-ketoglutarate by alpha-ketoglutarate semialdehyde dehydrogenase. Since galactarate-grown B. megaterium contains a galactarate dehydrase forming KDG, the complete pathway for the metabolism of d-glucarate or galactarate to alpha-ketoglutarate and CO(2) is now known in a gram-positive bacterium. PMID- 4148099 TI - Multiple sites for coupling of glucose transport to the respiratory chain of membrane vesicles from Azotobacter vinelandii. PMID- 4148098 TI - Inhibition studies of rat citrate synthase. PMID- 4148100 TI - A glutamyl residue in the active site of triphosphopyridine nucleotide-dependent isocitrate dehydrogenase of pig heart. PMID- 4148102 TI - Triage, technicians, and teaching in a children's emergency room. PMID- 4148103 TI - The effect of abnormal position, scrotal repositioning, and human gonadotropic hormone on the developing puppy testis. PMID- 4148101 TI - Electron transport components of hepatic microsomes. Solubilization, resolution, and recombination to reconstitute aniline hydroxylase activity. PMID- 4148104 TI - Letter: Hemolytic anemia as adverse reaction to salicylazosulfapyridine. PMID- 4148105 TI - The stimulation of lipid peroxidation produced by dimethylnitrosamine in rat liver microsomes in vitro: the effects of promethazine and inhibitors of drug metabolism, and a comparison with previous studies using carbon tetrachloride. PMID- 4148106 TI - Interference of the reduction of p-nitrobenzoate in E. coli by nitrofurantoin. PMID- 4148107 TI - Chemical respirogenesis: a comparative study. PMID- 4148108 TI - Effects of beta-blocking agents on atrio-ventricular and intraventricular conduction in man. PMID- 4148109 TI - Double-blind trial of doxicycline in acute maxillary sinusitis. A clinical and bacteriological study. PMID- 4148110 TI - Genetic classification and biological properties of temperature-sensitive mutants of fowl plague virus. PMID- 4148111 TI - Study on the mutagenic action of O-methylhydroxylamine on RNA viruses (on the model of fowl plague virus). PMID- 4148113 TI - Behaviour of attenuated mutants of the A0-NWS influenza virus in mice after intracerebral inoculation. I. Induction of resistance to challenge with neurotropic A0-NWS virus. PMID- 4148112 TI - Investigations on the dynamics of the reaction between tick-borne encephalitis virus and its specific receptor substance. PMID- 4148114 TI - Serum immunoglobulins in white rats immunized with foot-and-mouth disease virus antigens. PMID- 4148115 TI - Analysis of Sindbis virus and its soluble antigens in preparations concentrated by precipitation with polyethylene glycol or ammonium sulfate. PMID- 4148116 TI - Rickettsial toxin and its specificity in 3 prototype strains, Karp, Gilliam and Kato, of Rickettsia orientalis. PMID- 4148117 TI - Interferon production and infection caused by influenza virus in radiation chimeras. PMID- 4148118 TI - Multiplication of parainfluenza type 1 virus in chick embryos. PMID- 4148119 TI - Blackbird, Turdus merula L., and tick-borne encephalitis (TBE) virus. PMID- 4148120 TI - DNA composition in Rickettsia mooseri by base analysis. PMID- 4148121 TI - Olkya--an arbovirus of the Bunyamwera group in the U.S.S.R. PMID- 4148122 TI - In vitro evidence for a cell-mediated component of the immune response in mice given the highly attenuated E5 "14" Langat virus (the tick-borne encephalitis complex). PMID- 4148123 TI - The use of receptor destroying enzyme for removing non-specific serum inhibitors against recent influenza virus strains. PMID- 4148124 TI - View of human problems to be addressed for long-duration space flights. PMID- 4148125 TI - [Hepatic granulomas]. PMID- 4148126 TI - 12alpha-hydroxylation of 7alpha-hydroxy-4-cholesten-3-one by a reconstituted system from rat liver microsomes. PMID- 4148127 TI - Activity of horse liver alcohol dehydrogenase SS with NADP (H) as coenzyme and its sensitivity to barbiturates. PMID- 4148128 TI - Cross-linking of salmon fibrinogen and fibrin by factor XIII and transglutaminase. PMID- 4148129 TI - The use of the oxidant"diamide" for studying the non-mitochondrial reducing capacity of Ehrlich ascites tumor cells. PMID- 4148130 TI - Fluorescent labeling of proteins. A new methodology. PMID- 4148131 TI - Possible control of hydrogen peroxide production and degradation in microsomes during mixed function oxidation reaction. PMID- 4148132 TI - Cytoplasmic binding of dexamethasone and induction of tyrosine aminotransferase in neonatal rat liver. PMID- 4148133 TI - Editorial: World Medical Association. PMID- 4148134 TI - Biochemical effects of oxygen at high pressure in rats. PMID- 4148136 TI - Histochemical localization of delta 5-3 beta-hydroxysteroid dehydrogenase and glucose-6-phosphate dehydrogenase in the testis of Indian skipper frog Rana cyanophlyctis (Schneider). PMID- 4148135 TI - Anti-inflammatory drug mechanisms. PMID- 4148137 TI - A neurohormone of cephalopods with cardioexcitatory activity. PMID- 4148138 TI - Adrenergic antagonists, and a possible link between the increase in cyclic adenosine 3',5'-monophosphate and DNA synthesis during liver regeneration. PMID- 4148140 TI - Effect of gonadotropins in the induction of spermatogenesis in human prepubertal testis. PMID- 4148139 TI - Pyridine nucleotide metabolism in mammalian cells in culture. PMID- 4148141 TI - Use of LB-46, a new anti-arrhythmic agent, during anesthesia. PMID- 4148142 TI - [Significance of gamma-glutamyl transpeptidase activity in clinical diagnosis]. PMID- 4148143 TI - The influence of ethanol administered to pregnant rats on tyrosine hydroxylase activity of their offspring. PMID- 4148144 TI - [Therapy of testicular dystopia, obstruction of efferent ejaculatory ducts and of varicocele from the andrological viewpoint]. PMID- 4148146 TI - The impairment of graft-versus-host reaction by immunisation of F1 hybrids with low doses of parental cells. PMID- 4148145 TI - Inhibition of graft-versus-host reaction by preincubation of the graft with a thymic extract (lymphocyte chalone). PMID- 4148147 TI - The graft-versus-host reaction in the snapping turtle Chelydra serpentina. PMID- 4148148 TI - [The effect of a spleen dialysate on the rat testis (author's transl)]. PMID- 4148149 TI - [The LH and FSH output in artificial cryptorchidism (author's transl)]. PMID- 4148150 TI - [Action mechanism of an antihistaminic on specific automobile driving capacities and their influencing through packaging]. PMID- 4148152 TI - [International Surgical Association]. PMID- 4148151 TI - [The disastrous end of "Operation Monchweiler"]. PMID- 4148153 TI - Hyposplenism and pneumococcemia. Visualization of Diplococcus pneumoniae in the peripheral blood smear. PMID- 4148154 TI - Fluorescence and phosphorescence of antihistamines having the 2-aminopyridine chromophore. Effect of pH on fluorescence. PMID- 4148155 TI - Control of the microsomal mixed-function oxidase by Ox2 and Ox5 genes in houseflies. PMID- 4148156 TI - Metabolic properties of erythrocytes of normal and genetically anemic mice. PMID- 4148157 TI - Pharmacological prevention of acute ventilatory capacity reduction in flax dust exposure. PMID- 4148158 TI - Adaptation of the tiger salamander, Ambystoma tigrinum, to arid habitats. PMID- 4148160 TI - Effects of hypophysectomy and environmental salts on intestinal alkaline phosphatase of the eel in relation to sea water adaptation. PMID- 4148159 TI - Role of alkaline phosphatase in intestinal water absorption by eels adapted to sea water. PMID- 4148161 TI - Ventilation in two species of lizards during rest and activity. PMID- 4148162 TI - Blood physiology and oxygen transport during activity in two lizards, Varanus gouldii and Sauromalus hispidus. PMID- 4148163 TI - The structure, composition and elastic properties of the teleost bulbus arteriosus in the carp, Cyprinus carpio. PMID- 4148164 TI - Induction of bioluminescence in a luciferin deficient form of the marine teleost, Porichthys, in response to exogenous luciferin. PMID- 4148165 TI - Effects of acclimation on oxygen consumption (QO2) of the brain and its different areas in two genera of anurans. PMID- 4148166 TI - Water intake and activity of rodents and Leiothrix lutea under continuous light. PMID- 4148167 TI - Cardiac and respiratory responses of rainbow trout, bluegills and brown bullhead catfish during rapid hypoxia and recovery under normoxic conditions. PMID- 4148168 TI - Heat measurements associated with isometric contraction in fast and slow muscles of the chicken. PMID- 4148169 TI - Panting thresholds of lizards. I. Some methodological and internal influences on the panting threshold of an agamid, Amphibolurus muricatus. PMID- 4148170 TI - Panting thresholds of lizards. II. Diel variation in the panting threshold of Amphibolurus muricatus. PMID- 4148171 TI - Erratum: Relaxation of catch in a molluscan smooth muscle. II. Effects of serotonin, dopamine and related compounds. PMID- 4148172 TI - Effects of ethidium bromide on various segments of the respiratory chain in the cellular slime mold, Dictyostelium discoideum. PMID- 4148173 TI - Animal models for biomedical research. V. Invertebrates. Introduction. PMID- 4148174 TI - Phylogeny of immune responsiveness: marine invertebrates. PMID- 4148176 TI - Basic principles in the use of antipsychotic agents. PMID- 4148175 TI - [Studies of the significance of the electrocardiographic changes produced by orthostatism in patients with neurocirculatory asthenia]. PMID- 4148177 TI - Editorials: malpractice in the 14th century. PMID- 4148179 TI - Radiologist Francis E. Bihss, M.D., honored. PMID- 4148178 TI - EKG of the month. PMID- 4148180 TI - Gastric leiomyoma. PMID- 4148181 TI - Population variation among alcoholism treatment facilities. PMID- 4148182 TI - The Haight-Ashbury drug-using subculture and the MMPI psychopathic scale. PMID- 4148183 TI - The presence and the influence of germination on the gamma-aminobutyrate pathway in Lupinus albus seeds. PMID- 4148184 TI - [Treatment of sympathoganglionitis and gangliosolar plexitis]. PMID- 4148185 TI - Halothane-induced lipolysis in rats. PMID- 4148186 TI - Granulomatous aortitis associated with necrotizing angiitis and glomerulonephritis. PMID- 4148187 TI - Studies on cytoplasmic membrane fractions from guinea pig pancreas. PMID- 4148188 TI - Subcellular localization of neurotransmitters. PMID- 4148189 TI - Subcellular organization of the median eminence. PMID- 4148191 TI - Structure-function relationships in inhibitory synapses. PMID- 4148190 TI - Effect of drugs on adrenergic nerve terminals. PMID- 4148192 TI - Cellular and molecular aspects of transmitter release: calcium monoamine dynamics. PMID- 4148193 TI - A role for the pyridine nitrogen of reduced triphosphopyridinenucleotide in an enzymatic catalysis. PMID- 4148194 TI - On the interaction of para-hydroxybenzoate hydroxylase from Pseudomonas fluorescens with halogen ions. PMID- 4148195 TI - The glucose dehydrogenase activity of the NAD-linked glucose-6-phosphate dehydrogenase from Acetobacter xylinum. PMID- 4148196 TI - [Serum gamma glutamyltranspeptidase in hepatic and biliary diseases]. PMID- 4148197 TI - Test-taking sets and the performance of schizophrenics on laboratory tests. PMID- 4148198 TI - [Mega-ureter and aplasia of the erectile bodies (author's transl)]. PMID- 4148199 TI - [Arterial hypertension in the course of the 1st 3 months following renal transplantation]. PMID- 4148200 TI - [Wunderlich's disease in the course of periarteritis nodosa]. PMID- 4148202 TI - [Virus-like inclusion structures in renal tubular endothelium]. PMID- 4148201 TI - Extraction from bovine spleen of immunosuppressant with no activity on hematopoietic spleen colony formation. PMID- 4148203 TI - Editorial: Leprosy vectors. PMID- 4148204 TI - [Current treatment of acne]. PMID- 4148205 TI - Study on the mechanism of inhibiting action of aminoadamantane on the reproduction of fowl plague virus. PMID- 4148206 TI - Temperature optima of neuraminidase activity of influenza viruses. PMID- 4148207 TI - Development of antibodies to neuraminidase of A2-Hong Kong and A2-Taiwan influenza viruses after administration of different Hong Kong vaccines and after natural infection in humans. PMID- 4148208 TI - Experimental studies on influenza A2 virus infection after peroral inoculation. PMID- 4148209 TI - Resistance of mice immunized per os with A2 influenza virus to intranasal challenge with a pathogenic strain. PMID- 4148210 TI - Cultivation of ganglia on monofil fabric, a suitable method for demonstration of latent herpesvirus infection. PMID- 4148211 TI - Use of proflavine-sensitized poliovirus strains for determination of the range of susceptible animals. PMID- 4148212 TI - Formation of autoantibodies in laboratory animals after inoculation of viruses with different virulence. I. Results of studies on vaccine and wild strains of polio and measles viruses in guinea pigs. PMID- 4148213 TI - Viral infection and resistance in immunosuppressed host. IV. Abolition of potentiated togavirus A infection by a resistance inducer of the double-stranded RNA type. Failure of an exogenous interferon preparation. PMID- 4148214 TI - Transmission of Kyasanur Forest disease virus by the soft tick, Ornithodoros crossi. PMID- 4148215 TI - Studies on antigenic peculiarities of West Nile virus strains isolated in the U.S.S.R. by three serological tests. PMID- 4148216 TI - Investigations on rhinovirus inactivation by hydrogen peroxide. PMID- 4148217 TI - Effect of protein synthesis inhibitors on the replication of virus-induced RNA in Sendai virus-infected cells. PMID- 4148218 TI - Isolation of Sindbis virus from the reed warbler (Acrocephalus scirpaceus) in Slovakia. PMID- 4148219 TI - Role of the temperature of incubation of infected chick embryos in the differentiation of certain poxviruses according to pock morphology. PMID- 4148220 TI - Isolations of coxsackie viruses from Danube river water. PMID- 4148221 TI - Sequential fluorescent antibody staining for the demonstration of double infection with tick-borne encephalitis and herpes simplex viruses in chick embryo cell cultures. PMID- 4148222 TI - Studies on the mutagenic action of proflavine on type 3 poliovirus. PMID- 4148223 TI - Changes in some genetic markers of measles virus strain L-16 in the course of passaging in various cell cultures. PMID- 4148224 TI - Humoral antibody response in volunteers given the live, highly attenuated "14" clone derived from Langat E5 virus. PMID- 4148225 TI - HUD's role in the interagency action in nutrition and aging. PMID- 4148226 TI - Phases of psychopathology after assassination. PMID- 4148227 TI - Letter: Marijuana flashbacks. PMID- 4148228 TI - The histochemistry of prefascial lymph vessels in recurrent erysipelas. PMID- 4148229 TI - Microsomal-catalyzed hydroperoxide-dependent C-oxidation of amines. PMID- 4148230 TI - Transcriptional and translational control of the biphasic increase in ornithine decarboxylase activity in liver. PMID- 4148231 TI - On the role of superoxide in reactions catalyzed by rubredoxin of Pseudomonas oleovorans. PMID- 4148232 TI - The temperature dependence of oxidative phosphorylation and of the activity of various enzyme systems in liver mitochondria from cold- and warm-blooded animals. PMID- 4148233 TI - Studies on immunological paralysis. XI. A comparison of the tolerogenicity in vitro of levan and type 3 pneumococcal polysaccharide. PMID- 4148234 TI - Development of host plasma cells during graft-versus-host reactions in mice. PMID- 4148235 TI - Density gradient separation of chicken thymus cells. PMID- 4148236 TI - The many facets of cardiac pathology. PMID- 4148237 TI - D-aspartate oxidase in mammalian brain and choroid plexus. PMID- 4148238 TI - Tyrosine hydroxylase of sheep brain: some catalytic and chemical properties of the detergent-solubilized, partially purified enzyme. PMID- 4148239 TI - The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain. PMID- 4148240 TI - Partial purification and characterization of NADPH-linked aldehyde reductase from monkey brain. PMID- 4148242 TI - Influence of potassium on the steady-state redox potential of the electron transport chain in slices of rat cerebral cortex and the effect of ouabain. PMID- 4148241 TI - Early changes in respiration, aerobic glycolysis and cellular NAD(P)H in slices of rat cerebral cortex exposed to elevated concentrations of potassium. PMID- 4148243 TI - On the association of non-specific esterase activity with central nerve myelin preparations. PMID- 4148244 TI - [Alternating psychotic episodes in impulsive petit mal]. PMID- 4148245 TI - [Pathological and anatomical contribution to pulmonic purulent leptomeningitis and pulmonic brain abscess]. PMID- 4148246 TI - [Possibilities of differential treatment of the chronic form of ischemic heart disease]. PMID- 4148247 TI - [Severe complications after administration of pypolfen]. PMID- 4148248 TI - Partial purification of a toxin from tentacles of the sea anemone Anemonia sulcata. PMID- 4148249 TI - An in vivo test for the immunocompetence of human lymphocytes. PMID- 4148250 TI - Specific inactivation of cytotoxic lymphocytes after adsorption on 51Cr-labeled fibroblast monolayers. PMID- 4148251 TI - [Neuro-humoral changes in transitory disorders of the cerebral blood circulation]. PMID- 4148252 TI - [Metabolism of lipids, blood anticoagulation system and neurohumoral regulation in collagenoses]. PMID- 4148253 TI - [Effect of Trazikor on external respiration indices in patients with stenocardia]. PMID- 4148254 TI - [Comparative studies on personality variations in failures in autogenic training with the aid of the MMPI]. PMID- 4148255 TI - Non-random frequency distributions of caries attacks among mesial and distal surfaces of human permanent mandibular incisors. PMID- 4148256 TI - The estimation of examiner error and the true transition probabilities for teeth or surfaces in dental clinical trials. PMID- 4148257 TI - Editorial: Intermediate coronary syndrome. PMID- 4148258 TI - The fear of heights among alcoholics. PMID- 4148259 TI - [Unusual clinical manifestations in the course of arbovirus infections]. PMID- 4148260 TI - [Proceedings and conclusion of the 26th World Health Assembly]. PMID- 4148261 TI - [Multiple endocrine adenomatosis]. PMID- 4148262 TI - [Treatment of periarteritis nodosa using immunosuppressants and glucocorticoids]. PMID- 4148263 TI - Detailed studies on the in vitro antimicrobial activity of antazoline hydrochloride. PMID- 4148264 TI - [Some mechanisms of the pathogenesis of experimental stomach ulcer]. PMID- 4148266 TI - [Gamma-glutamyl transpeptidase: general concepts. Cytotopy. Methods. Diagnostic significance]. PMID- 4148265 TI - [Treatment of scleroderma]. PMID- 4148267 TI - [Clinical studies on overlap syndrome]. PMID- 4148268 TI - [Artificial abortion in sheep for the purpose of obtaining karakul lambs]. PMID- 4148269 TI - II. Medical treatment of inflammatory bowel disease. PMID- 4148270 TI - [Cryptorchism as a cause of ileus]. PMID- 4148271 TI - A rapid screening procedure for drug and alcohol analysis in serum. PMID- 4148272 TI - Metabolic, ultrastructural, and mechanical changes in the isolated rat heart perfused with aerobic medium in the absence or presence of glucose. PMID- 4148273 TI - Enzyme changes in experimental biliary obstruction. PMID- 4148274 TI - [Mortality causes in major life insurance]. PMID- 4148275 TI - [Prognosis of obesity]. PMID- 4148276 TI - [Modern ECG diagnosis]. PMID- 4148277 TI - [Side effects of hypotensive drugs and their therapy]. PMID- 4148278 TI - [Sider effects of immunosuppressive therapy]. PMID- 4148279 TI - A note to identify a certain isolate of Lagenidium which kills mosquito larvae. PMID- 4148280 TI - 3. Physical characteristics of Yemenite and Kurdish Jews in Israel. PMID- 4148281 TI - IV. Spirometric studies of Yemenite and Kurdish Jews in Israel. PMID- 4148282 TI - V. Food intake of Yemenite and Kurdish Jews in Israel. PMID- 4148283 TI - VI. Energy expenditure and climatic exposure of Yemenite and Kurdish Jews in Israel. PMID- 4148284 TI - VII. The physical working capacity of Yemenite and Kurdish Jews in Israel. PMID- 4148285 TI - 8. A study of temperature regulation in Yemenite and Kurdish Jews in Israel. PMID- 4148287 TI - X. Haemoglobin studies of Yemenite and Kurdish Jews in Israel. PMID- 4148286 TI - IX. The hereditary blood factors of the Yemenite and Kurdish Jews. PMID- 4148288 TI - XI. The hereditary blood factors of the Kurds of Iran. PMID- 4148289 TI - XII. Genetic studies in Jordan. PMID- 4148290 TI - Biological studies of Yemenite and Kurdish Jews in Israel and other groups in southwest Asia. 18. Conclusions and summary. PMID- 4148291 TI - Biological studies of Yemenite and Kurdish Jews in Israel and other groups in southwest Asia. I. Introduction, background and methods. PMID- 4148292 TI - II. A clinical survey of Yemenite and Kurdish Jews in Israel. PMID- 4148293 TI - [100th anniversary of the 1st Congress of Zemstvo Physicians of the Bessarabian Province (1873)]. PMID- 4148294 TI - [Use of beta-receptor blocking agents in the treatment of arterial hypertension]. PMID- 4148296 TI - [Anesthesiological relief in labor in late pregnancy toxicosis]. PMID- 4148295 TI - [Penbutolol--a sinistrorotatory adrenergic beta-receptor blocking agent. Ergometer investigations in patients with angina pectoris]. PMID- 4148297 TI - [Morphological changes in the liver in periarteritis nodosa]. PMID- 4148298 TI - [Metabolism of oxaflumazine]. PMID- 4148299 TI - Non-nicotinic transmission during ganglionic block with chlorisondamine and nicotine. PMID- 4148300 TI - [Beta adrenergic blocking drugs]. PMID- 4148301 TI - The determination of D- and L-14C-amino acids in the presence of their metabolites. PMID- 4148302 TI - NAD and NADP l-glutamate dehydrogenase activity and ammonium regulation in Aspergillus nidulans. PMID- 4148303 TI - The distribution of NAD-independent lactic dehydrogenases amongst micro organisms. PMID- 4148304 TI - Salt losing nephritis in the prune belly syndrome. PMID- 4148305 TI - [Content of carbon monoxide in expired air and carboxyhemoglobin in the blood of test subjects situated in conditions of sealed protective equipment]. PMID- 4148306 TI - [Treatment of cardiac complications in hyperthyroidism]. PMID- 4148307 TI - [Contribution of scientists of the fraternal republics to the development of clinical gastroenterology]. PMID- 4148308 TI - [Neurologic syndromes in the clinical picture of periarteritis nodosa in children]. PMID- 4148309 TI - [The beta-blocking agents. Their use in cardiology]. PMID- 4148310 TI - [The normal and disturbed prepuberal development of the human testis]. PMID- 4148311 TI - The health care scene: nursing's dilemma. PMID- 4148312 TI - The gas chromatographic determination of anticonvulsant drugs in serum. PMID- 4148313 TI - A history of water fluoridation. Dental caries prevalence in artificially fluoridated areas. PMID- 4148314 TI - Central depressant effects of the extracts of magnolia cortex. PMID- 4148315 TI - [Proceedings: German Roentgen Congress 1972. Abstracts of the 53d session of the German Roentgen Society for Medical Radiology, Radiobiology and Nuclear Medicine Inc., May 11-13, 1972 at Stuttgart]. PMID- 4148316 TI - Lasting effects of early nutrition. PMID- 4148318 TI - The changing face of health care delivery. PMID- 4148319 TI - Neighborhood health centers and model cities. Adjust your practice to their needs? The health care of model cities. PMID- 4148317 TI - Surgical grand rounds: Thymoma with myasthenia. PMID- 4148320 TI - The changing face of health care delivery. Neighborhood health centers and model cities. Adjust your practice to their needs? PMID- 4148321 TI - 15 HMO's in Illinois. How will they affect your practice? The Carbondale "experiment". PMID- 4148322 TI - The changing face of health care delivery. Fifteen HMO's in Illinois. How will they affect your practice? Intergroup: prepaid health services plan. PMID- 4148323 TI - Group practice in Lincoln and a HMO. PMID- 4148324 TI - New hope for over-worked doctors and medically deprived areas. General medical services LTD. Physicians-on-call. PMID- 4148325 TI - The renaissance of the house call. PMID- 4148327 TI - The changing face of health care delivery. Comprehensive Medical Associates. PMID- 4148326 TI - Contract emergency service system. PMID- 4148328 TI - Status report: Illinois statewide trauma care system. PMID- 4148329 TI - Heart to head circulation time. PMID- 4148330 TI - Members of the 1972 House of Delegates. PMID- 4148331 TI - Surgical grand rounds: Adrenal cyst. PMID- 4148332 TI - Editorial: The treatment of gonorrhea in the female. PMID- 4148333 TI - Follow it up. The unpaid bill. PMID- 4148334 TI - The management of penetrating wounds of the abdomen with simultaneous bowel and vascular injuries. PMID- 4148335 TI - L. T. Fruin, M.D.--in memorian. PMID- 4148336 TI - Editorial: "Turf" and Illinois' new medical schools. PMID- 4148337 TI - Ulcerative colitis. Selected clinical, diagnostic and therapeutic aspects. PMID- 4148339 TI - Choosing the safest ski binding. PMID- 4148338 TI - Surgical grand rounds: Ectopic pregnancy. PMID- 4148340 TI - Maternal death study. Case report no. 1. The first in a series of case reports. PMID- 4148341 TI - Comparative study of myfadol and meperidine as postoperative analgesics. PMID- 4148342 TI - The value of the investment counselor. PMID- 4148343 TI - What "health care crisis"? PMID- 4148344 TI - Surgical grand rounds: Pancreatic transplantation. PMID- 4148345 TI - Measles in previously vaccinated children in Illinois. PMID- 4148346 TI - Management of abdominal trauma in children. PMID- 4148347 TI - Maternal death study. Case report no. 2. The second in a series of case reports. PMID- 4148348 TI - Report of a case. Retroperitoneal and gluteal cystic lymphangioma. PMID- 4148349 TI - Prenatal hormones and human behavior. PMID- 4148350 TI - Car restraint devices designed for children. PMID- 4148351 TI - Editorial: Sudden death--premonition of things to come. PMID- 4148352 TI - Letter: ISMS where do you stand on abortion? PMID- 4148353 TI - Will your records satisfy the "tax man"? PMID- 4148354 TI - He who stands and waits. PMID- 4148355 TI - Earlier and better eye care for children. PMID- 4148356 TI - Skin manifestations of hypovitaminosis A. PMID- 4148357 TI - Bicycle spoke injuries. A report of 64 cases. PMID- 4148358 TI - Surgical grand rounds: resection of myocardial infarct. PMID- 4148359 TI - Maternal death study. Case report no. 3. The third in a series of case reports. PMID- 4148360 TI - Chicago Symphony Orchestra--touring Europe. PMID- 4148361 TI - Initial care of critically injured. PMID- 4148362 TI - Editorial: AHA competes with AMA in health care. PMID- 4148363 TI - Autos to lease or not to lease. PMID- 4148364 TI - Hypothyroidism. PMID- 4148365 TI - Controlling allergic parotitis from foods. PMID- 4148366 TI - Autopsy ruling threatens progressive medicine. PMID- 4148367 TI - Sexual pressures in the society. PMID- 4148368 TI - Fluid therapy in hemorrhagic shock. PMID- 4148369 TI - Surgical grand rounds: Submaxillary gland cylindroma. PMID- 4148370 TI - Autotransplantation of splenic tissue. Report of a case. PMID- 4148371 TI - Maternal death study. Case report no. 4. The fourth in a series of case reports. PMID- 4148372 TI - "How to fire an aide gracefully". PMID- 4148373 TI - Letter: Treatment of hypertension with drugs can be dangerous. PMID- 4148375 TI - Report suspected child abuse. PMID- 4148374 TI - Changes in nitroglycerin tablet packaging and labeling. PMID- 4148376 TI - Electron transfer mechanism involved in stearoyl-coenzyme A desaturation by particulate fraction of Mycobacterium phlei. PMID- 4148377 TI - A study of the equilibrium between the monomer and the dimer of D-amino-acid oxidase. PMID- 4148378 TI - Effect of penicillamine (a vitamin B6 antagonist) on pyridoxal enzymes. PMID- 4148379 TI - Structural abnormalities in the undescended testis. PMID- 4148380 TI - Torsion of an intraabdominal testicle in a neonate. PMID- 4148381 TI - Analysis of mode of action of some nicotinic blocking drugs. PMID- 4148382 TI - Enhancement of Ca-contractions by catecholamines and temperature dependency in the depolarized teania coli of the guinea-pig. PMID- 4148383 TI - The possible role of adenosine triphosphate in chemical transmission between the hypogastric nerve terminal and seminal vesicle in the guinea-pig. PMID- 4148384 TI - Pharmacology of dl-5-methyl-8-(2-hydroxy-3-t-butylaminopropoxy) coumarin hydrochloride (CS-359), a new beta-adrenergic blocking agent. PMID- 4148385 TI - Adrenergic receptors in rat liver. I. Effects of epinephrine and adrenergic blocking agents on gluconeogenesis in perfused liver. PMID- 4148386 TI - Electrophysiological evidence of the initiation of arrhythmia by beta-adrenergic blocking agents. PMID- 4148387 TI - Quantitative studies of adrenoceptors in guinea-pig gallbladders. PMID- 4148388 TI - [Round table conference held at the scientific meeting of the Polish Cardiological Society in Warsaw, December 9, 1972]. PMID- 4148389 TI - Automatic refraction: how it is done: some clinical results. PMID- 4148390 TI - [Sulfamethoxazole-trimethoprim and ampicillin in the treatment of bronchitis]. PMID- 4148391 TI - [Problems of species in parasitology. Recapitulation]. PMID- 4148392 TI - [Prevention of premature labor]. PMID- 4148393 TI - [Study of cnidom and cnidogenesis in Apolemia uvaria (Lesueur, 1811) (Siphonophora physonecta)]. PMID- 4148394 TI - The Noonan syndrome--a review of the clinical and genetic features of 27 cases. PMID- 4148395 TI - Why do sputum cultures fail to yield pathogens? PMID- 4148396 TI - [Significance of gamma-glutamyl-transpeptidase activity in the clinical diagnosis]. PMID- 4148397 TI - Presence of glutamate synthase in fission yeasts and its possible role in ammonia assimilation. PMID- 4148398 TI - [Treatment of chronic coronary insufficiency]. PMID- 4148399 TI - [Activity of some peptidases in human blood leukocytes during phagocytosis]. PMID- 4148400 TI - [Beta-blocking agents once more]. PMID- 4148401 TI - Histochemical changes in developing mouse liver after administration of phenobarbital. PMID- 4148402 TI - Evolving concepts of the genetics of thyroid disease-a review. PMID- 4148403 TI - Case history number 75: hepatic damage after fluroxene anesthesia. PMID- 4148404 TI - [The liver in periarteritis nodosa]. PMID- 4148405 TI - Comparison of centrally mediated hypotensive action of methyldopa and DOPA in cats. PMID- 4148406 TI - The effects of isoproterenol, isoetharine and butyletharine on beta receptors. PMID- 4148407 TI - Influence of propranolol on the vascular effects of cadmium and isoproterenol in rabbit aorta. PMID- 4148408 TI - [Inotropic effects of several adrenergic beta blockers in a dog subjected to electrosystolic cardiac impulse]. PMID- 4148409 TI - Factors determining activity and selectivity of antifibrillatory agents on different types of fibrillation. PMID- 4148410 TI - Some cardiovascular effects of timolol a new beta-adrenergic blocking agent. PMID- 4148412 TI - Proceedings: Testicular tumors. Epidemiologic, etiologic, and pathologic features. PMID- 4148411 TI - Bone marrow transplantation-clinical results and problems. PMID- 4148413 TI - 20Alpha-hydroxysteroid dehydrogenase of cultured mammalian (HeLa S3) cells. PMID- 4148414 TI - Effect of some beta adrenoceptor blocking agents on skeletal neuromuscular transmission and motor co-ordination. PMID- 4148415 TI - Effect of beta-adrenoceptor antagonists on acetylcholine concentration of mouse brain. PMID- 4148416 TI - Susceptibility of recently isolated pathogenic bacteria to trimethoprim and sulfamethoxazole separately and combined. PMID- 4148417 TI - Trimethoprim-sulfamethoxazole in the treatment and prevention of purulent exacerbations of chronic bronchitis. PMID- 4148418 TI - Trimethoprim-sulfamethoxazole compared with ampicillin in acute infectious exacerbations of chronic bronchitis: a double-blind, crossover study. PMID- 4148419 TI - Synthesis of pivaloyloxymethyl 6-N'-cyanoamidinopenicillanates and the antibacterial activity of the corresponding acids. PMID- 4148420 TI - Monofluoromethanesulfonanilides. A new series of bronchodilators. PMID- 4148421 TI - Aromatic amino acid hydroxylase inhibitors. 3. In vitro inhibition by azadopamine analogs. PMID- 4148422 TI - Adrenergic agents. 1. Synthesis and potential beta-adrenergic agonist activity of some catecholamine analogs bearing a substituted amino functionality in the meta position. PMID- 4148423 TI - Steroid-induced nuclear binding of glucocorticoid receptors in intact hepatoma cells. PMID- 4148424 TI - Monoamine neurotransmitters and the pathophysiology of stroke and central nervous system trauma. PMID- 4148425 TI - Spectrophotometric determination of microgram quantities of acetylsalicylic anhydride in acetylsalicylic acid. PMID- 4148426 TI - Quantitative determination of imipramine and desipramine in human blood plasma by direct densitometry of thin-layer chromatograms. PMID- 4148427 TI - Imipramine and its metabolites in human brain. PMID- 4148428 TI - The inhibition of histamine formation in vivo. PMID- 4148429 TI - Lesions in the septal nuclei of the rat raise mean systemic arterial pressure and prevent the development of sound-withdrawal hypertension. PMID- 4148430 TI - The evaluation of the alpha-adrenoceptor blocking action of indoramin, phentolamine and thymoxamine on the rat and guinea-pig isolated mesenteric vasculature and aortic spiral preparations. PMID- 4148431 TI - The alpha-adrenoceptor blocking effect of indoramin on human isolated smooth muscle. PMID- 4148433 TI - The formulation and sterilization of a surgical lubricant gel based on carboxypolymethylene. PMID- 4148432 TI - Influence of electrolytes on the hydration of methylcellulose in solution. PMID- 4148434 TI - Letter: Effects of 5,6-dihydroxytryptamine on the metabolism of 5 hydroxytryptamine in the central nervous system of the rat. PMID- 4148435 TI - Catalepsy and stereotyped behaviour in rats treated chronically with methadone: relation to brain homovanillic acid content. PMID- 4148437 TI - Letter: Arachidonic acid lowers and indomethacin increases the blood pressure of the rabbit. PMID- 4148436 TI - Letter: Comparison of the blocking effects of antagonists of adrenaline and 5 hydroxytryptamine on their mutual receptors. PMID- 4148438 TI - Letter: Lack of influence of indomethacin on neurogenic vasodilatation in the hind-limb and spleen of the dog. PMID- 4148439 TI - Letter: Some factors modifying the metabolism of AH 8165 by rat liver homogenate in vitro. PMID- 4148440 TI - Letter: Effect of 3,4-dimethoxyphenethylamine on monoamine-depleted rats. PMID- 4148441 TI - Letter: Salbutamol: agonistic and antagonistic activity at beta--adrenoceptor sites. PMID- 4148442 TI - Letter: Cannabidiol and Cannabis sativa extract protect mice and rats against convulsive agents. PMID- 4148443 TI - Letter: Effects of antiparkinsonian drugs on neuroleptic-induced extrapyramidal signs in monkeys. PMID- 4148444 TI - Letter: Lipolysis induced by coffee and tobacco: its modification by insulin. PMID- 4148445 TI - Letter: Effect of various steroids and ACTH on methyprylon plasma levels and sleeping time in rats. PMID- 4148446 TI - Letter: Dithiocarbamate central effects in relation to their possible influence on drug metabolizing enzymes. PMID- 4148447 TI - Letter: A note on the analysis of disodium cromoglycate (Intal) in human urine. PMID- 4148448 TI - Letter: The transport number of noradrenaline as a function of pH. PMID- 4148449 TI - Letter: The crystallization of sulphadiazine by the solvent change method in turbulent conditions. PMID- 4148450 TI - Alkylation reactions of hydantoins and succinimides. PMID- 4148451 TI - Metabolism and anticonvulsant activity of deuterated N-demethyldiazepam. PMID- 4148452 TI - Polyarteritis nodosa in infancy: a diagnostic enigma. PMID- 4148453 TI - Pneumonia in New Guinea. I. Bacteriological findings in 632 adults with particular reference to haemophilus influenzae. PMID- 4148454 TI - Pneumonia in new guinea. II. Pneumococcal serotypes and the possible utility of polyvalent vaccines of capsular polysaccharides. PMID- 4148455 TI - Environmental dermatitis: patch tests in 1,000 cases of allergic contact dermatitis. PMID- 4148456 TI - Reactivity of lymphoid cells from mice humorally tolerant to histocompatibility antigens. PMID- 4148457 TI - [Role of so-called secondary disease in the pathogenesis of remissions in acute leukemia]. PMID- 4148458 TI - Effects of a beta-adrenergic agent (metaproterenol) on uteroplacental circulation. An angiographic study in the pregnant rhesus monkey. PMID- 4148459 TI - The placenta: immunologic or hemodynamic protector of the fetus? PMID- 4148460 TI - Editorial: New vasodilator drugs for hypertension. PMID- 4148461 TI - Myopathy associated with anticonvulsant osteomalacia. PMID- 4148463 TI - Letter: Suicidal attempts with beta-adrenoceptor blocking agents. PMID- 4148462 TI - Diseases of the skin. Management of eczema. II. PMID- 4148464 TI - Diseases of the skin. The management of pruritus. PMID- 4148466 TI - [15th Congress of the International Council of Nurses in Mexico City; from May 13 18, 1973]. PMID- 4148465 TI - [A new model: certified physicians' assistant (nursing)]. PMID- 4148467 TI - [15th Congress of the International Council for Nurses in Mexico City; from May 13-18, 1973. 1st Continuation]. PMID- 4148468 TI - [The effect of storage time and temperature on culturing micro-organisms from Liquoid-blood mixtures (author's transl)]. PMID- 4148469 TI - Proceedings: A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphasalazine (salazopyrin). PMID- 4148470 TI - Faith healing. A study of personality and function. PMID- 4148471 TI - The use of LSD in time-limited psychotherapy. PMID- 4148472 TI - Psychological studies of longer range L-DOPA therapy in Parkinsonism. PMID- 4148473 TI - C-reactive protein-like precipitins in plaice. PMID- 4148474 TI - Inhibition of local graft-versus-host reaction by anti-alloantibodies. PMID- 4148475 TI - Localisation of glutamine synthetase in chloroplasts. PMID- 4148476 TI - Effects of membrane stabilizers on glucuronidation and amino acid transport in cultures of rat hepatoma cells. PMID- 4148477 TI - Partial tolerance and immunity after adoptive abrogation of transplantation tolerance in the rat. PMID- 4148478 TI - [Automated measurement of gamma glutamyltranspeptidase]. PMID- 4148479 TI - A familial incidence of structurally restricted antibodies to pneumococcal polysaccharides. PMID- 4148480 TI - Rapid multichannel microfluorometry for metabolic and spectral studies in single living cells. PMID- 4148481 TI - Acquisition of an embryonal biochemical feature in the rat liver after portacaval shunt. PMID- 4148482 TI - Beta-sympatholytics as non-specific inhibitors of serum cholin-esterase. PMID- 4148483 TI - Visualization of immunoadsorption by immunofluorescence. PMID- 4148484 TI - [Incidence of dental caries in primary schools]. PMID- 4148485 TI - Hepatic and metabolic effects of alcohol (1966 to 1973). PMID- 4148487 TI - Aequorin luminescence during contraction of amphibian skeletal muscle. PMID- 4148486 TI - An evidence for the presence of beta-receptors in the seminal vesicle of guinea pig. PMID- 4148488 TI - Physician's assistants for Minnesota family practitioners. PMID- 4148489 TI - [Sensitivity of various bacterial strains to Oxacillin, Polfa]. PMID- 4148490 TI - Migraine treated with an antihistamine-analgesic combination. PMID- 4148491 TI - Oral and dental state in Helsinki preschool children. IV. Caries incidence in the deciduous dentition. PMID- 4148492 TI - [Post-traumatic decalcifying algodystrophy of the foot]. PMID- 4148493 TI - Comparative in vitro study concerning the effects of thrombin and serotonin on the platelet energy transferring system. PMID- 4148494 TI - [Adaptation of submarine crew members to high concentrations of carbon dioxide]. PMID- 4148495 TI - [A comparison between the MMPI, 16-PF and FPI in a small random sample]. PMID- 4148496 TI - Value of percutaneous transhepatic cholangiography in "institutional jaundice". PMID- 4148497 TI - The role of cyclic 3',5'-adenosine monophosphate in neuromuscular transmission. PMID- 4148499 TI - Failure to thrive, vomiting, and undescended testes in a two-month-old boy. PMID- 4148498 TI - [An antihistaminic with antidepressant action (author's transl)]. PMID- 4148500 TI - Mesenteric angiographic studies in children with regional enteritis. PMID- 4148501 TI - [Letter: Unilateral maldescensus testis]. PMID- 4148502 TI - Antibronchoconstrictor activity of two new phosphodiesterase inhibitors, a triazolopyrazine (ICI 58 301) and a triazolopyrimidine (ICI 63 197). PMID- 4148503 TI - Factors affecting the antidiuretic actions of the 18-monoacetate of (+) aldosterone and of a substance secreted by eart muscle, in rats. PMID- 4148504 TI - Further observations on the experimental antidysrhythmic activity of indoramin hydrochloride. PMID- 4148505 TI - A note on the effect of amantadine on body temperature in mice. PMID- 4148506 TI - Metabolism of amphetamines. Identification of N-oxygenated products by gas chromatography and mass spectrometry. PMID- 4148507 TI - The determination of fluorochlorocarbons in air and body fluids. PMID- 4148508 TI - A quantitative approach to the in vitro availability of drugs from some non-ionic surfactant solutions. PMID- 4148509 TI - The packing properties of moist bulk solids. PMID- 4148510 TI - Some properties of an oil-soluble phosphated fatty alcohol ethoxylate. PMID- 4148511 TI - The interaction of Escherichia coli and magnesium trisilicate in aqueous suspension. PMID- 4148512 TI - Letter: The effect of local anaesthetics on the incorporation of 32P into the phosphoinositides of rabbit vagus nerve. PMID- 4148513 TI - Letter: Prostaglandins as regulators of bradykinin responses. PMID- 4148514 TI - Letter: Preliminary investigation of the metabolism of piribedil (ET 495); a new central dopaminergic agonist and potential anti-parkinson agent. PMID- 4148515 TI - Letter: The activation of pineal hydroxyindole-O-methyltransferase by psychotomimetic drugs. PMID- 4148516 TI - Letter: The action of anti-inflammatory drugs in two models of inflammation. PMID- 4148517 TI - Letter: Amphetamine-induced inhibition of tyrosine hydroxylation in homogenates of rat corpus striatum. PMID- 4148518 TI - Letter: The influence of halothane on calcium uptake by isolated cell membranes. PMID- 4148519 TI - Letter: Pharmacokinetics of (+)-, (-)- and (plus or minus)-hexobarbitone in man after oral administration. PMID- 4148520 TI - Letter: Reduction of audiogenic seizure by delta8- and delta9- tetrahydrocannabinols. PMID- 4148521 TI - Letter: The fluorescence of paracetamol--a re-examination. PMID- 4148522 TI - Letter: The influence of tablet weight on compaction pressure-tablet density relations. PMID- 4148523 TI - [Gamma-glutamyl transpeptidase as a screening test (author's transl)]. PMID- 4148525 TI - [Organizational meeting]. PMID- 4148524 TI - Production by stimulated macrophages of factors depressing lymphocyte transformation. PMID- 4148526 TI - Proceedings: A new steroid anaesthetic-althesin. PMID- 4148527 TI - Proceedings: Medical aspects of ulcerative colitis in childhood. PMID- 4148528 TI - Chemotherapy in chronic organic brain syndrome--a review of the literature. PMID- 4148529 TI - Infarction of an abdominal undescended testis presenting as a calcified abdominal mass in a newborn. PMID- 4148530 TI - Posterior para-urethral diverticulum. Case report. PMID- 4148531 TI - Reconstruction of the plantar pad after degloving injuries of the foot. PMID- 4148532 TI - [Antilymphocyte serum as an immunosuppressant]. PMID- 4148533 TI - Where we stand. AB - To serve the interests of members and to function in the public interest, the California Medical Association must set policies and take positions on current issues affecting the health care of Californians. These policies then guide the activities of the Association in fulfilling its leadership role and its responsibility to the public.Delegates, elected by the membership of CMA's component medical societies, meet annually to deliberate and determine the policies and courses of action for the Association. Between meetings of these Delegates, the CMA Councilors, elected by their district membership, implement the directives of the Delegates and set interim policies. By this democratic process, the membership governs the CMA. Association members must be informed if they are to participate effectively in the affairs of their medical organizations. To disseminate better understanding of CMA's activities, position papers on current issues have been developed. They are based on House of Delegates resolutions and Council actions. Entitled "Where We Stand on Medical and Health Issues," these papers represent the current policy positions of CMA. Each paper is annotated to give the reference source of the policy actions. As with any organization, CMA policies are subject to timely revision. When policies are amended or new policies are adopted, new papers will be developed. PMID- 4148534 TI - Mackay-Marg tonometry by technicians. PMID- 4148536 TI - Echocardiographic assessment of idiopathic hypertrophic subaortic stenosis. PMID- 4148535 TI - The physician's associate-a task analysis. PMID- 4148537 TI - Studies on sweating in clinical and experimental thyrotoxicosis. PMID- 4148538 TI - An oxidative analytical procedure for some compounds containing the diphenylmethylidene group. PMID- 4148539 TI - Induction of adrenal catecholamine synthesising enzymes following mother-infant separation. PMID- 4148540 TI - Athletic injuries. PMID- 4148541 TI - Tooth decay. PMID- 4148542 TI - Effect of blockade of the alpha-adrenergic receptors on insulin response to glucose infusion in prediabetic subjects. PMID- 4148543 TI - In vitro biosynthesis of androgens in canine testes. PMID- 4148544 TI - [New aspects of the clinical importance of gamma-glutamyl-transpeptidase estimation in serum (author's transl)]. PMID- 4148545 TI - Beta-adrenergic effects on rat myometrium: mechanisms of membrane hyperpolarization. PMID- 4148546 TI - Adenyl and guanyl cyclase in rabbit gastric mucosa. PMID- 4148547 TI - Complement metabolism in rheumatoid arthritis. I. Longitudinal studies. PMID- 4148548 TI - The effect of certain drugs on the plasma protein binding of phenytoin. PMID- 4148549 TI - Dynamic synaptic communication: finding the vocabulary. PMID- 4148550 TI - Functional properties of the purified cholinergic receptor protein from Electrophorus electricus. PMID- 4148551 TI - Aminergic transmission. Introduction and short review. PMID- 4148552 TI - Effect of sodium, hemicholinium-3 and antiparkinson drugs on (14C)acetylcholine synthesis and (3H)choline uptake in rat striatal synaptosomes. PMID- 4148553 TI - Reduction in GADI activity from the dorsal lateral region of the deafferented rat spinal cord. PMID- 4148554 TI - Immunological studies of runting syndrome in rats inoculated with Friend virus. PMID- 4148555 TI - Serum luteinizing hormone and follicle stimulating hormone in normal children and patients with various clinical disorders. PMID- 4148556 TI - Electrophoretic investigation of some red cell enzymes in Iran. PMID- 4148557 TI - The secretion and development of nematocysts in a siphonophore. PMID- 4148558 TI - MAG spokesman defends Georgia physicians. PMID- 4148559 TI - Developmental inhibition of mosquitoes and the house fly by urea analogues. PMID- 4148560 TI - Laboratory transmission of Wisconsin isolates of a Cache Valley-like virus by mosquitoes. PMID- 4148561 TI - Adaptation of two mosquito cell lines to medium free of calf serum. PMID- 4148562 TI - [Beta-adrenergic blockade and function of the respiratory system (author's transl)]. PMID- 4148564 TI - Anaerobic infection of the paranasal sinuses. PMID- 4148563 TI - [The treatment of essential hypertension (author's transl)]. PMID- 4148565 TI - [Sugar and caries in the light of history]. PMID- 4148566 TI - [Some physiopathological mechanisms of allergizing activity of infectious agents]. PMID- 4148567 TI - [Most frequently encountered allergens in Poland. Round-Table Conference organized by the Allergology Section of the Polish Medical Society in Warsaw on May 6th, 1972]. PMID- 4148569 TI - The water metabolism of a small East African antelope: the dik-dik. PMID- 4148568 TI - Oral and dental state in Helsinki preschool children. II. Caries in early erupting permanent teeth. PMID- 4148570 TI - The fine structure of the PD proprioceptor of Cancer pagurus. I. The receptor stand and the movement sensitive cells. PMID- 4148571 TI - The fine structure of the PD proprioceptor of Cancer pagurus. II. The position sensitive cells. PMID- 4148572 TI - Molecular alterations in the plasma membrane of sporangiospores of Phycomyces related to germination. PMID- 4148573 TI - The effect of atropine on acetylcholine action at the neuromuscular junction. PMID- 4148574 TI - Some comments about the personality comparison of incarcerated and street heroin addicts. PMID- 4148575 TI - Indications of psychopathology in applicants to a county methadone maintenance program. PMID- 4148576 TI - Demographic and MMPI characteristics of male and female state hospital alcoholic patients. PMID- 4148577 TI - Seasonal variation of personality of college students as measured by the MMPI. PMID- 4148578 TI - Evaluating a dental caries preventive programme. PMID- 4148579 TI - Morphine lethality in rats: effects of inhibitors of brain catecholamine synthesis and methylation. PMID- 4148580 TI - Attempts at treatment of intracranial arterial spasm in animals and human beings. PMID- 4148581 TI - Dexetimide: an effective drug for the control of extrapyramidal symptoms induced by pipothiazine palmitate. PMID- 4148582 TI - Massive lethal hepatic necrosis in rats anesthetized with fluroxene, after microsomal enzyme induction. PMID- 4148583 TI - Metabolism of vasoactive hormones by lung. PMID- 4148584 TI - [Isolation of a West-Nile virus in the extreme south of the Algerian Sahara (Djanet)]. PMID- 4148585 TI - The substrate analog bromopyruvate as a substrate, an inhibitor and an alkylating agent of malic enzyme of pigeon liver. PMID- 4148586 TI - 3-Hydroxybenzoate 4-hydroxylase from Pseudomonas testosteroni. PMID- 4148587 TI - Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution. PMID- 4148588 TI - The doctor and the pharmaceutical industry. PMID- 4148589 TI - Adjustment of welfare recipients and applicants: investigation of some relevant factors. PMID- 4148590 TI - [Ansamycins, a novel class of microbial metabolites]. PMID- 4148591 TI - Pyogenic meningitis in infants and children. A clinical and bacteriologic study. PMID- 4148592 TI - Biohydrogenation accompanying the beta-oxidation of unsaturated fatty acids by Candida. PMID- 4148593 TI - Changes in enzyme activities of rat liver peroxisomes under various physiological conditions. PMID- 4148594 TI - The properties of trehalase from the mosquito-parasitizing water mold, Lagenidum sp. PMID- 4148595 TI - An approach to laboratory evaluation. PMID- 4148596 TI - Involvement: form the classroom to the community. PMID- 4148598 TI - The development and use of level objectives in a diploma program. PMID- 4148597 TI - Conceptual models as guides to clinical nursing specialization. PMID- 4148599 TI - Orientation to the psychiatric nursing experience. PMID- 4148600 TI - Students' experiences with the prenatal care of high-risk pregnant women. PMID- 4148601 TI - The surgeon's assistant's education and role. PMID- 4148602 TI - The formation of "K-region" epoxides as hepatic microsomal metabolites of 7 methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and their 7 hydroxymethyl derivatives. PMID- 4148603 TI - The effect of dietary protein and fat on the activity of aryl hydrocarbon hydroxylase in rat liver, kidney and lung. PMID- 4148604 TI - Effects of acute and chronic administration of desmethylimipramine on the content of norepinephrine and other monoamines in the rat brain. PMID- 4148605 TI - [Influence of substituants on microsomal dealkylation of aromatic N-, O-, and S alkyl compounds]. PMID- 4148606 TI - Health sciences curricula: public health microbiology and medical laboratory technology. PMID- 4148607 TI - The message of combined epidemiological and laboratory investigations into the caries condition of Polynesians. PMID- 4148608 TI - [The University of Quebec at Trois-Rivieres. Are they or are they not busy preparing physicians' assistants?]. PMID- 4148609 TI - Personality characteristics of male native American alcoholic patients. PMID- 4148610 TI - Physiology of the eye pertinent to anesthesia. PMID- 4148611 TI - Slaframine (slobber factor) toxicosis. PMID- 4148613 TI - [15th Quadrennial Congress of the International Council for Nurses]. PMID- 4148612 TI - Regulation of tyrosine hydroxylase activity in mouse neuroblastoma clone N1E-115. PMID- 4148614 TI - Letter: Adrenergic-blocking drugs in hyperthyroidism. PMID- 4148615 TI - Further studies on the mitochondrial changes during the life cycle of Plasmodium berghei: electrophoretic studies on isocitrate dehydrogenases. PMID- 4148616 TI - Citric acid cycle activity and chloroquine resistance in rodent malaria parasites: the role of the reticulocyte. PMID- 4148617 TI - Nocturnal penile tumescence and sleep of convicted rapists and other prisoners. PMID- 4148618 TI - The oxidoreduction state of free NAD(P) and mass-action ratio of total nicotinamide nucleotides in isolated rat-liver mitochondria. PMID- 4148619 TI - Light-induced oxidation-reduction reactions in a cell-free preparation from the blue-green alga Nostoc muscorum: the role of cytochrome f, cytochrome b558, C550, and P700 in noncyclic electron transport. PMID- 4148620 TI - Crisis theory: a definitional study. PMID- 4148621 TI - Beta-adrenergic blockade and plasma renin activity in borderline hypertension. PMID- 4148622 TI - Hepatic function tests. PMID- 4148623 TI - Immunoglobulins of the middle ear fluid in acute otitis media: relationship to serum immunoglobulin concentrations and bacterial cultures. AB - Immunoglobulin concentrations were studied in 255 specimens of middle ear fluid (MEF) from 165 episodes of acute otitis media in children. There were significant amounts of all three major immunoglobulins (Ig) in MEF, the mean concentration of IgA being 39 mg/100 ml, of IgM 63 mg/100 ml, and of IgG 383 mg/100 ml. Secretory component was present in all 10 MEF specimens in which it was sought. In patients over 9 months of age, there was a decreased likelihood of isolating pathogenic bacteria from MEF if the patient had higher concentrations of IgA in MEF than in simultaneously obtained serum. IgA concentrations were greater in MEF than in serum in almost half the patients, and the mean MEF-serum ratio for IgA was 1.38. Thus, it would appear that in this disorder MEF represents primarily a secretory response to inflammation rather than a transudate. PMID- 4148624 TI - In vitro activity of diethylcarbamazine on the infective larvae, microfilariae and adult worms of Breinlia sergenti. PMID- 4148625 TI - Effect of histamine and its methyl derivatives on cyclic AMP metabolism in gastric mucosa and its blockade by an H2 receptor antagonist. AB - In a cell-free system prepared from guinea pig gastric mucosa, histamine and Nalpha-methyl-histamine produced dose-dependent stimulation of cyclic AMP formation and 1,4-methylhistamine had a minimal stimulatory effect. N-methyl-N' (2-[5-methylimidazole-4-yl-methylthio]-ethyl) -thiourea (metiamide), a new H2 receptor inhibitor, selectively blocked the stimulation of adenylate cyclase by histamine and its active methyl derivative but had no substantial effect on the basal adenylate cyclase activity or adenylate cyclase stimulated by sodium fluoride. Metiamide inhibited the histamine stimulation of adenylate cyclase at 1/100 the concentration of the histamine. Histamine, its methyl derivatives, and metiamide did not influence the activity of cyclic AMP phosphodiesterase from gastric mucosa. Therefore, histamine stimulates gastric mucosal adenylate cyclase via interaction with the H2 receptor without influencing cyclic AMP breakdown, and N-methylation of histamine on the side chain preserves or even increases its stimulating ability. On the other hand, N-methylation in the ring nearly abolishes the ability of histamine to interact with the H2 receptor. PMID- 4148626 TI - National health policy: objectives and strategy. PMID- 4148627 TI - Cytochemical examination of the effect of histamine on adenylate cyclase activity in guinea pig heart tissue. PMID- 4148629 TI - Soldering porcelain-fused-to-metal fixed partial dentures. PMID- 4148628 TI - GLC analysis of metapyrilene in plasma and urine using a sulfur-specific flame photometric detector. PMID- 4148630 TI - [Effect of drugs on fall-out nystagmus and Bekhterev nystagmus]. PMID- 4148631 TI - [Radiation oxidation of water mixtures from water-containing human wastes]. PMID- 4148632 TI - Hereditary angioneurotic oedema. PMID- 4148633 TI - Experimental osteogenesis with decalcified allogeneic bone matrix in palatal defects. PMID- 4148634 TI - Central nervous system and autonomic nervous system effects of amantadine and of some standard anti-Parkinson drugs. PMID- 4148635 TI - [Problems of immunology and pregnancy]. PMID- 4148636 TI - Effect of clonazepam (Ro 5-4023) on epileptic seizures. PMID- 4148637 TI - Clonazepam (Ro 5-4023) in the treatment of myoclonus epilepsy. Four case reports. PMID- 4148638 TI - Etiologies and characteristic features of pneumonias in a municipal hospital. PMID- 4148639 TI - [The effect of a spleen dialysate on the genital organs of the male rat. 1. Morphologic and enzyme histochemical studies]. PMID- 4148640 TI - Incorporation of radioactive acetate into diacetyl by Streptococcus diacetilactis. AB - Streptococcus diacetilactis was grown in a partially defined, lipoic acid-free medium containing radioactive acetate with and without addition of 0.1% unlabeled sodium pyruvate. Labeled carbon was incorporated into diacetyl, but neither the amount of diacetyl produced nor its specific activity was influenced by addition of pyruvate. Acetoin had low specific activity, indicating that it was a mixture of radioactive and nonradioactive acetoin. The specific activity of acetoin was lower when pyruvate, a precursor of unlabeled acetoin, was added to the medium, which indicated that the radioactive acetoin was produced from radioactive diacetyl by diacetyl reductase. Results substantiate condensation of acetyl coenzyme A with hydroxyethylthiamine pyrophosphate as the in vivo mechanism for synthesis of diacetyl. PMID- 4148641 TI - Mechanism and biosynthetic requirements for F plasmid replication in Escherichia coli. PMID- 4148642 TI - A lipotrope-dependent increase of histidase and urocanase in the livers of choline-deficient rats and in the Reuber H-35 transplanted hepatoma. PMID- 4148643 TI - The effect of some biphenyl solubilizing and suspending agents on biphenyl 4 hydroxylase of rabbit liver microsomes. PMID- 4148644 TI - [Stannous fluoride in dental caries prevention in adults]. PMID- 4148645 TI - [Arteritis]. PMID- 4148646 TI - [Clinicopathological conference. XI. Rapidly progressive uremia, fever and upper abdominal pain]. PMID- 4148647 TI - Graft-vs.-host reaction in tissue culture. AB - The primary purpose of this study has been to validate the in vitro graft-vs. host reaction as an experimental system. Time-dose studies have been presented for cells obtained from spleen, thymus, cortisone-treated thymus, inguinal lymph node, mesenteric lymph node, thoracic duct, and bone marrow cells. Both the degree of splenomegaly and the onset of spleen enlargement were found to be dependent on the number and source of cells tested. The effect of several immunosuppressive agents was examined. Amantadine was found to suppress completely the graft-vs.-host reaction in vitro when present at a concentration of 75 microg/ml. Pretreatment of effector cells with mitomycin C prevented their subsequent ability to cause a graft-vs.-host reaction. The effect of X irradiation on immunocompetence of spleen cells in vitro paralleled the known effect of irradiation on in vivo immunocompetence. Preimmunization did not increase the number or effectiveness of immunocompetent cells when measured under standard in vitro conditions. Preimmunization did, however, permit persistence of immunocompetence after immunosuppressive doses of X irradiation. Studies using congenic lines, moreover, indicated that the preimmunization effect could be demonstrated in strain combinations differing only in factors determined by the H 2 complex of genes. A weak graft-vs.-host reaction could be detected in strain combinations not involving differences at the H-2 locus. The potential of the in vitro graft-vs.-host reaction as a highly reproducible, quantifiable, internally controlled, and experimentally accessible system for study of such critical problems as cell differentiation and cell interactions is discussed. PMID- 4148649 TI - [Urinary excretion of trifluoroethanol following fluroxene anesthesia in man]. PMID- 4148648 TI - Hormone-like activity of a thymus humoral factor on the induction of immune competence in lymphoid cells. AB - Experiments reported here were performed to understand the mechanism by which THF increases the immunocompetence of spleen cells from NTx mice. Dibutyryl cAMP or substances which increase intracellular levels of cAMP in lymphocytes such as Poly(A:U), theophylline, or PGE(2) were shown to mimic the effect of THF and confer reactivity in an in vitro GvH response to spleen cells from NTx mice. Flufenamic acid, an antagonist to PGE(2), was shown to inhibit the induction of competence by this substance. It was found that THF induces competence by activating membranal adenyl cyclase which leads to a rise in intracellular cAMP in thymus-derived cells only. These biochemical changes occur before antigenic stimulation and are unrelated to antigenic challenge. These findings indicate that THF exerts its effect via cAMP and are in agreement with the concepts which permit to classify THF as a thymus hormone. PMID- 4148650 TI - Evidence for an inhibitory product-cytochrome P-450 complex generated during benzphetamine metabolism by liver microsomes. PMID- 4148651 TI - Transaminases in rat retina during development. PMID- 4148652 TI - Accumulation of adenosine cyclic 3',5'-monophosphate in rat cerebral cortical slices. Stimulatory effect of alpha and beta adrenergic agents after treatment with 6-hydroxydopamine, 2,3,5-trihydroxyphenethylamine, and dihydroxytryptamines. PMID- 4148653 TI - Effects of tranquilizers on the glutamate dehydrogenase-glutamate-oxalacetate transaminase complex. PMID- 4148654 TI - Reserpine-like effects of harmine on isolated adrenal medullary vesicles. PMID- 4148655 TI - Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine. PMID- 4148656 TI - Evidence against participation of cytochrome b5 in the hepatic microsomal mixed function oxidase reaction. PMID- 4148657 TI - The mechanism of infection in patients with diabetes mellitus: a review of leukocyte malfunction. PMID- 4148658 TI - Editorial: Hypertonic glucose and improved critical organ performance. PMID- 4148659 TI - Drug and alcohol abuse among psychiatric admissions. A multidrug clinical tosicologic study. PMID- 4148660 TI - Specific indications for different classes of phenothiazines. PMID- 4148662 TI - Membrane differentiation in phototrophically growing Rhodospirillum rubrum during transition from low to high light intensity. PMID- 4148661 TI - Altered heat-lability of a fraction of glutathione reductase in aging human lens. AB - An unusually heat-labile fraction of glutathione reductase appears in human lens at about an age of 32 years. No such change was found in glucose 6-phosphate dehydrogenase nor in 3-phosphoglycerate kinase. The change is an intrinsic property of glutathione reductase. A greater proportion of the altered glutathione reductase was found in the core, the older part, of the lens. No evidence of a second band of activity was obtained after electrophoresis. Possible interpretations of the results, including errors of protein synthesis, production of a new isoenzyme and post-synthetic changes, are discussed. PMID- 4148664 TI - [Letter: Sulfobromophtalein or gamma-glutamyl-transpeptidase?]. PMID- 4148663 TI - N-oxidation of a tertiary amine (N,N-dimethylaniline) by human fetal liver microsomes. PMID- 4148665 TI - [Letter: Cryptorchism in adults]. PMID- 4148666 TI - Integration efficiency in DNA-induced transformation of Pneumococcus. I. A method of transformation in solid medium and its use for isolation of transformation deficient and recombination-modified mutants. AB - A method of transformation on solid medium especially adapted for pneumococcus has been developed. Under specific conditions, all colonies that are allowed to grow in the presence of transforming DNA for six hours give rise to transformed bacteria. Combined with replica plating this technique has been used to isolate mutants modified with regard to recombination. Most of the mutants found are transformation-defective and show a large diversity in their response to ultraviolet light. Some of these mutants have lost their ability to take up transforming DNA. One shows a reduced yield of transformants for a given quantity of DNA taken up. Mutants that manifest altered behavior with regard to marker efficiencies have also been isolated. One of these exhibits a decrease in the transformation efficiency of only the high efficiency markers and two mutants show a decrease in the transformation efficiency of the low efficiency markers. PMID- 4148667 TI - Integration efficiency in DNA-induced transformation of Pneumococcus. II. Genetic studies of mutant integrating all the markers with a high efficiency. AB - Transformation of the pneumococcus mutant 401 by DNA's bearing the standard reference marker and several other markers belonging to two unlinked loci has shown that differences in the integration efficiencies of these markers were considerably reduced in this strain compared to the wild-type strain Cl(3). The sensitivities of mutant 401 to ultraviolet light and to X-ray irradiation are the same as those of Cl(3). However, in 401 all the markers tested are more resistant to inactivation as shown by transformation of 401 and Cl(3) by ultraviolet irradiated DNA. The increase in resistance is greater for low efficiency (LE) markers than for high efficiency (HE) markers.-The decreased discrimination between LE and HE markers in strain 401 is not due to a mechanism related to modification of markers in the transforming DNA by the recipient cells, nor are the proteins inducing competence of the cells responsible for the differences in the integration efficiencies of various markers.-Genetic studies of the fate of recombinants as well as the measure of the amount of DNA taken up have shown that all the markers are integrated in strain 401 by the same recombination process, that specific to high efficiency markers. PMID- 4148668 TI - [Hemodynamic effect of Nifedipine (BAY a 1040) before and following cardiac sympathetic blockade by practolol (ICI 50 172)]. PMID- 4148669 TI - The regulation of fatty acid synthesis in human skin fibroblasts. Inhibition of fatty acid synthesis by free fatty acids. PMID- 4148670 TI - Studies on the tryptophan and drug-binding properties of human serum albumin fragments by affinity chromatography and circular dichroism measurements. PMID- 4148671 TI - Stimulation of taurodeoxycholate 7alpha-hydroxylase of rat liver by adenosine 3':5'-monophosphate and saturated fatty acids. PMID- 4148672 TI - Specificity in the association of glyceraldehyde 3-phosphate dehydrogenase with isolated human erythrocyte membranes. PMID- 4148673 TI - Sequential solubilization of microsomal mixed function oxidases. PMID- 4148674 TI - The mechanism of activation of glutamate dehydrogenase-catalyzed reactions by two different, cooperatively bound activators. PMID- 4148675 TI - Hepatic organelle interaction. 3. Mitochondrial modification of microsomal drug metabolism. PMID- 4148676 TI - Regulation of de novo fatty acid biosynthesis in the n-alkane-utilizing yeast, Candida 107. PMID- 4148677 TI - Abnormally low activities of fumarate hydratase and malate dehydrogenase in oxygen-sensitive cultures of Spirillum volutans. PMID- 4148678 TI - Depressive effect of 7,12-dimethylbenz(alpha)anthracene and ionizing irradiation on bone marrow colony-forming cells. PMID- 4148679 TI - Parameter sensitivity in insect population modeling. PMID- 4148680 TI - [Basic characteristics of equipment for oxygen regeneration in sealed chambers, based on electrolysis using solid electrolytes]. PMID- 4148681 TI - [Course of the infectious process and functional activity of lung macrophages in mice exposed to a hyperoxic atmosphere]. PMID- 4148682 TI - [Rectal effect of salazopyrine in ulcerative colitis during a double-blind study]. PMID- 4148684 TI - The surgeon's assistant must be more than just a title. PMID- 4148683 TI - Tetanus: principles of management and review of 37 cases. PMID- 4148685 TI - Effect of chronic exposure to carbon disulphide upon some components of the electron transport system in rat liver microsomes. PMID- 4148686 TI - Differential sensitivity of rat liver and rat hepatoma cells to alpha-amanitin. PMID- 4148687 TI - Influence of non-steroid anti-inflammatory and immunosuppressive drugs on hepatic tryptophan pyrrolase activity in rats. PMID- 4148688 TI - Effect of catecholamines on plasma growth hormone in dogs. PMID- 4148689 TI - A simple general method for the preparation of "6-immobilized" analogues of AMP, ATP, NAD and of other adenine-containing compounds for affinity chromatography. PMID- 4148690 TI - Warfarin resistance and DT diaphorase activity in the rat. PMID- 4148691 TI - Strain differences in liver DT diaphorase activities. PMID- 4148692 TI - The template binding and self-assembly in the reconstitution of microsomal redox chains: electron carriers which do and do not bind with microsomal membranes. PMID- 4148693 TI - Localization of glutaminase in rat liver. PMID- 4148694 TI - Guest editorial: The 15th Quadrennial Congress of the International Council of Nurses and continuing education. PMID- 4148695 TI - Electrophoretic characterization of classical Tetrahymena pyriformis strains. PMID- 4148696 TI - [Complications of regional anaesthesia and their treatment (author's transl)]. PMID- 4148698 TI - Inconstant association of aequorin luminescence with tension during calcium release in skinned muscle fibres. PMID- 4148697 TI - Further evidence against post-transcriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells. PMID- 4148699 TI - [Experimental arterial thrombosis. Effect of an alpha blocking agent: nicergoline]. PMID- 4148700 TI - [Pharmacological basis of the symptomatic treatment of arterial hypertension. I. Hemodynamic effects, mechanisms of action and side effects of antihypertensive agents]. PMID- 4148701 TI - Inhibition of the oxidation of glutamate and isocitrate in liver mitochondria at a specific NADP+-reducing site. AB - The cation-complexing carboxylic-acid antibiotic X-537A, at concentrations far below that required for ionophorous activity, selectively inhibits the oxidation of glutamate and isocitrate by liver mitochondria in steady-state 3. The site of inhibition has been localized specifically at the reduction of NADP(+). Glutamate and isocitrate dehydrogenases, the oxidation of NAD(+)-dependent substrates, pyridine nucleotide transhydrogenations, and the respiratory chain between NADH (or NADPH) and O(2) are unaffected by the antibiotic X-537A. Kinetic evidence, i.e., competition between chlorotetracycline (a fluorescence probe for membrane bound bivalent cation) and X-537A, indicates that the NADP(+)-reducing, antibiotic-sensitive site is most probably associated with the inner mitochondrial membrane. PMID- 4148702 TI - Marker discrimination in transformation and mutation of pneumococcus. AB - Earlier investigations of pneumococcal transformation revealed a function (hex(+)) responsible for severely reducing the transformation yield of certain markers. A mutational alteration (hex(-)) responsible for the loss of this function has been transferred into a hex(+) strain to permit a comparison of the hex(+) and hex(-) phenotypes in an isogenic background. The loss of the hex(+) function results both in a loss of the capacity to eliminate the low efficiency markers in transformation and a substantial increase in the spontaneous mutation rate. These properties of the hex(-) strain could result from the loss of a capacity to eliminate certain classes of mismatched base pairs that occur as intermediates in both transformation and mutagenesis. PMID- 4148703 TI - Guanylate cyclase: inhibition by light in retinal photoreceptors. AB - Guanylate cyclase activity of retinal rod outer segments was measured by an assay procedure that minimizes the technical problems caused by the high activity of cyclic nucleotide phosphodiesterase in neural tissue. Cyclase activity in rods is significantly higher than in brain. Moreover, activity is two-fold higher in dark adapted rods than in light-bleached rods, a sensitivity that is lost when the preparation is treated with detergent. PMID- 4148705 TI - The optimum age to correct cryptorchidism. PMID- 4148704 TI - Antireceptor antiserum causes specific inhibition of reactivity to rat histocompatibility antigens. AB - The antigen receptor of lymphocytes destined to form antibody appears to have the characteristics of the immunoglobulin produced. Antibody directed against the combining region of this immunoglobulin should interact with the combining region of the cell receptor for the antigen. Purified Lewis rat alloantibody prepared against Brown Norway (BN) rat histocompatibility antigens was used to immunize L x BN F(1) hybrids. The resultant antiserum has anti-receptor activity because (i) it yields precipitin lines in gel diffusion when reacted against the immunizing alloantibody; (ii) it inhibits the hemagglutinin antibody response of Lewis rats to BN histocompatibility antigens; and (iii) it inhibits the local graft-versus host response of Lewis lymphoid cells against BN antigens. This suggests that antireceptor antibody may inhibit cell-mediated responses as well as antibody responses to histocompatibility antigens and may play a role in the regulation of immune responses to such antigens. PMID- 4148706 TI - [Classification of sources of harmful admixtures]. PMID- 4148707 TI - [Neurological indices of fatigue in flight personnel in long-range and military transport aviation]. PMID- 4148708 TI - Preoperative localization of pheochromocytoma. PMID- 4148709 TI - Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro. PMID- 4148710 TI - Comparison of the antihistaminic effect of burimamide and mepyramine and their effect on the activity of histamine methyltransferase. PMID- 4148711 TI - [VII International Congress of Obstetrician-Gynecologist]. PMID- 4148712 TI - [Pharmacological action of 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2 pyrolinone hydrochloride (doxapram). 1. The action on the central nervous system]. PMID- 4148713 TI - Enzymatic studies on the metabolism of the tetrahydrofurfuryl mercaptan moiety of thiamine tetrahydrofurfuryl disulfide. II. Sulfide and sulfoxide oxygenases in microsomes. PMID- 4148714 TI - Enzymatic studies on the metabolism of the tetrahydrofurfuryl mercaptan moiety of thiamine tetrahydrofurfuryl disulfide. 3. Oxidative cleavage of the tetrahydrofuran moiety. PMID- 4148715 TI - Non-mitochondrial electron transfer system in anaerobically grown yeast cells. PMID- 4148716 TI - The effect of 0.2 percent sodium fluoride mouthrinse in the prevention of dental caries in school children born and reared in a non-fluoridated community. PMID- 4148717 TI - Selective blocking action of hexamethonium on the inhibitory postsynaptic responses of aplysia ganglion cells. PMID- 4148718 TI - [Experience of a public health physician's assistant in interactions with people (community health)]. PMID- 4148720 TI - [4th million persons registered]. PMID- 4148719 TI - [Epidemiological study on dental caries among the pupils of the elementary schools of Cyprus and the fluoride content of drinking water]. PMID- 4148721 TI - [Nurses' study instead of struggle]. PMID- 4148722 TI - [Phagocytic activity and characteristics of the metabolism of mouse alveolar and peritoneal macrophages]. PMID- 4148724 TI - [New anti-curare and analeptic drug, Pimadin, and its use in anesthesia]. PMID- 4148723 TI - Immunodeficiency and cancer. PMID- 4148725 TI - Role of peroxide in phagocytic killing of pneumococci. AB - Two mutants of a pneumococcus type I with diminished peroxide production were selected from a population of nitrosoguanidine-treated cells. White cells of normal patients killed the mutant pneumococci as well as the otherwise isogenic wild-type strain. In patients studied with chronic granulomatous disease, however, the peroxide-poor strain was killed far less well than the wild type. These studies indicate that the removal of a peroxide-generating system in the phagocytic vacuole specifically brings forth the killing defect in chronic granulomatous disease. PMID- 4148726 TI - Effect of trimetoquinol on skeletal muscle contraction in rabbits. Comparison with epinephrine and isoproterenol. PMID- 4148727 TI - [Can imipramine-chlorpyramine be teratogenic?]. PMID- 4148728 TI - [Cooperation of the Scandinavian countries]. PMID- 4148730 TI - [15th quadrennial congress of the International Council of Nurses]. PMID- 4148729 TI - [Practical medical treatment of essential arterial hypertension]. PMID- 4148731 TI - [15th Congress of the Internationsl Council of Nurses, May 1973 in Mexico City]. PMID- 4148732 TI - [Renovascular hypertension in children]. PMID- 4148733 TI - [Flavoprotein-iron-sulfur-protein complexes, with special reference to the catalytic activities of the ferredoxin NADP reductase-ferredoxin complex (author's transl)]. PMID- 4148734 TI - The threat of the physician's assistant; implications for nursing education. PMID- 4148735 TI - [Serum urocaninase in circulatory insufficiency]. PMID- 4148736 TI - [15th Congress of the International Council of Nurses, 1973 in Mexico City]. PMID- 4148737 TI - [Unilateral cryptorchism: a spermiologic, endocrinologic and cytogenetic study of 216 adult males (author's transl)]. PMID- 4148738 TI - [A new method for studying influences of oecology on spermatogenesis in the rat (author's transl)]. PMID- 4148739 TI - [Fertility and trauma (author's transl)]. PMID- 4148740 TI - The relation of adenyl cyclase to the activity of other ATP utilizing enzymes and phosphodiesterase in preparations of rat brain; mechanism of stimulation of cyclic AMP accumulation by adrenaline, ouabain and Mn++. AB - 1. The mechanism of stimulation of cyclic adenosine 3',5'-monophosphate (cyclic AMP) accumulation by adrenaline and ouabain and the effect of Mn(++) substitution for Mg(++) as the metal ion requirement of this system was studied in cell-free preparations of adenyl cyclase from rat brain.2. In the rat cerebral cortex preparation, substitution of Mn(++) for Mg(++) significantly increased cyclic AMP accumulation while significantly inhibiting adenosine triphosphate (ATP) and adenosine diphosphate (ADP) hydrolysis and adenosine 5'-monophosphate (AMP) accumulation. In the synaptic membrane preparation, in the absence of NaF, the highest amount of ATP hydrolysis was obtained in tissue prepared with Mn(++) and incubated with Mg(++); under these conditions cyclic AMP accumulation was equal to that produced under any other condition and significantly higher than that observed in the presence of Mg(++) prepared and Mg(++) incubated tissue.3. Preparation and/or incubation of tissue with Mn(++) significantly reduced phosphodiesterase (PDE) activity compared to that observed in Mg(++) prepared tissue.4. Adrenaline and ouabain both significantly increased cyclic AMP accumulation in the rat cerebral cortex preparation but did not inhibit ATP or ADP hydrolysis. In the synaptic membrane preparation, in the presence of 0.01 mM Ca(++), adrenaline but not ouabain significantly increased cyclic AMP accumulation. Phenoxybenzamine (0.1 mM) and pronethalol (0.1 mM) significantly inhibited adrenaline-induced cyclic AMP accumulation in both these preparations.5. Ouabain and adrenaline both failed to stimulate cyclic AMP accumulation in the presence of Mn(++) prepared and/or incubated tissue.6. Ouabain and adrenaline had no effect on PDE activity in either of these preparations.7. It was concluded that Mn(++) increased cyclic AMP accumulation in part by indirect inhibition of ATP and ADP hydrolysis which provides inhibitors of cyclic AMP destruction, by direct stimulation of adenyl cyclase and by inhibition of cyclic AMP destruction in a way unrelated to nucleotide inhibition of PDE. Adrenaline and ouabain appeared tp stimulate cyclic AMP accumulation in a more direct manner. PMID- 4148741 TI - Trans-synaptic regulation of adrenergic neuron development: inhibition by ganglionic blockade. PMID- 4148742 TI - Studies on the identity of the optic nerve transmitter. PMID- 4148743 TI - Brain (NA+ + K+)-activated adenosine triphosphatase activity and neurotransmitter uptake in alcohol-dependent rats. PMID- 4148744 TI - Central actions of shikimin and tutin. PMID- 4148745 TI - Ecological studies on the breeding of Aedes aegypti and other mosquitos in shells of the giant African snail Achatina fulica. AB - The breeding of larvae of Aedes aegypti, Aedes simpsoni, and Eretmapodites quinquevittatus in empty shells of Achatina fulica was studied in the coastal zone of Dar es Salaam, Tanzania. The average density of shells was estimated to be 228 per ha. From 11 to 35% were positive for mosquito larvae. A. aegypti were found in 82-84% of positive shells; A. simpsoni in 8-13%. On Msasani peninsula, during the 3-month rainy season April-June 1970, the larval density of A. aegypti in shells was estimated at 1 100 per ha, that of A. simpsoni and E. quinquevittatus being estimated at 60 and 280 larvae per ha, respectively.Empty shells of A. fulica may contain up to 250 ml of water (average: 56.5 ml). The number of larvae per shell varies from 1 to 35 (average: 8.4) and it was estimated that, depending on the availability of food, and other factors, approximately 10 ml of water are required per larva. Viable eggs of A. aegypti were still to be found in 4% of the shells at the end of the dry season. PMID- 4148746 TI - Demonstration of serum gamma-glutamyl transpeptidase isoenzymes using cellogel electrophoresis. PMID- 4148747 TI - The effects of physostigmine in phenothiazine resistant chronic schizophrenic patients: preliminary observations. PMID- 4148748 TI - Combined use of ECT and psychotropic drugs: antidepressives and antipsychotics. PMID- 4148749 TI - [Dentition of workers of the salt mines in Wieliczka]. PMID- 4148750 TI - [Dynamics of caries of the permanent teeth of children in Szczecin in the light of some indexes of caries]. PMID- 4148751 TI - Peroxisomes and hydrogenosomes in protozoa. PMID- 4148753 TI - Anatomy and innervation ratios in motor units of cat gastrocnemius. AB - 1. Muscle fibres belonging to single motor units of identified type were studied in frozen sections of cat medial and lateral gastrocnemius muscles. Reconstruction of the distribution of fibres in individual units showed that the territories of all three physiological types present in the cat medial gastrocnemius were quite extensive. Within its territory, fibres belonging to the studied unit were distributed more or less uniformly without localized collections. The density of unit fibres suggests that, in cat medial gastrocnemius, a given region of the muscle may be shared by as many as fifty different muscle units.2. Direct determination of innervation ratios in identified muscle units required complete reconstruction of the three-dimensional distribution of unit fibres within the whole medial gastrocnemius. Satisfactory results were obtained with two type FF units and one type FR unit.3. Indirect estimates of the average innervation ratios expected for muscle units of different physiological type were obtained using counts of muscle fibres with characteristic histochemical profiles and data on relative frequencies of motor units of known type in the medial gastrocnemius unit pool. Such indirect estimates of innervation ratios agreed with the results of direct fibre counts in identified units for types FF and FR muscle units. Taken in sum, the available evidence suggests that an average muscle unit in the cat medial gastrocnemius contains between 400 and 800 muscle fibres, irrespective of physiological type.4. Tension production by single muscle units depends on a number of factors, including innervation ratio, the cross-sectional areas of unit fibres and the specific tension outputs of the unit fibres. The present results suggest that the specific tension output of gastrocnemius type S unit muscle fibres is considerably smaller (about 0.6 kg/cm(2)) than in either FF units (about 1.5-2.0 kg/cm(2)) or type FR units (2.6-2.9 kg/cm(2)). PMID- 4148752 TI - Physiological types and histochemical profiles in motor units of the cat gastrocnemius. AB - 1. A variety of physiological properties of single motor units have been studied in the gastrocnemius muscle (primarily in the medial head) of pentobarbitone anaesthetized cats. Intracellular stimulation of individual motoneurones ensured functional isolation of the muscle units innervated by them.2. A system for muscle unit classification was developed using a combination of two physiological properties. Almost all of the units studied could be classified into one of three major types, including two groups with relatively short twitch contraction times (types FF and FR, which were differentiable from one another on the basis of sensitivity to fatigue) and one group with relatively long contraction times (type S, which were extremely resistant to fatigue and were differentiable from FF and FR units on the basis of the shape of unfused tetani). Post-tetanic potentiation of twitch responses was observed in all three muscle unit types. The distributions of axonal conduction velocities for motoneurones innervating FF and FR muscle units were essentially the same, while conduction velocities for motoneurones innervating type S units were, in general, slower.3. Histochemical profiles of muscle units representative of each of the physiological classes present in the gastrocnemius pool were determined using a method of glycogen depletion for muscle unit identification. Each of the physiological categories of muscle units exhibited a corresponding unique set of muscle fibre staining reactions, or histochemical profile. Within each physiological type, all of the units examined had the same histochemical profile. The results generally support the hypothesis that the histochemical characteristics of muscle fibres are meaningfully related to the physiological properties of the same fibres. However, certain limitations in the detailed application of the hypothesis were also apparent.4. Systematic assessment of the histochemical profiles of relatively large numbers of fibres belonging to single muscle units provided strong support for the hypothesis that all of the muscle fibres innervated by a single alpha motoneurone are histochemically identical. PMID- 4148754 TI - New concepts in asthma. PMID- 4148755 TI - [Clinical results of systemic and the new local administration form of Bayro Vas]. PMID- 4148756 TI - [New viewpoints on the effect of beta-receptor blockaders]. PMID- 4148757 TI - An MMPI scale to measure scholastic personality in women. PMID- 4148759 TI - Recovery from chronic idiopathic bone marrow aplasia of a young mother after intravenous injection of unprocessed cells from the liver (and yolk sac) of her 22 mm CR-length embryo. A preliminary report. PMID- 4148758 TI - Submicrosomal distribution of hepatic drug-metabolizing components in the Gunn rat. PMID- 4148760 TI - Isolation of acetyl CoA apocarboxylase by sepharose-avidin affinity chromatography. PMID- 4148761 TI - The function of ubiquinone in Klebsiella aerogenes. PMID- 4148762 TI - Maternal medication and its effect on the fetus. PMID- 4148763 TI - Transfer ribonucleic acid in hepatoma tissue culture cells. I. Induction in vivo by dexamethasone phosphate of phenylalanine-accepting activity. PMID- 4148764 TI - Effects of secretin on guanyl cyclase of various tissues. PMID- 4148765 TI - Mapping of the structural genes of the three aspartokinases and of the two homoserine dehydrogenases of Escherichia coli K-12. AB - Mutants requiring threonine plus methionine (or homoserine), or threonine plus methionine plus diaminopimelate (or homoserine plus diaminopimelate) have been isolated from strains possessing only one of the three isofunctional aspartokinases. They have been classified in several groups according to their enzymatic defects. Their mapping is described. Several regions of the chromosome are concerned: thrA (aspartokinase I-homoserine dehydrogenase I) is mapped in the same region as thrB and thrC (0 min). lysC (aspartokinase III) is mapped at 80 min, far from the other genes coding for diaminopimelate synthesis. metLM (aspartokinase II-homoserine dehydrogenase II) lies at 78 min closely linked to metB, metJ, and metF. PMID- 4148766 TI - Letter: Beta receptors and renin release. PMID- 4148767 TI - Purulent pericarditis: a review of diagnostic and surgical principles. PMID- 4148768 TI - [Treatment of patients with stenocardia associated with autonomic crises]. PMID- 4148769 TI - A demonstration of vagal adrenergic vascular and motor influences in the small intestine of the dog. PMID- 4148770 TI - [Lability and evolutionary conservatism of heat resistance of the body, cells and proteins of poikilothermic animals during changes in surrounding temperatures]. PMID- 4148771 TI - Sympathectomy and pharmacological blockade in trained rats. PMID- 4148772 TI - Tension perception in patients having pain associated with chronic muscle tension. PMID- 4148773 TI - Active unit of D-amino acid oxidase from hog kidney. PMID- 4148774 TI - [Adrenergic beta receptor blockaders. IV. 1-(Hydroxy- or dihydroxyphenoxy)-3 isopropylamino-2-propanols]. PMID- 4148775 TI - Cytochemical and pharmacological studies on polysensory neurons in the primate frontal cortex. PMID- 4148776 TI - Two male sibs with uterus and Fallopian tubes. A rare, probably inherited disorder. PMID- 4148777 TI - Dystonic reactions to drugs. PMID- 4148778 TI - [Preventive individual care of children with cleft lip and palate]. PMID- 4148779 TI - Mitogenic properties of the thymus-independent antigen pneumococcal polysaccharide S3. PMID- 4148780 TI - Conversion of glutamic acid to glutamine by retinal glutamine synthetase. PMID- 4148781 TI - The time course of pacemaker inhibition in the hydroid Tubularia. PMID- 4148782 TI - Patterns of transcription in Bacillus subtilis during sporulation. PMID- 4148783 TI - Activation of leukemia viruses by graft-versus-host and mixed-lymphocyte-culture reactions: electron microscopic evidence of C-type particles. PMID- 4148784 TI - Tumor growth and disulfide reduction: possible dependence on protein-disulfide reductase. PMID- 4148785 TI - Prolonged diarrhoea in a child with severe combined immunodeficiency. PMID- 4148786 TI - QtU-abnormalities, sinus bradycardia and Adams-Stokes attacks due to ventricular tachyarrhythmia. PMID- 4148787 TI - New drug development--expectations and speculations. PMID- 4148789 TI - Renal vascularity in the dog--alpha-adrenergic blockade and acute hemorrhage. PMID- 4148788 TI - Drug effects on pre- and post-branchial blood pressure and heart rate in a free swimming marine teleost, Gadus morhua. PMID- 4148790 TI - Detection of oxidases on polyacrylamide gels. PMID- 4148791 TI - [Subastragalar luxation]. PMID- 4148792 TI - [Betadrenol influence on cardiovascular and metabolic behavior in oral surgery with local anesthesia]. PMID- 4148793 TI - [Qualitative problems in analgesia by combined administration of beta-adrenolytic substances with local anesthetics]. PMID- 4148794 TI - Effects of propranolol and a new 'cardioselective' beta-blocker, H 93-26, on responses of isolated rat atria to isoprenaline and noradrenaline. PMID- 4148795 TI - Effects of isoetharine on airways resistance, heart rate, and contractions of the soleus muscle of the anaesthetised cat. PMID- 4148796 TI - [Hyperinsulinism and polyendocrine adenomatosis]. PMID- 4148797 TI - The interpretation of findings in clinical caries trials. PMID- 4148798 TI - Synthesis of cephapirin and related cephalosporins from 7-(alpha bromoacetamido)cephalosporanic acid. PMID- 4148799 TI - Symptomatic treatment of adults with bronchial asthma. PMID- 4148800 TI - Rhinitis. PMID- 4148801 TI - Letter: Pneumococcal typing sera. PMID- 4148803 TI - Sources of leukocytic endogenous mediator in the rat. PMID- 4148802 TI - [Usefulness of determination of enzymes unconnected with the digestive process in gastric juice]. PMID- 4148804 TI - [Value of congestive enzymes in liver and biliary tract diseases]. PMID- 4148805 TI - Perturbation of growth and metabolism in Candida albicans by 4-bromobenzyl isothiocyanate and iodoacetate. PMID- 4148806 TI - Stimulation of ovulation with F-6066 cyclofenil: bis-(p-acetoxyphenyl) cyclohexylidenemethane. PMID- 4148807 TI - Translation. XO-XY mosaics: six case studies. PMID- 4148808 TI - Effects of diphenylhydantoin upon estrogen metabolism by liver microsomes of DDT treated Japanese quail. PMID- 4148809 TI - Thiol-protein disulfide oxidoreductase activity in lactating and non-lactating mouse mammary gland. PMID- 4148810 TI - Stimulation of intestinal adenyl cyclase by Escherichia coli enterotoxin: comparison of strains from an infant and an adult with diarrhea. PMID- 4148811 TI - Acidaemia produced by spinal stimulation in the pithed rat. AB - 1. Electrical stimulation of the thoraco-lumbar spinal nervous outflow in the pithed rat preparation produces a fall in arterial blood pH.2. A component of the acidaemic response results from stimulation of skeletal muscle, since the acidaemic response is reduced when contractions of muscle are blocked with gallamine.3. The residual acidaemic response in gallamine-treated rats is reduced by adrenalectomy, suggesting that catecholamines liberated from the adrenal medulla may mediate part of the effect.4. Guanethidine reduces the acidaemic response remaining in adrenalectomized, gallamine-treated rats, suggesting that the effect of noradrenaline released from sympathetic nerve endings contributes to the fall in pH.5. Neither phenoxybenzamine nor propanolol alone significantly reduces the acidaemic response in gallamine-treated rats, but a combination of the two antagonists almost abolishes the effect. Hence the acidaemia is mediated through effects of catecholamines on both alpha- and beta-adreno-receptors.6. Since acidaemia affects responses to sympathetic nerve stimulation and sympathomimetic amines, the significance of these observations is discussed with reference to the use of the pithed rat preparation for assessment of drugs affecting adrenergic mechanisms. PMID- 4148812 TI - [Clinical evaluation of analeptics]. PMID- 4148813 TI - Studies on the function of cell membrane. 2. Elevation of NADH-cytochrome c reductase activity in the liver cell membrane of rats following CCl4 administration. PMID- 4148814 TI - Studies on the function of cell membrane. 3. On the purity of liver cell membrane fraction isolated from CCl4-treated rats. PMID- 4148815 TI - Studies on the function of cell membrane. 5. Characterization of NADH-cytochrome c reductase of liver cell membrane in normal and CCl4-treated rats. PMID- 4148816 TI - Pharmacological properties of electrical activities obtained from neurons in Auerbach's plexus. PMID- 4148817 TI - Antihistaminic and spasmolytic effects of musk. PMID- 4148818 TI - Effect of histamine, bradykinin and morphine on adrenaline release from rat adrenal gland. PMID- 4148819 TI - Analysis of contractions induced by transmural stimulation in the isolated sphincter of Oddi. PMID- 4148820 TI - Dissociation of stimulatory and synthetic phases in the induction of tyrosine hydroxylase. PMID- 4148822 TI - Animal health. PMID- 4148821 TI - Retinal structure in Latimeria chalumnae. PMID- 4148823 TI - Substitute foods-a practical alternative? PMID- 4148824 TI - Functional morphology with particular reference to hinge and ligament in Spondylus and Plicatula and a discussion of relations within the superfamily Pectinacea (Mollusca: Bivalvia). PMID- 4148825 TI - The biomass and distribution of organisms in Lake George, Uganda. PMID- 4148826 TI - 32-Msec scan of the NAD(P)H fluorescence spectrum in single living cells. PMID- 4148827 TI - [Effects of Combelen, Vetranquil, atropine, Pentothal and Fluothane on hematocrit, erythrocyte count, hemoglobin and mean corpuscular hemoglobin concentration in the horse]. PMID- 4148828 TI - [Symposium of "releasing factors"]. PMID- 4148829 TI - [Histogenesis and chemical differentiation of the trigeminal ganglion in the chick embryo]. PMID- 4148830 TI - Influence of the cell surface lipopolysaccharide structure of Salmonella typhimurium on resistance to intracellular bactericidal systems. PMID- 4148831 TI - The effect of acute and chronic methadone treatment on the in vitro N demethylation of methadone by microsomal enzymes of male and pregnant and nonpregnant female rats. PMID- 4148832 TI - Prevention of serotonin abortion by serotonin antagonists in rats. PMID- 4148833 TI - Comparative effects of sotalol and propranolol on myocardial contractility. PMID- 4148834 TI - Selective beta blockade of isolated rabbit detrusor muscle with practolol (AY21,011) and N-isopropylmethoxamine. PMID- 4148835 TI - Effect of isoprenaline on the response of the rabbit ear artery to electrical stimulation. PMID- 4148836 TI - Pathogenesis of the graft-versus-host reaction in chicken embryos. Requirement of yolk sac-derived stem cells for the development of proliferative lesions. PMID- 4148837 TI - [Enzymatic degradation of bromine urea derivatives in the liver]. PMID- 4148838 TI - [Alcoholic fatty liver from the standpoint of forensic medicine]. PMID- 4148839 TI - [Participation of autoimmunity in post-vaccination disorders of the CNS in children]. PMID- 4148840 TI - [Catecholamines and catecholamine synthesizing enzymes]. PMID- 4148841 TI - Inhibition by acetamidophenol of the production of prostaglandin-like material from blood platelets in vitro in relation to some in vivo actions. PMID- 4148842 TI - Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms. PMID- 4148843 TI - A possible mechanism of action of a central stimulant substance isolated from the sea anemone Stoichactis kenti. PMID- 4148844 TI - Vagally induced tachycardia in atropinized dogs: effect of beta-adrenergic blockade. PMID- 4148845 TI - Effects of a central stimulant substance isolated from the sea anemone Stoichactis kenti on brain monoamines of the mouse. PMID- 4148847 TI - Effects of histamine and pheniramine maleate on protease activity of sheep brain. PMID- 4148846 TI - Modification by enzyme-inducing drugs of the anticonvulsant action of phenytoin. PMID- 4148848 TI - Self-ratings of alienation in suicidal patients. PMID- 4148849 TI - A simple bivariate screening technique to separate NP hospital organics from other psychiatric groups. PMID- 4148850 TI - MMPI differentiation of multiple sclerosis vs. pseudoneurologic patients. PMID- 4148851 TI - Relationships among discharge variables and MMPI scale scores of hospitalized alcoholics. PMID- 4148852 TI - Race-related and educationally-related MMPI profile differences among hospitalized schizophrenics. PMID- 4148853 TI - Degree of agreement among MMPI scores, self-ratings, and staff ratings of inpatient adolescents. PMID- 4148854 TI - Application of the Midi-Mult to psychiatric inpatients. PMID- 4148855 TI - A comparison of the MMPI and Mini-Mult in a sample of state mental hospital patients. PMID- 4148856 TI - Development of a social desirability and acquiescence controlled Repression Sensitization Scale and some preliminary validity data. PMID- 4148857 TI - Emotional functions in short-term vs. long-term L-Dopa therapy in Parkinsonism. PMID- 4148858 TI - Loss of discriminative "power" of the MMPI with older psychiatric patients. PMID- 4148859 TI - Multimethod analysis of three measures of six common personality traits. PMID- 4148861 TI - [Extrathyroidal effect of methylmercaptoimidazole. II. Effect of methylmercaptoimidazole on the activity of the liver and kidneys of normal and thyroidectomized guinea pigs]. PMID- 4148860 TI - [Interpretation of the results of histochemical study of carbohydrate metabolism in the thyroid gland]. PMID- 4148863 TI - [ICN Congress demonstrates unity and interest for humanity]. PMID- 4148864 TI - [ICN's Congress in Mexico]. PMID- 4148865 TI - [National congress of the Norwegian Nurses' Association]. PMID- 4148862 TI - [Efficacy in the use of beta-adrenergic blockaders in the treatment of thyrotoxic disorders of the heart]. PMID- 4148866 TI - [Group report from delegates' meeting. I. Scandinavian Nurses' Association]. PMID- 4148868 TI - Single ectopic ureter in the male. PMID- 4148867 TI - Bladder exstrophy: vesicoplasty or urinary diversion? PMID- 4148869 TI - Effect of chronic treatment with ACTH on 11 beta-hydroxylation in rat adrenal mitochondria. PMID- 4148871 TI - [Studies on metabolism of bromourea derivatives. 1. In vitro degradation of carbromal and acetylcarbromal in rabbit liver]. PMID- 4148872 TI - [Respiratory insufficiency caused by beta-mimetics and aminophylline]. PMID- 4148870 TI - Postmortem bacteriology. 3. Clinical significance of microorganisms recovered at autopsy. PMID- 4148873 TI - [Effects of the new adrenergic beta receptor blockader Ko 1366 (Bunitrolol) on blood circulation]. PMID- 4148875 TI - Prevention of graft versus host reaction by incubation of lymphoid cells with a splenic extract (not affecting the repopulation of the haemopoietic tissue). PMID- 4148874 TI - The role of local-anesthetic effect in the inhibition of glycogenolysis in the liver of the rat. PMID- 4148876 TI - [Effects of phentolamine on cardiac contracitility in normal subjects studies with a polygraphic methods]. PMID- 4148877 TI - The effect of ethionine on the energy producing metabolism in the rat pancreas. 1. The influence on the activities of key enzymes of various metabolic pathways. PMID- 4148878 TI - An evaluation of new primary pediatric paraprofessionals. PMID- 4148879 TI - Letter: "That magnificent volume". PMID- 4148881 TI - Proceedings: The effect of an H2-receptor antagonist on histamine-stimulated acid secretion by rat stomach in vitro. PMID- 4148880 TI - The maturation of neuromuscular function in a multiply innervated structure: development of the longitudinal smooth muscle of the foetal mammalian gut and its cholinergic excitatory, adrenergic inhibitory, and non-adrenergic inhibitory innervation. AB - 1. The earliest components of the developing innervation of the rabbit intestine to be detected in this study were the cholinergic excitatory and the intrinsic inhibitory innervation. These developed simultaneously in the rabbit at 17 days of gestation. Both were also present in the mouse by the 16th day of gestation. Responsiveness of rabbit tissue to exogenous acetylcholine appeared together with the advent of a functional cholinergic innervation. Since excitatory responses were potentiated by eserine, the tissue was probably able to inactivate acetylcholine through hydrolysis mediated by cholinesterase. Early relaxant responses resisted blockade by adrenergic neurone blocking agents and by antagonists active at alpha- and beta-adrenoceptors.2. The development of the adrenergic innervation lagged far behind that of the other two components. Specific uptake of noradrenaline in the rabbit was detected for the first time at the 21st day of gestation and stores of noradrenaline could not be detected histochemically until 26-28 days. However, relaxant responses to stimulation of the perivascular sympathetic supply, such as characterize adult tissues, had not yet developed by the time of birth. Relaxation in response to perivascular stimulation could be seen 30 days after birth.3. Morphologic studies indicated that the longitudinal layer of smooth muscle was very primitive when an effective innervation was established. Although contractile, the cells were still myoblasts. Neural elements also appeared primitive. Thus considerable morphological maturation follows the development both of a functioning contractile machinery and innervation in the foetal gut.4. This study helps establish that the intrinsic inhibitory innervation of the gut is not adrenergic. PMID- 4148882 TI - The optimum time to operate for cryptorchidism. PMID- 4148883 TI - Kinetics of control enzymes. PMID- 4148884 TI - Pyridine nucleotides and rate control. PMID- 4148885 TI - Regulation of enzymes by covalent modification including hydrolysis of peptide bonds. PMID- 4148886 TI - The control of flux. PMID- 4148887 TI - Sex-linked abrogation of the graft-versus-host reaction. PMID- 4148888 TI - Prolongation of skin allograft survival with antilymphocyte serum and soluble histocompatibility antigens. PMID- 4148889 TI - Specific unresponsiveness to skin allografts in mice. II. The mechanism of unresponsiveness induced by tissue extracts and antilymphocytic serum. PMID- 4148890 TI - Mixed leukocyte culture reactivity and chronic graft-versus-host reactions (secondary disease) between allogeneic H-2k mouse strains. PMID- 4148891 TI - [Enzymatic parameters in diagnosis of fatty liver ]. PMID- 4148892 TI - The sensitivity of mycoplasmatales to sodium-polyanethol-sulfonate and digitonin. PMID- 4148893 TI - [Brown pigmentation (brown colour effect, BCE) of Cryptococcus neoformans on Guizotia abyssinica-creatinine-agar as dependent on the initial pH value (author's transl)]. PMID- 4148894 TI - [Fungistatic effect of carbonic acid-azides and alpha-azido-carbonic acids (author's transl)]. PMID- 4148895 TI - The role of fimbriae in the processes of infection. Preliminary report. PMID- 4148896 TI - [Neutralizing serum antibodies against calovo-virus among the population of South Germany (author's transl)]. PMID- 4148897 TI - [Studies on the activity and ecology of arboviruses in Turkey (author's transl)]. PMID- 4148898 TI - Influence of incubation temperaure on interferon mechanism in cells of Testudo graeca kidney. PMID- 4148899 TI - [The isolation of Salmonella from human faecal specimens in selenite enrichment medium at incubation temperature of 37 degress C 0r 43 degrees C (author's transl)]. PMID- 4148900 TI - Influence of sulfonamide antagonists on the synergism of sulfamethoxazole trimethoprim in Escherichia coli. PMID- 4148901 TI - [Double sugar iron agar with indication of aromatic amino acid deamination: a polytropic differentiating medium for enterobacteriaceae (author's transl)]. PMID- 4148902 TI - [Vibrio parahaemolyticus--enteropathogenicity, isolation, and identification (author's transl)]. PMID- 4148903 TI - [The occurrence of neuraminidase and acylneuraminate pyruvate-lyase in Corynebacterium haemolyticum and Corynebacterium pyogens (author's transl)]. PMID- 4148904 TI - Listeria monocytogenes-haemolysin: lecithinase. PMID- 4148905 TI - [Description of a modified technique for the determination of quality and concentration of influenza virus antibody molecules by means of equilibrium filtration and comparison of the efficiency of this technique to that of the conventional method (author's transl)]. PMID- 4148906 TI - The effect of NaCl on the morphology of listeria monocytogenes. PMID- 4148907 TI - [The taxonomic position of the species Mycob. aquae and Mycob. gordonae (author's transl)]. PMID- 4148908 TI - Urease as a useful criterion in the classification of microaerophilic actinomycetes. PMID- 4148909 TI - On the systematic position of microaerophilic, aerial mycelium forming actinomycetes of trutnov 139--66 typ. PMID- 4148910 TI - Significance of intermediary reduction products in the histochemical demonstration of dehydrogenase activity. PMID- 4148911 TI - Clinical experience with 19.552 R.P. in Nordic countries. PMID- 4148912 TI - Report of a conference on protein and amino acid needs for growth and development. PMID- 4148913 TI - Microbiological profiles of four Apollo spacecraft. AB - Selected surfaces from the Command Module, Lunar Module (ascent and descent stages), Instrument Unit, Saturn S-4B engine, and Spacecraft Lunar Module Adapter comprised the various components of four Apollo spacecraft which were assayed quantitatively and qualitatively for microorganisms. In addition, the first Lunar Roving Vehicle was assayed. Average levels of microbial contamination (10(4) per square foot of surface) on the Command Module, Instrument Unit, and Saturn S-4B engine were relatively consistent among spacecraft. The first postflight sampling of interior surfaces of the Command Module was possible due to elimination of the 21-day back-contamination quarantine period. Results of the pre- and postflight samples revealed increases in the postflight samples of 3 logs/inch(2). A total of 5,862 microbial isolates was identified; 183 and 327 were obtained from the Command Module at preflight and postflight sampling periods, respectively. Although the results showed that the majority of microorganisms isolated were those considered to be indigenous to humans, an increase in organisms associated with soil and dust was noted with each successive Apollo spacecraft. PMID- 4148914 TI - Activation of nitrate reductase from rice seedlings by NADH. PMID- 4148915 TI - Developmental characteristics of brain catecholamines and tyrosine hydroxylase in the rat: effects of 6-hydroxydopamine. AB - 1. Brain noradrenaline, dopamine and tyrosine hydroxylase were found in rat brain a few days before birth and increased progressively until reaching adult values. The most rapid period of growth for these substances seemed to occur between 7 and 18 days.2. The intracisternal administration of 6-hydroxydopamine to rats 7 days of age reduced concentrations of noradrenaline, dopamine, and tyrosine hydroxylase by 72 hours.3. The concentrations of noradrenaline, dopamine or tyrosine hydroxylase in rats that received 6-hydroxydopamine at 7 or 14 days of age remained markedly reduced when determined at adulthood, indicating that fibres did not continue to develop after the administration of this compound. The rats treated at 7 days also showed diminished concentrations of noradrenaline in heart.4. Rats injected with 6-hydroxydopamine at 7 days had reduced body weight as well as a reduction of some organ weights. This growth deficit was not observed in animals that received this drug at 14 days of age.5. The administration of ovine growth hormone to rats that received 6-hydroxydopamine at 7 days did not reverse the growth deficiency in these animals. PMID- 4148916 TI - Clinical investigation of an antagonist at alpha- and beta-adrenoceptors-AH5158A. AB - 1. The alpha- and beta-adrenoceptor blocking action of AH 5158A was investigated in man using the veins of the hand, the arterial bed of the forearm, and certain responses of the circulation as a whole.2. In the veins, locally infused AH 5158A resulted in specific and competitive antagonism of the constrictor response to locally infused noradrenaline and of the dilator response to isoprenaline.3. Brachial artery infusions of AH 5158A resulted in competitive antagonism of the arterial blood flow changes produced by local infusions of noradrenaline and isoprenaline.4. Systemic infusion of AH 5158A (0.5-0.9 mg/kg) produced clear blockade of the heart rate response to systemic infusion of isoprenaline. It also attenuated the response to exercise at 80 watts for 4 min; mean arterial pressure during exercise was reduced by 16% and heart rate by 18%. Blockade lasted at least 1 hour.5. AH 5158A caused small changes in arterial pressure and heart rate at rest supine, but had no effect on the response of pressure and rate to tilting. PMID- 4148917 TI - Comparison of blockade at alpha-adrenoceptors by thymoxamine and phentolamine in peripheral arteries and veins of man. AB - 1. The antagonism at alpha-adrenoceptors by thymoxamine and phentolamine of the response to noradrenaline was investigated in the limb veins and arteries of man.2. Brachial artery infusions of thymoxamine (40 mug/min) produced rises in resting arterial flow of up to 100%. When infused mixed with noradrenaline, thymoxamine (40 mug/min) attenuated the blood flow response to noradrenaline. Blockade was of a similar degree to that which occurred following a 10 min infusion of phentolamine (40 mug/min).3. Local intravenous infusion of thymoxamine (400-2,000 ng/min) mixed with noradrenaline attenuated the venoconstrictor response to noradrenaline. The degree of attenuation was similar to that seen after a 10 min infusion of phentolamine (500 ng/min). Blockade after thymoxamine did not last longer than 16 minutes. Neither thymoxamine nor phentolamine altered resting venous compliance.4. Local intravenous infusions of thymoxamine (500 ng/min) and phentolamine (500 ng/min) abolished the sympathetically mediated venoconstriction produced by overbreathing.5. Systemic injection of thymoxamine (0.1 mg/kg) did not block the reduction in forearm arterial flow produced by locally infused noradrenaline. In two out of three experiments, however, it produced some antagonism of noradrenaline induced venoconstriction. Systemic phentolamine (5 mg) blocked the effect of noradrenaline in the arterial bed, but antagonized its actions in the veins in only one out of three experiments. PMID- 4148918 TI - Interaction of atropine-like drugs with dopamine-containing neurones in rat brain. AB - 1. A variety of atropine-like drugs effective in the treatment of drug-induced extrapyramidal syndromes have been investigated with regard to their interaction with dopamine-containing neurones in rat brain.2. Under some conditions benztropine, trihexyphenidyl, atropine and ethopropazine significantly antagonized the chlorpromazine-induced increase in subcortical concentrations of homovanillic acid.3. Most of the atropine-like drugs investigated also decreased the turnover of dopamine in the subcortex as measured by following the disappearance of dopamine after administration of alpha-methyl-p-tyrosine.4. These findings are suggestive that an imbalance between a dopaminergic and cholinergic system might be closely linked to the pathogenesis of extra-pyramidal movement disorders. PMID- 4148920 TI - Proceedings: Failure to induce experimental hypertension in rats after intraventricular injection of 6-hydroxydopamine. PMID- 4148919 TI - Catecholamine concentrations and the activity of tyrosine hydroxylase after an increase in the concentration of tyrosine in rat tissues. AB - The concentrations of tyrosine in rat plasma and brain were increased 2-7 fold by the administration of either L-tyrosine or cycloheximide. Under these conditions catecholamine concentrations in the brain and the heart remained unchanged even when the rats were maintained in a cold environment to increase catecholamine turnover. The data are interpreted to mean that an increase in the tyrosine concentration in the tissues does not result in an in vivo substrate inhibition of tyrosine hydroxylase. PMID- 4148921 TI - Proceedings: Is thymoxamine a specific alpha-adrenoceptor blocking agent? PMID- 4148922 TI - Proceedings: Preliminary studies of Ro 3-3528, a beta-adrenoceptor-blocking agent, in man. PMID- 4148923 TI - Proceedings: Alpha-adrenoceptor inhibition from indoramin in man. PMID- 4148924 TI - Time course studies of glucose-induced changes in glucose-6-phosphate and fructose-1,6-diphosphate content of mouse and rat pancreatic islets. PMID- 4148925 TI - [Letter: Intravenous injections by nonphysicians]. PMID- 4148926 TI - [Caries prevention at Deszk by fluoridation of table salt. IX. Proportion of carious teeth in the upper and lower jaw during the past 5 years]. PMID- 4148927 TI - Alterations of hepatic enzyme activities in KK and yellow KK mice with various diabetic states. PMID- 4148928 TI - Effect of cortisol on the level of pyridoxal phosphate-dependent enzymes in the rat liver: new supports for antagonism between female sex hormones and cortisol. PMID- 4148929 TI - Cross reactions of a panosyl-azoprotein conjugate with antipneumococcal horse sera. PMID- 4148930 TI - Effect of school water fluoridation on dental caries: interim results in Seagrove, NC, after four years. PMID- 4148932 TI - 1,4-Benzodioxanes as reversible and irreversible antagonists at adrenergic receptors. PMID- 4148933 TI - 1-Alkylamino-3-(2-thiazolyloxy)-2-propanols. A novel class of mixed myocardial beta-stimulants-beta-blockers. PMID- 4148931 TI - Regulation of phosphoenolpyruvate carboxykinase and tyrosine transaminase in hepatoma cell cultures. 3. Comparative studies in H35, HTC, MH1C1 and RLC cells. AB - The ability of N(6), O(2)'-dibutyryl cyclic AMP (DBcAMP) to regulate a number of metabolic events in four lines of cultured rat hepatomas has been examined. Although dexamethasone induces tyrosine transaminase in all four lines, DBcAMP induces this enzyme normally only in H35 cells. A slight increase in transaminase activity was seen with MH(1)C(1) cells and HTC cells, but no effect was detectable in RLC cells. In contrast, phosphoenolpyruvate carboxykinase activity is increased by both agents in H35 and MH(1)C(1) cells, but neither had any effect in HTC or RLC cells. DBcAMP caused a rapid inhibition of the growth rate and DNA synthesis and an increase in protein content in both H35 and MH(1)C(1) cells but not in HTC or RLC cells. The effect of DBcAMP on DNA synthesis in MH(1)C(1) cells could be reversed by deoxycytidine as is also the case with H35 cells. The resistance of HTC and RLC cells to DBcAMP was not due to reduced uptake or deacylation as judged by studies with [(3)H]DBcAMP. The cyclic nucleotide appears to enter the cells by passive diffusion as the intracellular concentration approaches that in the medium within 30-60 min. Possible explanations for the differential responses observed are discussed. PMID- 4148934 TI - Blockade by burimamide of the effects of histamine and histamine analogs on cardiac contractility, phosphorylase activation and cyclic adenosine monophosphate. PMID- 4148935 TI - Effects of beta adrenergic blocking agents on plasma renin activity in the conscious rabbit. PMID- 4148936 TI - Protocols for physician assistants. Management of diabetes and hypertension. PMID- 4148938 TI - Responses of psychiatric inpatients to the MacAndrew Alcoholism Scale. PMID- 4148937 TI - Enzyme response to prednisolone and dibutyryl adenosine 3',5'-monophosphate in human fetal liver. PMID- 4148939 TI - Benzene metabolism in mouse liver microsomes. PMID- 4148940 TI - [Progress in diagnostic enzymology]. PMID- 4148942 TI - Hemodynamic and biochemical effects of a new positive inotropic agent. Antibiotic ionophore RO 2-2985. PMID- 4148941 TI - NAD and NADP dependent isocitrate dehydrogenase and fumarate hydratase activities in normal human skin and in some maculosquamous diseases of the skin. PMID- 4148943 TI - The use of computers in ambulatory care: lessons from 3000 encounters. PMID- 4148944 TI - Editorial: Computer application to biophysics in Russia. An editorial describing aspects of the Fourth International Biophysics Congress and personal observations on Russia. PMID- 4148945 TI - [Progress in the conservative treatment of angina pectoris]. PMID- 4148946 TI - Necrotizing angiitis: a report of two cases. PMID- 4148947 TI - Conservation of tissue specificity after heterotopic transplantation of gingiva and alveolar mucosa. PMID- 4148948 TI - MMPI characteristics of clergymen in counseling training and their relationship to supervisor's and peers' ratings of counseling effectiveness. PMID- 4148949 TI - Cross-validation of a system for predicting training success of Medex trainees. PMID- 4148950 TI - Personality characteristics of urban and suburban heroin abusers: more data and another reply to Sutker and Allain (1973). PMID- 4148951 TI - [Current trends in medical treatment of obliterating arteriopathies of the limbs]. PMID- 4148953 TI - [Various immunological aspects of the homotransplantation of the small intestine]. PMID- 4148952 TI - [Pharmacological explanation of dopamine (author's transl)]. PMID- 4148954 TI - Effects of convulsant and anticonvulsant drugs on the activity of some enzymes in the rat brain. PMID- 4148956 TI - [Participant in the All-Army Conference of the Active Members of the Armed Forces Medical Service]. PMID- 4148955 TI - [Aganon in the treatment of patients with allergic rhinosinusopathies]. PMID- 4148957 TI - [Therapeutic value of oxyphedrin (Ildamen) in treatment of ischemic heart disease]. PMID- 4148958 TI - [Preliminary studies on blood-sucking insects (Diptera-haematophaga) in the health resort Kolobrzeg and its environment]. PMID- 4148960 TI - [Arterial occlusion of the retina]. PMID- 4148959 TI - [Problems in ambulatory drug therapy. 4. Studies and human pharmacological aspects on ambulatory drug therapy of gastritis]. PMID- 4148961 TI - Certain aspects of drug binding to nonplasma proteins as illustrated by studies with cyclizine, chlorcyclizine, and polymyxin B. PMID- 4148962 TI - GVH-reactivity of rat lymphocytes sensitized in "mixed lymphocytes culture". PMID- 4148963 TI - [Effect of rhythmic stimulation of different modalities on mental work capacity]. PMID- 4148964 TI - [Clinical pharmacology of beta adrenergic blocking agents]. PMID- 4148965 TI - [Blood coagulation and fibrinolysis]. PMID- 4148966 TI - [The kidney in diseases of the rheumatic group]. PMID- 4148967 TI - [Role of angiographic examination in the diagnosis of periarteritis nodosa. A case with multiple aneurysms in the spleen and kidneys]. PMID- 4148968 TI - [Evaluation of methods for determining dehydrogenases and means of disintegrating the cells of Brevibacterium spl 22L in studying their activity]. PMID- 4148969 TI - Albumin transcapillary escape rate and plasma volume during long-term beta adrenergic blockade in essential hypertension. PMID- 4148971 TI - [Hyposensitization as causal therapy]. PMID- 4148970 TI - [Experience in the treatment of nonspecific ulcerative colitis]. PMID- 4148972 TI - [Hyposensitization. Theoretical and practical aspects. Panel discussion]. PMID- 4148973 TI - [Hyposensitization. Use--abuse]. PMID- 4148974 TI - [Effect of Anaprillin on the transport of electrolytes and hemodynamics]. PMID- 4148975 TI - [Reflections on the Congress for industrial protection and industrial medicine]. PMID- 4148976 TI - Metaproterenol, a potent and safe bronchodilator. PMID- 4148978 TI - Reaction of drugs with nitrous acid as a source of carcinogenic nitrosamines. PMID- 4148977 TI - Characterization of a peptidase from Diplococcus pneumoniae. PMID- 4148979 TI - Responses of plasma glucose, free fatty acids and glucagon to cobalt and nickel chlorides by Gallus domesticus. PMID- 4148980 TI - Responses of plasma glucose, free fatty acids, glucagon and insulin to synthalin A by Gallus domesticus. PMID- 4148981 TI - Investigations into the mode of action of synthalin A in Gallus domesticus. PMID- 4148982 TI - Studies on the adaptation of Xenopus laevis to hyperosmotic media. PMID- 4148983 TI - Extra-branchial pathways of salt exchange in a teleost fish. PMID- 4148984 TI - Hyperthermia in heat-adapted female rats. PMID- 4148985 TI - Oxygen dissociation and content of blood from Alaskan burbott (Lota lota), pike (Esox lucius) and grayling (Thymallus arcticus). PMID- 4148986 TI - Influence of exogenous growth hormone and its antiserum on plasma free fatty acid level in the pigeon. PMID- 4148987 TI - Seasonal variations and osmoregulation in the red blood cells of the diamondback terrapin Malaclemys centrata centrata (Latreille). PMID- 4148988 TI - Some aspects of the hematology and immunology of the hibernating and nonhibernating woodchuck (Marmota monax). PMID- 4148989 TI - The circannual variations of some of the hormones of the woodchuck (Marmota monax). PMID- 4148990 TI - Intestinal disaccharidase activity of non-human primates. II. Lorisidae, Hapalidae, Cebidae. PMID- 4148991 TI - The importance of the counter current oxygen multiplier mechanism in maintaining retinal function in the teleost. PMID- 4148992 TI - Hemoglobin of the aquatic salamander, Cryptobranchus. PMID- 4148993 TI - A study of some blood constituents of two species of mudfish. PMID- 4148994 TI - Diurnal rhythm in serotonin of blood and pineals of chickens. PMID- 4148995 TI - Geographic variation of thermal conductance in the house sparrow Passer domesticus. PMID- 4148996 TI - Water and salt regulation in the antelope ground squirrel (Ammospermophilus leucurus). PMID- 4148997 TI - Pineal gland: evidence for an influence on ethanol preference in male Syrian hamsters. PMID- 4148998 TI - In vitro blood carbon dioxide of the rainbow trout (Salmo gairdneri). PMID- 4148999 TI - Seasonal variations and the effects of nesting and moulting on liver mineral content in the mouse sparrow (Passer domesticus L.). PMID- 4149000 TI - The effects of hibernation on the chemical composition of cerebrospinal and intraocular fluids, blood plasma and brain tissue of the woodchuck (Marmota monax). PMID- 4149001 TI - "Hepatopancreas"? PMID- 4149002 TI - Effects of hypophysectomy on osmoregulation in the euryhaline flounder, Platichthys flesdus (L.), in sea water and in fresh water. PMID- 4149003 TI - Intestinal absorption of D-glucose and D-galactose in rats infected with Nematospiroides dubius. PMID- 4149004 TI - The effects of restricting gaseous exchange across the eggshell on the pO2, pCO2 and pH values of the extraembryonic fluids of the chick embryo. PMID- 4149005 TI - Conductive heat loss to sand in California sea lions and a harbor seal. PMID- 4149006 TI - O2 consumption and K+-Na+ balance of elasmobranch kidney slices after replacement of urea by thiourea or acetamide. PMID- 4149007 TI - The effects of artificial radiation on energetics of the eastern chipmunk, Tamias striatus. PMID- 4149008 TI - Effects of salmon gonadotropin on ovulation in the ayu, Plecoglossus altivelis, with special reference to water balance. PMID- 4149009 TI - Biliary excretion of insulin in the adult chicken. PMID- 4149010 TI - Biochemical responses elicited in normal or prolactin-treated Xenopus laevis (Daudin) specimens by environmental changes. PMID- 4149011 TI - FSH content of the anterior pituitary and the incorporation of L-lysine-U-14C into testicular proteins of heat-acclimatized rats. PMID- 4149012 TI - The size and shape of erythrocytes in the herring Clupea harengus L. PMID- 4149013 TI - Antidiuretic hormone and water conservation in desert rodents. PMID- 4149014 TI - The adrenal cortex and water conservation in desert rodents. PMID- 4149015 TI - Normal electrocardiogram of the chicken: its variations during vagal stimulation and following vagotomies. PMID- 4149016 TI - Field studies of hearing in two species of flatfish Pleuronectes platessa (L.) and limanda limanda (L.) (family pleuronectidae). PMID- 4149017 TI - Letter: Recordings of saccular microphonic potentials in the perch. PMID- 4149018 TI - Letter: Active sodium transport: a source of metabolic heat during cold adaptation in mammals. PMID- 4149019 TI - Seasonal effects of dehydration in air on urea production in the frog Rana pipiens. PMID- 4149020 TI - Behavioral regulation of internal temperature in the brown bullhead, Ictalurus nebulosus. PMID- 4149021 TI - Natural daily temperature acclimation of eastern red efts, Notophthalmus v. viridescens (Rafinesque) (Amphibia: Caudata). PMID- 4149022 TI - Correlation of tissue water content with lymphatic structure in toad and turtle bladders. PMID- 4149023 TI - Input characteristics of the intrinsic cells of the optic tectum of teleost fish. PMID- 4149024 TI - Comparison of endocrine function in normal and genetically athymic mice. PMID- 4149025 TI - [Beta adrenergic agents as labor inhibitors]. PMID- 4149026 TI - Modification of 1-tyrosine-induced keratopathy by adrenal corticosteroids. PMID- 4149027 TI - Pseudoisozymes of hepatic tyrosine aminotransferase. PMID- 4149028 TI - Effects of ready-to-eat breakfast cereals on dental caries experience in adolescent children: a three-year study. PMID- 4149029 TI - Ampicillin compared with penicillin and chloramphenicol combined in the treatment of bacterial meningitis. PMID- 4149030 TI - Zollinger-Ellison syndrome. Clinical features and long-term follow-up. PMID- 4149031 TI - Regional variation in capillary permeability of ventricular myocardium. PMID- 4149032 TI - Effect of prolonged isolation on learning, biogenic amine turnover and aggressive behaviour in three strains of mice. PMID- 4149033 TI - Tarsal tunnel syndrome. PMID- 4149034 TI - Cardiovascular function in the mammalian foetus. PMID- 4149036 TI - Laboratory models in filariasis: a review of filarial life-cycle patterns. PMID- 4149035 TI - [Treatment of angina pectoris with beta-receptor blockaders a slow-releasing isosorbide dinitrate preparation]. PMID- 4149037 TI - Mosquito light trap surveys in Korea 1969-1971. PMID- 4149038 TI - The effect of dopamine and noradrenaline antagonists on amphetamine induced locomotor activity in mice and rats. PMID- 4149040 TI - Fatal pneumonia presenting as transient neonatal tachypnea. PMID- 4149039 TI - [Beta blockaders and their therapeutic use in cardiology]. PMID- 4149041 TI - [Meeting of pediatric nurses on September 20, 1973 in Nurnberg. Opening address and introduction]. PMID- 4149042 TI - Allosteric modulation of the transient kinetics of carboxytryptophan oxygenase complex formation after laser flash photolysis. PMID- 4149043 TI - Crotonyl coenzyme A reductase activity of bovine mammary fatty acid synthetase. PMID- 4149044 TI - Regulation of glutamine synthetase from Bacillus subtilis by divalent cations, feedback inhibitors, and L-glutamine. PMID- 4149045 TI - Anesthetic-induced malignant hyperpyrexia in children. PMID- 4149046 TI - [ICN Congress in Mexico. My impressions from the 15th Congress]. PMID- 4149047 TI - Visit to Mexico, 1973. PMID- 4149048 TI - Editorial: Progress and problems in emergency medical care. PMID- 4149049 TI - The cerci and abdominal giant fibres of the house cricket, Acheta domesticus. II. Regeneration and effects of chronic deprivation. PMID- 4149050 TI - Changes in microbody-marker enzymes during growth of Tetrahymena pyriformis E. PMID- 4149051 TI - The determinants of growth and form. PMID- 4149052 TI - Thermochemical studies of human red blood cells: enthalpy changes on dilution in buffers. PMID- 4149053 TI - The cerci and abdominal giant fibres of the house cricket, Acheta domesticus. I. Anatomy and physiology of normal adults. PMID- 4149054 TI - Address of the president Sir Alan Hodgkin, O.M. at the Anniversary Meeting, 30 November 1973 (Thomas Young). PMID- 4149055 TI - [The husband's share in a sterile marriage]. PMID- 4149056 TI - The founding of the Scandinavian Rheumatological Society and the early history of the European League Against Rheumatism. PMID- 4149057 TI - In vitro on an HCG responsive, testosterone secreting adrenal cortical adenoma. PMID- 4149058 TI - [Nursing is for mankind and not only for patients]. PMID- 4149059 TI - [A model of the action of beta-mimetic substances (author's transl)]. PMID- 4149060 TI - [The treatment of late abortion and of threatened premature birth with Th 1165 a combined with Isoptin (author's transl)]. PMID- 4149061 TI - [Effects of prolonged inhibition of labour pains with Th 1165a and Isoptin on the heart, circulation, organ- and metabolic parameters of the mother (author's transl)]. PMID- 4149062 TI - [Serum glucose and immunoreactive insulin during or without treatment with Th 1165a und Isoptin in gravid women (author's transl)]. PMID- 4149063 TI - [Clinical experience with a treatment of threatened premature delivery with the aid of a beta-mimetic drug (author's transl)]. PMID- 4149064 TI - Review of the original chemical research into psychotropic agents in Czechoslovakia. PMID- 4149065 TI - Mucosal biopsy in ulcerative colitis for evaluating topical hydrocortisone therapy. PMID- 4149067 TI - A new enzymic assay for human deficiencies of coenzyme Q10. PMID- 4149066 TI - Effects of leucine and isoleucine on nicotinamide nucleotides of erythrocytes. PMID- 4149068 TI - The ecology of Whataroa virus, an alphavirus, in South Westland, New Zealand. AB - The findings of a survey on the ecology of an alphavirus over the years 1964-9 are reviewed. Evidence is presented to show that wild birds constitute a vertebrate reservoir of the virus and that mosquitoes, primarily Culiseta tonnoiri and Culex pervigilans, which are both endemic New Zealand species, are responsible for summer transmission.Serological evidence of infection was obtained in all years and evidence is presented to indicate that the virus is enzootic rather than being reintroduced each spring. The number of birds with antibody increased before mosquitoes became active in the spring and possible explanations of this are discussed.The mean temperature in the hottest month in the study area is substantially below that in other areas with enzootic mosquito borne viruses and experimental studies showed that Whataroa virus was able to replicate more rapidly in mosquitoes at low temperatures than any arboviruses previously studied.The main natural focus of infection appeared to be in a modified habitat and the introduced song thrush (Turdus philomelos) to be the main vertebrate reservoir host. PMID- 4149070 TI - The cariostatic effectiveness of a phosphate-fluoride gel administered annually to school children; final results. PMID- 4149069 TI - Studies on the microbial flora in the air of submarines and the nasopharyngeal flora of the crew. AB - Airborne bacteria surveys in nuclear submarines show that the total microbial load was maintained at satisfactorily low levels during prolonged patrols despite factors which were expected to increase this form of pollution.The isolation rates of Staphylococcus aureus and Neisseria meningitidis from nasal and nasopharyngeal swabs respectively, together with the serum antibody titres to Mycoplasma pneumoniae, before and after patrols suggested that the transmission of these organisms between individuals was not much increased by patrol conditions. The finding of higher numbers of airborne gram-negative rods and bodily contamination by enterobacteria is frequently reported in submersibles but does not appear to cause major outbreaks of illness in nuclear submarine crews. PMID- 4149071 TI - Two-year evaluation of a self-administered procedure for the topical application of acidulated phosphate-fluoride; final report. PMID- 4149073 TI - Clinical experiences in the management of cold injuries: a study of 110 cases. PMID- 4149072 TI - Carnitine and glycerylphosphorylcholine in the reproductive tract of the male rat. PMID- 4149074 TI - [Effect of meteorologic factors on healthy persons]. PMID- 4149075 TI - [Check-up programs for the geriatric practice?]. PMID- 4149076 TI - [Australia-(SH) antigen in medical expert testimony]. PMID- 4149077 TI - [Prognosis of hemiplegia and rehabilitation potential of the hemiplegic]. PMID- 4149078 TI - [Dipsomania and suicide]. PMID- 4149079 TI - [Prognosis of neurotic-psychopathic conditions]. PMID- 4149080 TI - [Medical importance of mosquitoes (Culicidae, Diptera) from the fauna of the Soviet Union]. PMID- 4149081 TI - [Parasitic fungus Coelomomyces sp. in the mosquito larvae in Mariiskaia ASSR]. PMID- 4149082 TI - [Experiences with depot-neuroleptics in an after-care unit. Organization of the therapy exemplified with pipotiazine palmitate]. PMID- 4149083 TI - Latest advances in diagnostic urologic radiology. I. Magnification renal arteriography. PMID- 4149084 TI - Urogenital anomalies and congenital rubella syndrome. PMID- 4149085 TI - Clinical evaluation of an oral combined antihistaminic sympathomimetic preparation. PMID- 4149087 TI - Serological investigations as applied for epidemiological evaluation of the population at a given area. PMID- 4149086 TI - A controlled clinical comparison of Lunerin and Rinomar in allergic rhinitis. PMID- 4149088 TI - Effects of chronic treatment with histamine on catecholamine content and synthesis in rat brain, heart and adrenals. PMID- 4149089 TI - Effects of morphine, in vitro and in vivo, on thyrosine hydroxylase activity in rat brain. PMID- 4149090 TI - Biochemical studies on the effect of papaverine on polymorphonuclear leucocytes. PMID- 4149091 TI - [Periarteritis nodosa of the brain]. PMID- 4149092 TI - [Effects of habitual chewing of sugar cane on caries incidence and periodontal condition of Cuban sugar cane workers]. PMID- 4149093 TI - [Therapy recommendations in the field of pedodontics: therapy of caries in the deciduous tooth]. PMID- 4149094 TI - [Neurohumoral pathways of hypothalamic influences in experimental stomach and duodenal ulcer]. PMID- 4149095 TI - Talc embolism: sudden death following intravenous injection of phenyltoloxamine. PMID- 4149097 TI - Medicine accepts another challenge. PMID- 4149096 TI - [Measures for relieving the overwork of students in the People's Republic of Bulgaria]. PMID- 4149098 TI - Foreign trained physicians in Illinois. PMID- 4149099 TI - Headache associated with low spinal fluid pressure syndrome. (Primary intracranial hypotension). PMID- 4149100 TI - The treatment of accessible malignant tumors by irradiation. PMID- 4149101 TI - Allergic aspergillosis in a family. PMID- 4149102 TI - Surgical grand rounds: Radiation enteritis. PMID- 4149103 TI - Prevention of accidental falls in infancy by counseling mothers. PMID- 4149104 TI - Visceral larva migrans. PMID- 4149105 TI - Measles in suburban Cook County. PMID- 4149106 TI - View box: bezoars occurring in a gastric remnant after a gastrectomy. PMID- 4149107 TI - Diagnostic patterns in disability in Illinois and the nation. PMID- 4149108 TI - EKG of the month. Bundle-branch block. PMID- 4149109 TI - Guest Editorial: The peril of "non-peer peer review". PMID- 4149110 TI - Rift Valley fever. 3. Viraemia in cattle and sheep. 4. The susceptibility of mice and hamsters in relation to transmission of virus by mosquitoes. PMID- 4149111 TI - [Effect of aminazin and droperidol on cerebral circulation and its regulation]. PMID- 4149112 TI - [Experience in the treatment of hypertensive states with beta-blockaders]. PMID- 4149113 TI - [Transferase activity of glutamine synthetase from the food yeast Candida tropicalis]. PMID- 4149114 TI - A possible proprioceptor in Ceriantheopsis americanus (Cnidaria, Ceriantharia). PMID- 4149116 TI - An exploratory psychological study of digestive diseases. PMID- 4149115 TI - [Effectiveness of treating coronary arteriosclerosis according to follow-up study data]. PMID- 4149117 TI - Side effects of antihypertensive drugs. PMID- 4149118 TI - The effect of acute hypoxia on cardiac dysrhythmias induced by mesencephalic stimulation. PMID- 4149119 TI - Gamma-glutamyl transpeptidase in cancer diagnosis. PMID- 4149120 TI - [Recent research on isoxazole-(3,4-d)-pyridazin-7-one derivatives]. PMID- 4149121 TI - Diseases of the skin. Drug ill effects on the skin. PMID- 4149122 TI - Response of leucocyte adenyl cyclase to isoprenaline and effect of alpha-blocking drugs in extrinsic bronchial asthma. AB - The finding by several workers that biochemical responses to catecholamines are diminished in asthmatic patients during periods of active asthma as compared to normal subjects has led to the recognition of the beta-adrenergic blockade phenomenon, a common accompaniment of extrinsic bronchial asthma. Using an intact cell method to measure leucocyte adenyl cyclase activity, we have been able to show that there is a noticeably reduced responsiveness of this enzyme system (which is now identified with beta-receptor function) to isoprenaline in the leucocytes of patients suffering from acute bronchial asthma, but that asthmatic patients in remission could not be distinguished from normal persons in this respect. Evidently the defective beta-receptor function may be associated with overactivity of the alpha-receptors in acute bronchial asthma, since the responsiveness to isoprenaline stimulation could be restored towards normal by concomitant treatment of the leucocytes of these patients with alpha-receptor blocking drugs such as phentolamine or thymoxamine. Ouabain, though somewhat less potent, also enhanced responsiveness to isoprenaline stimulation. The relation of these results to the clinical observation of adrenaline resistance in active asthma suggests that alpha-receptor blocking drugs may be of value in restoring the sensitivity of beta-receptors to sympathomimetic amines. PMID- 4149123 TI - Chemical modification of the crayfish neuromuscular junction. PMID- 4149124 TI - [Working capacity dynamics of pupils from the 5th to 7th grades during a school day (in accordance with new programs)]. PMID- 4149125 TI - Effect of experimental cryptorchism on testis L-iditol: NAD oxidoreductase (sorbitol dehydrogenase or ketose-reductase). PMID- 4149126 TI - Effects of beta-adrenergic blockade and stimulation on normal human airways. PMID- 4149127 TI - Hydrogen transfer from NADPH to steroid by testicular 20 alpha-hydroxysteroid dehydrogenase: stereospecficity and isotope effect. PMID- 4149128 TI - Beta adrenergic blockade on intramyocardial distribution of coronary blood flow. PMID- 4149129 TI - The mechanism of action of histamine on the isolated rat uterus. PMID- 4149130 TI - On the specificity of alpha adrenergic receptor labeling by 14C-dibenamine. PMID- 4149131 TI - Allied health manpower strategies: estimates of the potential gains from efficient task delegation. PMID- 4149132 TI - [Species composition of bloodsucking mosquitoes (Diptera, Culicidae) and their distribution according to topographical and climatic zones of Abkhazia]. PMID- 4149133 TI - Psychological prediction of leadership in nursing. PMID- 4149134 TI - A rhynchosaur from the Upper Triassic Maleri Formation of India. PMID- 4149135 TI - Equipment for clinical chemistry and its evaluation. PMID- 4149136 TI - Automated clinical chemistry and haematology in a hospital region. PMID- 4149137 TI - Advanced technology in the hospital laboratory: handling and interpreting multiple results. PMID- 4149138 TI - Computers and the organization of medical care. What computers can and cannot do. PMID- 4149139 TI - The Stockholm County Council's medical information system. PMID- 4149140 TI - Computer-based records in the clinic (a). PMID- 4149141 TI - Computer-based records in the clinic (b). PMID- 4149142 TI - Linked record medical information systems. PMID- 4149143 TI - The computing approach to clinical diagnosis. PMID- 4149144 TI - Surgical diagnosis assisted by a computer. PMID- 4149145 TI - Pattern recognition by computer. PMID- 4149146 TI - Automated e.c.g. interpretation in the National Health Service. PMID- 4149147 TI - A discussion on the value of automation in the health service. Advanced technology--research and the future. PMID- 4149149 TI - Biometric findings on cardiac neurosis. I. Character and clinical aspects of cardiac neurosis. PMID- 4149148 TI - [Course studies on cerebral glutamine excretion in schizophrenics under treatment with tranquilizing agents]. PMID- 4149150 TI - Biometric findings on cardiac neurosis. II. ECG and circulation findings of cardiophobic patients during standardized examination of the circulatory system. PMID- 4149151 TI - [Biometric findings in cardiac neuroses]. PMID- 4149152 TI - [Supersensitivity of early embryos of the sea urchin Arbacia lixula to neuropharmacological preparations]. PMID- 4149153 TI - [Effect of cholinolytic substances on giant neurons of the gastropod mollusc Planorbarius corneus]. PMID- 4149154 TI - The pressor effect of oxotremorine and arecoline in rats. PMID- 4149155 TI - [Melanoma and traumatism]. PMID- 4149156 TI - On the decarboxylation of alpha-keto acids by isolated chloroplasts. PMID- 4149157 TI - Energy conservation in membranes of mutants of Escherichia coli defective in oxidative phosphorylation. PMID- 4149158 TI - Metabolites of p-aminobenzoic acid. V. Isolation and properties of p-aminobenzyl alcohol dehydrogenase. PMID- 4149159 TI - Kinetic aspects of nitrate reductase from Cyanidium caldarium. Inhibition by reduced pyridine nucleotides. PMID- 4149160 TI - Kinetic analysis of partially purified glucose-6-phosphate dehydrogenases from rat muscle, adipose tissue and liver, and from baker's yeast. PMID- 4149161 TI - [Glutamate dehydrogenase. Modification of polyhexamers due to coenzymes and specific effective substances]. PMID- 4149162 TI - Nonspecific activity and habituation of tonic and phasic skin conductance in somatic complainers and controls as a function of auditory stimulus intensity. PMID- 4149163 TI - [Results of treatment of cryptorchism in children]. PMID- 4149164 TI - [Autoaggression process in experimental encephalitis]. PMID- 4149165 TI - [Ecological characteristics of species of bloodsucking mosquitoes in Central Chukot]. PMID- 4149166 TI - Measurements of serum L-alanine aminotransferase activity on the centrifichem and on the LKB 8600. PMID- 4149167 TI - Antagonism of histamine H2-receptors and gastric secretion. PMID- 4149168 TI - An observation about the relative hardiness of bacterial spores and planetary quarantine. PMID- 4149169 TI - [Drugs inhibiting uterine contractions]. PMID- 4149170 TI - [Drugs inhibiting contractions]. PMID- 4149171 TI - Orchidopexy using a Dartos pouch. PMID- 4149172 TI - Hepatic metabolic pattern in experimental nephrotic syndrome: glycolysis, gluconeogenesis, and amino acid metabolism. PMID- 4149173 TI - Nicotinamide coenzymes in heart and coronary blood during myocardial infarction. PMID- 4149174 TI - Beta-adrenergic blocking drugs in anaesthesia. PMID- 4149175 TI - Effeminate behavior in boys. Parental age and other factors. PMID- 4149176 TI - [Cells and matrix in orthotop-homotransplanted epiphyseal cartilage (author's transl)]. PMID- 4149177 TI - Histochemical study of gamma glutamyl transpeptidase (GGT) in experimental intrahepatic and extrahepatic cholestasis. PMID- 4149178 TI - Mechanism of electron transport and energy conservation in the site I region of the respiratory chain. PMID- 4149179 TI - Maternal and neonatal metabolism of analgesic drugs. PMID- 4149180 TI - Complications during physical rehabilitation of coronary patients, with comments on drug therapy. PMID- 4149181 TI - Characteristics of the catecholamine and histamine receptor sites mediating accumulation of cyclic adenosine 3',5'-monophosphate in guinea pig brain. PMID- 4149182 TI - Some factors affecting the uptake, binding and retention of (3H)cortisol by the chick embryo retina as related to enzyme induction. PMID- 4149183 TI - Amino acids as central nervous transmitters: the influence of ions, amino acid analogues, and ontogeny on transport systems for L-glutamic and L-aspartic acids and glycine into central nervous synaptosomes of the rat. PMID- 4149184 TI - Federation of Prosthodontic Organizations: Annual Session Report, 1973. PMID- 4149185 TI - Editorial: Sports medicine in modern times. A short historical survey. PMID- 4149186 TI - [The thyroid medullary carcinoma syndrome, pheochromocytoma and multiple mucosal neuromas. Case report]. PMID- 4149187 TI - [Histological investigations of cryptorchidism (author's transl)]. PMID- 4149188 TI - [Diseases of the gonads in childhood (author's transl)]. PMID- 4149189 TI - [Preliminary report on clinical, biochemical, and anatomical investigations of boys with undescended testes (author's transl)]. PMID- 4149190 TI - [State of the cardiac function and certain neuro-humoral mechanisms of its regulation in children and adolescents with primary arterial hypertension]. PMID- 4149191 TI - Studies on the role of adenosine 3',5'-monophosphate during glucose repression in rat liver. PMID- 4149192 TI - Thyroxine deiodination associated with NADPH-dependent (enzymatic) and Fe3+-ADP catalyzed (nonenzymatic) reactions in hepatic microsomes. PMID- 4149193 TI - Human neuroblastoma cell culture: effect of 5-bromodeoxyuridine on morphological differentiation and levels of neural enzymes. PMID- 4149194 TI - The genesis of the initial blood pressure peak following IV administration of certain catecholamines. PMID- 4149195 TI - [Mechanism of bronchial hyperexcitability]. PMID- 4149196 TI - [Treatment of asthma]. PMID- 4149197 TI - [Present ideas on the pathogeny and treatment of asthma: general conclusions]. PMID- 4149198 TI - The cardiovascular activity of 2-amino-5-(3,4-dichlorophenoxymethyl)-2-oxazoline (APMO). PMID- 4149199 TI - Chromosomal abnormalities in undescended testes. PMID- 4149200 TI - [Comparative characteristics of antiarrhythmic activity of certain drugs in patients with thyrotoxic auricular fibrillation]. PMID- 4149201 TI - [Effect of pirilen, dimecolin and isobarin on certain clinico-biochemical indicators in patients with hypertensive disease]. PMID- 4149202 TI - [Significance of leukocytosis, antihistamine factor and tuberculin hemolysis in the diagnosis of tuberculosis]. PMID- 4149203 TI - President's opening speech. PMID- 4149204 TI - Homogeneous antibodies: a probe for the problem of antibody diversity. PMID- 4149205 TI - [Immunosuppressive therapy in internal medicine]. PMID- 4149206 TI - [Treatment of respiratory distress in the framework of an internal medicine service]. PMID- 4149207 TI - Isoproterenol blockade in man; comparison between penbutalol and acebutolol. PMID- 4149209 TI - Mexico, 1973; International Council for Nurses May 13-19. 15th Quadrennial Congress. PMID- 4149210 TI - [International Council for Nurses May 13-19; Mexico 1973. 15th Quandrennial Congress]. PMID- 4149208 TI - [Betasympatholytics]. PMID- 4149211 TI - The pentose shunt in wild-type and glucose-6-phosphate dehydrogenase deficient Drosophila melanogaster. PMID- 4149212 TI - Effect of adenosine and some of its analogs on renal hemodyamics. PMID- 4149213 TI - [A time study of attending the child health conference in Taipei Public Health Teaching and Demonstration Center]. PMID- 4149215 TI - International Council of Nurses 15th Quadrennial Congress; Mexico 73. PMID- 4149216 TI - [Report on the ICN Council of national representatives]. PMID- 4149214 TI - Treatment of exotic parasitic diseases. PMID- 4149217 TI - [Next ICN Congress to be held in Japan]. PMID- 4149218 TI - [Polygraphic studies in subjects of different ages following a single dose of beta-adrenergic inhibitors]. PMID- 4149219 TI - Plasma corticosteroid levels in anaphylactic shock of guinea pigs. PMID- 4149220 TI - [Correlations between the results of pharmacokinetic and pharmacological studies on several pipotiazine esters]. PMID- 4149221 TI - [Disodium cromoglycate (Lomudal). Clinical actions, indications and practical use in asthmatic lung diseases]. PMID- 4149222 TI - [Why do beta blockaders depress blood pressure?]. PMID- 4149223 TI - [Beta-blockaders in hypertension]. PMID- 4149224 TI - [The adrenergic beta receptor in the heart. Isolation and identification]. PMID- 4149225 TI - [Letter: Beta blockaders yet again]. PMID- 4149226 TI - Ultrastructure of lymphoid cells involved in local graft-versus-host reaction. PMID- 4149227 TI - An electron microscope study of the delayed effects on rabbit spermateleosis following experimental cryptorchidism for twenty-four hours. PMID- 4149228 TI - A light microscope study of the immediate and delayed effects on rabbit spermatogenesis following experimental cryptorchidism for twenty-four hours. PMID- 4149229 TI - Testicular tumors. A retrospective study. PMID- 4149230 TI - Purification and properties of L-erythro-3,5-diaminohexanoate dehydrogenase from Clostridium sticklandii. PMID- 4149231 TI - Fluorescence and optical characteristics of reduced flavines and flavoproteins. PMID- 4149232 TI - Allogeneic marrow grafting for treatment of aplastic anemia. PMID- 4149233 TI - G-6-PD Manchester: a new variant associated with chronic nonspherocytic hemolytic anemia. PMID- 4149234 TI - Glucocorticoid and mineralocorticoid effects in rat liver and kidney. PMID- 4149236 TI - A double-blind investigation of dimethacrine versus imipramine in hospitalized depressive states. PMID- 4149235 TI - Action of fully co-ordinated 1,10-phenanthroline transition metal chelates on the guinea-pig isolated atrium. PMID- 4149237 TI - Heart rate after combined vagal and sympathetic blockade with atropine and different beta-receptor blocking agents. PMID- 4149238 TI - The correlation between bacteriological findings in the nose and maxillary sinus in acute maxillary sinusitis. PMID- 4149239 TI - Graft-versus-host disease after intrauterine and exchange transfusions for hemolytic disease of the newborn. PMID- 4149240 TI - Editorial: Trojan-horse lymphocytes. PMID- 4149241 TI - Letter: Undescended testis. PMID- 4149242 TI - The use of allogeneic freeze-dried skin grafts in the oral environment. A clinical and histologic evaluation. PMID- 4149243 TI - Kinetics of atropine and Diamox inhibition of histamine-stimulated gastric secretion. PMID- 4149244 TI - [Possible mechanism of regulation of the functions of mediators in the processes of pre-neural embryogenesis]. PMID- 4149246 TI - The ecology of streptococcus mutans in carious lesions and on caries-free surfaces of the same tooth. PMID- 4149245 TI - [Cardiovascular problems posed by space flights]. PMID- 4149247 TI - The effects of chronic phenobarbitone administration and subsequent withdrawal on the activity of rat liver tryptohan pyrrolase and their resemblance to those of ethanol. AB - Chronic phenobarbitone administration inhibits the apo-(tryptophan pyrrolase) activity in homogenates of rat liver and subsequent withdrawal enhances the enzyme activity by 2.5-fold. Similar effects have been previously produced by chronic ethanol administration and withdrawal, but, whereas NADH may cause the ethanol inhibition, that by phenobarbitone may be mediated by NADPH. PMID- 4149248 TI - Influence of fatty acid and sterol composition on the lipid phase transition and activity of membrane-bound enzymes in Acholeplasma laidlawii. PMID- 4149249 TI - The separation and enzymatic characterization of inner and outer membranes of rat heart mitochondria. PMID- 4149250 TI - [Partial characterization of a delta 4-3-ketosteroid-5-oxidoreductase in seminal vesicles of the anuran amphibian Discoglossus pictus]. PMID- 4149251 TI - Metabolic alterations in the axotomized superior cervical ganglion of the rat. I. Energy metabolism. PMID- 4149253 TI - Treatment of acute exacerbations of chronic bronchitis with clindamycin. PMID- 4149252 TI - Metabolic alterations in the axotomized superior cervical ganglion of the rat. II. The pentose phosphate pathway. PMID- 4149254 TI - Diurnal variation in the symptoms of hay fever: implications for pharmaceutical development. PMID- 4149255 TI - The use of mutants of Escherichia coli K12 in studying electron transport and oxidative phosphorylation. PMID- 4149256 TI - Characteristic serum glycoproteid curves in syngeneic and semiallogeneic skin transplantation in rats. PMID- 4149257 TI - [The radiological diagnosis of phaeochromocytoma with special reference to angiography and the specific preparation required (author's transl)]. PMID- 4149258 TI - The pattern of dental diseases in the Asian Area of the Pacific Basin. PMID- 4149259 TI - The pattern of dental disease in the South Pacific Area of the Pacific Basin. PMID- 4149260 TI - The prevention of dental caries by mouthrinsing with solutions of neutral sodium fluoride. PMID- 4149261 TI - Morphogenetic properties of the parts of the colony of Clytia johnstoni. PMID- 4149262 TI - Base composition of ribosomal RNA and evolution. PMID- 4149263 TI - Construction techniques for wrought-wire retentive clasp arms as related to clasp flexibility. PMID- 4149264 TI - [Treatment of Meniere's disease with ganglioplegic drugs]. PMID- 4149266 TI - Facial injuries in football. PMID- 4149265 TI - [Bronchoconstrictor effects of beta-adrenergic blockade in asthma: influence of baseline value (author's transl)]. PMID- 4149267 TI - The castration of horses: or castration of half a horse? PMID- 4149268 TI - [Nicotinamide nucleotide content and rate of synthesis of NADP in rabbit muscles during embryonal and postnatal development]. PMID- 4149269 TI - The diagnostic value of gamma-GT-estimations on blood samples collected in conjunction with exsanguination of cattle. PMID- 4149270 TI - Comparative susceptibility of eight mosquito species to Sindbis virus. PMID- 4149271 TI - Anesthetic uptake--of mice and men (and whales). PMID- 4149272 TI - Oscillations of enzyme activities during the cell-cycle of a glucose-repressed fission-yeast Schizosaccharomyces pombe 972h-. AB - 1. Increased specific activities of cytochrome c oxidase, catalase, succinate dehydrogenase, succinate-cytochrome c oxidoreductase, NADH-cytochrome c oxidoreductase and malate dehydrogenase were observed during glucose de repression of Schizosaccharomyces pombe. 2. The cell-cycle of this organism was analysed by three different methods: (a) harvesting of cells at intervals from a synchronous culture, (b) separation of cells by rate-zonal centrifugation into different size classes and (c) separation of cells by isopycnic-zonal centrifugation into different density classes. 3. Measurement of enzyme activities during the cell-cycle showed that all the enzymes assayed [cytochrome c oxidase, catalase, acid p-nitrophenylphosphatase, NADH-dehydrogenase, NADH cytochrome c oxidoreductase, NADPH-cytochrome c oxidoreductase, succinate dehydrogenase, malate dehydrogenase, isocitrate dehydrogenase (NADP) and fumarate hydratase] show periodic expression as ;peaks'. 4. Cytochrome c oxidase shows a single maximum at 0.67 of a cycle, whereas succinate dehydrogenase exhibits two maxima separated by 0.5 of a cell-cycle. 5. All other enzymes assayed showed two distinct maxima per cell-cycle; for catalase, malate dehydrogenase and NADPH cytochrome c oxidoreductase there is the possibility of multiple fluctuations. 6. The single maximum of cytochrome c oxidase appears at a similar time in the cycle to one maximum of each of the other enzymes studied, except for NADH dehydrogenase. 7. These results are discussed with reference to previous observations on the expression of enzyme activities during the cell-cycle of yeasts. PMID- 4149273 TI - Respiration-driven proton translocation in Escherichia coli. AB - Measurements were made of the stoicheiometry of respiration-driven proton translocation coupled to the oxidation of NAD(P)-linked or flavin-linked substrates in intact cells of Escherichia coli. Observed stoicheiometries (- >H(+)/O quotient; Mitchell, 1966) were approx. 4 with l-malate as substrate and approx. 2 for succinate, d-lactate and glycerol oxidation. It is concluded that the potential number of equivalent energy-conservation sites associated with the respiratory chain is 2 in aerobically grown cells of E. coli harvested during the exponential phase of growth. PMID- 4149274 TI - The inhibition of mitochondrial respiration by inhalational anaesthetic agents. PMID- 4149275 TI - Effect of vitamin A deficiency on protein catabolism in chicks. PMID- 4149276 TI - Microsomal drug-metabolizing enzyme activity in livers of bats. PMID- 4149277 TI - Biosynthesis of wax esters in cell-free preparations of Euchaeta norvegica. PMID- 4149278 TI - Androgen metabolism in rat testicular tissue. PMID- 4149279 TI - Effects of gonadotropins on cyclic AMP production by isolated seminiferous tubule and interstitial cell preparations. PMID- 4149280 TI - The degradation of CoA: subcellular localization and kinetic properties of CoA- and dephospho-CoA pyrophosphatase. PMID- 4149281 TI - Some properties of NADPH-cytochrome c reductase reconstitutively active in fatty acid omega-hydroxylation. PMID- 4149282 TI - [A new enzyme: the 2'-nucleotidase from latex of Hevea brasiliensis]. PMID- 4149283 TI - The role of cytochrome P-450 in cholesterol biosynthesis. PMID- 4149284 TI - D-galactose dehydrogenase from Pseudomonas saccharophila. Purification, properties and structure. PMID- 4149285 TI - Reduction of the acetyl coenzyme A carboxylase content of Saccharomyces cerevisiae by exogenous fatty acids. PMID- 4149286 TI - Does levodopa alter depression and psychopathology in Parkinsonism patients? AB - Twenty-seven Parkinsonism patients and 31 controls, matched for age and verbal IQ, were tested on an objectively scored personality test (Minnesota Multiphasic Personality Inventory) at the beginning of the patients' levodopa therapy and three months later. Patients, but not the controls, were retested after 15 months of levodopa treatment. The patients, all of whom were intact intellectually, obtained MMPI scores indicating moderate depression before beginning levodopa treatment. There was no test evidence to indicate that levodopa significantly increased or decreased the amount of depression in the patients after three or 15 months of levodopa. The patient group, however, significantly increased their Index of Psychopathology (Ip) score after 15 months of levodopa but not after three months. PMID- 4149289 TI - Hydroxyapatite formed from coral skeletal carbonate by hydrothermal exchange. PMID- 4149288 TI - The action of Bothrops neuwiedii phospholipase A2 on mitochondrial phospholipids and electron transfer. PMID- 4149291 TI - [The sale of psychoactive drugs and hypnotics in Sweden and Norway--based on dosage statistics]. PMID- 4149290 TI - Neurotransmitter synthetic enzymes. PMID- 4149292 TI - [Results of orthotopic homologous liver transplantation]. PMID- 4149293 TI - The fate of dieldrin in a model ecosystem. PMID- 4149294 TI - [Pindolol in foreign medical practice]. PMID- 4149296 TI - Stress, adrenocortical activity and sleep habits. PMID- 4149295 TI - Therapy of infections with parenteral cephalexin. PMID- 4149297 TI - Role of some biogenic substances in migraine and relevant mechanism in antimigraine action of ergotamine--studies in an experimental model for migraine. PMID- 4149298 TI - Immunochemical analysis of rabbit antibodies against vasopressin. PMID- 4149299 TI - Desaturation and saturation of fatty acids by sheep rumen bacteria: optimal conditions and cofactor requirements. PMID- 4149301 TI - The allergic reaction. Application of the new immunology. PMID- 4149300 TI - Feeding elicited by alpha and beta adrenoceptor agonists injected intrahypothalamically in sheep. PMID- 4149302 TI - Selective adrenergic stimulant actions of 1-isopropylamino-3-(2-thiazoloxy)-2 propanol (ITP) in anesthetized cats. PMID- 4149303 TI - [Adrenergic beta receptor blockaders in the treatment of mental disorders]. PMID- 4149304 TI - Hormonal mechanisms in regulation of gene expression. PMID- 4149305 TI - Inhibition of catecholamine synthesis during ontogenic development. PMID- 4149306 TI - Relationships between neurotransmitter metabolism and behaviour in seven inbred strains of mice. PMID- 4149307 TI - Neurotransmitter synthesis in the tectum of the tiger salamander Ambystoma tigrinum. PMID- 4149308 TI - Hemopoietic cell line-specific effects of renal granulopoietic factor (GPF) on transplantable mouse marrow stem cells: comparison with erythrocyte stimulating factor (ESF) and endotoxin. PMID- 4149309 TI - Propranolol and serum gastrin in postvagotomy insulin tests. PMID- 4149310 TI - Self-application of fluoride by rinsing. PMID- 4149311 TI - Weekly mouth-rinsing with 3000 ppm of fluoride; the effect of concentration of fluoride in the enamel. PMID- 4149312 TI - Editorial: The patient needs. PMID- 4149313 TI - On the graft-versus-host nature of the allogeneic effect in a tumor isograft system. PMID- 4149314 TI - Autoradiographic studies on small lymphocytes in rats affected by graft-versus host reaction. PMID- 4149315 TI - Mechanisms of immunosuppression by antilymphocyte antibody. PMID- 4149316 TI - Radiobiology as the basis of radiotherapy. PMID- 4149317 TI - A histochemical study of the avian liver. PMID- 4149318 TI - Kidney preservation in a hypothermic "cytoplasmic" solution before transplantation. PMID- 4149319 TI - [Monorchism]. PMID- 4149320 TI - [Correction of the liver circulation disorders in ether and fluothane anesthesia]. PMID- 4149321 TI - Initial clinical experience with I.C.I. 66.082, a new beta-adrenergic blocking agent, in hypertension. PMID- 4149322 TI - The William B. Sherman Memorial Address in memory of Dr. W. B. Sherman. PMID- 4149323 TI - Attempted induction of interferon by bacterial vaccines in allergic and nonallergic humans. PMID- 4149324 TI - Theophylline and chlorpheniramine in childhood asthma. Dose requirements for children 6 to 12 years (therapeutic orphans) and young adults 13 to 18 years of age receiving cromolyn sodium prophylaxis. PMID- 4149325 TI - Controlled interviews using drugs. II. Comparisons between restricted and freer conditions. PMID- 4149326 TI - Postrelease adjustment of day and full-time psychiatric patients. PMID- 4149327 TI - A psychosocial description of penitentiary inmates. PMID- 4149328 TI - Pathogenesis of autoimmunity in New Zealand mice. V. Loss of thymic suppressor function. PMID- 4149329 TI - Nonphagocytic release of neutral protease and beta-glucuronidase from human neutrophils. Regulation by autonomic neurohormones and cyclic nucleotides. PMID- 4149330 TI - Presence of the complete sorbitol pathway in the human normal umbilical cord tissue. PMID- 4149331 TI - Effects of alprenolol on central hemodynamics and exercise tolerance in patients with angina pectoris. PMID- 4149333 TI - Striato-pallidonigral degeneration. (A diagnostic dilemma--case report). PMID- 4149332 TI - Effect of carbohydrates upon fluorescence of reduced pyridine nucleotides from perifused isolated pancreatic islets. PMID- 4149334 TI - [Serum enzymogram in experimental transplantation of the small intestine]. PMID- 4149335 TI - [Evaluation of the use of vascular agents in massive acute hemorrhage]. PMID- 4149336 TI - [Ultrastructure of cerebral neurons during intravenous and inhalation anesthesia]. PMID- 4149337 TI - Plasmodium berghei: mechanisms and sites of resistance to sporogonic development in different mosquitoes. PMID- 4149339 TI - Physicians' assistants update--fall 1973. PMID- 4149338 TI - Circadian rhythms during drug-induced coma. (Transverse study of rectal temperature, heart rate, systolic blood pressure, urinary water and potassium). PMID- 4149340 TI - Spontaneous epizootic of pneumococcus infection in guinea-pigs. PMID- 4149341 TI - Letter: Cavitary pneumonia in a 76-year-old woman. PMID- 4149342 TI - [Increase of sulfobromophthalein clearance by phenothiazines]. PMID- 4149343 TI - A calcium ionophore simulating the action of epinephrine on the alpha-adrenergic receptor. AB - Calcium acting through the ionophore A-23187 caused massive K(+) release from rat parotid slices. The ionophore thus simulates the action of epinephrine on the alpha-adrenergic receptor in this system. The alpha-adrenergic and cholinergic receptors are, however, not involved in the action of the ionophore since phetolamine and atropine had no effect on the ionophore-induced K(+) release. Amylase secretion, which is induced by epinephrine through the beta-adrenergic receptor but does not require Ca(++) in the medium, was only slightly increased by the ionophore in the presence of Ca(++). The K(+) released by Ca(++) through the ionophore was regained by the cells upon chelation of Ca(++) with ethylene glycol bis(beta-aminoethyl ether)-N,N'-tetraacetic acid. Similar to the action of epinephrine on the alpha-adrenergic receptor, the K(+) release induced by the ionophore is specific for Ca(++), which cannot be substituted by 2.5 mM Sr(++), Mg(++), or Ba(++). The results suggest that epinephrine, like the ionophore, introduces Ca(++) into the cell to mediate K(+) release. It is proposed that the ionophore A-23187 may be an effective probe to test whether other Ca(++) requiring hormones and neurotransmitters act in a similar fashion to produce their diverse physiological responses. PMID- 4149344 TI - Activation of transcription of hut DNA by glutamine synthetase. AB - The correct transcription of the hut (histidine utilization) operon DNA of Salmonella typhimurium requires activation either by 3':5'-cyclic adenosine monophosphate and catabolite-activating protein or by nonadenylylated glutamine synthetase (EC 6.3.1.2.). Thus, glutamine synthetase plays a regulatory role distinct from its enzymatic function. PMID- 4149345 TI - Blood pressure elevation in pregnancy. PMID- 4149346 TI - [General complications following fractures of the lower extremities]. PMID- 4149347 TI - New health professionals in pediatrics. PMID- 4149348 TI - Identification and partial characterization of inositol: NAD+ epimerase and inosose: NAD(P)H reductase from the fat body of the American cockroach, Periplaneta americana L. PMID- 4149349 TI - On the effect of temperature on the absorption spectra of free and protein-bound flavines. PMID- 4149350 TI - Isolation and characterization of a phosphonic acid rich glycoprotein preparation from Metridium dianthus. PMID- 4149351 TI - [Suppression of primary and secondary immune response by antilymphocyte serum, shown by antigen-specific proliferation activity in graft-vs-host model]. PMID- 4149352 TI - Differences in distribution pattern of marker enzymes among subcellular fractions from Morris hepatoma 16. PMID- 4149353 TI - Hypertensive pulmonary vascular disease complicating congenital heart disease. A review. PMID- 4149354 TI - The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K 12. Intra and intersubunit interactions between the catalytic regions of the bifunctional enzyme. PMID- 4149356 TI - Letter: Salicylazosulfapyridine in clinical practice. PMID- 4149355 TI - Effects of phenobarbital administration on rates of ethanol clearance and on ethanol-oxidizing enzymes in man. PMID- 4149358 TI - Mapping of the pneumococcus chromosome. Linkage between the genes conferring resistances to erythromycin and tetracycline and its implication to the replication of the chromosome. PMID- 4149357 TI - Segmental response of the macrophage plasma membrane to a phagocytic stimulus. AB - A method of attaching mouse RBCs to mouse macrophages is described. Both cell types were coated with rabbit anti-mouse macrophage F(ab')(2), and cross-linkage of cells was effected with sheep F(ab')(2) directed against rabbit F(ab')(2). 98% of macrophages attached an average of 11 RBCs each. Attachment occurred at 37 degrees C and was stable for at least 4 h. Less than 0.1% of macrophages ingested RBCs under these conditions. Latex particles and opsonized pneumococci were ingested as avidly by RBC-coated macrophages as by native macrophages. Ingestion of these particles did not prompt ingestion of attached RBCs. When anti-RBC IgG was added, however, over 90% of macrophages ingested an average of six RBCs each. Thus, ingestion of one particle does not trigger generalized phagocytosis of all particles attached to the cell's plasma membrane, and the phagocytic stimulus is confined to the segment of the cell's plasma membrane immediately adjacent to the particle being ingested. PMID- 4149360 TI - [Introductiory composition of a purpose description for health-education in Denmark]. PMID- 4149359 TI - Intrarenal effects of phenoxybenzamine on sodium reabsorption. PMID- 4149361 TI - [Antibiotics for recurrent acute otitis media in infants under two (author's transl)]. PMID- 4149362 TI - Discrimination between mathematical models of biological systems exemplified by enzyme steady state kinetics. PMID- 4149364 TI - Recovery from intravenous sedation, secobarbital and propiomazine. PMID- 4149363 TI - Enzyme histochemistry of the liver in extrahepatic biliary obstruction. A comparison between man, dog and rat. PMID- 4149365 TI - Cardiovascular effects of tolamolol (UK-6558), a new beta-adrenoreceptor blocking drug, in pinealectomized hypertensive rats. PMID- 4149366 TI - Effect of chronic ethanol treatment on tryptophan oxygenase, tyrosine aminotransferase and general protein metabolism in the intact and perfused rat liver. PMID- 4149367 TI - Aggregation of blood platelets by biogenic amines and its inhibition by antiadrenergic and antiserotoninergic agents. PMID- 4149368 TI - Effect of 16alpha-cyanopregnenolone on the hydroxylation of lithocholic acid by rat liver microsomes. PMID- 4149369 TI - Triphosphopyridine nucleotide specific isocitrate dehydrogenase from Azotobacter vinelandii. Alkylation of a specific methionine residue and amino acid sequence of the peptide containing this residue. PMID- 4149370 TI - Regulation of corticosteroid hydroxylations: the intramitochondrial dielectric constant and proteolipids of adrenodoxin and cytochrome P450. PMID- 4149371 TI - Dental epidemiological surveys of Sarawak school children. PMID- 4149372 TI - A periodontal programme for a developing country (Western Samoa). PMID- 4149374 TI - The role of oxygenated cytochrome P-450 and of cytochrome b5 in hepatic microsomal drug oxidations. PMID- 4149373 TI - Newer aspects of substrate binding to cytochrome P-450. PMID- 4149375 TI - DPNH synergism of TPNH-dependent mixed function oxidase reactions. PMID- 4149376 TI - Pseudomonas putida cytochrome P-450: ligands of the substrate-free and substrate bound states of the ferric hemoprotein. PMID- 4149378 TI - Effects of inhibitors on drug metabolism. PMID- 4149377 TI - Role of phospholipid in the reconstituted liver microsomal mixed function oxidase system containing cytochrome P-450 and NADPH-cytochrome P-450 reductase. PMID- 4149380 TI - Formation and binding of carbanions by cytochrome P-450 of liver microsomes. PMID- 4149379 TI - Mechanisms of inhibition of drug metabolic reactions. PMID- 4149381 TI - Metyrapone and other modifiers of microsomal drug metabolism. PMID- 4149382 TI - Enhancement of type II substrate oxidation and of azo reduction in the isolated rat liver and in vitro by metyrapone. PMID- 4149384 TI - Structural aspects of the active site of cytochrome P-450cam. PMID- 4149383 TI - Determination of active centers of hepatic microsomal cytochrome P-450 by metyrapone, applying mutual depletion system kinetics. PMID- 4149385 TI - Effect of steroids on drug metabolism in male and female rats. PMID- 4149386 TI - Chemistry of cytochrome P-450 purified from endocrine systems. PMID- 4149387 TI - Induction of the unspecific microsomal hydroxylase in the human liver. PMID- 4149388 TI - Genetic differences in cytochrome P-450 during induction of mono-oxygenase activities. PMID- 4149390 TI - The effect of phenobarbital on the turnover of messenger RNA's for microsomal enzymes. PMID- 4149389 TI - Initiation factor activity in liver after 3-methylcholanthrene administration. PMID- 4149391 TI - Synthesis and degradation of microsomal hemoproteins. PMID- 4149392 TI - The regulation of heme synthesis related to drug metabolism. PMID- 4149393 TI - Drug-induced destruction of cytochrome P-450. PMID- 4149394 TI - Breakdown of cytochrome P-450 heme by secobarbital and other allyl-containing barbiturates. PMID- 4149395 TI - Heme and hemoprotein catabolism during stimulation of microsomal lipid peroxidation. PMID- 4149396 TI - The possible implication of heme transfer from cytochrome P-420 to albumin in the metabolism of cytochrome P-450. PMID- 4149397 TI - The role of cytochrome P-450 in the N-oxidation of individual amines. PMID- 4149398 TI - Characterization of partially purified cytochromes P-450 and P-448 from rat liver microsomes. PMID- 4149399 TI - Microsomal flavoprotein-catalyzed N-oxidation of arylamines. PMID- 4149400 TI - Oxidation of an amino carbinol by an NAD+-dependent microsomal dehydrogenase. PMID- 4149401 TI - Phenylacetone oxime--an intermediate in amphetamine deamination. PMID- 4149402 TI - The mechanism of microsomal deamination: heavy isotope studies. PMID- 4149403 TI - The influence of some hepatic enzyme inducers and inhibitors on extrahepatic drug metabolism. PMID- 4149404 TI - The cytochrome P-450-containing mono-oxygenase system of rat kidney cortex microsomes. PMID- 4149405 TI - Characterization of lung microsomes as related to drug metabolism. PMID- 4149406 TI - The role of cytochrome P-450 of placenta in facilitated oxygen diffusion. PMID- 4149407 TI - A specific carrier for oxygen and carbon monoxide in the lung and placenta. PMID- 4149408 TI - Some selected studies on hepatic microsomal drug-metabolizing enzymes- environment interactions. PMID- 4149410 TI - Effect of synergists on drug metabolism. PMID- 4149409 TI - Induction of aryl hydrocarbon hydroxylase in human skin. PMID- 4149411 TI - Differences in P-420 hemoproteins from untreated and 3-methylcholanthrene-treated rats. PMID- 4149413 TI - Drug metabolism as a cause of drug toxicity. PMID- 4149412 TI - Interindividual differences in rates of drug oxidation in man. PMID- 4149414 TI - Effects of phenobarbital treatment on biliary excretion in man. PMID- 4149415 TI - The significance and characterization of hepatic microsomal ethanol oxidation in the liver. PMID- 4149416 TI - The role of hydrogen peroxide and catalase in hepatic microsomal ethanol oxidation. PMID- 4149417 TI - Ethanol metabolism: oxidative and peroxidative mechanisms. PMID- 4149419 TI - Tetrahydrocannabinol metabolism in man. PMID- 4149418 TI - Optical and magnetic probes of the structure of cytochrome P-450's. PMID- 4149420 TI - Interindividual differences in drug oxidation: clinical importance. PMID- 4149421 TI - Cytochrome P-450 associated with free hepatic polyribosomes. PMID- 4149422 TI - Dynamic organization of endoplasmic reticulum membranes. PMID- 4149423 TI - Partial purification and some spectral properties of hepatic microsomal cytochrome P-450. PMID- 4149424 TI - Kinetics and inelastic light-scattering studies of the role of phospholipids in the microsomal membrane structure. PMID- 4149425 TI - Turnover of enzyme proteins in microsomal membrane. PMID- 4149426 TI - The synthesis and degradation of membrane proteins. PMID- 4149427 TI - On the mechanism of hydroxylation reactions catalyzed by cytochrome P-450. PMID- 4149428 TI - Studies on the molecular function of cytochrome P-450 during drug metabolism. PMID- 4149429 TI - Studies on the metabolic effect induced in the rat by a high-fat diet. Estimation of glucose-carbon utilization through various metabolic pathways in epididymal adipose tissue. PMID- 4149430 TI - Interaction of mixed-function oxidation with biosynthetic processes. 1. Inhibition of gluconeogenesis by aminopyrine in perfused rat liver. PMID- 4149431 TI - Inhibition of enzymes which interact with citrate by (--)hydroxycitrate and 1,2,3,-tricarboxybenzene. PMID- 4149432 TI - [Caries prevention at Deszk by fluoridation of table salt. 8. Incidence of caries during a 5-year trial period]. PMID- 4149434 TI - Periodontal disease condition and oral hygiene status of public school children, city of Manila. PMID- 4149433 TI - Characterization of solubilized cytochrome P-450. PMID- 4149435 TI - Suppression of DNA synthesis in hepatoma cells exposed to glucocorticoid hormone in vitro. AB - Glucocorticoid hormone is shown to markedly suppress DNA synthesis in a line of rat hepatoma cells in vitro. In the presence of 300 nM hydrocortisone or 30 nM dexamethasone the incorporation of radioactive thymidine falls to 50% of control levels by 36 hr, and at higher concentrations of hormone inhibition can be noted as early as 12 hr and is nearly complete by 24 hr. This inhibition of radioactive thymidine incorporation reflects a true suppression of DNA synthesis, is accompanied by a corresponding inhibition of cell proliferation, and is readily reversible upon subsequent removal of hormone. In contrast to previously described effects of the glucocorticoid hormones on various cells of lymphoid origin, the inhibition of DNA synthesis in these hepatoma cells is not accompanied by appreciable cell lysis or by degradation of preformed DNA, and even when [(3)H]thymidine incorporation into DNA is inhibited by 90% or more, incorporation of [(14)C]uridine into RNA proceeds with little change. These findings all parallel previous observations on the effects of glucocorticoid hormone on the livers of intact animals and suggest that studies on the mechanism of the inhibition of DNA synthesis in the present more isolated system may lead to a better understanding of the means by which these compounds inhibit liver growth in vivo. Despite the ready suppressibility of DNA synthesis in these hepatoma cells and in two other cell lines of liver origin, none of these cell lines was found to be inducible for tyrosine aminotransferase. The apparent dissociation between two "steroid-sensitive" phenomena is of interest and warrants further investigation. PMID- 4149436 TI - [Bone marrow transplantation in aplastic anemias and acute leukemias. Views and prospects]. PMID- 4149437 TI - [Oxidative-reductive enzymes and the phenomenon of anaplasia in neuroectodermal tumors (a histochemical study)]. PMID- 4149438 TI - [Blood urokaninase and histidase activity in pregnancy complicated by toxicosis]. PMID- 4149439 TI - Histochemical fiber composition of some facial muscles in the cat in relation to their contraction properties. PMID- 4149440 TI - Excerpts from the casebook of Jason Harbro, M.D., AME. PMID- 4149441 TI - Metabolic stability of 2, 3, 7, 8-tetrachlorodibenzo-P-dioxin in mammalian liver microsomal systems and in living mice. PMID- 4149442 TI - [Comparison of the beta-cytotropic effect of glymidine sodium (glycodiazine), glucagon, and isopropylnoradrenaline in rats]. PMID- 4149443 TI - Biosynthesis and degradation of saccharopine, an intermediate of lysine metabolism. AB - Lysine-2-oxoglutarate reductase was prepared from ox liver and its characteristics were examined. Its activity was totally inhibited in the presence of NH(4)Cl. Under conditions that inhibit saccharopine formation, and in the presence of NADP(+), ox liver mitochondria were found to catalyse the hydrolysis of saccharopine to lysine and alpha-oxoglutarate. The enzyme involved was named saccharopine oxidoreductase. It was partially purified and separated from lysine oxoglutarate reductase. Comparison of the properties of these two enzymes showed that saccharopine degradation was stimulated under conditions that inhibit its formation. The effect of pH, various cofactors and stability during incubation confirm that saccharopine biosynthesis from, and degradation to, lysine are catalysed by two distinct enzymes. PMID- 4149444 TI - The effect of magnesium ions on the dimethylaniline oxidation rate and electron transfer in liver microsomal fraction. AB - 1. Reactions of N-demethylation, p-hydroxylation and N-oxidation of one substrate, i.e. dimethylaniline, have been used to show that the activating effect of Mg(2+) takes place only in the first two reactions. 2. An increase in V(max.) of N-demethylation of dimethylaniline is accompanied by an increase in K(m). In the p-hydroxylation of dimethylaniline V(max.) increases whereas K(m) does not change. A comparison of the changes in the K(m) values of these reactions with the change in K(s) shows that in both cases K(m) does not characterize the affinity of cytochrome P-450 for dimethylaniline. 3. The rate limiting site of N-demethylation and p-hydroxylation of dimethylaniline, as well as the total rate of NADPH oxidation in the presence of dimethylaniline, is between cytochromes b(5) and P-450. Addition of Mg(2+) to the incubation medium changes the hydrophobic environment of phosphatidylcholine in the membrane, the process being accompanied by a sharp increase in the fluorescence quantum yield of 8-anilinonaphthalene-1-sulphonate. PMID- 4149446 TI - [Changes in the level of adenylic nucleotides and oxidation enzymes in the myocardium during the action of drugs on the adrenoreceptors]. PMID- 4149447 TI - [Effect of ions and biologically active substances on the ability of blood to bind acetylcholine in vitro]. PMID- 4149445 TI - The tritium isotope effect of sn-glycerol 3-phosphate oxidase and the effects of clofenapate and N-(2-benzoyloxyethyl)norfenfluramine on the esterification of glycerol phosphate and dihydroxyacetone phosphate by rat liver mitochondria. AB - 1. Owing to a (3)H isotope effect, the mitochondrial sn-glycerol 3-phosphate oxidase (EC 1.1.99.5) had a mean activity which was 8.4 times less with sn-[2 (3)H]-rather than with sn-[1-(14)C]glycerol 3-phosphate as a substrate. 2. A method for measuring the simultaneous synthesis of lipid from glycerol phosphate and dihydroxyacetone phosphate in rat liver mitochondria is described. 3. The lipid synthesized by rat liver mitochondria from sn-[1-(14)C]glycerol 3-phosphate was mainly phosphatidate and lysophosphatidate, whereas that synthesized from dihydroxy[1-(14)C]acetone phosphate was mainly acyldihydroxyacetone phosphate. 4. Additions of NADPH facilitated the conversion of acyldihydroxyacetone phosphate into lysophosphatidate and phosphatidate. 5. Hydrazine (1.4mm) or KCN (1.4mm) inhibited the synthesis of lipids from dihydroxyacetone phosphate but not from glycerol phosphate. 6. Clofenapate (1-2.5mm) inhibited the synthesis of lipids from dihydroxyacetone phosphate but slightly stimulated synthesis from glycerol phosphate. 7. The methanesulphonate of N-(2-benzoyloxyethyl)norfenfluramine, at 0.25-0.75mm, inhibited lipid synthesis from both glycerol phosphate and dihydroxyacetone phosphate. PMID- 4149448 TI - [Effect of ganglionic block on liver circulation]. PMID- 4149449 TI - Biotransformation of 2-hydroxynicotinic acid: N-riboside formation in vivo. PMID- 4149450 TI - N-methylation, a newly identified pathway in the dog for the metabolism of oxprenolol, a beta-receptor blocking agent. PMID- 4149451 TI - Metabolism of 2-ethyl-2-methylsuccinimide (ethosuximide) in the rat and human. PMID- 4149452 TI - Metabolism of tetralin and toxicity of Cuprex in man. PMID- 4149453 TI - Dialkyl esters of methotrexate and 3',5'-dichloromethotrexate: synthesis and interaction with aldehyde oxidase and dihydrofolate reductase. PMID- 4149454 TI - Excretion of 3H-digitoxin and its metabolites following spironolactone pretreatment in rats. PMID- 4149455 TI - The distribution of chlorcyclizine-14C in pregnant mice. PMID- 4149456 TI - n-Octylamine difference spectra of cytochromes P-450 and P-448 from rat and mouse liver: a species difference. PMID- 4149457 TI - Membrane-bound gamma-glutamyl transpeptidase and its role in phenylalanine absorption-reabsorption in the larva of Musca domestica. PMID- 4149458 TI - Effect of adrenergic blockade on the duodenal motor reaction induced by some ions. PMID- 4149459 TI - Structure-activity relationship studies on inhibition of histamine uptake by rabbit blood platelets. PMID- 4149461 TI - Indirect alpha adrenergic response to isoproterenol in the dog spleen. PMID- 4149460 TI - Androgen assimilation by the epithelium and muscle of the guinea-pig seminal vesicle. PMID- 4149462 TI - Selective beta adrenergic receptor antagonism in the anesthetized dog. PMID- 4149463 TI - The relationships between alpha receptor block, inhibition of norepinephrine uptake and the release and metabolism of 3H-norepinephrine. PMID- 4149464 TI - Trans-synaptic induction of choline acetyltransferase in the preganglionic neuron of the peripheral sympathetic nervous system. PMID- 4149465 TI - Editorial: A lesson from Gus. PMID- 4149466 TI - The genetic control of molybdoflavoproteins in Aspergillus nidulans. II. Use of NADH dehydrogenase activity associated with xanthine dehydrogenase to investigate substrate and product inductions. PMID- 4149467 TI - Melanin: a unique biopolymer. PMID- 4149468 TI - Experimental lobar pneumonia in canine lung grafts. PMID- 4149469 TI - Effect of lymphoid tissue transplants on the intensity of an existing graft versus-host reaction. PMID- 4149470 TI - Inhibition of graft-versus-host reactions in mice by host-directed antibody. Effect of serum dose and immunoglobulin subclass. PMID- 4149471 TI - [Eye injuries by stinging jellyfish]. PMID- 4149472 TI - Competitive antagonism between phenoxybenzamine and acetylcholine in isolated rat atria. PMID- 4149473 TI - Contractile responses to phenylephrine and carbachol in circular rabbit fundus strips at varying external K+ AND Ca++ concentrations. PMID- 4149474 TI - The uses and relative hazard potential of psychoactive drugs. PMID- 4149475 TI - Further studies of the capsular polysaccharide of Pneumococcus Type II. PMID- 4149476 TI - [Use of electrophoresis for studying pachycarpine hydroiodide]. PMID- 4149477 TI - Probable 16 year course in a patient with thrombotic thrombocytopenic purpura. PMID- 4149478 TI - Failure of corticosteroid in the treatment of Duchenne (pseudo-hypertrophic) muscular dystrophy. Report of a clinically matched three year double-blind study. PMID- 4149480 TI - Curling. The psychological value of the sport. PMID- 4149479 TI - A perspective of peripheral health care. PMID- 4149481 TI - Aneurysm of the gastroduodenal artery: a cause of gastrointestinal bleeding. PMID- 4149482 TI - Brown Recluse spider bite. Increasing incidents in Northern Illinois. PMID- 4149483 TI - Common problems in high risk nurseries. PMID- 4149484 TI - The viewbox. Dermatomyositis. PMID- 4149485 TI - Cardiovascular collapse during gynecological laparoscopy. PMID- 4149486 TI - Marcus P. Hatfield--the first pediatrician at Northwestern. PMID- 4149487 TI - EKG of the month. Sinus rhythm and premature ventricular beats. PMID- 4149488 TI - Surgical grand rounds: Tuberculosis of kidney. PMID- 4149489 TI - [Hypotension and the orthostatic syndrome. Disease evaluation and therapy from the viewpoint of professional practice]. PMID- 4149490 TI - [Drug and physical therapy of hypotension]. PMID- 4149491 TI - Ulcerative colitis in Bombay. PMID- 4149492 TI - Australia antigen and liver disease: a review article. PMID- 4149493 TI - [Ophthalmologic changes in periarteritis nodosa]. PMID- 4149494 TI - Problems and prospects for physician assistants in Ohio. Experience with the education of physician assistants in anesthesia in Cleveland. PMID- 4149495 TI - Inhibition of hypertensive reflexes by propranolol. PMID- 4149496 TI - Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH. PMID- 4149497 TI - Determination of diphenhydramine in plasma by gas chromatography. PMID- 4149498 TI - [Voluntary and accidental poisoning. Apropos of 757 cases]. PMID- 4149499 TI - Experimental cryptorchism: effect on serum LH and FSH in the rat. PMID- 4149500 TI - [The lungs in the field of collagen diseases (author's transl)]. PMID- 4149501 TI - Induction of heterotopic bone formation by demineralized dentin in guinea pigs: relationship to time. PMID- 4149502 TI - High-dose urography in advanced renal failure. I. Evaluation of diagnostic value. PMID- 4149503 TI - [Binding of a human serum glycoprotein on isolated guinea pig ileum producing a decrease in histamine biological activity]. PMID- 4149504 TI - Oral contraceptives and psychiatric disturbance: evidence from research. PMID- 4149505 TI - Hyperactive production of antibody of a boy with thymic dysplasia undergoing graft versus host reaction. PMID- 4149506 TI - Immunoglobulin classes and IgG subclasses of human antinuclear antibodies. A correlation of complement fixation and the nephritis of systemic lupus erythematosus. PMID- 4149507 TI - [Release of cholinergic substances in the caudal mesenteric ganglion during peripheral reflexes]. PMID- 4149508 TI - [Somatotropin release after alpha-adrenergic stimulation in man]. PMID- 4149509 TI - [International Nurse's Day; 12 May, 1972]. PMID- 4149510 TI - [General meeting of the members of the Hellenic National Nurses' Association. March 20, 1972]. PMID- 4149511 TI - [International nursing aspects]. PMID- 4149512 TI - Screening for galactosemia. Studies of the gene frequencies for galactosemia and the Duarte variant. PMID- 4149513 TI - Effect of oxidized glutathione on protein synthesis. PMID- 4149514 TI - Mutants of Klebsiella aerogenes lacking glutamate dehydrogenase. AB - A mutant of Klebsiella aerogenes lacking glutamate synthase activity (asm-200) is blocked in only one pathway of glutamate synthesis and can still use glutamate dehydrogenase to produce glutamate when ammonia in sufficient concentration, i.e., higher than 1 mM, is provided in the medium. However, a mutant that has neither glutamate synthase nor glutamate dehydrogenase activities (asm-200, gdhD1) requires glutamate. Transductants obtained by phage grown on wild-type cells of this double mutant, selected on medium containing less than 1 mM ammonia, regain glutamate synthase but not glutamate dehydrogenase. Surprisingly, these gdhD1 transductants grow as well in a variety of media as does a strain with glutamate dehydrogenase activity. Furthermore, transductions with these and other mutants indicate that the genes encoding glutamate synthase, glutamate dehydrogenase, glutamine synthetase, and citrate synthase are not closely linked. PMID- 4149515 TI - Specificity of the autolysin of Streptococcus (Diplococcus) pneumoniae. AB - A Streptococcus (Diplococcus) pneumoniae autolysin, partially purified from cellular autolysates, was optimally active at pH 7.0 and was stimulated by monovalent cations. Addition of autolysin to walls resulted in the appearance of only N-terminal l-alanine, whereas no glycosidase activity was observed. Walls which had been solubilized by autolysin were separated by gel filtration into a low-molecular-weight peptide containing amino acids in the same ratios found in intact walls and a high molecular fraction containing the amino acid-deficient peptidoglycan backbone. Thus, the major activity is an N-acetylmuramyl-l-alanine amidase. In addition, walls undergoing spontaneous lysis revealed no glycosidase activity but showed an increase in only N-terminal alanine. Autolysin, which was bound to walls in saline, was almost completely removed when walls were washed in distilled water, and all of the activity was recovered in the water wash fluid. PMID- 4149516 TI - Early effects of monoamine oxidase inhibitors on dopamine metabolism and monoamine oxidase activity in the neostriatum of the rat. PMID- 4149517 TI - [Decrease of venous inflow as a basic hemodynamic mechanism of the action of hypotensive agents]. PMID- 4149518 TI - [State of tonus of the pulmonary circulation vessels under the influence of certain cardiac glycosides and analeptics]. PMID- 4149520 TI - [Effect of pharmacological desympathization on the chemism and functional state of the mitochondria of skeletal muscle cells]. PMID- 4149519 TI - [Cognition disorders in the course of treatment with neuroleptics]. PMID- 4149522 TI - [Problems in the treatment of testicular dystopia]. PMID- 4149523 TI - [Exogenous poisoning (physiopathology, pathobiochemistry and therapy)]. PMID- 4149524 TI - [Psychiatric tasks of medical practice as shown on the example of depressive neurasthenic syndromes in middle age]. PMID- 4149525 TI - [Experience with leptril therapy for preschool children]. PMID- 4149526 TI - Amidopyrine-N-demethylation by lung 9000 x g supernatant of newborn and adult rats. PMID- 4149527 TI - Description and physiological characterization of a coryneform hydrogen bacterium, strain 14 g. PMID- 4149528 TI - New amino acids, and heterocyclic compounds participating in the Stickland reaction of Clostridium sticklandii. PMID- 4149529 TI - [Starting point and technic of a complex study (clinical, social and personality characteristics)]. PMID- 4149530 TI - Laboratory colonization of Toxorhynchites brevipalpis. AB - Toxorhynchites brevipalpis, a predator on larvae of Aedes aegypti and other mosquitos, was successfully colonized in the laboratory. At 25 degrees C, embryonic development was completed within 50 hours of oviposition, while larval and pupal development together took a further 27-41 days. The adult mosquitos mated in cages as small as 15x15x15 cm, and the embryonated eggs were obtained 6 31 days after the adults emerged. PMID- 4149531 TI - Studies on partially purified pig liver steroid delta 4-5 beta-reductase activity. PMID- 4149532 TI - Analgesia during labor: effect on the fetus and neonate. PMID- 4149533 TI - The initiation of labor. PMID- 4149535 TI - Date on the enzyme histochemistry of the ependyma lining the infundibular and inframammillary recesses of the third cerebral ventricle, with special regard to the connexions of the tanycytes. PMID- 4149534 TI - Regulation by the precompetent cell culture of the appearance of spontaneous and induced competence. PMID- 4149536 TI - Procamine and other basic peptides in the venom of the honeybee (Apis mellifera). PMID- 4149537 TI - Effect of acetoacetate on liver and blood pyridine nucleotides in rats. PMID- 4149538 TI - Distribution of tyrosine alpha-ketoglutarate transaminase activity in Kupffer cell and whole liver fractions of rat liver. PMID- 4149539 TI - [Dermal form of periarteritis nodosa in a 13-year-old girl]. PMID- 4149542 TI - The reduction of methemoglobin in the human erythrocyte. PMID- 4149540 TI - [Modern views on the pathogenetic mechanisms of experimental labiopalatal clefts]. PMID- 4149543 TI - Workshop summary on genetic determinants of cell-mediated immune reactions in the mouse. PMID- 4149541 TI - Alkali metal cations: effects on aggression and adrenal enzymes. PMID- 4149544 TI - Mouse mixed lymphocyte reactions and cell-mediated lympholysis: genetic control and relevance to antigenic strength. PMID- 4149545 TI - Genetic determinants for the graft-vs.-host reaction in the H-2 complex. PMID- 4149546 TI - Spleen cell transplantation in mice: influence of non-H-2 M locus on graft-vs. host and host-vs.-graft reactions. PMID- 4149547 TI - The histocompatibility complex of rhesus monkeys. 3. Evidence for a major MLR locus and histocompatibility-linked Ir genes. PMID- 4149548 TI - The Ag-B locus rats: a major histocompatibility complex? PMID- 4149549 TI - Activation of T cells by H-2 factors in the graft-vs-host reaction. PMID- 4149550 TI - Serologic detection of antigens controlled by the Ir region of the H-2 complex in the mouse. PMID- 4149551 TI - [A controlled clinical trial of a new bladder spasmolytic drug--Urispadol]. PMID- 4149552 TI - [Editorial: Hyperactivity of the bladder]. PMID- 4149553 TI - Separation of alkaline phosphatase isoenzymes and evaluation of the clinical usefulness of this determination. PMID- 4149554 TI - Recurrent membranoproliferative glomerulonephritis with glomerular properdin deposition in allografts. PMID- 4149556 TI - Collection of lymph from dog jejunal allotransplant. I. Cell transformation and lymphocytotoxicity against the host. PMID- 4149555 TI - Histochemical studies of hepatic enzymes in dogs subjected to barbiturate anaesthesia. PMID- 4149557 TI - Relationships of the catalytic properties of human plasma and platelet transglutaminases (activated blood coagulation factor XIII) to their subunit structures. PMID- 4149558 TI - MMPI low-point codes for a "normal" young adult population: a normative study. PMID- 4149559 TI - Separate versus full MMPI method: reliability of the pseudoneurologic scale. PMID- 4149560 TI - Abbreviated MF and SI scales: efficacy with parents of emotionally disturbed children. PMID- 4149561 TI - Regulation of the antibody response to type 3 pneumococcal polysaccharide. 3. Role of regulatory T cells in the development of an IgG and IgA antibody response. PMID- 4149562 TI - The effect of age on the response of rat lymphocytes in mixed leukocyte culture, to PHA, and in the graft-vs-host reaction. PMID- 4149563 TI - Effects of various feeding and exercise regimens on rat growth and survival. PMID- 4149564 TI - Use of surface-decalcified allogeneic bone and autogenous marrow in extensive mandibular defects. PMID- 4149565 TI - Effect of synthetic luteinizing hormone-releasing hormone on the release of gonadotropins in hypophysogonadal disorders of children and adolescents. IV. Undescended testes. PMID- 4149566 TI - Experimental kerosene pneumonia: evaluation of some therapeutic regimens. PMID- 4149567 TI - [Myocardial infarct in a patient with Wegener's granulomatosis]. PMID- 4149568 TI - [State of the efferent link of baroreceptor reflexes in experimental renal hypertension]. PMID- 4149569 TI - [Pathology of the heart in periarteritis nodosa]. PMID- 4149570 TI - [Activation of the anticoagulating system of blood with adrenaline in rats desympathized by use of 6-hydroxydopamine]. PMID- 4149571 TI - Biochemical basis for nutritional management of preterm infants. PMID- 4149572 TI - Hypoplastic pelvis in association with multiple anomalies. PMID- 4149573 TI - Analysis of photosynthesis in green algae through mutation studies. PMID- 4149574 TI - Central action of 11-(3-dimethylaminopropylidene)-6,11-dihydro-dibenzo (b,e)oxepine hydrocholoride (doxepine). PMID- 4149575 TI - Protection against isoprenaline induced myocardial necroses by beta-adrenergic blocking agents. PMID- 4149576 TI - Beta-adrenergic receptor blockade as a protection against the death of hypoxia. PMID- 4149577 TI - The effects of long term administration of psychotropic drugs on human sleep. I. Methodology and the effects of placebo. PMID- 4149578 TI - Circumvention of early graft-versus-host disease in hemiallogeneic bone marrow transplantation in a case of severe combined immunodeficiency. PMID- 4149579 TI - Parabiosis in immunobiology. PMID- 4149580 TI - Developmental defects of T and B cell lines in humans. PMID- 4149581 TI - [Experience with the use of midantan for treatment and prevention of the neuroleptic syndrome]. PMID- 4149582 TI - [Cardiovascular activity of alpha methyldopa metabolites in the dog]. PMID- 4149583 TI - The depressant action of SKF 525A on the guinea-pig ileum. PMID- 4149584 TI - Primary pneumococcal peritonitis. AB - A case of primary pneumococcal peritonitis in a girl of 9 is presented. The diagnosis was made at laparotomy and confirmed by immediate bacteriological examination. The condition is extremely rare and accounts for 1 in 5 of all cases of primary peritonitis in children. PMID- 4149585 TI - Use of subjective responses to evaluate efficacy of mild analgesic-sedative combinations. PMID- 4149586 TI - Evaluation of hypnotics in outpatients with insomnia using a questionnaire and a self-rating technique. PMID- 4149587 TI - [Dehydrobenzperidol and its effect on the contractility of the nonpregnant human uterus. Preliminary report]. PMID- 4149588 TI - Solitary unicameral bone cyst of the calcaneus. A review of twenty cases. PMID- 4149589 TI - Thymus dependence of lymphocyte trapping. PMID- 4149590 TI - Regulation of the antibody response to type 3 pneumococcal polysaccharide. II. Mode of action of thymic-derived suppressor cells. PMID- 4149591 TI - Glomerulonephritis in the graft-vs-host reaction: serologic demonstration of anti host antibodies. PMID- 4149593 TI - Editorial: Adventure at Anaheim. PMID- 4149592 TI - Decline in suppressor T cell function with age in female NZB mice. PMID- 4149595 TI - [Proceedings: Science and the evaluation system. Contribution to the management of progress]. PMID- 4149594 TI - [Reaction of atrial fibres to stimulation of the intracardiac septal nerves]. PMID- 4149596 TI - [Action of cholinergic analeptics, ganglioplegics and antihistaminics on the product of conception]. PMID- 4149597 TI - Proceedings: Rubidium salts: basic mechanisms of action. PMID- 4149598 TI - [The 25th Congress of Russian Surgeons (50th anniversary of the publication of works of the First post-revolution Congress of Russian Surgeons)]. PMID- 4149599 TI - Inspiratory versus expiratory efforts in pigeons: a search for selective drug influence. PMID- 4149600 TI - A modified screening method for estimating erythrocyte glucose phosphate isomerase. AB - A fluorimetric method to estimate erythrocyte glucose phosphate isomerase is described. Five mul of blood is added to 100 mul of water. Ten mul of the resulting hemolysate is incubated with a reaction mixture (200 mul) containing Tris-HCl buffer pH 8.0, 20 mumoles, MgCl(2) 2 mumoles, nicotinamide adenine dinucleotide phosphate 0.08 mumoles, glucose-6-phosphate dehydrogenase 0.2 EU and fructose-6-phosphate 0.12 mumoles. After ten minutes of 25 degrees C 20 mul of the mixture is added to 2 ml of 0.01 M phosphate buffer pH 7.4 and the nicotinamide adenine dinucleotide phosphate fluorescence determined. Two ml of water was added to the remaining reaction mixture and the hemoglobin concentration determined at 410 nm. The technique is primarily designed for use with small amounts of blood, of widely varying activity, from various animal species. PMID- 4149601 TI - Galactose-I-phosphate uridyl transferase: a new manometric assay specially suited to erythrocyte studies in galactosaemia. PMID- 4149603 TI - Editorial: The challenge. PMID- 4149602 TI - [Plasma insulin levels in endocrine diseases. 4. Effects of adrenergic receptor agents on plasma insulin levels]. PMID- 4149604 TI - Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat. PMID- 4149605 TI - Electrophysiological analysis of the actions of strychnine, bicuculline and picrotoxin on the axonal membrane. PMID- 4149606 TI - Laboratory personnel: the most important aspect of quality control. PMID- 4149607 TI - [Reactivity of lymphocytes of peripheral blood in patients after cornea transplantation]. PMID- 4149608 TI - [Ways of overcoming transplantation immunity in keratoplasty in the humans]. PMID- 4149609 TI - [Plastic surgery of skin with the A. K. Tychinkina's modification in the treatment of persistently unhealing wounds and ulcers of the foot and shin]. PMID- 4149610 TI - Comparative mechanisms of action of antiarrhythmic drugs. PMID- 4149611 TI - [Etiological and epidemiologic evaluation of 474 cases of microbial meningitis observed at Kinshasa (Republic of Zaire)]. PMID- 4149612 TI - Effect of high- and low-protein diets on the regulation of rat liver tyrosine aminotransferase and tryptophan oxygenase activities by L-tyrosine and L tryptophan. AB - Induction of rat liver tyrosine aminotransferase by l-tyrosine and tryptophan oxygenase by l-tryptophan was studied in groups of rats fed on diets containing 18 or 5% protein. The basal activity of hepatic tyrosine aminotransferase of rats receiving 5% protein gradually increased with the age of the animals but that of rats receiving 18% protein did not. l-Tyrosine induced hepatic tyrosine aminotransferase in rats receiving 18% protein when tested at ages from 4 to 20 weeks. When induction by l-tyrosine was carried out in rats receiving the 5% protein diet, significant induction of tyrosine aminotransferase occurred only in 4- or 6-week-old rats. Induction by l-tryptophan of tryptophan oxygenase in liver or the basal activity of this enzyme in liver did not differ between the groups fed on 5 and 18% protein. On changing the diet from 0 to 18% protein, the above mentioned effects on the induction of hepatic tyrosine aminotransferase were reversed. PMID- 4149613 TI - Beta-blockers and plasma renin activity in hypertension. AB - Long-term treatment with propranolol was shown to produce a sustained suppression of the renin-aldosterone system in hypertensive patients, despite concurrent diuretic treatment. However, the antihypertensive effect of this treatment correlated poorly with its effects on plasma renin activity and urinary aldosterone excretion. When prindolol, another beta-adrenergic blocking drug, was substituted for propranolol, blood pressure control was retained, but there was a prompt rise in plasma renin activity, which was not attributable to changes in electrolyte balance. These observations suggest that the antihypertensive action of propranolol and other beta-blockers does not result from their effects on plasma renin activity. PMID- 4149614 TI - Editorial: First aid for poisoning. PMID- 4149616 TI - 3. The use of medical assistants in Rhodesia. PMID- 4149615 TI - Diseases of the skin. Drug therapy of urticaria. AB - Most patients with urticaria can be assessed by taking a relatively simple history with few or no investigations and controlled by a suitable antihistamine given at appropriate times until spontaneous resolution occurs without a complete diagnosis ever being made. Those that do not respond in this way require sometimes quite elaborate investigations, the institution of which would be an imposition in a mild case. Even after full investigation and ringing the changes of all available drugs, too many cases persist to the frustration of all concerned. PMID- 4149617 TI - Subgroups among opiate addicts: a typological investigation. PMID- 4149618 TI - Effect of maleic acid on the ultraviolet absorption of some antihistamine maleate salts. PMID- 4149619 TI - Kinetic studies on the enzymes catalysing the conversion of 17alpha hydroxyprogesterone and dehydroepiandrosterone to androstenedione in the human adrenal gland in vitro. PMID- 4149620 TI - Letter: Colds and antihistaminic effects of vitamin C. PMID- 4149621 TI - Nursing care study: polyarteritis nodosa. PMID- 4149622 TI - [Interaction of hematopoietic stem cells with lymphocytes]. PMID- 4149623 TI - Withdrawal of maintenance drugs with long-term hospitalized mental patients: a critical review. PMID- 4149624 TI - [Angiographical diagnosis of periarteritis nodosa (author's transl)]. PMID- 4149625 TI - [Pulmonary and pleural changes in patients with collagen diseases (author's transl)]. PMID- 4149626 TI - Seventeen year old man with marked eosinophilia and blue toes. PMID- 4149627 TI - [Clinical evaluation of the drug abdoman in peptic ulcer]. PMID- 4149628 TI - Radiosensitivity of lymphocytes. PMID- 4149629 TI - [Clinical pharmacology of a new beta-adrenergic blocking agent--Trasicor]. PMID- 4149630 TI - Effects of diazoxide and beta adrenergic drugs on spontaneous and induced uterine activity in the pregnant baboon. PMID- 4149631 TI - The effects of ritodrine hydrochloride on uterine activity and the cardiovascular system. PMID- 4149632 TI - Double blind cross-over study of the inotropic influence of Tiprenolol (DU21445) and propranolol in patients with ischaemic heart disease. PMID- 4149633 TI - A ceramide tetrasaccharide of human erythrocyte membrane reacting with anti-type XIV pneumococcal polysaccharide antiserum. PMID- 4149634 TI - Effects of phenobarbital, 3-methylcholanthrene, and griseofulvin on the O demethylation of griseofulvin by liver microsomes of rats and mice. PMID- 4149635 TI - Metabolism of 4-(3-(dimethylamino)propyl)-3,4-dihydro-2-(1-hydroxyethyl)-3-phenyl 2H-1,4-benzothiazine (SQ 11,579) under in vitro and in vivo conditions by rats, dogs, and monkey. PMID- 4149636 TI - The relationship between the metabolism of 2,4-dichloro-6-phenylphenoxyethylamine (DPEA) and related compounds and their activities as microsomal mono-oxygenase inhibitors. PMID- 4149637 TI - Changes in rate of ethanol elimination associated with chronic administration of ethanol to chimpanzees and rhesus monkeys. PMID- 4149638 TI - Kinetics of microsomal metabolism and binding of enantiomerically related substrates. PMID- 4149639 TI - Disposition and metabolism of thiopurines. II. Arabinosyl-6-mercaptopurine and ribosyl-6-mercaptopurine. PMID- 4149640 TI - [Drug dependence and addiction from biochemical and pharmaceutical viewpoints]. PMID- 4149641 TI - Conventions and income tax. PMID- 4149642 TI - Utilization of fluorides in areas lacking central water supplies. PMID- 4149643 TI - Graft-vs.-host reactions in reciprocal hybrid mice. I. Dissociation of T-cell activities in the mixed lymphocyte reaction and two graft-vs.-host assays. AB - Spleen cells from BALB/c and C57BL/6 mice were tested for their reactivity against reciprocal hybrid tissues ((BALB/c x C57BL/6) F(1) and (C57BL/6 x BALB/c) F(1)) in three assay systems: the mixed lymphocyte reaction (MLR); the Simonsen spleen-weight graft-vs.-host (GVH) assay; and a GVH mortality assay. It was shown that both F(1)'s serve as equally effective stimulators of parental cells in the MLR. In the spleen-weight assay, BALB/c and C57BL/6 cells were equally active in a given host, but greater splenomegaly was observed in (BALB/c x C57BL/6) F(1) hosts regardless of the donor strain. By contrast, BALB/c cells were much less lethal than C57BL/6 cells in (BALB/c x C57BL/6) F(1) hosts than in (C57BL/6 x BALB/c) F(1) hosts, and to a lesser degree C57BL/6 cells were less lethal than BALB/c cells in (C57BL/6 x BALB/c) F(1) hosts. The possibility that modifying substances may differentially alter reactivity of parental lymphocytes and that considerations other than genotype determine the outcome of a GVH reaction are discussed in detail. PMID- 4149644 TI - Immunological tolerance. Dissociation between in vivo and in vitro reactivity in parabiosed mice. AB - Although most mouse strain combinations succumb to a lethal wasting disease when parabiosed across a strong histocompatibility (H-2) barrier, a high proportion of DBA mice parabiosed to DBA/C3H F(1) hybrids survive and appear healthy. DBA mice accept C3H skin grafts following parabiosis, and may therefore be considered operationally tolerant of C3H antigens. Nonetheless, spleen cells from long-term DBA and F(1) parabionts give normal and enhanced responses, respectively, to C3H antigens in mixed lymphocyte culture (MLC). This indicates that the tolerance mechanism can distinguish between MLC recognition reactivity and in vivo effector reactivity, and that the former can therefore exist in the absence of the latter. PMID- 4149645 TI - The effect of particulate dispersing agents on the antifoaming properties of dimethicone 1000 in antiflatulent products. PMID- 4149646 TI - An infrared study of the interaction between Aerosil-200 and polydimethylsiloxane (dimethicone-1000). PMID- 4149647 TI - The effect of free silica on the mucosal protective and antiflatulent properties of polydimethylsiloxane. PMID- 4149648 TI - The effects of phospholipase C on excitation-contraction coupling mechanisms in smooth muscle. PMID- 4149649 TI - The bronchoconstrictor action of the tetradecapeptide bombesin in the guinea-pig. PMID- 4149650 TI - The effect of carbenicillin on the haemostatic mechanism. PMID- 4149651 TI - Anti-inflammatory activity in human plasma. PMID- 4149653 TI - Stereochemical and structural assignment to benzomorphans by mass spectrometry. PMID- 4149654 TI - The use of radioisotopically labelled methyl esters in the determination of the 15-epimer content of prostaglandins. PMID- 4149652 TI - The binding of conformationally restricted antihistamines to histamine receptors. PMID- 4149655 TI - Letter: Effect of substituted tryptamines on the efflux of noradrenaline from adrenergic nerves in rabbit atria. PMID- 4149656 TI - Letter: The effect of D- and L-p-chlorophenylalanine on the metabolism of 5 hydroxytryptamine in brain. PMID- 4149657 TI - Letter: Reduction of food intake by apomorphine: a pimozide-sensitive effect. PMID- 4149658 TI - Letter: Cerebral phosphodiesterase and the dopamine receptor. PMID- 4149659 TI - Letter: The effect of papaverine on 45Ca2+ uptake in partly depolarized taenia coli of the guinea-pig. PMID- 4149660 TI - Letter: The effect of cannabidiol on maximal electroshock seizures in rats. PMID- 4149661 TI - Letter: Comparison of the relaxant effects of isoprenaline and tolbutamide on uterine and tracheal muscle. PMID- 4149662 TI - Decreased histamine synthesis in the rat brain by hypnotics and anaesthetics. PMID- 4149663 TI - Letter: Application of mass spectrometry to enzyme inhibition studies. PMID- 4149664 TI - Letter: Chemical antagonism by iodine of the pharmacological activity of some sympathomimetic amines. PMID- 4149665 TI - Letter: Effect of chlorimipramine on the rate of tryptophan hydroxylation in the intact and transected spinal cord. PMID- 4149666 TI - Response of the mixed function oxidase system of rat hepatic microsomes to parathion and malathion and their oxygenated analogs. PMID- 4149667 TI - Induction of UDP glucuronyltransferase in the liver and extrahepatic organs of the rat. PMID- 4149668 TI - Studies on a non-pyridine nucleotide dependent, membrane-bound L-(+)-glutamate oxidoreductase in Azotobacter vinelandii. PMID- 4149669 TI - [Recent medical advances and human aspirations inherent to space flights. Elementary concepts of chronobiology]. PMID- 4149670 TI - Effects of the noradrenaline metabolites on tyrosine hydroxylase activity in guinea-pig atria. PMID- 4149672 TI - Investigations of the utilization of NADPH for steroid hydroxylations by adrenal cortex mitochondrial enzymes. PMID- 4149671 TI - An improved method for studying the psychogalvanic reaction in mice and its inhibition by psycholeptic drugs. Comparison with the effects of other pharmacological agents. PMID- 4149673 TI - Observations on the binding site for antimalarial schizontocides. PMID- 4149674 TI - 1. The effect of heparin on the migration of Brugia pahangi microfilariae Culex pipiens. 2. The uptake of B. pahangi microfilariae in C. pipiens and the infectivity of C. pipiens in relation to microfilarial densities. 3. Evidence of a sex-linked recessive gene, sb, controlling susceptibility C. pipiens to B. pahangi. PMID- 4149675 TI - [Treatment of fractures of the anterior portion of the foot]. PMID- 4149676 TI - [Results of action of ultrahigh frequency electromagnetic field (review of the literature)]. PMID- 4149677 TI - [Attempts at rationalizing the maintenance of a serpentarium for industrial purpose]. PMID- 4149678 TI - A review of the scorpions of East Africa with special regard to Kenya and Tanzania. PMID- 4149679 TI - [Destiny of the Orisha Ibeji in Brazil]. PMID- 4149680 TI - Detection of Trypanosoma theileri in Ethiopian cattle ticks. PMID- 4149681 TI - The penetration of the peritrophic membrane of the tsetse flies by trypanosomes. PMID- 4149682 TI - Serological identification of reptile feeds of Glossina. PMID- 4149683 TI - Observations on the activity cycle of Glossina swynnertoni Aust. PMID- 4149684 TI - Ophthalmomyiasis due to Oestrus ovis. PMID- 4149685 TI - [Proof of amoeba in focal organ necrosis in a young Canadian beaver (Castor canadensis)]. PMID- 4149686 TI - Upper-respiratory tract complaint protocol for physician-extenders. PMID- 4149687 TI - [Letter: Cerebral damage caused by enteritis (so-called toxicosis) following oral poliomyelitis vaccination, recognized as vaccination damage]. PMID- 4149688 TI - [Letter: Performing of blood-compatibility tests by medical technical assistants]. PMID- 4149689 TI - Hay fever research: a brief review. A. PMID- 4149690 TI - Surveillance of Venezuelan equine encephalitis in the United States--1972. PMID- 4149691 TI - Preliminary report on the haemodynamic response of hypertensive patients treated with a beta blocker (ICI 66082). PMID- 4149692 TI - Cardiac actions of oxprenolol as studied in dog heart-lung preparations. PMID- 4149693 TI - [Changes in the production of gonadotropic hormones and androgens during the experimental induction of testicular neoplasms]. PMID- 4149694 TI - [Effect of diphacil in vitro on norepinephrine uptake by isolated nerve endings and synaptic vesicles]. PMID- 4149695 TI - [Effect of psychostimulants on membrane permeability for K42 in different areas of the rat brain]. PMID- 4149696 TI - The effects E and A prostaglandins on gastric mucosal blood flow and acid secretion in the rat. AB - 1. The effects of prostaglandins E(1), E(2), A(1) and A(2) on gastric acid secretion and mucosal blood flow were studied by means of a [(14)C]-aniline clearance technique in the anaesthetized rat.2. During intravenous administration of these prostaglandins, in doses which almost completely inhibited pentagastrin- and histamine-induced acid secretion, a fall in clearance was observed.3. Clearance per unit acid secretion increased during prostaglandin administration, precluding a primary reduction in mucosal blood flow as the mechanism of the antisecretory action.4. Prostaglandins increased clearance during basal secretion, indicating a direct vasodilator effect on the gastric mucosa.5. The possibility that endogenous prostaglandins contribute to functional vasodilatation in the gastric mucosa and that exogenous prostaglandins may be of clinical value in the treatment of peptic ulcer is discussed. PMID- 4149698 TI - Editorial: New developments in the treatment of bronchial asthma. PMID- 4149697 TI - Isoprenaline- and exercise- induced tachycardia in the assessment of beta adrenoceptor blocking drugs; a comparison between tolamolol, practolol and propranolol. AB - The effects of tolamolol, propranolol and practolol on both isoprenaline- and exercise-induced tachycardia have been studied in conscious dogs. Tolamolol was approximately equipotent to propranolol and 50 times more potent than practolol in antagonizing exercise-induced tachycardias, but was approximately 12 times less potent than propranolol and 8 times more potent than practolol in blocking isoprenaline-induced tachycardia. It is suggested that antagonism of the tachycardia induced by exercise affords a more meaningful assessment of the possible therapeutic potential of beta-adrenoceptor blocking drugs than does that induced by isoprenaline. PMID- 4149699 TI - Symposium on allergic lung disease. V. Selective drug treatments for bronchial asthma. AB - This paper presents a brief summary of the evidence for selective beta-stimulant and selective glucocorticoid treatments of bronchial asthma. If they are used together correctly, and with sodium cromoglycate in suitable cases, the physician will achieve better control of bronchial asthma in most patients. PMID- 4149700 TI - Adrenergic blocking agents. PMID- 4149701 TI - Phenothiazines and other tranquilizers. PMID- 4149702 TI - Vasopressors and low-flow states. PMID- 4149703 TI - Ion-pair extraction and high-speed liquid chromatography of cephalothin and deacetylcephalothin in human serum and urine. PMID- 4149704 TI - Determination of apparent kinetic constants of the microsomal hydroxylation of amobarbital, hexobarbital, and pentobarbital. PMID- 4149706 TI - The disposition of propranolol. VII. The effects of saturable hepatic tissue uptake on drug clearance by the perfused rat liver. PMID- 4149705 TI - Effects of various centrally active drugs on hepatic microsomal enzymes: a comparative study. PMID- 4149707 TI - The disposition of propranolol. 8. General implications of the effects of liver blood flow on elimination from the perfused rat liver. PMID- 4149708 TI - Species differences in the metabolism of orally administered dopamine-14C and N alanyldopamine-14C. PMID- 4149709 TI - Metabolic disposition of thiamine tetrahydrofurfuryl disulfide in dog and man. PMID- 4149710 TI - Warfarin metabolism in the guinea pig. I. Pharmacological studies. PMID- 4149711 TI - Diphenylhydantoin metabolism. A prospective review. PMID- 4149712 TI - The Medicines Commission's proposed 'prescription only' list. PMID- 4149713 TI - Preparation of a patient with cardiovascular disease for surgery. PMID- 4149714 TI - Myocardial depression during Diplococcus pneumoniae infection in monkeys. PMID- 4149715 TI - Effects of spironolactone on carbon tetrachloride hepatotoxicity. PMID- 4149716 TI - Liver microsomal hydroxylation of steroid hormones after establishing an indigenous microflora in germfree rats. PMID- 4149717 TI - Current trends in the treatment of hypertension. PMID- 4149718 TI - Mechanism of action and pharmacological classification of beta-adrenergic receptor blocking drugs. PMID- 4149719 TI - Beta-adrenergic blockade in ischaemic heart disease. PMID- 4149720 TI - Beta blockade in supraventricular arrhythmias. PMID- 4149721 TI - Beta-adrenergic blocking agents in hypertrophic cardiomyopathy (HOCM). PMID- 4149722 TI - Immunodiffusion studies of pneumococcal antigens with special reference to serotype 27. PMID- 4149723 TI - History of the once close relationship between electrotherapeutics and radiology. PMID- 4149724 TI - A schema for immunotherapy. PMID- 4149726 TI - [Rhythmic behavior of an isolated polyp of a colony of Veretillum cynomorium Pall. (Cnidaria Pennatularia)]. PMID- 4149725 TI - [Catecholeamine biosynthesis in the mollusk Helix pomatia. In vitro demonstration of tyrosine hydroxylase and dopamine-beta-hydroxylase]. PMID- 4149727 TI - Social and psychological characteristics of heroin addicts dropping out of methadone treatment. PMID- 4149728 TI - Some etiological factors in phobic neurosis. PMID- 4149729 TI - Treatment of seasonal allergic rhinitis with 2 percent sodium cromoglycate (BP) solution. PMID- 4149730 TI - Frequency of clinical toxicology test-ordering (primarily overdose cases) and results in a large urban general hospital. PMID- 4149731 TI - Age dependent determinations of lysosomal enzyme activities in the liver and brain as well as the measurements of cytoplasmic enzyme activities in the blood of piracetam pre-treated rats. PMID- 4149732 TI - Effect of riboflavin deficiency on liver microsomal enzyme system and lipid peroxidation in male rats. PMID- 4149733 TI - Stabilization of rat liver tyrosine aminotransferase by drugs. PMID- 4149734 TI - Motorcycle foot. A case report. PMID- 4149735 TI - The athlete's dilemma. PMID- 4149737 TI - Determination of thermodynamics of halogen groups in solutions of drug molecules. PMID- 4149736 TI - Pipradrol in mild depression: a controlled study. PMID- 4149739 TI - The tautomer ratio of histamine. PMID- 4149738 TI - The influence of solution viscosity on the dissolution rate of soluble salts, and the measurement of an "effective" viscosity. PMID- 4149740 TI - Gas-liquid chromatographic estimation in blood of ICI 58 834. PMID- 4149741 TI - Dextromethorphan-monoamine oxidase inhibitor interaction in rabbits. PMID- 4149742 TI - The 5-hydroxytryptamine content of rabbit hearts and its release during in vitro perfusion. PMID- 4149743 TI - Evidence for catecholamine involvement in the suppression of locomotor activity due to hypoxia. PMID- 4149744 TI - Conopharyngine pseudoindoxyl, a new alkaloid from Tabernamontana pachysiphon Stapf. var cumminsii (Stapf.) H. Huber. PMID- 4149745 TI - Letter: Transmitter release by red back spider venom. PMID- 4149746 TI - Letter: Effect of emetine treatment on tissue transaminase activity. PMID- 4149748 TI - Letter: Effect of lithium carbonate and alpha-methyl-p-tyrosine on audiogenic seizure intensity. PMID- 4149747 TI - Letter: Effect of some lipid-soluble derivatives of amphetamine on amphetamine levels in rat brain. PMID- 4149749 TI - Letter: Ulcerogenic potential of indomethacin in arthritic and non-arthritic rats. PMID- 4149750 TI - Letter: 3-methoxyisoprenaline: a potent selective Uptake2 inhibitor. PMID- 4149751 TI - Letter: Monoamine tetrazolium reductase of rat heart mitochondria. PMID- 4149752 TI - Letter: More on the blockade of neural and exogenous noradrenaline in vascular tissue. PMID- 4149753 TI - Letter: Effect of phenylethanol on Pseudomonas aeruginosa. PMID- 4149754 TI - Letter: Effects of dopamine receptor stimulation and blockade on Ro 4-1284 induced enhancement of electroshock seizure. PMID- 4149755 TI - Letter: Nuclear magnetic resonance studies of cetomacrogol 1000-benzaldehyde propyl gallate interactions. PMID- 4149757 TI - [Does the collaboration between Nordic specialists need to be improved?]. PMID- 4149756 TI - Letter: The influence of chain length upon the activity of 5-hydroxytryptamine. PMID- 4149758 TI - Adrenergic-induced vascular adjustments--initial and escape reactions. II. Role of beta-adrenergic receptors within different sections of the isolated intestinal vascular bed. PMID- 4149759 TI - Adrenergic-induced vascular adjustments--initial and escape reactions. I. Influence of beta-adrenergic blocking agents on the intestinal circulation of the rat (in vivo). PMID- 4149760 TI - [Energy provision for epileptic discharge in generalized seizures]. PMID- 4149761 TI - [Pyrroxan therapy of patients with diencephalic epilepsy]. PMID- 4149762 TI - The subjective experience of perceptual and cognitive disturbances in schizophrenia. A review of autobiographical accounts. PMID- 4149763 TI - Diazepam on demand. Drug-seeking behavior in psychiatric inpatients. PMID- 4149764 TI - The subcellular distribution and properties of aldehyde dehydrogenases in rat liver. AB - 1. Kinetic experiments suggested the possible existence of at least two different NAD(+)-dependent aldehyde dehydrogenases in rat liver. Distribution studies showed that one enzyme, designated enzyme I, was exclusively localized in the mitochondria and that another enzyme, designated enzyme II, was localized in both the mitochondria and the microsomal fraction. 2. A NADP(+)-dependent enzyme was also found in the mitochondria and the microsomal fraction and it is suggested that this enzyme is identical with enzyme II. 3. The K(m) for acetaldehyde was apparently less than 10mum for enzyme I and 0.9-1.7mm for enzyme II. The K(m) for NAD(+) was similar for both enzymes (20-30mum). The K(m) for NADP(+) was 2-3mm and for acetaldehyde 0.5-0.7mm for the NADP(+)-dependent activity. 4. The NAD(+) dependent enzymes show pH optima between 9 and 10. The highest activity was found in pyrophosphate buffer for both enzymes. In phosphate buffer there was a striking difference in activity between the two enzymes. Compared with the activity in pyrophosphate buffer, the activity of enzyme II was uninfluenced, whereas the activity of enzyme I was very low. 5. The results are compared with those of earlier investigations on the distribution of aldehyde dehydrogenase and with the results from purified enzymes from different sources. PMID- 4149766 TI - Assay for glutamine synthetase activity. AB - The use of phosphoenolpyruvate plus pyruvate kinase as an ATP-generating system in the assay for glutamine synthetase activity via the formation of gamma glutamylhydroxamate from glutamate and hydroxylamine with crude tissue preparations is shown to give values far in excess of the true glutamine synthetase activity of the tissue. This is due to the generation of pyruvate, which reacts with hydroxylamine to give a compound that is chromogenic with the ferric chloride reagent used for measuring gamma-glutamylhydroxamate. PMID- 4149765 TI - Aromatic amino acid transaminase in rat intestine. AB - The transamination of aromatic l-amino acids (5-hydroxytryptophan, tryptophan, tyrosine, phenylalanine and kynurenine) was shown to be catalysed by enzyme preparations from rat small intestine. On the basis of the partial purification and characterization of these aromatic amino acid transaminases, it is suggested that rat small intestine contains several kinds of aromatic amino acid transaminases. PMID- 4149767 TI - The mechanism of the oxidation of ascorbate and MN2+ by chloroplasts. The role of the radical superoxide. PMID- 4149768 TI - [The effect of several neuromediators on succinate dehydrogenase activity]. PMID- 4149769 TI - [A comparative study of the luminescence of green and purple photosynthesizing bacteria in the region of 440 millimicrons]. PMID- 4149770 TI - [Possible paths for influencing the mechanism of experimental silicosis]. PMID- 4149771 TI - Prolonged drug-induced Parkinsonism. PMID- 4149772 TI - Late changes in the enzymatic activity of the neuroglia as a sequel to acute hydrogen cyanide poisoning. PMID- 4149773 TI - Regulation of tyrosine aminotrasferase activity in two liver-derived permanent cell lines. AB - The regulation of tyrosine aminotransferase (TAT) activity has been examined in two liver-derived heteroploid cell lines. One (hepatoma tissue culture cells [HTC]) was derived from a hepatoma, the other (rat liver culture cells [RLC]) was derived from normal liver. The two cell lines show the following striking similarities in the control of this specific protein: (a) The kinetics of TAT induction by dexamethasone phosphate (DxP) are similar in randomly growing cells of both lines; (b) During mitosis and early G(1) phase of the cell cycle TAT activity cannot be induced by DxP in either cell line; (c) 2-3 h into G(1), when both lines become sensitive to inducer, basal enzyme activity declines to a new steady-state level; (d) Preinduced cells collected in mitosis show approximately twice the level of TAT activity as fully induced, randomly growing cultures and this activity is maintained in early G(1) with or without the inducer; and (e) Inhibition of RNA synthesis by 5 microg/ml of actinomycin D in preinduced, synchronized cells allows TAT activity to remain at constitutive levels throughout G(1), even in the absence of inducer. These results are presented in support of a previously described model which states that glucocorticoid hormones exert posttranscriptional control of the synthesis of specific proteins in mammalian cells. PMID- 4149774 TI - Establishment of a clonal strain of hepatoma cells which maintain in culture the five enzymes of the urea cycle. PMID- 4149775 TI - Anticancer activity of zoanthids and the associated toxin, palytoxin, against Ehrlich ascites tumor and P-388 lymphocytic leukemia in mice. PMID- 4149776 TI - [Treatment of essential hypertension--its recent progress]. PMID- 4149777 TI - [Rheumatic fever with multiple vasculitis and idiopathic proliferative lymphadenitis (autopsy case of so-called "collagen diseases")]. PMID- 4149778 TI - [Two cases of malignant chorio-carcinomas in male patients (author's transl)]. PMID- 4149779 TI - [Hemodynamic effects of a new beta-receptor blocking agent in patients with myocardial infarct]. PMID- 4149780 TI - Some effects of experimental Fasciola hepatica infection in cattle on the serum activities of gamma-glutamyl transpeptidase and glutamic oxaloacetic transaminase. PMID- 4149781 TI - Metabolism of 2-hydroxy(4-14C)estradiol by rat liver microsomes. PMID- 4149782 TI - [Heterozygous NADH-methemoglobin reductase defect with methemoglobinemia in an infant (author's transl)]. PMID- 4149783 TI - [Problems particular to the correction of the bony or bony-chondral saddle nose (author's transl)]. PMID- 4149784 TI - Filariasis vectors in the Western Pacific region. PMID- 4149785 TI - Therapeutische Indikationen fur Agedal-Randolectil. PMID- 4149786 TI - Pneumococcal infections of the eye. PMID- 4149787 TI - Pharmacologic studies on propynyl dibenzazepine, a new alpha adrenergic blocker. PMID- 4149788 TI - Anticonvulsant testing with a new analeptic convulsant: N-sulfamoyl-hexahydro azepine (Sah 41-178). PMID- 4149789 TI - Chlorpromazine metabolism. VI. Adrenolytic and antiserotonergic activities of chlorpromazine and its various metabolites. PMID- 4149790 TI - Bronchospasmolytic activity of some prostaglandins in the guinea-pig. PMID- 4149791 TI - Hepatic coma in cirrhosis, portal hypertension, and following portacaval shunt. Its etiologies and the current status of its treatment. PMID- 4149792 TI - Development of carcinoma in regional enteritis. PMID- 4149793 TI - Comparison of the chronic and acute effects of D-lysergic acid diethylamide (LSD) treatment on rat brain serotonin and norepinephrine. PMID- 4149794 TI - Precocious induction of hepatic aniline hydroxylase and aminopyrine N-demethylase with hydrocortisone in neonatal rat. PMID- 4149795 TI - Reduction of chloral hydrate to trichloroethanol in brain extracts. PMID- 4149796 TI - Interaction of concanavalin A with the capsular polysaccharide of pneumococcus type XII and isolation of kojibiose from the polysaccharide. PMID- 4149797 TI - Conformation of porcine D-amino acid oxidase as studied by protein fluorescence and optical rotatory dispersion. PMID- 4149798 TI - Factors affecting the folding and association of flounder muscle glyceraldehyde-3 phosphate dehydrogenase, in vitro. PMID- 4149799 TI - Enhancing effect of glutamate on apparent serum gamma-glutamyltranspeptidase activity. PMID- 4149800 TI - The application of invertebrate tissue culture to the in vitro study of animal parasites. PMID- 4149801 TI - Cyclic AMP concentration in saliva of normal children and children with Downs syndrome. PMID- 4149802 TI - Some psychological factors in Parkinsonism. AB - Twenty-four Parkinsonism patients were compared with 'normal controls' and with another chronically disabled group, matched for age, sex distribution, and socioeconomic background, on measures of depression and some intellectual factors. A tendency to depression in the Parkinsonism sufferers was demonstrated together with an apparent specific intellectual deficit, for which a cause related to the motor disabilities of the disease is postulated. PMID- 4149803 TI - [Current aspects of chemotherapy of ischemic heart disease]. PMID- 4149804 TI - Ultrastructure of the glomerular basement membrane in long term renal allografts with transplant glomerular disease. PMID- 4149805 TI - [Traumatic asphyxia]. PMID- 4149806 TI - [Femoral neck and diaphyseal fracture on the same side in childhood]. PMID- 4149807 TI - [Primary osteosynthesis of hip fractures]. PMID- 4149808 TI - [A case of osteochondroma of the patella]. PMID- 4149809 TI - [Isolated dislocation of the 4th metatarsal bone]. PMID- 4149810 TI - [Closed isolated pancreatic injury in childhood]. PMID- 4149812 TI - [Knee dislocation without fracture]. PMID- 4149811 TI - [Rare late complications of pelvic fracture and urethral injury]. PMID- 4149813 TI - [Arthroplasty of the hand with silicone rubber prosthesis]. PMID- 4149814 TI - [Pulmonary changes caused by hyperbaric oxygenation]. PMID- 4149815 TI - [Diagnosis of maxillofacial injuries. I]. PMID- 4149817 TI - [Inadequate osteosynthesis of the humerus with iatrogenic radial nerve lesion]. PMID- 4149816 TI - [Therapy of maxillofacial injuries. II]. PMID- 4149818 TI - [Spinal injury as part of multiple injuries]. PMID- 4149819 TI - [Aneurysmal bone cyst]. PMID- 4149820 TI - [Osteochondrosis dissecans of the knee joint]. PMID- 4149821 TI - [The role of glucose analysis in the differential diagnosis of articular punctates]. PMID- 4149822 TI - [Acoustic phenomena of the knee]. PMID- 4149823 TI - [Pathological examination of degenerative changes in the shoulder joint]. PMID- 4149824 TI - [Traumatic rupture of the aorta diagnosed by x-ray]. PMID- 4149825 TI - [Rare agricultural injuries by impalement, with satisfactory outcome]. PMID- 4149826 TI - [Traumatic rupture of Meckel's diverticulum]. PMID- 4149827 TI - [Surgical treatment of habitual posterior dislocation of the shoulder joint]. PMID- 4149828 TI - [Traumatic pancreatic cyst in childhood]. PMID- 4149829 TI - [Posterior dislocation of the hip treated as central luxation]. PMID- 4149830 TI - [Roentgen signs of lateral dislocation of the shoulder]. PMID- 4149831 TI - [Results of meniscus surgery]. PMID- 4149832 TI - [Closed injuries of the trachea]. PMID- 4149833 TI - [Importance of physical exercise of the quadriceps muscle and of myotonography in the rehabilitation of athletes following meniscus operation]. PMID- 4149834 TI - [Effect of the graft vs. host reaction on the take and growth of normal and tumorous tissues]. PMID- 4149835 TI - Effect of trauma and hydrocortisone on liver tyrosine-alpha-ketoglutarate transaminase activity of rats adapted to noble-collip drum trauma. PMID- 4149836 TI - Analytical isotachophoresis in capillary tubes used for the separation of ions involved in the enzymatic transformation of glucose to 6-phosphogluconate. PMID- 4149837 TI - Cerebrospinal vascular wall lesions causing nervous symptoms in swine (Harding's cerebrospinal angiopathy). PMID- 4149838 TI - Improved purification, amino acid analysis and molecular weight of homogenous D amino acid oxidase from pig kidney. PMID- 4149839 TI - Purification and characterization of yeast thioredoxin reductase. PMID- 4149840 TI - Guanosine 5'-phosphate reductase of human erythrocytes. PMID- 4149841 TI - An interaction between S-adenosyl-L-methionine and pyridoxal 5'-phosphate, and its effect on Saccharomyces cerevisiae. PMID- 4149842 TI - Increased carbon tetrachloride hepatotoxicity, and its mechanism, after chronic ethanol consumption. PMID- 4149843 TI - [Mathematical evaluation of the reliability of operation of the biological component in a biotechnical system]. PMID- 4149844 TI - [Change in human immunological reactions during exposure to unfavorable microclimatic conditions in a sealed chamber]. PMID- 4149845 TI - Trans-synaptic enzyme induction. PMID- 4149846 TI - [Surreptitious acquisition of medical prescriptions. Criminologic studies on drugs and deliquency]. PMID- 4149847 TI - [New views on the physiopathology of peptic ulcer]. PMID- 4149848 TI - Antipsychotic agents. PMID- 4149849 TI - Meteorological effects on arthropods (including insects, ticks and mites) as vectors of human and animal diseases. PMID- 4149850 TI - Collar cells in planula and adult tentacle ectoderm of the solitary coral Balanophyllia regia (Anthozoa Eupsammiidae). PMID- 4149851 TI - [The obstetric-gynecological system in the USSR]. PMID- 4149852 TI - [Proceedings of the XXV General Meeting of the Japan Hematological society. 1]. PMID- 4149853 TI - On the relation of cyclic AMP to adrenergic receptors and sympathin. PMID- 4149855 TI - Fibromuscular dysplasia of the renal artery with medial dissection. A case simulating polyarteritis nodosa. PMID- 4149854 TI - Clinical conference: Hypertension. PMID- 4149856 TI - Fire-walking: a scientific investigation. PMID- 4149857 TI - Human infections with Dirofilaria, a filarial parasite of animals in Ceylon, with a brief review of recent cases. PMID- 4149858 TI - Hormonal regulation of protein degradation in hepatoma cells in tissue culture. PMID- 4149859 TI - Pathway from progesterone to 5 alpha-reduced C19 steroids not involving androstenedione and testosterone in immature rat testes in vitro. PMID- 4149860 TI - Adult endocardial fibroelastosis following electric shock. PMID- 4149861 TI - Repeat cesarean section in a low socio-economic population. PMID- 4149862 TI - Thymoma, erythroid hypoplasia and myasthenia gravis. Report of a case with ultrastructural study. PMID- 4149863 TI - Meckel's diverticulum. PMID- 4149864 TI - Acute yellow phosphorus rat poisoning. PMID- 4149865 TI - The new Supplemental Security Income Program. PMID- 4149866 TI - Electrocardiographic diagnosis of idiopathic pericarditis. PMID- 4149867 TI - The view box: aberrant papilla. PMID- 4149868 TI - It's up to you. PMID- 4149870 TI - [Proceedings of the 70th Annual Scientific Session of the Japanese Society of Internal Medicine]. PMID- 4149869 TI - Characteristics and caries experience of tetracycline-affected dentitions. PMID- 4149871 TI - Editorial: New antagonists excite an old histamine prospector. PMID- 4149872 TI - [Glucocorticoids and the liver (present-day state of the problem)]. PMID- 4149873 TI - [Clinical aspects of eczema in patients with the disorders of carbohydrate metabolism]. PMID- 4149875 TI - [Effect of vasoconstricting agents on hemodynamics under conditions of ganglion blockade during surgery and general anesthesia]. PMID- 4149874 TI - [Effect of griseofulvin on the activity of certain enzymes the serum polarograms in trichophytosis and microsporosis]. PMID- 4149876 TI - [Estimation of methyprylon in animal tissue (author's transl)]. PMID- 4149877 TI - [Hormonal and enzymatic regulation of glycide metabolism after trauma]. PMID- 4149878 TI - Bordetella pertussis as a beta-adrenergic blocking agent. PMID- 4149879 TI - Quantitative studies on anaphylaxis in guinea-pigs passively sensitized with homologous antibody. PMID- 4149880 TI - Alpha-alpha'-dipyridyl or ortho-phenanthroline stimulation of the soluble reduced nicotinamide adenine dinucleotide oxidase from Bacillus subtilis spores and dipicolinic acid inhibition of the stimulated enzymes. AB - Soluble reduced nicotinamide adenine dinucleotide oxidase activity in extracts of Bacillus subtilis spores was stimulated by the addition of not only flavine mononucleotide (FMN) or flavine adenine dinucleotide (FAD) but also alpha-alpha' dipyridyl or o-phenanthroline. These chelating agents showed stronger effect on the enzyme from spores than on that from vegetative cells. Activity stimulated by alpha-alpha'-dipyridyl or o-phenanthroline was inhibited by atabrine or dipicolinic acid, whereas FMN or FAD stimulation was inhibited only by atabrine. PMID- 4149881 TI - National Caries Program. Welcome and introduction. PMID- 4149882 TI - Immuno-regulatory role of spleen localizing thymocytes. PMID- 4149883 TI - Evaluation of T lymphocyte effector function in immunodeficiency diseases: abnormality in mitogen-stimulated interferon in patients with selective IgA deficiency. PMID- 4149884 TI - Tumor induction by immunologically activated murine leukemia virus: cellular immunity early in the graft-vs-host reaction. PMID- 4149885 TI - Interaction of anti-thymocyte serum with hematopoietic stem cells. I. Effects in vitro and in vivo. PMID- 4149886 TI - Psychophysiological patterns of response in schizophrenia. PMID- 4149887 TI - Comments on paper, "Psychophysiological patterns of response in schizophrenia". PMID- 4149888 TI - [Pneumococcal peritonitis]. PMID- 4149889 TI - Neuroendocrine communication. (Neurohormonal, neurohumoral, and intermediate). PMID- 4149890 TI - An MMPI scale for assessing death anxiety. PMID- 4149892 TI - [Proceedings: Labor inhibition in threatened abortion]. PMID- 4149891 TI - [New antihypertensive agents. 3. Propranolol]. PMID- 4149893 TI - [Hepatic and plasmatic gamma-glutamyl-transpeptidase during induction with phenobarbital: preliminary results]. PMID- 4149894 TI - The management of ulcerative colitis. PMID- 4149895 TI - [Principles and management of antihypertensive treatments]. PMID- 4149896 TI - [Symposium on present-day subjects of interest in cardiac arrhythmia. Introduction]. PMID- 4149897 TI - [Criteria for prevention of bronchiectasis based on its etiopathogenesis (report from a pneumologic meeting in Bologna]. PMID- 4149898 TI - [Changes in certain physiological indices under the influence of intellectual work in students]. PMID- 4149899 TI - Topical fluorides and dental caries: a review. PMID- 4149900 TI - [Abstracts of papers presented at the 46th General Meeting of the Japanese Biochemical Society]. PMID- 4149901 TI - Time series analysis of mosquito population data. PMID- 4149902 TI - A forecasting model for mosquito population densities. PMID- 4149903 TI - Laboratory transmission of Lacrosse encephalitis virus by several species of mosquitoes. PMID- 4149904 TI - Field studies on mosquito-arbovirus relationships in Iowa, 1971. PMID- 4149906 TI - [Antihistaminic-corticoid combinations in allergy]. PMID- 4149907 TI - [A comparative analysis of the behavior of L forms of bacteria and mycoplasma in cell cultures]. PMID- 4149905 TI - [Hyperbaric oxygenation in patients with alveolar hypoventilation (author's transl)]. PMID- 4149908 TI - Cardiac arrhythmias of central nervous system origin: possible mechanism and suppression. PMID- 4149909 TI - Health action '72. Brief to the Minister of National Health and Welfare: collective cure for the health care system. PMID- 4149910 TI - [Abstracts of reports presented at Congresses of the Japan Neurological Society]. PMID- 4149911 TI - Correspondence between Mini-Mult and standard MMPI scale scores in patients with neurological disease. PMID- 4149912 TI - Reliability and scale equivalence of the Mini-Mult and MMPI. PMID- 4149913 TI - Depression and suicidality. PMID- 4149914 TI - Personality factors associated with over- and undercontrolled offenders. PMID- 4149915 TI - Coronary aneurysm: isolated necrotizing angitis of a major coronary artery. Report of a case. PMID- 4149916 TI - Sympathetic beta adrenergic blockade in the preoperative treatment of hyperthyroidism. PMID- 4149917 TI - [Effects in humans of a new beta adrenergic receptor blocking agent on tachycardia induced with isoprenaline]. PMID- 4149918 TI - How do chemical substances affect the environment? PMID- 4149919 TI - Biodegradability. PMID- 4149920 TI - A discussion on the assessment of the environmental impact of chemical substances. To what extent can molecular structure point to potential hazards? PMID- 4149921 TI - Carcinogenic hazards in natural and man-made environments. PMID- 4149922 TI - The approach of industry to the assessment of environmental hazards. PMID- 4149923 TI - A multi-national company, the public and the environment. PMID- 4149924 TI - Environmental information and data handling. PMID- 4149925 TI - The stimulant action of noradrenaline (alpha-action) on guinea-pig myometrium compared with that of acetylcholine. PMID- 4149926 TI - Have the Bedouin a special 'desert' physiology? PMID- 4149927 TI - The evolution of the retinotectal map during development in Xenopus. PMID- 4149928 TI - Haemodynamic production of lipid deposition, intimal teats, mural dissection and thrombosis in the blood vessel wall. PMID- 4149929 TI - Intraerythrocytically administered tubercidin (7-deazaadenosine) and immune protection of mice. PMID- 4149930 TI - Uric acid excretion as an indicator of the amino acid requirement of chicks. PMID- 4149931 TI - Graft-versus-host reactions in isohistogenic rats. Frequency and donor-host origin of IgG-containing cells in local intrarenal graft-versus-host reactions. PMID- 4149932 TI - [Adaptation of enzymes according to stability]. PMID- 4149933 TI - [Arthrodeses for elimation of post-traumatic middle-foot damages]. PMID- 4149934 TI - [Chopart exarticulation using tenomyoplasty]. PMID- 4149936 TI - Pediatric radiology. PMID- 4149935 TI - Gamma-glutamyl transpeptidase and 5'-nucleotidase. Comparison as diagnostics for hepatic disease. PMID- 4149937 TI - The effects of fluroxene and enflurane on contractile performance of isolated papillary muscles from failing hearts. PMID- 4149938 TI - [Drug therapy using sulfonamides in dentistry, stomatology and gnathology. 4. Bacteriologic and morphologic-pathologic principles in the use of sulfonamides]. PMID- 4149939 TI - [Caries prevention using fluoride varnish (Duraphat)--clinical results and experiences]. PMID- 4149940 TI - [State of the sympathetic-adrenal system in congestive cardiac insufficiency]. PMID- 4149941 TI - [Effect of mental work with varying degrees of nervous and emotional stress on the cardiovascular system]. PMID- 4149942 TI - Antiparkinson drugs as causal agents in tardive dyskinesia. PMID- 4149943 TI - Letter: Beta-blocking drugs. PMID- 4149944 TI - [Importance of prophylactic vitaminization of the food ration of persons working under emotional stress for normalizing changes in lipid metabolism]. PMID- 4149945 TI - Role of the alpha-receptor in the control of noradrenaline release from sympathetic nerves. PMID- 4149946 TI - Ethanol administration and the relationship of malonyl-coenzyme A concentrations to the rate of fatty acid synthesis in rat liver. AB - 1. The effect of ethanol on liver fatty acid synthesis was studied in vivo in 24h starved and ;meal-fed' rats (i.e. fed for 3h per day and not ad libitum). 2. In the fed animal (3)H(2)O was incorporated into fat at a rate of 0.46mumol of C(2) units/min per g wet wt. of liver. Administration of either ethanol (3.2g/kg) or equicaloric amounts of glucose had no effect on the rate of (3)H(2)O incorporation into lipid. 3. In the 24h-starved animal, administration of the same dose of ethanol produced an increase in the rate of (3)H(2)O incorporation from 0.06 to 0.12mumol of C(2) units/min per g fresh wt. after 3h whereas [malonyl-CoA] increased from 0.006 to 0.009mumol/g. Glucose given in amounts equicaloric to ethanol was significantly more lipogenic, increasing both the (3)H(2)O incorporation from 0.06 to 0.20mumol of C(2) units/min per g and the malonyl-CoA content from 0.006 to 0.013 mumol/g wet wt. at 3h. 4. The decrease in the redox state of free cytoplasm NAD or NADP couples or the changes in content of citrate, glucose 6-phosphate and pyruvate of liver after ethanol administration had no measurable effect on the rate of fatty acid synthesis in vivo. 5. Under the conditions of the experiments there was no significant difference, among any of the groups, in the activity of liver fatty acid synthetase measured in vitro. A double-reciprocal plot of the rate of (3)H(2)O incorporation and the total tissue malonyl-CoA concentrations showed a striking relationship. It has been concluded that the rate of fatty acid synthesis in vivo is determined principally by the V(max.) of fatty acid synthetase and the concentration of free malonyl-CoA. 6. It has also been concluded that under the conditions of the present study, the synthesis of fatty acids de novo is unlikely to be an important factor in the increased liver lipid content associated with ethanol administration. PMID- 4149948 TI - Studies on possible routes of ammonium assimilation in soybean root nodule bacteroids. PMID- 4149947 TI - Metabolic adaptations during lactogenesis. Fatty acid and lactose synthesis in cow mammary tissue. AB - 1. Mammary-tissue biopsies were obtained from multiparous cows at 30 and 7 days pre partum and 7 and 40 days post partum. Investigations of the effect of lactogenesis on fatty acid and lactose synthesis involved measurements of biosynthetic capacity (tissue-slice incubations in vitro) and activities of relevant enzymes. 2. Fatty acid synthesis from acetate increased over 20-fold from 30 days pre partum to 40 days post partum. Changes in the lipogenic capacity of mammary-tissue slices more closely paralleled increases in the activities of acetyl-CoA carboxylase (EC 6.4.1.2) and acetyl-CoA synthetase (EC 6.2.1.1) than of other enzymes involved in acetate incorporation into fatty acids or in NADPH generation. 3. Lactose biosynthesis by mammary-tissue slices, lactose synthetase activity (EC 2.4.1.22) and alpha-lactalbumin concentration were all negligible at 30 days pre partum but increased 2.5-4-fold between 7 days pre partum and 40 days post partum. Phosphoglucomutase (EC 2.7.5.1), UDP-glucose pyrophosphorylase (EC 2.7.7.9) and UDP-glucose 4-epimerase (EC 5.1.3.2) had substantial activities at 30 days pre partum and increased less dramatically during lactogenesis. 4. Results are consistent with acetyl-CoA carboxylase and perhaps acetyl-CoA synthetase representing the regulatory enzyme(s) in fatty acid synthesis, with lactose synthetase (alpha-lactalbumin) serving a similar function in lactose biosynthesis. PMID- 4149950 TI - Using T-groups to train American Indians as physician assistants. PMID- 4149949 TI - Isolation of mutants of Bacillus stearothermophilus blocked in catabolic function. PMID- 4149952 TI - Diet and dental caries: dental caries incidence and the consumption of ready-to eat cereals. PMID- 4149951 TI - Regulation of gene expression by hormones during the mammalian cell cycle. PMID- 4149953 TI - Graded responses in ciliary activity of ctenophores compared with the "staircase" of cardiac muscle. PMID- 4149954 TI - Distal condylar fractures of the cannon bone in the horse. PMID- 4149956 TI - Some aspects of the immunology of Hodgkin's disease. PMID- 4149955 TI - [Generalized acute allergic reactions to bee and wasp stings: evolution and duration of specific hyposensitization with intracutaneous administration of extracts of the allergens]. PMID- 4149957 TI - Immunofluorescent studies of lymphoid tissue in Hodgkin's disease. PMID- 4149958 TI - A new concept of immunoregulation and its application to leukemia and lymphoma. PMID- 4149959 TI - Symposium: Immunological aspects of Hodgkin's disease. Concluding remarks. PMID- 4149960 TI - Stress induced inhibition of jejunal crypt cell proliferation. PMID- 4149961 TI - [Clinico-immunologic characteristics of different forms of complications following smallpox vaccination in children]. PMID- 4149962 TI - [XXXY syndrome. A case and review of the literature]. PMID- 4149963 TI - Mechanism of calcium induction of Renilla bioluminescence. Involvement of a calcium-triggered luciferin binding protein. PMID- 4149964 TI - [Protein synthesis by isolated mitochondria from the yeast Saccharomyces cerevisiae]. PMID- 4149965 TI - [A study of Micrococcus lysodeikticus membrane respiratory chain complexes by the gel electrophoresis method]. PMID- 4149966 TI - [Mechanisms of the conservation of energy in the mitochondrial membrane]. PMID- 4149967 TI - [NADP analogs, inhibitors of dihydrofolate reductase]. PMID- 4149968 TI - [Acid-soluble nucleotides of rat liver mitochondria and submitochondrial fragments]. PMID- 4149969 TI - [Action of catalase, peroxidase and hydrogen peroxide on the light reactions of isolated pea chloroplasts]. PMID- 4149970 TI - [Study of the nicotinamide coenzymes in the process of the formation and development of the fruiting bodies on the mycelium of the fungus Lentinus tigrinus Fr]. PMID- 4149971 TI - [Electron transport in rat liver microsomes. The role of ionic interactions]. PMID- 4149972 TI - [Action of ultrasonic treatment on the membrane and respiratory chain of Micrococcus lysodeikticus]. PMID- 4149973 TI - The Stokes-Adams syndrome. PMID- 4149974 TI - Beta adrenergic blocking drugs in the treatment of cardiac arrhythmias. PMID- 4149975 TI - Combination antihypertensive therapy. PMID- 4149976 TI - Editorial: A new interpretation of the major histocompatibility gene complexes of man and mouse. PMID- 4149977 TI - Studies on immunological paralysis. VI. Thymic-independence of tolerance and immunity to type 3 pneumococcal polysaccharide. PMID- 4149978 TI - Immunity and tolerance: a unified concept. PMID- 4149979 TI - Selected topics on the biochemistry of spermatogenesis. PMID- 4149981 TI - Editorial: New types of health professionals for developing and developed countries. PMID- 4149980 TI - Effects of some beta adrenergic blocking agents on tremorine induced tremor, hypothermia and cholinergic effects in rats. PMID- 4149982 TI - The role of the symbiotic algae of Plexaura homomalla in prostaglandin biosynthesis. PMID- 4149983 TI - Ultraviolet spectrophotometry of phenothiazine derivatives and analogs. PMID- 4149984 TI - Structure and function of D-amino acid oxidase. VII. Interaction of hydrophobic probes with D-amino acid oxidase. PMID- 4149985 TI - Two different NADH dehydrogenases in respiration of Rhodospirillum rubrum chromatophores. PMID- 4149986 TI - The effects of personality tests on state and trait anxiety. PMID- 4149987 TI - Concurrence of psychiatric diagnosis and psychological diagnosis based on the MMPI. PMID- 4149988 TI - Differential misdiagnosis of blacks and whites by the MMPI. PMID- 4149989 TI - MMPI X and Zero items in a psychiatric outpatient group. PMID- 4149990 TI - [Seminar on malignant diseases of the urinary tract. London, 26 February 1972]. PMID- 4149991 TI - Polyps of the colon. PMID- 4149992 TI - Foot infection in the elderly. PMID- 4149993 TI - Metabolism and functions of cyclic AMP in nerve. PMID- 4149994 TI - [Oxidoreductase activity in long term cultures of dissociated trigeminal ganglia cells of the chick embryo]. PMID- 4149995 TI - [Histochemical studies of explant cultures from cerebral cortex of newborn rats]. PMID- 4149996 TI - New drugs of 1970. PMID- 4149997 TI - Multimodality treatment of the hyperkinetic child. PMID- 4149998 TI - Letter: The effect of benztropine mesylate on plasma levels of butaperazine maleate. PMID- 4149999 TI - A human model of coal tar acne. PMID- 4150000 TI - Antihypertensive and hemodynamic properties of the new beta adrenergic blocking agent timolol. PMID- 4150001 TI - Direct arterial pressure and the electrocardiogram in unrestricted patients with angina pectoris. PMID- 4150002 TI - Need for statutory legitimation of the roles of physician's assistants. AB - A significant constraint on new categories of health manpower is the absence of statutory legitimation of their roles. Licensure has been evolved as an effort to assure high-quality health care, but recently it has been a barrier to effective and innovative use of manpower. Medical and Nurse Practice Acts generally define the practices of medicine and nursing, but they do not define clearly the scope of these practices. Thus, these acts subject physicians to undue risks in delegating responsibilities and Type A assistants (nurses or non-nurses with special training) to undue risks in accepting those functions. Furthermore, only vague guidelines are provided to protect the public and to assure adequate quality control. To date, 35 States have enacted legislation to provide statutory legitimation of Type A assisants and to permit physicians to delegate appropriate responsibilities to new types of health manpower. It is hoped that this legislation will diminish barriers to effective use of health manpower. PMID- 4150003 TI - [Neurovegetative problems in newborn infants]. PMID- 4150004 TI - [Nonspecific bacterial respiratory infections in patients suffering from cancer of the lung (author's transl)]. PMID- 4150005 TI - [The value of segment specific enzymes in urine in toxicological and clinico pharmacological studies]. PMID- 4150006 TI - [Heart rate as a parameter of phase I studies]. PMID- 4150007 TI - [Comparative studies on propranolol and practolol]. PMID- 4150008 TI - [Dose-response relationship of beta-adrenergic blocking agents]. PMID- 4150009 TI - [Stimulation of insulin secretion by tolbutamide. Studies on experimental diabetes]. PMID- 4150010 TI - Effect of handling in infancy on responsiveness of adrenal tyrosine hydroxylase in maturity. PMID- 4150011 TI - Oxidative metabolism of carbon disulphide by the rat. Effect of treatments which modify the liver toxicity of carbon disulphide. PMID- 4150012 TI - Omega-oxidation of stearic acid in the normal, starved and diabetic rat liver. PMID- 4150013 TI - Enzymatic characteristics of CO-sensitive 26-hydroxylase system for 5beta cholestane-3 alpha, 7 alpha, 12 alpha-triol in rat-liver mitochondria and its intramitochondrial localization. PMID- 4150014 TI - Difference between the lymph node response to injection of autosensitized T lymphocytes and that in a graft-versus-host reaction. PMID- 4150015 TI - [Effect of inderal and trasicor on the function of external respiration in chronic coronary insufficiency]. PMID- 4150016 TI - Editorial: The real gap between bench and bedside. PMID- 4150017 TI - The effect of beta-adrenergic blocking agents on the rat adrenal phenylethanolamine-N-methyltransferase activity. PMID- 4150018 TI - Evaluation of beta-adrenolytic properties of N,N'-bis-(3-(p-methoxyphenoxy)-2 hydroxypropyl)-ethylenediamine and its N,N'-dimethyl derivative. PMID- 4150019 TI - [Limitations of the nonimmune lymphocyte transfer test as a method of selecting donors for transplantation (a review of the literature)]. PMID- 4150020 TI - Transformation by simian virus 40 of spleen cells from a hyperimmune rabbit: evidence for synthesis of immunoglobulin by the transformed cells. AB - Spleen cells derived from a rabbit hyperimmunized with a Type III pneumococcal vaccine were exposed to simian virus 40 in vitro. After 114 days, transformed cells growing on the surface of one culture dish were observed and a cell line was established. The transformed cells had a morphology characteristic of cells transformed by simian virus 40, contained the simian virus 40-specific T antigen, and yielded infectious simian virus 40 upon cultivation with indicator cells in the presence of Sendai fusion factor. Transformed cells incorporated labeled amino acid into protein with the antigenic properties of rabbit immunoglobulin G. PMID- 4150021 TI - Transformation by simian virus 40 of spleen cells from a hyperimmune rabbit: demonstration of production of specific antibody to the immunizing antigen. AB - Extracts of spleen cells obtained from a rabbit hyperimmunized with Type III pneumococcal vaccine and transformed with simian virus 40, were subjected to agarose gel electrophoresis in the presence of an [(125)I]S3 polysaccharide protein conjugate. Binding of radioactivity in the gamma globulin region was observed. Extracts and media obtained from labeled cell cultures contained a protein that bound to an S3, but not to an S8 or inactivated S3 immunoadsorbent. After elution, the bound protein showed a single band on isoelectric focusing which corresponded in isoelectric point to one of the serum anti-S3 antibodies of the donor rabbit. These observations strongly suggest that a normal committed lymphoid cell may be brought into continuous culture by virus transformation and yet retain its ability to synthesize specific antibody. PMID- 4150022 TI - Formation of 5-oxoproline from glutathione in erythrocytes by the gamma glutamyltranspeptidase-cyclotransferase pathway. AB - gamma-Glutamyltranspeptidase activity was demonstrated in the membrane fraction of rabbit erythrocytes. The activity observed (with glutathione and various amino acid acceptors) was similar in magnitude to that of the gamma glutamylcyclotransferase and gamma-glutamylcysteine synthetase activities found in the soluble fraction of the cell. No transpeptidase activity was observed with either gamma-glutamyl p-nitroanilide or oxidized glutathione in contrast to the rabbit-kidney enzyme for which these compounds and glutathione serve as substrates. Erythrocyte suspensions and hemolysates formed 5-oxoproline (pyroglutamate; pyrrolidone carboxylate); the rate of 5-oxoproline formation from glutathione by hemolysates was increased by addition of methionine. The findings indicate that 5-oxoproline is an end-product of glutathione metabolism in erythrocytes, and that 5-oxoproline passes out of the erythrocyte and is metabolized in other tissues. The observed rate of 5-oxoproline formation is consistent with the conclusion that the gamma-glutamyltranspeptidase cyclotransferase pathway, together with the synthesis of glutathione from glycine, cysteine, and glutamate, account for a large fraction of the observed amino-acid turnover of erythrocyte glutathione. PMID- 4150023 TI - Inhibition of bacterial growth by beta-chloro-D-alanine. AB - The D- and L-isomers of beta-chloroalanine inhibit the growth of Diplococcus pneumoniae, Streptococcus pyogenes, Bacillus subtilis, and Escherichia coli. With pneumococcus the inhibition by beta-chloro-D-alanine is completely prevented by either D-alanine or D-alanyl-D-alanine, while L-alanine is not effective in preventing the inhibition. The inhibition of growth by beta-chloro-L-alanine is not affected by D-alanine and is only partially prevented by high concentrations of L-alanine. The intracellular free alanine in untreated E. coli and B. subtilis is about 95% in the D-configuration while the free intracellular alanine in both organisms after treatment with beta-chloro-D-alanine is predominantly the L isomer. These results suggested that the beta-chloroamino acid inactivates alanine racemase (EC 5.1.1.1). Indeed, when extracts of E. coli or B. subtilis were treated with beta-chloro-D-alanine, the activities of alanine racemase and of D-glutamate-D-alanine transaminase were found to be 90-95% inhibited. Studies with mice have shown that beta-chloro-D-alanine is an effective antibacterial agent in vivo againt D. pneumoniae, S. pyogenes, and E. coli. PMID- 4150024 TI - Ataxia-telangiectasia (Louis Bar syndrome): with special reference to findings in the peripheral nervous system. PMID- 4150025 TI - Gamma-glutamyl transpeptidase in brain capillaries: possible site of a blood brain barrier for amino acids. AB - A fraction containing capillaries and rich in gamma-glutamyl transpeptidase was isolated from homogenates of bovine brain cortex by density gradient centrifugation. The enzyme was localized in the endothelial cells by a histochemical procedure. gamma-Glutantyl transpeptidase may function in the transfer of some amino acids across the blood-brain barrier. PMID- 4150026 TI - Gel chromatographic purification of rabies virus on wide-pore glass. PMID- 4150027 TI - Concentration of echoviruses by polyethylene glycol. PMID- 4150028 TI - Interferon in young and aged chick embryo cell cultures infected with herpes simplex and pseudorabies viruses. PMID- 4150029 TI - Paralytic sequelae and immunologic response of infant mice after infection with viruses of the Tacaribe group. PMID- 4150030 TI - Interferon induction by, and antiviral effect of poly (rI)--poly (rC) in experimental viral infection. PMID- 4150031 TI - Interferon induction by detoxicated bacterial endotoxins. PMID- 4150032 TI - Genetic interaction between two influenza A-WS virus mutants. 3. Capacity of WS NWS recombinants to reproduce in various cell systems. PMID- 4150033 TI - Survival of small amounts of Coxsackie A4 virus in Danube river water under laboratory conditions. PMID- 4150034 TI - Susceptibility of Anopheles gambiae mosquito cell line (MOS 55) to some arboviruses. PMID- 4150035 TI - Changes in isoelectric points of chromatin deoxyribonucleoproteins from Krebs II cells after infection with encephalomyocarditis virus. PMID- 4150036 TI - Thoracic duct lymph and blood of mice at early stages of Tahyna and Semliki Forest virus infections. PMID- 4150037 TI - Comparison of antibody-binding and antibody-inducing capacities of phase I and phase II Coxiella burneti antigens. PMID- 4150038 TI - [Photoinactivation of NAD glucohydrolase from rabbit heart]. PMID- 4150039 TI - [Histological and histo-chemical investigations of rat kidneys after the administration of Chlormerodrin 203Hg and Unithiol (author's transl)]. PMID- 4150040 TI - [Radiographic demonstration of a testicular neoplasm in cryptorchism]. PMID- 4150041 TI - [Carbromal-intoxication among children (author's transl)]. PMID- 4150042 TI - [New symptomatic therapeutics]. PMID- 4150043 TI - Mechanisms involved in the trans-synaptic increase of tyrosine hydroxylase and dopamine-beta-hydroxylase activity in sympathetic ganglia. PMID- 4150046 TI - Effect of prostaglandins on fatty acid metabolism in lung. PMID- 4150044 TI - Effect of duration and frequency of stimulation on the presynaptic inhibition by alpha-adrenoceptor stimulation of the adrenergic transmission. PMID- 4150047 TI - [Prof. Georg H. H. Henneberg, M. D., 65 years old]. PMID- 4150048 TI - [Publications of Prof. Georg Henneberg, M.D]. PMID- 4150049 TI - [Studies on the resistance of "fixed" rabies virus against the most important active components of disinfectants (author's transl)]. PMID- 4150050 TI - [Comparative studies on the use of ion-exchange resins and "liquoid" containing media for blood cultures (author's transl)]. PMID- 4150051 TI - [Comparative investigations on the activity of ciclacillin, ampicillin and carbenicillin (author's transl)]. PMID- 4150052 TI - [Polyoma virus dose-response studies in rats. I. On the relationship between oncogenicity and antigenicity (author's transl)]. PMID- 4150053 TI - [Cryptococcosis. A contribution to the identification of Cryptococcus neoformans isolated from clinical specimens (author's transl)]. PMID- 4150054 TI - [The parasite index and its importance in Asian refugees from Uganda (author's transl)]. PMID- 4150055 TI - [A simplified method for investigation of colicinogeny (author's transl)]. PMID- 4150056 TI - Photometric method for determination of doubly specific influenza antibody. PMID- 4150057 TI - [The development of antibiotics resistance among salmonella bacteria of animal origin in the Federal Republic of Germany and West Berlin. 1st communication: a comparison between the years of 1961 and 1970-71 (author's transl)]. PMID- 4150058 TI - [The development of antibiotics resistance among salmonella bacteria of animal origin in the Federal Republic of Germany and West Berlin. 2nd communication: 1971 annual report (author's transl)]. PMID- 4150060 TI - [Oral immunization with non-viable micro-organisms or their antigens. 17. Communication: time kinetics of the nonspecific activity of phagocytes from peritoneal macrophages (author's transl)]. PMID- 4150059 TI - [Oral immunization with non-viable micro-organisms or their antigens. 16. Time kinetics of the protection after vaccination (author's transl)]. PMID- 4150061 TI - [Early detection of prenatal infections in newborns (author's transl)]. PMID- 4150062 TI - [Rabies in dogs experimentally infected with street virus and immunized with Flury LEP virus thereafter (author's transl)]. PMID- 4150064 TI - [The antiviral effect of tilorone HCl derivatives against TBE in mice (author's transl)]. PMID- 4150063 TI - Studies on group A (phage tail) bacteriocins of Serratia marcescens. I. Phenotypic variation of producer and indicator strains. PMID- 4150065 TI - [Immunoreaction in spleen and Peyer's patches after intravenous application of E. coli antigen in comparison of the agar plaque technique with the bacteriolytic plaque assay in agar (author's transl)]. PMID- 4150066 TI - [Identification of Arizona bacteria. A contribution to the problem of salmonella infections among reptiles and amphibians in zoological gardens (author's transl)]. PMID- 4150067 TI - [Phosphatase-reagent for quick identification of Clostridium perfringens (author's transl)]. PMID- 4150068 TI - Identification of 38 mycoplasma strains isolated from the vagina of dogs. PMID- 4150069 TI - [Influence of staphylococci and Pseudomonas aeruginosa on L-forms of Proteus mirabilis (author's transl)]. PMID- 4150070 TI - [Bacteriophages of Propionibacterium acnes (author's transl)]. PMID- 4150071 TI - [Epidemiological observations concerning Candida fungemia in patients with indwelling venous catheters (author's transl)]. PMID- 4150072 TI - [Survey with human sera from West Cameroon (author's transl)]. PMID- 4150073 TI - [Serologic investigations of sera of wild and domestic animals and of man for ornithosis (author's transl)]. PMID- 4150074 TI - [Cytotoxic activity of Pseudomonas aeruginosa with regard to lecithinase, lipase, proteinase, hemolysine, and surface activity (author's transl)]. PMID- 4150075 TI - [Incidence of swimmers' itch in Austria and possibilities of its control (author's transl)]. PMID- 4150076 TI - [Incidence of colicinogenic E. coli in the gut flora of healthy pigs (author's transl)]. PMID- 4150077 TI - [The influence of chemical immunosuppression on the protective efficacy of vaccinations (author's transl)]. PMID- 4150078 TI - [Differentiation of facultatively anaerobic Actinomycetaceae by an indirect fluorescent antibody technique (author's transl)]. PMID- 4150079 TI - [Classification as a separate equine herpesvirus of isolate 53-69 from equine coital exanthema (author's transl)]. PMID- 4150080 TI - [Monosminergic influences of the caudate nucleus on the escape reaction in rats]. PMID- 4150081 TI - Linear theory of enzymatic chains; its application for the analysis of the crossover theorem and of the glycolysis of human erythrocytes. PMID- 4150082 TI - Bimodality and lateral asymmetry of skin conductance orienting activity in schizophrenics: replication and evidence of lateral asymmetry in patients with depression and disorders of personality. PMID- 4150084 TI - Medical assistants. Can AAMA help you? PMID- 4150085 TI - [Laboratory and clinical evaluation of clindamycin-2-palmitate in pediatric field (author's transl)]. PMID- 4150083 TI - Health centre practice in Livingston New Town. PMID- 4150086 TI - Inhibition by tetrahydroharmane compounds of 5-hydroxytryptamine and histamine uptake in rabbit blood platelets. PMID- 4150087 TI - Inhibition of monoamine uptake in synaptosomes by tetrahydroharmane and tetrahydroisoquinoline compounds. PMID- 4150088 TI - Does burimamide inhibit gastric acid secretion by a release of catecholamines? PMID- 4150090 TI - Increased synthesis of adrenomedullary catecholamines induced by caffeine and theophylline. PMID- 4150091 TI - [Letter: Diet and drugs in arterial hypertension]. PMID- 4150089 TI - On the mechanism of the synergistic effect of perazine and hexobarbital. PMID- 4150092 TI - Another utilization of MESA in the evaluation-grading of a class of Medex trainees. PMID- 4150093 TI - [A cytochemical study of the hemogregarins of Armenian reptiles. 3. The dehydrogenase activity of hemogregarins from the peripheral blood of rock lizards and in infected erythrocytes]. PMID- 4150094 TI - [Possible artifacts in the histochemical determination of soluble dehydrogenases bound to pyridine nucleotides]. PMID- 4150095 TI - [Evaluation of methods of treating cows for endometritis]. PMID- 4150096 TI - Objective diagnostic tests and measures. PMID- 4150097 TI - The effects of steroid and gonadotrophic hormones in vitro on the metabolic activity of normal and cryptorchid rat testicular tissues. PMID- 4150098 TI - [Haemodialysis in intoxication with hypnotics (author's transl)]. PMID- 4150099 TI - Enzymatic and mechanical requirements for the dissociation of cortical cells from rat adrenal glands. PMID- 4150100 TI - Further evidence of the similarity of microtubule protein from mitotic apparatus and sperm tail of the sea urchin, as a substrate in thiol-disulfide exchange reaction. PMID- 4150101 TI - Mechanism of adrenergic neuron blocking effects of propranolol & pronethalol. PMID- 4150103 TI - The use of allied health workers by general practitioners in various situations. PMID- 4150102 TI - Comparison of oral health in four Canadian Indian communities. PMID- 4150104 TI - Graft-versus-host disease. PMID- 4150105 TI - Norepinephrine-sensitive adenylate cyclases in rat brain: relation to behavior and tyrosine hydroxylase. AB - Responses of norepiniephrine sensitive adeniosinie 3',5'-monophosphate (cyclic AMP)-generating systems in combined midbrain-striatal slices of four rat strains correlate positively with spontaneous behavioral activity and negatively with levels of midbrain and striatal tyrosine hydroxylase. Responses of cerebral cortical norepinephrine-sensitive cyclic AMP systems correlate negatively with spontaneous behavioral activity antd positively with midbrain and striatal tyrosine hydroxylase. Such correlations were not found with responses of the cyclic AMP- generatinlg systems to isoproterenol, adenosine. veratridine or of an adenosne and norepinephrine combination. PMID- 4150106 TI - Experimental selection of influenza virus mutants (subtype A0 and A1): haemagglutinin. PMID- 4150107 TI - [The detrimental effect of formaldehyde upon the immunological efficacy of Hempt rabies vaccine (author's transl)]. PMID- 4150108 TI - [On polyomavirus inhibitors. I. In vitro experiments (author's transl)]. PMID- 4150109 TI - [Vaccinia in humans caused by generalized infection of a circus elephant (author's transl)]. PMID- 4150110 TI - Studies on the mercury resistance of staphylococci. PMID- 4150111 TI - [Simplified diagnosis of Streptococcus dysgalactiae (author's transl)]. PMID- 4150112 TI - [Typing of Pseudomonas aeruginosa by means of titrated pyocines (author's transl)]. PMID- 4150113 TI - [Taxonomy and nomenclature of Pseudomonas cepacia (author's transl)]. PMID- 4150114 TI - [Caprolactamase activity in rapidly growing mycobacteria (author's transl)]. PMID- 4150115 TI - Actinobacillus lignieresii human infection. PMID- 4150116 TI - [Studies on the haemolytic properties of leptospira with the application of a radioisotopic method (author's transl)]. PMID- 4150117 TI - [Tribrom-nitromethan--a new disinfectant of high efficiency (author's transl)]. PMID- 4150118 TI - [Kinetics of infection with toxoplasma gondii, rubella-, mumps- and cytomegalovirus (author's transl)]. PMID- 4150119 TI - Effect of dipicolinic acid on the haemolysis of human red blood cells. PMID- 4150120 TI - [Microbiological indicators of sterilization. General principles (author's transl)]. PMID- 4150121 TI - Regional lymph node response in rats to injection of semi-allogeneic lymphocytes. Time, weight, dose, and histocompatibility relations. PMID- 4150122 TI - Regulation of glutamine synthetase adenylylation and deadenylylation by the enzymatic uridylylation and deuridylylation of the PII regulatory protein. PMID- 4150123 TI - Purification and properties of two ferredoxins from the nitrogen-fixing bacterium Bacillus polymyxa. PMID- 4150124 TI - Studies of mitochondrial energy systems during embryogenesis in the rat. PMID- 4150125 TI - Kinetic studies of a NADP+-specific isocitrate dehydrogenase from Salmonella typhimurium. Purification and reaction mechanism. PMID- 4150126 TI - Lipid peroxidation and the degradation of cytochrome P-450 heme. PMID- 4150127 TI - Gastric aspiration and lavage. PMID- 4150128 TI - The use of emetics in poison ingestion. PMID- 4150129 TI - Drug alert--syrup of ipecac. PMID- 4150130 TI - The N-hydroxylation of phentermine (2-methyl-2-amino-1-phenylpropane). Properties of the enzyme system. PMID- 4150131 TI - Disposition and anticonvulsant activity of bromazepam in mice. PMID- 4150132 TI - Isolation of pentaerythritol nitrates and their glucuronides. PMID- 4150133 TI - Denitration of unconjugated and conjugated pentaerythritol nitrates by rat liver cytosol. PMID- 4150134 TI - Metabolism of dihalomethanes to carbon monoxide. I. In vivo studies. PMID- 4150135 TI - Oxygenated norethindrone derivatives from incubation with beagle liver. Structure, synthesis, and biological activity. PMID- 4150136 TI - Stereoselective biotransformations of dl-norgestrel and its enantiomers in the African green monkey. PMID- 4150137 TI - The acetylator phenotype of patients with systemic lupus erythematosus. PMID- 4150138 TI - The role of gut flora in the reduction of aromatic nitro-groups. PMID- 4150139 TI - Studies on human placental carbon monoxide-binding cytochromes. PMID- 4150140 TI - The interactions of inducers, inhibitors, and substrates of drug-metabolizing enzymes with rat liver cytochrome P-450. PMID- 4150141 TI - Metabolism of carbidopa (1-(-)-alpha-hydrazino-3,4-dihydroxy-alpha methylhydrocinnamic acid monohydrate), an aromatic amino acid decarboxylase inhibitor, in the rat, rhesus monkey, and man. PMID- 4150142 TI - Medico-legal brief: physician liability for health care assistants. PMID- 4150143 TI - Drug-induced extrapyramidal syndromes. PMID- 4150144 TI - Neural cardiovascular control and hypertension. PMID- 4150145 TI - [Ulcerative colitis]. PMID- 4150146 TI - [Regional enteritis Crohn (author's transl)]. PMID- 4150147 TI - Studies on the activity of some enzymes in allergic bronchial asthma. PMID- 4150148 TI - Action of anticholinergic and related agents on single vestibular neurones. PMID- 4150150 TI - Drugs acting on the heart. PMID- 4150149 TI - Increase in adrenal monoamine oxidase activity in hypophysectomized rats after ACTH. PMID- 4150151 TI - Enzyme activities related to fatty acid synthesis in developing mammalian lung. PMID- 4150152 TI - The phenylalanine hydroxylating system from mammalian liver. PMID- 4150153 TI - The biotin-dependent enzymes. PMID- 4150154 TI - A laboratory comparison of Copper Kettle, Fluotec Mark 2, and Pentec vaporizers. PMID- 4150156 TI - Behavior and electrical activity in the hydrozoan Proboscidactyla flavicirrata (Brandt). I. The hydroid colony. PMID- 4150157 TI - Photoperiodic control of development in Chaoborus americanus with special reference to photoperiodic action spectra. PMID- 4150155 TI - [A phosphorylated biguanide: benfosformin (JAV 852). II. General pharmacological properties]. PMID- 4150158 TI - The effect of fluphenazine in psychologically normal volunteers: some temporal, performance, and biochemical relationships. PMID- 4150159 TI - [The index of dental caries in school children from the Perly village in the Province of Olsztyn]. PMID- 4150160 TI - [Use of bone grafts]. PMID- 4150161 TI - [Combined use of gangliolytics and ethyron for blood circulation control during surgical trauma]. PMID- 4150162 TI - Investigation of heterotopically transplanted dog hearts after preservation. PMID- 4150163 TI - Use of chemotherapy as anti-suicidal prophylaxis. PMID- 4150164 TI - Mitigation of secondary disease of allogeneic mouse radiation chimeras by modification of the intestinal microflora. PMID- 4150165 TI - Emergency care of acute poisonings. PMID- 4150167 TI - [Federation conference renew board members and council of delegates]. PMID- 4150166 TI - [The incidence of acute and chronic hepatitis among members of medical professions (author's transl)]. PMID- 4150168 TI - [The mineral composition of food rations for testers of the biological life support system]. PMID- 4150170 TI - Effect of human chorionic gonadotrophin on plasma and urine testosterone in boys with delayed puberty. PMID- 4150171 TI - Plasma and urine testosterone responses to human chorionic gonadotrophin (HCG) in children with delayed puberty. PMID- 4150172 TI - Pacemaker-induced hypotension for intracranial aneurysm surgery. PMID- 4150173 TI - Nurse practitioner, family practice nurse or physician's assistant. PMID- 4150174 TI - Isolated beta-adrenergic binding sites: a potential assay vehicle for catecholamines. PMID- 4150175 TI - [5 years' experience with prolonged-action neuroleptics]. PMID- 4150176 TI - An in vitro and pharmacological comparison of amoxicillin and ampicillin. PMID- 4150177 TI - Hypergastrinemia in familial multiple endocrine adenomatosis. PMID- 4150178 TI - Mode of action of a staphylococcal anti-inflammatory factor. PMID- 4150179 TI - Localization of gamma-glutamyl transpeptidase in rabbit lens, ciliary process and cornea. PMID- 4150180 TI - Stand up and be counted. PMID- 4150181 TI - An unusual presacral tumor. PMID- 4150182 TI - Pancreatic transplantation for diabetes mellitus. PMID- 4150183 TI - Detection of breast cancer. A review of cancer registry from Blessing Hospital, Quincy. PMID- 4150184 TI - Clinical conference: bronchogenic cyst. PMID- 4150185 TI - An ambulance strategy for Illinois. PMID- 4150186 TI - "Where have all the doctors gone"? PMID- 4150187 TI - Are you satisfied with your CME? PMID- 4150188 TI - The hospital practice of medicine. PMID- 4150189 TI - The viewbox. PMID- 4150191 TI - Editorials: Against medical advice. PMID- 4150190 TI - Editorial: Opportunistic infection. PMID- 4150192 TI - EKG of the month. PMID- 4150194 TI - Surgical grand rounds: intussusception in an adult. PMID- 4150195 TI - The anesthesiologist and the intensive care unit. PMID- 4150193 TI - MEDICHEK--the Illinois program of early periodic screening, diagnosis and treatment--what is it? PMID- 4150196 TI - Anesthesiologist-surgeon relationships. PMID- 4150197 TI - Anesthesiologist-hospital relationships. PMID- 4150199 TI - Otitis externa. PMID- 4150200 TI - External otitis: otological problems. PMID- 4150198 TI - Effect of B-cell mitogens on lymphocyte subpopulations possesing C'3 and Fc receptors. AB - By the use of a rosette method allowing the detection at the cellular level of lymphocytes simultaneously binding Fc- and C'3-sensitized red cells it was found that about 70% of the rosette-forming cells from spleens of nude and normal mice possessed receptors for both Fc and C'3, whereas 30% only had Fc receptors. Very few, if any, lymphocytes possessed only C'3 receptors. The B-cell mitogens, purified-protein derivative of tuberculin (PPD), lipopolysaccharide from Escherichia coli (LPS), and pneumococcal polysaccharide type SIII (SIII), induced marked changes of these receptor-bearing lymphocytes. PPD caused a rapid loss of cells capable of binding C'3 and a concomitant increase of only Fc-binding cells, which was detected after only 24 h. LPS and SIII induced analogous changes, but they were not detected until 48 h and were not complete until after 72 h. It is suggested that immature lymphocytes possess both Fc and C'3 receptors and lose the latter receptor upon differentiation induced by B-cell mitogens PPD. and LPS would affect different populations of B cells, PPD-activating cells that have already reached a higher differentiation stage, whereas LPS and SIII would activate more immature B cells. PMID- 4150201 TI - Electrophysiologic effects of dopamine on sheep cardiac Purkinje fibers. PMID- 4150202 TI - [Local and general body injuries due to incorporated metals and plastics]. PMID- 4150203 TI - [Therapy and prognosis of medial femur neck fractures]. PMID- 4150204 TI - [Accidents and retinal detachment]. PMID- 4150205 TI - [Injuries due to lightning flashes]. PMID- 4150206 TI - [Case report of health insurance practice. Concealment of previous disease in vocational disability additional insurance]. PMID- 4150207 TI - [Health risks in aviation]. PMID- 4150208 TI - Phenylalanine to tyrosine ratio in renal failure. PMID- 4150209 TI - Clinical aspects of the anti-arrhythmic actions of beta-receptor blocking drugs. 2. Clinical pharmacology. PMID- 4150210 TI - [Periarteritis nodosa, developing after vaccination]. PMID- 4150211 TI - Morphology of deep and superficial venous thrombosis and of thrombosis due to panphlebitis. PMID- 4150212 TI - [Effects of vaso-active drugs on the full-thickness skin autograft 1. Effect on plasma inhibition]. PMID- 4150213 TI - A kinetic study of the effects of sympatholytic agents on the responses to field stimulation in guinea-pig atrium. PMID- 4150214 TI - Some pharmacological characteristics of ganglionic activity of lobeline. PMID- 4150215 TI - [Pharmacokinetics and metabolism of fominoben (Noleptan) in man]. PMID- 4150216 TI - [Report on a preliminary open clinical study of mianserin (GB 94), a tetracyclic antidepressant]. PMID- 4150217 TI - Three generations of selection for high and low donor competences of splenomegaly in chickens. PMID- 4150218 TI - Interference in the Zimmerman test for steroids. PMID- 4150222 TI - The effect of anaemia on ion exchange in the southern flounder (Paralichthys lethostigma). PMID- 4150220 TI - Potentiometric evidence for the active transport of sodium and chloride across excised gills of Callinectes sapidus. PMID- 4150224 TI - Temperature regulation of the little brown bat, Myotis lucifugus after acclimation at various ambient temperatures. PMID- 4150225 TI - Responses to low oxygen conditions in two species of the mud snail Nassarius. PMID- 4150227 TI - Some physiological responses to anoxia in the great plains toad, Bufo cognatus. PMID- 4150229 TI - Absolute duration of survival of Tammar wallaby (Macropus eugenii, Marsupialia) on sea water and dry food. PMID- 4150230 TI - Osmoregulation in the pink shrimp Penaeus duorarum Burkenroad. PMID- 4150231 TI - Temperature-dependent shifts in the metabolism of a cool temperate reptile, Thamnophis sirtalis parietalis. PMID- 4150232 TI - Regulation of the ventilation-perfusion ratio in the gills of Dasyatis sabina and Squalus suckleyi. PMID- 4150234 TI - The chromatic physiology of the catfish Ictalurus melas (Rafinesque). I. The melanophore responses of intact and eyeless fish. PMID- 4150236 TI - Energy utilization and water requirements of captive Myotis thysanodes and Myotis lucifugus (Chiroptera). PMID- 4150239 TI - ODA lay conference on prevention of dental disease. PMID- 4150238 TI - Hormonal regulation of rat liver cells cultured in chemically defined medium. Dexamethasone and insulin effects on different forms of tyrosine 2-oxoglutarate transaminase. PMID- 4150240 TI - [Pharmacological studies on the new indene derivatives with beta-adrenergic blocking activity (author's transl)]. PMID- 4150241 TI - [Ecological analysis of arbovirus transmission cycles (a review of the literature)]. PMID- 4150242 TI - [Clinical application of beta-blockaders]. PMID- 4150244 TI - Accelerated medical graduates studied. PMID- 4150243 TI - [Treatment of phantom limb syndrome in patients after amputation of the extremities]. PMID- 4150245 TI - The relationship of the metabolism of anticancer agents to their activity. PMID- 4150246 TI - Role of alpha-adrenoceptors in prostaglandin E mediated negative feedback control of the secretion of noradrenaline from the sympathetic nerves of isolated guinea pig vas deferens. PMID- 4150247 TI - Microassay of tyrosine-amino transferase and p-hydroxyphenylpyruvic acid oxidase in mammalian liver and patients with hereditary tyrosinemia. PMID- 4150248 TI - Drugs for angina pectoris. PMID- 4150249 TI - A durohydroquinone oxidation site in the mitochondrial transport chain. PMID- 4150250 TI - Biogenesis of mitochondria. 20. The effects of altered membrane lipid composition on mitochondrial oxidative phosphorylation in Saccharomyces cerevisiae. PMID- 4150251 TI - Contribution of inhibition of NADH-dehydrogenase to the cardiotoxic effects of halothane. PMID- 4150252 TI - The ICU and collegiate nursing education. PMID- 4150253 TI - Guided reading: a strategy to enhance learning. PMID- 4150254 TI - Change processes should involve baccalaureate nursing students. PMID- 4150255 TI - Research for the undergraduate student in nursing. PMID- 4150256 TI - Evaluation of faculty and students--a means towards fuller communication and greater productivity. PMID- 4150257 TI - Teaching organizational concepts to nurses in community mental health. PMID- 4150258 TI - [Pubertal development of boys following surgical correction of cryptorchism]. PMID- 4150259 TI - The role of taste in disease and drug therapy and certain drug-nutrient interactions. PMID- 4150260 TI - [Treatment of myocardial ischemia: review]. PMID- 4150261 TI - [Therapeutic significance of the beta-receptor blockade in lithium-induced tremor. Therapeutic trials with Pindolol and Practolol]. PMID- 4150262 TI - [Occupational lung diseases]. PMID- 4150263 TI - Harkavy's syndrome. PMID- 4150264 TI - Prostaglandin-like activity of various fractions of ram semen: their role in the immune rejection of the nematode Nippostrongylus brasiliensis from the small intestine of rats. PMID- 4150265 TI - [The neuron and memory]. PMID- 4150266 TI - [Menacing tachycardial arrhythmias]. PMID- 4150267 TI - Posthepatitic severe aplastic anemia--an indication for early bone marrow transplantation. PMID- 4150268 TI - Histamine H2-receptors in the sheep bronchus and cat trachea: the action of burimamide. AB - Histamine-induced relaxation of the sheep bronchus was antagonized by burimamide but not by mepyramine, indicating the presence of H(2)-receptors. Mepyramine or burimamide alone produced partial antagonism of histamine-induced relaxation of the cat trachea. Both inhibitors added simultaneously effectively abolished the histamine response, suggesting that both H(1)- and H(2)-receptors are active in relaxing the cat trachea. PMID- 4150269 TI - Effect of alpha-blocking drugs in asthma. PMID- 4150270 TI - Clinical and pharmacokinetic studies of minoxidil, a new antihypertensive agent. PMID- 4150271 TI - Blood pressure over-shoot due to acute clonidine (Catapres) withdrawal: studies on arterial and urinary catecholamines and suggestions for management of the crisis. PMID- 4150272 TI - Plasma renin and angiotensin levels in human hypertension following treatment. PMID- 4150274 TI - [Toxic effect of the working environment on oral mucosa in workers at the Zabrze coke plant]. PMID- 4150273 TI - A new look at the treatment of severe hypertension. PMID- 4150275 TI - Comparison of the in vitro deiodination of 125-I-, 127-I-, and 131-I diiodotyrosine by thyroid and liver homogenates and slices from rat and pig. PMID- 4150276 TI - Use of photoreceptor membrane suspensions for the study of rhodopsin and associated enzyme activities. PMID- 4150277 TI - On the rhodopsin cycle. PMID- 4150278 TI - Selenium in relation to dental caries. PMID- 4150279 TI - Treatment of external diseases with immunological properties. PMID- 4150280 TI - Electron transport system in human leukocyte mitochondria. PMID- 4150281 TI - Mannoheptulose and fatty acid synthesis in the rat. PMID- 4150282 TI - Letter: Substrate specificity of monoamine oxidase activity in various mouse and rat tissues. PMID- 4150283 TI - Letter: Stimulation of locomotor activity following injection of dopamine into the nucleus accumbens. PMID- 4150284 TI - Letter: Antagonism of central dipsogenic and peripheral vasoconstrictor reponses to angiotensin II with Sar Ala8 angiotensin II in the conscious cat. PMID- 4150285 TI - Letter: Effect of pH on the release of noradrenaline from micropipettes. PMID- 4150286 TI - Letter: Methadone N-oxide in the urine of methadone maintenance subjects--an artifact? PMID- 4150287 TI - Letter: Post-synaptic blockade of dopaminergic transmission by 6-hydroxydopamine. PMID- 4150288 TI - Letter: Biphasic responses to guanosyl nucleotides in two smooth muscle preparations. PMID- 4150289 TI - Letter: Similarity between the effects of dimethyl and monomethyl tricyclic drugs on reserpine effects in the frog and 5-hydroxytryptamine uptake by human blood platelets. PMID- 4150290 TI - Letter: A new chemotherapeutic property of metronidazole: effect against oxyurids in mice. PMID- 4150291 TI - Letter: Release of (3H)noradrenaline and (3H)metaraminol from rabbit pulmonary artery in vitro. PMID- 4150292 TI - Letter: Myocardial depressant action of ethyl acetate. PMID- 4150293 TI - Letter: A simple screening test for drugs of potential use in ethanol withdrawal. PMID- 4150294 TI - Letter: Brain adenyl cyclase in methadone treatment of morphine dependency. PMID- 4150295 TI - The pharmacology of azidomorphine and azidocodeine. PMID- 4150296 TI - Studies on the nature of the increased monoamine oxidase activity in the rat heart after adrenalectomy. PMID- 4150297 TI - The distribution of delta1-tetrahydrocannabinol and 7-hydroxy-delta tetrahydrocannabinol in the mouse brain after intraventricular injection. PMID- 4150298 TI - Chemical composition and potential activity of Argentine marihuana. PMID- 4150299 TI - Kinetics of three structurally related bicyclic antidepressant compounds--a comparison in the dog. PMID- 4150300 TI - The binding of paracetamol to plasma proteins of man and pig. PMID- 4150301 TI - Dissolution and bioavailability of digoxin tablets. PMID- 4150302 TI - An analogue computer study of the dialysis of salicylic acid from micellar solutions of polysorbate 20 and 80. PMID- 4150303 TI - Determination of the thermodynamics of hydroxyl and carboxyl groups in solutions of drug molecules. PMID- 4150304 TI - A note on the chemical change of pentazocine in aqueous acidic media. PMID- 4150305 TI - Letter: Salbutamol and inhibition of uterine contractions. PMID- 4150306 TI - Letter: The influence of substrates and buffer solutions on the estimation of monoamine oxidase activity. PMID- 4150307 TI - Letter: Securinine. PMID- 4150308 TI - An alternative staffing proposal for emergency rooms. Three-year experience in a rural hospital. PMID- 4150309 TI - [Use of propranolol in acute intermittent porphyria]. PMID- 4150310 TI - Secretory characteristics of pancreatic gamma-glutamyl transpeptidase. PMID- 4150311 TI - A method for measuring mental performance in the elderly and its use in a pilot clinical trial of meclofenoxate in organic dementia (preliminary communication). PMID- 4150312 TI - A study of the antiarrhythmic action of certain beta-blocking agents. PMID- 4150313 TI - [The 50th anniversary of the Ist All-Russian Congress of Pathologists]. PMID- 4150314 TI - Editorial: Turner's and Noonan's syndromes. PMID- 4150315 TI - Monitoring depth of anesthesia. PMID- 4150316 TI - A correlational study of the community adaptation schedule and the Minnesota Multiphasic Personality Inventory. PMID- 4150317 TI - Studies on prolactin inhibition of thyroxine-induced metamorphosis in Rana catesbeiana tadpoles. PMID- 4150318 TI - Interview: Russell B. Roth, M.D., president of the American Medical Association. PMID- 4150319 TI - Cannabis-induced psychosis. PMID- 4150320 TI - Post-mortem findings in East African birds of prey. PMID- 4150321 TI - Relationship between plasma antipyrine half-lives and hepatic microsomal drug metabolism in dogs. PMID- 4150322 TI - Azaperone and the hepatic microsomes: effects on cytochrome P-450 concentration and on NADPH-cytochrome c-reductase activity. PMID- 4150323 TI - Cyclic GMP. PMID- 4150324 TI - Metiamide--an orally active histamine H2-receptor antagonist. PMID- 4150325 TI - Studies on the mode of action of histamine H1- and H2-receptor antagonists on gastric histamine methyltransferase. PMID- 4150326 TI - Augmentation of pentagastrin stimulated gastric secretion in the Heidenhain pouch dog by amodiaquine: inhibition of histamine methyltransferase in vivo? PMID- 4150327 TI - Effect of burimamide on gastric acid secretion and gastric mucosal blood flow in cats. PMID- 4150328 TI - Similar actions of methylated histamines and histamine receptor antagonists on gastric histamine methyltransferase. PMID- 4150329 TI - Pharmacological studies on the role of histamine in thermoregulation. PMID- 4150330 TI - Immunserum to a protein which reduces the biological activity of histamine. PMID- 4150331 TI - The influence of imidazole and some of its derivatives on isolated guinea-pig's heart auricles. PMID- 4150332 TI - The influence of burimamide on 14C-histamine uptake and metabolism by guinea pig atrium and mouse neoplastic mast cells, in vitro. PMID- 4150333 TI - Modifications of brain HA metabolism induced by antihistamines. PMID- 4150334 TI - Effect of burimamide on histamine metabolism. PMID- 4150335 TI - Electroencephalographic, behavioural and visceral effects of intraventricular infusion of histamine in the rabbit. PMID- 4150336 TI - Cardiovascular effects of a newer antiarrhythmic agent, disopyramide phosphate. PMID- 4150337 TI - Low tension glaucoma. PMID- 4150338 TI - Glutamine synthetase of pea leaves. I. Purification, stabilization, and pH optima. PMID- 4150339 TI - Studies on the assay and activities of guanyl and adenyl cyclase of rat liver. PMID- 4150340 TI - Purification and some properties of a protein factor required for light-dependent transhydrogenase in Rhodopseudomonas spheroides. PMID- 4150341 TI - Control of cytochrome P-450 in rat testis mitochondria by human chorionic gonadotrophin. PMID- 4150342 TI - Isocitrate dehydrogenase from Rhodopseudomonas spheroides: kinetic mechanism and further characterization. PMID- 4150343 TI - Change of activity and substrate specificity of human glucose 6-phosphate dehydrogenase by oxidation. PMID- 4150344 TI - The airways response to phenylephrine after blockade of alpha and beta receptors in extrinsic bronchial asthma. PMID- 4150345 TI - Therapeutic implications of the drug lag. PMID- 4150346 TI - [Studies of caries in brain damaged children]. PMID- 4150347 TI - [Proliferative potential of hematopoietic cells serially transplanted into lethally irradiated animals]. PMID- 4150348 TI - Management of congenital defects of the anterior abdominal wall. PMID- 4150349 TI - Ulcerative colitis. Selected clinical, diagnostic and therapeutic aspects. II. PMID- 4150350 TI - Studies on the function of cell membrane. 6th report. Influence of sex hormones on the elevation of NADH-cytochrome c reductase activity in liver plasma membrane of CCl4-administered rats. PMID- 4150351 TI - Studies on the function of cell membrane. 7th report. Influence of CCl4 administration of solubilization of the enzymes in electron transport system in rat liver plasma membrane and microsome. PMID- 4150352 TI - Studies on monoamine oxidase. Report 22. Effects of NaNO2 and NH2OH on mitochondrial MAO in rat brain. PMID- 4150353 TI - Beta-adrenergic blocking action of ruthenium red. PMID- 4150354 TI - Multiple endocrine adenomatosis. PMID- 4150355 TI - [Caries epidemiology of Slovenians]. PMID- 4150356 TI - New isothiazole derivatives. 3. Influence on glucose consumption and lactic acid production in tissue cultures. PMID- 4150358 TI - Erythrocytic nicotinamide-adenine dinucleotide phosphate levels and the genetic regulation of erythrocytic glucose 6-phosphate dehydrogenase activity in the inbred mouse. PMID- 4150357 TI - Studies on bile secretion in man. I. Choleresis and composition of bile during basal secretion. PMID- 4150359 TI - Classification and properties of peripheral adrenergic receptors. PMID- 4150360 TI - Adrenergic drugs in the treatment of hypertension. PMID- 4150361 TI - [Methods, motivation, and mortality of 263 cases of attempted suicide observed at the Hospital Principal, Dakar, during a five year period]. PMID- 4150362 TI - [Diagnostic difficulties raised by a rounded post-traumatic thoracic image]. PMID- 4150363 TI - Pharmacologic control of premature labor. PMID- 4150364 TI - Enzyme induction in human fetal liver in organ culture. PMID- 4150365 TI - Studies of glutamate dehydrogenase. The binding of NADH and NADPH to beef-liver glutamate dehydrogenase. PMID- 4150367 TI - Histochemical and ultrastructural study of muscle biopsies in 3 cases of dystrophia myotonica in the newborn child. PMID- 4150366 TI - Pathology of 'pseudotumours' of the orbit: a review. PMID- 4150368 TI - Destruction of low efficiency markers is a slow process occurring at a heteroduplex stage of transformation. PMID- 4150369 TI - Intracellular competition for a mismatch recogition system and marker-specific rescue of transforming DNA from inactivation by ultraviolet irradiation. PMID- 4150370 TI - Malnutrition and oral health of children. PMID- 4150371 TI - [Adrenergic receptors in the digestive tract]. PMID- 4150372 TI - Epsilon-adenylylated glutamine synthetase: an internal fluorescence probe for enzyme conformation. AB - A fluorescent derivative of ATP, epsilon-ATP, was used to adenylylate glutamine synthetase (EC 6.3.1.2) from Escherichia coli enzymatically. The epsilon adenylylated enzyme exhibits similar catalytic properties and inhibitor susceptibility to those of the naturally adenylylated enzyme. The fluorescence properties of the epsilon-adenosine and of tryptophan residues of the enzyme were used to study ligand-induced conformational changes involving alterations of the tryptophan regions and the adenylylation site of the protein. Binding of Mn(2+) to the epsilon-adenylylated enzyme is accompanied by a decrease of epsilon adenosine fluorescence as compared to the effect observed for the Mg(2+) binding. An ADP binding study shows that at low ADP concentration, ADP causes enhancement of the tryptophan fluorescence only, reflecting the binding to unadenylylated subunits; and at high ADP concentration, ADP causes not only enhancement of the fluorescence, but also a quenching of the fluorescence of enzyme-bound epsilon AMP, reflecting binding to the adenylylated subunits. Dissociation constants calculated from these fluorescence changes agree well with those determined from binding studies of ADP to adenylylated and unadenylylated enzymes. Binding of the feedback inhibitor, alanine, to Mn(2+)-dependent glutamine synthetase causes enhancement of the epsilon-AMP fluorescence, from which a dissociation constant of 1.5 mM was calculated for the inhibitor. The fluorescence changes observed due to ligands binding suggest that Mg(2+) and Mn(2+) stabilize different conformational states of the enzyme. PMID- 4150373 TI - [Current antihypertensive drugs: mechanism of action]. PMID- 4150374 TI - Differences in Australia antigen carrier rates in northern Nigeria. PMID- 4150375 TI - Oral theophylline preparations--a review of their clinical efficacy in the treatment of bronchial asthma. PMID- 4150376 TI - Biting insect survey: a statistical report. PMID- 4150377 TI - Acute myocardial infarction and muscle salvage: a potential role for pharmacological agents. PMID- 4150378 TI - The nature of treatment selection in coronary artery disease. Experience with medical and surgical treatment of a chronic disease. PMID- 4150379 TI - [Spontaneous resorption of teeth (author's personal cases)]. PMID- 4150380 TI - Studies on chromatin-associated protein phosphokinase of submandibular gland from isoproterenol-treated rats. PMID- 4150382 TI - The physician's assistant in GEorgia. PMID- 4150381 TI - Activity of some hydrolases in animals with transplanted and spontaneous tumours. PMID- 4150383 TI - Polysaccharides of the genus Bacillus cross-reactive with the capsular polysaccharides of Diplococcus pneumoniae type 3, Haemophilus influenzae type b, and Neisseria meningitidis group A. AB - We studied 174 strains of the genus Bacillus for cross-reacting antigens to the capsular polysaccharides of groups A and C meningococcus, types I and III pneumococcus, and Haemophilus influenzae type b. Cross-reactions were detected by immunodiffusion in agarose gel by using type-specific antisera and confirmed by absorption and inhibition experiments. Of 20 Bacillus pumilis strains, six had an antigen cross-reacting with group A meningococcal polysaccharide. Other cross reactions included one strain of B. pumilis with H. influenzae type b, one of B. cereus var. mycoides with pneumococcus type III, and one of B. alvei with both type b and SIII polysaccharides. These cross-reacting antigens are polysaccharides of vegetative cells and may be extracellular in location. Because these bacilli have antigens cross-reacting with the virulence factors of pyogenic bacteria, they may, as normal flora, be an antigenic stimulus for "natural" serum anti-capsular antibodies to the type b Haemophilus and group A meningococcus polysaccharides. PMID- 4150384 TI - Filamentous capsulated streptococci from the human respiratory tract. I. Antigenic attributes of provisional capsular type 83 and its relationship to streptococci of so-called group M. AB - Two immunologically reactive polysaccharides have been isolated from the cell walls and from culture filtrates of a filamentous alpha-hemolytic streptococcus provisionally designated capsular type 83. Both polysaccharides were purified by diethylaminoethyl-cellulose chromatography. Analysis indicates that the capsular polysaccharide consists of galactose and phosphorus, whereas the cell wall polysaccharide contains galactosamine, glucosamine, glucose, and phosphorus. On the basis of immunochemical experiments, it is suggested that the capsular polysaccharide is composed of galactose-phosphate units with terminal galactose residues at the nonreducing end. It has also been found that the capsular antigen of streptococcus type 83 is shared by a number of streptococcal strains classified in Lancefield's group M. The cell wall polysaccharide of streptococcus type 83 cross-reacts with antibody to the C(s), or cell wall-like capsular, polysaccharide of Diplococcus pneumoniae, and this cross-reactivity may be a reflection that the streptococcal antigen possesses certain structural features which are similar to those of pneumococcal C and C(s) polysaccharides. PMID- 4150385 TI - Filamentous capsulated streptococci from the human respiratory tract. II. Antigenic structure of provisional capsular types 89 and 83-89. AB - Two immunologically distinct polysaccharides have been isolated from the filamentous alpha-hemolytic streptococcus of provisional capsular type 89, recovered from the human respiratory tract. Chemical analyses indicate that the capsular polysaccharide consists of glucose, galactose, and a small amount of rhamnose, whereas the cell wall-associated polymer contains galactosamine, glucosamine, glucose, and phosphorus. Immunological studies suggest that the capsular polysaccharide is type specific and that the cell wall-associated carbohydrate, which cross-reacts with the C(8), or cell wall-like capsular polysaccharide of pneumococcus, may be group specific. A noncapsulated variant of the prototypic streptococcus of provisional type 89 was shown to possess the same cell wall-associated carbohydrate as the strain from which it was derived, but it proved to be poorly antigenic in rabbits. A filamentous capsulated streptococcus reacting with antisera to filamentous streptococci of both provisional capsular types 83 and 89 has been found to produce two capsular polysaccharides, each of which reacts with antibody to one of the aforementioned unitypic strains and represents an unusual binary capsulated streptococcus. PMID- 4150386 TI - Filamentous capsulated streptococci from the human respiratory tract. 3. Immunochemical studies of the cross-reactivity between the cell wall antigens of a filamentous streptococcus and of pneumococcus. AB - A cell wall-associated polysaccharide has been isolated from a noncapsulated mutant, 89R50, of the alpha-hemolytic filamentous streptococcus of provisional capsular type 89. Chemical analysis of the polysaccharide indicates that it consists of galactosamine, glucosamine, glucose, and phosphorus. Immunological cross-reactivity was observed between the streptococcal cell wall antigen and antibody to the cell wall-like capsular polysaccharide of pneumococcus. This cross-reactivity appears attributable to similarities in the teichoic acid moieties rather than in the mucopeptide moieties of the two polymers. No chemical or immunological differences were observed in the cell wall carbohydrate of the noncapsulated streptococcus, 89R50, and that of its capsulated progenitor. It is suggested that antibody to this cell wall polysaccharide might serve as a basis for grouping other filamentous strains of streptococci of diverse capsular types, the cell wall antigens of which show similar cross-reactivity with that of pneumococcus. PMID- 4150387 TI - Effects of neuroleptanesthesia on catecholamines. PMID- 4150388 TI - Prostaglandin metabolism. I. Cytoplasmic reduced nicotinamide adenine dinucleotide phosphate-dependent and microsomal reduced nicotinamide adenine dinucleotide-dependent prostaglandin E 9-ketoreductase activities in monkey and pigeon tissues. PMID- 4150389 TI - Isolation and characterization of the multiple forms of dihydrofolate reductase from methotrexate-resistant hamster cells. PMID- 4150390 TI - Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. 3. The Escherichia coli hemoflavoprotein: catalytic parameters and the sequence of electron flow. PMID- 4150391 TI - Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. IV. The Escherichia coli hemoflavoprotein: subunit structure and dissociation into hemoprotein and flavoprotein components. PMID- 4150392 TI - Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. V. Studies with the Escherichia coli hemoflavoprotein depleted of flavin mononucleotide: distinct roles for the flavin adenine dinucleotide and flavin mononucleotide prosthetic groups in catalysis. PMID- 4150393 TI - Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. VI. The reaction of carbon monoxide with the Escherichia coli holoenzyme, the hemoprotein, and free siroheme. PMID- 4150394 TI - Regional action to strengthen continuing education in nursing. Commentary on Southern Regional Education Board Council on Collegiate Education for Nursing 20th meeting, October 31 - November 2, 1973, Atlanta, Georgia. PMID- 4150395 TI - Dental materials which can be used to reduce caries in fissures. PMID- 4150396 TI - The effect on caries increments in dental students of topically applied acidulated phosphate fluoride (APF). PMID- 4150397 TI - Diagnosis of bacterial diseases by detection of serum antigens by counterimmunoelectrophoresis, sensitivity, and specificity of detecting Pseudomonas and pneumococcal antigens. PMID- 4150398 TI - Choice of antihistamines. PMID- 4150399 TI - Glutathione peroxidase activity as a function of dietary selenomethionine. PMID- 4150400 TI - Life and medical care in China today. PMID- 4150401 TI - Necrotizing myelitis: a clinico-pathologic report of two cases associated with diplococcus pneumoniae and mycoplasma pneumoniae infections. PMID- 4150402 TI - Histamine and 5-hydroxytryptamine uptake by some mucopolysaccharides. PMID- 4150403 TI - The pharmacology of slow reacting substance C and of arachidonic acid. PMID- 4150404 TI - Pharmacologial analysis of the mediators involved in the acute pulmonary edema produced in rats by adrenaline. PMID- 4150405 TI - [Effect of the flavonoid Na-(+)-epicatechine-2-sulfonate on circulation at rest and in stress]. PMID- 4150406 TI - [Pharmacological and toxicological characterization of a multicomponent preparation in the treatment of circulatory disorders]. PMID- 4150407 TI - [Graft-versus-host reaction, allogen diseases, and lymphoma]. PMID- 4150408 TI - Reversal by L-DOPA of the suppression of locomotor activity induced by inhibition of tyrosine-hydroxylase and DA-beta-hydroxylase in mice. PMID- 4150409 TI - [Effect of protein-deficient diet on the graft versus host reaction in the rat]. PMID- 4150410 TI - [Action of various beta adrenolytic agents on the alpha blocking properties of yohimbine in the dog]. PMID- 4150411 TI - [Mechanism of glucose oxidation by a strain of Pseudomonas fluorescens (type R). I. Measure of glucose-dehydrogenase activity in intact cells]. PMID- 4150412 TI - [Orthosympathetic reactions of the rat to the occlusion of portal circulation]. PMID- 4150413 TI - [Drug-induced phospholipid storage disease]. PMID- 4150414 TI - Onset of synthesis of mitochondrial enzymes during mouse development. Synchronous activation of parenteral alleles at the gene locus for the M-form of NADP dependent malate dehydrogenase. PMID- 4150417 TI - Preparation of partially purified, lipid-depleted cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase from rat liver microsomes. PMID- 4150418 TI - On the role of glial cells in the mammalian nervous system. Uptake, excretion, and metabolism of putative neurotransmitters by cultured glial tumor cells. PMID- 4150420 TI - Electron paramagnetic resonance-detectable electron acceptors in beef heart mitochondria. Reduced diphosphopyridine nucleotide ubiquinone reductase segment of the electron transfer system. PMID- 4150419 TI - (Omega -2) hydroxylation of fatty acids by a soluble system from bacillus megaterium. PMID- 4150421 TI - Abnormal microsomal cytochromes and electron transport in Morris hepatomas. PMID- 4150423 TI - Oral health in preschool Swedish children. 1. Three-year-old children. PMID- 4150422 TI - Adrenergic and antiadrenergic drugs. PMID- 4150424 TI - Cytochrome P450 and steroid 21-hydroxylation in microsomes from beef adrenal cortex. PMID- 4150425 TI - [Observations on the ecology and social behavior in the coral-reef fish Dascyllus marginatus Rueppell (Pisces, Pomacentridae)]. PMID- 4150426 TI - Smoking and drug consumption in white, black, and oriental men and women. PMID- 4150427 TI - The heme protein P-450 in steroid hydroxylation. PMID- 4150428 TI - [Separation and purification of D lactate dehydrogenase and glucose-6-phosphatate dehydrogenase from Leuconostoc lactis. Study of several properties]. PMID- 4150429 TI - [Nuclear magnetic resonance study of Co2+-NAD(H) and Co2+-NADP(H) complexes]. PMID- 4150430 TI - [Congenital non spherocytic hemolytic anemia due to G-6PD deficiency: physiological and biochemical study of an unusual variant. Relationship to Benevento G-6PD]. PMID- 4150431 TI - [The action of phosphate nucleosides on oxidation of NADH in mitochondria of the Xenopus laevis ovary]. PMID- 4150432 TI - Adult population estimate of Toxorhynchites brevipalpis. AB - An estimate of the numbers of adults of the predacious mosquito Toxorhynchites brevipalpis was made in a 1-ha biotope in Dar es Salaam, Tanzania, where the population of its larval prey Aedes aegypti was high, by means of the mark release-recapture method. Two months after the end of the rainy season, the number of adults was estimated to be 3 500-about 6 times the number of adult A. aegypti in the biotope. PMID- 4150433 TI - Depression of erythrocyte delta-aminolaevulinic acid dehydratase activity in alcoholics. PMID- 4150434 TI - Interaction between hormones and cyclic AMP in regulating specific hepatic enzyme synthesis. PMID- 4150435 TI - A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphazalazine (Salazopyrin). AB - Sixty-four patients with proven ulcerative colitis who had been maintained on sulphasalazine as their sole form of treatment for a minimum period of one year were entered into a controlled trial of sulphasalazine versus dummy tablets for a period of six months. All the patients admitted were not only symptom-free but also showed no evidence of inflammation on sigmoidoscopy and rectal biopsy. A patient was judged to have relapsed when there was a recurrence of colitic symptoms accompanied by sigmoidoscopic and histological evidence of inflammation. The patients who received dummy tablets had more than four times the relapse rate of those receiving sulphasalazine. The results were similar in patients who had been on maintenance treatment with sulphasalazine for less than three years before entry into the trial and in those who had been on this treatment for more than three years. It is concluded that maintenance treatment of ulcerative colitis with sulphasalazine should be continued indefinitely unless contraindicated by side effects. PMID- 4150436 TI - Patients' acceptance of physician's assistants. PMID- 4150437 TI - [Immunological problems in extracorporeal circulation]. PMID- 4150438 TI - Do D-glucosamine and D-galactosamine form part of specific receptor sites for competence substance on cell wall of Pneumococcus? PMID- 4150439 TI - Behavioral changes and aggressivity evoked by drugs in mice. PMID- 4150440 TI - Action of imidazole on the cardiac inotropic, phosphorylase activating and cyclic AMP producing effects of norepinephrine and histamine. PMID- 4150442 TI - Temperature-induced phase changes in membrane lipids and their influence on metabolic regulation. PMID- 4150441 TI - The role of the colon in the metabolism of salicylazosulphapyridine. PMID- 4150443 TI - Cardiac output during ritodrine treatment in premature labor. PMID- 4150444 TI - Formation of dihydrotestosterone and other 5 alpha-reduced metabolites by isolated seminiferous tubules and suspension of interstitial cells in a human testis. PMID- 4150445 TI - In vitro metabolism of testosterone by whole human testis, isolated seminiferous tubules and interstitial tissue. PMID- 4150446 TI - The role of immunoglobulin in the interaction of pneumococci and the properdin pathway: evidence for its specificity and lack of requirement for the Fc portion of the molecule. PMID- 4150447 TI - Clonal nature of the immune response to phosphorylcholine. II. Idiotypic specificity and binding characteristics of anti-phosphorylcholine antibodies. PMID- 4150448 TI - Enzymes of carbohydrate metabolism in normal human sebaceous glands. PMID- 4150449 TI - Steroid pathways in sebaceous glands. PMID- 4150450 TI - Cutaneous lipogenesis. Major pathways of carbon flow and possible interrelationships between the epidermis and sebaceous glands. PMID- 4150452 TI - Symposium on atherosclerosis. PMID- 4150451 TI - Electrophysiological investigation of GABA-mediated inhibition at the hermit crab neuromuscular junction. AB - 1. The inhibitory neuromuscular junction of the abductor muscle of the large claw of the hermit crab (Eupagurus bernhardus) was investigated using electrophysiological intracellular techniques in order to elucidate further the relative contributions of the pre- and post-synaptic mechanisms of action of GABA and of neural inhibition.2. The electrical constants of the post-synaptic membrane, calculated using the equations for a ;short cable' model, were characteristic of a poorly developed electrical excitability; the specific membrane resistance was usually < 1000 Omega cm(2) and the specific membrane capacitance was > 40 muF/cm(2).3. Stimulation of the excitatory axon to the abductor muscle of the large claw at a frequency of 20 Hz evoked highly facilitating excitatory junction potentials (e.j.p.s); stimulation of the inhibitory axon (60-220 Hz) during the excitatory train elicited inhibition which was manifest as an attenuation of the e.j.p.s.4. The addition of gamma aminobutyric acid (GABA) to the bathing solution produced a dose-dependent reduction of e.j.p. amplitude and membrane resistance. The inhibitory effect of concentrations (5 x 10(-5) and 1 x 10(-4)M) which caused a 40-75% e.j.p. attenuation could largely be accounted for by a post-synaptic action on membrane conductance.5. Experiments with picrotoxin suggest that presynaptic inhibitory mechanisms have an important role in neurally evoked inhibition.6. Picrotoxin (1 5 x 10(-5)M) effectively blocked neural inhibition and the actions of GABA in this preparation, whereas bicuculline proved to be considerably less potent and therefore less useful as a physiological tool for studying GABA-mediated inhibition in crustacea. PMID- 4150454 TI - Effects of cytochalasin B on uptake and release of putative transmitters by synaptosomes and on brain actomyosin-like protein. PMID- 4150453 TI - Reaction mechanism of NAD(P)H-linked oxygenases. PMID- 4150455 TI - Prostaglandin E2 as stimulator of haemopoietic stem cell proliferation. PMID- 4150457 TI - [Systematic preschool-child dental care in a rural district]. PMID- 4150456 TI - Sulphur-methylene isosterism in the development of metiamide, a new histamine H2 receptor antagonist. PMID- 4150458 TI - Emergency nursing. PMID- 4150459 TI - Equinatoxin, a lethal protein from Actinia equina--I. Purification and characterization. PMID- 4150460 TI - Equinatoxin, a lethal protein from Actinia equina. II. Pathophysiological action. PMID- 4150461 TI - Isolation of arboviruses from mosquitoes, biting midges, sandflies and vertebrates collected in Queensland, 1969 and 1970. PMID- 4150462 TI - The epidemiology of cutaneous leishmaniasis in Ethiopia. PMID- 4150463 TI - Proceedings: Development of filaria in mosquitoes: ultrastructure and autoradiography. PMID- 4150464 TI - Proceedings: Effects of pharyngeal armature of mosquitoes on microfilariae of Brugia pahangi. PMID- 4150465 TI - Arbovirus studies in Nupeko forest, a possible natural focus of yellow fever virus in Nigeria. II. Entomological investigations and viruses isolated. PMID- 4150466 TI - Proceedings: Hydrolases of the sporogonic stage of Plasmodium berghei nigeriensis. PMID- 4150467 TI - Letter: Biting insects and hepatitis B virus. PMID- 4150468 TI - [Proceedings: Weightlessness in space stations orbiting the earth]. PMID- 4150469 TI - Circulatory actions of phentolamine before and after autonomic blockade. PMID- 4150470 TI - Characteristics and pharmacologic utility of an intraocular pressure (IOP) model in unanesthetized rabbits. PMID- 4150471 TI - Translocation of inducible tyrosine aminotransferase to the mitochondrial fraction. Facilitation by acute uremia and other conditions. PMID- 4150472 TI - Analysis of proteins undergoing axonal transport in nigro-striatal neurons in the rat. PMID- 4150473 TI - Permeability of mitochondria from rat brain and rat liver to GABA. PMID- 4150475 TI - [Case report and time of therapy in orchidopexia]. PMID- 4150474 TI - Effect of dibutyryl-cyclic AMP and dexamethasone on noradrenaline synthesis in isolated superior cervical ganglia. PMID- 4150476 TI - [Letter: Optimal time for surgery of maldescensus testis]. PMID- 4150477 TI - [Manifestation of juvenile diabetes mellitus following postvaccinal encephalomyelitis]. PMID- 4150478 TI - [Standard values of gamma glutamyl transpeptidase and serum alanine aminotransferase as well as aspartate aminotransferase using substrate-optimized tests]. PMID- 4150479 TI - Letter: Beta receptors and renin release. PMID- 4150480 TI - Letter: What are physician assistants, and what do they do? PMID- 4150481 TI - [Integrity of the organism and the neurohumoral interrelationships normally and in pathology]. PMID- 4150482 TI - [Study of dysregulatory visceropathies]. PMID- 4150483 TI - [Unique experiment with the prolonged stay of man under increased pressure]. PMID- 4150484 TI - [Electron microscopic study of the undescended testicles of children]. PMID- 4150485 TI - Drug abuse and the emergency room physician. PMID- 4150486 TI - Experimental immunity to a metabolite of halothane and fluroxene: cutaneous delayed-type hypersensitivity. PMID- 4150487 TI - The effect of ethionine on the energy-producing metabolism in the rat pancreas. II. Alterations of tissue levels of adenine nucleotides, pyridine nucleotides, and glycolytic metabolites. PMID- 4150488 TI - Analytical study of microsomes and isolated subcellular membranes from rat liver. I. Biochemical methods. AB - The series introduced by this paper reports the results of a detailed analysis of the microsomal fraction from rat liver by density gradient centrifugation. The biochemical methods used throughout this work for the determination of monoamine oxidase, NADH cytochrome c reductase, NADPH cytochrome c reductase, cytochrome oxidase, catalase, aminopyrine demethylase, cytochromes b(5) and P 450, glucuronyltransferase, galactosyltransferase, esterase, alkaline and acid phosphatases, 5'-nucleotidase, glucose 6-phosphatase, alkaline phosphodiesterase I, N-acetyl-beta-glucosaminidase, beta-glucuronidase, nucleoside diphosphatase, aldolase, fumarase, glutamine synthetase, protein, phospholipid, cholesterol, and RNA are described and justified when necessary. PMID- 4150489 TI - Analytical study of microsomes and isolated subcellular membranes from rat liver. II. Preparation and composition of the microsomal fraction. AB - Liver homogenates have been submitted to quantitative fractionation by differential centrifugation. Three particulate fractions: N (nuclear), ML (large granules), and P (microsomes), and a final supernate (S) have been obtained. The biochemical composition of the microsomal fraction has been established from the assay and distribution pattern of 25 enzymatic and chemical constituents. These included marker enzymes for mitochondria (cytochrome oxidase), lysosomes (acid phosphatase and N-acetyl-beta-glucosaminidase), and peroxisomes (catalase). The microsomal preparations were characterized by a moderate contamination with large cytoplasmic granules (only 6.2% of microsomal protein) and by a high yield in microsomal components. Enzymes such as glucose 6-phosphatase, nucleoside diphosphatase, esterase, glucuronyltransferase, NADPH cytochrome c reductase, aminopyrine demethylase, and galactosyltransferase were recovered in the microsomes to the extent of 70% or more. Another typical behavior was shown by 5' nucleotidase, alkaline phosphatase, alkaline phosphodiesterase I, and cholesterol, which exhibited a "nucleomicrosomal" distribution. Other complex distributions were obtained for several constituents recovered in significant amount in the microsomes and in the ML or in the S fraction. PMID- 4150491 TI - [Therapeutic possibilities of 3,4,5-trimethoxybenzoyl-epsilon-amino-caproic acid (C-3) in non-infarctual coronary pain syndrome]. PMID- 4150492 TI - Proceedings: International Union Against Cancer: brief history, organization, and program review of a non-governmental voluntary organization. PMID- 4150490 TI - Analytical study of microsomes and isolated subcellular membranes from rat liver. 3. Subfractionation of the microsomal fraction by isopycnic and differential centrifugation in density gradients. AB - Rat liver microsomal fractions have been equilibrated in various types of linear density gradients. 15 fractions were collected and assayed for 27 constituents. As a result of this analysis microsomal constituents have been classified, in the order of increasing median density, into four groups labeled a, b, c, and d. Group a includes: monoamine oxidase, galactosyltransferase, 5'-nucleotidase, alkaline phosphodiesterase I, alkaline phosphatase, and cholesterol; group b: NADH cytochrome c reductase, NADPH cytochrome c reductase, aminopyrine demethylase, cytochrome b(5), and cytochrome P 450; group c: glucose 6 phosphatase, nucleoside diphosphatase, esterase, beta-glucuronidase, and glucuronyltransferase; group d: RNA, membrane-bound ribosomes, and some enzymes probably adsorbed on ribosomes: fumarase, aldolase, and glutamine synthetase. Analysis of the microsomal fraction by differential centrifugation in density gradient has further dissociated group a into constituents which sediment more slowly (monoamine oxidase and galactosyltransferase) than those of groups b and c, and 5'-nucleotidase, alkaline phosphodiesterase I, alkaline phosphatase, and the bulk of cholesterol which sediment more rapidly (group a2). The microsomal monoamine oxidase is attributed, at least partially, to detached fragments of external mitochondrial membrane. Galactosyltransferase belongs to the Golgi complex. Group a2 constituents are related to plasma membranes. Constituents of groups b and c and RNA belong to microsomal vesicles derived from the endoplasmic reticulum. These latter exhibit a noticeable biochemical heterogeneity and represent at the most 80% of microsomal protein, the rest being accounted for by particles bearing the constituents of groups a and some contaminating mitochondria, lysosomes, and peroxisomes. Attention is called to the operational meaning of microsomal subfractions and to their cytological complexity. PMID- 4150494 TI - [Postmortem bacteriological findings in the trachea of tracheotomized and nontracheotomized subjects]. PMID- 4150493 TI - Proceedings: European Organization for Research on Treatment of Cancer: origin, organization, and current activities. PMID- 4150495 TI - [Prehospital treatment of patients with acute pancreatitis]. PMID- 4150496 TI - [Salvage operations in total and partial avulsions of the extremities]. PMID- 4150497 TI - Transplantation of the mouse heart--a useful research model. PMID- 4150498 TI - Treatment patterns in psychiatry: clinical and personality features of elderly hospitalized patients during milieu, single-drug and multiple-drug programs. PMID- 4150499 TI - Cellularity and lipogenic enzyme activities of porcine intramuscular adipose tissue. PMID- 4150500 TI - The training and use of physician's assistants in Indiana. PMID- 4150501 TI - An electron microprobe analysis of the resistant sporangium wall of Coelomomyces psorophorae. PMID- 4150502 TI - The influence of reducing the C7-C8 double bond of codeine to give dihydrocodeine on the relative physiological availability of the drugs in man. PMID- 4150503 TI - Proceedings: The influence of fines on the flow and compaction properties of lactose. PMID- 4150504 TI - Proceedings: The effects of granule porosity and strength on the porosity, air permeability and tensile strength of tablets. PMID- 4150505 TI - Proceedings: A friability test for granules. PMID- 4150506 TI - Proceedings: The effect of sintering on the pore structure and strength of plastic matrix tablets prepared from polyvinyl chloride. PMID- 4150507 TI - Proceedings: Members of Miltantha section of Papaver as a source of morphinane alkaloids. PMID- 4150508 TI - Proceedings: The alkaloidal vesicles of Papaver somniferum. PMID- 4150509 TI - Proceedings: Phosphomonoesterases in Papaver somniferum latex. PMID- 4150510 TI - Proceedings: The oxidation of tyrosine a precursor of morphine by polyphenolase in the 1000g organelles of Papaver somniferum. PMID- 4150511 TI - Proceedings: Alkaloids in the bark of Zanthoxylum clava-herculis. PMID- 4150512 TI - Proceedings: The natural occurrence of tropane alkaloid N-oxides. PMID- 4150513 TI - Proceedings: The role of molecular diffusion in the bulk stability of o-w hydrocarbon emulsions. PMID- 4150514 TI - Proceedings: An investigation of the properties of propranolol hydrochloride in aqueous solution. PMID- 4150515 TI - Proceedings: Some physical properties of promethazine in aqueous solution. PMID- 4150516 TI - Proceedings: The apparent molal volumes, Ov, of hexamethonium bromide (HexBr2) and decamethonium bromide (DecaBr2) at 25 degrees. PMID- 4150517 TI - Proceedings: Approaches to the formulation of a long-acting intramuscular injection. PMID- 4150518 TI - Proceedings: Application of Buslik's concept of homogeneity to pharmaceutical ointments. PMID- 4150519 TI - Proceedings: The effect of thermodynamic activity on the percutaneous absorption of methyl nicotinate from water glycerol mixtures. PMID- 4150520 TI - Proceedings: Comparative bioavailability of proprietary hydrophilic topical steroid preparations. PMID- 4150521 TI - Proceedings: The effects of amphetamine, 2-aminoindane and 2-aminotetralin on the concentrations of whole brain noradrenaline, dopamine, 5-hydroxytryptamine and 5 hydroxyindoleacetic acid in the mouse. PMID- 4150522 TI - Proceedings: An interaction between morphine and fenfluramine in mice. PMID- 4150523 TI - Proceedings: The neuromuscular blockade caused by fractions obtained by chromatography of commercial B. multicinctus venom. PMID- 4150524 TI - Proceedings: The effects of some bungarotoxins on skeletal muscle fibres in tissue culture. PMID- 4150525 TI - Proceedings: The effects of beta-type bungarotoxins on the responses of the chick biventer cervicis muscle to cholinoceptor agonists. PMID- 4150526 TI - Proceedings: The effect of dopamine-antagonists and amantadine on the acquisition of the conditioned avoidance response in rats. PMID- 4150527 TI - Proceedings: The effect of phase-shift on the passive avoidance response in rats, and the modifying effect of chlordiazepoxide. PMID- 4150528 TI - The effect of sintering on the pore structure and strength of plastic matrix tablets. PMID- 4150529 TI - Proceedings: Inactivation by gamma-rays of Bacillus megaterium spores suspended in aqueous solutions of ethanol, acetone and 1,4-dioxane of widely varying concentrations. PMID- 4150530 TI - Proceedings: The effect of sporulation temperature upon the post-germinative resistance of Bacillus subtilis. PMID- 4150531 TI - Proceedings: Inhibitors of thymidylate synthetase as R factor curing agents. PMID- 4150532 TI - Proceedings: A comparison of the effect of polymyxin B sulphate and phenylethanol on Pseudomonas aeruginosa. PMID- 4150533 TI - Proceedings: Effect of additives on freeze-drying of a herpes virus. PMID- 4150534 TI - Proceedings: Rabbit eye irritation from bactericides in soft lens soaking solutions. PMID- 4150535 TI - Proceedings: Accelerated stability testing of freeze-dried preparations of Penicillium chrysogenum WIS54-1255. PMID- 4150536 TI - Proceedings: Correlation of androgenic activities of the lower testosterone esters in rat, with Rm values and hydrolysis rates. PMID- 4150537 TI - Proceedings: Dissolution rate as a parameter in structure-activity studies. PMID- 4150538 TI - Proceedings: The influence of non-ionic surfactant type on the transport of a drug across a biological membrane. PMID- 4150539 TI - Proceedings: Transit in free films: surface heterogeneity. PMID- 4150540 TI - Proceedings: Some pharmacological indications of a role for taurine in the regulation of pituitary activity. PMID- 4150541 TI - Proceedings: Studies on the central hypotensive effects of clonidine. PMID- 4150542 TI - Proceedings: Absorption, distribution and excretion of doxapram hydrochloride in the rat. PMID- 4150543 TI - Proceedings: The absorption, distribution, and excretion of 2-amino-4 phenylsulphonyl benzene sulphonamide (NSD 3004) in rats. PMID- 4150544 TI - Proceedings: Interaction of phenobarbitone and ethanol studied from dose-response curves and drug concentrations in blood. PMID- 4150545 TI - Proceedings: Uncaria species as sources of the alkaloids gambirine and the roxburghines. PMID- 4150546 TI - Proceedings: The interconversion of open and closed E ring oxindole alkaloids in Mitragyna species. PMID- 4150547 TI - Proceedings: Environment and the production of cannabinoids in Cannabis sativa. PMID- 4150548 TI - Proceedings: Sapogenins and phytosterols of some Digitalis species. PMID- 4150549 TI - Proceedings: A screening procedure for Euphorbia co-carcinogenic irritants. PMID- 4150550 TI - Proceedings: An evaluation of tolu balsam by gas-liquid chromatography. PMID- 4150551 TI - Proceedings: Dissolution rate and the surface area of compacted powder systems. PMID- 4150552 TI - Proceedings: The influence of micelle-drug solubilization on dissolution rates. PMID- 4150553 TI - Proceedings: The effect of solvent flow on the dissolution rate of a non disintegrating solid (potassium chloride). PMID- 4150554 TI - Proceedings: The effect of surface coatings on the dissolution rate of a non disintegrating solid (potassium chloride). PMID- 4150555 TI - Proceedings: Bioavailability of salicylamide from tablets. PMID- 4150556 TI - Proceedings: A solid dosage form with constant release. PMID- 4150557 TI - Proceedings: The effect of formulation on the availability of sulphadiazine. PMID- 4150558 TI - Proceedings: Cis-N-2-arylcyclohexylamines and their quaternary ammonium salts- two new series of cholinesterase inhibitors. PMID- 4150559 TI - Proceedings: Cyclohexane derivatives with muscarinic and anti-muscarinic actions. PMID- 4150560 TI - Proceedings: Neuromuscular blocking agents: the norcoralydine methiodides. PMID- 4150561 TI - Proceedings: Synthesis and characteristics of the enantiomers of the cyclic metabolite of methadone. PMID- 4150562 TI - Proceedings: A comparison of stationary phases for the g.l.c. of basic drugs. PMID- 4150563 TI - Proceedings: The spectrophotometric determination of ampicillin and cloxacillin in combined preparations. PMID- 4150564 TI - Proceedings: Modification and application of automated analysis for morphine. PMID- 4150565 TI - Proceedings: Molecular aggregation in aqueous bile salt-phosphatidylcholine solutions. PMID- 4150566 TI - Proceedings: Observations on the time-dependent behaviour of monolayers of 1,2 dipalmitoyl-L-3-phosphatidylethanolamine. PMID- 4150567 TI - Proceedings: The binding of 8-anilino-1-naphthalene sulphonate (ANS) to phosphatidylcholine and its displacement by indomethacin. PMID- 4150568 TI - Proceedings: The transport of penicillins across non-aqueous membranes in the presence of phospholipids. PMID- 4150569 TI - Proceedings: Studies on drug-nylon interactions. PMID- 4150570 TI - Proceedings: The effect of mixing time on the bulk properties of magnesium stearate-sand mixtures. PMID- 4150571 TI - Proceedings: The influence of excipient type and drug particle size upon a small scale mixing process. PMID- 4150572 TI - Proceedings: The use of adsorbents to prevent mottling in coloured tablets. PMID- 4150573 TI - Proceedings: The effect of surface active-agents on the zeta potential of particles in a model suspension system. PMID- 4150574 TI - Proceedings: Toxicity studies on some p-substituted acetanilides. PMID- 4150575 TI - Proceedings: Micellar properties of aqueous solutions of n-alkylpolyoxyethylene surfactants. PMID- 4150576 TI - Proceedings: The influence of alcohol chain length on the structure and rheology of emulsions stabilized by cetrimide-long chain alcohols. PMID- 4150577 TI - Proceedings: The effect of tetracyclines on the rheological properties of bronchial mucus. PMID- 4150579 TI - Proceedings: The strength, hardness and elasticity of moist films of gelatin. PMID- 4150578 TI - Proceedings: The effect of ageing on the rheological properties of gelatin gels. PMID- 4150580 TI - Proceedings: Metabolism of ephedrine on and near its basic centre. PMID- 4150581 TI - Proceedings: The importance of hydrolysis and N-oxidation in the in vitro metabolism of N-2-benzoyloxyethylnorfenfluramine (JP992--780SE). PMID- 4150582 TI - Proceedings: In vitro metabolic N-oxidation of the minor tobacco alkaloids, ( )methylanabasine and (-)anabasine to yield a hydroxylamine and a nitrone in lung and liver homogenates. PMID- 4150583 TI - Proceedings: Protein binding by equilibrium dialysis and equilibrium ultrafiltration: a comparative evaluation. PMID- 4150584 TI - Proceedings: Activation and inhibition of trypsin digestion of fibrin by sodium flufenamate. PMID- 4150585 TI - Proceedings: An esr titration technique for the determination of accessible tyrosyl and tryptophyl residues in globular proteins. PMID- 4150586 TI - Diffusion in sucrose solutions. PMID- 4150587 TI - The tensile strength and compression behaviour of lactose, four fatty acids, and their mixtures in relation to tableting. PMID- 4150588 TI - The stability of aqueous solutions of phenylephrine at elevated temperatures: identification of the decomposition products. PMID- 4150589 TI - Variation in delivery of isoprenaline from various pressurized inhalers. PMID- 4150590 TI - The effect of particle shape and crystal habit on properties of sodium chloride. PMID- 4150591 TI - A stable method for calculating oral drug absorption rate constants with two compartment disposition. PMID- 4150592 TI - A method of interpreting time-response curves. PMID- 4150593 TI - Scanning electron microscopy of nylon microcapsules. PMID- 4150594 TI - The anomalous behaviour of some oxyclozanide polymorphs. PMID- 4150595 TI - The influence on pharmaceutical granulation of the type and capacity of mixers. PMID- 4150596 TI - Strain recovery of compacts on extended storage. PMID- 4150597 TI - Stabilization of oil-in-water emulsions by alkyl sulphates: the effect of a long chain alcohol. PMID- 4150598 TI - A moisture transfer effect in hard gelatin capsules of sodium cromoglycate. PMID- 4150599 TI - The effects of alpha stimulation and alpha blockade on pulmonary vascular segment resistance in canine cardiogenic shock. PMID- 4150600 TI - Tyrosine aminotransferase induction in rat liver as a response to irradiation or flash burn injuries. PMID- 4150601 TI - Letter: Beta-blocking agents and platelet aggregation. PMID- 4150602 TI - Physician overpopulation. PMID- 4150603 TI - [The clinical course of severe carbromal poisoning (author's transl)]. PMID- 4150604 TI - [15th International Nursing Congress--I.C.N. (Mexico City, May 13-19, 1973)]. PMID- 4150605 TI - The effects of long term administration of psychotrophic drugs on human sleep. IV. The effects of chlorpromazine. PMID- 4150606 TI - The effects of long term administration of psychotropic drugs on human sleep. V. The effects of chloral hydrate. PMID- 4150607 TI - [Divonne 1973]. PMID- 4150609 TI - [Iatrogenic arrhythmia: parasystole in electrosystolic heart pacing]. PMID- 4150608 TI - [Pathology of pulmonary vasculitis with special consideration of Wegener's granulomatosis]. PMID- 4150610 TI - Brompheniramine and the cardio-vascular effects of norephedrine and noradrenaline. PMID- 4150612 TI - Radiochemical determination of the optical purity of L-amino acids. PMID- 4150611 TI - Disodium cromoglycate (Lomudal) in the treatment of hay fever. PMID- 4150613 TI - Biochemical procedures as aids in diagnosis of different forms of cancer. PMID- 4150614 TI - Effect of temperature on urocanase from a psychrophile, Pseudomonas putida. PMID- 4150615 TI - 25-Hydroxyvitamin D3-24-hydroxylase. Subcellular location and properties. PMID- 4150616 TI - Amino acid analyses of chymotrypsin-like proteases from the sea anemone (Metridium senile). PMID- 4150617 TI - Clinical pharmacology in endodontics and intracanal medicaments. PMID- 4150618 TI - Endodontic case reports. PMID- 4150619 TI - [Editorial: Hormonal influence of the thymus on the immunological system]. PMID- 4150620 TI - [Clinical treatment of lithium induced tremors with a beta receptor antagonist (propranolol)]. PMID- 4150621 TI - Current status of the physician's assistant in Oklahoma. PMID- 4150622 TI - Comparison of two experiences using physician's assistants. PMID- 4150623 TI - [Ventilatory and other effects of Sch 1000 aerosol in 54 patients with reversible bronchospasm]. PMID- 4150624 TI - Why Beta-blockade for hypertension? PMID- 4150625 TI - Proceedings: Mode of action of beta-adrenergic receptor blocking drugs in hypertension. PMID- 4150626 TI - Proceedings: Pharmacological effects of a combination of alpha- and beta blockers. PMID- 4150627 TI - Proceedings: Combined alpha and beta-receptor blockade in the treatment of severe hypertension. PMID- 4150629 TI - A panel discussion was held on "Present views on the management of hypertension". PMID- 4150628 TI - Proceedings: General practitioner studies of beta-blockade in hypertension. PMID- 4150630 TI - The occurrence of larvae of Strongylus edentatus in the testicles of stallions. PMID- 4150631 TI - [Animal experiments on the influence of diencephalon on the renal juxtaglomerular apparatus]. PMID- 4150632 TI - Relative value of various etiological factors in short lasting, adverse psychological reactions to cannabis smoking. PMID- 4150633 TI - The effect of beta blockade and-or physical training in patients with angina pectoris. PMID- 4150634 TI - [Prevention of dental caries at Deszk by fluoridation of table salt. VII. Changes in DMF indexes after a 5-year trial period]. PMID- 4150635 TI - Education for general practice--worldwide problems. PMID- 4150636 TI - Structure of medical care services in the U.S.S.R. PMID- 4150637 TI - Clinical study of dental caries and tongue thrust. PMID- 4150639 TI - [General and local postoperative therapy of inflammatory and obstructive vein diseases with BayroVas (author's transl)]. PMID- 4150640 TI - Measurement of Hill reactions and photoreduction. PMID- 4150641 TI - Photosensitization reactions of chlorophyll. PMID- 4150643 TI - [French-Polish Neurology Symposium. Inaugural address]. PMID- 4150644 TI - [French-Polish Neurology Symposium. Inaugural address]. PMID- 4150645 TI - [Alpha-adrenergic blockade in the treatment of burn shock]. PMID- 4150646 TI - [Use of viadril in pathological labor and in certain extragenital diseases]. PMID- 4150647 TI - [Certain diagnostic criteria of periarteritis nodosa and pheochromocytoma in children]. PMID- 4150648 TI - [Enzymatic, electron microscopic and polarographic characteristics of isolated rat brain mitochondria. I. New method of separation]. PMID- 4150649 TI - The effects of iron-limited growth on the reduced nicotinamide-adenine dinucleotide dehydrogenase activity and the membrane proteins of Candida utilis mitochondria. AB - 1. The mitochondrial NADH dehydrogenase (EC 1.6.99.3) of Candida utilis exhibited altered properties when the organism was grown under iron-limited conditions. No suitable acceptor was found for assay of this enzyme from iron-limited cells. 2. Mitochondrial membrane proteins from C. utilis were analysed by polyacrylamide gel electrophoresis. Compared with glycerol-limited cells, iron limitation resulted in the loss of at least two polypeptides from the mitochondrial membrane. 3. Neither of the polypeptides affected by iron limitation was part of a cytochrome, although one of them was part of the mitochondrial NADH dehydrogenase. 4. Non-haem iron of mitochondrial membranes was released in the presence of sodium dodecyl sulphate, and electrophoresis in solutions of this detergent cannot be used directly to identify iron-sulphur proteins. Non-ionic detergents do not release non-haem iron but nor do they provide a satisfactory system for electrophoretic separation. PMID- 4150650 TI - Role of mixed-function amine oxidases in N-hydroxylation of 2-acetamidofluorene by hamster liver microsomal preparations. AB - Pretreatment of hamsters with 3-methylcholanthrene (100mg/kg body wt.) 24h before death did not appreciably change the extent of N-oxide formation when hepatic microsomal preparations were incubated with NN-dimethylaniline as substrate. In contrast, the N-hydroxylation of 2-acetamidofluorene was increased severalfold in hepatic microsomal preparations from pretreated animals. Under these conditions there were no appreciable changes in cytochrome P-450 content and NADPH cytochrome c reductase activity. On the basis of these comparative data, it is suggested that amine oxidase is not involved in N-hydroxylation of 2 acetamidofluorene. PMID- 4150651 TI - Studies on selenium incorporation into, and electron-transfer function of, liver microsomal fractions from normal and vitamin E-deficient rats given phenobarbitone. AB - 1. The incorporation of (75)Se from Na(2) (75)SeO(3) into the liver endoplasmic reticulum of rats given phenobarbitone was investigated by using a zonal centrifuge technique. 2. It was found that, in rats deprived of vitamin E, or of vitamin E and selenium, phenobarbitone was without effect on the incorporation of (75)Se or on its conversion to (75)Se(2-). When vitamin E was given at the same time as the phenobarbitone and (75)Se, there was a large increase in the amount of (75)Se and (75)Se(2-) found in the smooth reticulum. It is concluded that there may be a specific vitamin E-dependent role for selenium and selenide in the smooth endoplasmic reticulum, and it is suggested, in the light of these and other observations, that the selenide may form a part of the active centre of a non-haem iron-containing protein ;X', that may function in microsomal electron transport. 3. Measurements of the contents of cytochromes P-450 and b(5) in liver microsomal fractions of rats given vitamin E-deficient, and vitamin E- and selenium-deficient diets, showed that haemoprotein biosynthesis is unimpaired in these rats and phenobarbitone treatment resulted in the expected increase in the haemoproteins. 4. When the reduction of cytochrome P-450 by NADH and NADPH was measured, no difference was found between normal and deficient animals. 5. These results are discussed in relation to current knowledge of microsomal electron transfer. PMID- 4150652 TI - The reconstitution of oxidase activity in membranes derived from a 5 aminolaevulinic acid-requiring mutant of Escherichia coli. AB - 1. The reconstitution of oxidase activity in cell-free extracts of a mutant of Escherichia coli K12Ymel, that require 5-aminolaevulinic acid for growth on non fermentable carbon sources, is described. 2. The reconstitution is dependent on haematin or a haem extract from a prototrophic strain of E. coli, and the product of the reaction has been identified as NADH-reducible cytochrome b. 3. The requirement for haematin cannot be replaced by four other porphyrins. Coproporphyrin III does not inhibit the haematin-dependent reconstitution, mesoporphyrin IX and protoporphyrin IX apparently compete with haematin for a binding site on the cytochrome apoprotein(s) and deuteroporphyrin IX binds to cytochrome apoprotein(s) and cannot be subsequently replaced by haematin. 4. The properties of electron-transport particles from cell-free extracts of the mutant strain, grown aerobically in the presence or absence of 5-aminolaevulinic acid, are described. In the absence of 5-aminolaevulinic acid no detectable cytochromes are produced, and oxidase activities are lowered but there is no apparent effect on the activities of the NADH dehydrogenase and d-lactate dehydrogenase. 5. The reconstitution of oxidase activity by electron-transport particles from cells grown in the absence of 5-aminolaevulinic acid requires ATP and haematin, and the product of the reaction was identified as NADH-reducible cytochrome b. 6. It is concluded that the cytochrome apoproteins are synthesized and incorporated into the cytoplasmic membrane of E. coli in the absence of haem synthesis. The subsequent reconstitution of functional cytochrome(s) requires protohaem, but the nature of the side chain on the 2 and 4 positions of the porphyrin appears to be important. PMID- 4150653 TI - Isoenzyme patterns in parenchymal and non-parenchymal cells isolated from regenerating and regenerated rat liver. AB - Parenchymal and non-parenchymal cells were isolated from adult rat liver that had been fully regenerated after a 70% partial hepatectomy. The characteristics of the parenchymal cell preparations from regenerated rat liver indicated that they were a homogeneous population and comparable with parenchymal cells isolated from intact liver. The parenchymal cells from regenerated adult rat liver contain glucokinase, hexokinase, pyruvate kinase type I and aldolase B. The non parenchymal cells contain hexokinase, pyruvate kinase type III and aldolase B. When cells were isolated at different times of the day from rats on controlled feeding schedules, variation of tyrosine aminotransferase activity and liver glycogen content were observed in the parenchymal cells in keeping with the reported diurnal oscillations found in whole liver extracts. When parenchymal cells were isolated from rats 48 and 72h after partial hepatectomy, different isoenzyme patterns were observed. These cells appeared to synthesize pyruvate kinase type III, a function that was assigned previously to non-parenchymal cells or to foetal rat liver hepatocytes. PMID- 4150654 TI - Effects of membrane depolarization on nicotinamide nucleotide fluorescence in brain slices. AB - 1. Simultaneous measurement of tissue NAD(P)H fluorescence and respiration was used to elucidate some of the early chemical changes after depolarization of the membranes of cerebral-cortical cells. Depolarization was effected by the application of a train of short-duration voltage pulses across a slice of guinea pig cerebral cortex. The pulses cause a biphasic change in fluorescence corresponding to an early (within 1s) oxidation and later (about 10s) reduction of nicotinamide nucleotide. The major portions of both these redox changes are unrelated to the accompanying increase in slice respiration of about 75%. 2. The early oxidation requires Ca(2+) and phosphate in the bathing medium and appears to be largely due to an early mitochondrial uptake of these ions. 3. The ensuing reduction occurs in the cytosol, as judged by its almost complete elimination in the presence of exogenous pyruvate. It becomes markedly attenuated with increasing time of incubation. This and the ability of exogenous 6-N-2'-O dibutyryl cyclic AMP to cause a reduction in the absence of electrical pulses suggest that it results from a cyclic AMP-mediated activation of glycogenolysis. 4. Further results, obtained in the presence of exogenous pyruvate, indicate that in addition to the above effects a net transfer of NADH from the mitochondrial to cytosolic space (presumably via a shuttle mechanism) is activated by the electrical pulses. 5. The lack of any sizeable (more than 2% of basal fluorescence) fluorescence change associated with the respiratory increase caused by the pulses, and the fact that any change which may be associated with it corresponds to a small reduction of mitochondrial nicotinamide nucleotide, show that a simple state 4 --> state 3 mitochondrial transition cannot account for the increased respiration. The results suggest, rather, a co-ordinated control of respiration, at more than one site. PMID- 4150655 TI - Synthesis of 3- and 4-O-beta-D-galactopyranosyl-L-rhamnose, and of 3-O-(2 acetamido-2-deoxy-beta-D-glucopyranosyl)-L-rhamnose, and their use in precipitin inhibition studies with type VII antipneumococcal serum. PMID- 4150657 TI - Hospital sponsors rural facility. PMID- 4150656 TI - Ion transport across the erythrocyte membrane. PMID- 4150658 TI - The regulation of glutamine metabolism in Candida utilis: studies with 15NH3 to measure in vivo rates of glutamine synthesis. PMID- 4150659 TI - The regulation of glutamine metabolism in Candida utilis: the role of glutamine in the control of glutamine synthetase. PMID- 4150660 TI - The regulation of glutamine metabolism in Candida utilis: the inactivation of glutamine synthetase. PMID- 4150661 TI - Identification and quantitative determination of phenothiazine drugs in urine samples of psychiatric patients. PMID- 4150662 TI - [Radioimmunoassay of digitalis]. PMID- 4150663 TI - Prescribing patterns in the New York City Medicaid program. PMID- 4150664 TI - [Isolated panarteritis of the coronary arteries in infancy (author's transl)]. PMID- 4150665 TI - [Possibility of determining mosquito females (Culicidae) from microscopic preparations of the head. 3. Species key (excluding Aedes)]. PMID- 4150666 TI - [Fauna and biology of the mosquitoes of the basin of the lower course of the Vilyui]. PMID- 4150667 TI - Review lecture on the growth and form of a bacterial cell. PMID- 4150668 TI - [Effect of urography and arteriography on urinary excretion of various enzymes]. PMID- 4150669 TI - MMPI indices of personality change following short- and long-term hospitalization of heroin addicts. PMID- 4150670 TI - Effectiveness of marathon group psychotherapy with hospitalized female narcotics addicts. PMID- 4150671 TI - Self-concept of neurotic and sociopathic criminal offenders. PMID- 4150672 TI - An abbreviated MMPI for use with college students. PMID- 4150673 TI - [Caries incidence in 7-15-year-old schoolchildren in Basel during 1972, following a 10-year drinking water fluoridation period]. PMID- 4150674 TI - [Results of dental examination of Basel schoolchildren in 1973]. PMID- 4150675 TI - [The caries-inhibiting property of a Na2FPO3 toothpaste after 4-year use]. PMID- 4150676 TI - [Reflex reactions of resistant and capacitative vessels of the skeletal musculature before and after the administration of ganglionic blockaders]. PMID- 4150677 TI - Immunologic disorders in the dog and cat. PMID- 4150679 TI - [Vaccination against measles]. PMID- 4150678 TI - Pharmacologic management of allergic diseases. PMID- 4150680 TI - Studies on the metabolism of ethynylestradiol in vitro and in vivo: the significance of 2-hydroxylation and the formation of polar products. PMID- 4150682 TI - Effect of drugs and alcohol on psychomotor skills related to driving. PMID- 4150681 TI - The metabolism of sympathomimetic bronchodilator drugs by the isolated perfused dog lung. PMID- 4150684 TI - Editorial: Drug Metabolism and Disposition: the biological fate of chemicals. PMID- 4150683 TI - Physical urticaria. Its diagnosis and treatment. PMID- 4150685 TI - A rapid method for the mass spectrometric identification of glucuronides and other polar drug metabolites in permethylated rat bile. PMID- 4150686 TI - The use of mass spectroscopy and 13C and 1H nuclear magnetic resonance in the characterization of 1-methyl-(2, 6-xylyloxy)ethylamine metabolites. PMID- 4150687 TI - Examination of extinction coefficients of soluble and membrane-bound cytochromes P-450 and P-420. PMID- 4150688 TI - Absorption, distribution, and excretion of quingestanol acetate by the rat. PMID- 4150690 TI - Mammalian metabolism of terpenoids. I. Reduction and hydroxylation of camphor and related compounds. PMID- 4150689 TI - Metabolic disposition of 18-homoestriol in the rat, dog, and man. PMID- 4150691 TI - Clinical and pharmacological investigations of the psychobiology of the affective disorders. PMID- 4150692 TI - A virological study of post-vaccinal encephalitis. AB - In the province of Voyvodina 18 cases of post-vaccinal encephalitis have been recorded, three of which were fatal.The estimated morbidity rate was 0.6 per 10(5) after revaccination, and 3.9 per 10(5) after primary vaccination. The virological studies described, as well as other findings referred to in this report, are consistent with the possibility of an autoimmune aetiology of the post-vaccinal encephalitis cases observed. PMID- 4150693 TI - Skin reactivity and antibody response following vaccination against smallpox. AB - Revaccination between 2 and 5 years after the last vaccination induced higher complement-fixation titres than revaccination 7-63 years after the last vaccination. The highest CF titres were reached during the 3rd to the 5th week after vaccination.Fifty-two serum samples, taken 137 or more days after a successful vaccination, all showed CF titres lower than 1/2.In a group of successfully vaccinated persons with no post-vaccinal complications, 65 out of 66 had a successful ;take' after one or two subsequent vaccinations.Sera of persons receiving primary vaccination showed significantly lower CF titres than sera of revaccinated persons. Cases of post-vaccinal encephalitis showed greater antibody response than uncomplicated successfully vaccinated cases in both the primary vaccination and revaccination groups. The antibody response in revaccinated persons with post-vaccinal encephalitis was greater than that in the group of successfully revaccinated cases without encephalitis.A group of 26 naturally hyporeactive persons completely failed to ;take' even after vaccination repeated between 3 and 10 times (average 5 times per person). The frequency of seropositives in this group, and the height of their CF titres, were significantly lower than in the group of successfully vaccinated persons. These findings support the view that untreated persons who repeatedly fail to ;take' with the vaccine must not be considered immune.In vaccinated persons treated with immunoglobulin (with or without simultaneous treatment with Marboran) antibody production was apparently diminished. Treatment of patients with Marboran significantly lowers the capacity of the vaccine to ;take'. PMID- 4150694 TI - Sea nettle and man-o'war venoms: a chemical comparison of their venoms and studies on the pathogenesis of the sting. PMID- 4150695 TI - Complications of occult pneumococcal bacteremia in children. PMID- 4150696 TI - Rates of synthesis and degradation of hepatic acetyl CoA carboxylase in fed, fasted, fasted-refed, and diabetic rats. PMID- 4150697 TI - [Controversy with respect to smallpox vaccination and new vaccination methods]. PMID- 4150698 TI - [Blockade of histamine receptors H-2 and gastric secretion]. PMID- 4150699 TI - Is pre-employment medical examination of value? The validity of a computerized health questionnaire. PMID- 4150700 TI - The relationship of testicular tumours to maldescent. PMID- 4150701 TI - [Protection against histamine bronchospasm and Herxheimer anaphylactic microshock using a bile extract]. PMID- 4150702 TI - [Comparative clinico-morphological characteristics of changes in the lungs in collagen diseases]. PMID- 4150703 TI - Quantification of serum creatine phosphokinase isoenzyme activity. PMID- 4150704 TI - Hepatorenal toxicity following fluroxene anesthesia. PMID- 4150705 TI - Clinical recognition of leprosy: some factors leading to delays in diagnosis. AB - The case histories of eight patients in the United Kingdom admitted to hospital for the diagnosis of leprosy are examined in detail. Review of their early symptoms and signs showed that there had been delays in diagnosis, ranging from a few months to many years. Possible reasons for delay are discussed, and attention is called to the importance of nasal symptoms in the early diagnosis of lepromatous leprosy. PMID- 4150706 TI - Editorial: Adverse reactions to beta-adrenergic blockade. PMID- 4150707 TI - Increased tyrosine hydroxylase activity in the locus coeruleus of rat brain stem after reserpine treatment and cold stress. PMID- 4150708 TI - Direct conversion of 17beta-estradiol-3-glucosiduronate and 17beta-estradiol-3 sulfate to their 17-keto forms by human kidney homogenates. PMID- 4150709 TI - Gamma-glutamyl transpeptidase of rat kidney. Some properties and kinetic constants. PMID- 4150710 TI - Inhibition of acid secretion in dog by metiamide, a histamine antagonist acting on H2 receptors. PMID- 4150711 TI - DPT as an adjunct in psychotherapy of alcoholics. PMID- 4150712 TI - A controlled evaluation of pyrovalerone in chronically fatigued volunteers. PMID- 4150713 TI - D- and L-isoleucine metabolism and regulation of their pathways in Pseudomonas putida. AB - Pseudomonas putida oxidized isoleucine to acetyl-coenzyme A (CoA) and propionyl CoA by a pathway which involved deamination of d-isoleucine by oxidation and l isoleucine by transamination, oxidative decarboxylation, and beta oxidation at the ethyl side chain. At least three separate inductive events were required to form all of the enzymes of the pathway: d-amino acid dehydrogenase was induced during growth in the presence of d-isoleucine; branched-chain keto dehydrogenase was induced during growth on 2-keto-3-methylvalerate and enzymes specific for isoleucine metabolism; tiglyl-CoA hydrase and 2-methyl-3-hydroxybutyryl-CoA dehydrogenase were induced by growth on isoleucine, 2-keto-3-methylvalerate, 2 methylbutyrate, or tiglate. Tiglyl-CoA hydrase and 2-methyl-3-hydroxybutyryl-CoA dehydrogenase were purified simultaneously by several enzyme concentration procedures, but were separated by isoelectric focusing. Isoelectric points, pH optima, substrate specificity, and requirements for enzyme action were determined for both enzymes. Evidence was obtained that the dehydrogenase catalyzed the oxidation of 2-methyl-3-hydroxybutyryl-CoA to 2-methylacetoacetyl-CoA. 2-Methyl-3 hydroxybutyryl-CoA dehydrogenase catalyzed the oxidation of 3-hydroxybutyryl-CoA, but l-3-hydroxyacyl-CoA dehydrogenase from pig heart did not catalyze the oxidation of 2-methyl-3-hydroxybutyryl-CoA; therefore, they appeared to be different dehydrogenases. Furthermore, growth on tiglate resulted in the induction of tiglyl-CoA hydrase and 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, but these two enzymes were not induced during growth on crotonate or 3 hydroxybutyrate. PMID- 4150715 TI - Letter: Plasma enzymes in liver disease. PMID- 4150714 TI - Regulation of leucine catabolism in Pseudomonas putida. AB - The generation time of Pseudomonas putida with l-leucine was 20 h in synthetic media but only 3 h with d-leucine. Slow growth in the presence of l-leucine was partially overcome by addition of 0.1 mM amounts of either d-valine, l-valine, or 2-ketoisovalerate. The activities of five enzymes which take part in the oxidation of leucine by P. putida were measured under various conditions of growth. Four enzymes were induced by growth with dl-leucine as sole source of carbon: d-amino acid dehydrogenase, branched-chain keto acid dehydrogenase, 3 methylcrotonyl-coenzyme A carboxylase, and 3-hydroxy-3-methylglutaryl-coenzyme A lyase. The segment of the pathway required for oxidation of 3-methylcrotonate was induced by growth on isovalerate or 3-methylcrotonate without formation of the preceding enzymes. The synthesis of carboxylase and lyase appeared to have been repressed by the addition of l-glutamate or glucose to cells growing on dl leucine as the sole carbon source. Mutants unable to grow at the expense of isovalerate had reduced levels of carboxylase and lyase, whereas the levels of three enzymes common to the catabolism of all three branched-chain amino acids and those of two isoleucine catabolic enzymes were normal. PMID- 4150716 TI - [Adrenergic beta receptor blockaders and nitrites in the treatment of angina pectoris]. PMID- 4150717 TI - B-cell alloantigens determined by the H-2 linked Ir region are associated with mixed lymphocyte culture stimulation. AB - Cell surface antigens, controlled by genes located in the Ir region of the murine major histocompatibility complex, are shown serologically to be expressed preferentially on bone marrow-derived lymphocytes. These antigens may play a major role as stimulators in mixed lymphocyte cultures. PMID- 4150718 TI - Factors of human chronic pain: an analysis of personality and pain reaction variables. AB - Factor analysis of pain and personality test data obtained from 119 patients with chronic pain syndromes yields seven factors: four composed of personality measures, two involving different psychophysical pain measures, and one sex related factor. The chief factors, comprising more than 50 percent of the total variance, are "interpersonal alienation and manipulativeness," "clinical pain intensity", and "pain endurance." PMID- 4150719 TI - [Depot preparations in psychiatry]. PMID- 4150720 TI - [Combination of beta blockaders with vasodilator substances in hypertension]. PMID- 4150721 TI - [Effect of catecholamines on the resistance and capacity of the coronary vessels]. PMID- 4150723 TI - [Bacterial neuraminidases: some physiochemical and biological properties and their relationship to microbial pathogenicity]. PMID- 4150722 TI - [Role of adrenergic mechanisms in pharmacological actions on the cerebral circulation]. PMID- 4150724 TI - [Effect of controlled hypotension on reducing the blood loss in otorhinolaryngological operations]. PMID- 4150725 TI - Increase in plasma alpha-lipoproteins in chronic alcoholics after acute abuse. PMID- 4150726 TI - Stress-induced gastric lesions in spontaneously hypertensive rats. Involvement of autonomic neurotransmitter substances. PMID- 4150727 TI - Crohn's disease of the mouth. PMID- 4150728 TI - Serum gonadotropins in cryptorchidism. An indicator of functional testes. PMID- 4150729 TI - The popliteal node assay for graft-versus-host interaction in mice. I. Location and proliferation of donor and host cells within the popliteal node. PMID- 4150730 TI - Drug-induced capillaritis. PMID- 4150732 TI - A quantitative ultrastructural and biochemical analysis of the process of reinnervation of the superior cervical ganglion in the adult rat. PMID- 4150731 TI - Regulation of 'malic' enzyme of Solanum tuberosum by metabolites. AB - A purification of ;malic' enzyme from potato is described. The purified enzyme is specific for NADP and requires a bivalent cation for activity. At pH values below 7 the plot of rate versus malate concentration approximates to normal Michaelis Menten kinetics. At pH values above 7 the plot of rate versus malate concentration is sigmoid. A number of dicarboxylic acids activate the enzyme and remove the sigmoidicity. The enzyme is inhibited by phosphate, triose phosphates and AMP. In general, effectors of the oxidative decarboxylation of malate behave in the same manner in the reductive carboxylation of pyruvate. The response of the enzyme to energy charge is reported and the physiological significance of the response to metabolites is discussed in relation to the proposed role of the enzyme in the control of pH. PMID- 4150733 TI - Glucaric acid as an indicator of use of enzyme-inducing drugs. PMID- 4150734 TI - Entamoeba histolytica. I. Aerobic metabolism. PMID- 4150735 TI - [Quantification of human factors by means of heart rate and sinus arrhythmia (indicators of mental load and fatigue) (author's transl)]. PMID- 4150736 TI - The use of ritodrine in the treatment of premature labour. PMID- 4150737 TI - Editorial: Prescribing habits of Australian doctors. PMID- 4150738 TI - BCG in cancer immunotherapy: results obtained with various BCG preparations in a screening study for systemic adjuvants applicable to cancer immunoprophylaxis or immunotherapy. PMID- 4150740 TI - Fluoridation--the alternative. (b) The pattern of dental caries. PMID- 4150739 TI - Cryptorchidism in a family with Kallmann's syndrome. PMID- 4150741 TI - [Is lung puncture aspiration a harmless procedure?]. PMID- 4150742 TI - [Antihypertensive action of a beta-blocker: value of a controlled therapeutic trial]. PMID- 4150743 TI - Primary skin actinomycosis of the chest wall. PMID- 4150744 TI - [Isolation of kidney antigen in the blood and urine of recipients in kidney transplantation]. PMID- 4150745 TI - [Laryngeal diseases in respiratory infections]. PMID- 4150746 TI - [Characteristics of the clinical course and treatment of the most widespread otorhinolaryngological diseases in the North]. PMID- 4150747 TI - Endogenous formation of carbon monoxide and methane at elevated pressure. PMID- 4150748 TI - Macula-sparing monocular blackouts. Clinical and pathologic investigations of intermittent choroidal vascular insufficiency in a case of periarteritis nodosa. PMID- 4150749 TI - Diplococcus pneumoniae osteomyelitis in an infant with sickle cell anemia. PMID- 4150750 TI - The development of bioluminescence in the ctenophore Mnemiopsis leidyi. PMID- 4150751 TI - Banff Conference on Dental Auxiliaries. The winds of change. PMID- 4150752 TI - The relationship between age and engagement in pleasant activities. PMID- 4150753 TI - [Influence of non-barbituate drugs on the bioelectrical activity of the brain]. PMID- 4150754 TI - [Radiation levels and the effect of radiation]. PMID- 4150756 TI - Letter: "Gamma-glutamyl cycle". PMID- 4150755 TI - [Use of type II drugs in neuroleptoanalgesia combined with Gamma OH in the blind maneuver of naso-tracheal intubation. Causes of difficulties in endotracheal intubation: classification]. PMID- 4150757 TI - [Alarming acute attacks in Basedow's thyrotoxicosis]. PMID- 4150758 TI - Hydroxylation of taurolithocholate by isolated human liver microsomes. I. Identification of metabolic product. PMID- 4150759 TI - [Alpha and beta adrenergic control of muscle tonus]. PMID- 4150761 TI - Proceedings: The pharmokinetics of rimiterol in asthmatic patients. PMID- 4150760 TI - Assessment of selective beta-adrenoceptor blockade in man. AB - 1. Selective antagonism of the cardiac beta(1)-adrenoceptors has been studied in normal human volunteers.2. Practolol and UK 6558 produced greater antagonism of the chronotropic and inotropic responses to i.v. isoprenaline than of the vasodilator response to either i.v. or intra-arterial isoprenaline. A third drug, M&B 17,803A, produced non-selective beta-adrenoceptor blockade in 2 of 3 subjects studied.3. Practolol, UK 6558 and M&B 17,803A, produced an attenuation of the responses to Valsalva's manoeuvre.4. A substantial reduction in blood pressure was seen in 3 of 4 normotensive subjects given UK 6558. PMID- 4150762 TI - Proceedings: Preliminary observations on the human pharmacology of I.C.I. 66082 in normal volunteers. PMID- 4150763 TI - Proceedings: Inhibition of phenytoin metabolism by sulthiame. PMID- 4150764 TI - A comparative study of some convulsant substances as gamma-aminobutyric acid antagonists in the feline cerebral cortex. AB - 1. By the use of microiontophoretic techniques, quantitative estimates were obtained of the depressant effects of gamma-aminobutyric acid (GABA) on single feline cortical neurones.2. Picrotoxin, bicuculline, strychnine, (+) tubocurarine, penicillin and leptazol were also applied microiontophoretically to single neurones. Sequential GABA applications were made before, during and after the microiontophoresis of these substances and any effects on the time course of the GABA depression were measured as an estimate of antagonism or potentiation of GABA.3. (+)-Tubocurarine was found to be a potent GABA antagonist. Picrotoxin and bicuculline were rather less potent and strychnine and penicillin only weakly active as GABA antagonists. Leptazol appeared to be inactive against GABA depressions.4. In addition, bicuculline and strychnine were found to be capable of potentiating the depressant action of GABA. This property was not shared by the other substances studied.5. All the substances studied produced changes in neuronal firing rate that did not correlate with GABA antagonism.6. In conclusion, several potent convulsants have been shown to be capable of GABA antagonism. It is not yet clear that this effect, rather than a direct effect on neuronal excitability, is the prime mechanism behind their convulsant properties. PMID- 4150765 TI - [Diagnosis and therapy of the secondary disease: psychiatry]. PMID- 4150766 TI - The effects of carbon source on glutamate dehydrogenase activities in Aspergillus nidulans. PMID- 4150767 TI - D-amino acid dehydrogenase: the enzyme of the first step of D-histidine and D methionine racemization in Salmonella typhimurium. PMID- 4150768 TI - Complementation studies of lethal alleles in the mouse causing deficiencies of glucose-6-phosphatase, tyrosine aminotransferase, and serine dehydratase. AB - The pleiotropic effects of six radiation-induced lethal alleles at the albino locus in the mouse include deficiencies of various enzymes and of serum proteins. Closely correlated with the biochemical deficiencies are severe ultrastructural abnormalities of endoplasmic reticulum membranes and the Golgi apparatus in liver and kidney cells. Complementation studies led to the distinction of four different complementation groups among the six lethal alleles. The results are compatible with the interpretation that the six lethal alleles represent overlapping deletions of various sizes at and around the albino locus in the mouse, in a region concerned with the control of biochemical and structural differentiation. PMID- 4150769 TI - Incomplete restoration of the bursa-dependent immune system after transplantation of allogeneic stem cells into immunodeficient chicks. AB - Transplantation of allogeneic cells from bursa of Fabricius into cyclophosphamide treated, immunodeficient chicks resulted in immunological tolerance to donor line skin grafts; graft-versus-host disease did not occur. Allogeneic bursal stem cells taken from 3-day-old donors induced restoration of bursal morphology, of antibody formation to Brucella abortus and of occurrence of pyroninophilic cells and immunoglobulin-bearing cells in the peripheral lymphoid tissues. Secondary response to sheep red blood cells and production of germinal centers were not restored. Transplantation of histocompatible bursal stem cells resulted in a complete reconstitution of the bursa-dependent lymphoid system, both in function and in morphology. Allogeneic postbursal stem cells taken from the bursa of 10 week-old donors had a reconstitutive effect only on the production of antibodies to Brucella. Transplanted stem cells maintained their functional potential in the allogeneic environment, since, when transferred back to histocompatible hosts, they displayed normal function. These findings indicate that a complete functional and morphological restoration of the bursa-dependent immune system cannot be achieved without identity of the donor and recipient at loci near to or identical with those determining the major histocompatibility antigens, even though graft-versus-host disease is avoided. This identity permits a full cooperation of the donor and host cells. PMID- 4150770 TI - The drug therapy of ulcerative colitis and of Crohn's disease. PMID- 4150771 TI - A comparison of the effects of antihistamines on platelet function. PMID- 4150772 TI - The in vivo and in vitro effect of antihistamines on platelet aggregation. PMID- 4150773 TI - [The mortality from ulcerative colitis in Denmark 1960-69]. PMID- 4150774 TI - Sympathectomy for hypertension. PMID- 4150775 TI - Enhancement of ganglionic muscarinic activity by gallamine. PMID- 4150776 TI - [Laboratory tests with various higher alcohols as mosquito larvicides]. PMID- 4150777 TI - A new parasite of mosquitoes, Reeismermis muspratte sp.nov. (Nematoda: Mermithidae), with notes on its life-cycle. PMID- 4150778 TI - Some quantitative aspects of flight muscle damage in mosquitoes infected with filarial larvae. PMID- 4150779 TI - Conversion of carbon 4 of malate into products of the pentose cycle by isolated bundle sheath strands of Digitaria sanguinalis (L.) Scop. leaves. PMID- 4150780 TI - Changes in hepatic fatty acid synthesis following glucagon injections in vivo. PMID- 4150781 TI - The effect of sulthiame on disturbed behaviour in mentally subnormal patients. PMID- 4150782 TI - Histogenesis and dependent glutamine synthetase inducibility in embryonic neural retina. Irreversible inhibition of differentiation by 5-bromodeoxyuridine. PMID- 4150783 TI - Terbutaline: a preliminary report of its pharmacological properties and therapeutic efficacy in asthma. PMID- 4150784 TI - [Reference values for the determination of GOT, GPT, and alkaline phosphatase in serum with optimal standard methods (author's transl)]. PMID- 4150785 TI - [Etiology and therapy of perioral dermatitis]. PMID- 4150786 TI - [Letter: Limits of medical fees for services of the attending physician]. PMID- 4150787 TI - [Therapeutic use of agents acting on alpha and beta receptors]. PMID- 4150788 TI - [Guidelines for beta-sympathicolytic therapy]. PMID- 4150789 TI - Segmental aneuploidy and enzyme activity as a method for cytogenetic localization in drosophila melanogaster. AB - A method of mapping genes which specify enzymes without the necessity of obtaining genetic variants has been explored. Three enzymes whose structural genes have known genetic positions were chosen to see if the relationship between gene dosage and enzyme activity could be used as a tool in cytological localization. Zw, the gene specifying G6PD, is located in the X chromosome region, 18D-18F. The structural gene for 6PGD, Pgd, maps in the X chromosome bands 2C1-2E1. Idh-NADP, the gene which specifies IDH-NADP, is found on the third chromosome, in bands 66B-67C. PMID- 4150790 TI - Caries-inhibition by an amine fluoride dentifrice results after 6 years in children with low caries activity. PMID- 4150791 TI - In vitro activity of levamisole on the infective larvae, microfilariae and adult worms of Breinlia Sergenti. PMID- 4150792 TI - Role of amines in anaphylactic contraction of guinea pig isolated smooth muscle. PMID- 4150793 TI - Uridine diphosphate galacturonate 4-epimerase from the blue-green alga Anabaena flos-aquae. PMID- 4150794 TI - Steroid receptors and the mechanism of the specificity of glucocorticoid responsiveness of somatic cell hybrids between hepatoma tissue culture cells and mouse fibroblasts. PMID- 4150795 TI - Mitochondrial omega-hydroxylation of cholesterol side chain. PMID- 4150796 TI - Aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction in rat liver cells in culture. PMID- 4150797 TI - Evidence for the participation of cytochrome b5 in plasmalogen biosynthesis. PMID- 4150798 TI - The role of antibiotics in the management of open fractures. PMID- 4150799 TI - Ultrastructural study of effect of methionine sulfoximine on developing and adult rat cerebral cortex. PMID- 4150800 TI - Studies on brain biopsies of patients with Huntington's chorea. PMID- 4150801 TI - The occurrence in and actions of amino acids on isolated supra oral sphincter preparations of the sea anemone Actinia equina. AB - 1. L-glutamic acid reversibly inhibits the contractions of isolated circular muscle preparations from different body regions of the sea anemone Actinia equina to electrical stimulation.2. L-glutamic acid does not cause inhibition of contraction by conversion to ammonia or gamma-amino-butyric acid, but appears to act on a glutamate receptor.3. It is postulated that in Actinia equina there is a receptor for glutamic acid whose structural requirements for activation are met by comparatively few analogues of glutamic acid. Of thirty-four analogues tested, only seven were active, most were less active, and only homocysteic acid had a greater activity than L-glutamic acid.4. Glutamic acid does not depress conduction of contraction in circular muscle preparations.5. The inhibition produced by L-glutamic acid does not appear to be conducted from one part of a preparation to another.6. Glutamic acid occurs in high concentrations in supra oral sphincter preparations of Actinia equina.7. Glutamic acid is released into sea water from sphincter preparations at rest and the amount released is increased by electrical stimulation of the preparation. However, many other amino acids are released at rest and following electrical stimulation, so that it is difficult to suggest that glutamic acid may be involved as a neurotransmitter in the sea anemone. PMID- 4150802 TI - Letter: Estrogen effects on phenothiazine derivative blood levels. PMID- 4150803 TI - Editorial: Drugs for anxiety. PMID- 4150804 TI - [Letter: Kidney punch biopsy in a case of periarteritis nodosa]. PMID- 4150805 TI - Gamma glutamyl transpeptidase in normal pregnancy. PMID- 4150806 TI - The properties of adrenal zona glomerulosa cells after purification by gravitational sedimentation. PMID- 4150807 TI - Orchidectomy and the immune response. I. Effect of orchidectomy on lymphoid tissues of mice. PMID- 4150808 TI - Orchidectomy and the immune response. II. Response of orchidectomized mice to antigens. PMID- 4150809 TI - [Bladder-neck function and sexual disorders following rectum amputation or rectum resection and retroperitoneal lymphdenectomy]. PMID- 4150810 TI - [Problems in ingestive and bactericidal phagocytosis demonstrated by examples of antimicrobial phagocytosis]. PMID- 4150811 TI - Oxidative phosphorylation in Escherichia coli K12. An uncoupled mutant with altered membrane structure. AB - 1. A new mutant strain (AN228) of Escherichia coli K12, unable to couple phosphorylation to electron transport, has been isolated. The mutant allele (unc 405), in strain AN228, was found to map near the uncA and uncB genes at about minute 74 on the E. coli genome. 2. A transductant strain (AN285) carrying the unc-405 allele is similar to the uncA and uncB mutants described previously in that it is unable to grow on succinate, gives a low aerobic yield on limiting concentrations of glucose, has a normal rate of electron transport, is unable to couple phosphorylation to electron transport, and lacks ATP-dependent transhydrogenase activity. 3. Strain AN285 (unc-405) is similar to an uncA mutant, but different from an uncB mutant, in that it is unable to grow anaerobically in a glucose-mineral-salts medium, and membrane preparations do not have Mg(2+)-stimulated adenosine triphosphatase activity. 4. Strain AN285 (unc 405) does not form an aggregate analogous to the membrane-bound Mg(2+)-stimulated adenosine triphosphatase aggregate found in normal cells. In this respect it differs from strain AN249 (uncA(-)), which forms an inactive membrane-bound Mg(2+)-stimulated adenosine triphosphatase aggregate. PMID- 4150812 TI - Microsomal enzyme activity in perfused rat liver. PMID- 4150814 TI - Metabolic rate of phenacetin and of paracetamol in dogs before and after treatment with phenobarbital or skf 525 A. PMID- 4150813 TI - Relationship of serum triglyceride lowering to changes in hepatic composition induced by different classes of drugs. PMID- 4150815 TI - Potentiating effect of cannabidiol on delta9-tetrahydrocannabinol-induced changes in hepatic enzymes. PMID- 4150816 TI - [Effect of beta blockers on muscular vasodilatation by stimulation of the pyramis medullae oblongatae]. PMID- 4150817 TI - [Comparative activities of erythrocytic 17 beta hydroxysteroid dehydrogenase in several mammals in correlation to sex]. PMID- 4150818 TI - Northway virus: a new Bunyamwera group arbovirus from Alaska. PMID- 4150819 TI - Haemodynamic effects of beta blockade in hypertrophic cardiomyopathy using Sectral (acebutolol; M and B 17803A). PMID- 4150821 TI - The secretory antibody response. Anti-DNP antibodies induced by dinitrophenylated type 3 pneumococcus. PMID- 4150820 TI - [The role of succinate in supplying energy for the secretion of hydrochloric acid in the gastric mucosa]. PMID- 4150822 TI - The assay of pneumococcal capsular polysaccharide by immunodiffusion. PMID- 4150823 TI - The effect of emetine on myocardial catecholamine metabolism. PMID- 4150824 TI - Effect of chronic intoxication with (+)-amphetamine on its concentration in liver and brain and on (14C) leucine incorporation into microsomal and cytoplasmic proteins of rat liver. PMID- 4150825 TI - A comparative study of the effect of some centrally acting skeletal muscle relaxants in mice. PMID- 4150826 TI - A study of the interaction of tetracycline with human serum lipoproteins and albumin. PMID- 4150828 TI - Metabolism of heptabarbitone. PMID- 4150827 TI - Metabolism of nealbarbitone. PMID- 4150829 TI - Homogeneity of pharmaceutical dispersed systems. PMID- 4150830 TI - New inhibitor of acetylcholinesterase with preferential activity at nicotinic sites. PMID- 4150831 TI - Interaction of delta9-tetrahydrocannabinol and cannabidiol on intestinal motility in mice. PMID- 4150832 TI - Effect of adrenergic substances on oxygen consumption of rat brain tissue. PMID- 4150833 TI - Effects of phenoxybenzamine, aceperone and clonidine on the level of 3-methoxy-4 hydroxyphenylglycol (MOPEG) in rat brain. PMID- 4150834 TI - Effect of chlorpromazine and some of its metabolites on the dopamine-sensitive adenylate cyclase of rat brain striatum. PMID- 4150835 TI - The absorption of aspirin and paracetamol in patients with achlorhydria. PMID- 4150836 TI - Anti-inflammatory activity of esters of phenylglycine. PMID- 4150838 TI - A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors. PMID- 4150837 TI - The induction of ethanol dependence and the ethanol withdrawal syndrome: the effects of pyrazole. PMID- 4150839 TI - ["Orthopedic assistant"--1-year's experience of the work of a specialized physiotherapist]. PMID- 4150840 TI - [Antibiotic perfusion therapy in osteomyelitis]. PMID- 4150841 TI - [Our experience with the diagnosis and therapy of tumors and tumorous formations of the feet]. PMID- 4150842 TI - [Surgical treatment of acquired extension contracture of the knee joint with Thompson's method]. PMID- 4150843 TI - [Surgical treatment of fixed flatfoot]. PMID- 4150844 TI - [Experience with the treatment of fracture-dislocations of the talus]. PMID- 4150845 TI - [Congenital dislocations of the major joints, multiple bone abnormalities and typical facial structure (Larsen's syndrome)]. PMID- 4150846 TI - [Intervertebral disk calcification in childhood and adolescence]. PMID- 4150847 TI - [Complete open talus dislocation]. PMID- 4150848 TI - [Multiple stab wounds with rare neurologic complications]. PMID- 4150849 TI - [2 cases of proximal tibial epiphysiolysis]. PMID- 4150850 TI - [Hypotonia of the cerebrospinal fluid following cerebrocranial injury]. PMID- 4150851 TI - [Complete isolated dislocation of the talus]. PMID- 4150852 TI - [Comparative study of senile degenerative changes in the hip and shoulder joints]. PMID- 4150853 TI - [Examination of bone fractures with Sr85 isotope]. PMID- 4150854 TI - [Severe complications resulting from late diagnosis of arthritis of the fingers]. PMID- 4150855 TI - Ammonia assimilation in Saccharomyces cerevisiae as mediated by the two glutamate dehydrogenases. Evidence for the gdhA locus being a structural gene for the NADP dependent glutamate dehydrogenase. PMID- 4150856 TI - The effect of the carbon source on ammonium regulation in Aspergillus nidulans. PMID- 4150857 TI - [Monoamine oxidase and respiratory chain enzymatic activity in acute hypoxia]. PMID- 4150858 TI - [Psychopharmacological treatment of the obsessive neuroses]. PMID- 4150859 TI - Action of Burimamide, a histamine antagonist, on acid secretion in vitro. PMID- 4150860 TI - Reduced activation of epidermal phosphorylase in the lesions of psoriasis. PMID- 4150861 TI - [The effect of lithium carbonate on the permeability of the blood-brain barrier and the activity of oxidative enzymes in the brains of rats]. PMID- 4150863 TI - [The effect of oxylidine on several indices of cerebral circulation]. PMID- 4150862 TI - [The effect of anti-adrenergic drugs on the concentration of adenylic nucleotides in rabbit myocardia]. PMID- 4150864 TI - [Comparative assessment of methods of reproducing experimental gastric ulcers]. PMID- 4150865 TI - [Inhibitors of catecholamine biosynthesis (review of the literature)]. PMID- 4150866 TI - [Medicinal substances used for alleviation of cerebral edema-swelling (review of the literature)]. PMID- 4150867 TI - Differentiation of the glycogen body of the chick embryo. Studies on glucose-14 C incorporation, chorioallantoic grafting, histochemistry and electrophoresis. PMID- 4150868 TI - Pharmacological reactivity of isolated ciliary arteries. PMID- 4150870 TI - A simplified MMPI form with reduced reading difficulty level. PMID- 4150876 TI - Bunolol metabolism by human and rat red blood cells and extrahepatic tissues. PMID- 4150878 TI - [Videotape recording in the education of medical assistants]. PMID- 4150877 TI - Alpha adrenergic blocking agents: anti-nociceptive activity and enhancement of morphine-induced analgesia. PMID- 4150879 TI - [Congenital adenomatosis of the adrenals with hyperpigmentation of the skin in a 16-day-old infant]. PMID- 4150880 TI - Diagnosis and treatment of epilepsy: overview and general principles. PMID- 4150881 TI - Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. PMID- 4150882 TI - The role of macrophages, thymus- and bone marrow-derived cells in the graft versus-host reaction. PMID- 4150883 TI - The role of opsonization in antithymocyte globulin-induced suppression of graft versus-host reaction in chick embryos. PMID- 4150884 TI - Immune responses of rats deficient in thymus-derived lymphocytes to strong transplantation antigens (Ag-B). Graft-versus-host activity, allograft rejection, and the factor of immunization. PMID- 4150885 TI - [The nervous system of ctenophores. II. The nervous elements of the mesoglea of beroids and cydippids (author's transl)]. PMID- 4150886 TI - The value of respiratory tract bacteriology in pneumococcal pneumonia among Navajo Indians. PMID- 4150887 TI - Gastrointestinal cancer syndromes. Gastrins, multiple endocrine adenomatosis, and the Zollinger-Ellison syndrome. PMID- 4150888 TI - The binding of (3H)-propylbenzilycholine mustard by longitudinal muscle strips from guinea-pig small intestine. AB - 1 The synthesis of tritium labelled propylbenzilylcholine mustard ([(3)H]-PrBCM; N-2'-chloroethyl-N-[2'', 3''-(3)H(2)] propyl-2-aminoethyl benzilate) is described.2 The uptake by muscle strips was measured and shown to be considerably increased by previous immersion of the muscle in distilled water.3 A considerable part of the uptake is inhibited selectively by atropine, but not by nicotinic antagonists. A number of muscarinic agonists also inhibit uptake and their apparent affinity constants have been determined.4 The uptake by atropine sensitive sites is temperature-insensitive, whereas the other sites are temperature-sensitive. Recovery is highly temperature-sensitive and there is good agreement between recovery of sensitivity to agonists and loss of radioactivity from the muscle. PMID- 4150889 TI - Pharmacology of M & B 18,706, a drug which selectively reduces decerebrate rigidity. AB - 1 (+/-)-10-(3-Dimethylamino-2-methylpropyl)-2-valeroylphenothiazine hydrochloride (M & B 18,706) has been compared with dimethothiazine, chloropromazine, diazepam and baclofen for potency in reducing decerebrate rigidity in the cat and rat and for activity in causing ataxia or sedation.2 When given intravenously M & B 18,706 had seven times the potency of dimethothiazine and one-half the potency of chlorpromazine in reducing the rigidity of the intercollicular decerebrate cat. When administered orally M & B 18,706 and chlorpromazine were equi-potent in reducing rigidity but M & B 18,706 was less effective than chlorpromazine in producing ataxia in this species.3 In the rat, M & B 18,706 had one-quarter the potency of chlorpromazine for reducing decerebrate rigidity but had from 1/20th to 1/200th its potency in tests for sedative or tranquillizing activity.4 M & B 18,706, like dimethothiazine and chlorpromazine, had little effect on the rigidity of ischaemic decerebrate cats and failed to inhibit polysynaptic spinal reflexes.5 M & B 18,706 had intravenous potency comparable to chlorpromazine in reducing the pressor action of noradrenaline in the spinal cat. PMID- 4150890 TI - Transmission to the longitudinal muscle of the guinea-pig vas deferens: The effect of pretreatment with guanethidine. AB - 1 Tissue was taken from guinea-pigs that had been injected with guanethidine (100 mg/kg, i.p.) 24 h before they were killed, and from paired control animals.2 Pretreatment with guanethidine caused a significant, substantial, and sometimes complete reduction of the nerve-mediated contractions of the vas deferens. There were no significant changes in the responses of the ileum to stimulation of cholinergic nerves or of the distal colon to stimulation of intrinsic (non adrenergic) inhibitory nerves. Responses of the vas deferens and ileum to acetylcholine were unchanged, but contractions of the vas deferens elicited by exogenous noradrenaline were enhanced.3 The nerve-mediated contractions of the vas deferens were restored by exposing it to (+)-amphetamine followed by noradrenaline in vitro.4 It is concluded that noradrenaline is the transmitter released from motor nerves to the longitudinal muscle of the guinea-pig vas deferens. Possible explanations for the ineffectiveness of receptor blocking agents in antagonizing transmission are discussed. PMID- 4150892 TI - Separation of normals, neurotics and simulating malingerers on the MPI by means of discriminant function analysis. PMID- 4150891 TI - Effects of lithium ions on electrical activity in sympathetic ganglia of the bullfrog. AB - 1 The mode of action of lithium on electrical activity in the sympathetic ganglia of the bullfrog has been studied by recording extracellular and intracellular potential changes. Changes in nerve conduction and various types of synaptic transmission were studied when sodium ions in the external solution were totally replaced by equimolar concentrations of lithium ions and also when lithium ions were added to the external Ringer solution.2 Nerve conduction and nicotinic transmission in sympathetic ganglia were completely blocked in sodium-free sucrose solution, but were restored when the preparations were transferred to a sodium-free lithium solution.3 In the sodium-free lithium solution, the slow excitatory postsynaptic potential (e.p.s.p.) and muscarinic acetylcholine depolarization were restored while the slow inhibitory postsynaptic potential (i.p.s.p.) and the muscarinic acetylcholine-hyperpolarization were not restored. Furthermore, the early after-discharges were accelerated and the inhibition of after-discharges was eliminated. These results support the hypothetical concept that the slow i.p.s.p. is generated by an activation of the electrogenic sodium pump.4 In the sodium-free lithium solution, restoration of nerve conduction and synaptic transmission were transient phenomena; both conduction and transmission were gradually blocked when preparations were soaked in the solution for long periods. The blockade appeared to be due to membrane depolarization.5 When lithium ions (20 mM) were added to the Ringer solution, nicotinic transmission was depressed. The slow e.p.s.p. was also depressed, but less so than the slow i.p.s.p. The early after-discharge was, however, accelerated; presumably due to the marked depression of the slow i.p.s.p. in this solution.6 Changes in synaptic transmission in Ringer solution containing lithium ions could be explained by membrane depolarization, a reduction of acetylcholine release and a depression of the electrogenic sodium pump.7 All results obtained in the present experiments could be explained by supposing that lithium ions are able to substitute for sodium ions in passive ionic membrane transport dependent on electrochemical energy but not in active ionic membrane transport dependent on metabolic energy. PMID- 4150893 TI - Donor recipient pairing: an attempt to reconcile its theoretical power with its practical utility. PMID- 4150894 TI - [Gastrointestinal complications in periarteritis nodosa]. PMID- 4150895 TI - A comparative study of Excedrin P.M. and placebo. PMID- 4150896 TI - A cross-validation of MMPI scales of aggression on male criminal criterion groups. PMID- 4150897 TI - Accuracy and generalizability of an automated MMPI interpretation system. PMID- 4150898 TI - A comment on Garfield, Prager, and Bergin's evaluation of outcome in psychotherapy. PMID- 4150899 TI - WAIS performance in unincarcerated groups of MMPI-defined sociopaths and normal controls. PMID- 4150900 TI - Phylogeny of immune responsiveness in invertebrates. PMID- 4150901 TI - Do cyclic nucleotides promote the trans-synaptic induction of tyrosine hydroxylase? PMID- 4150902 TI - Control of pineal N-acetylserotonin by a beta adrenergic receptor. PMID- 4150903 TI - Induction of hepatic microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent production of hydrogen peroxide by chronic prior treatment with ethanol. PMID- 4150904 TI - Method of solid tumour evaluation in the immunological experiment. II. A new easy complex method for evaluating resistance. PMID- 4150905 TI - Avian rhabdomyosarcomas induced by Rous sarcoma virus. PMID- 4150906 TI - Some biochemical studies on rats made hyper-reactive by bilateral electrolytic lesions in the anterior hypothalamus. PMID- 4150907 TI - The actions of several psychoactive agents upon the muscarinic mechanisms in the superior cervical ganglion of the cat. PMID- 4150908 TI - [Analysis of variance studies on a soporific]. PMID- 4150909 TI - [Large intravenous doses of cortisone in renal transplantation]. PMID- 4150910 TI - Fatal hemorrhagic disease and shock associated with primary dengue infection on a Pacific island. PMID- 4150912 TI - Infection and transmission of eastern equine encephalomyelitis virus with colonized Culiseta melanura (Coquillett). PMID- 4150911 TI - Venezuelan equine encephalomyelitis in Florida: endemic virus circulation in native rodent populations of Everglades hammocks. PMID- 4150913 TI - Cardiogenic shock: therapeutic implications of altered myocardial energy balance. PMID- 4150915 TI - A quantitative study of the effects of isoproterenol and beta-adrenergic blocking agents in the rat uterus in situ. PMID- 4150914 TI - Batken virus, a new arbovirus isolated from ticks and mosquitoes in Kirghiz S.S.R. PMID- 4150916 TI - The effects of anti-anginal drugs on AV-conduction in normal subjects. PMID- 4150917 TI - A possible relationship between DT diaphorase and the aryl hydrocarbon hydroxylase system. PMID- 4150918 TI - Selenium and hepatic microsomal hemoproteins. PMID- 4150919 TI - Effect of anesthetics on the stability of oxyhemoglobin S. PMID- 4150920 TI - The detection of differential beta-adrenoceptor blockade in the cat. AB - 1. Tachycardia and bronchodilatation were produced by intravenous dimethylphenylpiperazinium iodide (DMPP) in the spinal or pithed cat. Responses other than those involving beta-adrenoceptors were minimized by appropriate blocking agents.2. With intact adrenals, both the tachycardia and bronchodilatation with 10 mug/kg DMPP were equal to those with 1 mug/kg adrenaline.3. After adrenalectomy, tachycardia with 100 mug/kg DMPP was equal to that with 1.5 mug/kg adrenaline, but the bronchodilatation was equal to that with only 0.3 mug/kg. This difference may reflect the relative activity of the sympathetic supply to the organs.4. After adrenalectomy, propranolol was 3 times as effective against bronchodilatation due to DMPP as against tachycardia. Practolol was inactive against bronchodilatation.5. With intact adrenals, propranolol reduced both tachycardia and bronchodilatation due to DMPP equally. Propranolol also antagonized equally both effects of adrenaline in the pithed cat after adrenalectomy.6. In the spinal cat, propranolol caused bradycardia and bronchoconstriction that persisted after adrenalectomy or pithing. It was reduced by pempidine and guanethidine and is attributed to spontaneous adrenergic neuronal activity.7. The Appendix describes a device for cycle-by-cycle spirometry and correction for zero drift of a micromanometer, used in this study for the continuous recording of bronchial resistance. PMID- 4150921 TI - Further studies regarding the structure activity relationships of beta adrenoceptor antagonists. AB - 1. The ortho (M66,527) and para (M66,368) analogues of 1-t-butylamino-3 (methoxyphenoxy)-2-propanol and para substituted tertiary butylphenoxy-1-N isopropylamine-3 propanol-2 oxalate acid (L8429) were tested in dogs for their beta-adrenoceptor blocking activity.2. M66,527, which contains a methoxy group in the ortho position of the benzene ring, was found to be comparable to propranolol in blocking cardiac and peripheral vascular responses to isoprenaline. Like propranolol, M66,527 was more potent on peripheral receptors.3. Transference of the methoxy group to the para position (M66,368) reduced the overall potency; however, this compound was found to be relatively cardioselective in that it was 2 to 3.6 times more active in blocking cardiac responses to isoprenaline.4. The cardioselective properties of the short chain para methoxy substituent were less than those reported for compounds with longer para substitutions (i.e. practolol, para oxprenolol and para alprenolol).5. L8429, with a tertiary butyl group in the para position, was a weak beta-adrenoceptor antagonist without cardioselective properties. A longer, less bulky n-butyl group may provide for a more potent and selective antagonist.6. The results support the view that the size and site of the substituent on the benzene ring may be of importance in determining the cardioselective potency of beta-adrenoceptor antagonists. PMID- 4150922 TI - Glucose-6-phosphate dehydrogenase in the blood of psoriatics, and the effects of methotrexate. PMID- 4150923 TI - Enzymes of glucose metabolism in liver of subjects with adult-onset diabetes. PMID- 4150924 TI - [Hypertension. Diagnosis and therapy in practice]. PMID- 4150925 TI - Multilateral agencies and world population growth. The world plan of action: is China already setting the pace? PMID- 4150926 TI - The role of the World Health Organization in health related aspects of family planning. PMID- 4150927 TI - Altered growth hormone homeostasis during acute bacterial sepsis in the rhesus monkey. PMID- 4150928 TI - Acetylsalicylsalicylic acid: a potentially immunogenic impurity in acetylsalicylic acid. PMID- 4150929 TI - Plasma and cerebrospinal fluid concentrations of pentazocine in patients: assay by mass fragmentography. PMID- 4150930 TI - Functional significance of synthesis of noradrenaline in adrenergic nerves of rat salivary glands. PMID- 4150931 TI - The involvement of dopaminergic systems with the stereotyped behaviour patterns induced by methylphenidate. PMID- 4150932 TI - The correlation between the in vitro and in vivo availability of salicylic acid for membrane transfer from polysorbate 20 solutions. PMID- 4150933 TI - The effect of urea on the solubility of methyl p-hydroxybenzoate in aqueous sodium chloride solutions. PMID- 4150934 TI - An infrared spectrophotometric study of the compaction mechanism of potassium bromide. PMID- 4150935 TI - X-ray analysis of disodium cromoglycate. PMID- 4150936 TI - Some benzhydryl derivatives as central dopamine receptor stimulating agents. PMID- 4150937 TI - Induction of rhythmicity in a normally quiescent smooth muscle. PMID- 4150938 TI - Comparative potencies of dopamine and noradrenaline on the rabbit ear artery. PMID- 4150939 TI - Appearance in cat cerebrospinal fluid of radiolabelled metabolites following intraventricular injection of (3H)choline. PMID- 4150940 TI - Resistance of intestinal alpha-adrenoceptors to cold storage. PMID- 4150941 TI - Effect of 2,5-dimethoxy-4-methylamphetamine on heart and smooth muscle contraction. PMID- 4150942 TI - Non-specific actions of dihydroxylated tryptamines in the central nervous system of the rat. PMID- 4150943 TI - The dependence of imipramine-induced sedation upon central 5-hydroxytryptamine like activity in the frog. PMID- 4150944 TI - A possible interaction of quipazine with central dopamine structures. PMID- 4150945 TI - Daily susceptibility variations to the morphine-induced hyperactivity of rats. PMID- 4150946 TI - Stability of rolitetracycline in aqueous solution. PMID- 4150947 TI - The polarographic and spectral behaviour of some 1,4-benzodiazepine metabolites: application to differentiation of mixtures. PMID- 4150948 TI - Congenitally uncoiled epididymis in a cryptorchid testicle. PMID- 4150949 TI - Abdominal musculature deficiency syndrome prune belly. PMID- 4150950 TI - Development of tolerance in rats to the hypothermic effects of D-amphetamine and apomorphine. PMID- 4150951 TI - Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism. PMID- 4150952 TI - Coronary vasomotor responses to cardiac sympathetic nerve stimulation after adrenergic beta-receptor in dogs. PMID- 4150953 TI - Editorial: Symposium on dialysis. PMID- 4150954 TI - Acebutolol in cardiac arrhythmias. PMID- 4150955 TI - Prune belly syndrome. PMID- 4150957 TI - [NADP-reductive enzymes in the rabbit adrenals in experimental hypercholesteremia]. PMID- 4150956 TI - [Tyrosine aminotransferase activity in the rat liver and thyroid gland after the administration of glutaminic acid under normal conditions and in hypoxia]. PMID- 4150958 TI - How learning conditions in early childhood--including mass media--relate to aggression in late adolescence. PMID- 4150959 TI - The action of nitrous acid on C-teichoic acid (C-substance) from the walls of Diplococcus pneumoniae. AB - 1. C-teichoic acid (C-substance) from the walls of Diplococcus pneumoniae contained free amino groups accessible to attack by nitrous acid. Treatment with nitrous acid, followed by reduction with borohydride and hydrolysis with acid, gave ribitol, glucitol and their respective phosphates. 2. Hydrolysis of the polymer with alkali followed by treatment of products with nitrous acid yielded glucose. 3. When alkali hydrolysis was followed by treatment with a phosphomonoesterase, nitrous acid degradation of C-substance yielded glucose and a disaccharide identified as 2-O-(N-acetylgalactosaminyl)-d-ribitol. 4. A partial structure for C-teichoic acid was deduced in which the order of the constituent residues and the position of phosphodiester linkages were established. PMID- 4150960 TI - Natural abundance 13C nuclear magnetic resonance spectra of nicotinamide adenine dinucleotide and related nucleotides. PMID- 4150961 TI - [Approach to the study of the activating mechanisms from PGF2a during the embryonal-implantation time (author's transl)]. PMID- 4150962 TI - Production, estimation, and reproduction of time intervals during inhalation of a general anesthetic in man. PMID- 4150963 TI - Effects of some hypocholesterolemic agents on hepatic ulrastructure and microbody enzymes. PMID- 4150964 TI - [Reducing of lesions induced by hyperbaric oxygenation (HO) in the rat using various anti-adrenergic therapy]. PMID- 4150965 TI - Effects of beta adrenergic blockade on plasma catecholamines in exercise. PMID- 4150966 TI - [Treatment of migraine and kindred headaches]. PMID- 4150967 TI - [Clinical observations on Sandomigren in treatment of headaches]. PMID- 4150968 TI - [Aspects of psychopharmacological treatment of personality disorders]. PMID- 4150969 TI - [Mental disorders in patients with chronic cardiorespiratory insufficiency]. PMID- 4150970 TI - [Therapy of pathological cryptorchism. Short communication]. PMID- 4150972 TI - [Treatment of undescended testis]. PMID- 4150973 TI - [Sodium fluoride therapy of osteoporosis from the rheumatologists viewpoint. Extract of the 8th Workshop of the Research Society for Diseases of the Locomotor System, May 1973, Baden-Vienna]. PMID- 4150971 TI - Human marrow transplantation--current status. PMID- 4150975 TI - Scanning electron microscopy of the sensory surface of the tentacles of sea anemones and corals. PMID- 4150974 TI - [Results of the International Symposium on Sweetening Agents]. PMID- 4150976 TI - Stimulation of enzyme synthesis and inhibition of DNA synthesis and growth rate by cyclic AMP derivatives in cultured hepatoma cells. PMID- 4150977 TI - Inhibition of amino acid transaminases by L-cycloserine. PMID- 4150978 TI - Food and light as separate entrainment signals for rat liver enzymes. PMID- 4150979 TI - Estrogen-induced uterine enzymes in the control of estradiol action. PMID- 4150980 TI - Marrow transplantation for aplastic anemia and acute leukemia. PMID- 4150981 TI - [Complete repair of tetralogy of Fallot before 5 years of age. Apropos of 31 cases]. PMID- 4150982 TI - [Conduction disorders induced by piperazine; clinical and experimental study]. PMID- 4150984 TI - Editorial: WFMH is alive and well and living in Jamaica. PMID- 4150983 TI - Modification of the responsiveness of F1 hybrid rats to lymphocytes from parental strain rats. PMID- 4150985 TI - Allylglycine, and inhibitor of the uptake of L-leucine and L-proline in rat brain slices. PMID- 4150986 TI - Interaction of apomorphine, neuroleptics and stimulants with alpha-methyl-m tyramine, a false dopaminergic transmitter. PMID- 4150987 TI - [Membrane potential in the chromatophores of Rhodospirillum rubrum conditioned by a transhydrogenase reaction]. PMID- 4150988 TI - [The importance of gamma-glutamyltranspeptidase activity screening (author's transl)]. PMID- 4150989 TI - The purification of Portuguese man-of-war nematocyst toxins by gel diffusion. PMID- 4150990 TI - The role of dihydropyrimidinase in the metabolism of some hydantoin and succinimide drugs. PMID- 4150991 TI - Urinary metabolites of N-methyl-alpha-methyl-alpha-phenysuccinimide (methsuximide) in the dog. PMID- 4150992 TI - The metabolism of betahistine in the rat. PMID- 4150993 TI - Metabolism of the herbicide methozole (2-(3,4-dichlorophenyl)-4-methyl-1,2,4 oxadiazolidine-3,5-dione) in rats. PMID- 4150994 TI - Studies on the metabolism and pharmacology of alpha-((2 pyridylamino)methyl)benzyl alcohol hydrochloride (phenyramidol hydrochloride) in rodents. PMID- 4150995 TI - Dihydrodigoxin: a common metabolite of digoxin in man. PMID- 4150996 TI - Identification and activity of the hydroxy metabolite that accumulates in the plasma of humans intoxicated with glutethimide. PMID- 4150997 TI - Hepatic uptake, metabolism, and biliary excretion of 7,12-dimethylbenzanthracene in the rat. PMID- 4150998 TI - Effect of the hypolipidemic drug nafenopin (2-methyl-2-(p-(1,2,3,4-tetrahydro-1 naphthyl)phenoxy)propionic acid; TPIA; SU-13,437), on the hepatic disposition of foreign compounds in the rat. PMID- 4150999 TI - Studies on the physiologic disposition and activity of phenylpropanolamines in the mouse. PMID- 4151000 TI - The aniline hydroxylase and nitroreductase activities of partially purified cytochromes P-450 and P-420, and cytochrome b5 solubilized from rabbit hepatic microsomes. PMID- 4151001 TI - Present status of underwater medicine. Review of some challenging problems. PMID- 4151002 TI - Cold exposure: effects on hepatic tryptophan oxygenase and tyrosine aminotransferase, plasma tryptophan and tyrosine, and brain monoamines. PMID- 4151003 TI - [A study of central nicotine-sensitive cholinoreceptors by introducing bis quaternary ammonium compounds into the lateral cerebral ventricles]. PMID- 4151004 TI - [A comparative assessment of the effectiveness of using benzohexonium, vinylin and preparation "Spedian-2M" in the treatment of reserpine ulcers of the stomach]. PMID- 4151005 TI - [The mechanism of barbiturate induction of enzyme systems metabolizing medicinal compounds (review of the literature)]. PMID- 4151006 TI - [The effect of adreno- and sympathoblocking substances on ophthalmotonus (review of the literature)]. PMID- 4151007 TI - Pharmacological study of antihistaminic principle(s) in the Rana tigrina tissues. PMID- 4151008 TI - Studies on local anaesthetic and antiarrhythmic actions of 1-isopropylamino-3-(4 indanoxy)-2-propanol HCI (USVC-6524), a new beta-adrenoceptor antagonist. PMID- 4151009 TI - Effect of ten beta-adrenoceptor blocking agents on spontaneous motility and pentobarbital-induced anaesthesia in mice. PMID- 4151010 TI - Histochemical studies of the skin in recurrent erysipelas. PMID- 4151011 TI - Needle method of testicular biopsy. PMID- 4151012 TI - Autoradiographic study on the recirculating lymphocytes in rats undergoing graft versus-host reaction. PMID- 4151013 TI - Reduced output of thoracic duct cells in rats affected by graft-versus-host reaction. PMID- 4151014 TI - [A comparison of different methods of determining glutamine synthetase activity in yeasts]. PMID- 4151015 TI - Field studies on the feeding habits of mosquitoes in the highveld region of South Africa. PMID- 4151017 TI - [Conversational psychotherapy in 73 psychoneurotic clients with alternating psychotherapists without selective choice]. PMID- 4151016 TI - [Dyshormonal disorders during development of experimental testicular tumors]. PMID- 4151018 TI - Effect of pyrazole on rat liver catalase. PMID- 4151019 TI - [Time expended by assistants of specialist health physicians in industrial hygiene for services to employees of machine building and light industry]. PMID- 4151020 TI - [From the history of feldsher training in the Kherson district]. PMID- 4151021 TI - [Feldsher's role in the control of tuberculosis in a rural population]. PMID- 4151025 TI - Proceedings: 85. Relationship between metals and enzymes in canine pancreatic juice. PMID- 4151026 TI - [Proceedings: 189. Beta-action of isoprenaline on the smooth muscle of guinea-pig taenia coli (author's transl)]. PMID- 4151027 TI - Proceedings: SGOT and CPK isoenzymes in clinical medicine. PMID- 4151028 TI - Proceedings: Gamma-glutamyl transpeptidase elevation in patients receiving enzyme inducing anticonvulsant drugs. PMID- 4151029 TI - Proceedings: Advances in clinical enzymology. PMID- 4151030 TI - [Proceedings: Behavior of some serum enzymes during a course of immunosuppressive therapy in chronic hepatitis]. PMID- 4151031 TI - [Proceedings: Correlation between gamma-glutamyl transpeptidase serum levels and liver damage due to alcohol]. PMID- 4151032 TI - [Proceedings: Severity index as an expression of a battery of examinations for evaluation of chronic liver diseases]. PMID- 4151033 TI - [Proceedings: Enzymatic and chemico-clinical correlations in hepatitis of the "porphyria cutanea tarda"]. PMID- 4151034 TI - [Proceedings: Gamma-glutamyl transpeptidase, leucine aminopeptidase and alkaline phosphatase in the serum and urine in the diagnosis of neoplasms]. PMID- 4151035 TI - Proceedings: Specific determination of glucose-6-phosphate dehydrogenase in erythrocytes using the LKB 8600: extraction procedures, stability studies, and reference values calculated per mean erythrocyte. PMID- 4151036 TI - Sir Rickard Christophera: the first 100 years. A biographical note. PMID- 4151037 TI - A review of studies on the immunization against the pathogenic protozoan diseases of man. PMID- 4151038 TI - Parasitic protozoa of the blood of rodents. II. Haemogregarines, malaria parasites and piroplasms of rodents: an annotated checklist and host index. PMID- 4151039 TI - The occurrence of intracellular rickettsia-like organisms in the tsetse flies, Glossina morsitans, G. fuscipes, G. brevipalpis and G. pallidipes. PMID- 4151040 TI - Amino acid analyses of haemolymph of Glossina morsitans morsitans (Westwood). PMID- 4151041 TI - Tick-host relationships. 3. The effect of photoperiodic pre-conditioning on the circadian rhythm of "drop-off" of engorged pre-imaginal stages of the tick Hyalomma excavatum (Koch, 1844) from the gerbil--Meriones tristrami. PMID- 4151042 TI - Indirect assessment of myocardial oxygen consumption in the evaluation of mechanisms and therapy of angina pectoris. PMID- 4151043 TI - Medical screening of patients with coronary artery disease. Criteria for entrance into exercise conditioning programs. PMID- 4151044 TI - Comparison of media for detection of fungi on spacecraft. AB - Five media, including Trypticase soy agar (TSA; BBL) pour plates, spread plates of TSA, Mycophil agar with chloromycetin, Mycophil agar with chloromycetin and Actidione, and cornmeal agar with chloromycetin were quantitatively and qualitatively compared for the detection of fungi on spacecraft. Cornmeal agar with chloromycetin yielded the highest number of fungal colonies, although not always significantly higher than Mycophil agar with chloromycetin or TSA spread plates. Cornmeal agar with chloromycetin also gave the best qualitative representation of fungi on the spacecraft, recovering 68% of the genera found from all media. This medium yielded 10 times the number of fungal colonies and 3 times the number of genera found on TSA pour plates as currently used for spacecraft assay. PMID- 4151045 TI - The effect of certain tranquilisers, chlorpromazine metabolites and diethyldithiocarbamate on tissue amphetamine levels in the rat. PMID- 4151046 TI - Interactions of quazodine with cardiotoxic doses of ouabain in the anesthetized dog. PMID- 4151047 TI - Pulmonary and systemic circulatory effects of midodrine, a new sympathomimetic, and its metabolite, ST 1059. PMID- 4151048 TI - Antiarrhythmic and general cardiovascular activity of the N,N-dimethylquaternary ammonium derivative of bunolol. PMID- 4151049 TI - Interaction of phenothiazine derivatives with human ceruloplasmin. PMID- 4151050 TI - Studies on enzymatic dealkylation of D-lysergic acid diethylamide (LSD). PMID- 4151051 TI - Microsomal epoxidation of cis-stilbene: decrease in epoxidase activity related to lipid peroxidation. PMID- 4151052 TI - Electroencephalographic investigations during evaluation of the antiepileptic agent sulthiame. PMID- 4151053 TI - Role of the sympathetic innervation of the pacinian corpuscle. AB - An investigation was made into the nature of the role played by the noradrenergic innervation of the pacinian corpuscle. Corpuscles of the cat mesentery and mesocolon were used in all experiments. Blockade of noradrenergic beta receptors by dichloroisoproterenol and interference with norepinephrine release by reserpine are each capable of reversibly blocking mechanoelectric transduction by the pacinian corpuscle. The monoamine oxidase inhibitors iproniazid and phenelzine are capable of protecting the transducer from the blocking effects of reserpine. It is concluded that the presence of norepinephrine, as maintained by sympathetic tonus, is required for the afferent nerve terminal of the pacinian corpuscle to be mechanosensitive. PMID- 4151054 TI - [Analysis of the mechanism of the vasodilative action of droperidol]. PMID- 4151056 TI - Traumatized teeth of children. Emergency and intermediate restorative treatment. PMID- 4151055 TI - [Filiform changes of the corneal epithelium (author's transl)]. PMID- 4151057 TI - [Gold solders and soldered joints. I. Mechanical properties]. PMID- 4151058 TI - [Gold solders and soldered joints. II. Corrosion resistance]. PMID- 4151059 TI - Quantitative alterations in the ecology of the oropharyngeal microflora subsequent to tonsillectomy and adenoidectomy. PMID- 4151060 TI - Glucagon and the insulin: glucagon ratio in severe trauma. PMID- 4151061 TI - [Clinical investigations as to the value of the bank bone-graft (Kiel) (author's transl)]. PMID- 4151062 TI - Editorial: Hypoglycaemia and personality. PMID- 4151063 TI - Development of filarial parasites in mosquitos in north-east Tanzania. AB - Natural populations of 6 species of mosquito-Anopheles tenebrosus, Taeniorynchus (Mansonioides) africanus, Taeniorynchus (Mansonioides) uniformis, Anopheles coustani, Anopheles ziemanni, and Anopheles pharoensis-were examined for filarial parasites. Infective stages of Dirofilaria immitis were found in the first 3 of these species, which are therefore considered vectors. Laboratory studies to see whether or not any of the 6 could potentially transmit Wucheria bancrofti showed only A. tenebrosus to be capable of producing the infective stage. PMID- 4151064 TI - [Hygienic evaluation of certain forms of lecture work]. PMID- 4151065 TI - [Method of determining the rate of information processing (using tables)]. PMID- 4151066 TI - Bacterial growth in vivo. An important determinant of the pulmonary clearance of Diplococcus pneumoniae in rats. AB - Lung clearance of Diplococcus pneumoniae was markedly reduced in rats with acute hemorrhagic pulmonary edema produced by instillation of hydrochloric acid. Bacterial clearance was enhanced in both control and acid-instilled animals by pretreatment with a bacteriostatic antibiotic, tetracycline, 30 mg/kg. From these data the contributions of bacterial multiplication and bacterial elimination to net lung bacterial clearance were estimated. In control animals the constant for exponential bacterial elimination was -1.4283 (fractional clearance = 76% per h), and the doubling time for the pneumococcus was 170 min. In acid-instilled rats the elimination constant was -0.5336 (fractional clearance = 41% per h), and the doubling time of the pneumococcus was 47 min, approximating the doubling time of 42 min observed with pneumococci grown in broth. These results indicate that, in the case of pneumococci, both bacterial elimination and bacterial growth contribute to lung bacterial clearance in normal animals as well as animals with damaged lungs. In the present study changes in both parameters were required to explain the observed results in acid-instilled animals. The pulmonary pathogenicity of some bacterial species may be determined by their capacity for growth in the lung, since infection of the lung occurs when bacterial multiplication exceeds the rate of elimination of viable organisms. PMID- 4151068 TI - [Alcohol and society]. PMID- 4151067 TI - Complete restoration of bursa-dependent immune system after transplantation of semiallogeneic stem cells into immunodeficient chicks. AB - For transplantation of semiallogeneic bursal stem cells into cyclophosphamide treated 3-day old chicks, two lines of chickens homozygous at the major histocompatibility locus and their F(1) hybrids were used in reciprocal combinations. The semiallogeneic transplantations resulted in a complete restoration of antibody formation to sheep red blood cells (SRBC) and Brucella, of microscopic morphology of bursa fabricii, and of germinal center formation in the spleen. In contrast, allogeneic bursal stem cells were not effective in restoring secondary response to SRBC and germinal center formation, while they were able to reconstitute anti-Brucella responses and bursal morphology. These findings indicate an effective cooperation of donor and host cells leading to a complete restoration of the bursa-dependent lymphoid system, when the donor and recipient share at least one haplotype determining the major histocompatibility antigen complex. PMID- 4151069 TI - [Cryptorchism (diagnosis, clinical picture, and therapy)]. PMID- 4151070 TI - To the members of the International Commission on Trichinellosis (ICT). PMID- 4151071 TI - Spermatozoan vesicle loss during penetration of the female gonangium in the hydroid. Campanularia flexuosa. PMID- 4151072 TI - Functional units in the labellar chemosensory hairs of the mosquito Culiseta inornata (Williston). PMID- 4151073 TI - New curare-like agents. PMID- 4151074 TI - The sorption of benzocaine from aqueous solution by nylon 6 powder. PMID- 4151075 TI - Butobarbitone metabolism in man: identification of 3'-ketobutobarbitone. PMID- 4151076 TI - In vivo estimation of tyrosine hydroxylation in the dopaminergic terminals of the rat neostriatum. PMID- 4151077 TI - Role of the central autonomic nervous system in the hypotension and bradycardia induced by (-)-delta 9-trans-tetrahydrocannabinol. PMID- 4151078 TI - Bioassay of vasopressin on the rabbit isolated urinary bladder. PMID- 4151079 TI - An assay for phenylephrine applicable to stability studies. PMID- 4151080 TI - Infrared spectroscopy using attenuated total reflection. PMID- 4151081 TI - Metabolism of chlorphentermine and phentermine in man to yield hydroxylamino, C nitroso- and nitro-compounds. PMID- 4151082 TI - A technique for repeated blood sampling with transfusion in the conscious rat. PMID- 4151083 TI - Effect of chloroquine on histamine-induced bronchial asthma in the guinea-pig. PMID- 4151084 TI - Paradoxical thermoregulatory behaviour in rats induced by (plus)-amphetamine: blockade by alpha-adrenoceptor or dopamine receptor blocking agents. PMID- 4151085 TI - Letter: Do adrenergic fibres have muscarinic inhibitory receptors? PMID- 4151086 TI - Letter: The calculation of the tensile strength of tablets. PMID- 4151087 TI - The effects of burimamide on gastric acid secretion and gastric mucosal blood flow in the anaesthetized cat. PMID- 4151088 TI - [Psychosomatic specificity and cornary heart diseases: trial of the verification of Dunbar's theory by means of MMPI]. PMID- 4151089 TI - [SWO (systematic work organization) of a physician's assistant]. PMID- 4151090 TI - [Ergometric and hemodynamic studies under administration of the beta adrenolytic agent Bunitrolol]. PMID- 4151091 TI - Influence of age on ortho-hydroxyphenylacetic acid excretion in phenylketonuria and its genetic variants. PMID- 4151092 TI - Agranulocytosis associated with sulphasalazine therapy. PMID- 4151093 TI - Effect of phenobarbital administration on liver and plasma gamma-glutamyl transpeptidase: clinical and experimental investigations. PMID- 4151094 TI - Effect of calcitonin on gastric and pancreatic secretion and peptic ulcer formation in cats. PMID- 4151095 TI - Familial occurrence of Noonan syndrome. PMID- 4151096 TI - Efficacy of a "mixed bacterial vaccine" in prophylaxis of acute respiratory infections: possible role of interferon. PMID- 4151097 TI - Aspects of inorganic nitrogen assimilation in yeasts. PMID- 4151098 TI - Metabolic effects of acetaldehyde in the intact rat brain cortex and its subcellular fractions. PMID- 4151099 TI - The bronchodilator activity of AY-22093, a prostanoic acid derivative. PMID- 4151100 TI - Blockade of cardiac histamine receptors by promethazine. PMID- 4151101 TI - The effects of pretreatment of mice with norethindrone on the metabolism of 14C imipramine by the liver microsomal drug-metabolizing enzymes. PMID- 4151102 TI - Anesthetic experience with total hip replacement. PMID- 4151103 TI - In quest of emesis: fact, fable, and fancy. PMID- 4151104 TI - Hospital management of acute iron ingestion. PMID- 4151105 TI - Methemoglobin reductase deficiency in a dog. PMID- 4151106 TI - Reactions between certain strains of pneumococci and Fc of IgG. PMID- 4151107 TI - Regulation of the antibody response to type 3 pneumococcal polysaccharide. IV. Role of suppressor T cells in the development of low-dose paralysis. PMID- 4151108 TI - Interaction of C-reactive protein complexes with the complement system. I. Consumption of human complement associated with the reaction of C-reactive protein with pneumococcal C-polysaccharide and with the choline phosphatides, lecithin and sphingomyelin. PMID- 4151109 TI - Physical and immunologic properties of pneumococcal capsular polysaccharide produced during human infection. PMID- 4151110 TI - An autopsy case of Behcet's syndrome associated with pulmonary arteritis and tuberculosis. PMID- 4151111 TI - Studies on iron loading of rat liver lysosomes. Effects on the liver and distribution and fate of iron. PMID- 4151112 TI - The personal doctor--a luxury or a necessity? PMID- 4151113 TI - A glimpse of medicine in China. PMID- 4151114 TI - An arteritis with special reference to polymyalgia arteritica. PMID- 4151115 TI - Systemic granulomatous reaction to salicylazosulfapyridine (Azulfidine) in a patient with Crohn's disease. PMID- 4151116 TI - Damage to teeth during the administration of general anaesthesia. PMID- 4151117 TI - Enzymatic production of urocanic acid by Achromobacter liquidum. AB - To develop an efficient method for the production of urocanic acid, optimal conditions for the production of microbial L-histidine ammonia lyase and for the conversion of L-histidine to urocanic acid by this enzyme were studied. A number of microorganisms were screened to test their ability to form and accumulate urocanic acid from L-histidine. Achromobacter liquidum was selected as the best organism. With this organism, enzyme activity as high as 2.0 units/ml could be produced by a shaking culture at 30 C in a medium containing glucose, urea, potassium phosphate, L-histidine, yeast extract, peptone, and inorganic salts. Appropriate addition of a surface-active agent to the reaction mixture shortened the time required for the conversion. A large amount of L-histidine was converted stoichiometrically to urocanic acid in 48 h at 40 C. Accumulated urocanic acid was readily isolated in pure form by ordinary procedures with isoelectric precipitation. Yields of isolated urocanic acid of over 92% from L-histidine were easily attainable. When the culture of Achromobacter liquidum was added to DL histidine, D-histidine and urocanic acid were simultaneously obtained in high yields. PMID- 4151119 TI - 7th European Conference on Microcirculation. International conference, Aberdeen 1972. I. Methodology in microcirculation. PMID- 4151118 TI - Mathematical estimation on the level of microbial contamination on spacecraft surfaces by volumetric air sampling. AB - Microbiological sampling methods presently used for enumeration of microorganisms on spacecraft surfaces require contact with easily damaged components. Estimation of viable particles on surfaces using air sampling methods in conjunction with a mathematical model would be desirable. Parameters necessary for the mathematical model are the effect of angled surfaces on viable particle collection and the number of viable cells per viable particle. Deposition of viable particles on angled surfaces closely followed a cosine function, and the number of viable cells per viable particle was consistent with a Poisson distribution. Other parameters considered by the mathematical model included deposition rate and fractional removal per unit time. A close nonlinear correlation between volumetric air sampling and airborne fallout on surfaces was established with all fallout data points falling within the 95% confidence limits as determined by the mathematical model. PMID- 4151120 TI - [Practical medical treatment of essential hypertension]. PMID- 4151121 TI - [Antibiotic therapy and chemotherapy of enterogenic urticaria]. PMID- 4151122 TI - [Beta-adrenergic blocking agents and ventilatory function. Clinical aspects]. PMID- 4151123 TI - Lichen planus. A case presentation. PMID- 4151124 TI - [Antasten--a fatal poisoning case]. PMID- 4151125 TI - [Life events and health]. PMID- 4151126 TI - [Clinical study on treatment with nicergoline in a group of patients with hemiplegia in a post-acute phase]. PMID- 4151127 TI - Neurohumoral control of blood coagulation: participation of the adrenal glands. PMID- 4151128 TI - Neurohumoral control of blood coagulation: adrenergic stimulation and spleen in the control of factor VIII plasma level. PMID- 4151129 TI - [Industrial foot injuries at the Minsk Motor Plants. Its causes and prophylaxis]. PMID- 4151130 TI - [Why is there such uncertainty about the effectiveness of anti-angina drugs?]. PMID- 4151131 TI - [Pharmacologic basis and application of catecholamines in the treatment of shock]. PMID- 4151132 TI - Bilaterally cryptorchid stallion with female karyotype. PMID- 4151134 TI - [Letter: Therapeutic possibilities in chronic papulous urticaria]. PMID- 4151133 TI - Comparative enzymatic development in chick embryonic brain areas. PMID- 4151135 TI - We must write next chapter of anti-substitution saga. PMID- 4151136 TI - Forearm replantation. A case report of a two-year follow-up. PMID- 4151137 TI - Hemofiltration for Schistosomiasis japonicum. PMID- 4151138 TI - Drugs in the management of learning and behavior disorders in school children. PMID- 4151139 TI - Angiosarcoma of the liver. PMID- 4151140 TI - "Snap, crackle, and pop". PMID- 4151141 TI - The view box. PMID- 4151143 TI - Simple fluoroscopic studies for upper airway problems. PMID- 4151142 TI - EKG of the month. PMID- 4151144 TI - Surgical grand rounds. Parietal cell vagotomy. PMID- 4151145 TI - Prescribing physical therapy. PMID- 4151146 TI - Treatment of children with burns. PMID- 4151147 TI - Editorial: Medicine in trouble. PMID- 4151148 TI - Simultaneous measurement of eight foreign gases in blood by gas chromatography. PMID- 4151149 TI - Treatment of anxiety neurosis by alpha and beta adrenergic blocking agents. PMID- 4151150 TI - Physician's assistant program: development and current status at WSU. PMID- 4151152 TI - A specialty for associate-degree nursing program graduates: increasing neophyte competency and confidence. PMID- 4151151 TI - Jack of all trades--master of none. PMID- 4151153 TI - Expectations of the associate-degree graduate: a director of nursing's point of view. PMID- 4151154 TI - Associate degree: education for what? PMID- 4151155 TI - Editorial: Issues in associate-degree education in nursing. PMID- 4151156 TI - Associate-degree graduates: generalists or specialists? PMID- 4151157 TI - For everything there is a time. PMID- 4151158 TI - Pharmacology of the central nervous system. PMID- 4151159 TI - The autonomic nervous system. PMID- 4151160 TI - Regional physiology of the nervous system. PMID- 4151161 TI - [Clinical studies of chronic bromine poisoning]. PMID- 4151162 TI - [Correlation between caries and nutrition in the Tolbukhin and Plovidiv districts of Bulgaria]. PMID- 4151163 TI - [Professional representatives must have education]. PMID- 4151164 TI - [Cancer nursing, a conference for nurses]. PMID- 4151165 TI - [From Morjarvs a combined interest in the organizational presidency of the Swedish Student Nurses Association]. PMID- 4151166 TI - [Epidemiologic study of tooth loss using questionnaires]. PMID- 4151168 TI - Lymphocyte and polymorphonuclear enzymes in stress. IV. Changes associated with an acute bacterial infection with Diplococcus pneumoniae. PMID- 4151167 TI - Organic solvent extraction of liver microsomal lipid. I. The requirement of lipid for 3,4-benzpyrene hydroxylase. PMID- 4151169 TI - Studies in occupational dentistry. II. Dental hazards affecting battery formation workers. PMID- 4151170 TI - Effect of beta-adrenergic blocking compounds on tissue catecholamine levels. PMID- 4151171 TI - Bronchodilator effects of sympathomimetic amines given singly and in combination. PMID- 4151172 TI - Rapid purification of glucose 6-phosphate dehydrogenase from human erythrocytes by means of affinity chromatography. PMID- 4151173 TI - Hormonal regulation of tyrosine transaminase synthesis in isolated, rat liver perfused with synthetic medium. PMID- 4151174 TI - Studies on the regulation of glutathione level in rat liver. PMID- 4151175 TI - The regulation of glutamine synthesis in the food yeast Candida utilis: the purification and subunit structure of glutamine synthetase and aspects of enzyme deactivation. PMID- 4151176 TI - The colony-forming cell in the normal and leukemia human host: responses to streptovaricin and rifamycin SV. PMID- 4151177 TI - Effects of an epoxide hydrase inhibitor on in vivo binding of polycyclic hydrocarbons to DNA and on skin carcinogenesis. PMID- 4151178 TI - Effect of pyridoxine deficiency on tyrosine transaminase activity and growth of four Morris hepatomas. PMID- 4151179 TI - Letter: Untreatable pain: the three-time losers. PMID- 4151180 TI - Elevated immunoglobulin E in infantile polyarteritis nodosa. PMID- 4151181 TI - Identification of S-carboxymethyl-thiopyruvate as the product of oxidative deamination of S-carboxymethyl-cysteine. PMID- 4151183 TI - Pneumococcal meningitis in mother and neonate. PMID- 4151182 TI - The oxidative desaturation of unsaturated fatty acids in animals. PMID- 4151184 TI - Letter: Cryptorchidism in siblings. PMID- 4151185 TI - [Behavior of gamma-glutamyl-transpeptidase (gamma-GT) in some diseases of the liver]. PMID- 4151186 TI - The second-class doctor and the medical assistant in South Africa. PMID- 4151187 TI - Analysis of neurochemical mechanisms of one form of intra-species behavior. PMID- 4151188 TI - [Identification of unrecognizable cadavers by forensic dentistry. An experience report]. PMID- 4151189 TI - [Investigations on the UV-photometric detection of recent ingestion of therapeutic and suicidal doses of carbromal (Adalin) in urine. II. Detection of bromides in chemical toxicology (author's transl)]. PMID- 4151190 TI - Aryl hydrocarcon hydroxylase and tyrosine aminotransferase activities in somatic cell hybrids derived from hepatoma tissue culture HTC (rat) cells and 3T3 (mouse) benzo(a)pyrene-resistant cells. PMID- 4151191 TI - Enzymatic reduction of D-biotin-d-sulfoxide with cell-free extracts of Escherichia coli. PMID- 4151193 TI - Low temperature electron paramagnetic resonance studies on iron-sulfur centers in cardiac NADH dehydrogenase. PMID- 4151192 TI - Oxidative phosphorylation and respiratory control in lysolecithin treated electron transport particles. PMID- 4151194 TI - The role of messenger RNA in tyrosine aminotransferase superinduction: effects of camptothecin on hepatoma cells in culture. PMID- 4151195 TI - NADPH-dependent reductase solubilized from microsomes by peroxidation and its activity. PMID- 4151196 TI - Tyrosine hydroxylase activity: regional and subcellular distribution in the brain. PMID- 4151197 TI - [Ultrastructural identification of monoamine-containing nerve endings in the guinea-pig median eminence (author's transl)]. PMID- 4151198 TI - Effect of metiamide, a histamine H2-receptor antagonist, on mucosal blood flow and serum gastrin level. PMID- 4151199 TI - [Value of transtracheal aspiration in bronchopulmonary infections in adults]. PMID- 4151200 TI - Adrenoceptors and salt and water movement in epithelia. PMID- 4151201 TI - Foot and mouth disease O1-antibody levels in Egyptian cattle. PMID- 4151202 TI - Characterization of papovavirus-and picornavirus-like particles in permanent pig kidney cell lines. PMID- 4151203 TI - [Cause-effect relationships in infectious diseases (author's transl)]. PMID- 4151204 TI - Conversion of phage types of S. typhi-murium due to different R-plasmids. PMID- 4151205 TI - Phage typing of S. typhi murium in the Netherlands. 1. The phage typing system. PMID- 4151206 TI - Phage typing of S. typhi murium in the Netherlands. 2. Frequency distributions of S. typhi murium phage types in the Netherlands during 1971 and 1972. PMID- 4151207 TI - [Investigations on the effect of crystal violet on salmonella R mutants. 1. Communication: binding experiments (author's transl)]. PMID- 4151208 TI - [The effects of human-and animal-pathogenic coli strains on the isolated intestine of rabbit (author's transl)]. PMID- 4151209 TI - The action of phospholipase A on the common Enterobacteriaceae antigen of the Kunin-type. PMID- 4151210 TI - [Lack of reproduction in certain Enterobacter aerogenes strains producing fraction 2 Aerocines]. PMID- 4151211 TI - [Classification of butyric-acid-forming anaerobians among the genus Bacteroides on the basis of their lipid metabolism (author's transl)]. PMID- 4151212 TI - [Actinomyces eriksonii Georg, Robertstad, Brinkman and Hicklin 1965 identical with Bifidobacterium adolescentis Reuter 1963 (author's transl)]. PMID- 4151213 TI - [Investigations of the serological relationship between Actinomyces israelii and Corynebacterium acnes (author's transl)]. PMID- 4151214 TI - Release of the dipicolinic acid (DPA) from spores of Bacillus stearothermophilus, B. megaterium and B. anthracis in presence of dyes. PMID- 4151215 TI - Growth and extracellular lipids of certain pathogenic fungi in presence of different concentrations of amino acids. PMID- 4151216 TI - [Mechanism of stimulating action of prostaglandin F2alpha on the contractile activity of the uterus]. PMID- 4151217 TI - Heat inactivation and determination of serum gamma-glutamyltranspeptidase as a profile in identification of human alkaline phosphatase. PMID- 4151218 TI - Letter: Polyarteritis after influenza vaccination. PMID- 4151219 TI - Cellular energy metabolism during fetal development. V. Fatty acid synthesis by the developing heart. PMID- 4151220 TI - Induction of tyrosine aminotransferase by triamcinolone during rat liver development in vitro. PMID- 4151221 TI - Circulatory support with intravenous microdrip drug therapy. PMID- 4151222 TI - The physician assistant: one solution to the health care crisis. PMID- 4151223 TI - Studies on the eyes of catfishes with special reference to the tapetum lucidum. PMID- 4151224 TI - Reappearance of specific colour patterns after nerve regeneration in Octopus. PMID- 4151225 TI - Studies on the structure and function of the mammalian testis. IV. Steroid metabolism in vitro by isolated interstitium and seminiferous tubules of rat testis after heat sterilization. PMID- 4151226 TI - The arrangement of myosin on the surface of paramyosin filaments in the white adductor muscle of Crassostrea angulata. PMID- 4151227 TI - A D-periodic narrow filament in collagen. PMID- 4151228 TI - The occurrence of carnitine and glycerylphosphorylcholine in the octopus spermatophore. PMID- 4151229 TI - Bile acids. XLI. Hepatic microsomal 12 alpha-hydroxylation of allochenodeoxycholate to allocholate. PMID- 4151230 TI - Gamma glutamyl transpeptidase in chronic obstructive pulmonary disease. PMID- 4151231 TI - Diagnosis of alcoholism. Factors of drinking, background and current conditions in alcoholics. PMID- 4151233 TI - Graft-versus-host disease in rats after donor treatment with cyclophosphamide and spleen cells of host origin. PMID- 4151232 TI - Ethanol and acetaldehyde effects on metabolism and binding of biogenic amines. PMID- 4151234 TI - Thymus dependency of periarteritis nodosa in DOCA and salt treated mice. PMID- 4151235 TI - An investigation of the ionic calcium assay based on the jellyfish protein aequorin. PMID- 4151236 TI - Reversal of verapamil-, dichloroisoproterenol-, and propranolol-induced cardiac failure by histamine. PMID- 4151237 TI - Guinea-pig atrial and pulmonary beta-adrenoceptors. PMID- 4151238 TI - Strabismus. PMID- 4151239 TI - [Participation of photosystems I and II in the process of photophosphorylation]. PMID- 4151241 TI - Advances in human growth hormone research. PMID- 4151240 TI - High molecular weight isoenzymes of alkaline phosphatase in human serum. Demonstration by cellulose acetate electrophoresis and physico-chemical characterization. PMID- 4151242 TI - [Changes in the volume of blood outflow from the liver in certain reflex and humoral actions on the blood circulation]. PMID- 4151243 TI - Blood levels and antibacterial activity of sera in patients treated with cyclacillin. PMID- 4151245 TI - Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. II. Effect of serum and insulin. PMID- 4151244 TI - Plasma renin activity after the use of a new beta-adrenergic blocking agent (I.C.I. 66,032). PMID- 4151246 TI - Autoradiographic studies of pyridine nucleotide metabolism in human culture cells. PMID- 4151247 TI - Excitatory and inhibitory control of inherent contractions in the sea anemone Calliactis parasitica. PMID- 4151248 TI - The central effects of the beta-adrenergic blocking agent INPEA. PMID- 4151249 TI - Hypothermic effect of alpha-sympathomimetic agents and their antagonism by adrenergic and cholinergic blocking drugs. PMID- 4151250 TI - A comparison of the locomotor stimulant properties of amantadine and l- and d amphetamine in mice. PMID- 4151251 TI - Induction of adrenal tyrosine hydroxylase in organ culture. PMID- 4151252 TI - Frequency-force relationship on isolated rat and guinea pig atria. Effects of cholinergic and adrenergic receptor antagonists. PMID- 4151253 TI - Enzyme activities in vitamin B6-deficient, normal and tumor-bearing animals: effect of hydrocortisone. PMID- 4151254 TI - Inhibition of growth of mouse mammary carcinoma by streptovaricin. PMID- 4151255 TI - Hypothalamic monoamine levels and gonadotrophin secretion following deafferentation of the medial basal hypothalamus. PMID- 4151256 TI - Input to releasing factor cells. PMID- 4151257 TI - Enzyme activities and morphometry in skeletal muscle of middle-aged men after training. PMID- 4151258 TI - The use of drugs in psychiatric interviews: some interpretations based on controlled experiments. PMID- 4151259 TI - Laboratory studies for every medicated outpatient: are they really necessary? PMID- 4151260 TI - Letter: Side effects of chlorpromazine and piperacetazine. PMID- 4151261 TI - Letter: Caveats on diagnosing assassins. PMID- 4151262 TI - Primary acts of energy conservation in the functional membrane of photosynthesis. PMID- 4151263 TI - Structure of the mitochondrial electron transport system. PMID- 4151264 TI - Assembly of inner membrane complexes. PMID- 4151265 TI - Redox state and chain folding in cytochrome c. PMID- 4151266 TI - The adoptive transfer of first-set allograft responses by recirculating small lymphocytes in the rat. PMID- 4151267 TI - Beta-adrenergic receptors: stereospecificity and lack of affinity for catechols. PMID- 4151268 TI - Inhibition of messenger RNA accumulation but not translation in ultraviolet irradiated hepatoma cells. PMID- 4151270 TI - Action of bamethan on performance time in mice. PMID- 4151269 TI - A simple apparatus for studying the release of neurotransmitters from synaptosomes. PMID- 4151271 TI - [Regional blood flow in the brain. II. Effects of central stimulants, convalsants and a dissociative anesthetic on regional blood flow in the brain]. PMID- 4151272 TI - Rotary lawn mower injuries. PMID- 4151273 TI - Current status of blood alcohol methods. PMID- 4151275 TI - China's barefoot doctors. PMID- 4151274 TI - The identification of non-barbiturate hypnotics from biological specimens. PMID- 4151276 TI - A comparative study of Minnesota Multiphasic Personality Inventory (MMPI) scores of four apparently different black populations. PMID- 4151277 TI - Editorial: A prognosis for pediatrics. PMID- 4151278 TI - [Optimal time of surgical treatment of cryptorchism]. PMID- 4151279 TI - [Free skin plasty in traumatic lesions of the foot]. PMID- 4151280 TI - Clinical evaluation of Bametan. PMID- 4151281 TI - Immunological facilitation, a broadening of the concept of the enhancement phenomenon. PMID- 4151282 TI - Cellular immunology and the pathogenesis of graft versus host reactions. PMID- 4151283 TI - Marine sterols from some gorgonians. PMID- 4151284 TI - [Tavegyl in treatment of allergic skin diseases]. PMID- 4151285 TI - Synthesis of N-oxides with a hepatic microsomal drug oxidase insolubilized on artificial matrices. PMID- 4151286 TI - Hydroxy-L-proline as a substrate for hog kidney D-amino acid oxidase. PMID- 4151287 TI - Sounder payment programs could foster improvements. PMID- 4151288 TI - An educational view of the CHA. PMID- 4151289 TI - Health manpower and advanced education. PMID- 4151290 TI - Do nurses belong in hospital schools? PMID- 4151291 TI - OR instrument counts: a manual for standardization. PMID- 4151292 TI - CHA must stay in health education. PMID- 4151293 TI - A problem-solving package for building committees. PMID- 4151294 TI - Negligence and error in judgment. PMID- 4151295 TI - [Pharmacologic characteristics of pyrroxan]. PMID- 4151296 TI - [The effect of psychostimulators on ATPase activity stimulated by Na and K ions in rat brain microsomal fractions]. PMID- 4151297 TI - [The effect of M- and N-cholinolytics on several arterial blood indices of acid base equilibirium]. PMID- 4151299 TI - [Polyglandular syndrome, type I]. PMID- 4151298 TI - [The antipsychotic action of neuroleptics and basal ganglia function]. PMID- 4151300 TI - [Tranquilizers in pregnancy]. PMID- 4151301 TI - Neuroleptanesthesia, dissociative anesthesia, and hemorrhage. PMID- 4151302 TI - Management of general anesthesia during hemorrhage. PMID- 4151303 TI - The effect of adrenergic and cholinergic agents and their blockers upon ureteral activity. PMID- 4151304 TI - The treatment of delirium tremens: controversy in the literature. PMID- 4151306 TI - Dihydrofolate reductase from a methotrexate-resistant Escherichia coli. PMID- 4151305 TI - Regulation of alanine dehydrogenase in Bacillus (licheniformis). AB - Cell extracts of Bacillus licheniformis were found to contain nicotinamide adenine dinucleotide (NAD)-dependent l-alanine dehydrogenase (ADH) (l-alanine: NAD oxidoreductase, EC 1.4.1.1). High specific activities (3.5 to 6.0 IU/mg of protein) were found in extracts of cells throughout growth cycles only when l alanine served as the primary source of carbon or carbon and nitrogen. Specific activities were minimal (0.02 to 0.04 IU/mg of protein) during growth on glucose, but increased at least sevenfold during the first 5 h of postlogarithmic-phase metabolism. Addition of 10 mM glucose to cultures during logarithmic-phase growth on l-alanine resulted in a rapid decrease in enzyme activity. Addition of 20 mM l alanine to cells near the completion of log-phase growth on glucose resulted in a 20-fold increase in ADH specific activity during less than one cell generation. Extracts of postlogarithmic-phase cells cultured on glucose, malate, l-glutamate, or Casamino Acids contained intermediate levels of ADH activity. The enzyme was partially purified from crude extracts of B. licheniformis, and apparent kinetic constants were estimated. A role for ADH in the catabolism of l-alanine to pyruvate during vegetative growth on l-alanine and during sporulation of cells cultured on glucose is proposed on the basis of these experimental results. PMID- 4151307 TI - Evidence that apo-reduced nicotinamide adenine dinucleotide dehydrogenase and apo electron-transferring flavoprotein from Peptostreptococcus elsdenii are identical. PMID- 4151308 TI - The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. I. Initial velocity, substrate and product inhibition, and isotope exchange studies. PMID- 4151309 TI - The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. II. Dead-end and multiple inhibition studies. PMID- 4151311 TI - Host-feeding patterns of Florida mosquitoes. IV. Deinocerites. PMID- 4151310 TI - [Current trends in application of induced hypothermia as an adjunct to open heart surgery--with special reference to the theme at the 8th Nippon Teitaion Kenkyukai]. PMID- 4151312 TI - Symposium on reproduction of arthropods of medical and veterinary importance. V. Reproduction in Diptera of medical importance with special reference to mosquitoes. PMID- 4151314 TI - Protocols for monitoring physician-extenders. PMID- 4151313 TI - Induction of drug-metabolizing enzymes and aryl hydrocarbon hydroxylase by microscope immersion oil. PMID- 4151315 TI - Frequency of eating and dental caries prevalence. PMID- 4151316 TI - Deficits in instrumental responding after 6-hydroxydopamine lesions of the nigro neostriatal dopaminergic projection. PMID- 4151317 TI - [Succinate dehydrogenase, NAD-H2- and NADPH-H2-diaphorase activity in a herpetic infection of a cell culture]. PMID- 4151318 TI - [Study of the biological properties of the Olyka virus isolated from mosquitoes (Culicidae) in the western Ukraine]. PMID- 4151319 TI - [Biological determination of urine catecholamines as screening method for pheochromocytoma--with special reference to drug influence on catecholamine metabolism]. PMID- 4151320 TI - [Pharmacokinetic studies in man with a beta-sympathomimetic drug used as aerosol]. PMID- 4151321 TI - Density-gradient centrifugation of mouse liver mitochondria H2O-D20 gradients. PMID- 4151322 TI - [Experimental and clinical studies on increase of gammaglutamyltranspeptidase activity in serum in hepathobiliary diseases]. PMID- 4151323 TI - Simultaneous increases of the adenylate energy charge and the rate of glycogen synthesis in nitrogen-starved Escherichia coli W4597(K). PMID- 4151324 TI - Microsomal electron transport. II. Reduced nicotinamide adenine dinucleotide- cytochrome b5 reductase and cytochrome P-450 as electron carriers in microsomal NADH-peroxidase activity. PMID- 4151325 TI - Nitrate reductase from Chlorella fusca. Reversible inactivation by thiols and by sulfite. PMID- 4151326 TI - NAD malic enzyme in leaves with C-pathway photosynthesis and its role in C4 acid decarboxylation. PMID- 4151327 TI - 25-Hydroxycholecalciferol-1-hydroxylase: a specific requirement for NADPH and a hemoprotein component in chick kidney mitochondria. PMID- 4151328 TI - Editorial: Selectivity in beta-adrenergic responses: clinical implications. PMID- 4151329 TI - Late bronchial obstructive reaction to experimental inhalation of house dust extract. PMID- 4151330 TI - Carbohydrate metabolism in Acanthamoeba castellanii. II. Carbon dioxide fixation reactions. PMID- 4151331 TI - Carbohydrases with unusual specificities. 3. A hydrolase splitting p-nitrophenyl 2-deoxy-2-benzamido-beta-D-glucopyranoside--distribution in marine invertebrates and certain mushrooms. PMID- 4151332 TI - The effect of parenteral indoramin on peripheral blood flow in patients with Raynaud's disease or atherosclerosis associated with intermittent claudication. PMID- 4151333 TI - [Letter: Tardive dyskinesia, a little-known extrapyramidal syndrome due to therapy with neuroleptics]. PMID- 4151334 TI - High-pressure liquid chromatographic determination of adrenergic and antihistaminic compounds in pharmaceutical preparations. PMID- 4151335 TI - [Growth in the dark and the NADH-oxidase activity of Rhodopseudomonas palustris]. PMID- 4151336 TI - [Effect of some coronary active drugs on angina threshold, ECG reaction and myocardial metabolism during frequency load in coronary disease patients]. PMID- 4151337 TI - [Atypical dose-frequency relation as characteristic of a beta receptor blocker]. PMID- 4151338 TI - [Action mechanism of oxyfedrin (ildamen) in animal experiment and in man]. PMID- 4151339 TI - Cell-mediated cytotoxicity, allograft rejection, and tumor immunity. PMID- 4151340 TI - The effect of chlorpromazine and antihistamines on human blood platelets in vitro and in vivo. PMID- 4151341 TI - CoAS-Sglutathione and GSSG reductases from rat liver. Two disulfide oxidoreductase activities in one protein entity. PMID- 4151342 TI - GMP reductase in Artemia salina. PMID- 4151343 TI - Mechanism of enzyme action. VII. Kinetic analysis of the reaction of D-amino-acid oxidase with D-arginine. PMID- 4151344 TI - Styrylpyrone biosynthesis in Polyporus hispidus. II. Enzymic hydroxylation of p coumaric acid and bis-noryangonin. PMID- 4151345 TI - Mammalian fatty acid synthetase. I. Purification and properties of human liver complex. PMID- 4151346 TI - Mechanism of regulation of the malic enzyme from Fusarium. PMID- 4151347 TI - Analogy and homology of the dehydrogenases of Oomycetes. I. Regulation of glutamic dehydrogenases and isozyme patterns. PMID- 4151348 TI - Analogy and homology of dehydrogenases of the Oomycetes. 3. Isoenzyme patterns of malic and isocitric dehydrogenases. PMID- 4151349 TI - [Effect of intense mental work during the day and evening hours on the urinary excretion of catecholamines]. PMID- 4151350 TI - [Hemodynamic reactions to an increase in the perfusion pressure in the carotid sinuses]. PMID- 4151351 TI - Study of relationship between antihistaminic, anticholinergic and central depressant properties of various antihistaminics. PMID- 4151352 TI - [An unusual cause of Adams-Stokes syndrome]. PMID- 4151353 TI - [Colitis--newer aspects upon ulcerative colitis and Crohn's disease in the colon]. PMID- 4151354 TI - [Role of granulocytes in the defense against infection]. PMID- 4151355 TI - [Advances in the diagnosis of cholelithiasis (author's transl)]. PMID- 4151356 TI - [Hyperimmunoglobulinemia M in diseases with an autoaggressive mechanism]. PMID- 4151357 TI - The evaluation of physician's assistants in radiology. PMID- 4151358 TI - Experiences of an Army nurse in developing care plans for outpatients with chronic illnesses. PMID- 4151359 TI - Measures of skewness and kurtosis of distributions of blood and liver constituents of rats (Rattus norvegicus) at two environmental temperatures. PMID- 4151360 TI - Comparative responses of Peromyscus (white-footed mice) to estradiol benzoate. PMID- 4151361 TI - The isolation and partial characterization of membranes from dystrophic and normal muscle. PMID- 4151362 TI - Action potentials from a glycerol perfused frog gastrocnemius: a new approach to an old problem. PMID- 4151363 TI - Taste effectiveness of anomers of sugars and glycosides as revealed from hamster taste responses. PMID- 4151364 TI - Directional instability and oscillation of the acid-base transport system of the tortoise urinary bladder, Damonia subtrijuga. PMID- 4151365 TI - The effects of temperature, anoxia and sensory stimulation on the heart rate of unrestrained crabs. PMID- 4151366 TI - Experimental shigellosis and intestinal malabsorption in the mouse. PMID- 4151367 TI - Effect of metabolic inhibitors and chelating agents on 59Fe uptake by the placental tissues of the rat, Rattus norvegicus. PMID- 4151368 TI - Active amino acid and sugar transport by a unicellular blue-green alga. PMID- 4151369 TI - Gastric acid secretion and ulcerogenesis in histamine-treated guinea pigs. PMID- 4151370 TI - Induction by gonadal hormones of hepatic lipogenic enzyme activity in immature pullets. PMID- 4151372 TI - Chemical, histochemical, and histopathological studies on corals. Porites spp., parasitized by trematode metacercariae. PMID- 4151371 TI - Proceedings: Some histochemical changes in immature mouse ovaries after gonadotrophin treatment. PMID- 4151373 TI - A baculovirus from the mosquito Wyeomyia smithii. PMID- 4151374 TI - Parathelohania legeri infecting Psorophora ciliata. PMID- 4151375 TI - Emergency medical care--the physician's responsibility. PMID- 4151376 TI - Growth and sporulation characteristics of Bacillus megaterium under different conditions of nutrient limitation. PMID- 4151377 TI - Relation between structure of sulphonamides and inhibition of H2-pteroate synthesis in Escherichia coli. PMID- 4151378 TI - Competitive interaction of preservative mixtures with cetomacrogol. PMID- 4151379 TI - Adsorption of atropine and hyoscine on magnesium trisilicate. PMID- 4151380 TI - A comparison of the effects of chronic administration of ethanol and acetaldehyde to mice: evidence for a role of acetaldehyde in ethanol dependence. PMID- 4151382 TI - Metabolism of isoprenaline in the intestine. PMID- 4151381 TI - Effect of L-dopa in 54Mn incorporation by tissues. PMID- 4151383 TI - Isolation of cantharidin from Cyaneolytta sapphirina. PMID- 4151384 TI - Prostaglandins in rat tissues. PMID- 4151385 TI - Effect of O-methylation on the acceleration of efflux of noradrenaline produced by phenethylamine derivatives. PMID- 4151386 TI - Effect of several dopaminergic drugs and trihexyphenidyl on cholinergic parameters in the rat striatum. PMID- 4151387 TI - Dose-dependent potentiation or inhibition by Ro4-4602 of 5-HTP hyperthermia in rabbits. PMID- 4151388 TI - Effect of morphine and chlorpromazine on apomorphine-induced stereotyped behavior. PMID- 4151389 TI - A refined procedure for determining pA2 values. PMID- 4151390 TI - D-Glucaric acid as an index of hepatic enzyme induction by anticonvulsant drugs in man. PMID- 4151391 TI - The micellar weights of the series dioctyl-to-didodecyl phosphatidylcholine. PMID- 4151392 TI - Tryptamine antagonists and punished behavior. PMID- 4151393 TI - Evidence for a critical period for postnatal elevation of brain tyrosine hydroxylase activity resulting from reserpine administration during embryonic development. PMID- 4151394 TI - Cardiovascular and bronchomotor responses to selective beta adrenergic receptor agonists in the anesthetized dog. PMID- 4151395 TI - Accumulation of amines in the isolated perfused rabbit lung. PMID- 4151396 TI - [Education of assistant physicians--time for planning]. PMID- 4151397 TI - The origin of the integrative systems: a change in view derived from research on coelenterates and sponges. PMID- 4151398 TI - [Comparative clinical and cytogenetical studies of 2 forms of male hypergonadotropic hypogonadism (Klinefelter's syndrome and bilateral cryptorchism)]. PMID- 4151399 TI - Effects of clonidine and some alpha-adrenoreceptor blocking agents on avoidance conditioned reflexes in rats: their interactions and antagonism by atropine. PMID- 4151400 TI - The influence of centrophenoxine and ephedrine on the hyporeactivity of the autonomic centres in patients with cerebral infarction. PMID- 4151401 TI - The antiulcer and autonomic pharmacology of pyridyl-2-thioacetamide (CMN 131). PMID- 4151402 TI - Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes. PMID- 4151403 TI - Immunochemical evidence for the participation of cytochrome b5 in the NADH synergism of the NADPH-dependent mono-oxidase system of hepatic microsomes. PMID- 4151404 TI - XY-XYY mosaicism associated with major genital defects. PMID- 4151405 TI - Methyprylon overdose: interpretation of serum drug concentrations. PMID- 4151406 TI - Testosterone in normal, cryptorchid and castrated male horses. PMID- 4151407 TI - Biopsy and the testicular artery of the horse. PMID- 4151408 TI - The bacterial nitrate reductases. Solubilization, purification and properties of the enzyme A of Escherichia coli K 12. PMID- 4151409 TI - Enzymatic and chemical synthesis of 3-sulfinopropionic acid, an analog of succinic acid. PMID- 4151410 TI - Delta4-3 beta-hydroxysteroid dehydrogenase activity in rat liver. Intracellular distribution and sex dependency. PMID- 4151411 TI - Steroid-synthesizing cellular sites in amphibian ovary. A histochemical study. PMID- 4151412 TI - Induced changes in neurosecretory activity of adult female Schistocerca gregaria in relation to feeding. PMID- 4151413 TI - Venezuelan equine encephalitis epidemic in Texas, 1971. PMID- 4151414 TI - Trade-offs and conflicts in evaluation of health system alternatives: methodology for analysis. PMID- 4151415 TI - Biochemical correlation of oncogenesis with ontogenesis. PMID- 4151417 TI - Comparison of the predictive validity of two measures of psychotherapy prognosis. PMID- 4151416 TI - Phenytoin intoxication induced by sulthiame in epileptic patients. AB - Routine estimation of serum phenytoin levels in patients newly admitted to a Special Centre for Epilepsy showed that 40% of those receiving sulthiame in addition to phenytoin had levels in the toxic range. Four long-stay patients became drug intoxicated when sulthiame treatment was started. Sulthiame appears to inhibit the hepatic hydroxylation of phenytoin. PMID- 4151418 TI - Noradrenergic mediation of traumatic spinal cord autodestruction. PMID- 4151420 TI - The organization and implementation of advanced medical training. PMID- 4151419 TI - Benzodiazepines for supplementing steroid anesthesia. PMID- 4151421 TI - [Oxidation of reduced nicotinamide-adeninedinucleotide in Pseudomonas aeruginosa adaptation to hexane]. PMID- 4151422 TI - [Kinetic properties of the glutamine synthetase of Candida tropicalis fodder yeasts in Mg2+- and Mn2+-activated glutamine synthesis reactions]. PMID- 4151423 TI - Foreign medical graduates and the medical underground. PMID- 4151424 TI - The effects of substrates of mixed function oxidase on ethanol oxidation in rat liver microsomes. PMID- 4151425 TI - Amphetamine and thermoregulation: studies in the unrestrained and curarized rat. PMID- 4151426 TI - Feeding elicited by alpha and beta adrenoceptor agonists in sheep and cattle. PMID- 4151428 TI - Psychosexual dynamics of patients undergoing mammary augmentation. PMID- 4151427 TI - Relationship between prostagandin E1, polyphloretin phosphate and alpha and beta adrenoceptor-bound feeding loci in the hypothalamus of sheep. PMID- 4151429 TI - Personality disorder and the international classification of diseases. PMID- 4151430 TI - Medical Research Council Neurochemical Pharmacology Unit. PMID- 4151431 TI - Enzymatic reduction of disulfide bonds in fibrin-ogen by the thioredoxin system. I. Identification of reduced bonds and studies on reoxidation process. PMID- 4151432 TI - Correlation of immunological function with splenic histopathology during the preclinical stages of host-versus-graft syndrome in parent-F1 mouse chimeral. PMID- 4151433 TI - Letter: The retention of graft-versus-host-reactive host lymphocytes in a vascularized spleen graft. PMID- 4151434 TI - [Kinetic characteristics of NADP-dependent isocitrate dehydrogenases]. PMID- 4151435 TI - [Effect of "carboxyline" on the restoration of free nucleotides in the duck liver]. PMID- 4151436 TI - [Nitrogen metabolic enzyme activity in the rat brain after the action of oxygen under increased pressure]. PMID- 4151437 TI - [Effect of pyruvate dehydrogenase coenzymes on the oxygen and NAD+ absorption of rat liver mitochondria]. PMID- 4151438 TI - [Principles of autoimmunity]. PMID- 4151439 TI - [Function of renal homotransplants under intravenous administration of steroids]. PMID- 4151440 TI - Biotransformation of fluroxene in man. PMID- 4151441 TI - Connective tissue disorders in otolaryngology. PMID- 4151442 TI - Inhibition of adrenergic function in the treatment of hypertension. PMID- 4151443 TI - Drug combinations as rational antihypertensive therapy. PMID- 4151444 TI - [Rubinstein-Taybi syndrome. Apropos of 2 new cases]. PMID- 4151445 TI - [Effect of iridectomy or iridotomy on the evolution of transfixed grafts]. PMID- 4151446 TI - Conference studies relationship between quality of care and medical training. PMID- 4151447 TI - Fatty acid synthesis de novo in human adipose tissue. PMID- 4151448 TI - [Testosterone biosynthesis in spontaneous dystopic rat testes with genetic descensus disorder]. PMID- 4151449 TI - Leukemia induction in C3H mice following their inoculation with normal AKR lymphoid cells. PMID- 4151450 TI - Immunodepression as a factor during 3-methylcholanthrene carcinogenesis and subsequent tumour growth in mice. PMID- 4151451 TI - 5-Keto-D-fructose: formation and utilization in the course of D-fructose as similation by Gluconabacter cerinus. AB - The accumulation of 5-keto-d-fructose (5KF) by Gluconobacter cerinus grown on d fructose in unbuffered medium was shown to be optimal at pH 4.0 after cell growth ceased. During the exponential phase of growth or at neutral pH after the onset of the stationary phase, 5KF production continued but did not accumulate because of its rapid reutilization by reduction to d-fructose. The extent of isotope incorporation into C5 of ribonucleic acid ribose when cells were grown in the presence of specifically labeled d-glucose and d-fructose clearly indicated that (i) the hexose monophosphate oxidative pathway is the predominant metabolic route for carbohydrate assimilation and (ii) extensive randomization of label between C1 and C6 of d-fructose occurred prior to its conversion into pentose. It is suggested that the cyclic oxidation and reduction through the symmetrical 5KF molecule, which accounts for the observed randomization of isotope in d-fructose, provides the cells with an effective mechanism for the regeneration of nicotinamide adenine dinucleotide phosphate during the period of intensive growth. PMID- 4151452 TI - In situ activity of enzymes on polyacrylamide gels of a deoxyribonucleic acid membrane fraction extracted from pneumococci. AB - A deoxyribonucleic acid (DNA)-membrane fraction extracted from Diplococcus pneumoniae was subjected to polyacrylamide gel electrophoresis after treatment with 0.16% sodium dodecyl sulfate. At least two DNA polymerase activities were detected by in situ assays with appropriate substrates, templates, and inhibitors, including a co-polymer of deoxyadenylic and thymidylic acid and N ethylmaleimide. This activity coincided with a fraction in the gel containing 7.5, 9.4, and 24%, respectively of the DNA, phospholipid, and protein present in the DNA-membrane fraction before electrophoresis and sodium dodecyl sulfate treatment. Assays with minced gels showed that several nuclease activities, deoxyribonucleotide kinase activity, and DNA ligase activity also coincided with this fraction. However, ribonucleoside diphosphate reductase activity did not. These results demonstrate that a complex of enzymes involved in DNA replication is firmly bound to the DNA-membrane fraction in pneumococci. PMID- 4151453 TI - Purification and properties of a diacetyl reductase from Escherichia coli. AB - A reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent reductase with the ability to reduce diacetyl has been isolated from Escherichia coli and has been purified 800-fold to near homogeneity. The product of the reduction of diacetyl was shown to be acetoin. The enzyme proved to catalyze the oxidation of NADPH in the presence of both uncharged alpha- and beta-dicarbonyl compounds. Even monocarbonyl compounds showed slight activity with the enzyme. On the basis of its substrate specificity, it is suggested that the enzyme functions as a diacetyl reductase. In contrast to other diacetyl reductases, the one reported here is specific for NADPH and does not possess acetoin reductase activity. The pH optimum of this enzyme was found to be between 6 and 7. The maximal velocity for the NADPH-dependent reduction of diacetyl was determined to be 9.5 mumol per min per mg of protein and the K(m) values for diacetyl and NADPH were found to be 4.44 mM and 0.02 mM, respectively. The molecular weight was estimated by gel filtration on Sephadex G-100 to be approximately 10,000. PMID- 4151454 TI - Synergy among responding lymphoid cells in the one-way mixed lymphocyte reaction. Interaction between two types of thymus-dependent cells. AB - The present studies have shown that two subpopulations of thymus-dependent lymphocytes may act synergistically in the mixed lymphocyte reaction (MLR) in the mouse. One subpopulation was well represented in the young adult thymus and the other in lymph nodes. For optimum synergy, both populations must be allogeneic to the stimulator cells. Pretreatment of either population with mitomycin-C abolished synergy. Anti-theta serum abolished both MLR responding and synergizing activities of lymphoid cells. The two thymus-dependent subpopulations were both present in the spleen, and displayed different migratory patterns when injected into irradiated mice: one population went to spleens of the irradiated mice, the other to lymph nodes. The effects of anti-thymocyte serum on the MLR and upon synergy were assessed. While minor differences exist and are herein described, our overall results strongly suggest that in our experiments with synergy in MLR, we may be dealing with the same T(1)- and T(2)-cell subpopulations described by Cantor and Asofsky and coworkers (1, 2, 4, 5, 14) as displaying synergy in the graft-vs.-host reaction. PMID- 4151455 TI - Genetic control of the antibody response to type 3 pneumococcal polysaccharide in mice. II. Relationship between IgM immunoglobulin levels and the ability to give an IgM antibody response. AB - Serum IgM immunoglobulin levels and antibody responses to an optimally immunogenic dose of Type III pneumococcal polysaccharide (SSS-III) were assessed for F(1), F(2), and backcross progeny derived from crosses between high responding BALB/cAnN (B) and low responding CBA/HN (C) mice. The results obtained confirmed our original hypothesis, namely, that a major component, present on the X chromosome, governs the ability to respond to SSS-III in a decisive manner. Although all low responding C mice had low IgM levels, both intermediate and high responders had high IgM levels of the same magnitude. Treatment with bacterial lipopolysaccharides (LPS) resulted in a significant increase in the IgM levels of low responding C mice. While the IgM levels attained were similar to those of high responding B mice, not given LPS, no antibody specific for LPS appeared to be produced. These findings suggest that C mice are unable to make an IgM antibody response to SSS-III and other polysaccharide antigens, despite the fact that they possess the capacity to synthesize normal amounts of IgM immunoglobulin. PMID- 4151456 TI - 8-(Omega-aminoalkylamino)quinolines as potential prophylactic antimalarials. PMID- 4151457 TI - 10-Alkyl- and 10-aminoalkyl-2,2'-bis(trifluoromethyl)-3,10'-biphenothiazines. PMID- 4151458 TI - Stimulation of serotonin N-acetyltransferase in pineal organ culture by drugs. PMID- 4151460 TI - Inhibition of the biochemical and morphological maturation of adrenergic neurons by nicotinic receptor blockade. PMID- 4151459 TI - Effect of L-DOPA on brain concentration of dopamine and homovanillic acid in rats after chronic manganese chloride administration. PMID- 4151461 TI - Liquid chromatography in pharmaceutical analysis: determination of cough-cold mixtures. PMID- 4151462 TI - Health manpower: trends and issues. PMID- 4151463 TI - Clonal cell lines from the rat central nervous system. PMID- 4151464 TI - Temperature immutability of adenyl cyclase-coupled beta adrenergic receptors. PMID- 4151465 TI - The pineal gland: a neurochemical transducer. PMID- 4151466 TI - Peptide regulation of bursting pacemaker activity in a molluscan neurosecretory cell. AB - Vasopressin and related peptides (10(-9) to 10(-6) molar) induced bursting pacemaker potential activity and altered the current-voltage relations of the membrane in a specific molluscan neurosecretory cell. These effects long outlasted the period of application of the peptides. Sensitivity of the cell to these peptides was primarily localized on the axon hillock region. The observed effects do not resemble conductance changes evoked by conventional neurotransmitters, but rather suggest a membrane regulatory role for these peptides, and thus may be indicative of a new form of information transfer in the nervous system. PMID- 4151467 TI - Immunotherapy in leukemia. Experimental and clinical approaches. PMID- 4151468 TI - [Caries statistical cross-sectional studies in children and adolescents]. PMID- 4151469 TI - Effect of lithium on deiodinating activity of various rat tissues in vitro. PMID- 4151470 TI - The pathophysiologic panorama of myocardial ischemia and infarction. PMID- 4151471 TI - Molecular and catalytic properties of transglutaminases. PMID- 4151472 TI - Clinical evaluation of superior oblique function. PMID- 4151473 TI - Classification and treatment of superior oblique palsy. PMID- 4151474 TI - Superior oblique surgery. PMID- 4151475 TI - The function of the superior oblique muscle in man. A correlation of clinical observation with experimental findings. PMID- 4151476 TI - [Effect of minimal hepatectomy on catalase and peroxisomal oxidase activity in rat liver]. PMID- 4151477 TI - Human 6-phosphogluconate dehydrogenase. Purification of the erythrocyte enzyme and the influence of ions and NADPH on its activity. PMID- 4151478 TI - Nitrite reductase from Achromobacter fischeri: molecular weight and subunit structure. PMID- 4151479 TI - Effects of dehydroepiandrosterone and its conjugates upon the activity of glucose 6-phosphate dehydrogenase. V. Inhibition of glucose-6-phosphate dehydrogenase in human placenta. PMID- 4151480 TI - Xanthogranulomatous pyelonephritis. PMID- 4151481 TI - The non-visualizing gallbladder. PMID- 4151482 TI - Surgical grand rounds: cecal volvulus. PMID- 4151483 TI - EKG of the month. PMID- 4151484 TI - Editorial: Unnecessary surgery. PMID- 4151485 TI - The view box. PMID- 4151486 TI - Studies on stabilization of the oxidative phosphorylation system. 3. The effects of substrates and ATP on sensitivity of various energy-linked functions of submitochondrial particles to phospholipase a from Crotalus terrificus venom. PMID- 4151487 TI - Activity of guinea pig liver transglutaminase toward ester analogs of amide substrates. PMID- 4151488 TI - Mitochondrial cytochrome p450. A component of chick kidney 25 hydrocholecalciferol-1alpha-hydroxylase. PMID- 4151489 TI - Dihydrodipicolinic acid reductase. PMID- 4151490 TI - [Studies on soldering of Au-Pt and Au-Pd-Cu-Ag alloys (author's transl)]. PMID- 4151491 TI - Molecular orbital studies on the mechanism of drug-receptor interaction. 1. Adrenergic drugs. Conformation and reactivity of isoproterenol and 1-(p nitrophenyl)-2-isopropylaminoethanol. PMID- 4151492 TI - Beta-adrenoceptor studies. 1. In vitro beta-adrenergic blocking, antiarrhythmic, and local anesthetic activities of a new series of aromatic bis(2-hydroxy-3 isopropylaminopropyl) ethers. PMID- 4151493 TI - Derivatives of 3,4-dihydrocarbostyril as beta-adrenergic blocking agents. PMID- 4151495 TI - Editorial: The quality of life in later years. PMID- 4151494 TI - Studies on beta-lactams. 35. Antibacterial activity of monocyclic beta-lactams. PMID- 4151496 TI - [Tentative explanation of the etiology of reversed T wave in electrocardiograms following beta adrenergic blockade]. PMID- 4151497 TI - [The significance of the gamma-glutamyl-transpeptidase for the differential diagnosis of chronic aggressive and chronic persistent hepatitis (author's transl)]. PMID- 4151498 TI - Learning impairment in rats after 6-hydroxydopamine-induced depletion of brain catecholamines. PMID- 4151499 TI - Pathogenesis and treatment of decompression sickness. PMID- 4151500 TI - Problems of inert gases. PMID- 4151501 TI - [Clinical and psychological significance of the 3-4 area of the MMPI profile in women with paranoid schizophrenia]. PMID- 4151502 TI - Activities of glycolytic and citric acid cycle enzymes in oral leukoplakia. PMID- 4151503 TI - Immobilization of enzymes by radiopolymerization of acrylamide. PMID- 4151504 TI - [Retained testis]. PMID- 4151505 TI - Enzyme concentrations in serum after prolonged physical exercise. PMID- 4151506 TI - Immune response to acute otitis media in children. I. Serotypes isolated and serum and middle ear fluid antibody in pneumococcal otitis media. AB - Seventy percent of pneumococci isolated from the middle-ear cavity of infants and children with acute otitis media were of one of the seven serotypes 1, 3, 6, 14, 18, 19, or 23. The immunological response in the serum and middle-ear fluid from otitis media caused by one of these serotypes was studied in 61 children by using either indirect hemagglutination or indirect fluorescent antibody tests, or both. Twenty-six of the patients had pneumococcal antibody present in the acute serum and 28 had it in the convalescent serum by at least one method. Thirteen of the 49 middle-ear fluids examined had antibody by the indirect fluorescent antibody technique. Serum pneumococcal antibody was found to reside predominantly in the immunoglobulin G or immunoglobulin M classes, whereas pneumococcal antibody with middle-ear fluid was found to be distributed equally among all three classes. Approximately 25% of the patients (16 of 61) had a positive immune response to their infection as evidenced by increased levels of pneumococcal antibody in the convalescent serum. The percentage of patients responding immunologically increased with age: 12% of infants less than 12 months showed a significant response, whereas 48% of children over 24 months responded. PMID- 4151507 TI - Oximes of 3-formylrifamycin SV. Synthesis, antibacterial activity, and other biological properties. PMID- 4151508 TI - Nitrofurfuryl heterocycles. 12. 4-Amino-6-(5-nitro-2-furyl)isoxazolo(5,4 d)pyrimidines and 4-amino-2-(5-nitro-2-furyl)pyrimido(4,5-d)pyrimidines. PMID- 4151509 TI - Synthesis and pharmacological properties of 5a,6,7,8,9,10,10a,11 octahydrobenzo(b)cyclohepta(e)-(1,4)thiazine derivatives. PMID- 4151510 TI - [Current status concerning heart infarct, 1974]. PMID- 4151511 TI - [Basic blood pressure, relaxation blood pressure, stress blood pressure]. PMID- 4151513 TI - [Lawful checking of risk and performance]. PMID- 4151512 TI - [Relationship between overweight criteria and subjective estimation of weight]. PMID- 4151514 TI - [Causes of death in a large life insurance company for the years 1968-70]. PMID- 4151515 TI - [Progress in therapy and rehabilitation of quadriplegic patients]. PMID- 4151516 TI - Accumulation of 5-oxoproline in mouse tissues after inhibition of 5-oxoprolinase and administration of amino acids: evidence for function of the gamma-glutamyl cycle. AB - 5-Oxoprolinase catalyzes the conversion of 5-oxo-L-proline (L-pyroglutamate, L-2 pyrrolidone-5-carboxylate) to L-glutamate with concomitant stoichiometric cleavage of ATP to ADP and inorganic orthophosphate. In this reaction, a step in the gamma-glutamyl cycle, 5-oxoproline (formed by the action of gamma glutamylcyclotransferase on gamma-glutamyl amino acids, which are in turn formed by transpeptidation of amino acids with glutathione), is made available for glutathione synthesis. When mice are injected with L-2-imidazolidone-4 carboxylate, a competitive inhibitor of 5-oxoprolinase, they accumulate 5 oxoproline in their tissues (kidney, liver, brain, and eye) and excrete it in the urine. Mice given the inhibitor together with one of several L-amino acids accumulate and excrete much more 5-oxoproline than when they are given the inhibitor alone. Such augmentation of 5-oxoproline accumulation offers evidence for the function of the gamma-glutamyl cycle in vivo and supports the view that 5 oxoproline is a quantitatively significant metabolite. PMID- 4151517 TI - Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs. AB - Adenylate cyclase (EC 4.6.1.1), selectively stimulated by low concentrations of dopamine, has been found in the olfactory tubercle, the nucleus accumbens, and the caudate nucleus of several mammalian species. Several different classes of drugs effective in the treatment of schizophrenia (antipsychotic drugs) were potent inhibitors of the stimulation by dopamine of the enzyme from these various regions. The drugs studied included representatives of the phenothiazine, butyrophenone, and dibenzodiazepine classes. The inhibition by these antipsychotic drugs was competitive with respect to dopamine. The most potent of the antipsychotic agents tested was fluphenazine, which had a calculated inhibition constant (K(i)) of about 5 x 10(-9) M. For each of several drugs tested, the K(i) for the enzyme from the olfactory tubercle was similar to that for the enzyme from the caudate nucleus. Several compounds closely related structurally to the psychoactive phenothiazines, but which have little or no antipsychotic or extrapyramidal actions clinically, had low relative potencies as inhibitors of dopamine-stimulated adenylate cyclase activity. The results, considered together with other data, raise the possibility that the therapeutic effects, as well as the extrapyramidal side effects, of these antipsychotic agents may be attributable, at least in part, to their ability to block the activation by dopamine of specific dopamine-sensitive adenylate cyclases in the human brain. PMID- 4151518 TI - The stoichiometry of the conversion of cholesterol and hydroxycholesterols to pregnenolone (3beta-hydroxypregn-5-en-20-one) catalysed by adrenal cytochrome P 450. AB - The stoichiometry of the side-chain cleavage of cholesterol (cholest-5-en-3beta ol), 20alpha-hydroxycholesterol (cholest-5-ene-3beta,20alpha-diol), and 20alpha,22-dihydroxycholesterol (cholest-5-ene-3beta,20alpha,22-triol) has been examined with respect to TPNH, oxygen and H(+). Side-chain cleavage of cholesterol can be described by the following equation:Cholesterol + 3TPNH + 3H(+) + 3O(2) --> Pregnenolone (3beta-hydroxypregn-5-ene-20-one) + isocapraldehyde + 3 TPN(+) 4H(2)OStoichiometry of 20 alpha-hydroxycholesterol is 2TPNH and 2O(2) per mole of cleavage and with 20alpha, 22-dihydroxycholesterol the values are 1:1:1. In addition 1 mole of H(+) is consumed per mole of TPNH oxidized in each of these reactions. These observations are in keeping with a mechanism previously proposed in the literature, namely:Cholesterol --> 20alpha OH-Cholesterol --> 20alpha, 22-di-OH-Cholesterol --> pregnenoloneDiscordant observations are reviewed and it is concluded that insufficient data are available to sustain objections to this pathway. PMID- 4151519 TI - Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10. AB - The specific activities of both the succinate dehydrogenase-coenzyme Q(10) reductase and the DPNH-cytochrome c reductase [NADH:(acceptor)oxidoreductase, EC 1.6.99.3] were determined in mitochondria from 40 diseased gingival biopsies from patients with periodontal disease and from 24 control biopsies from nondiseased areas (clinically evaluated) of gingival tissues from the same mouths of the patients from whom the diseased gingival tissues were taken. The control tissue was taken during normal surgical procedures, such as for gingival recontouring and tuberosity removal. The diseased gingival biopsies showed a mean specific activity for the succinate dehydrogenase-coenzyme Q(10) reductase which was higher (P < 0.02) than that of the control biopsies, and which increased (P < 0.01) when the assays utilized exogenous coenzyme Q(3), and corresponded to an average deficiency of coenzyme Q(10)-enzyme activity of 35%. About 60% of the 40 diseased gingival tissues showed a deficiency of coenzyme Q(10) at its site in this succinate-coenzyme Q(10) enzyme. Of the 24 control tissues, 20% showed deficiencies of coenzyme Q(10). As a group, the control tissues showed no deficiency of coenzyme Q(10). No deficiency of coenzyme Q(10) at its site in DPNH cytochrome c reductase was observed for either the control or diseased gingival tissues, as groups or individually. PMID- 4151520 TI - Early stages in DNA binding and uptake during genetic transformation of pneumococci. AB - Ethylenediaminetetraacetate and other divalent-cation-complexing agents greatly stimulate the cellular binding of DNA molecules to competent pneumococci, while the appearance of genetic transformants and nuclease-resistant DNA binding are completely inhibited. Based on this finding, we developed an experimental system in which three early and consecutive stages of genetic transformation can be experimentally separated: (i) attachment of DNA molecules to cell surface sites that are only demonstrable in the competent state; (ii) a divalent-cation dependent nucleolytic splitting and release of the adsorbed molecules to the medium; and (iii) emergence of potential transformants accompanied by an energy requiring and divalent-cation-dependent process in which the cell-associated DNA molecules become inaccessible to shearing forces, nucleases, anti-DNA serum, and polycations. PMID- 4151521 TI - Neurotransmitters. PMID- 4151522 TI - [Pituitary-adrenal system and certain "tissue" factors of regulation in children with allergic skin manifestations]. PMID- 4151523 TI - [Endocrinological differentiation of male hypogonadism by radioimmunoassay of serum FSH, LH and testosterone levels (author's transl)]. PMID- 4151524 TI - Comparison of alpha- and beta-receptor stimulation in the circular and longitudinal muscle of the oestrogen and progesterone dominated rabbit uterus. PMID- 4151526 TI - Adrenergic regulation of glycogen breakdown in the heart and skeletal muscle. The role of alpha-adrenergic receptor. PMID- 4151525 TI - Adrenergic regulation of glycogen breakdown in the heart and skeletal muscle. The role of beta-adrenergic receptor. PMID- 4151527 TI - [Two cases of vernal conjunctivitis complicated by corneal ulcer (author's transl)]. PMID- 4151528 TI - Use of the mouse in pharmacodynamic testing. PMID- 4151529 TI - Ampicillin and tetracycline in the treatment and prophylaxis of chronic bronchitis. AB - Ampicillin and tetracycline, in doses of 2 g a day, were compared in the treatment of acute exacerbations of chronic bronchitis. Seventy-nine patients were followed for 3 to 29 months and were treated for 118 exacerbations. Clinical improvement occurred after 10 days of treatment with either drug in over 80% of the cases. Haemophilus influenzae and Diplococcus pneumoniae were eradicated from the sputum more than 60% of the time, but in general there was a poor correlation between bacteriological clearing and clinical response. The effect of chemoprophylaxis with ampicillin and tetracycline in doses of 1 g a day on the frequency of acute exacerbations of bronchitis was compared with that of a placebo. Seven hundred eighty prophylactic regimens, consisting of one capsule every 12 hr for 5 days beginning with the first sign of a cold, were prescribed for 76 patients. Irrespective of the regimen, an acute exacerbation of bronchitis was encountered at approximately 13% of the follow-up visits to the clinic. PMID- 4151530 TI - An immunochemical study of the induction of tyrosine hydroxylase in rat adrenal glands. PMID- 4151531 TI - Effect of cyanide on respiratory control of electron transporting particles. PMID- 4151532 TI - Energization of phenylalanine transport and energy-dependent transhydrogenase by ATP in cytochrome-deficient Escherichia coli K12. PMID- 4151533 TI - Binding of receptor-hydrocortisone complexes to isolated nuclei from embryonic neural retina cells. PMID- 4151534 TI - Regulation of delta-aminolevulinic acid synthetase by drugs and steroids in isolated perfused rat liver. PMID- 4151535 TI - The role of macrophages in tumour immunity. PMID- 4151536 TI - Cell replication in the follicular epithelium of the adult mosquito. PMID- 4151537 TI - Preoperative blood transfusion in the safe surgical management of pheochromocytoma: a review of 46 cases. PMID- 4151538 TI - Simple cryptorchidism: the value of the excretory urogram as a screening method. PMID- 4151539 TI - [2nd WHO Congress on various immunological problems in the study of leprosy]. PMID- 4151540 TI - Psychotropic drugs--are they justified? PMID- 4151542 TI - [The therapeutic-prophylactic effect of the tooth paste Pomorin after 4-10 years of use]. PMID- 4151541 TI - Serological types of Diplococcus pneumoniae strains isolated in Germany. Comparison with type patterns in other countries. PMID- 4151543 TI - [Dental caries in schoolchildren in Addis Ababa, Ethiopia]. PMID- 4151544 TI - Allogeneic marrow grafting using HL-A matched donor-recipient sibling pairs. PMID- 4151545 TI - [Characteristics of the oxidative phosphorylation in the brain mitochondria during hypoxia of varying duration]. PMID- 4151546 TI - [Role of Mn2+ in the equilibrium of NADP-dependent isocitrate dehydrogenases]. PMID- 4151547 TI - [Clinical action of a sedative neuroleptic (cyamepromazine)]. PMID- 4151548 TI - Energy-linked reactions in mitochondria: the effects of some inhibitors and their use in the location of the transhydrogenase enzyme. PMID- 4151549 TI - The spontaneous firing pattern of forebrain neurons. I. The effects of dopamine and non-dopamine depleting lesions on caudate unit firing patterns. PMID- 4151550 TI - 6-Hydroxydopamine and striatal acetylcholine levels. PMID- 4151551 TI - Diphasic binding of carbon monoxide with cytochrome P-450 of rat liver microsomes reduced by NADPH. PMID- 4151552 TI - Hernia and scrotal problems in childhood. PMID- 4151553 TI - Dopa decarboxylase activity in Aedes aegypti: a preadult profile and its subsequent correlation with ovarian development. PMID- 4151555 TI - At Brantford General Hospital: outreach to the disabled. PMID- 4151556 TI - Do hospitals deserve special protection? PMID- 4151554 TI - Nine deaths linked to cross-connection: Sudbury General inquest makes hospital history. PMID- 4151557 TI - A patient died; a doctor convicted: for want of a bed. PMID- 4151559 TI - Evaluation: the core of personnel management. PMID- 4151558 TI - Hospital and nursing home food service supervisors: accent on education. PMID- 4151560 TI - An overview of food-service systems. PMID- 4151561 TI - Think again about community health centres. PMID- 4151562 TI - Hospital of food service company--which is the best employer? PMID- 4151563 TI - Structural alterations in cultivated striated muscle cells from anthomedusae (hydrozoa). A metaplasiaic event. PMID- 4151564 TI - Drugs for schizophrenia. PMID- 4151565 TI - [Terminal oxidation pathways in propionic acid bacteria]. PMID- 4151567 TI - The present status of the Physician's Assistant Program of the Bowman Gray School of Medicine. PMID- 4151566 TI - [Mechanism of the formation of alpha-ketoglutaric acid by Candida lipolytica yeasts]. PMID- 4151568 TI - [Pharmacology of antihypertensive agents (author's transl)]. PMID- 4151569 TI - [Drug therapy of hypertension (author's transl)]. PMID- 4151570 TI - The pharmacologic basis for clinical use of beta adrenergic blocking drugs. PMID- 4151571 TI - [Molecular forms of glutamate dehydrogenase, NADP (H)-linked, produced by action of sodium Lusnate (author's transl)]. PMID- 4151572 TI - Cor pulmonale. PMID- 4151573 TI - Inhibition of platelet aggregation by anti-5-hydroxytryptaminic and alpha adrenergic blocking agents. PMID- 4151574 TI - Glucose 6-phosphate dehydrogenase of human blood platelets. Kinetics and regulatory properties. PMID- 4151575 TI - Chemical modification studies of chloroplast membranes. Effects of diazonium coupling on electron transfer in photosystem I. PMID- 4151576 TI - Derepression of mitochondria and their enzymes in yeast: regulatory aspects. PMID- 4151577 TI - Properties of a NADH-dependent N-hydroxy amine reductase isolated from pig liver microsomes. PMID- 4151578 TI - The enzymatic conversion of cis-(14C)phytofluene, trans-(14C)phytofluene, and trans-zeta-(14C)carotene to more unsaturated acyclic, monocyclic, and dicyclic carotenes by a cell-free preparation of red tomato fruits. PMID- 4151579 TI - Regulation by various hormones and agents of adenosine-3',5'-monophosphate levels in islets of Langerhans of rats. PMID- 4151580 TI - Effects of chronic administration of drugs which modify neurotransmitter re uptake, storage and turnover on levels of tyrosine and tryptophan hydroxylase in rat brain. PMID- 4151581 TI - Redox properties of the reduced nicotinamide adenine dinucleotide phosphate cytochrome P-450 and reduced nicotinamide adenine dinucleotide-cytochrome b5 reductases. PMID- 4151582 TI - Depression of complement activity in tree strains of mice after tumor transfer. PMID- 4151583 TI - Ultraviolet inactivation of murine leukemia virus and its assay in permissive and non-permissive cells. PMID- 4151584 TI - Arkansas Medical Society. Report of the Committee on Medical Legislation. PMID- 4151585 TI - Arkansas Medical Society. The year ahead. PMID- 4151586 TI - Arkansas Medical Society. Address of the president. PMID- 4151587 TI - Heat and cold injuries. PMID- 4151588 TI - Collaborative study of an ion exchange method for the chromatographic separation of mixtures containing expectorants, sympathomimetic amines, antihistamines, or phenothiazine in pharmaceuticals. PMID- 4151589 TI - Herpesvirus saimiri: viability in four species of hematophagous insects and attempted insect transmission to marmosets. PMID- 4151590 TI - Fatty acid desaturation by mammary gland microsomes from lactating mice. PMID- 4151591 TI - Problems faced by hypertensive patients. PMID- 4151592 TI - [Driving ability as influenced by various drugs]. PMID- 4151593 TI - Army physicians' attitudes about physicians' assistants. PMID- 4151595 TI - Effects of metamphetamine, pipradrol and methylphenidate on instrumental conditioning and spontaneous motor activity in the immature rat. PMID- 4151594 TI - [Progress in the field of drug development. 6]. PMID- 4151596 TI - Three forms of the tentacled and non-tentacled fresh-water coelenterate polyp genera Craspedacusta and Calpasoma. PMID- 4151597 TI - [Intraosseous administration of olemorphocycline in the primary surgical treatment of open fractures of the hand and foot]. PMID- 4151598 TI - [Eye burns caused by jellyfish venom]. PMID- 4151599 TI - Inborn errors of metabolism-the relationship of clinical and biochemical abnormalities. PMID- 4151600 TI - Untoward effects of a sympathomimetic amine. PMID- 4151601 TI - Alternate pathways of L-rhamnose transport in Arthrobacter pyridinolis. PMID- 4151602 TI - Two-step binding of adenosine diphosphate to L-glutamate dehydrogenase. Effect on the binding of reduced nicotinamide adenine diphosphate and on enzymatic catalysis. PMID- 4151603 TI - Pharmacological properties of a new beta-blocking agent (1-isopropylamino-3-(2 methyl-3-nitrophenoxy)-propan-2-ol). PMID- 4151604 TI - Differentiation of neuroblastoma cells induced in culture by 6-thioguanine. PMID- 4151605 TI - Joint action of diquat and related one-electron transfer agents with propoxur and fenthion against mosquito larvae. PMID- 4151607 TI - An automated lighting cycler for the insectary. PMID- 4151606 TI - Biological evaluations of slow release formulations of aldicarb. PMID- 4151608 TI - The elimination of graft-versus-host cells from an immune population. A potential tool in cancer immunotherapy. PMID- 4151609 TI - Treatment of severe asthma. PMID- 4151610 TI - By the London post. Continuing education and the state of medical practice. PMID- 4151611 TI - Neurotransmitter synthesis in inner ear and lateral line sense organs. PMID- 4151612 TI - Factors influencing the microsomal metabolism of 3H-reserpine. PMID- 4151614 TI - [Effect of pharmacological vagotomy on choleretic function of liver (author's transl)]. PMID- 4151613 TI - [Effect of metiamide, an antagonist of histamine H2-receptors, on gastric secretion (author's transl)]. PMID- 4151615 TI - Effect of phenformin on gluconeogenesis in perfused rat liver. II. Dependence on the ATP-ADP ratio. PMID- 4151616 TI - Ultrastructural evidence for a sensory-motor neuron in Ctenophora. PMID- 4151617 TI - [Principles of combining hypotensive agents (review of the literature)]. PMID- 4151618 TI - [The future of eosinophilic pleurisies]. PMID- 4151619 TI - The effect of treatment provided by dentists and therapists in the South Australian School Dental Service. PMID- 4151620 TI - Intermolecular energy transfer in the bioluminescent system of Aequorea. PMID- 4151621 TI - Early events in lens regeneration: changes in cyclic AMP concentrations during initiation of RNA and DNA synthesis. PMID- 4151622 TI - Haemodynamic and coronary vascular responses after beta-adrenoceptor blockade in the anaesthetised dog: a comparison of tolamolol with practolol and propranolol. PMID- 4151623 TI - Seasonal changes in phenylethanolamine-N-methyl transferase and monoamine oxidase activity in the ground squirrel (Citellus citellus). PMID- 4151625 TI - On the presence of subarachnoid fluid in the mudpuppy, Necturus maculosus. PMID- 4151624 TI - Haemolymph gases and buffers in Ascaris lumbricoides. PMID- 4151626 TI - Red squirrel metabolism during incline running. PMID- 4151627 TI - Comparative investigations on lipolysis and re-esterification in adipose tissue of man and various species of mice. PMID- 4151628 TI - Effects of black widow spider venom on acetylcholine release from Torpedo electric tissue slices and subcellular fractions in vitro. PMID- 4151629 TI - Effect of dietary dilution on food intake, weight gain, plasma glucose and insulin and adipose tissue insulin sensitivity in rats. PMID- 4151630 TI - Seasonal changes in calcium, magnesium, copper and zinc content in the liver of the common frog, Rana temporaria L. PMID- 4151631 TI - Digestive enzymes in Eurytoma amygdali and their relation to food digestion and to the boring process of the emergence holes in almond fruits. PMID- 4151632 TI - Urate and cation interactions in the liquid and precipitated fractions of avian urine, and speculations on their physico-chemical state. PMID- 4151633 TI - Temperature regulation in the tree shrew Tupaia glis. PMID- 4151634 TI - Effects of cystine, niacin and taurine on cholesterol concentration in the Japanese quail with comments on bile acid metabolism. PMID- 4151635 TI - Coronary-supplied compact shell of ventricular myocardium in salmonids: growth and enzyme pattern. PMID- 4151636 TI - Relations between heart muscle enzyme pattern and directly measured tolerance to acute anoxia. PMID- 4151637 TI - Evaporative heat loss in the California sea lion and harbor seal. PMID- 4151638 TI - The enzymatic content of the venoms of the sea nettle and the Portuguese man-o' war. PMID- 4151639 TI - Nematocyst lipids of the Portuguese man-of-war Physalia physalis. PMID- 4151641 TI - [Ganglioblocking and muscarinolytic activity of a series of phosphinic acid derivatives]. PMID- 4151640 TI - On the biosynthesis and composition of sterols and sterolesters in some sea anemones (Anthozoa). PMID- 4151642 TI - Influence of methamphetamine and neuroleptic drugs on tyrosine hydroxylase activity. PMID- 4151643 TI - Haemodynamic and coronary vascular responses after beta-adrenoceptor blockade in the anaesthetised dog: a comparison of tolamolol with practolol and propranolol. PMID- 4151645 TI - Impact of fluoridated water on the caries-experience of Naval recruits. PMID- 4151644 TI - Fibrinogen and metastases. PMID- 4151646 TI - [Experiment on the inclusion of vegetables in closed biological life-support systems]. PMID- 4151647 TI - [Chemical composition of green plants during long-term cultivation on an ion exchange substrate]. PMID- 4151648 TI - [Hemolysis, formation of Heinz bodies and of methemoglobin under therapy with Azulfidine (author's transl)]. PMID- 4151649 TI - Neuroanatomy of the mesothoracic ganglion of the cockroach Periplaneta americana (L.). I. The roots of the peripheral nerves. PMID- 4151650 TI - [Contraindicated medications in ocular hypertension]. PMID- 4151651 TI - [The detection of bromoureide-poisoning in skeletal finds (author's transl)]. PMID- 4151652 TI - [Stability of drugs in lyophilic suppository bases. IV. Identification of decomposition products of cyclovegantine isolated from suppositories]. PMID- 4151653 TI - Studies on electron transport and energy-linked reactions using mutants of Escherichia coli. PMID- 4151654 TI - The electromechanochemical model for energy coupling in mitochondria. PMID- 4151655 TI - Choreo-athetosis and encephalopathy induced by phenytoin. AB - Two patients with intractable epilepsy who had been treated with various combinations of anticonvulsant drugs developed phenytoin encephalopathy. In both patients choreo-athetoid involuntary movements were prominent. Blood phenytoin concentrations were above 30 mug/ml. When phenytoin was given in smaller doses and its level in the blood fell the involuntary movements and other clinical manifestations disappeared. PMID- 4151656 TI - Enterococcal lung abscess: medical and surgical therapy. PMID- 4151657 TI - Data set provides uniformity, flexibility. PMID- 4151658 TI - [Goodpasture's syndrome]. PMID- 4151659 TI - [Present status of treatment of immunodeficiency with special reference to cellular immunologic deficiency]. PMID- 4151660 TI - [Retentio testis or cryptorchism]. PMID- 4151661 TI - [Comparative study of the polyol dehydrogenases of Candida tropicalis X9, growing on D-xylose, and of its mutant capable of growing on L-arabinose]. PMID- 4151664 TI - Report of the International Executive Committee on the Thirteenth International Congress of Radiology from the International Commission of Radiation Units and Measurements (ICRU). PMID- 4151663 TI - Psychological factors associated with rheumatoid arthritis: review of the literature. PMID- 4151662 TI - Effect of inhibitors of mitochondrial protein synthesis on the NADH and NADPH glutamate dehydrogenases in yeast. PMID- 4151665 TI - [Survey of the DMP and CEO indices in 2,128 students of the Partido de Moreno, Province of Buenos Aires, Argentine Republic]. PMID- 4151666 TI - [Dynamics of airways microbial pattern in patients with infective-allergic bronchial asthma (author's transl)]. PMID- 4151667 TI - [Problem of sprained feet]. PMID- 4151668 TI - [Phenamine antagonism as a treat for experimental evaluation of neuroleptics]. PMID- 4151669 TI - [The effect of psychostimulators on the concentration of Ca and Mg ions in different regions of the rat brain]. PMID- 4151670 TI - [Correlation between the curare-like activity and adverse properties of a series of a series of diphenylcyclobutane dicarboxylic acid derivatives]. PMID- 4151671 TI - Sterol metabolism. XXIX. On the mechanism of microsomal lipid peroxidation in rat liver. PMID- 4151672 TI - Explaining variability in caries experience using an ecological model. PMID- 4151673 TI - The effect of N-alkyl chain length of stereochemistry on the absorption, metabolism and during excretion of N-alkylamphetamines in man. PMID- 4151674 TI - Metaproterenol. PMID- 4151675 TI - Drugs for relief of nausea and vomiting. PMID- 4151676 TI - A new fungus which attacks mosquitoes and related Diptera. PMID- 4151677 TI - [Chronic refractory coronary insufficiency (its causes and therapy)]. PMID- 4151678 TI - [Experimental unilateral cryptorchism in rats]. PMID- 4151679 TI - Letter: Physical examinations by physician's assistants. PMID- 4151680 TI - Plasma testosterone and estradiol concentration in prepubertal boys with cryptorchidism before and after dexamethasone and after human chorionic gonadotropin administration. PMID- 4151681 TI - Iproveratril: a nonspecific antagonist of peripheral vascular reactivity. PMID- 4151682 TI - [The effectiveness of a fluorophosphate toothpaste on children's teeth]. PMID- 4151683 TI - Studies on mitochondrial proteins. II. Localization of components in the inner membrane: labeling with diazobenzenesulfonate, a non-penetrating probe. PMID- 4151684 TI - [Nitrogenous extractive substances of invertebrate muscle tissue]. PMID- 4151685 TI - Proceedings: Influence of beta blocking agents on cardiac function and myocardial oxygen consumption in the isolated supported heart preparation of the dog. PMID- 4151686 TI - Proceedings: Beta-adrenergic blocking and antiarrhythmic activities of 1-(7 indenyloxy)-3-tert-butylaminopropane-2-OL hydrochloride (YB-11). PMID- 4151687 TI - Proceedings: Effect of acetaldehyde on hepatic microsomal drug-metabolizing enzyme activities in vitro. PMID- 4151688 TI - Proceedings: Physiological and pharmacological studies on 'caudate spindle'. PMID- 4151689 TI - Proceedings: Pharmacological actions of palythoatoxin isolated from the zoanthid, Palythoa tuberculosa. PMID- 4151690 TI - Proceedings: A pharmacological analysis of a putative neurotransmitter substance released from the non-adrenergic inhibitory nerve. PMID- 4151691 TI - Proceedings: Presynaptic actions of beta-blockers. PMID- 4151692 TI - [Glucagon in heart failure]. PMID- 4151694 TI - Pharmacokinetic properties of the beta-adrenergic receptor blocking drugs. PMID- 4151693 TI - Pharmacodynamic properties of beta-adrenergic receptor blocking drugs in man. PMID- 4151697 TI - Adverse effects of beta-adrenergic receptor blocking drugs on respiratory function. PMID- 4151695 TI - Beta-adrenergic receptor blocking drugs in angina pectoris. PMID- 4151696 TI - Adverse reactions to beta-adrenergic receptor blocking drugs: a report from the Boston collaborative drug surveillance program. PMID- 4151699 TI - [Introduction: 1. Scientific meeting and seminar on cerebrovascular diseases]. PMID- 4151698 TI - Hepatic metabolism in normal and genetically obese mice. PMID- 4151700 TI - Clinical use of piperacetazine in dogs and cats. PMID- 4151701 TI - Responses of the murine myeloid colony-forming cell to ansamycin antibiotics. AB - The in vitro susceptibility of murine myeloid colony-forming cells to the antiproliferative activities of three ansamycin antibiotics was determined. These cells were found to be 10- to 40-fold more susceptible than the corresponding human ones. PMID- 4151702 TI - Fluorescence and phosphorescence of antihistamines having the diphenylmethane chromophore. Effect of halide ions on luminescence. PMID- 4151703 TI - [Specialized, plastic, and reconstructive surgery. Cooperative care of mid-facial injuries]. PMID- 4151704 TI - Effects of centrophenoxine on the lipofuscin pigments in the nervous system of old rats. PMID- 4151705 TI - Influence of light and darkness on the turnover of noradrenaline in the rat heart. PMID- 4151706 TI - The prevalence of injured anterior teeth in English schoolchildren and adults. PMID- 4151707 TI - [Effect of adrenergic blockade on experimental hyperlipemia in rats]. PMID- 4151708 TI - Pulmonary infiltrates with eosinophilia. PMID- 4151709 TI - A comparison of thymus dependent and thymus independent antibody responses made by different numbers and populations of immunocompetent cells. PMID- 4151711 TI - Proceedings: Acute and subacute toxicities of levomethiomeprazine. PMID- 4151710 TI - Acute psychosis. PMID- 4151712 TI - I.M.A. and the international medical fraternity. PMID- 4151713 TI - Proceedings: Circulatory responses to insulin administration in the rabbit. 2. Effects of adrenergic blockade. PMID- 4151715 TI - Comparison of three- and four-year medical school graduates. PMID- 4151714 TI - The coronary blood flow effects caused by the carotid sinus reflex and the exogenous catecholamine. PMID- 4151716 TI - Patient management by telephone by child health associates and pediatric house officers. PMID- 4151717 TI - Peripheral facial paralysis and systemic disease. PMID- 4151718 TI - [Experimental study of Dolispan in the therapy of peptic ulcer]. PMID- 4151719 TI - Inflammation and "writing syndrome" inducing effects of PGE1 PGE2 and the inhibition of these actions. PMID- 4151720 TI - A liveborn triploid infant. PMID- 4151721 TI - Ribonucleoside 5'-thiodiphosphates as substrates for Escherichia coli ribonucleotide reductase. PMID- 4151722 TI - NADPH-dependent formation of thymidine diphosphodihydrostreptose from thymidine diphospho-D-glucose in a cell-free system from Streptomyces griseus and its correlation with streptomycin biosynthesis. PMID- 4151723 TI - Control of lipid metabolism in adipose-tissue homogenates of fasted refed rats. PMID- 4151724 TI - Aplysia acetylcholine receptors: blockade by and binding of alpha-bungarotoxin. PMID- 4151725 TI - Reaction of ozone with nicotinamide and its derivatives. PMID- 4151726 TI - [Mental effects of kavain]. PMID- 4151727 TI - [Rabies antibody determination with the neutralization test (N-test) and the indirect fluorescence antibody test (IFA-test) in comparison (author's transl)]. PMID- 4151728 TI - Salmonella in pigs on farms feeding pellets and on farms feeding meal. PMID- 4151729 TI - [Distribution of anaerogeny and immobility in E. coli (author's transl)]. PMID- 4151730 TI - Kanamycin and neomycin resistance in Mycobacterium ranae (fortuitum) associated with serological and biochemical markers. PMID- 4151731 TI - [Assimilation of creatinine, creatine and guanidoacetic acid by Ceratocystis stenoceras strain IP 1013-70 (F. Mariat) (author's transl)]. PMID- 4151732 TI - [Cardiac component of the systemic depressor reflex]. PMID- 4151733 TI - The release of acetylcholine from the brain: an approach to the study of the central cholinergic mechanisms. PMID- 4151735 TI - Stabilizing the alkali-generated fluorescent derivatives of NAD and NADP. PMID- 4151734 TI - Regulation of fatty-acid synthesis in higher animals. PMID- 4151736 TI - Modification of the "decarboxylase" method of glucose specific radioactivity determination. PMID- 4151737 TI - On the peptidoglycan of the cell walls of Pseudomonas aeruginosa. Structure of the peptide side chains. PMID- 4151738 TI - [Therapeutic measures in angina pectoris vera]. PMID- 4151739 TI - Letter: Caries and cereals. PMID- 4151740 TI - Letter: Caries and cereals. PMID- 4151741 TI - Implication of a tryptophyl residue in the active site of dihydrofolate reductase. PMID- 4151742 TI - Equilibrium kinetic study of the catalytic mechanism of oxidative deamination of alanine by bovine liver glutamate dehydrogenase. PMID- 4151743 TI - Intestinal secretion. PMID- 4151744 TI - [Drug interactions between preparations used in anesthesia (premedication and anesthesia) in healthy subjects]. PMID- 4151745 TI - [Interactions between drugs used in anesthesia-resuscitation in the pre-, per- and postoperative stages and various types of drugs]. PMID- 4151746 TI - The conversion of cortisol to 11beta-hydroxyandrostenedione by beef adrenal tissue. PMID- 4151747 TI - Amino acid metabolism. PMID- 4151748 TI - [Sleep deprivation (review of the literature)]. PMID- 4151749 TI - Acute hemodilution: its effect of hemodynamics and oxygen transport in anesthetized man. AB - The effects of acute normovolemic hemodilution on hemodynamics, oxygen transport, tissue perfusion and blood volume were studied. The subjects were four patients undergoing total hip replacement with prebleeding and hemodilution under fluoroxene and nitrous oxide anesthesia. The hematocrit was reduced to 29% and 21% by bleeding in two steps with simultaneous infusion of plasmanate and lactated Ringer's solution. The major compensation was a rise in CO to 123% and 136%. Systemic oxygen transport (COX arterial O(2) content) was only slightly reduced and the arteriovenous oxygen difference decreased. Tissue perfusion remained excellent. Blood volume was slightly expanded. The procedure was well tolerated by this group of selected patients, and homologous blood utilization was markedly reduced. PMID- 4151750 TI - Why do schizophrenic patients refuse to take their drugs? PMID- 4151751 TI - Course of transplanted cadaver donor kidneys with previously existing pathology. AB - Seventeen cases were studied in which the contralateral donor kidney was available for comparison with the transplanted kidney after it was removed from the host following varying periods of survival. The following morphologic observations were made: Arteries exhibiting arteriosclerosis appeared, in the new host, to take on a distinct new cellular deposit which was superimposed on the previously existing hyalinization in the intima. Except for one instance in which the host had secondary hyperparathyroidism, calcification in the donor organ did not undergo significant change. In some instances, the lymphocytes which existed in the donor kidney prior to transplantation appeared to undergo proliferation and produce a localized graft-versus-host reaction in the recipient. PMID- 4151753 TI - [Performing of injections, infusions, and blood-specimen collections by allied health personnel]. PMID- 4151752 TI - Neuromuscular effects of the nematocyst toxin from the scyphozoan medusa, Chrysaora quinquecirrha. PMID- 4151754 TI - Failure of beta-adrenergic receptor blockade to prevent arrhythmias induced by sympathetic nerve stimulation. AB - Cardiac arrhythmias produced by electrical stimulation of the ventrolateral cardiac sympathetic nerve in dogs were not blocked by the combined administration of propranolol and practolol in amounts that completely blocked cardiac beta adrenergic receptors. Blockade of cardiac alpha-adrenergic receptors, as well as cardiac cholinergic receptors, also had no influence on the arrhythmias. These results suggest that the adrenergic neuroeffector junction is fundamentally different from any hitherto described, differing perhaps in the neurotransmitter involved or in the nature of the receptor. PMID- 4151755 TI - [Onchocerciasis in Mexico]. PMID- 4151757 TI - [Pulmonary tuberculosis chemotherapy topics at the XXII International Conference on Tuberculosis in Tokyo]. PMID- 4151756 TI - Glucose 6-phosphate and 6-phosphogluconate dehydrogenases and their control mechanisms in Escherichia coli K-12. PMID- 4151758 TI - Tentative correlations between some spectroscopic and biological properties of phenothiazine and parafluorobutyrophenone derivatives. PMID- 4151759 TI - The use of mass spectrometry for the identification of metabolites of phenothiazines. PMID- 4151761 TI - Tissue accumulation of metabolites during chronic administration of piperazine substituted phenothiazine drugs. PMID- 4151760 TI - Binding of phenothiazines and related compounds to tissues and cell constituents. PMID- 4151762 TI - The binding behavior of phenothiazines and structurally related compounds to albumin from several species. PMID- 4151763 TI - Sex differences in long-term adverse effects of phenothiazines. PMID- 4151764 TI - Evolutionary origin of extrapyramidal disorders in drug-treated mental patients, its significance, and the role of neuromelanin. PMID- 4151765 TI - Pigmented hyperkeratosis among schizophrenic patients treated with nicotinic acid. PMID- 4151766 TI - The use of combined gas chromatography-mass spectrometry techniques for the identification of hydroxylated and dihydroxylated metabolites of phenothiazine drugs. PMID- 4151767 TI - The pharmacokinetics of butaperazine in serum. PMID- 4151768 TI - Chemical, pharmacological, and metabolic considerations on thiothixene. Introduction: chemical and pharmacological relationship of thioxanthenes and phenothiazines. PMID- 4151769 TI - Prevention of delirium tremens: use of phenothiazines versus drugs cross dependent with alcohol. PMID- 4151770 TI - Clinical effectiveness of piperacetazine injection in schizophrenic patients: a controlled study. PMID- 4151771 TI - Effect of phenothiazines on central cholinergic activity. PMID- 4151772 TI - The action of chlorpromazine on the metabolism of cyclic adenosine 3',5' monophosphate. PMID- 4151773 TI - Prevention of rejection reaction without general immunosuppression. PMID- 4151774 TI - A comparison of clindamycin and penicillin V in the treatment of oral infections. PMID- 4151775 TI - Prevalence and treatment of vitamin D deficiency in children on anticonvulsant drugs. PMID- 4151776 TI - Studies of adrenergic mechanisms in relation to histamine sensitivity in children immunized with Bordetella pertussis vaccine. PMID- 4151777 TI - Letter: Testicular tumors in unilateral cryptorchidism. PMID- 4151778 TI - Effect of cis-platinum(II)diamminedichloride and gallium nitrate on the ability of spleen cells to induce a graft-versus-host reaction. PMID- 4151779 TI - Natural focality of viral infections transmitted by mosquitoes. PMID- 4151780 TI - Virological investigation of mosquitoes in different seasons of the year at the natural focus of the Tahyna virus in southern Moravia. PMID- 4151781 TI - Potentiation of the antihypertensive action of hydralazine by timolol in spontaneously hypertensive rats. PMID- 4151782 TI - To the seasonal occurrence of the virus Tahyna. PMID- 4151783 TI - The microsporidian Plistophora culicis Weiser, 1946 in different mosquito hosts. PMID- 4151784 TI - Experimental pneumococcal meningitis I: a rabbit model. PMID- 4151785 TI - The vector efficiency of Culiseta annulata mosquito in relation to Tahyna virus. PMID- 4151786 TI - Isolation and characterization of prosthecae of Asticcacaulis biprosthecum. PMID- 4151787 TI - Uncommon connective tissue disorders in childhood. PMID- 4151788 TI - The effects of phenothiazines on endocrine function: I. Patients with inappropriate lactation and amenorrhoea. PMID- 4151789 TI - The effects of phenothiazines on endocrine function: II. Effects in men and post menopausal women. PMID- 4151790 TI - Effects of cytosine arabinoside on differential gene expression in embryonic neural retina. I. Accumulation of glutamine synthetase with suppression of macromolecular synthesis. AB - The analogue of cytidine, cytosine arabinoside (Ara-C), elicited a significant increase in the level of glutamine synthetase (GS) in embryonic chick neural retina in the absence of the steroid inducer of the enzyme. The increase was due to de novo synthesis of GS and was mediated by RNA which accumulated in the presence of the effective concentration of Ara-C. Accumulation of GS did not result from the inhibition of DNA synthesis for which Ara-C is best known. This new effect of Ara-C involves differential suppression of macromolecular synthesis in this system: the concentration of Ara-C which caused maximum GS accumulation suppressed overall protein and RNA syntheses 65-75% without inhibiting the transcription and translation of templates essential for GS synthesis. Withdrawal of Ara-C resulted in restoration of RNA synthesis and cessation of GS accumulation, even though preformed templates for the enzyme were present; however, if all RNA synthesis was arrested with actinomycin D at the time of Ara C withdrawal, GS continued to accumulate. The results are consistent with the hypothesis that Ara-C differentially affects the activity of structural and regulatory genes involved in the regulation of GS levels in the retina: Ara-C allows transcription of the enzyme-specific templates, but reversibly inhibits the expression of regulatory genes which limit the accumulation of GS. PMID- 4151791 TI - Benzamidopiperidines. 3. Carbocyclic derivatives related to indoramin. PMID- 4151792 TI - [The masticatory system and psychological stress]. PMID- 4151793 TI - [Dental caries occurrence in various industries in Iasi]. PMID- 4151794 TI - [Pharmacological and basic biochemical data concerning nootrope therapy]. PMID- 4151795 TI - Pheochromocytoma. PMID- 4151796 TI - [Identification of group B Streptococci (Streptococcus agalactiae) by means of the "triple-test" of Wallerstrom and the CAMP-test (author's transl)]. PMID- 4151797 TI - [KCNS (RK and RM)-,Bacitracin- and CAMP-tests for the identification of some groups of Streptococci (author's transl)]. PMID- 4151798 TI - Studies on biochemical variants of Sh. flexneri. I. Studies on the lactose positive variants of Sh. flexneri 2a. PMID- 4151799 TI - Studies on biochemical variants of Sh. flexneri. II. Studies on mannitol negative variants of Sh. flexneri 3a. PMID- 4151800 TI - [A quantitative study of Bacteroides corrodens and similar bacteria in human tonsils (author's transl)]. PMID- 4151801 TI - [Demonstration of lysine decarboxylase activity in the obligately anaerobic Bacterium Sphaerophorus varius (author's transl)]. PMID- 4151802 TI - Antimicrobial spectrum of Triclosan, a broad-spectrum antimicrobial agent for topical application. PMID- 4151803 TI - Investigations on the mode of action of Triclosan, a broad spectrum antimicrobial agent. PMID- 4151804 TI - An improved apparatus for separation of mosquito eggs from soil. PMID- 4151805 TI - Studies on the medical ecological epidemiology in mangrove areas in Thailand. PMID- 4151806 TI - Amino acid transmitters in the mammalian central nervous system. PMID- 4151808 TI - [On the pathological evolution and personality structure of children and adolescents suffering from endogenous-phasic psychoses and reactive depressions (author's transl)]. PMID- 4151807 TI - Review of clinical trials with pipotiazine, pipotiazine undecylenate and pipotiazine palmitate. PMID- 4151809 TI - Neuroleptic agents in anesthesia. PMID- 4151810 TI - Nonparalytic poliovirus infections in patients with severe combined immunodeficiency disease. PMID- 4151811 TI - Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection. AB - 18 Carcinogens, including aflatoxin B(1), benzo(a)pyrene, acetylaminofluorene, benzidine, and dimethylamino-trans-stilbene, are shown to be activated by liver homogenates to form potent frameshift mutagens. We believe that these carcinogens have in common a ring system sufficiently planar for a stacking interaction with DNA base pairs and a part of the molecule capable of being metabolized to a reactive group: these structural features are discussed in terms of the theory of frameshift mutagenesis. We propose that these carcinogens, and many others that are mutagens, cause cancer by somatic mutation. A simple, inexpensive, and extremely sensitive test for detection of carcinogens as mutagens is described. It consists of the use of a rat or human liver homogenate for carcinogen activation (thus supplying mammalian metabolism) and a set of Salmonella histidine mutants for mutagen detection. The homogenate, bacteria, and a TPNH generating system are all incubated together on a petri plate. With the most active compounds, as little as a few nanograms can be detected. PMID- 4151812 TI - Octopamine: presence in single neurons of Aplysia suggests neurotransmitter function. AB - Octopamine has been identified and measured in individual neurons from Aplysia californica. Neither dopamine nor norepinephrine was detected in these cells. Thus, in Aplysia there may be separate populations of catecholaminergic and monophenolaminergic cells. Octopamine may have functions of its own in the central nervous system of mollusks. PMID- 4151813 TI - Effects of hypothermia on halothane MAC and isoflurane MAC in the rat. PMID- 4151814 TI - Involvement of molybdenum and iron in the in vitro assembly of assimilatory nitrate reductase utilizing Neurospora mutant nit-1. PMID- 4151815 TI - Age bias in referral for psychological consultation. PMID- 4151816 TI - [Current review of clinical enzymology. Gamma-glutamyltranspeptidase (gamma-GT): valuable aid for diagnosis in hepatology]. PMID- 4151817 TI - [Familial association of Zinsser-Engman-Cole syndrome and chronic lymphatic leukemia]. PMID- 4151818 TI - Transplantation of allogeneic lymphoid cells specifically depleted of graft versus host reactive cells. PMID- 4151819 TI - Reversal of the perfusion defect in experimental canine lobar pneumococcal pneumonia. PMID- 4151820 TI - IVMA '74 table topics. PMID- 4151821 TI - Evidence for the presence of glutamate synthase in extracts of carrot cell cultures. PMID- 4151822 TI - Functional characteristics of the interneurons of wind-sensitive hair-receptors on the head in Locusta migratoria L. I. Interneurons with excitatory responses. PMID- 4151823 TI - Functional characteristics of the interneurons of wind-sensitive hair receptors on the head in Locusta migratoria L. II. Interneurons with inhibitory responses. PMID- 4151824 TI - Studies on the blood sugar level in the grass snake (Natrix natrix L.). PMID- 4151825 TI - Effect of insulin on the blood sugar level in the grass snake (Natrix natrix L.). PMID- 4151826 TI - Heart rate and physiological thermoregulation in a basking turtle, Pseudemys scripta elegans. PMID- 4151827 TI - Observations on extrarenal excretion by orbital glands and osmoregulation in Malaclemys terrapin. PMID- 4151828 TI - Effects of inorganic anions and cations on oxygen binding of haemoglobin from Arenicola marina (Polychaeta). PMID- 4151829 TI - Effect of vasotocin and glucagon on plasma growth hormone levels in the pigeon. PMID- 4151830 TI - Temperature regulation responses of ornate box turtles, Terrapene ornata, to heat. PMID- 4151831 TI - Catecholamine content and histology of the adrenal glands of the nutria (Myocastor coypus). PMID- 4151832 TI - The effects of heating and cooling in water on the heart rate of the bullfrog. PMID- 4151833 TI - Blood glucose in crayfish. II. Variations induced by artificial stress. PMID- 4151834 TI - Effects of environmental temperature on food intake in growing pigs. PMID- 4151835 TI - Studies on the red blood cell oxygen affinity and 2,3-diphosphoglyceric acid in the hibernating woodchuck (Marmota monax). PMID- 4151836 TI - On a peculiarity of planarian digestion. PMID- 4151837 TI - [Fluoridation at Karl Marx Stadt. IX. Caries statistical results after 12 years of control]. PMID- 4151838 TI - Adaptation of hepatic phenylalanine hydroxylase in the rat. PMID- 4151839 TI - Letter: Adverse reactions to beta-adrenergic blockade. PMID- 4151840 TI - [Development of parasitology and the Academy of Sciences of the USSR]. PMID- 4151842 TI - Adenylate cyclase activity in lymphoid organs during regional and systemic graft versus-host reactions. PMID- 4151841 TI - Octopamine: selective association with specific neurons in the lobster nervous system. PMID- 4151843 TI - [Letter: Responsibility of medical assistants in hemodialysis]. PMID- 4151844 TI - The HL-A system. I. Genetics and molecular biology. PMID- 4151845 TI - Immunogenetic disparity and graft-versus-host reactions. PMID- 4151846 TI - The double barrier in bone marrow transplantation. PMID- 4151847 TI - Immunosuppression for clinical marrow transplantation. PMID- 4151848 TI - Bone marrow transplantation in the treatment of acute leukemia. PMID- 4151849 TI - Psychiatric drugs and trends: review of the phenothiazines. 1. PMID- 4151850 TI - [Effect of bacterial tyrosine decarboxylase and tyramine on tyrosine and alanine aminotransferase activity of the liver in white mice]. PMID- 4151851 TI - The role of nonoxidative metabolism in organophosphorus resistance. PMID- 4151852 TI - Overcrowding factors of mosquito larvae. V. Synthesis and evaluation of some branched-chain fatty acids against mosquito larvae. PMID- 4151853 TI - [Classification of the mental changes during the late period following myocardial infarct in relation to the tasks of rehabilitation]. PMID- 4151854 TI - [Macrocellular neurosecretory nuclei of the thalamus in hypertensive syndrome in late pregnancy toxemia patients]. PMID- 4151855 TI - [Immunologic phenomena in lymphogranulomatosis]. PMID- 4151856 TI - Histological, histochemical and electron microscopic studies on effects of diphtheria toxin on the adrenals of guinea pigs. PMID- 4151857 TI - Comparative studies in vivo and in vitro of rat-liver enzymes. PMID- 4151858 TI - Cellular basis of cardiac dysrhythmias. PMID- 4151859 TI - Cardiac effects of beta-adrenergic receptor antagonists. PMID- 4151860 TI - The central action of histamine. 3. The effect of antazoline and thenalidine on the brain noradrenaline and 5-hydroxytryptamine levels and behavior of rats receiving histamine intraventricularly. PMID- 4151861 TI - The effect of drugs interfering with biogenic amine metabolism on basal gastric secretion in the rat. PMID- 4151862 TI - Alteration of tyrosine aminotransferase activity in hepatoma cells in tissue culture by amphotericin B. AB - Two clonal lines of rat hepatoma cells, in tissue culture, that have steroid inducible tyrosine aminotransferase (TAT) activities were shown to have different responses to amphotericin B. One of the cell lines (HTC) was relatively resistant to the growth-inhibiting effects of amphotericin B and demonstrated an inhibition of only its steroid-inducible TAT activity when exposed to the antifungal agent. In contrast, not only was the other cell line (MHC) sensitive to amphotericin B during its growth, but uninduced and induced enzyme activities were affected. During the first few hours after the exposure of MHC cells to amphotericin B, both basal and dexamethasone-induced TAT activity were reduced; with continued exposure, enzyme activity increased over that of untreated cells and was superinduced in the presence of maximal, stimulating amounts of steroid. The mechanisms by which enzyme activity is induced by amphotericin B are probably different from those mediated by steroids. PMID- 4151863 TI - Proceedings: A morphological and pharmacological study of the parietal cells of the stomach in the dog during periods of maximal acid output and after the gastric secretory inhibitor UK-9040. PMID- 4151864 TI - Proceedings: Effect of H2-receptor blockade on vagally induced gastric secretion and gastric emptying in man. PMID- 4151865 TI - Proceedings: Inhibition of nocturnal acid secretion in duodenal ulcer by oral metiamide. PMID- 4151866 TI - Proceedings: Initial observations on the inhibitory action of urogastrone on gastric secretory responses in man. PMID- 4151868 TI - Proceedings: Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease. PMID- 4151867 TI - Proceedings: Effects on prostaglandin biosynthesis of drugs affecting gastrointestinal function. PMID- 4151869 TI - Strabismus. Foreword. PMID- 4151870 TI - [Endocrine polyadenomatosis with acute hyperparathyroidism]. PMID- 4151871 TI - [Astrocytes and dehydrogenase activities in non-tumoral epilepsies (author's transl)]. PMID- 4151873 TI - Solubilization of testosterone 5 alpha-reductase from nuclear fraction of rat ventral prostate. PMID- 4151872 TI - The effect of silver ions on the respiratory chain of Escherichia coli. PMID- 4151874 TI - Non-prescription drugs during pregnancy: potential teratogenic and toxic effects upon embryo and fetus. PMID- 4151875 TI - [Periarteritis nodosa with Australia antigenemia in the course of antituberculous treatment]. PMID- 4151876 TI - [Ganglionic blockaders in the treatment of gastrointestinal hemorrhage]. PMID- 4151877 TI - Presidential adress: Perspectives in pediatrics in India for the seventies. PMID- 4151878 TI - [Disturbance of metabolism in the development of neurogenic lesions of the heart and the effect on them of certain pharmacological agents]. PMID- 4151879 TI - [Role of the thyroid gland in humoral regulation of hematopoiesis]. PMID- 4151880 TI - [Influence of the hydrosoluble vitamin content of the diet and treatment by barbiturates on several effects of azoic dyes]. PMID- 4151881 TI - New concepts in primate production. Report on the Battelle Seattle Research Center Conference, August 11-12, 1972. PMID- 4151882 TI - Charge transfer interactions of chlorpromazine with neural transmitters. PMID- 4151883 TI - Stereochemical studies on medicinal agents. 10. The role of chirality in alpha adrenergic receptor blockage by (plus)-and(minus)-phenoxybenzamine hydrochloride. PMID- 4151884 TI - The Roberts syndrome. PMID- 4151885 TI - Nitrate reductase from Spinacea oleracea. Reversible inactivation by NAD(P)H and by thiols. PMID- 4151886 TI - [Results in the prevention of dental caries by fluoridation of table salt]. PMID- 4151887 TI - On the conformation of NADP-dependent isocitrate dehydrogenase from Bacillus stearothermophilus. PMID- 4151888 TI - Reaction of chloroplasts with diazonium-1, 2, 4-triazole. PMID- 4151890 TI - Report of the commission on the armed forces dental services, 1972-1973. PMID- 4151889 TI - Emergency treatment for injuries to anterior teeth. PMID- 4151891 TI - Annual report of the commission on dental practice 1972-1973. PMID- 4151892 TI - Report of the regional organisation of the F.D.I. for Europe. October 1972-July 1973. PMID- 4151893 TI - 3-Methylcholanthrene-inducible binding of aromatic hydrocarbons to DNA in purified rat liver nuclei. PMID- 4151894 TI - Letter: Phenothiazines in delirium tremens: pro and contra. PMID- 4151895 TI - The effects of droperidol on modifying the hypertensive response to ketamine. PMID- 4151896 TI - Present day management of hypertension. PMID- 4151897 TI - Oxygen effects on mortality of mice infected with Diplococcus pneumoniae. PMID- 4151899 TI - [Seventh International Congress for Suicide Prevention]. PMID- 4151900 TI - [A clinical comparison of two drug combinations in allergic rhinitis]. PMID- 4151901 TI - Evaluation of self-administered prophylaxis and supervised toothbrushing with acidulated phosphate fluoride. PMID- 4151898 TI - Muscarinic cholinergic binding in rat brain. AB - Binding sites with high affinity and specificity for [(3)H]quinuclidinyl benzilate (QNB) are present in homogenates of rat brain. The characteristics of the binding sites resemble those of muscarinic cholinergic receptors. Specific binding is saturable with respect to [(3)H]QNB and tissue concentration and is time-, temperature-, and pH-dependent. The bimolecular rate of association (2.0 x 10(8) M(-1) min(-1)) and dissociation (1.2 x 10(-2) min(-1)) at 35 degrees indicate a dissociation constant of 60 pM and a density of 65 pmol/g of brain. Muscarinic antagonists and agonists displace specific [(3)H]QNB binding, while nicotinic and non-cholinergic drugs possess little affinity for [(3)H]QNB-binding sites. PMID- 4151902 TI - Serum complement-fixing antibodies in human dental caries. PMID- 4151903 TI - G6PD San Jose: a new variant characterized by NADPH inhibition studies. PMID- 4151904 TI - T-cell-mediated immune responses induced in vitro: a probe for allograft and tumor immunity. PMID- 4151906 TI - [Occurrence of dental caries and fillings in 16 year-olds at Gothenburg. Results of a radiographic study from 3 schools]. PMID- 4151905 TI - [Histochemical studies of the reaction of the endometrium to estro-progestagens administered at various stages of the cycle]. PMID- 4151907 TI - Twenty years of community water fluoridation: the prevalence of dental caries among Providence, R.I. school children. PMID- 4151908 TI - [Orthostatic hypotensive disorders in a neuropsychiatric department. Their correction by Praxinor]. PMID- 4151909 TI - Antagonism of cardiac arrhythmias by dl-1-(2-acetyl-4-butyramidophenoxy)-2 hydroxy-3-isopropylaminopropane (M & B 17,803A), a new beta adrenoreceptor blocking agent. PMID- 4151910 TI - Cardiovascular effects of dl-1-(2-acetyl-4-butyramido-phenoxy)-2-hydroxy-3 isopropylaminopropane (M & B 17,803A), a new cardioselective beta adrenoreceptor blocking agent. PMID- 4151911 TI - Studies on enhancement of cardiac and renal allografts in the rat. PMID- 4151912 TI - Transplantation tolerance and enhancement. Concepts and questions. PMID- 4151913 TI - Histological study of increased vascular permeability in thermal injury in the sheep. PMID- 4151914 TI - [Arthropathies in so-called collagen diseases]. PMID- 4151916 TI - [Studies on body image. 2]. PMID- 4151915 TI - Effect of acidulated phosphate-fluoride chewable tablets on dental caries in schoolchildren: results after 30 months. PMID- 4151917 TI - Gamma-glutamyl-transpeptidase in hepato-biliary disease--value as an enzymatic liver function test. PMID- 4151918 TI - Gas exchange in a cerianthid. PMID- 4151919 TI - The membrane actions of tranquilizers in relation to neuroleptic-induced parkinsonism and tardive dyskinesia. PMID- 4151920 TI - Pharmacokinetics of 14C-dimethothiazine. I. Distribution and excretion following oral administration in the dog and rat. PMID- 4151921 TI - Clinical differences among phenothiazines in schizophrenics. Introduction: specific indications for antipsychotics: elusive end of the rainbow. PMID- 4151922 TI - Effect of surfactants in the presence and absence of testosterone on the activity of two liver enzymes of tumor-bearing rats. PMID- 4151923 TI - Comparison of tyrosine hydroxylase and dopamine-beta-hydroxylase inhibition with the effects of various 6-hydroxydopamine treatments on d-amphetamine induced motor activity. PMID- 4151924 TI - [Three cases of intersexuality in the dog (author's transl)]. PMID- 4151926 TI - Proceedings: Studies on cyclic nucleotides in the adrenal gland. V. Adenyl and guanyl cyclase activities in the cortex and medulla of the adrenal gland. PMID- 4151925 TI - Light-dependent synthesis of glutamate in Rhodospirillum rubrum. Physiological evidence for ammonia assimilation via the glutamine synthetase and glutamine: 2 oxoglutarate amino-transferase system. PMID- 4151927 TI - Proceedings: Effects of convalsants and ions in the external solution on invertebrate neuron. PMID- 4151928 TI - Proceedings: Antihypertensive action of beta-blockers. PMID- 4151929 TI - Proceedings: Interaction between possible transmitters and butyrophenones applied microelectrophoretically in the cerebellum and basal ganglia of the cat. 1. Interaction in the purkinje cells of the cat cerebellum. PMID- 4151930 TI - Proceedings: The effect of alpha-adrenergic blocking agents on hypogastric ganglion from guinea-pig. PMID- 4151931 TI - [Hormonal dependency of gamma-glutamyl transpeptidase (author's transl)]. PMID- 4151932 TI - Role of beta-receptor vascular tone in the vasodilating action of some drugs. PMID- 4151934 TI - [The use of beta adrenergic receptor stimulants in the prevention of premature labor and abortion]. PMID- 4151933 TI - Characteristics of the nuclear and microsomal steroid delta-4-5 alpha-hydrogenase of the rat prostate. PMID- 4151935 TI - [Criteria for standardizing the evaluation of damage from occupational diseases; scope and results of the two joint congresses of the INAIL Patronati held in Torino]. PMID- 4151936 TI - The feeding response to beta-adrenergic active agents during induced compensatory growth in rats. PMID- 4151937 TI - Glutathione reductase test with whole blood, a convenient procedure for the assessment of the riboflavin status in humans. PMID- 4151938 TI - [Central and other pharmacological actions of syrosingopine (O carbethoxysyringoyl methylreserpate)]. PMID- 4151939 TI - [Rubinstein Taybi syndrome. Report of two cases (author's transl)]. PMID- 4151940 TI - Chemistry and biochemistry of the neomycins. XVI. Synthesis and bioactivity of hexa-N-benzylneomycins. PMID- 4151941 TI - The effect of endotoxin of Escherichia coli on the graft-versus-host reaction in mice. II. Non-H-2 systems. PMID- 4151942 TI - The effect of Escherichia coli endotoxin on the graft-versus-host reaction in mice. 3. Runt disease in newborns. PMID- 4151943 TI - Gamma-glutamyl transpeptidase: a clinical and experimental study. PMID- 4151944 TI - Dissociation of catecholamine-induced formation of adenosine 3'5'-monophosphate and release of glycerol in fat cells by prostaglandin E1, E2 and N6 phenylisopropyladenosine. PMID- 4151945 TI - Granulomatous pulmonary arteritis. A hypereosinophilic syndrome. PMID- 4151946 TI - An evaluation of regulation of the hexose monophosphate shunt in Escherichia coli. PMID- 4151947 TI - Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. 8. Studies of the properties of E3 and its role in the formation of cytidine diphosphate-4-keto-3,6 dideoxyglucose. PMID- 4151948 TI - On the reaction of piericidin A with the reduced nicotinamide adenine dinucleotide dehydrogenase of Candida utilis. PMID- 4151949 TI - Malic enzymes of rabbit heart mitochondria. Separation and comparison of some characteristics of a nicotinamide adenine dinucleotide-preferring and a nicotinamide adenine dinucleotide phosphate-specific enzyme. PMID- 4151950 TI - Effect of tungsten and vanadium on the in vitro assembly of assimilatory nitrate reductase utilizing Neurospora mutant nit-1. PMID- 4151952 TI - [Neurohumoral aspects of myocardial infarct and its complications]. PMID- 4151953 TI - [Thiol group metabolism in the body of patients with mitral stenosis of rheumatic etiology]. PMID- 4151954 TI - [Place of saluretics in the treatment of hypertension]. PMID- 4151956 TI - Hormonal control of lysosomal enzyme release from human neutrophils: elevation of cyclic nucleotide levels by autonomic neurohormones. AB - The influence of autonomic neurohormones on the immunologic release of beta glucuronidase (EC 3.2.1.31) from, and the cyclic nucleotide levels in, human neutrophils was determined. Interaction of neutrophils with rheumatoid arthritic, serum-treated zymosan particles in a neutral balanced salt solution at 37 degrees resulted in the extracellular discharge of beta-glucuronidase without any loss of cell viability, as indicated by the failure of incubated cells to take up eosin Y or to release cytoplasmic lactate dehydrogenase (EC 1.1.1.27). Epinephrine reduced the release of beta-glucuronidase from neutrophils in the presence of zymosan during 2-30 min of incubation and elicited a concomitant elevation of adenosine 3':5'-monophosphate levels. Propranolol, a beta-adrenergic receptor antagonist, but not phentolamine, an alpha-adrenergic receptor antagonist, blocked both actions of epinephrine. Acetylcholine stimulated the release of beta glucuronidase, but not lactate dehydrogenase, and provoked a concomitant elevation of guanosine 3':5'-monophosphate levels. Atropine, a muscarinic receptor antagonist, but not hexamethonium, a ganglionic blocker, inhibited both actions of acetylcholine. Interaction of neutrophils and zymosan particles resulted in an elevation of guanosine 3':5'-monophosphate levels within 2 min. These data suggest that intracellular guanosine 3':5'-monophosphate may be involved in mediating the immunologic release of lysosomal enzymes from human neutrophils whereas adenosine 3':5'-monophosphate may inhibit enzyme release. Moreover, autonomic neurohormones appear to be capable of modulating lysosomal enzyme release by virtue of their capacity to elevate neutrophil cyclic nucleotide levels. PMID- 4151957 TI - ["What is psychotherapy?"--in three worlds]. PMID- 4151955 TI - Pleiotropy of hisT mutants blocked in pseudouridine synthesis in tRNA: leucine and isoleucine-valine operons. AB - The hisT gene codes for an enzyme responsible for the conversion of uridine to pseudouridine (Psi) in the anticodon region of many tRNA species in Salmonella typhimurium. We have previously shown that a hisT mutant has tRNA(His) which lacks pseudouridine in this region and as a consequence has an altered chromatographic behavior. We show here a similar alteration in chromatographic behavior of all tRNA(Leu) and one tRNA(Ile) species from a hisT mutant. By contrast, tRNA(Val), which contains no pseudouridine except for the one in the TPsiCG sequence, is chromatographically unaltered in a hisT mutant. The absence of pseudouridine in the anticodon region of tRNA in hisT mutants has been previously shown to cause derepression of the histidine operon. We show here that in hisT mutants the regulation of the leucine and the isoleucine and valine operons is also affected: the enzymes of these operons are refractory to repression by the branched chain amino acids. However, there is no difference between hisT and wild type in the pattern of derepression caused by isoleucine or valine limitation and only a slight difference in the enzyme levels in cells grown on minimal medium. The alteration in the regulation of branched chain amino acid operons may also explain why hisT mutants are resistant to inhibition of growth by the amino acid analogues 5,5,5-trifluoroleucine, beta-hydroxyleucine, and norleucine and by the oligopeptides glycylglycylnorleucine and norleucylnorleucine. PMID- 4151958 TI - [Symptomatic treatment of allergic rhinitis]. PMID- 4151959 TI - Fluoride uptake and caries inhibition from self-application of an acidulated phosphate-fluoride prophylaxis paste. PMID- 4151960 TI - [The development of research on circulatory pharmacology in Hungary during the past 25 years]. PMID- 4151961 TI - [Effect of neurohumoral substances on specific leukocytolysis]. PMID- 4151962 TI - Amounts of inorganic ions and free amino acids in hemolymph and ganglion of the African giant snail, Achatina fulica Ferussac. PMID- 4151963 TI - The oscillations of blood pressure in the chicken. PMID- 4151964 TI - [Differential therapeutic principles in the drug therapy of high blood pressure]. PMID- 4151965 TI - [Hypertensive emergencies]. PMID- 4151966 TI - Potential bioreductive alkylating agents. 4. Inhibition of coenzyme Q enzyme systems by lipoidal benzoquinone and naphthoquinone derivatives. PMID- 4151967 TI - Structure-activity relationships of the mitomycins and certain synthetic analogs. PMID- 4151968 TI - Benzamidopiperidines. 2. Heterocyclic compounds related to indoramin. PMID- 4151969 TI - In vitro androgen metabolism in mouse kidney: high 3-keto-reductase (3alpha hydroxysteroid dehydrogenase) activity relative to 5alpha-reductase. PMID- 4151970 TI - Multiple molecular forms of gamma-glutamyl transpeptidase during human pregnancy. PMID- 4151971 TI - Continuous pH stat assay technique for glutamine and asparagine synthetase enzyme systems, involving ATP conversion to ADP plus Pi and AMP plus PPi, respectively. PMID- 4151972 TI - Insect growth regulators: evaluation procedures and activity against mosquitoes. PMID- 4151973 TI - [Paroxysmal rhinitis. Diagnostic and therapeutic possibilities in allergic and vasomotor rhinopathies]. PMID- 4151974 TI - The nitroblue tetrazolium test. PMID- 4151975 TI - The barrier function of lymph nodes. A review of experimental studies and their implications for cancer surgery. PMID- 4151976 TI - Exacerbation of dapsone-induced Heinz body hemolytic anemia following treatment with methylene blue. PMID- 4151977 TI - Polypodium sp. (Coelenterata) found in North American sturgeon. PMID- 4151978 TI - [The photobiological role of flavins and flavoproteins in plant tissues (author's transl)]. PMID- 4151979 TI - [8th International Conference on Plant Growth Substances held in Tokyo, 8-26--9-1 1973]. PMID- 4151980 TI - [Resorption and distribution of Tempidone in the body]. PMID- 4151981 TI - Activation of 17beta-hydroxysteroid dehydrogenase from human red blood cells. PMID- 4151982 TI - Influence of changes in brain monoamine metabolism on behaviour of herpes simplex infected mice. PMID- 4151983 TI - Marrow transplants in aplastic anemia and leukemia. PMID- 4151984 TI - [The most favorable time for the treatment of cryptorchism]. PMID- 4151985 TI - A mechanism of the acceleration of lipid peroxide formation in liver homogenates and subcellular fractions of vitamin E-deficient mice. PMID- 4151986 TI - [Stimulation, stimulus conduction and myocardial excitability of the human heart under oxyfedrin therapy of bradycardic dysrhythmias (author's transl)]. PMID- 4151987 TI - [Effect of several drugs on the development of stress ulcer and seepage of a pigment from the stomach of rats]. PMID- 4151988 TI - Introduction: of syndromes and interfaces. PMID- 4151989 TI - Ocular manifestations of rheumatic disorders. Natural and iatrogenic. PMID- 4151990 TI - The skin as a reflector of immunologic change. PMID- 4151992 TI - Studies on antihistaminics in acute radiation burn. PMID- 4151991 TI - Glutamine synthetase activity in cat neocortex during the evolution of an ectosylvian spiking focus activated by pentetrazol. PMID- 4151993 TI - [The Korczak problem at international conventions in Giessen (May 23-25, 1973) and Basle (May 28-June 2, 1973)]. PMID- 4151994 TI - ["Malignant" papillomatosis of the respiratory tract]. PMID- 4151995 TI - Purification and some properties of gamma-glutamyl transpeptidase from azo dye induced hepatoma. PMID- 4151996 TI - Adaptive control of the ethanol-forming system in heterolactic acid bacteria. Effect of growth conditions on alcohol dehydrogenase synthesis in Leuconostoc mesenteroides. PMID- 4151997 TI - Mechanism of mercuric chloride resistance in microorganisms. 3. Purification and properties of a mercuric ion reducing enzyme from Escherichia coli bearing R factor. PMID- 4151998 TI - The effect of information and motivation towards dental health, and of fluoride tablets on caries in schoolchildren. I. Increment over the initial 2-year experimental period. PMID- 4151999 TI - Effective and practical preventive procedures. PMID- 4152000 TI - Asian Pacific regional organisation of FDI. Annual report 1972-73. PMID- 4152002 TI - Letter: Scleroderma and mosquitos. PMID- 4152001 TI - Effect of experimental pneumococcal meningitis on respiration and circulation in the rabbit. AB - Pathophysiological studies in bacterial meningitis in man have been limited by clinical variability and the necessity for immediate therapy. After the development of a reliable animal model of pneumococcal meningitis, we studied respiration and circulation in 25 anesthetized New Zealand white rabbits during untreated pneumococcal meningitis and in 33 healthy controls. In meningitis, we found increased lactic acid in cerebrospinal fluid (CSF). Increased ventilation, perhaps due to CSF lactic acid accumulation, resulted in respiratory alkalosis; the concomitant lowering of Pco(2) acted as a homeostatic mechanism to restore pH toward normality in the CSF. Hyperventilation increased with the duration of the illness. Cardiac output was also increased with decreased peripheral vascular resistance but with only slight reduction in mean systemic and pulmonary arterial pressures. In the final hour of life, peripheral vascular resistance fell further; ventilation declined and then abruptly ceased while cardiac activity continued. Lactic acid accumulation in the CSF, found in both experimental and human pneumococcal meningitis, may cause the hyperventilation found in this disease and may contribute to death. PMID- 4152003 TI - Transplantation in the military. I. Guidelines for cadaver organ donation. PMID- 4152004 TI - Fluoride contents of surface enamel in high- and low-fluoride areas studied with a sensitive physical method. PMID- 4152005 TI - Mechanism of lymphocyte-mediated cytolysis. The LMC cycle and its role in transplantation immunity. PMID- 4152006 TI - Histotopochemical determination of metabolic activity of carbohydrate metabolism in plaque from sound and carious enamel. PMID- 4152007 TI - [Little children and dental health. Reflections on a survey of 3-year-old children]. PMID- 4152008 TI - Significant social variables in favorable community adjustment of schizophrenics: a 5-year follow-up. PMID- 4152009 TI - Letter: Stability of gamma glutamyltransferase in serum. PMID- 4152010 TI - Letter: Interference from serum separators in drug screening by gas chromatography. PMID- 4152011 TI - [Symposium on massive hemorrhages from the digestive tube. Introduction]. PMID- 4152012 TI - [Arteritis necroticans in the course of rheumatoid arthritis]. PMID- 4152013 TI - [Behavior of some enzymes in the serum and urine in chronic renal failure]. PMID- 4152014 TI - [Gamma-glutamyl-transpeptidase in coronary cardiopathies. Special study in myocardial infarct]. PMID- 4152015 TI - [Letter: Urticaria. Color additives and antihistaminics]. PMID- 4152016 TI - The effect of phenothiazines on botulinus intoxication. PMID- 4152017 TI - Inhibition of coenzyme Q10-enzymes, succinoxidase and NADH-oxidase, by adriamycin and other quinones having antitumor activity. PMID- 4152018 TI - [Annual report 1973]. PMID- 4152019 TI - Altered glucoregulatory hormones during acute pneumococcal sepsis in the rhesus monkey. PMID- 4152020 TI - Pertussis vaccine and convulsive disorders of childhood. PMID- 4152021 TI - Medical vagotomy: new evidence of its potential usefulness as a preoperative test. PMID- 4152022 TI - Percentage contribution of increased heart rate to increased oxygen transport during activity in Pseudemys scripta, Terrapene ornata and other reptiles. PMID- 4152023 TI - Changes in hypothalamic catecholamines and serotonin during hibernation and arousal in the arctic ground squirrel. PMID- 4152024 TI - High capillary permeability in fishes. PMID- 4152025 TI - Physiological correlates of burrow gas conditions in the California ground squirrel. PMID- 4152026 TI - The effect of changes in external salinity on the non-protein nitrogenous constituents of parietal muscle from Agonus cataphractus. PMID- 4152027 TI - The resting potential of cockroach muscle membrane. PMID- 4152028 TI - Electrogenesis in cockroach muscle. PMID- 4152029 TI - [Effect of some drugs in the development and exacerbation of gastric and duodenal ulcer]. PMID- 4152030 TI - Regulation of the corticosteroid inducibility of tyrosine aminotransferase in interspecific hybrid cells. PMID- 4152031 TI - Letter: Trophic effects of striatal neuron denervation. PMID- 4152032 TI - [Letter: Peripheral blood circulation disorders due to beta receptor blockers?]. PMID- 4152033 TI - [Angiographic diagnosis of pancreatic tumour and pancreatitis (author's transl)]. PMID- 4152034 TI - Pathophsiological significance of sympathetic activity in cardiovascular diseases. PMID- 4152035 TI - Use of sympathomimetic amines in shock. PMID- 4152036 TI - Proceedings: Neural and humoral control of apocrine glands. PMID- 4152037 TI - Primary total proctocolectomy for ulcerative colitis. PMID- 4152038 TI - The urologic allied health professional. PMID- 4152039 TI - The barefoot doctors of the People's Republic of China--some problems. PMID- 4152040 TI - Systemic and coronary hemodynamic effects of intracoronary administration of prostaglandins E1 and E2. PMID- 4152042 TI - Effects of alpha and beta blockers on hemodynamics of SHR. PMID- 4152041 TI - Review: Electrolyte and antiarrhythmic drug interaction. PMID- 4152043 TI - Proceedings: Contribution of cardiovascular factors to the development of hypertension in spontaneously hypertensive rats. A preliminary report. PMID- 4152044 TI - Effect of temperature on histidine ammonia-lyase from a psychrophile, Pseudomonas putida. AB - Pseudomonas putida was able to grow at 0 C in a complex medium containing l histidine and to synthesize histidine ammonia-lyase and urocanase. The activity of the former enzyme was assessed between -10 and 60 C in cells and in cell extracts. Activity was maximal from 20 to 35 C. Below 20 C, activity decreased with temperature but, significantly, the enzyme exhibited 30% of its maximal activity at 1.5 C. The temperature response was similar in both intact cells and cell extracts, which indicated that the cell membrane did not significantly limit the entry of histidine at low temperature. Above and below the maximal temperature range, the reduced activity was not caused by irreversible inactivation, as shown by preincubation experiments. Also, when the temperature was rapidly changed from 60 to 30 C during an assay, the reaction rate increased abruptly to the full 30 C activity without a lag. This demonstrated the rapid reversibility of inactivation. The apparent Michaelis constant increased with temperature. As the substrate concentration was decreased, the enzyme activity became less dependent on temperature. The efficiency of substrate entry and catalysis near 0 C are factors in the ability of this facultative psychrophile to grow in a histidine medium at 0 C. PMID- 4152045 TI - Extracellular enzyme secretion by Pseudomonas lemoignei. AB - The ability of succinate to repress the secretion of Pseudomonas lemoignei poly beta-hydroxybutyrate depolymerase was a function of pH. Repression only occurred when the pH of the medium was 7.0 or less. At a higher pH, lack of sensitivity to succinate concentration may have been due to a limited ability to transport succinate. Actively secreting cultures (at pH 7.4) continued to secrete enzyme for approximately 30 min after the pH was rapidly decreased to pH 6.8, even though sufficient succinate was present to repress enzyme synthesis. Similarly, after the addition of rifampin to secreting cultures, there was a 30-min delay before secretion was inhibited. Evidence is presented which suggests that continued secretion may be the result of depolymerase messenger ribonucleic acid accumulation within the cells. Studies with chloramphenicol indicated that de novo protein synthesis is necessary for the secretion of poly-beta hydroxybutyrate depolymerase and that exoenzyme is not released from a preformed pool. Studies with various inhibitors of protein synthesis indicated that synthesis of exoenzyme is 5 to 10 times more susceptible to inhibition than is the synthesis of cell-associated proteins. PMID- 4152047 TI - Causes of the post-concussional syndrome. PMID- 4152048 TI - Screening of African Strychnos species for convulsant and muscle-relaxant effects. PMID- 4152046 TI - Isolation and characterization of the outer membrane of Neisseria gonorrhoeae. AB - The cell envelope of Neisseria gonorrhoeae strain 2686, colonial type 4, was isolated from spheroplasts formed by the action of ethylenediaminetetraacetic acid and lysozyme. Isopycnic centrifugation of osmotically ruptured spheroplasts resolved the cell envelope into two main membrane fractions. Chemical and enzymatic analyses were used to characterize these isolated membranes. Succinic dehydrogenase, reduced nicotinamide adenine dinucleotide oxidase, and d-lactate dehydrogenase were localized in the membrane fraction of buoyant density, rho degrees = 1.141 g/cm(3). Lipopolysaccharide and over half of the cell envelope protein were associated with the membrane that banded in sucrose at rho degrees = 1.219 g/cm(3). These fractions were consequently designated cytoplasmic and outer or L-membrane, respectively. Sodium dodecyl sulfate-polyacrylamide electrophoresis of isolated membranes demonstrated the relative simplicity of the protein spectrum of the outer membrane. The majority of the protein in this membrane could be accounted for by proteins of molecular weights 34,500, 22,000, and 11,500. The protein of molecular weight 34,500 accounted for 66% of the total protein of the L-membrane. Isoelectric precipitation at pH 4.6 with 10% acetic acid selectively removed this protein from a 150 mM NaCl in 10 mM tris(hydroxymethyl)aminomethane-hydrochloride, pH 7.4, extract of purified outer membrane. At pH 4.0, the other proteins of the L-membrane were precipitated. It was concluded that the membrane components of the cell envelope of N. gonorrhoeae were similar to those of other gram-negative bacteria. The cell envelope fractions described here, in particular the outer membrane, are sufficiently well defined to provide a valuable tool for future biochemical and immunological studies on N. gonorrhoeae. PMID- 4152049 TI - [Hypotonic duodenography. Technical modality (author's transl)]. PMID- 4152050 TI - [Peripheral receptors of autonomic nervous systems]. PMID- 4152051 TI - Dental health status of Gulf Coast Head Start. PMID- 4152052 TI - The effect of diet on formation of gamma-glutamyl transpeptidase (GGTP) inhibitor in the mouse intestine. PMID- 4152053 TI - [Sphaerule formation by a Mucor species in the internal organs of Amphibia. Prelimimary report (author's transl)]. PMID- 4152054 TI - Antischizophrenic drugs and brain cholinergic receptors. Affinity for muscarinic sites predicts extrapyramidal effects. PMID- 4152055 TI - Influence of althesin on coronary blood flow and myocardial oxygen consumption in dogs. PMID- 4152056 TI - [Effect of some adrenergic and cholinergic agents on the proteolytic activity of the gastric juice]. PMID- 4152057 TI - [Autonomic ganglion-blocking action of surugatoxin isolated from the Japanese ivory shell (Babylonia japonica)]. PMID- 4152058 TI - Enzymes of the gamma-glutamyl cycle in the ciliary body and lens. AB - The enzymes of the gamma-glutamyl cycle have been found in rabbit ciliary body and, except for 5-oxoprolinase, also in the ocular lens. Histochemical studies show that gamma-glutamyl transpeptidase is localized mainly in the basal portions of the epithelial cells of the ciliary body; the findings are similar to those observed in the chloroid plexuses. The histochemical staining reaction in the ciliary epithelium is more intense than in the chloroid plexus, intestine, and kidney. gamma-Glutamyl transpeptidase staining activity in the epithelium of the intestinal and renal proximal convoluted tubules is confined to the microvillus border. Moderate transpeptidase activity was found in the cytoplasm of nonpigmented epithelial cells of the iris at the posterior pupillary margin. The histochemical and enzyme activity studies are consistent with the thesis that the gamma-glutamyl cycle functions in transport of amino acids across the blood aqueous humor barrier. PMID- 4152059 TI - [Burimamid and metiamid, a new pharmacological principle]. PMID- 4152060 TI - D-(R)- and L-(S)-3-alkylaminopyrrolidino-substituted dihydrodibenzo (b,f)- and (b,e)thiepins, xanthenes, and diphenylmethanes. PMID- 4152061 TI - A simple, rapid method for detecting the efflux of small quantities of adenosine triphosphate from biological tissues. PMID- 4152062 TI - The salt relations of marine and halophilic species of the unicellular green alga, Dunaliella. The role of glycerol as a compatible solute. PMID- 4152063 TI - [Letter: Unusual inflammation after subtotal thyroidectomy for toxic multinodular goiter. Thyroiditis?]. PMID- 4152064 TI - [Modern achievements in the field of catecholamine biochemistry]. PMID- 4152065 TI - Orientation of membrane vesicles from Escherichia coli prepared by different procedures. PMID- 4152066 TI - On the acrylamide disc electrophoresis pattern of human G6PD. PMID- 4152067 TI - Sympathetic ganglia in organ culture. PMID- 4152068 TI - The development of catecholaminergic neurons of the central nervous system. PMID- 4152069 TI - [WHO meeting on the prevention of cholera in Europe]. PMID- 4152070 TI - [Mechanisms of regulation of biochemical processes in microorganisms]. PMID- 4152071 TI - [Mechanism of oxidative phosphorylation and general principles of bioenergetics]. PMID- 4152072 TI - The benefits of water fluoridation. PMID- 4152073 TI - [Elucidation of the significance of bacteria of the genus Pseudomonas in pathology of the preimaginal states of mosquitoes]. PMID- 4152074 TI - Distribution of the sensitivities to penicillin of types of Diplococcus pneumoniae in an American Indian population. PMID- 4152075 TI - Amoxicillin in the treatment of respiratory infections. PMID- 4152076 TI - Studies on metabolic events in localized compartments of the living cell by rapid microspectrofluorometry. PMID- 4152078 TI - [Meeting on rabies]. PMID- 4152077 TI - Effect of sweets made with and without sucrose on the dental plaque, and the correlation between the extent of plaque and human dental caries experience. PMID- 4152079 TI - Noradrenaline nerve terminals in the cerebral cortex: effects on noradrenaline uptake and storage following axonal lesion with 6-hydroxydopamine. PMID- 4152080 TI - Letter: Fenticlor, actinic reticuloid, and antihistamines. PMID- 4152081 TI - Letter: Beta-blockade in the presence of renal disease and hypertension. PMID- 4152082 TI - Bone marrow transplantation in aplastic anaemia. PMID- 4152084 TI - Dimensional changes in a fixed bridge as a consequence of four different assembly technics for soldering purposes. PMID- 4152083 TI - Attempts at altering ureteral activity in the unanesthetized, conditioned dog with commonly employed drugs. PMID- 4152086 TI - Cell-mediated reactivity and serum blocking activity in tolerant rats. Studies on ten rats operationally tolerant to skin allografts using several independent assays. PMID- 4152085 TI - [Effect of pyruvate dehydrogenase coenzymes on pyruvate oxidation and on the absorption of NAD by liver mitochondria normally and following a gravitational overload in white rats]. PMID- 4152087 TI - Coordinate control of rat liver lipogenic enzymes by insulin. PMID- 4152088 TI - [Purification and properties of Chlorella glutamine synthetase]. PMID- 4152089 TI - Catecholamine systems as the neural substrate for intracranial self-stimulation: a hypothesis. PMID- 4152090 TI - Specific protein metabolism in identifiable neurons of Aplysia californica. PMID- 4152091 TI - Amino acid levels in liver and plasma of the rat during inhibition of transamination. PMID- 4152092 TI - Histology and histochemistry of the peripheral neural plexus in the Aplysia gill. PMID- 4152093 TI - Effects of long-term organ culture on neurotransmitter metabolism in the ganglia of Aplysia californica. PMID- 4152094 TI - Prevention of injuries to anterior teeth. PMID- 4152095 TI - Proceedings: an attempt to estimate the sympathetic activity to the heart of man in his home environment. PMID- 4152096 TI - Acute arterial occlusion in the upper limbs. A follow-up study of 31 extremities. PMID- 4152097 TI - [Intention and incident in drug research, demonstrated on the example of tricyclic psychopharmacologic agents]. PMID- 4152098 TI - Prevalence of dental caries in phenylketonuric children. PMID- 4152099 TI - Prequalene pyrophosphate. A normal intermediate in squalene biosynthesis. PMID- 4152100 TI - Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. 8. Mechanistic roles of enzyme E-1 and pyridoxamine 5'-phosphate in the formation of cytidine diphosphate-4-keto-3,6-dideoxy-D-glucose from cytidine diphosphate-4-keto-6-deoxy D-glucose. PMID- 4152101 TI - Reduced nicotinamide adenine dinucleotide dehydrogenase, piericidin sensitivity, and site 1 phosphorylation in different growth phases of Candida utilis. PMID- 4152102 TI - Localization of some enzymes in the main venom glands of viperid snakes. PMID- 4152103 TI - [Aerobic metabolism of propionic acid bacteria]. PMID- 4152104 TI - [Relationship between stem cells, blood and immuno-competent lymphatic system (review)]. PMID- 4152105 TI - [About the chemical differentiation of the in vitro cultivated ganglion trigeminale (author's transl)]. PMID- 4152106 TI - Cyclic AMP and adrenergic receptors in Gambusia affinis melanophore response in vitro. PMID- 4152107 TI - [The in vitro formation of 5 alpha-dihydrotestosterone by the testis of Discoglossus pictus]. PMID- 4152108 TI - Comparative study of two beta-adrenergic blocking drugs in angina pectoris. PMID- 4152109 TI - Effects of temperatures and activity on aerobic and anaerobic metabolism and heart rate in the turtles Pseudemys scripta and Terrapene ornata. PMID- 4152110 TI - Hemolymph DNA concentrations during the molting cycle of the fresh water crayfish, Procambarus clarkii. PMID- 4152111 TI - Increase of Na-K-ATPase activity in renal cortex of hamster (Mesocricetus auratus) during pre-hibernation cold exposure. PMID- 4152112 TI - Melanophore aggregation in the plaice (Pleuronectes platessa L.) I. Changes in vivo sensitivity to sympathomimetic amines. PMID- 4152113 TI - Melanophore aggregation in the plaice (Pleuronectes platessa L) II. In vitro effects of adrenergic drugs. PMID- 4152114 TI - Facilitated diffusion in erythrocytes of mammals. PMID- 4152115 TI - Neonatal 6-hydroxydopamine sympathectomy in normotensive and spontaneously hypertensive rat. PMID- 4152116 TI - Sar1-Ala8 angiotensin II blocks renin-angiotensin but not beta-adrenergic dipsogenesis. PMID- 4152117 TI - Salbutamol and quinterenol: dipsogenic action produced by beta-adrenergic stimulants. PMID- 4152118 TI - Neurochemical bases of defensive behavior in animals. AB - This paper presents a literature review and the author's own investigations devoted to identifying the morphological organization of different subcortical structures and neurochemical processes involved in the (regulation of defensive behavior. The effects of intrahypothalamic injections of two cholinomimetic substances, carbachol and d-tubocurarine, on rage and fear reactions were explored. Also the investigations were carried out with intrahypothalamic injections of anticholinergic substances, atropine and betamon or hexamethonium, which block selectively muscarinic and nicotinic receptors. The results indicate that carbachol injected into the hypothalamus after blocking the muscarinic receptors with atropine fails to elicit any defensive response; whereas carbachol injection administrated after nicotinic receptors had been blocked by betamon or hexamethonium induces full aggressive behavior. This indicated that carbachol acts, on the hypothalamic level, through the muscarinic receptors. The mechanism of d-tubocurarine action seems to be more complex because this compound induces fear response after either the muscarinic or the nicotinic receptors have been blocked. A possible mechanism based on chemically differentiated neuronal circuits at the hypothalamic level for two different defensive drives, fear and rage, is presented. PMID- 4152119 TI - A new antihistaminic drug (Tavegyl) in allergic diseases. PMID- 4152120 TI - Major tranquillizers in the management of psychasthenic neurosis. PMID- 4152121 TI - [Spontaneous regression of Ehrlich ascites tumour by infection with pneumococci (author's transl)]. PMID- 4152122 TI - Effects of oxygen and glucose on energy metabolism and dimorphism of Mucor genevensis grown in continuous culture: reversibility of yeast-mycelium conversion. AB - Mucor genevensis was grown in both glucose-limited and glucose-excess continuous cultures over a range of dissolved oxygen concentrations (<0.1 to 25 muM) to determine the effects of glucose and the influence of metabolic mode (fermentative versus oxidative) on dimorphic transformations in this organism. The extent of differentiation between yeast and mycelial phases has been correlated with physiological and biochemical parameters of the cultures. Under glucose limitation, oxidative metabolism increased as the dissolved oxygen concentration increased, and this paralleled the increase in the proportion of the mycelial phase in the cultures. Filamentous growth and oxidative metabolism were both inhibited by glucose even though mitochondrial development was only slightly repressed. However, the presence of chloramphenicol in glucose-limited aerobic cultures inhibited mitochondrial respiratory development but did not induce yeast-like growth, indicating that oxidative metabolism is not essential for mycelial development. Once mycelial cultures had been established under aerobic, glucose-limited conditions, subsequent reversal to anaerobic conditions or treatment with chloramphenicol caused only a limited reversal (<35%) to the yeast-like form. Glucose, however, induced a complete reversion to yeast-like form. It is concluded that glucose is the most important single culture factor determining the morphological status of M. genevensis; mitochondrial development and the functional oxidative capacities of the cell appear to be less important factors in the differentiation process. PMID- 4152123 TI - Proceedings: Some morphologic and pharmacologic observations on the apocrine glands in the tail of the goat. PMID- 4152124 TI - Studies on D-tetrose metabolism. IV. Purification and some properties of D erythrulose reductase from beef liver. PMID- 4152125 TI - [Study of diols as a synthetic energy source in the diet of young rats]. PMID- 4152126 TI - [Enzymes in bone diseases and cholestasis]. PMID- 4152127 TI - Cholesterol and cholesterol sulfate as substrates for the adrenal side-chain cleavage enzyme. PMID- 4152129 TI - Evidence of the direct aromatization of testosterone and different aromatization sites for testosterone and androstenedione in human placental microsomes. PMID- 4152128 TI - Catalysis of pentose phosphate pathway reactions by cytoplasmic fractions from muscle, uterus and liver of the rat, and the presence of a reduced nicotinamide adenine dinucleotide phosphate-triose phosphate oxidoreductase in rat muscle. AB - 1. The enzymes of the pentose phosphate pathway were assayed in supernatant fractions from rat muscle, liver and uterus. 2. On incubation of ribose 5 phosphate with uterus and liver supernatants, triose phosphate, sedoheptulose 7 phosphate and hexose monophosphate accumulated. 3. When a muscle supernatant was used, glycerol 3-phosphate instead of triose phosphate appeared and there was a negligible accumulation of hexose monophosphate. 4. Hexose monophosphate production from ribose 5-phosphate was also followed by measuring NADP(+) reduction in the presence of an excess of phosphoglucose isomerase, glucose 6 phosphate dehydrogenase and 6-phosphogluconate dehydrogenase. 5. With a muscle supernatant, NADPH was reoxidized as rapidly as it was formed owing to the presence of a NADPH-triose phosphate oxidoreductase. 6. A modification of the pentose phosphate pathway in skeletal muscle incorporating this enzyme is proposed. PMID- 4152130 TI - Actions of metiamide, an H2-histamine receptor antagonist, on gastric H+ and pepsin secretion in dogs. PMID- 4152131 TI - Role of mosquitoes in transmission of hepatitis B virus infection. PMID- 4152132 TI - Comparison of ampicillin and amoxicillin in the treatment of otitis media in children. PMID- 4152133 TI - Middle ear infections in pediatric patients: treatment with amoxicillin. PMID- 4152134 TI - Treatment of otitis media in pediatric practice: amoxicillin versus ampicillin. PMID- 4152135 TI - Infections of the lower respiratory tract: treatment with amoxicillin. PMID- 4152136 TI - Amoxicillin in infections in patients with cancer. PMID- 4152137 TI - Selectivity of interferon action: hormonal induction of tyrosine aminotransferase in rat hepatoma cells is much less sensitive to interferon than the replication of vesicular stomatitis virus or reovirus. PMID- 4152138 TI - Adenylate cyclase in a sea anemone. Implication for chemoreception. PMID- 4152139 TI - The relative significance of CO2-fixing enzymes in the metabolism of rat brain. PMID- 4152140 TI - Letter: Beta-blockade in the presence of renal disease and hypertension. PMID- 4152141 TI - A 4-year follow-up of vulnerable adolescents. The prediction of outcomes in early adulthood from measures of social competence, coping style, and overall level of psychopathology. PMID- 4152143 TI - Interspecific variability of soluble isocitrate dehydrogenase in primates. PMID- 4152142 TI - Effects of a synthetic estrogen upon steroid bioconversion in vitro in testes of patients with prostatic cancer. PMID- 4152144 TI - [Effect of para-chloromercuribenzoate on glutamate dehydrogenases in Chlorella]. PMID- 4152145 TI - Futher studies on the nature of phenylalanine hydroxylation in brain. PMID- 4152146 TI - Cyclic nucleotide metabolism in human photoreceptors. PMID- 4152147 TI - Interactions of Ca, P, Zn and alkaline phosphatase in the chick. 3. Effects of dietary phosphate, NaCl and theophylline. PMID- 4152148 TI - Regulation of plasma Na+ and K+ concentrations in five African species of Tilapia fishes. PMID- 4152149 TI - Oxygen equilibria of the vascular and coelomic hemoglobins of the terebellid polychaete, Pista pacifica. Evidence for an oxygen transfer system. PMID- 4152151 TI - [Use of gamma glutamyl transpeptidase, 5'-nucleotidase, and alkaline phosphatase isoenzymes in the differential diagnosis of liver diseases]. PMID- 4152152 TI - [Prevention and treatment of motion sickness]. PMID- 4152150 TI - Beta-adrenergic receptor blocking drugs in hypertrophic cardiomyopathy, autonomically mediated cardiovascular functional disorders and Fallot's tetralogy. PMID- 4152153 TI - The detection of Klinefelter's syndrome at birth. PMID- 4152154 TI - m-Hydroxybenzoate 4-hydroxylase from Aspergillus niger: purification and properties. PMID- 4152155 TI - Synthesis of fatty acids from malonyl-CoA and NADPH by pigeon liver fatty acid synthetase. PMID- 4152156 TI - NADP+-specific isocitrate dehydrogenase of Escherichia coli. II. Subunit structure. PMID- 4152157 TI - Some new paramagnetic centers in submitochondrial particles detectable by EPR spectroscopy. PMID- 4152158 TI - Adaptive response of hepatic acetyl-CoA carboxylase to dietary alterations in genetically obese mice and their lean controls. PMID- 4152159 TI - Summary and recommendations of the workshop on cancer detection in the health care delivery system. PMID- 4152161 TI - Male infertility. Current diagnosis and treatment. PMID- 4152162 TI - Chlorpropamide overdosage: delayed and prolonged hypoglycemia. PMID- 4152163 TI - Proceedings: Hazards of maternally administered drugs. PMID- 4152164 TI - Editorial: The pharmacology and therapeutic use of beta-adrenergic receptor blocking drugs in cardiovascular disease. PMID- 4152165 TI - [Histones of some invertebrates]. PMID- 4152166 TI - [Survey of periodontal and DMF indexes in a sample of 1,306 students Lujan, Province of Buenos Aires, Argentine Republic]. PMID- 4152168 TI - Glutamic acid: selective depletion by viral induced granule cell loss in hamster cerebellum. PMID- 4152169 TI - [Differentiation between real and apparent beta receptor blockade in the heart]. PMID- 4152170 TI - [Standard stomatologic surveillance of drinking water fluoridation]. PMID- 4152167 TI - Beta-adrenergic receptor blocking drugs in hypertension. PMID- 4152171 TI - Pathway of infection of mosquito iridescent virus. I. Preliminary observations on the fate of ingested virus. AB - Mosquito iridescent virus (MIV) is ingested in large amounts by first- and second instar Aedes taeniorhynchus larvae without causing a high rate of infection. Electron microscope studies have been undertaken to determine the fate of ingested virus. Preliminary observations suggest that most, if not all, ingested particles are degraded shortly after entering the midgut. MIV and other virus particles employed in this study were apparently unable to penetrate the peritrophic membrane; consequently, none was observed inside, or in contact with, midgut epithelial cells. PMID- 4152172 TI - [Healing of cancellous bone grafts (author's transl)]. PMID- 4152173 TI - Potentiation of the antiinflammatory action of prednison by several synthetic antihistaminics. PMID- 4152174 TI - Chromatography of cell suspensions: a simple method for the determination of pyridine nucleotides. PMID- 4152175 TI - Studies of the metabolism of carbon disulfide by rat liver microsomes. PMID- 4152176 TI - Metabolic adaptations in fatty acid and lactose biosynthesis by sheep mammary tissue during cessation of lactation. PMID- 4152177 TI - The relationships between measures of general depression and the endogenous versus reactive classification. PMID- 4152178 TI - Letter: Piperacetazine-induced failure to ejaculate. PMID- 4152179 TI - Glutamine synthetase of Bacillus stearothermophilus. I. Purification and basic properties. PMID- 4152180 TI - Mechanism of the luminescent intramolecular reaction of aequorin. PMID- 4152181 TI - Nuclear magnetic resonance study of the complexes of manganese(II) and fully adenylated glutamine synthetase (Escherichia coli W). Frequency, temperature, and substrate dependence of water proton relaxation rates. PMID- 4152182 TI - Evidence for circulation of Sindbis virus and other arboviruses by using sentinel animals in Western Slovakia. PMID- 4152183 TI - Immunologic modification: a basic survival mechanism. PMID- 4152184 TI - Some properties of erythrocyte glucose-phosphate dehydrogenase in psoriatics. PMID- 4152185 TI - The lonely legend of Norman Bethune. PMID- 4152186 TI - [Pathomorphology of the myocardium in chronic chromium poisoning (experimental histochemical study)]. PMID- 4152187 TI - Uterine pressures during fluroxene anesthesia. PMID- 4152188 TI - Dobutamine, a new beta agonist. PMID- 4152189 TI - Acute respiratory insufficiency and cor pulmonale. Pathophysiology, clinical features, and management. II. Management. PMID- 4152190 TI - The pharmacology of severe bronchial asthma. PMID- 4152191 TI - Liver structure and function in cholelithiasis: effect of chenodeoxycholic acid. AB - Although, in suitable patients, oral chenodeoxycholic acid (CDCA) dissolves gallstones, the results of recent animal studies suggest that it might be hepatotoxic. Liver function was therefore studied in patients with gallstones before and during treatment with CDCA and liver biopsies were carried out both in patients with cholelithiasis given bile acid therapy and in those who had been given no medical treatment. In 25 patients treated with 0.5-1.5 g CDCA/day (7-20 mg kg body weight(-1) day(-1)) there was no significant change in serum bilirubin, albumin, globulin, transaminase, isocitric dehydrogenase, alkaline phosphatase, and gamma glutamyl transpeptidase levels before and at monthly intervals during six months' treatment. The kinetics of bromsulphthalein (BSP) clearance and its apparent transport maximum were not significantly changed during CDCA therapy. The mean fasting serum bile acid concentrations of 18.0 +/- SEM 1.2 mumoles/litre before and 20.0 +/- 3.5 mumoles/litre during treatment were both significantly greater than control values. Liver histology was not appreciably different in 11 patients treated with CDCA from that in eight patients with untreated cholelithiasis and in three patients who had received CDCA three to four months before biopsy. These results suggest that in doses of 0.5 to 1.5 g/day CDCA is not hepatotoxic in man. PMID- 4152192 TI - Relationships of psychological dimensions to impairment in a population with cerebrovascular insufficiency. PMID- 4152193 TI - [Study of an enzyme complex in rheumatism in children and adults]. PMID- 4152194 TI - [Effect of phytohemagglutinin and antilymphocyte serum on the survival time of homologous skin grafts in mice]. PMID- 4152195 TI - Endocrine variations in the course of the immunologic process, from its onset to its extinction, and the relationship to the nervous system type. PMID- 4152196 TI - The influence of radiation on blood vessels and circulation. Chapter X. Blood flow and permeability in irradiated skin. PMID- 4152197 TI - Blockade of insulin release by certain phenothiazines. PMID- 4152198 TI - Modified system in vitro for the metabolism of 2-acetylaminofluorene. PMID- 4152199 TI - Methylprednisolone acetate and its use in the treatment of students with hay fever at examination time. PMID- 4152200 TI - [Australia antigen and rheumatoid patients]. PMID- 4152201 TI - T cell response to viral and bacterial infection. PMID- 4152202 TI - Immunity to infection, allograft immunity and tumour immunity: parallels and contrasts. PMID- 4152203 TI - Topographical definition of new sites on the mitochondrial electron transport chain. PMID- 4152204 TI - American Nurses' Association: Convention '74. PMID- 4152205 TI - Role of a deoxyribonuclease in the genetic transformation of Diplococcus pneumoniae. AB - Two steps in the uptake of DNA by Diplococcus pneumoniae were characterized by analyzing mutants defective in transformation. A strain deficient in the two major deoxyribonucleases of D. pneumoniae takes up DNA normally and converts it to single strands within the cell and oligonucleotide fragments outside the cell. Extracts of this strain contain a residual deoxyribonuclease that produces similar oligonucleotide fragments in vitro. This enzyme is missing in transformation-defective mutants blocked in the second or entry step. Cells of this mutant class bind large amounts of DNA to their surface in a form accessible to external agents. Another class of nontransformable mutants fails to bind DNA at all. Their deoxyribonuclease content is unchanged, and they are apparently blocked in the first or binding step of DNA uptake. The binding step requires a source of energy and prior activation of the cells by competence factor. Entry may be independent of these requirements and may come about by action of the deoxyribonuclease on one strand of DNA with energy for the transport of the intact strand deriving from hydrolysis of the degraded strand. The enzyme may thus act as a DNA translocase. PMID- 4152206 TI - Protection of lethally irradiated mice by spleen cells from neonatally thymectomized mice. AB - Long-lived, immunologically vigorous (C3H(f) x A(f))F(1) hybrids were produced after lethal irradiation by administration of spleen cells from C3H(f) or syngeneic donors. Further, neonatally thymectomized C3H(f) or A(f) strain donors reconstituted irradiated C3H(f) or (C3H(f) x A(f))F(1) hosts. In addition, C3H(f) spleen cells from nonthymectomized 10- to 15-day-old donors protected irradiated hybrid mice, but A(f) cells of young mice as well as of older mice produced graft versus-host reaction and early death in irradiated C3H(f) or (C3H(f) x A(f))F(1) hybrids. Abrogation of secondary disease by treatment of irradiated mice with spleen cells from allogeneic neonatally thymectomized mice is possibly attributable to diminished immunologic competence of the cells grafted, followed by the development of immunological tolerance of the donor cells. Donor cells, receiving thymus influence in the recipient host after transplantation, could explain the long-lived immunologically vigorous radiation chimeras that did not experience graft-versus-host reactions. The findings of this study help to understand the differential susceptibility of A(f) and C3H(f) mice to development of tolerance to one another's antigens observed in prior investigations. It appears that, in these mice, the host thymus influences the maturation of the spleen cells from young mice or from neonatally thymectomized mice. However, this influence was often greater in mice given 767 rads than in those given 1046 rads. This differential influence is possibly attributable to irradiation damage to the thymus produced by the higher dose of irradiation. Spleen cells from neonatally thymectomized mice can be differentiated and expanded by the thymus of the host. The differential susceptibility of T(1), early differentiation stages, of thymus dependent lymphocytes and T(2), late differentiation stages, of thymus-dependent lymphocytes to tolerance induction and immunostimulation, respectively, are proposed as the bases for these otherwise paradoxical influences. PMID- 4152207 TI - Enzymatic aziridine synthesis from beta amino-alcohols--a new example of endogenous carcinogen formation. PMID- 4152208 TI - H2-receptors in peripheral blood vessels. PMID- 4152209 TI - [Pharmacology of hypotensive substances]. PMID- 4152210 TI - Rat liver D-amino acid oxidase activity in iron deficiency anemia. PMID- 4152211 TI - Pitfalls in the study of steady state kinetics of enzymes: spurious inhibition patterns due to stray light errors. PMID- 4152212 TI - Studies on enzyme reactions related to steroid biosynthesis. 3. Distribution of the testicular enzymes related to androgen production between the seminiferous tubules and interstitial tissue. PMID- 4152213 TI - [Neurologic manifestations of collagen diseases]. PMID- 4152214 TI - [Awaiting the X session of the Codex Alimentarius Commission FAO-WHO]. PMID- 4152215 TI - Kinetics of glucose-6-phosphate dehydrogenase from normal and neoplastic mammary tissue. PMID- 4152216 TI - Lymphocyte plasma membranes. I. Thymic and splenic membranes from inbred rats. PMID- 4152217 TI - [Fulminating ulcero-hemorrhagic rectocolitis with toxic megacolon. Treatment by emergency colectomy]. PMID- 4152218 TI - Effects of 2,2'(methylenediimino)bis-1,3,4-thiadiazole (NSC-143019) on tumor growth and immune responses in mice. PMID- 4152219 TI - On the pharmacology and biochemistry of the amine-uptake mechanism in human blood platelets. AB - 1. The uptake of 5-hydroxytryptamine (5-HT) by human blood platelets in vitro has been studied with the object of identifying the biochemical mechanisms involved.2. Drugs active in adrenergic systems are only moderate inhibitors of uptake, although prenylamine is as active as the less potent tricyclic anti depressive drugs; phenoxybenzamine is almost inactive as a competitive inhibitor but is effective if pre-incubated with the platelets beforehand. This parallels its pharmacological pattern of action.3. Inhibitors of oxidative phosphorylation do not inhibit 5-HT uptake, but iodoacetate inhibits, if pre-incubated with the platelets; p-chloromercuribenzoate does also, when the platelets are suspended in synthetic medium, but not in plasma.4. Ouabain causes significant inhibition at 10(-7)M; by 10(-6)M it achieves its maximal effect, namely 40% inhibition; in K(+)-deficient medium, uptake falls to 30% of normal; the K(+)-dependent fraction of the uptake includes the ouabain-sensitive component. Mg(++) has no effect.5. A drug not possessing the imipramine structure, which has been tried in the treatment of depressive illness, 4-phenyl bicyclo (2,2,2) octan-1-amine, is a highly potent inhibitor of 5-HT uptake. PMID- 4152220 TI - The inhibition of histamine uptake and metabolism by burimamide in the guinea-pig atrium and in mouse neoplastic mast cells, in vitro. AB - Burimamide, an H(2)-receptor blocking agent, has been shown capable of blocking the uptake and metabolism of [(14)C]-histamine, both in the guinea-pig isolated atrium and in murine neoplastic mast cells. This occurs even at concentrations far below the dose range capable of blocking the positive chronotropic effect of histamine in the isolated atrium. In the atrium, very low concentrations of burimamide were found capable of blocking histamine metabolism. PMID- 4152221 TI - Histoenzymatical approach to the chemoarchitectonics of the basal nuclei in the developing rat brain. PMID- 4152222 TI - Bacteriocidal properties of a class of quinoid compounds related to sporulation in the mushroom, Agaricus bisporus. AB - A small phenolic compound, gamma-L-glutamyl-4-hydroxybenzene, and several quinoid derivatives appear in the gill tissues of the mushroom, Agaricus bisporus, during the prodromal period of sporulation. These quinoids markedly inhibit respiratory enzymes and protein synthesis. The temporal relationship of their appearance to sporulaton and their properties as metabolic inhibitors indicate that they initiate and maintain the dormant or cryptobiotic state of the spore. In very low concentrations, these quinoids show significant bacteriocidal action against a variety of microorganisms. The therapeutic potential of these antibiotic properties is considered. PMID- 4152223 TI - Lysosomal physiology in Tetrahymena. IV. Effect of dichloroisoproterenol on the intracellular source of released acid hydrolases. PMID- 4152224 TI - Confidentiality of medical records. PMID- 4152226 TI - A tool for innovative administration: management by objectives. PMID- 4152225 TI - Trustees, administration and medical staff interaction: a triangle for hospital management. PMID- 4152227 TI - Assessment and placement service: a key to successful bed utilization. PMID- 4152228 TI - Block scheduling of diagnostic services. PMID- 4152229 TI - APS: the Hamilton model. PMID- 4152230 TI - Pharmacare--a route to cheaper drugs. PMID- 4152231 TI - Editorial: Management of childhood asthma. PMID- 4152232 TI - [Cardiac glycosides and drugs used in anesthesia and resuscitation]. PMID- 4152233 TI - Lactoperoxidase-catalyzed iodination of chloroplast membranes. I. Analysis of surface-localized proteins. PMID- 4152234 TI - Accumulation of tyrosine hydroxylase molecules during growth and development of the superior cervical ganglion. PMID- 4152235 TI - Trophic functions of the neuron. II. Denervation and regulation of muscle. The use and abuse of muscle histochemistry. PMID- 4152236 TI - Trophic functions of the neuron. VI. Other trophic systems. The role of the nerve growth factor in the development of sensory and sympathetic ganglia. PMID- 4152237 TI - [Dental caries incidence in the teeth of adolescents in Moscow]. PMID- 4152238 TI - [Subcellular localization of tyrosine aminotransferase in the ox retina]. PMID- 4152239 TI - Amino acid flux and protein synthesis after exposure of rats to either Diplococcus pneumoniae or Salmonella typhimurium. AB - At 26 h after inoculation of rats with Diplococcus pneumoniae, the serum concentrations of 10 and 20 individual amino acids were lower than corresponding values observed in pair-fed controls. In contrast, only 2 of 20 serum amino acids were similarly decreased in rats inoculated with Salmonella typhimurium. Despite these serum differences, a greater accumulation of labeled non-metabolizable amino acids occurred in the livers of rats infected with S. typhimurium. These data suggested a greater increase in the flux of amino acids from muscle to liver in the rats infected with S. typhimurium as compared to those infected with D. pneumoniae. A similar increase in serum protein synthesis was observed in rats infected with D. pneumoniae or S. typhimurium. However, with the latter infection, a larger percentage of the amino acids appeared to be utilized as a source of energy in addition to their role as precursors of proteins. PMID- 4152240 TI - [Use of beta-adrenergic blocking agents in the therapy of cardiac arrhythmias]. PMID- 4152241 TI - The feasibility of an assistant to the physician. PMID- 4152242 TI - [Psycho-endocrine problems in a case of congenital adrenal hyperplasia diagnosed late]. PMID- 4152243 TI - [Continuous recording of the electrocardiogram in the diagnosis and treatment of dysrhythmia in children]. PMID- 4152244 TI - Effects of 8-azaguanine on the induction of uterine glucose-6-phosphate dehydrogenase activity by estradiol or NADP plus. PMID- 4152245 TI - Glutamine synthetase of Bacillus stearothermophilus. II. Regulation and thermostability. PMID- 4152246 TI - Human erythrocyte glucose 6-phosphate dehydrogenase. Content of bound coenzyme. PMID- 4152247 TI - Location of an isoproterenol-responsive cyclic AMP pool in adrenergic nerve cell bodies and its relationship to tyrosine 3-monooxygenase induction. AB - To decide whether adenosine 3':5'-cyclic monophosphate (cyclic AMP) plays a role as a second messenger in the trans-synaptic induction of tyrosine 3-monooxygenase (EC 1.14.16.2), it is desirable to discriminate between neuronal and extraneuronal changes in cyclic AMP concentration. Treatment of newborn rats with nerve growth factor antiserum or 6-hydroxydopamine, leading to destruction of 61 85% of the adrenergic nerve cell bodies in the superior cervical ganglion, led to a decrease in cyclic AMP of only 16-28%. This observation demonstrates that a relatively small portion of cyclic AMP is localized in the adrenergic neurons. However, administration of isoproterenol produced an increase (12-fold) in cyclic AMP only in this neuronal pool. Neither single nor repeated injections of isoproterenol led to induction of tyrosine monoxygenase. This, together with previous observations that experimental conditions leading to induction of the enzyme do not produce significant increases of cyclic AMP in the whole ganglion, is taken as an indication that cyclic AMP is not acting as a second messenger in the trans-synaptic induction of tyrosine monooxygenase in the rat superior cervical ganglion. In the rat adrenal medulla, treatment with reserpine led to both a shortlasting (60-90 min) increase in cyclic AMP and a subsequent induction of tyrosine monooxygenase. However, the increase in cyclic AMP was almost completely prevented (40 compared to 320%) by pretreatment of the rats with propranolol while the induction of tyrosine monooxygenase was not diminished. This observation also argues against an exclusive key-function of cyclic AMP in trans-synaptic induction of tyrosine monooxygenase in the adrenal medulla. PMID- 4152249 TI - Selection for neuroblastoma cells that synthesize certain transmitters. AB - A selection procedure was devised for neurons and related cells that depends upon the ability of the cells to synthesize certain amine neurotransmitters. The rationale for selection is that tyrosine is an essential amino acid for most mammalian cells and that three enzymes from mammalian sources can catalyze the synthesis of tyrosine: phenylalanine hydroxylase (EC 1.14.16.1), tyrosine hydroxylase (EC 1.14.16.2), and tryptophan hydroxylase (EC 1.14.16.4). Tyrosine hydroxylase is found predominantly in adrenergic neurons and related cells that synthesize dopamine, norepinephrine, and epinephrine, and tryptophan hydroxylase in cells synthesizing serotonin or melatonin. Only 1 out of 70,000 uncloned mouse neuroblastoma cells grew well in the absence of tyrosine. Approximately 50% of the cell lines obtained by selection had tyrosine hydroxylase activity. This selection procedure thus provides a simple means of obtaining cell lines of neural origin on the basis of their ability to synthesize putative transmitters. PMID- 4152248 TI - Glutathione synthetase deficiency, an inborn error of metabolism involving the gamma-glutamyl cycle in patients with 5-oxoprolinuria (pyroglutamic aciduria). AB - Enzyme studies on placenta, cultured skin fibroblasts, and erythrocytes from two sisters with the inborn error 5-oxoprolinuria (pyroglutamic aciduria) indicate that the metabolic lesion in this disease is at the glutathione synthetase (EC 6.3.2.3) step of the gamma-glutamyl cycle. Excessive urinary excretion of 5 oxoproline by these patients appears to be associated with increased synthesis of gamma-glutamyl-cysteine and formation of 5-oxoproline from this dipeptide. Thus, 5-oxoproline is produced in amounts that exceed the normal capacity of 5 oxoprolinase to convert it to glutamate. The data indicate that it may be possible to identify individuals who are heterozygous for this trait by determinations of erythrocyte glutathione synthetase. PMID- 4152250 TI - [Pharmacological basis of the symptomatic treatment of arterial hypertension. II. Antihypertensive agent combinations]. PMID- 4152252 TI - Histamine H2-receptors modulate systemic anaphylaxis: a dual cardiovascular action of histamine in calves. AB - Depressor changes in carotid blood pressure caused by histamine or anaphylaxis in calves, were incompletely blocked by the H(1)-receptor antagonist mepyramine. Burimamide, the selective histamine H(2)-receptor antagonist, potentiated the depressor actions of histamine and anaphylaxis. Potentiated depressor responses were inhibited by mepyramine. Observations are consistent with histamine stimulating both H(1)- and H(2)-receptors to cause respectively vasodilatation and vasoconstriction. PMID- 4152251 TI - A study of compounds which initiate and block nerve impulses in the perfused rabbit liver. AB - 1. A technique for the perfusion of the rabbit liver with Krebs solution is described: the hepatic nerves were monitored for centripetal action potentials. Spontaneous afferent activity, and a good response to stimulating agents persisted for 7 h or longer.2. Action potentials were elicited by injections or infusions of acetylcholine, 5-hydroxytryptamine, bradykinin, phenyldiguanide, adrenaline and various other compounds. From comparison with experiments carried out in vivo by other authors, it would appear that most of the nerves stimulated were afferent.3. Inhibition of action potentials, either those occurring spontaneously or those elicited by injections, was produced by aspirin, paracetamol, mepyramine, chlorpheniramine, procaine and lignocaine but not by morphine or atropine. Pentolinium produced some inhibition, as did hexamethonium in concentrations of about 7.5 mug/ml.4. Three methods for using the preparation for the assessment of local anaesthetic action are described.5. Lobeline, potassium cyanide and 2,4-dinitrophenol stimulated nerve bundles which were not stimulated by anoxia or hypoxia. PMID- 4152253 TI - Some effects of burimamide on the isolated perfused pulmonary circulation of the guinea-pig. AB - Infusions of burimamide were found to potentiate the pressor response to histamine and abolish the depressor response to histamine in the presence of mepyramine, in the isolated perfused guinea-pig pulmonary circulation. It is concluded that the depressor response to histamine is due to stimulation of histamine H(2)-receptors in the pulmonary vessels. PMID- 4152254 TI - The effects of a new alpha- and beta-adrenoceptor antagonist (AH5158) upon the general and coronary haemodynamics of intact dogs. AB - AH5158, a salicylamide derivative, said to be a blocker of alpha- and beta adrenoceptors, has been studied in intact anaesthetized dogs. At a dose of 2.5 mg/kg intravenously, the drug increased cardiac output and caused a late fall in mean systemic and pulmonary arterial pressure. Coronary sinus flow increased, as did cardiac oxygen extraction. External cardiac efficiency decreased. Blood glucose and non-esterified fatty acid values increased, but cardiac extraction of these did not change. PMID- 4152256 TI - Meningitis and bacteremia due to Haemophilus influenzae: occurrence and mortality at Boston City Hospital in 12 selected years, 1935-1972. PMID- 4152258 TI - [Diagnosis of periarteritis nodosa based on the angiographic picture]. PMID- 4152255 TI - Electron-microscopic heterogeneity of onion-bulb neuropathies of the Dejerine Sottas type. Two patients in one family with the variant described by Lyon (1969). PMID- 4152259 TI - Selective stimulation of a cellular immune response by methotrexate. PMID- 4152260 TI - Influence of disulfiram and sodium diethyldithiocarbamate on pressor response to tyramine in reserpinized rats. PMID- 4152261 TI - Effects of age and years of exposure on the economic benefits of fluoridation. PMID- 4152262 TI - Bacterial meningitis in Bernalillo County, New Mexico: a comparison with three other American populations. PMID- 4152263 TI - Vascular lesions in acute electric injuries. PMID- 4152264 TI - "Biogenic" aldehyde metabolism relation to pentose shunt activity in brain. PMID- 4152265 TI - Studies of the binding of sulfur released in the mixed-function oxidase-catalyzed metabolism of diethyl p-nitrophenyl phosphorothionate(parathion) to diethyl p nitrophenyl phosphate (paraoxon). PMID- 4152266 TI - [Possibility of identifying female mosquitoes (Culicidae) by microscopic preparations of the head. IV. A key to species of the genus Aedes]. PMID- 4152267 TI - [Value of isolated neuron cell culture in neurochemistry and neuropharmacology]. PMID- 4152268 TI - The effect of lipid phase transitions on the architecture of bacterial membranes. PMID- 4152269 TI - [Combined use of orthostatic and hyperventilation tests with beta-adrenergic blockage in the interpretation of primary electrocardiographic changes in the ventricular repolarization phase]. PMID- 4152270 TI - Prolonged survival in long-passage AKR leukemia using chemotherapy, radiotherapy, and adoptive immunotherapy. PMID- 4152271 TI - Collagenous sprue. PMID- 4152272 TI - Adenotonsillectomy as the treatment of serious medical conditions: five case reports. PMID- 4152273 TI - Abscesses of the head and neck. PMID- 4152274 TI - Trophic functions of the neuron. II. Denervation and regulation of muscle. The correlation of physiological properties with histochemical characteristics in single muscle units. PMID- 4152275 TI - [Tyrosine aminotransferase activity in various conditions of stress]. PMID- 4152276 TI - Mucociliary function of the respiratory tract as influenced by drugs. PMID- 4152277 TI - Physicians' fee schedule is a deterrent to quality care. PMID- 4152278 TI - [A patient dies: a physician is condemned: There is a bed shortage]. PMID- 4152279 TI - The European approach to food service. PMID- 4152280 TI - P.E.I. leads east coast hospitals: inservice education on team concepts. PMID- 4152281 TI - H.M.R.I. (Hospital Medical Record Institute)? P.A.S. (Professional Activity Study)? A comparison and evaluation of two automated systems. PMID- 4152282 TI - The "fatigue factor" in drug addiction: insufficient motivation for treatment. PMID- 4152283 TI - Phylogenetic distribution of opiate receptor binding. PMID- 4152284 TI - [Australia antigen and collagen diseases]. PMID- 4152285 TI - [Treatment of acute schizophrenic psychosis with beta-adrenergic blocking agents (author's transl)]. PMID- 4152286 TI - [Functional state of the adrenal cortex in congenital cryptorchism in children]. PMID- 4152287 TI - Lymphocyte deactivation by (potential immunosuppressant) alkylating metabolites of cyclophosphamide. PMID- 4152288 TI - [Topical application of fluoride varnish for dental caries prevention in collectives following a 3-year testing period]. PMID- 4152289 TI - Fibrosing alveolitis and treatment with sulphasalazine. AB - A woman with ulcerative colitis was treated with sulphasalazine and prednisolone. After four months' treatment she began to get short of breath and she died a month later with severe subacute fibrosing alveolitis. It is believed that the lung disease was caused by sulphasalazine and that prednisolone was not able to prevent its development. A reversible form of lung disease has previously been attributed to this drug. PMID- 4152292 TI - Sucrose taste sensitivity in Canadian Inuit and its relationship to dental caries. PMID- 4152291 TI - Mineral composition of normal human enamel and dentin and the relation of composition to dental caries. II. Microminerals. PMID- 4152290 TI - Mineral composition of normal human enamel and dentin and the relation of composition to dental caries. I. Macrominerals and comparison of methods of analyses. PMID- 4152293 TI - Secretor status and dental caries. PMID- 4152294 TI - The inhibitory effect of Ritodrine on human tubal activity in vivo. PMID- 4152295 TI - Amine-induced influence on spontaneous ovarian contractility in the guinea pig and the cat. PMID- 4152298 TI - Editorial: A proposal for marriage viewed with suspicion. PMID- 4152296 TI - Interaction of benzodiazepines with central nervous glycine receptors: possible mechanism of action. AB - Interaction of 21 benzodiazepines with the glycine receptor in the brainstem and spinal cord of rat have been evaluated in terms of their displacement of [(3)H]strychinine binding. The rank order of potency of the 21 drugs in displacing specific [(3)H]strychinine binding correlates (p < 0.005) with their rank order of potency in a vareity of pharmacological and behavioral tests in humans and animals that predict clinical efficacy. There is a 50-fold variation in potency of the series of benzodiazepines with mean effective dose (ED(50)) values ranging from 19muM to > 1000 muM. Diazepam (Valium(R)) and chlordiazepoxide (Librium(R)) have ED(50)'s of 26 muM and 200 muM, respectively, whereas the ED(50) for glycine is 25 muM. The inhibitory effects of 10 of the agents in two other central nervous system membrane receptor assays, for the opiate receptor and the muscarinic cholinergic receptor, do not correlate with any of the in vivo pharmacologic and behavioral tests. The benzodiazepines may exert their antianxiety, anticonvulsant and muscle-relaxant effects by mimicking the effects of the neurotransmitter glycine at its central nervous system receptor sites. PMID- 4152297 TI - The local graft versus host reaction in the rat as a tool for drug mechanism studies. AB - 1. A local graft versus host reaction in rats permits the evaluation of drug action on (i) donor (parental) animals and (ii) recipient animals (F(1) hybrid) prior to establishing a lymphoid cell graft to detect drugs which might attenuate immunocompetence over a prolonged period (e.g. steroids).2. Treatment of the recipient animals after a lymphoid graft readily detects anti-proliferative agents and may disclose other agents which interfere with the recognition of non self by viable graft cells.3. Treatment of the cell graft in vitro before innoculation into the recipient animal permits the detection of alkylating agents, which effectively deactivate graft cells at non-toxic concentrations.4. Examples are given of how this reaction may be used to evaluate functionally the effects of chemical modification of the cell surfaces of lymphocytes and to detect active metabolites generated from a precursor drug (e.g. cyclophosphamide).5. Some novel immunosuppressant drugs are described. PMID- 4152299 TI - Primary afferent depolarization: direct evidence in the trigeminal system. PMID- 4152300 TI - Causes of blindness in the world. Communication at the Budapest Congress. PMID- 4152301 TI - Field desorption mass spectra of antibiotics. PMID- 4152302 TI - [Periarteritis nodosa and infectious endocarditis]. PMID- 4152303 TI - [Use of extracorporeal circulation as a method of induction of tolerance during experimental heart transplantation]. PMID- 4152304 TI - Observations on the sporogonic cycle of Plasmodium berghei in two Australasian anophelines. PMID- 4152305 TI - An epidemic of chikungunya fever at Ibadan, Nigeria, 1969. PMID- 4152306 TI - Inheritance of susceptibility to Dirofilaria immitis infection in Aedes aegypti. PMID- 4152307 TI - Vascularization of porcine skin heterografts. PMID- 4152308 TI - Some new concepts in immunological phylogeny. PMID- 4152309 TI - Dissociation between effects of nerve growth factor on tyrosine hydrolase and tubulin synthesis in sympathetic ganglia. PMID- 4152310 TI - Heme-spin label studies of hemoglobin. II. Spin-labeled oxy- and deoxyhemoglobins. PMID- 4152311 TI - Genetic regulation of the catecholamine biosynthetic enzymes. II. Inheritance of tyrosine hydroxylase, dopamine-beta-hydroxylase, and phenylethanolamine N methyltransferase. PMID- 4152312 TI - Superoxide dismutase in the anaerobic flagellates, Tritrichomonas foetus and Monocercomonas sp. PMID- 4152313 TI - Studies on the effects of enantiomers of soterenol, trimetoquinol and salbutamol on beta adrenergic receptors of isolated guinea-pig atria and trachea. PMID- 4152314 TI - Cardiovascular actions of a new metabolite of propranolol: isopropylamine. PMID- 4152315 TI - Absence of degeneration of adrenergic neurons after prolonged treatment with debrisoquin. PMID- 4152316 TI - A role for nicotinic receptors in the regulation of the adenylate cyclase of adrenal medulla. PMID- 4152317 TI - A comparison of the effects of amphetamine and its metabolites, p hydroxyamphetamine and p-hydroxynorephedrine, on uptake, release and catabolism of 3H-norepinephrine in cerebral cortex of rat brain. PMID- 4152319 TI - Metabolic inhibitors and viral lymphomagenesis in thymic grafts. PMID- 4152318 TI - Biochemical properties of neoplastic cell mitochondria. PMID- 4152320 TI - In vitro effects of iodinated arthrographic contrast media on bacterial growth. PMID- 4152322 TI - Letter: Trojan Horse lymphocytes. PMID- 4152321 TI - The undifferentiated and extended forms of C1300 murine neuroblastoma. An ultrastructural study and detection of concanavalin A binding sites on the plasma membrane. AB - Mouse neuroblastoma cells (clone neuro-2A) in the undifferentiated and "differentiated" form were compared by light and electron microscopy. "Cytodifferentiation" was induced in monolayer cultures by the addition of dibutyryl-cyclic AMP. The pattern of concanavalin A binding sites was studied after coupling with horseradish peroxidase. The following major differences were observed. The differentiated cells are characterized by numerous and long neurites, aggregation of ribosomes into polysomes, an extensive network of neurofilaments and microtubules, many dense-core neurosecretory-like vesicles, a discontinuous pattern of concanavalin A binding sites on the plasma membrane, and an increase of the specific activities of acetylcholinesterase, choline acetylase and tyrosine hydroxylase. In contrast, the undifferentiated cells grown in suspension culture lack neurites, contain dispersed ribosomes, infrequent neurofilaments and microtubules and dense-core neurosecretory-like vesicles, and exhibit a continuous pattern of concanavalin A binding sites. In addition, the specific activities of the above mentioned enzymes are significantly lower. PMID- 4152324 TI - Normal histocompatibility antigens as a model for tumors. PMID- 4152325 TI - The complement system in necrotizing angiitis of the skin. Analysis of complement component activities in serum of patients with concomitant collagen-vascular diseases. PMID- 4152327 TI - The natural (and unnatural) history of hypertrophic obstructive cardiomyopathy. PMID- 4152326 TI - A comparison of enzyme-active membrane antigens from two different 4 dimethylaminoazobenzene-induced rat hepatomas with those of adult and fetal rat liver. PMID- 4152329 TI - Alpha-beta-adrenergic imbalance in intrinsic-intolerance rhinitis or asthma. PMID- 4152328 TI - Parenterally transmitted hepatitis A associated with platelet transfusions. Epidemiologic study of an outbreak in a marrow transplantation center. PMID- 4152330 TI - Letter: Beta-blockade in the presence of renal disease and hypertension. PMID- 4152331 TI - The effect of antilymphocytic antibody on the humoral immune response of different strains of mice. IV. Variable effect of individual ALG preparations on the immune response to type 3 polysaccharide antigen. PMID- 4152332 TI - An analysis of affinity chromatography using immobilised alkyl nucleotides. PMID- 4152333 TI - [Behaviour and properties of poliomyelitis coproantibodies using the "antiglobin test" and the conventional neutralisation test (author's transl)]. PMID- 4152334 TI - [Immuno-electrophoretic behaviour of antigen components of some Coxsackie viruses (author's transl)]. PMID- 4152335 TI - [The influence of electromagnetic waves on the course of an infection with Newcastle Disease virus in chick embryo tracheal organ cultures (author's transl)]. PMID- 4152336 TI - [On a bacteriophage-induced colanic acid depolymerase (author's transl)]. PMID- 4152337 TI - [Phosphatase measurements in pyogenic staphylococci of human and of bovine origin (author's transl)]. PMID- 4152338 TI - [Ten polyvalent Staphylococcus aureus phages--their range of action and their adaption to Staphylococcus albus (author's transl)]. PMID- 4152339 TI - [The initial phases of an infection by beta-hemolytic group A streptococci in the rabbit with special reference to streptodornase and antistreptodornase (author's transl)]. PMID- 4152340 TI - Sero-survey of Salmonella infection in man and animals by indirect haemagglutination test. PMID- 4152341 TI - [The biochemical differential diagnosis in the Klebsiella group (author's transl)]. PMID- 4152342 TI - [Effects of magnesium phosphates on the production of dyes by Pseudomonas aeruginosa (author's transl)]. PMID- 4152343 TI - Excretion of orally administered intestinal bacteria in humans. PMID- 4152344 TI - [Ring-shaped structures in Leptospirae (author's transl)]. PMID- 4152345 TI - Effect of variation in growth temperature on the biochemical activity and antigens of Mycobacterium marinum. PMID- 4152346 TI - [Effect of enterocin on Clostridium perfringens and Clostridium septicum (author's transl)]. PMID- 4152347 TI - Release of dipicolinic acid (DPA) from spores of Bacillus megaterium, B. stearothermophilus and B. anthracis in presence of bile acids. PMID- 4152348 TI - [The differenciation of avian mycoplasmas by means of disc-electrophoresis (author's transl)]. PMID- 4152349 TI - [The timing of treatment and post-mortem in the chemotherapy of experimental echinococcosis (author's transl)]. PMID- 4152350 TI - [The influence of sodium chloride and carbon dioxide on the growth of Neisseria meningitidis on nutrient agar (author's transl)]. PMID- 4152351 TI - [Growth and structure of cryptorchid testes in mice born of mothers treated by oestradiol during pregnancy (author's transl)]. PMID- 4152352 TI - Effect of early transplant function as an index of recipient presensitization on long-term function of machine-preserved cadaveric kidneys. PMID- 4152353 TI - Cryocurettage in the treatment of corneal ulcers: additional observations. PMID- 4152354 TI - Proceedings: Effect of histamine H2-receptor antagonists on gastric secretion, circulation, and acid-base-balance in cats. PMID- 4152355 TI - Proceedings: Effect of insulin on pyridinenucleotides in pancreatic islets. PMID- 4152356 TI - Proceedings: A simple screening method for the evaluation of beta-sympatholytics. PMID- 4152357 TI - Proceedings: The influence of steroids on microsomal NADH oxidation in rat liver and human placenta. PMID- 4152358 TI - Proceedings: Kinetics of distribution and elimination of a basic lipophilic drug metabolite in the rat. PMID- 4152360 TI - Proceedings: Glucose release of the rat kidney in vivo after beta-adrenergic stimulation and blockade. PMID- 4152359 TI - Proceedings: Influence of epoxide hydrase inhibitors on mutagenic effects of reactive metabolites generated in situ from benzo(a)pyrene. PMID- 4152361 TI - Proceedings: Non-specific cardiodepressant effects and hydrophobicity of two series of beta-adrenergic blocking drugs: influence of ring-alkylation and of n alkylation. PMID- 4152362 TI - Proceedings: Cyclic GMP formation in human platelets. PMID- 4152363 TI - Proceedings: Evidence for oxidative metabolism of metyrapone in rat liver microsomes. PMID- 4152364 TI - Proceedings: Combined effects of Lb46 resp. practolol and histamine on parameters of respiration and circulation in guinea pigs. PMID- 4152366 TI - Proceedings: Effect of serotonin on water intake and renin-angiotensin system in rats. PMID- 4152367 TI - Proceedings: Localization of alpha-adrenoceptors in the CNS with facilitatory effect upon vagal reflex cardioinhibition. PMID- 4152365 TI - Proceedings: Uptake of neurotransmitters into subcellular particles of the caudate nucleus. PMID- 4152368 TI - Proceedings: Clinical investigations on the chronic intoxication with bromocarbamides (carbromal and bromisoval). PMID- 4152369 TI - Proceedings: Influence of different metabolic conditions on the affinity of alpha and beta-sympathomimetic drugs on the rabbit aortic strip. PMID- 4152371 TI - Proceedings: Changes of the oxygen consumption in the heart muscle cell related to the heart rate and contraction force. PMID- 4152370 TI - Proceedings: Comparison of the inducing effect of halothane and ethrane in rat liver. PMID- 4152373 TI - Pathways of assimilation of dissolved organic matter by plankton organisms. PMID- 4152372 TI - Proceedings: Relationship between activity and structure in derivative of clonidine. PMID- 4152374 TI - [Diffuse interstitial pulmonary fibrosis in collagen diseases]. PMID- 4152375 TI - The role of gamma-aminobutyric acid as a mediator of positive dorsal root potentials. PMID- 4152376 TI - One thousand laparoscopies at a community hospital. PMID- 4152377 TI - On the nature of the adrenergic neuron extragranular amine binding site. PMID- 4152378 TI - [Induction of tyrosine aminotransferase in primary cultures of fetal rat liver. Inductor effects of steroids and dibutyryl cyclic AMP]. PMID- 4152380 TI - A comparison of the properties of membranes isolated from bovine skim milk and cream. PMID- 4152379 TI - [Energy conservation in the photosynthetic membrane of chloroplasts]. PMID- 4152381 TI - Malonate metabolism in rat brain mitochondria. PMID- 4152383 TI - [Exercise test in the evaluation of effectiveness of 4 antianginal drugs (author's transl)]. PMID- 4152382 TI - Studies on the mechanism of L-leucine-and alpha-ketoisocaproic acid-induced insulin release from perifused isolated pancreatic islets. PMID- 4152384 TI - A discussion on human adaptability in a tropical ecosystem an IPB human biological investigation of two New Guinea communities. Geographical, historical and social background of the peoples studied in the IBP. PMID- 4152385 TI - The demography of the population of Karkar Island. PMID- 4152386 TI - Movement, relatedness and the genetic structure of the population of Karkar Island. PMID- 4152387 TI - The hereditary blood factors of the peoples of New Guinea and the surrounding regions. PMID- 4152388 TI - Genetic distances between certain New Guinea population studied under the International Biological Programme. PMID- 4152389 TI - The occurrence of haemoglobin-J (Tongariki) and of thalassaemia on Karkar Island and the Papua New Guinea mainland. PMID- 4152390 TI - An anthropometric survey of growth and physique of the populations of Karkar Island and Lufa subdistrict, New Guinea. PMID- 4152391 TI - Karkar and Lufa: an epidemiological and health background to the human adaptability studies of the International Biological Programme. PMID- 4152392 TI - The energy and nutrient intake and the energy expenditure of 204 New Guinean adults. PMID- 4152393 TI - Lung function and the response to exercise in the New Guineans: role of genetic and environmental factors. PMID- 4152394 TI - Anthropometric and other factors affecting respiratory responses to carbon dioxide in New Guineans. PMID- 4152395 TI - A study of temperature regulation in New Guinea people. PMID- 4152396 TI - A field survey of thermal stress in New Guinea villagers. PMID- 4152397 TI - Why develop a conceptual framework? PMID- 4152398 TI - A practical evaluation of nursing care as part of the nursing process. PMID- 4152399 TI - Foundations of education for students and teachers of nursing. PMID- 4152400 TI - Organization of a family experience. PMID- 4152401 TI - The clinical instructor as role model. PMID- 4152402 TI - The book review: a significant educational resource. PMID- 4152404 TI - Investigation of H-2 and non-H-2 antigens on the mouse blastocyst. PMID- 4152403 TI - Nucleotides and nucleic acids. PMID- 4152405 TI - The effect of the RL-A locus and the NLC locus on graft survival in the rabbit. PMID- 4152406 TI - The structure of the stomatogastric neuromuscular system in Callinectes sapidus, Homarus americanus and Panulirus argus (Decapoda Crustacea). PMID- 4152407 TI - Safety and the American space program. PMID- 4152408 TI - Aircraft accident toxicology: U.K. experience 1967-1972. PMID- 4152410 TI - [Importance of health heredity control in the improvement of economics in pig breeding]. PMID- 4152409 TI - [Study of the monoamines in the extracephalic stomatogastric nervous system of Periplaneta americana]. PMID- 4152411 TI - [Regulation of NAD+ and NADP+ ferredoxin reductase activity in a Clostridium of the butyric group: Clostridium tyrobutyricum]. PMID- 4152412 TI - [Familial polyendocrine adenomatous hyperplasia syndrome]. PMID- 4152413 TI - [Associated pancreatic insular infiltrations. Insulinoma, gastrinoma, glucagonoma. Clinical, biological, and anatomo-pathological data]. PMID- 4152414 TI - [Pancreatic adenoma and polyendocrine pathology]. PMID- 4152415 TI - [Regulation of endocrine secretion in a case of polyadenomatosis]. PMID- 4152416 TI - Letter: The physician's assistant. PMID- 4152417 TI - Characteristics of the hydrogen bonding interactions of substituted hydantoins with 9-ethyladenine. PMID- 4152418 TI - Embryonal carcinoma. An unexpected cause of sudden death in a young adult. PMID- 4152420 TI - [Role of enzymatic phospholipid peroxidation in the mechanism of endoplasmic reticulum membrane uncoupling in vivo]. PMID- 4152419 TI - The action of certain drugs on the immediate contractile response of isolated guinea-pig detrusor muscle to X-irradiation. PMID- 4152421 TI - [Existence of a low-molecular factor, common to different molybdenum-containing enzymes]. PMID- 4152422 TI - Proceedings: Evolutionary aspects of transmitter heterogeneity. PMID- 4152423 TI - Proceedings: GABA as a transmitter in the central nervous system of vertebrates. PMID- 4152424 TI - Oxidation of barbiturates and the glucuronidation of 1-napthol in perfused rat liver and in microsomes. PMID- 4152425 TI - Chemical studies on individual neurons. II. Invertebrate nerve cells. PMID- 4152426 TI - Response augmentation and blockade in cholinergic neuromuscular tissues. PMID- 4152427 TI - What is the functional role of central nervous serotonin? PMID- 4152428 TI - Chemical correlates of neural function. PMID- 4152429 TI - A combined neurochemical and neurophysiological approach to identification of central nervous system transmitters. PMID- 4152431 TI - Learning and use of knowledge. PMID- 4152430 TI - Psychophysics of excitation and tranquilization from a steady-state perspective. PMID- 4152432 TI - Classifications and terminology of psychotropic drugs. A historical critical review. PMID- 4152433 TI - Growth of stem cell concentration in diffusion chambers (DC). PMID- 4152434 TI - [Diagnostic procedure in bradycardia]. PMID- 4152435 TI - [Effects of various adrenergic beta receptor blockers on hypertensive reflexes induced by the stimulation of neural afferences]. PMID- 4152436 TI - Theoretical models for heterogeneity of base composition in DNA. PMID- 4152437 TI - [Mosquitoes and transmission of viral hepatitis]. PMID- 4152438 TI - [Skin allotransplantation simultaneously with heart allotransplantation]. PMID- 4152439 TI - Pneumococcal spinal subdural abscess (a case report). PMID- 4152440 TI - Perceptual memory for numerousness in "nonpsychotic schizophrenics". PMID- 4152442 TI - [Trial of an alpha-blocking agent in the treatment of thyrotoxicosis]. PMID- 4152441 TI - [Physio-pharmacology of coronary insufficiency. I]. PMID- 4152443 TI - [Evaluation of the action of bamethan on some respiratory function parameters and the pulmonary circulation]. PMID- 4152444 TI - [Therapy of dyspnea]. PMID- 4152445 TI - MMPI scores for field-dependent and field-independent psychiatric outpatients. PMID- 4152446 TI - Behavioral correlates of single-scale MMPI code types. PMID- 4152447 TI - Motivation-hygiene correlates of mental health: an examination of motivational inversion in a clinical population. PMID- 4152448 TI - [Psychopharmalogical study of a central alpha-sympathomimetic agent, xylazine analgesic and tranquillizer in veterinary medicine]. PMID- 4152449 TI - [Anti-histaminic activity of fumarine]. PMID- 4152451 TI - Swimming instruction for pre-school children. PMID- 4152450 TI - Mechanism of bacterial transformation and transfection. PMID- 4152452 TI - The cholesterol hypothesis and the coronary primary prevention trial. PMID- 4152453 TI - Rupture of the heart. Report of a case with one week survival. PMID- 4152454 TI - Categorization of hospital emergency medical capabilities in Illinois: A statewide experience. PMID- 4152455 TI - Hemangiosarcoma of breast. PMID- 4152456 TI - The view box. PMID- 4152457 TI - EKG of the month. PMID- 4152458 TI - The changing role of neonatal nursing. PMID- 4152459 TI - Editorial: Angina pectoris. PMID- 4152460 TI - [Surgical risk in relationship to iatrogenic medication]. PMID- 4152462 TI - Educational programs for surgeon's assistants. PMID- 4152461 TI - [Current use and future prospects of monitoring systems and intensive therapy in Greast Britain]. PMID- 4152463 TI - Essentials of an approved educational program for the surgeon's assistant. PMID- 4152464 TI - Division is perilous. PMID- 4152466 TI - [Study on the distribution of the coefficient of prevalence of dental caries (CPC)]. PMID- 4152465 TI - [Influencing of the circulation rate and oxygen metabolism in the ischemic myocardium. Comparison with the effect on the normal myocardium]. PMID- 4152467 TI - [Acute renal insufficiency of vascular origin]. PMID- 4152468 TI - Studies on the structure and function of the mammalian testis. V. Steroid metabolism by isolated interstitium and seminiferous tubules of the human testis. PMID- 4152469 TI - A quantitative study of the fixation of acid phosphatase by formaldehyde and its relevance to histochemistry. PMID- 4152470 TI - The structure of a high density lipoprotein (HDL3) from porcine plasma. PMID- 4152471 TI - Spermiogenesis of Eledone cirrhosa Lamarck (Cephalopoda, Octopoda). PMID- 4152472 TI - [Crohn's disease (author's transl)]. PMID- 4152473 TI - [Pre- and intra-operative care of pheochromocytoma]. PMID- 4152474 TI - [Neurohumoral regulation of liver function]. PMID- 4152475 TI - [Bioluminescence (author's transl)]. PMID- 4152477 TI - The public health or community nurse--her duties and responsibilities in the new health service. PMID- 4152476 TI - Synthesis and bioassays of a new dimethoxyalkylmercapto-1,4-benzoquinones. PMID- 4152478 TI - [Effect of glucose and other carbon sources on formation of respiratory enzymes in yeast cells (author's transl)]. PMID- 4152479 TI - Tenth International Leprosy Congress Bergen, 1973. Reports of committees. PMID- 4152480 TI - Pneumonia caused by a pneumococcus resistant to erythromycin and lincomycin. Case report. PMID- 4152482 TI - Congress highlights and reflections. PMID- 4152481 TI - X-ray of the month. PMID- 4152483 TI - [Effect of beta-stimulating and beta-blocking drugs on alveolar surfactant activity]. PMID- 4152484 TI - On the regulation of tryptophan hydroxylase in brain. PMID- 4152485 TI - 5-Methoxytryptamine: a possible central nervous system transmitter. PMID- 4152486 TI - [Fixation of the anti-LH-RF antibody at the level of the posterior pituitary gland of the toad Bufo vulgaris Laur]. PMID- 4152487 TI - [Mexican mosquitoes. Current geographic distribution]. PMID- 4152488 TI - Heat dyscontrol syndrome in patients receiving antipsychotic, antidepressant and antiparkinson drug therapy. PMID- 4152489 TI - [Mechanism of action of psychotropic drugs]. PMID- 4152490 TI - [Gamma-glutamyl-transpeptidase (gamma-GT), a liver test?]. PMID- 4152491 TI - Association of oral microorganisms plaque, diet and dental caries in students. PMID- 4152492 TI - [Epidemiological study of dental caries in a school population in Strasbourg]. PMID- 4152493 TI - [Gold alloy solders. 3. Physical properties]. PMID- 4152494 TI - [Brinell hardness of gold alloys]. PMID- 4152495 TI - [Time interval since last dental visit by dental students]. PMID- 4152496 TI - It's your committee and it's your future. PMID- 4152497 TI - Clinical variations of cystic fibrosis. PMID- 4152498 TI - Electrical alternans. Case report and comments on its mechanism and diagnostic significance. PMID- 4152499 TI - Treating psoriasis of the scalp with a new corticosteroid lotion. PMID- 4152500 TI - Lithium carbonate in the treatment of manic-depressive disorders: a follow up study. PMID- 4152501 TI - Speech therapy for the mildly dysphasic patient: when is it indicated? PMID- 4152502 TI - Abdominal wall abscess in an infant. PMID- 4152503 TI - Rediscovery of Cushing's forceps. PMID- 4152504 TI - Rape. PMID- 4152505 TI - Surgical grand rounds: Hyperparathyroidism and pregnancy. PMID- 4152506 TI - Epigastric pain and vomiting with or without a history of trauma. PMID- 4152507 TI - The role of the social worker in the Community Hospital. PMID- 4152508 TI - [Reaction time method in the study of performance in patients with cerebral lesions]. PMID- 4152509 TI - "What do you think of the concept of physician assistants? Would you ever use one? Why, or why not?". PMID- 4152511 TI - [Periarteritis nodosa]. PMID- 4152510 TI - Recent advances in the pathophysiology of asthma. PMID- 4152513 TI - [Enamelite. 1st positive experience with the use of composites]. PMID- 4152512 TI - [Role of feldsher health centers in the prevention of injuries in mines]. PMID- 4152514 TI - [A new profession: social medicine assistant]. PMID- 4152515 TI - [The Stockholm conference on the human environment]. PMID- 4152516 TI - [Symposium on anti-arrhythmic drugs of the Swedish Society of Cardiology]. PMID- 4152517 TI - [Preliminary study on the effect of a nicergoline composition (F.I. 6714) on cerebral blood flow]. PMID- 4152518 TI - Federation Dentaire Internationale Chronicle of the 61st Annual Session Sydney, Australia, 15th--20th July 1973. PMID- 4152519 TI - Impaired drug metabolism in rats with adjuvant-induced arthritis: a brief review. PMID- 4152520 TI - [Pterin chemistry. 46. Identification of substituted tetrahydropterins through gas chromatography and mass spectrometry]. PMID- 4152521 TI - [New development in the study of infectious hepatitis]. PMID- 4152522 TI - New developments in glucose-6-phosphate dehydrogenase deficiency. PMID- 4152523 TI - [Analysis of the therapeutic effect of the lumbar sympathectomy in obliterating arterial diseases of the limbs]. PMID- 4152524 TI - General analgesia and anesthesia in obstetrics. PMID- 4152525 TI - Subcellular constituents of human placenta. II. Isolation and density distribution of lysosomes from first trimester tissue. PMID- 4152526 TI - [Maternal and infant mortality in the Federal Republic of Germany. 6th German Congress on Perinatal Medicine, November 28-December 2, 1973, Berlin-West]. PMID- 4152527 TI - The gamma-glutamyl cycle. Diseases associated with specific enzyme deficiencies. PMID- 4152528 TI - Inhibition of rat liver mitochondrial oxidative phosphorylation by sulfobromophthalein. PMID- 4152529 TI - Effects of alpha-adrenergic blocking agents on narcotic-induced analgesia. PMID- 4152530 TI - Functional recovery after lesions of the nervous system. IV. Structural correlates of recovery in adult subjects. Changes in drug sensitivity during recovery of function after brain damage. PMID- 4152531 TI - History of the Illinois Medical Journal. PMID- 4152532 TI - Oldest living Illinois physician: the remarkable Dr. Hill. PMID- 4152533 TI - Personal dedications guide physicians. The oath of Hippocrates. PMID- 4152534 TI - Neuromuscular dysfunctions of the external urinary sphincter. PMID- 4152535 TI - Studies on cryptorchidism: a comparison of histological findings in the germinative epithelium before and after the second year of life. PMID- 4152536 TI - An ADN approach to the open curriculum. PMID- 4152537 TI - The reappearance of immunologically reactive lymphocytes following termination of homograft tolerance. PMID- 4152538 TI - The response of homograft-tolerant rats to allogeneic lymphocytes. PMID- 4152539 TI - Tolerance induction to a heterotopic cardiac allograft in the irradiated reconstituted mouse. PMID- 4152540 TI - Studies of various amphetamines, apomorphine and clonidine on body temperature and brain 5-hydroxytryptamine metabolism in rats. PMID- 4152541 TI - Lithium and alpha-methyl-p-tyrosine prevent "manic" activity in rodents. PMID- 4152542 TI - Chromosomal anomalies and central nervous system. PMID- 4152543 TI - [Haemodynamic study of septic shock. Apropos of 26 cases]. PMID- 4152544 TI - [Ambulatory treatment of chronic coronary insufficiency]. PMID- 4152545 TI - The differentiation pathway of T lymphocytes. Evidence for two differentiated cell types. AB - Two experimental models have been used to study T-cell differentiation. The first, a graft-vs.-host reaction, was induced by injecting thymocytes or cortisone-resistant thymocytes into lethally irradiated allogeneic mice. The second was tumor graft rejection in allogeneic hosts. Ultrastructural studies at various time intervals revealed two differentiated T-cell types. One of these (the "pale" cell) is probably high cytotoxic as measured in the chromium-release assay, the other (the "dark" cell) may be an "amplifier" cell, helping in the differentiation of cytotoxic cells. PMID- 4152546 TI - Sites of metyrapone inhibition of steroid biosynthesis by rat adrenal mitochondria. PMID- 4152548 TI - [Main topics of discussion at the conference of representatives of the 4. Congress of the Dental Society of the German Democractic Republic]. PMID- 4152547 TI - Guanosine cyclic 3',5'-monophosphate and guanylate cyclase activity in guinea pig lung: effects of acetylcholine and cholinesterase inhibitors. PMID- 4152549 TI - [Relationships between the thyroid and parathyroid]. PMID- 4152550 TI - [Conclusions of the meeting of the Belgian Society for the Scientific Study of Tuberculosis and Pneumology in Lanaken (author's transl)]. PMID- 4152551 TI - Brain 5-hydroxytryptamine and cyclic AMP in morphine tolerance and dependence. PMID- 4152552 TI - Measurements of monoamine synthesis and turnover with special reference to 5 hydroxytryptamine. PMID- 4152553 TI - Prospects and predictions for the cardiomyopathies. PMID- 4152554 TI - Biotransformation of fluroxene. PMID- 4152555 TI - Hepatic metabolism of halothane. PMID- 4152556 TI - Biotransformation of trichloroethylene. PMID- 4152557 TI - A sample survey of dental knowledge, attitudes, behavior and needs among Scott County school children. I. The dental inspection. PMID- 4152558 TI - Acetyl coenzyme A carboxylase. Subunit structure of the protomeric form of the avian liver enzyme. PMID- 4152559 TI - Reaction mechanism of ribonucleoside diphosphate reductase from Escherichia coli. Oxidation-reduction-active disulfides in the B1 subunit. PMID- 4152560 TI - A simplified assay for coenzyme M (HSCH2CH2SO3). Resolution of methylcobalamin coenzyme M methyltransferase and use of sodium borohydride. PMID- 4152561 TI - Endo-beta-N-acetylglucosaminidase acting on carbohydrate moieties of glycoproteins. Purification and properties of the enzyme from Diplococcus pneumoniae. PMID- 4152562 TI - Functional compartmentation of acetaldehyde oxidation in rat liver. PMID- 4152564 TI - [Psychological investigations (MMPI) in non-psychiatric out-patients (author's transl)]. PMID- 4152563 TI - The use of psychotropic agents in heart disease. PMID- 4152565 TI - Is the representation of the objective body-image in figure drawings related to the personality characteristics of the drawer? PMID- 4152566 TI - Profile stability of a clinical rating scale. PMID- 4152567 TI - [Immunosuppressive agents]. PMID- 4152568 TI - [Psychosomatic correlations in women with ulcer disease]. PMID- 4152569 TI - Improved patient care. PMID- 4152570 TI - Operating room assistants program. PMID- 4152571 TI - Butaperazine dimaleate metabolism. PMID- 4152572 TI - The interaction of the antineoplastic drug thalicarpine with aniline hydroxylase and microsomal cytochrome of rat liver. PMID- 4152573 TI - Mosquitoes: a public health threat in Arizona? PMID- 4152574 TI - Enzyme organization in the proline biosynthetic pathway of Escherichia coli. PMID- 4152575 TI - An electron microscopic and autoradiographic study of mesogleal organization and collagen synthesis in the sea anemone Aiptasia diaphana. PMID- 4152576 TI - Effects of pipothiazine palmitate on CNS structures: neurophysiological and behavioral and behavioral correlations. PMID- 4152577 TI - [Analysis of the dental status of quadruplets in Hungary]. PMID- 4152578 TI - Pitfalls in histochemical localization studies of NADPH generating enzymes or enzyme systems in rat small intestine. PMID- 4152579 TI - Evidence obtained by cathepsin digestion of microsomes for the assembly of cytochrome b5 and its reductase in the membrane. PMID- 4152580 TI - Induction of tyrosine aminotransaminase and ornithine decarboxylase in isolated perfused regenerating rat liver. PMID- 4152581 TI - Effect of quasi-substrate on the monomer-dimer equilibrium of D-amino acid oxidase. PMID- 4152583 TI - Free autologous composite tendon grafts for division of both flexor tendons within the digital theca of the hand. PMID- 4152582 TI - Partial purification of a carbon monoxide-binding hemoprotein reconstitutively active in fatty acid omega-hydroxylation from porcine kidney cortex microsomes. PMID- 4152584 TI - Comparison of the MMPI and the Mini-Mult with alcoholics. PMID- 4152585 TI - The permeability to water of the cuticle of the larva of Opifex fuscus (Hutton) (Diptera, Culicidae). PMID- 4152586 TI - Size and distribution of histochemical fibre types in masseter muscle of adults with different states of occlusion. PMID- 4152587 TI - Dipsogenic action of diazoxide: a pharmacologic analysis. PMID- 4152588 TI - Control of norepinephrine synthesis in blood vessels and the effects of monoamine oxidase inhibition. PMID- 4152589 TI - Variation of intra- and perisynaptic adrenergic transmitter concentrations with width of synaptic cleft in vascular tissue. PMID- 4152590 TI - Metiamide, an H2-receptor blocker, as inhibitor of basal and meal-stimulated gastric acid secretion in patients with duodenal ulcer. PMID- 4152591 TI - Editorial: Unrefined antihistamine lode. PMID- 4152592 TI - Estimation of the rate of 5-HT synthesis in the mouse brain by various methods. PMID- 4152593 TI - Characterization of the adrenoceptors mediating the positive ino- and chronotropic effect of phenylephrine on isolated atria from guinea pigs and rabbits by means of adrenolytic drugs. PMID- 4152594 TI - Structure and assembly of bacterial surface layers composed of regular arrays of subunits. PMID- 4152601 TI - Discriminative response control by d-amphetamine and related compounds in the rat. PMID- 4152602 TI - Glucose-6-phosphate dehydrogenase Toulouse. A new variant with marked instability and severe deficiency discovered in a family of Mediterranean ancestry. PMID- 4152603 TI - Riboflavin and drug metabolism in adult male and female rats. PMID- 4152604 TI - The interaction of 2-phenylisatogen and menadione with rat liver mitochondrial NADH dehydrogenase. PMID- 4152605 TI - The nicotinamide nucleotide specificity of glutamate dehydrogenase in intact rat liver mitochondria. PMID- 4152606 TI - Intranuclear and intermicrosomal distributions of 3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase in rat ventral prostate. PMID- 4152607 TI - Corticosteroidogenic responsiveness to adrenocorticotropin and dibutyryl cyclic AMP in isolated adrenal cells of hypophysectomized rats. PMID- 4152608 TI - Transformation of testosterone into 17beta-hydroxy-5beta-androstan-3-one by Rana esculenta skeletal muscle. PMID- 4152609 TI - Pigeon liver diacetyl reductase: purification and some properties. PMID- 4152610 TI - Mitochondrial acetaldehyde dehydrogenase from Saccharomyces cerevisiae. PMID- 4152611 TI - Purification and properties of glutamine synthetase from Bacillus stearothermophilus. PMID- 4152612 TI - Evidence for a specific phosphatidyl inositol transferring protein in rat brain. PMID- 4152613 TI - The effect of lesions of ascending noradrenaline pathways on sleep and waking in the rat. PMID- 4152614 TI - Inhibition of the regenerative growth of central noradrenergic neurons by intracerebrally administered anti-NGF serum. PMID- 4152617 TI - Glycosidases of marine invertebrates from Posiet Bay, Sea of Japan. PMID- 4152619 TI - In virto adsorption of bile salts to food residues, salicylazosulfapyridine, and hemicellulose. PMID- 4152620 TI - Central atropine-like toxicity in combined psychotropic drug administration. PMID- 4152621 TI - [Development of mortality in malignant neoplasms of the respiratory tract]. PMID- 4152622 TI - [Drug-induced damage of the liver]. PMID- 4152624 TI - [Will the computer be used in life insurance medicine?]. PMID- 4152623 TI - [Evaluation of physical capacity in breathing disorders]. PMID- 4152625 TI - Hydroperoxide peroxidase activity in liver microsomes. PMID- 4152627 TI - [Proceedings: Orthostatic syndrome]. PMID- 4152626 TI - Immune function and dysfunction in relation to aging. PMID- 4152628 TI - Brain monoamines. Biosynthesis and fate. PMID- 4152629 TI - Interpretation of effects of lesions on localization of brain monoamines. PMID- 4152630 TI - The pediatrician in community dental health. PMID- 4152631 TI - Structure-activity studies on the gamma-glutamyl cycle and its relationship to amino acid transport. PMID- 4152632 TI - 'Piggyback' chromatography: assay for guanylate cyclase in retina and other neural tissue. PMID- 4152633 TI - "First-pass" metabolism of paracetamol in rat liver. PMID- 4152634 TI - [A low-molecular rotenone-like acting inhibitor of the NADH oxidase system in cauliflower buds (Brassica oleracea L.)]. PMID- 4152635 TI - [A natural anti-allergic principle in bile]. PMID- 4152636 TI - [A privilege is not a right]. PMID- 4152637 TI - [Abnormalites of left ventricular function during angina]. PMID- 4152638 TI - [Action of respiratory inhibitors on mitochondrial respiratory enzymes in cauliflower (Brassica oleracea L.)]. PMID- 4152639 TI - [Activity of hexosemonophosphate shunt enzymes at different stages of the mitotic cycle of Ehrlich tumor cells]. PMID- 4152640 TI - [Adrenoreceptor activity and noradrenaline content in rat tissues]. PMID- 4152641 TI - [Antiarrhythmic action of penbutolol]. PMID- 4152642 TI - [Apropos of the article on the various phases of periarteritis nodosa of C. Betourne and others]. PMID- 4152643 TI - [Beta adrenolytic activity and hemodynamic effects of penbutolol]. PMID- 4152644 TI - [Can Neisseria meningitidis still proliferate at 25 degrees C? (author's transl)]. PMID- 4152646 TI - [Catecholamines and adrenergic receptors]. PMID- 4152645 TI - [Capillaria hepatica infection of Mastomys natalensis: alterations of enzyme activities in serum (author's transl)]. PMID- 4152647 TI - [Characteristic sport injuries of track and field athletes]. PMID- 4152648 TI - [Clinical and pathological study on polyarteritis nodosa like vascular lesion in systemic lupus erythematosus (author's transl)]. PMID- 4152649 TI - [Clinical aspects of dissecting aneurysm of the thoracic aorta (author's transl)]. PMID- 4152651 TI - [Clinical study on the use of SB 5833 (Camazepam) in general medicine]. PMID- 4152650 TI - [Clinical experimetation with Piracetam]. PMID- 4152652 TI - [Comparative researches of learning tracking tasks with fixed, quasi-fixed and adaptively changing difficulty level. I. Middle learning improvement--reliability -antagonism learning-fatigue (author's transl)]. PMID- 4152653 TI - [Cryptococcoma and amphotericin B therapy of cryptococcosis-animal experiments. 1. Microbiological results (author's transl)]. PMID- 4152654 TI - [Cryptorchism]. PMID- 4152655 TI - [Cumulative dosage study on the effect of NAB 365 and fenoterol on the values of pulmonary function, blood pressure, pulse rate and general tolerance]. PMID- 4152656 TI - [Current data on the lateral biochemical effects of dopa]. PMID- 4152657 TI - [Current problems in active substance research. 4. Central effects of angiotensin II]. PMID- 4152658 TI - [Current problems of active substance research. 3. Structure-activity relationships of angiotensin II and analog]. PMID- 4152659 TI - [Cytochrome absorption spectra of bacteria as aid for solving taxonomic problems. 1. Elaboration and description of a method for measuring the redox and carbon monoxide difference spectra of suspensions of intact live bacterial cells (author's transl)]. PMID- 4152660 TI - [Cytochrome absorption spectra of bacteria as aid for solving taxonomic problems. 2. The redox and carbon monoxide difference spectra of bacterial species of the families Enterobacteriaceae, and Pasteurellaceae, and of the genera Aeromomas, Xanthomonas, Vibrio, Acinetobacter, Alcaligenes, and Achromobacter (author's transl)]. PMID- 4152661 TI - [Dental caries prevention in Zagreb schoolchildren from 1968-1973]. PMID- 4152662 TI - [Differential spectrophotometry in the quantitative determination of cyclodol, ridinol and piridrol]. PMID- 4152663 TI - [Doping]. PMID- 4152664 TI - [Drug therapy of arteriosclerotic circulatory disorders]. PMID- 4152665 TI - [Effect of a combination of vasoactive substances on the metabolism and the rheoencephalogram]. PMID- 4152666 TI - [Effect of adrenaline derivatives on the isolated tracheal muscle of guinea pigs]. PMID- 4152667 TI - [Effect of cinnarizine (Stutgeron) on cell proliferation caused by hypertension, in the heart and aorta in animal experiments]. PMID- 4152668 TI - [Effect of guanethidine on capillary permeability]. PMID- 4152670 TI - [Effect of PGE1, PGE2 and PF2alpha prostaglandins on vascular permeability in rats]. PMID- 4152669 TI - [Effect of L-dopa on the duodenal motility of the dog]. PMID- 4152671 TI - [Effects of adrenaline derivatives on the heart-lung preparation of the dog]. PMID- 4152672 TI - [Electron microscopic study on the heart muscle of rats after application of a beta-stimulating sympathicomimetic (NAB 365)]. PMID- 4152673 TI - [Energy status of the brain and drugs]. PMID- 4152674 TI - [Enhanced activity of Pseudomonas aeruginosa phages by adaptation to and modification in a host cell. I. Choice of a suitable combination of phage and bacterial strain (author's transl)]. PMID- 4152676 TI - [Epidemiological aspects of dental caries in white and non-white school children of both sexes in 7 orphanages of the city of Sao Paulo, Brazil, in 1972]. PMID- 4152675 TI - [Enzymology of the cornea. I. Biochemistry]. PMID- 4152677 TI - [Ethers and esters of 4-(2-hydroxyethyl)-imidazole and esters of 4 imidazolepropionic acid. IV. Structure-activity relationship of histamanine analogs]. PMID- 4152678 TI - [Experimental study of the activity of the sulphamethoxypyrazine (Longum equals Kelfizina) with pyrimethamine (Daraprim) on the cysts development phase of Toxoplasma gondii in Mastomys natalensis. Further contribution to experimental chemotherapy of toxoplasmosis (author's transl)]. PMID- 4152679 TI - [Extractive volumetric determination of Dithiaden, Methiaden and Prothiaden using sodium lauryl sulfate]. PMID- 4152681 TI - [Gamma-glutamyl transpeptidase. 1. The mechanism of its increase in the serum]. PMID- 4152680 TI - [Functional and enzymatic activities of blood granulocytes in patients with monoclonal serum immunoglobulin]. PMID- 4152682 TI - [Gamma-glutamyl transpeptidase. 2. The clinical evaluation of serum gamma glutamyl transpeptidase in hepatobiliary disease]. PMID- 4152684 TI - [Glucagonoma]. PMID- 4152683 TI - [General principles of antihypertensive treatment]. PMID- 4152685 TI - [Histochemical study of normal, denervated, self and cross-reinnervated anterior and posterior latissimus dorsi muscles of the chicken]. PMID- 4152686 TI - [Histoenzymological exploration of the hypothalamus]. PMID- 4152687 TI - [Immunosuppressive treatment of skin diseases. I. Action of immunosuppressive drugs]. PMID- 4152688 TI - [Ipecac sirup]. PMID- 4152689 TI - [Kinetic properties of the glutamine synthetase of Candida tropicalis yeasts in the transferase reaction]. PMID- 4152690 TI - [Laboratory methods and organizational aspects of serological tests for syphilis in the light of discussions at the International Round Table Conference]. PMID- 4152691 TI - [Letter: Injections by physician's assistants]. PMID- 4152692 TI - [Letter: Normal gamma-glutamyl transpeptidase in hepatitis]. PMID- 4152693 TI - [Liquid-solid high pressure chromatography. Separation and determination of phenothiazine derivatives with neuroleptic activity]. PMID- 4152694 TI - [Liver function tests (author's transl)]. PMID- 4152695 TI - [Longitudinal studies on the metabolite pattern of perazine and related phenothiazines in human and animal]. PMID- 4152696 TI - [Marine medicine]. PMID- 4152697 TI - [Microbiological evaluation of a new synthetic cephalosporin, cephapirin (author's transl)]. PMID- 4152699 TI - [New auxiliary and professional personnel of factory physicians, their education and continuing education--ideas and bases for discussion]. PMID- 4152698 TI - [Neuropathy associated with Australia antigen and periarteritis nodosa. Apropos of the viro-immunological origin of a collagen disease (3 cases, among these 2 anatomoclinical cases)]. PMID- 4152700 TI - [New reports on automatic textprocessing at the International Congress of Radiology in Madrid, October 1973 (author's transl)]. PMID- 4152701 TI - [Non-hemoglobin iron in erythrocytes]. PMID- 4152702 TI - [Ocular lesions caused by phenothiazines]. PMID- 4152703 TI - [Oral hygiene survey of navy recruits]. PMID- 4152704 TI - [Pharmacological and biochemical approach to a syndrome of action and intention myoclonus in the course of degenerative disease of the nervous system]. PMID- 4152705 TI - [Pharmacological aspects of cerebral hemodynamics]. PMID- 4152706 TI - [Physical changes in a bismuth oxychloride suspension induced by exogenous influence (author's transl)]. PMID- 4152707 TI - [Physiology of ovulation]. PMID- 4152708 TI - [Premedication and general anesthesia in stomatologic practice]. PMID- 4152709 TI - [Presence of the genus Lactobacillus (Beijerinck) in the human stomach (author's transl)]. PMID- 4152710 TI - [Present-day state and perspectives of the development of roentgenology and radiology (materials of the 13th International Congress of of World Association of Roentgenologists and Radiologists)]. PMID- 4152711 TI - [Proceedings: Neurochemical and neurophysiological bases of the action of psychopharmaceutic agents]. PMID- 4152712 TI - [Protective effect of stem-bromelain in combination with antibiotics on experimental infection in mice induced by Streptococcus hemolyticus, Diplococcus pneumoniae, or Pseudomonas aeruginosa (author's transl)]. PMID- 4152713 TI - [Psychological characteristics and physiological reactions to stress in normal and coronary subjects]. PMID- 4152714 TI - [Psychopharmaceutics and the heart]. PMID- 4152715 TI - [Pulmonary function tests on the bronchospasmolytic effects of the beta-2 adrenergics: salbutamol, terbutaline and NAB 365 (double placebo experiment)]. PMID- 4152716 TI - [Rating of psychological effects induced by "ordinary" Noveril and time-released Noveril (author's transl)]. PMID- 4152717 TI - [Report of the Congress]. PMID- 4152718 TI - [Report on 3 new cases of hereditary enzymopenic methemoglobinemia]. PMID- 4152719 TI - [Role of sympathetic nerve system and skeletal muscles in theophylline-induced thermogenesis. Studies on non-shivering thermogenesis. 2 (author's transl)]. PMID- 4152720 TI - [Round-table conference. Problems of drug addiction and alcoholism]. PMID- 4152721 TI - [Size of the left ventricular volume. Methods and results in the assessment of left ventricular performance]. PMID- 4152722 TI - [Soldering in dentistry]. PMID- 4152723 TI - [Some pharmacologic properties of mono-(O-beta-hydroxyethyl)-7-rutoside in the rat]. PMID- 4152724 TI - [Structure-activity relationship of analeptics of the nicethamide type. 1. Diethylamide of homologous and vinylogs of nicotinic acid and isonicotinic acid]. PMID- 4152725 TI - [Studies on alcoholic liver injury. II. Effect of alcohol intake on serum gamma glutamyltranspeptidase activity in man (author's transl)]. PMID- 4152726 TI - [Studies on the modification of purine metabolism through azathioprine]. PMID- 4152727 TI - [Studies on tryptophan metabolism in oligophrenic children. 2. Vitamin-dependent enzyme patterns (B1, B2, B6) and excretion of the tryptophan metabolites kynurenin, xanthurenic acid, trigonellinamide, and N-methylpyridone]. PMID- 4152728 TI - [Study of hemodynamic effects of acetoxy-thymoxy-ethyl-dimethylamine]. PMID- 4152729 TI - [Study, in the dog, of effect of alpha and beta blocking agents on arterial pressure effects of L-Dopa]. PMID- 4152730 TI - [Symposium: "Automatic processing of radiologic findings"]. PMID- 4152731 TI - [The antibody production against the antigens C and D of Coxsackie virus, investigated by means of acetate foil electrophoresis (author's transl)]. PMID- 4152732 TI - [The effect of Mycobacterium bovis BCG-Praha on the growth of Daels' guinea-pig sarcoma (author's transl)]. PMID- 4152733 TI - [The faecal flora of man. II. The composition of bifidobacterium flora of different age groups (author's transl)]. PMID- 4152734 TI - [The most used indexes in preventive dentistry]. PMID- 4152735 TI - [The radioimmunoassay in the solid phase for the detection of hepatitis B antigen in blood donors and hepatitis patients (author's transl)]. PMID- 4152736 TI - [The various phases of periarteritis nodosa]. PMID- 4152737 TI - [Theoretical and practical aspects of uterine contractility inhibition]. PMID- 4152738 TI - [Therapy of cryptochism]. PMID- 4152739 TI - [Thriving cooperative medical service]. PMID- 4152740 TI - [Treatment of angina pectoris with beta-blocking agents]. PMID- 4152741 TI - [Treatment of lichen ruber]. PMID- 4152742 TI - [Treatment of ulcerative colitis]. PMID- 4152743 TI - A comparison between the personality changes in certain forms of psychomotor and grand-mal epilepsy. PMID- 4152744 TI - A comparison of antibiotic-sterilized, stent-mounted pulmonary and aortic valve allografts in the mitral region of dogs. PMID- 4152745 TI - A comparison of the inhibitory effects of certain antiparkinsonian agents on dopamine accumulation into the rat striatum. PMID- 4152746 TI - A hostility scale for form R of the MMPI. PMID- 4152747 TI - A new method for detection of causative agents at various sites of air way in patients with respiratory infection. PMID- 4152748 TI - A new variant of glucose-6-phosphate dehydrogenase deficiency hereditary hemolytic anemia, G6PD Cornell: erythrocyte, leukocyte, and platelet studies. PMID- 4152749 TI - A nicotinamide-adenine dinucleotide assay utilizing liver alcohol dehydrogenase. PMID- 4152750 TI - A preliminary clinical trial of Prazosin: a new oral antihypertensive agent. PMID- 4152751 TI - A role for the pyridine nitrogen of reduced triphosphopyridine-nucleotide in the mechanism of action of isocitrate dehydrogenase. PMID- 4152752 TI - A study of drug metabolism linked to cytochrome P-450 in isolated rat-liver cells. PMID- 4152753 TI - A study of patient populations in New York City tropical disease clinics. PMID- 4152754 TI - A survey of neuroendocrine phenomena in non-arthropod invertebrates. PMID- 4152755 TI - A 3(17)beta-hydroxysteroid dehydrogenase in raterythrocytes. Conversion of 5alpha dihydrotestosterone into 5alpha-androstane-3beta,17beta-diol and purification of the enzyme by affinity chromatography. PMID- 4152756 TI - Accumulation and tissue distribution of mercury in the guinea pig during subacute administration of methyl mercury. PMID- 4152757 TI - Action of clonidine on baroreceptor reflexes in conscious dogs. PMID- 4152758 TI - Actions of atropine, hemicholinium-3, and physostigmine on chlorpromazine-induced changes in rat brain monoamines. PMID- 4152759 TI - Activation of hexose monophosphate pathway in brain by electrical stimulation in vitro. PMID- 4152760 TI - Activity of adrenal catecholamine-producing enzymes and their regulation after stress. PMID- 4152761 TI - Activity of gamma-glutamyl transpeptidase and other enzymes in the serum of sheep with liver or kidney damage. PMID- 4152762 TI - Acute and chronic morphine treatment and the hydroxylation of (1-14C)-L-tyrosine in the mouse brain. AB - Tyrosine hydroxylase activity in slices of caudate nucleus was increased by morphine (100 mg/kg i.p.) administered to naive mice. During chronic treatment with morphine tolerance developed to this effect and 36 h after the final chronic morphine injection there was a decrease in enzyme activity in this area. There was no change in tyrosine hydroxylase activity in slices of diencephalon, brainstem or parietal cortex from either naive or morphine tolerant mice. There- fore, changes in tyrosine hydroxylase activity, measured in vitro, could account for the changes in dopamine synthesis, but not noradrenaline synthesis, produced by morphine in vivo. PMID- 4152763 TI - Acute epiglottitis. A surgical emergency. PMID- 4152764 TI - Aerobic and anaerobic glycolysis in the liver after hemorrhage. PMID- 4152766 TI - Alcoholism--a general hospital meets the challenge. PMID- 4152765 TI - Age differences in the baroreceptor response of rats. PMID- 4152767 TI - All in a day's work: the case for ambulatory surgery. PMID- 4152768 TI - Altered norepinephrine synthesis of splanchnic vessels in neurogenic hypertension. PMID- 4152769 TI - Amino acid aminotransferase activity of rat heart. PMID- 4152770 TI - Ammonia detoxifying mechanisms of rainbow trout altered by dietary dieldrin. PMID- 4152771 TI - An appraisal of the functional significance of the inhibitory effect of long chain acyl-CoAs on mitochondrial transports. PMID- 4152773 TI - An experimental model of hormone dependent immunodeficiency disease. PMID- 4152772 TI - An electron microscope autoradiographic study of the neuronal and extraneuronal localization of labeled amine in the heart of the bat after administration of tritiated norepinephrine. AB - The localization of labeled amine in the heart of the bat after administration of tritiated norepinephrine (NE) was studied by means of electron microscope autoradiography. Monoamine oxidase was inhibited so that the distribution of amine in both neuronal (Uptake(1)) and extraneuronal (Uptake(2)) sites could be analyzed. Labeling was nonrandom in both the atrial and ventricular myocardium. The highest relative specific activity was found in neural processes which showed morphological criteria of terminal adrenergic axons. Analysis of the distribution of label around the labeled axonal varicosities indicated that the radioactive amine was more concentrated peripherally than centrally in these structures. Label was also found over cardiocytes in both atrium and ventricle. The pattern of this labeling indicated that the radioactive amine was associated with myofilaments. In the ventricle, I bands were most heavily labeled, indicating a probable association of radioactive amine with thin filaments. Labeling was prevented by administration of phenoxybenzamine and decreased only in cardiocytes by normetanephrine. The nonrandom distribution of labeled amine within cardiocytes supports the view that Uptake(2) represents not only a second mechanism of inactivation of the sympathetic neurotransmitter, but may also be involved in the mediation of some of the action of NE on cardiac muscle. PMID- 4152774 TI - An improved procedure for the enzymatic analysis of prostaglandins in the nanogram range. PMID- 4152775 TI - An inhibitory innervation at the gastroduodenal junction. AB - Transverse muscle strips, 2-mm wide, were cut serially from the gastroduodenal junction in opossums, cats, dogs, and man. Electrical field stimulation with trains of rectangular current pulses of 0.5 ms in all opossums, all cats, some dogs, and the one human specimen induced relaxation in strips from the thickened circular muscle proximal to the mucosal junction. In some opossums weak relaxations also occurred in the first few strips below the mucosal junction. All other strips contracted or showed no response. This relaxation in opossums was abolished by tetrodotoxin but was not affected by antagonists to adrenergic and cholinergic transmission, nor by tripelennamine, methysergide, pentagastrin, secretin, cerulein, or cholecystokinin. Optimal frequency for stimulus-relaxation was 12 Hz. Chronaxie was 0.85 ms. The junctional strips also showed greater resistances to stretch than those remote from the junction. With apparent species variations, the junctional muscle possesses a nonadrenergic inhibitory innervation which is either absent or unexpressed in adjacent muscle of stomach and duodenum. This suggests the existence of a distinctive inhibitory neural control mechanism for pyloric muscle. PMID- 4152777 TI - Analgesia produced by clonidine in mice and rats. PMID- 4152776 TI - An investigation of the relationship between beta-adrenoceptor blockade and plasma practolol concentration in man. PMID- 4152778 TI - Anesthetic interaction with a model cell membrane: expansion, phase transition, and melting of the lecithin monolayer. PMID- 4152779 TI - Antagonistic effects of apomorphine and haloperidol on rat striatal synaptosomal tyrosine hydroxylase. PMID- 4152781 TI - Anti-lymphocytic antibodies and marrow transplantation. 3. Effect of heterologous anti-brain antibodies on acute secondary disease in mice. PMID- 4152780 TI - Anti-inflammatory property of 401 (MCD-peptide), a peptide from the venom of the bee Apis mellifera (L.). AB - 1 Peptide 401, a potent mast cell degranulating factor from bee venom, substantially inhibited the oedema provoked by subplantar injection of carrageenin or intra-articular injection of turpentine in the rat. The ED(50) of 401 was c. 0.1 mg/kg. The anti-inflammatory effect was assessed by measurement of the increased (125)I-albumin content of an injected site in comparison with an uninjected contralateral site.2 Peptide 401 also suppressed the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, bradykinin, 5-hydroxytryptamine (5-HT), and prostaglandins).3 Other comparable mast cell degranulating agents (48/80 and melittin) showed little evidence of anti-inflammatory activity when tested at comparable dosage on turpentine arthritis and carrageenin oedema.4 The anti inflammatory effects were not abolished by pretreatment with mepyramine and methysergide, which abolished the increased vascular permeability produced by local injection of 401.5 The anti-inflammatory action of 401 was not affected by regional denervation or pretreatment with phenoxybenzamine, and was reduced but not abolished by adrenalectomy.6 Measurement of skin temperature, fractional extraction of (86)Rb and blood flow in perfused mesentery gave no evidence that the anti-inflammatory action of 401 was due to reduced tissue perfusion.7 It is concluded that 401 may exert its anti-inflammatory action directly by making the vascular endothelium anergic to phlogistic stimuli. PMID- 4152783 TI - Application of orthogonal functions to spectrophotometric analysis. The combined polynomial method. PMID- 4152784 TI - Application of Viega's simplified indices for estimating the prevalence of dental caries in Thai children. PMID- 4152785 TI - Aspects of chronic low back pain. PMID- 4152782 TI - Antiasthmatic drugs I: pathophysiological and clinical pharmacological aspects. PMID- 4152786 TI - Assays for narcotic antagonist activity in rodents. PMID- 4152787 TI - Association between increase in cyclic AMP and subsequent induction of tyrosine hydroxylase in rat adrenal medulla. Experiments with swimming stress. PMID- 4152788 TI - Bacteriophage-induced ribonucleotide reductase systems. T5- and T6-specific ribonucleotide reductase and thioredoxin. PMID- 4152789 TI - Bamethan A competitive betamimetic drug. PMID- 4152790 TI - Beta adrenergic and anti-arrhythmic effects of cardiopep, a newly isolated substance from whole bee venom. PMID- 4152791 TI - Beta cell monoamines: further evidence for their role in modulating insulin secretion. PMID- 4152792 TI - Beta-adrenergic blockade and sensitivity to exogenous histamine in bronchial asthma. PMID- 4152794 TI - Biological properties of the nerve growth factor. PMID- 4152793 TI - Biochemical mapping of noradrenergic nerves arising from the rat locus coeruleus. PMID- 4152795 TI - Biosynthesis of adrenal catecholamines during adaptation of rats to immobilization stress. PMID- 4152796 TI - Blockade by burimamide of the effects of histamine and histamine analogues on cardiac adenylate cyclase. PMID- 4152797 TI - Bluetongue and related viruses in Ibadan, Nigeria: isolation and preliminary identification of viruses. PMID- 4152798 TI - Bone-marrow transplantation in combined immunodeficiency disease. PMID- 4152799 TI - Brain and liver intracellular compartmental redox states in hypoxia, hypocapnia and hypercapnia. PMID- 4152800 TI - Capsular types and outcome of bacteremic pneumococcal disease in the antibiotic era. PMID- 4152801 TI - Carbon-monoxide oxidation in cell-free extracts of Clostridium pasteurianum. PMID- 4152802 TI - Cardiac stimulant action of extracts of coelenterates on rat atria. PMID- 4152803 TI - Cardiovascular beta-adrenergic receptor blocking activities of 1-(7-indenyloxy)-3 isopropyl-aminopropane-2-ol hydrochloride (YB-2) and its optical isomers. PMID- 4152804 TI - Cardiovascular stimulant responses following intravenous administration of MJ 9465-2 (2-amino-4-(4-chlorophenyl)-2-imidazoline-HBr) in the dog: mechanisms of action. PMID- 4152805 TI - Central hypothermia by 2-deoxy-D-glucose: antagonism by alpha-adrenergic activation. PMID- 4152806 TI - Changes in beta-adrenoceptor-blocking activity produced by chemical modifications in the practolol molecule. PMID- 4152808 TI - Characteristics of B cell tolerance induced with T-independent polysaccharides. PMID- 4152807 TI - Characteristics of transmitter release at regenerating frog neuromuscular junctions. AB - 1. A study was made of the onset of transmission and the characteristics of transmitter release from regenerating nerve terminals in frog muscle fibres.2. Soon after transmission had been restored, some junctions were found which responded to nerve stimulation with only subthreshold end-plate potentials.3. The evoked transmitter release had a non-linear dependence on the external calcium concentration, like that seen at normal junctions.4. The synaptic delay was only slightly longer than normal, and the amplitudes of single quantum potentials evoked by nerve stimulation seemed to have a normal distribution.5. The mean amplitude of the spontaneous miniature end-plate potentials was often substantially smaller than the mean amplitude of the evoked quantal potentials at a given end-plate. Some of these small spontaneous potentials were due to transmitter release from the axon terminal. Possible explanations for this discrepancy in size of spontaneous and evoked potentials are discussed. Two to three weeks after reinnervation began, the amplitude of the spontaneous miniature end-plate potentials returned to normal. PMID- 4152809 TI - Characterization of Salmonella typhimurium strains sensitive and resistant to methionine sulfoximine. AB - Methionine sulfoximine inhibits the growth of Salmonella typhimurium at a concentration of 50 muM, and the addition of glutamine, but not glutamate, is sufficient to overcome this inhibition. The analogue causes 50% inhibition of glutamine synthetase activity at 2 to 4 muM and of glutamate synthase at 2 to 3 mM when these enzymes are assayed in vitro. No inhibition of glutamate dehydrogenase activity is observed at analogue concentrations as high as 50 mM. Two mutants selected for their resistance to methionine sulfoximine inhibition have a partial growth requirement for glutamine and a reduction in the glutamine synthetase and glutamate synthase activities. The sensitivity of the remaining glutamine synthetase activity in these mutants to methionine sulfoximine inhibition appears unaltered, and the lesions conferring the analogue resistance may not affect glutamine synthetase directly. PMID- 4152810 TI - Chemical messengers in development: a hypothesis. AB - The hypothesis that physiological and developmental regulatory mechanisms are similar has been presented. Well-known developmental systems chosen illustrate the capability of the model to suggest a simple mechanism underlying the effects on development of a diverse group of chemicals. This hypothesis might be applied to other systems including the induction of the lens, limb regeneration, and the induction of the head of hydra (124). I have proposed this hypothesis not only because it permits consideration of a complex and varied array of experimental observations as reflections of a simple basic biochemical mechanism, but because recent technical advances in instrumentation and methods allow it to be directly tested. The fluorescent antibody method for the cytochemical measurement of cyclic nucleotides provides a means for investigating changes in the concentrations of cyclic nucleotides in developing cells and could also be used to detect neurotransmitters in developing cells. Similarly, the scanning electron microscope in the emitted x-ray mode provides a method for measuring changes in the content and distribution of cations within developing cells. The hypothesis presented here suggests pleasing asceticism on the part of eukaryotes. It suggests that simple derivatives of metabolites, including neurotransmitters and cyclic nucleotides, are linked together as regulatory molecules throughout the eukaryotes. The neurotransmitters are suggested to have a more general role in information transmission in eukaryotes than is generally accepted. They are hypothesized to have progressed during evolution from being intracellular messengers to a role as intercellular messengers for the relatively slow communication of developmental informatbn; and, finally, this process has culminated with their participation in the rapid intercellular communication mediated by nerves. The thought that the complex pictures of physiological regulation and of the construction of a complex multicellular organism like man might be painted with so few colors is quite satisfying. PMID- 4152812 TI - Clinical trial of a new beta-receptor blocking agent, tolamolol, in angina pectoris. PMID- 4152811 TI - Chloroplast structure and function. A report of the British Photobiology Society meeting held in London on 19 October 1973. PMID- 4152813 TI - Comparative evaluation of injectable chlorpromazine and piperacetazine. PMID- 4152815 TI - Comparative physiology of hemorrhage. A study of adrenergic receptor stimulation and blockade in pigeon and mammal. PMID- 4152814 TI - Comparative involvement of dopamine and noradrenaline in rate-free self stimulation in substania nigra, lateral hypothalamus, and mesencephalic central gray. PMID- 4152816 TI - Compartmentation of dopamine in rat striatum. PMID- 4152817 TI - Compression characteristics of powders: radial die wall pressure transmission and density changes. PMID- 4152819 TI - Correlates of accuracy in personality assessment. PMID- 4152818 TI - Control of organ blood flow following hemorrhage. PMID- 4152820 TI - Covariance of myocardial cyclic AMP and calcium during beta-adrenergic stimulation in vivo. PMID- 4152821 TI - Critical period for the development of spontaneous hypertension in rats. PMID- 4152823 TI - Cyclic nucleotides and smooth muscle. PMID- 4152822 TI - Cyclic nucleotide metabolism in normal and proliferating epidermis. PMID- 4152824 TI - Cyclorphan and related compounds. PMID- 4152825 TI - Cytochrome P-450 difference spectra. Type II interactions in insecticide resistant and -susceptible houseflies. PMID- 4152827 TI - Deafness and acupuncture. PMID- 4152826 TI - Cytochrome P-450 difference spectra: effect of chemical structure on type II spectra in mouse hepatic microsomes. PMID- 4152828 TI - Defferentiation between the "critical period," the "activation period" and the "potential activation period" for neurohumoral stimulation of LH release in proestrous rats. PMID- 4152830 TI - Delayed hypersensitivity and essential hypertension. Delayed hypersensitivity against arterial wall components as a pathogenetic factor in essential hypertension. PMID- 4152829 TI - Degeneration secretion of saliva in the rat following sympathectomy. AB - 1. After previous extirpation of the superior cervical ganglion saliva was found to flow from the cannulated submaxillary duct of rats under chloralose anaesthesia. The secretion started 13-14.5 hr after sympathectomy, increased gradually in rate and then slowed down and ceased, lasting for about 12 hr.2. Injection of alpha- or beta-adrenoreceptor blocking drugs reduced the flow and a combination of both types of drugs abolished it. It is concluded that the secretion was caused by noradrenaline released from the degenerating nerves, and that the phenomenon is an example of the degeneration activity described in other preparations as an effect of section of post-ganglionic autonomic nerves.3. A similar, but less pronounced, secretion was found in the parotid gland of the rat. PMID- 4152831 TI - Dental caries prevalence in seven soil areas of New Zealand. PMID- 4152832 TI - Dental caries-experience in three generations of families. PMID- 4152833 TI - Dental health of junior dental students. PMID- 4152834 TI - Dental health of migrant agricultural workers. PMID- 4152835 TI - Depression and hostility. PMID- 4152836 TI - Differences in the cardiac and pressor responses to propranolol of rats and guinea pigs. PMID- 4152837 TI - Different types of immunological unresponsiveness. PMID- 4152838 TI - Differential spectrophotometric determination of phenylephrine in eye-drops: the deltaAr method. PMID- 4152839 TI - Distinct subpopulations of thymus-dependent lymphocytes. Tracing of the differentiation pathway of T cells by use of preparatively electrophoretically separated mouse lymphocytes. PMID- 4152840 TI - Distribution of exogenous acetaldehyde in cow adrenal medulla chromaffin granules. PMID- 4152841 TI - Distribution of marker enzymes between mesosomal and protoplast membranes. PMID- 4152842 TI - Double-blind study in psychopathic behavior disorders (clozapine and pericyazine). PMID- 4152843 TI - Drug therapy reviews. Rational use of psychotropic drugs. I. Hypnotics. PMID- 4152844 TI - Editorial: The new orchestration. PMID- 4152845 TI - Effect of acetaldehyde on the isolated, non-working guinea-pig heart: independence of the coronary flow increase from changes in heart rate and oxygen consumption. PMID- 4152846 TI - Effect of adrenergic activation on collateral coronary blood flow. PMID- 4152847 TI - Effect of alpha-adrenergic blockers on naloxone-binding in brain. PMID- 4152848 TI - Effect of hemorrhagic shock on gluconeogenesis, oxygen consumption and redox state of perfused rat liver. PMID- 4152849 TI - Effect of lipid peroxidation and its inhibitors (BHA, BHT) on the drug metabolizing enzymes in rat liver microsomes. PMID- 4152850 TI - Effect of phenothiazine neuroleptic drugs and tricyclic antidepressants on phosphodiesterase activity in rat cerebral cortex. PMID- 4152851 TI - Effect of protein-free diet on mitotic activity of transplanted splenic lymphocytes. PMID- 4152852 TI - Effect of reserpine on catechol-O-methyl transferase in rat submaxillary gland. PMID- 4152853 TI - Effect of serum albumin upon the response of the rat isolated superfused anococcygeus muscle to catecholamines and to nerve stimulation. PMID- 4152854 TI - Effect of single and repeated administration of clozapine on the metabolism of dopamine and noradrenaline in the brain of the rat. PMID- 4152855 TI - Effective hospital management through the corporate structure. PMID- 4152856 TI - Effects of a bacteriocin produced by Streptococcus faecalis var. zymogenes (E1) on susceptible microorganisms. PMID- 4152857 TI - Effects of alpha- and beta-receptor blockade on systolic time intervals. PMID- 4152858 TI - Effects of burimamide, an antagonist of H-2 histamine receptors, in the gastric fistula dog. PMID- 4152859 TI - Effects of catecholamines, exercise, and nitroglycerin on the normal and ischemic myocardium in conscious dogs. AB - The effects of isoproterenol, norepinephrine, dobutamine, exercise, and nitroglycerin on left ventricular diameter, pressure, velocity of shortening, dP/dt, dP/dt/P, arterial pressure, left circumflex coronary blood flow, and coronary vascular resistance were examined in healthy conscious dogs with normal coronary perfusion and in the same animals after moderate global ischemia had been induced by partial occlusion of the left main coronary artery. In the normal nonischemic heart, all interventions improved left ventricular performance, as evidenced by increases in dP/dt/P and velocity at the same or lower left ventricular end-diastolic diameter. Interventions, which in the normal heart caused large increases in heart rate and myocardial contractility, e.g. isoproterenol and exercise, or which decreased coronary perfusion pressure, e.g. nitroglycerin or isoproterenol, elicited paradoxical responses in moderate global ischemia, i.e., left ventricular enddiastolic diameter and pressure rose, and dP/dt/P and velocity fell substantially. On the other hand, norepinephrine, which increased coronary perfusion pressure along with myocardial contractility but did not increase heart rate, improved left ventricular function. Dobutamine, which did not alter heart rate or arterial pressure substantially while improving myocardial contractility, produced an intermediate response between that of norepinephrine and isoproterenol in the presence of moderate global myocardial ischemia. Thus, interventions that increase myocardial O(2) requirements, by increasing heart rate and myocardial contractility without augmenting coronary perfusion pressure, can produce a paradoxical depression of ventricular function in the presence of global myocardial ischemia. PMID- 4152860 TI - Effects of chronic nicotine administration and age on various neurotransmitters and associated enzymes in male Fischer-344 rats. PMID- 4152861 TI - Effects of dopamine on the superior cervical ganglion of the rabbit. AB - 1. The effects of dopamine on isolated rabbit superior cervical ganglion were investigated with intracellular recording techniques.2. Dopamine (10(-5)-10(-3)M) depressed the amplitude of the excitatory post-synaptic potential (e.p.s.p.) and blocked impulse transmission.3. Dopamine (10(-4)M) induced a slight (2-5 mV) post synaptic hyperpolarization without altering membrane conductance.4. The post synaptic membrane sensitivity to acetylcholine (ACh) applied iontophoretically was not affected by dopamine.5. Dopamine decreased the frequency of miniature excitatory post-synaptic potentials (m.e.p.s.p.s) in a high K(+) solution, with no change in the amplitude of m.e.p.s.p.s.6. Dopamine reduced the quantal content of the e.p.s.p. in a low Ca(2+) and high Mg(2+) solution, but had no effect on the quantal size.7. The ganglionic blocking effect of dopamine was antagonized by phenoxybenzamine, but not by propranolol.8. The results show that the ganglionic depressant effect of dopamine is exerted primarily through an alpha-adrenoceptive site at the presynaptic nerve terminal. PMID- 4152862 TI - Effects of local anesthetics, antihistamines, and glucocorticoids on peripheral blood flow and vascular smooth muscle. PMID- 4152863 TI - Effects of noradrenaline pump blockers on its uptake by synaptosomes from several brain regions; additional evidence for dopamine terminals in the frontal cortex. PMID- 4152864 TI - Effects of single doses of alprenolol and two cardioselective beta-blockers (H 87 07 and H 93-26) on exercise-induced angina pectoris. PMID- 4152865 TI - Effects of tetraphenylboron (TPB) on the autonomic nervous system. PMID- 4152866 TI - Effects of the optical isomers of the narcotic antagonist analgesic pentazocine on brain and heart biogenic amines. PMID- 4152868 TI - Effects of 2,4-dinitrophenol and N,N'-dicyclohexylcarbodiimide on cell envelope associated enzymes of Escherichia coli and Salmonella enteritidis. PMID- 4152867 TI - Effects of Gymnodinium breve toxin on the smooth muscle preparation of guinea-pig ileum. AB - 1 The effects of Gymnodinium breve neurotoxin (GT) on smooth muscles were studied using the guinea-pig isolated ileum.2 The toxin caused strong spasmogenic effects at 1-4 mug/ml, characterized by prolonged tonic contraction with superimposed pronounced pendular movements. Tachyphylaxis was observed upon administration of successive doses.3 Atropine blocked the contractile response elicited by GT, whereas mepyramine and hexamethonium failed to do so. These findings tentatively suggested a cholinergic involvement at a post-ganglionic site of action.4 In the presence of tetrodotoxin the effects of GT were abolished, excluding direct action of the toxin on the smooth muscle.5 It is concluded that GT exerts its spasmogenic effects through stimulation of the post-ganglionic cholinergic nerve fibres. PMID- 4152869 TI - Efflux of prostaglandins in right lymphatic duct lymph following induced intravascular coagulation and inhibited fibrinolysis in the dog. PMID- 4152870 TI - Elevated acetylcholine contents in mouse brain after treatment with bicuculline and picrotoxin. PMID- 4152871 TI - Enzymatic catalysis of the reversible sulfitolysis of glutathione disulfide and the biological reduction of thiosulfate esters. PMID- 4152872 TI - Enzymatic conjugation of foreign chemical compounds by rabbit lung and liver. PMID- 4152873 TI - Enzymatic reduction of 5-deazariboflavine from reduced nicotinamide adenine dinucleotide by direct hydrogen transfer. PMID- 4152874 TI - Enzyme assays at the single cell level using a new type of microfluorimeter. PMID- 4152875 TI - Enzyme of polymorphisms of erythrocytes in psoriasis. PMID- 4152876 TI - Enzymes of the gamma-glutamyl cycle in the choroid plexus and brain. PMID- 4152877 TI - Enzymes of the homogentisate ring-cleavage pathway in cell suspension cultures of higher plants. PMID- 4152878 TI - Ergot alkaloids and some problems of the physiology of their formation. PMID- 4152879 TI - Evidence for direct alpha-adrenoceptor stimulation of effector neurons in cardiovascular centers by clonidine. PMID- 4152880 TI - Evidence for extranoradrenergic dopamine-beta-hydroxylase activity in rat salivary gland. PMID- 4152881 TI - Evidence for redistribution of filtrate among nephrons after beta-adrenergic stimulation and blockade. PMID- 4152882 TI - Experimental studies on facilitative and inhibitory factors for epileptogenic focus formation. PMID- 4152883 TI - Factors influencing observed beta-adrenergic receptor antagonism in guinea-pig trachea. PMID- 4152884 TI - Feedback inhibition of glutamine synthetase from green pea seeds. PMID- 4152885 TI - First international congress. World Federation of Neurological Nurses. PMID- 4152886 TI - First prison admissions with juvenile histories and absolute first offenders: frequencies and MMPI profiles. PMID- 4152887 TI - Fluorinated tryptophans as substrates and inhibitors of the ATP--(32P)PPi exchange reaction catalysed by tryptophanyl tRNA synthetase. PMID- 4152888 TI - Formation and metabolism in vitro of 5,6-epoxides of cholesterol and beta sitosterol. AB - The formation of 5alpha,6alpha- and 5beta,6beta-epoxides of cholesterol and beta sitosterol in rat liver subcellular fractions has been studied. The results show that the epoxidation seems to occur only in connection with the nonspecific tissue oxidation of the sterols. The beta-epoxides were formed in three- to fourfold excess over the alpha-epoxides. Both cholesterol epoxides were efficiently converted by a microsomal hydrolase into the 3beta,5alpha,6beta triol. The conversion was less extensive with beta-sitosterol epoxides, especially the beta-epoxide. The possible biological significance in the formation of the sterol epoxides and the triols was evaluated by their ability to inhibit the microsomal cholesterol 7alpha-hydroxylase. Only the cholesterol epoxides and especially the beta-epoxide were active in this respect. PMID- 4152889 TI - Functional and structural proteins of the nervous system. PMID- 4152890 TI - Functional significance of neuronal and extraneuronal transmitter uptake in rat salivary glands. The effect of protriptyline and normetanephrine. PMID- 4152891 TI - Future trends in ambulatory short-stay surgery. PMID- 4152892 TI - Glucose-6-phosphate dehydrogenase from Caulobacter crescentus. PMID- 4152893 TI - Glutamate dehydrogenase of Tetrahymena. PMID- 4152894 TI - Growth of Venezuelan encephalitis virus and disapperance of coxsackie A, Rous sarcoma, herpes simplex and vaccinia viruses following inoculation of Aedes aegypti and other mosquitoes. PMID- 4152896 TI - Help-seeking attitudes and severity of psychological distress. PMID- 4152895 TI - Guanyl cyclase in chick embryo brain cell cultures: evidence of neuronal localization. PMID- 4152897 TI - Hepatic microsomal ethanol-oxidizing system: solubilization, isolation, and characterization. PMID- 4152898 TI - Hepatitis B antigen in urban-caught mosquitoes. PMID- 4152899 TI - High-affinity uptake of (3H)gamma-aminobutyric acid into frog spinal cord slices. PMID- 4152900 TI - Histological and histochemical changes in the jejunal mucosa in ulcerative colitis. PMID- 4152901 TI - Host preference in Aedes (Stegomyia) mosquitoes in Uganda. II. Studies on indoor and outdoor biting and resting behaviour with special reference to Aedes aegypti L. PMID- 4152902 TI - Hydroxymethylation of the benzene ring. Microsomal hydroxymethylation of benzo(alpha)pyrene to 6-hydroxymethylbenzo(alpha)pyrene. PMID- 4152903 TI - Hypertensive encephalopathy: Mechanisms, clinical features, and treatment. PMID- 4152904 TI - Identification of the major enzymic activities of the mitochondrial inner membrane in terms of their migration in sodium dodecyl sulfate polyacrylamide gel electrophoresis. PMID- 4152905 TI - Imidazole and penicilloylation in penicillin allergy. PMID- 4152906 TI - Immune response to pneumococcal polysaccharide in inbred lines of chickens. PMID- 4152907 TI - Immunological diagnosis of human filariases: present possibilities, difficulties and limitations. PMID- 4152908 TI - Immunological study of carbon tetrachloride-mediated induction of tyrosine aminotransferase in rat liver. PMID- 4152909 TI - Importance of immediate gram-stain examination of the sputum in infections of the lower respiratory tract. PMID- 4152910 TI - Improved method for salicylazosulfapyridine analysis and partial characterization of impurities in commercial salicylazosulfapyridine. PMID- 4152911 TI - Improving medical service in long term care facilities. PMID- 4152912 TI - In intensive care units: flexibility--the key to critical care nursing. PMID- 4152913 TI - Increased incidence of urethane induced lung adenomata by autosensitized lymphocytes. AB - The present work investigates the influence of autosensitized lymphocytes on the carcinogenic response of the host. Urethane treated SWR mice received 6 fortnightly injections of lymphocytes sensitized in vitro against syngeneic fibroblasts. An increased incidence of lung adenomata was found in these mice compared with controls injected with unsensitized lymphoid cells or with lymphoid cells sensitized against unrelated transplantation antigens. Autosensitized lymphocytes also modified the response of host lymphoid cells to concanavalin A or to stimulation in a mixed lymphocyte culture assay. These results indicate that autoimmune lymphocytes may increase susceptibility of a host to the induction of tumours. PMID- 4152914 TI - Indirect pathogenicity of Gram-negative bacilli in the bronchi: the value of colistin aerosol. PMID- 4152916 TI - Induction of tyrosine aminotransferase and depression of protein synthesis in rat liver by a tryptophan-free mixture of amino acids. PMID- 4152915 TI - Induction of rat liver enzymes by polychlorinated biphenyls (PCBs) in dependence on the dose and chlorine content. PMID- 4152917 TI - Inflammatory bowel disease. PMID- 4152918 TI - Influence of acute pretreatment with delta 9-tetrahydrocannabinol on the LD50 of various substances that alter neurohumoral transmission. PMID- 4152919 TI - Influence of the alternate complement pathway in opsonization of several bacterial species. AB - In normal human serum chelated with magnesium (10 mM) and ethylene glycotetraacetic acid (10 mM) (MgEGTA), the classical pathway of complement activation is blocked; however, the alternate pathway of complement activation is intact. Diplococcus pneumoniae, Staphylococcus albus, Streptococcus viridans, Streptococcus faecalis, and Serratia marcescens were opsonized in normal human serum containing 10 mM MgEGTA. In contrast, Staphylococcus aureus and Pseudomonas aeruginosa were poorly opsonized in human serum chelated with 10 mM MgEDTA. Therefore certain bacterial species appear to require the classical pathway of complement activation to be opsonized and other bacterial species utilize the alternate pathway of complement activation. PMID- 4152920 TI - Inhibition of a minor pathway of L-dopa metabolism in the intestinal lumen using a decarboxylase inhibitor (Ro 4-4602). PMID- 4152921 TI - Inhibition of energization of Salmonella typhimurium membrane by zinc ions. PMID- 4152922 TI - Inhibition of motor transmission in the vas deferens of the rat by adrenergic neuron blocking agents and beta-adrenoceptor blocking agents having local anaesthetic effects. PMID- 4152923 TI - Inhibition of prolyl hydroxylase by collagen. PMID- 4152924 TI - Insulin, its chemistry and biochemistry. PMID- 4152925 TI - Interaction between the predator Toxorhynchites brevipalpis and its prey Aedes aegypti. AB - In a circumscribed area in Tanzania where the predacious larvae of Toxorhynchites brevipalpis were particularly abundant, it was found that water-filled tires and tins containing Toxorhynchites larvae had fewer larvae of Aedes aegypti than those without the predator larvae. The peaks of infestation with Toxorhynchites larvae occurred almost a month later than the peaks of A. aegypti infestation. Cannibalism was observed among the predator larvae in these containers. PMID- 4152926 TI - Interaction of luteinizing hormone and its subunits in corpus luteum supernatant. PMID- 4152927 TI - Interaction of primary amines with a mixed-function amine oxidase isolated from pig liver microsomes. PMID- 4152928 TI - Interactions of chlorpheniramine ethanol combinations: acute toxicity and antihistaminic activity. PMID- 4152929 TI - Interference by tryptophan analogues of an in vitro assay for liver tyrosine transaminase activity. PMID- 4152931 TI - Intracellularly injected aequorin detects transmembrane calcium flux during action potentials in an identified neuron from the terrestrial slug, Limax maximus. PMID- 4152930 TI - International seminar research on alcohol, drugs and driving. PMID- 4152932 TI - Investigations into the positive inotropic effect of clondine in isolated hearts. PMID- 4152933 TI - Involution of the thymus dependent lymphoid system. PMID- 4152934 TI - Isolation of an ATP-Pi exchangease from lysolecithin-treated electron transport particles. PMID- 4152935 TI - Joint cartilage and the homograft reaction. PMID- 4152936 TI - Kainic acid: a powerful neurotoxic analogue of glutamate. PMID- 4152937 TI - Leiomyosarcoma of the foot presenting as an arteriovenous fistula. PMID- 4152938 TI - Letter: Considerations in the drug treatment of drug-induced and other acute dyskinesias. PMID- 4152939 TI - Letter: Fatal aplastic anemia with piperacetazine therapy. PMID- 4152940 TI - Letter: Fatal insect stings. PMID- 4152941 TI - Letter: Lawn mower injuries. PMID- 4152942 TI - Letter: Tricyclic antidepressants and phenothiazines. PMID- 4152943 TI - Leukocytoclastic vasculitis. PMID- 4152944 TI - Liver enzymes and pathology in Hodgkin's disease. PMID- 4152945 TI - Lymphographic findings in granulomatous inflammations and connective tissue diseases. Differential diagnosis between these diseases and lymphomas. PMID- 4152947 TI - Malignant degeneration of cryptorchid testes following orchiopexy. PMID- 4152948 TI - Manipulation of sexual physiology by brain stimulation in insects. PMID- 4152946 TI - Lysosomal physiology in Tetrahymena. 3. Pharmacological studies on acid hydrolase release and the ingestion and egestion of dimethylbenzanthracene particles. AB - The ingestion of (14)C-labeled 9,10-dimethyl-1,2-benzanthracene particles, the extracellular release of acid phosphatase, ribonuclease, and alpha-glucosidase, and the egestion of preingested dimethylbenzanthracene particles by Tetrahymena taken from logarithmically growing cultures and resuspended in a dilute salt solution were followed in the presence of several pharmacologic agents. Serotonin, caffeine, and, to a lesser extent, dibutyryl cyclic AMP increased the rate of particle ingestion, but did not alter the rate of release of the three acid hydrolases studied. Added catecholamines did not affect either particle ingestion or acid hydrolase release, but particle ingestion was inhibited by the catecholamine antagonists, dichloroisoproterenol, desmethylimipramine, reserpine, and phenoxybenzamine. These drugs also increased the release of acid phosphatase and ribonuclease in 5-h incubations. Desmethylimipramine acted within 1 h to increase acid hydrolase release, but the effect of dichloroisoproterenol developed more slowly and was secondary to a change in cellular content of the hydrolases. Desmethylimipramine increased the energy of activation for the release of acid phosphatase, while dichloroisoproterenol did not. Both of these drugs enhanced the egestion of preingested dimethylbenzanthracene particles, supporting the view that acid hydrolase release occurs through a cytoproct egestion mechanism. Particle ingestion was also inhibited by colchicine, vinblastine, and cytochalasin B, but these agents had no effect on acid hydrolase release, thus further differentiating the properties of the ingestion mechanism from those of the egestion mechanism. It appears that both microtubules and microfilaments play a role in the ingestion process and that this process may be controlled in part by a cyclic AMP-mediated serotoninergic and adrenergic system. PMID- 4152949 TI - Meandering catheter. PMID- 4152950 TI - Measurement of outcome: a proposed scheme. PMID- 4152951 TI - Mechanism of stimulation of the hexose monophosphate shunt of erythrocytes by pyruvate. PMID- 4152953 TI - Mechanisms of substrate binding with glutamine synthetase. Equilibrium isotope exchanges with the ovine brain, pea seed, and Escherichia coli enzymes. PMID- 4152952 TI - Mechanisms and defects of the phagocytic systems of defense against infection. PMID- 4152954 TI - Medical management of angina pectoris. PMID- 4152955 TI - Metabolic and endocrine functions of rats conditioned to Noble-Collip drum trauma. PMID- 4152956 TI - Metabolic changes in "frozen-clamped" livers of rats caused by ingestion of polychlorinated biphenyls. PMID- 4152957 TI - Metabolic changes in hemorrhagic shock. PMID- 4152958 TI - Metabolic regulation in enzyme-deficient red cells. PMID- 4152959 TI - Metabolic, hormonal and enzymatic functions of rats during recovery from injury. PMID- 4152960 TI - Metabolism of cortisol by fetal rat liver explants. PMID- 4152961 TI - Metabolism of 3-(2-dimethylaminoethyl)benzo(b)thiophene in vitro and in vivo in the rat. PMID- 4152962 TI - Microbial production of pharmacologically active compounds other than antibiotics. PMID- 4152963 TI - Modified nitroprusside-colorimetric determination of antazoline salts in some pharmaceutical preparations. PMID- 4152964 TI - Morphine metabolism. I. Evidence for separate enzymes in the glucuronidation of morphine and p-nitrophenol by rat hepatic microsomes. PMID- 4152965 TI - Morphological and cytochemical studies of synapses formed in culture between isolated rat superior cervical ganglion neurons. PMID- 4152966 TI - MMPI and clinical scales compared. PMID- 4152967 TI - N-hydroxylation of 4,4'-diaminodiphenylsulphone in liver microsomes and in vivo. PMID- 4152968 TI - Nectar sources of Wisconsin mosquitoes. PMID- 4152969 TI - Neurovirulence of vaccinia viruses for mice. PMID- 4152970 TI - New host records of Stempellia magna, a microsporidan parasite of mosquitoes. PMID- 4152971 TI - New spasmolytically effective basic carbanilates. PMID- 4152972 TI - Nitrite reductase from A. fischeri: amino acid composition and hydrodynamic properties. PMID- 4152974 TI - Nomifensine: a new potent inhibitor of dopamine uptake into synaptosomes from rat brain corpus striatum. PMID- 4152973 TI - Nitrogen oxidation in ferrihaemoglobin formation. PMID- 4152975 TI - Normal and experimentally modified development of buds in Cassiopea (phylum Coelenterata; class Scyphozoa). PMID- 4152976 TI - NADP malate dehydrogenase, acetyl-CoA synthetase and ATP citrate lyase in the developing rat brain. PMID- 4152977 TI - Observations on the discharged granules from guinea-pig bone marrow basophils following anaphylaxis. PMID- 4152980 TI - On the first steps of lactate oxidation by bakers' yeast L-(plus)-lactate dehydrogenase (cytochrome b2). PMID- 4152978 TI - Occurrence of adenyl cyclase activity in human erythrocytes. PMID- 4152981 TI - On the influence of exogeneous cyclic AMP (3',5'-adenosine monophosphate) on amyloid formation in casein-treated C3H mice. PMID- 4152979 TI - On facilitation of transmitter release at the toad neuromuscular junction. AB - 1. The time dependence of the increase in amplitude (facilitation) of a second end-plate potential (e.p.p.) elicited within 10-100 msec of a preceding e.p.p. was examined at neuromuscular junctions in sartorius muscles of toads. Facilitation was defined by two characteristics, initial facilitation and the time constant of its exponential decay.2. The time constant of decay of facilitation was longer at lower temperatures and the Q(10) was 4.3 in the range 10-25 degrees C. There was no significant effect of temperature on initial facilitation.3. Ouabain (10(-4)-10(-3)M), lithium substitution for sodium, sodium azide (5 mM) and N-ethylmaleimide (NEM, 0.1 mM) initially had no effect on initial facilitation or the decay of facilitation. After some time, they all caused a longer time constant of decay of facilitation and a depression of initial facilitation.4. It was concluded that the decay of facilitation is not directly dependent on active transport of sodium ions, calcium efflux, ATP dependent movements of calcium or mitochondrial uptake of calcium following an action potential.5. Ouabain, lithium, sodium azide, and NEM all caused an increase in transmitter release. This effect, and the late effects on facilitation, were thought to be due to an increase in intracellular calcium concentration in nerve terminals.6. No relationship was found between the quantal content of e.p.p.s (range, 0.8-100) and initial facilitation, or the time constant of decay of facilitation.7. Substitution of strontium for calcium ions caused a marked prolongation of the time constant of decay of facilitation, and a depression of initial facilitation.8. The results were consistent with the hypothesis that the time constant of decay of facilitation is related to the rate of disappearance of an ;active' complex of calcium (CaA) which, of itself, is not sufficient for transmitter release. It is suggested that an action potential produces CaA which decays with the time constant of facilitation and CaS, a short life complex of calcium which decays with the time constant of the phasic release of transmitter. The release of transmitter is proportional to some function of [CaA] and [CaS]. PMID- 4152982 TI - On the mechanism of action of thyroxin, an amino acid analog of tyrosine. PMID- 4152983 TI - On the role of the adrenergic receptors for extraneuronal amine uptake and retention in rat salivary glands in vitro. PMID- 4152984 TI - Oral leukocytes and gingivitis in the primary dentition. PMID- 4152985 TI - Osmotic fragility of liposomes as affected by antihelmolytic compounds. PMID- 4152986 TI - Parental MMPIs and certain pathological behaviors in children. PMID- 4152987 TI - Partial separation and interconversion of NADH- and NADPH-linked activities of purified glyceraldehyde 3-phosphate dehydrogenase from spinach chloroplasts. PMID- 4152988 TI - Partially treated meningitis. PMID- 4152989 TI - Pentazocine analgesia and regional rat brain catecholamines. PMID- 4152990 TI - Permeability of films of ethyl cellulose and PEG to caffeine. PMID- 4152991 TI - Persistence of Diplococcus pneumoniae after influenza virus infection in Macaca mulatta. AB - Exposure of monkeys to aerosols of influenza virus followed later by aerosols of Diplococcus pneumoniae resulted in persistence of the bacteria in the upper respiratory tract for an average of 28 days. Examination of selected tissues for pneumococci revealed that pneumococci were widely disseminated throughout the respiratory tract at 3 and 7 days after exposure, but were cleared from lower respiratory tissues and were found mainly in tonsils, oropharynx, and posterior nasopharynx after 14 days. PMID- 4152992 TI - Personality characteristics of state hospital Patients' Rights Office visitors. PMID- 4152993 TI - Personality correlates of renal dialysis patients and their spouses. PMID- 4152994 TI - Pertussis vaccination. PMID- 4152995 TI - Pharmacokinetics and biotransformation of chlorpropamide in the rat and dog. PMID- 4152996 TI - Pharmacology of a new beta-adrenoceptor blocking agent, The 15219. PMID- 4152997 TI - Pharmacotherapy of schizophrenia. PMID- 4152998 TI - Philip Ellman lecture. Immunological aspects of systemic diseases of the lungs. PMID- 4152999 TI - Photoinhibition of isolated complexes I, II, and 3 of beef heart mitochondria. PMID- 4153000 TI - Photophosphorylation and the 518 NM absorbance change in tightly coupled chloroplasts. PMID- 4153001 TI - Physiological disposition of 2,6-dimethyl-4-benzyl-4-demethylrifampicin in rats, mice, and dogs. PMID- 4153002 TI - Piperacetazine vs. thioridazine for the control of schizophrenia in outpatients. PMID- 4153003 TI - Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by alpha- and beta-adrenoceptors. PMID- 4153004 TI - Possible role of adrenergic mechanisms in the systemic anti-inflammatory activity of acetic acid in rats. PMID- 4153005 TI - Potentiation of drug-initiated adrenal tyrosine hydroxylase induction by diazepam. PMID- 4153006 TI - Powder mixing in the tableting of fenfluramine hydrochloride: evaluation of a mixer. PMID- 4153007 TI - Practice management: The professional corporation--advantages and disadvantages. PMID- 4153008 TI - Prediction of drug oxidation rates in man: lack of correlation with serum gamma glutamyl transpeptidase and urinary excretion of D-glucaric acid and 6 beta hydroxycortisol. PMID- 4153009 TI - Primary care in the academic medical centers: A report of a survey by the AAMC. PMID- 4153010 TI - Problems interpreting the significance of multiple form patterns of rat liver tyrosine aminotransferase. PMID- 4153011 TI - Proceedings: Adrenergic receptors in heart muscle: similarity of apparent affinities of beta-blockers for receptors mediating adenyl-cyclase activity, inotropic and chronotropic effects of catecholamines. PMID- 4153012 TI - Proceedings: Antagonism by ICI 66082 of the effects of electrical stimulation on the right ansa subclavia of the dog. PMID- 4153013 TI - Proceedings: Chemical mediators and gonadotrophin secretion. PMID- 4153014 TI - Proceedings: Coexistence of monoamines in adrenergic synaptic vesicles. PMID- 4153015 TI - Proceedings: Compartmentalization of water in rat testis. PMID- 4153016 TI - Proceedings: Compartmentation of synaptic monoaminergic vesicles. PMID- 4153017 TI - Proceedings: Drug interaction on driving skills as evaluated by laboratory tests and by a driving simulator. PMID- 4153018 TI - Proceedings: Effect of synthetic luteinizing hormone-releasing hormone (LH-RH) in the human testicular function. PMID- 4153019 TI - Proceedings: Natriuresis, kaliuresis and urinary volume changes induced by cholinergic and adrenergic stimulation of the septal area of the rat brain. PMID- 4153020 TI - Proceedings: The effect of certain drugs on central synapses. PMID- 4153021 TI - Proceedings: The effect of various putative neurotransmitters on the release of CRH from the hypophysiotrophic hypothalamus in vitro. PMID- 4153022 TI - Production of an inflammatory exudate containing prostaglandins. PMID- 4153023 TI - Production of colony-stimulating factor in mixed leucocyte cultures. PMID- 4153024 TI - Properties of the assimilatory nitrate reductase from Aspergillus nidulans. PMID- 4153025 TI - Psychiatric problems of the aged. PMID- 4153026 TI - Purification and characterization of nicotinamide adenine dinucleotide-dependent methylenetetrahydrofolate dehydrogenase from Clostridium formicoaceticum. PMID- 4153027 TI - Purification and properties of pyridine nucleotide-independent L-lactate dehydrogenase from Polyporus circinatus. AB - Cell extracts of Polyporus circinatus grown on lactate catalyze the reduction of 2,6-dichlorophenolindophenol by l-lactate without the participation of nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotide phosphate. The enzyme has been purified 78-fold and was homogenous by disc gel electrophoresis. The optimal pH was found to be 6.7. The Michaelis constant for l lactate was 5.9 x 10(-4) M and the oxalate inhibition constant was 1.5 x 10(-4) M. The nature of the prosthetic group is discussed. PMID- 4153028 TI - Purification and properties of reconstitutively active and inactive adenosinetriphosphatase from Escherichia coli. AB - The Mg(2+)- and Ca(2+)-stimulated ATPase (EC 3.6.1.3; ATP phosphohydrolase) (bacterial coupling factor) was purified from two strains of E. coli by two different procedures: (a) method of Nelson, Kanner, and Gutnick [Proc. Nat. Acad. Sci. USA (1974) 71, 2720-2724] and (b) a modified procedure described in this paper. The ATPase purified from E. coli K12 (lambda) by the first procedure had 4 subunits (alpha, beta, gamma, and epsilon). It did not bind to a deficient membrane, nor did it reconstitute ATP-driven transhydrogenase activity. Our modified procedure (b) yielded 5 subunits (alpha, beta, gamma, delta, and epsilon). This ATPase could bind to a deficient membrane and reconstitute ATP driven transhydrogenase. This finding suggests that the delta subunit is required for the reaction with the membrane. The molecular weight of the 4-subunit ATPase was significantly lower than that of the 5-subunit ATPase, as judged by equilibrium centrifugation. The specific ATPase activities of both preparations were about the same. These two procedures were also applied to E. coli ML308-225. PMID- 4153029 TI - Purification and properties of NADP-dependent 17 beta-hydroxysteroid dehydrogenase solubilized from porcine-testicular microsomal fraction. PMID- 4153030 TI - Quantitative TLC of salicylazosulfapyridine. PMID- 4153031 TI - Quantum chemical studies of the metabolism of the inhalation anesthetics methoxyflurane, enflurane, and isoflurane. PMID- 4153032 TI - Radical production in amine oxidation by liver microsomes. PMID- 4153033 TI - Radiosensitivity of T and B lymphocytes. II. Effect of irradiation on response of T cells to alloantigens. PMID- 4153034 TI - Rapid eye movement (REM) sleep deprivation, stress and intermediary metabolism. PMID- 4153036 TI - Reaction mechanism of L-glutamate dehydrogenase. Transient complexes in the oxidative deamination of L-glutamate catalyzed by NAD(P)-dependent L-glutamate dehydrogenase. PMID- 4153035 TI - Rapid mixed lymphocyte culture test based on relative increase in protein synthesis. PMID- 4153037 TI - Recovery of medically important microorganisms from Apollo astronauts. PMID- 4153038 TI - Regulation of catecholamine synthesis in rat brain synaptosomes. PMID- 4153039 TI - Regulation of lipid synthesis in cultured animal cells. PMID- 4153040 TI - Regulation of protein synthesis by cyclic AMP. PMID- 4153041 TI - Relationship between locus of control, self-report and nonobtrusive measures of anxiety. PMID- 4153042 TI - Relationship of density of Culiseta melanura mosquitoes to infection of wild birds with eastern and western equine encephalitis viruses. PMID- 4153043 TI - Relationships between locus of control and MMPI scales among alcoholics: a replication and extension. PMID- 4153044 TI - Relative vasoconstrictor potencies of norepinephrine, alpha-methylnorepinephrine and octopamine. PMID- 4153045 TI - Relaxation therapies and neurosis: a central fatigue interpretation. PMID- 4153046 TI - Replicated actuarial correlates for three MMPI code types in juvenile delinquency. PMID- 4153047 TI - Resolved: that the present system of prenatal care is inadequate. A debate. PMID- 4153048 TI - Role of roots, hormones and light in the synthesis of nitrate reductase and nitrite reductase in rice seedlings. PMID- 4153049 TI - Role of the lysine-sensitive aspartokinase 3 in the regulation of DAP decarboxylase synthesis in Escherichia coli K 12. PMID- 4153050 TI - Scale equivalence and profile similarity of the Mini-Mult and MMPI in an outpatient clinic. PMID- 4153051 TI - Sea-anemone collagen: isolation and characterization of the cyanogen-bromide peptides. PMID- 4153052 TI - Search for phosphorylated forms of fatty acid synthesis enzymes in the living animal. PMID- 4153053 TI - Selected pharmacological studies of Luffa operculata. PMID- 4153054 TI - Self-evaluations of antidepressants. PMID- 4153055 TI - Seminiferous tubular immaturity and testicular neoplasia. PMID- 4153056 TI - Sensitivity tests on individual human cancers to pick active drug therapy. PMID- 4153057 TI - Serum-gamma-glutamyltranspeptidase (gamma-GT) and aspartate-aminotransferase (AspAT) activities in adult cattle with chronic Fasciola hepatica infection. PMID- 4153058 TI - Sex-dependent differences in drug metabolism in the rat. I. Temporal changes in microsomal drug-metabolizing system of the liver during sexual maturation. PMID- 4153059 TI - Sex-dependent differences in drug metabolism in the rat. II. Qualitative changes produced by castration and the administration of steroid hormones and phenobarbital. PMID- 4153060 TI - Sex-dependent differences in drug metabolism in the rat. IV. Effect of morphine administration. PMID- 4153061 TI - Sex-dependent differences in drug metabolism in the rat. 3. Temporal changes in type I binding and NADPH-cytochrome, P-450 reductase during sexual maturation. PMID- 4153062 TI - Significance of FEBS to world biochemistry. PMID- 4153063 TI - Simulated car driving influenced by cannabis and alcohol. PMID- 4153064 TI - Sinusitis and otitis in children. PMID- 4153066 TI - Smith-Lemli-Opitz syndrome in an adult. PMID- 4153065 TI - Skin reactions to systemic drug therapy. PMID- 4153067 TI - Social role performance and psychopathology among recently hospitalized and nonhospitalized mothers. II. Correlates with life stress and self-reported psychopathology. PMID- 4153069 TI - Some aspects of evolutionary pharmacology. PMID- 4153068 TI - Sodium cromoglycate (cromolyn sodium). II. Allergic rhinitis and other conditions. PMID- 4153070 TI - Some aspects of microsomal N- and C-oxygenation of aromatic amines. PMID- 4153072 TI - Special report: hospitals and inflation. PMID- 4153071 TI - Special article. The role of beta-adrenergic blockade in myocardial infarction. PMID- 4153073 TI - Specific inhibition of cytokynasis in E. coli by chemically unrelated compounds. PMID- 4153074 TI - Splanchnic blood flow in experimental shock. PMID- 4153075 TI - Stability of suspensions of rat liver microsomes quick-frozen with liquid nitrogen and stored at -85 degrees. PMID- 4153076 TI - Stenosis of the ureter caused by periarteritis. PMID- 4153077 TI - Steroid 17,20-lyase from testis microsomes: participation of NADPH cytochrome c reductase. PMID- 4153078 TI - Stoichiometry of drug metabolism in maturing male rats. PMID- 4153079 TI - Stress and hormonal intervention in the graft-versus-host response. PMID- 4153080 TI - Structural correlates of immune microenvironment. PMID- 4153082 TI - Studies on guanylate cyclase. A new assay method for guanylate cyclase and properties of the cyclase from rat brain. PMID- 4153081 TI - Studies on flavonoid metabolism. Excretion of m-hydroxyphenylhydracrylic acid from (plus)-catechin in the monkey (Macaca iris sp.). PMID- 4153083 TI - Studies on malaria and responses of Anopheles balabacensis balabacensis and Anopheles minimus to DDT residual spraying in Thailand. I. Pre-spraying observations. PMID- 4153084 TI - Studies on some metabolic effects of dopa and dopamine in the rat. PMID- 4153085 TI - Studies on the agglutinin specificities and blood group O(H)-like activities in extracts from the molluscs Pomacea paludosa and Pomacea urceus. PMID- 4153088 TI - Studies on the eyes of New Zealand parrot-fishes (Labridae). PMID- 4153087 TI - Studies on the effects of methylmercury on ethylmorphine N-demethylase and aniline hydroxylase activities and on the conversion of cytochrome P-450 to cytochrome P-420. PMID- 4153089 TI - Studies on the influence of T cells in antibody responses of mice to S3 and DNP lysine-S3. PMID- 4153086 TI - Studies on the biogenesis of smooth endoplasmic reticulum membranes in hepatocytes of phenobarbital-treated rats. II. The site of phospholipid synthesis in the initial phase of membrane proliferation. AB - The specific activity of the acyltransferases of smooth microsomes of rat liver rose threefold by 12 h after injection of phenobarbital, while the activity of the acyltransferases of the rough microsomes rose slightly to peak at 3-4 h, and subsequently fell. The latter rise was abolished by treatment of the animal with actinomycin D or puromycin, while that of the smooth microsomes was unaffected. Incorporation of [(14)C]glycerol into phospholipid of smooth microsomes was elevated 100% by phenobarbital, while that of the rough microsomes was elevated 15%, and this could be accounted for by exchange between the microsomal phospholipids. The phospholipid/protein ratio of the smooth microsomes rose 1.5 times 3-4 h after injection of phenobarbital, while that of the rough microsomes fell slightly. The specific activity of NADPH cytochrome c reductase and NADPH diaphorase rose first in the rough microsomes, and subsequently in the smooth microsomes at a time coinciding with the return of the phospholipid/protein ratio to the control level. The rise in phospholipid/protein ratio was unaffected by actinomycin D or puromycin. These results indicate that the proliferating smooth membranes are the site of phospholipid synthesis, and that the phospholipid/protein ratio of these membranes may change independently. PMID- 4153090 TI - Studies on the mechanism of inhibition of drug biotransformation by cyclic adenine nucleotides. PMID- 4153092 TI - Substrate inhibition of pigeon liver fatty acid synthetase and optimum assay conditions for over-all synthetase activity. PMID- 4153091 TI - Studies on the mechanism of the lung toxicity of paraquat: comparison of tissue distribution and some biochemical parameters in rats and rabbits. PMID- 4153093 TI - Sulfisoxazole as chemoprophylaxis for recurrent otitis media. A double-blind crossover study in pediatric practice. PMID- 4153095 TI - Suppression by alpha-methyltyrosine of ethanol-induced locomotor stimulation: partial reversal by L-dopa. PMID- 4153094 TI - Sulthiame: evaluation as an anticonvulsant. PMID- 4153096 TI - Surface characteristics of gelatin microcapsules by scanning electron microscopy. PMID- 4153097 TI - Survey on driver behaviour alcohol and drug. PMID- 4153098 TI - Synthetic 14-hydroxymorphinan narcotic antagonists. PMID- 4153100 TI - Taurine conjugation of fenclofenac in the dog. PMID- 4153099 TI - T-cell regulation of T-cell responses to antigen. PMID- 4153101 TI - Test-induced anxiety as a function of psychopathology. PMID- 4153102 TI - The activation of bovine pineal tryptophan 5-monooxygenase. PMID- 4153103 TI - The amino acid sequence of human myoglobin and its minor fractions. PMID- 4153104 TI - The antagonism between cholinomimetic agonists and beta-adrenoceptor stimulants. The differentiation between functional and metaffinoid antagonism. PMID- 4153105 TI - The binding of sulphonylureas to serum albumin. PMID- 4153107 TI - The choroidal tapetum lucidum of Latimeria chalumnae. PMID- 4153106 TI - The cellular basis of immunological recovery in nude mice after thymus grafting. PMID- 4153108 TI - The dangers of therapy without assessment: a case study. PMID- 4153109 TI - The distribution of Streptococcus mutans on the teeth of two groups of naval recruits. PMID- 4153110 TI - The effect of chlorcyclizine on cholesterol metabolism in mice. PMID- 4153111 TI - The effect of endocrinological manipulations on tyrosine hydroxylase and dopamine beta-hydroxylase activities in individual hypothalamic nuclei of the adult male rat. PMID- 4153112 TI - The effect of monoamine oxidase inhibitors on the rectal temperature of the rat. PMID- 4153113 TI - The effect of pyridine nucleotides on the activity of NADP-dependent isocitrate dehydrogenase from brain cytosol. PMID- 4153114 TI - The effects of 2H2O on mammary glucose-6-phosphate dehydrogenase. PMID- 4153115 TI - The fate of intravenous (3H)glycopyrrolate in man. PMID- 4153116 TI - The first ten years of FEBS: retrospect and prospect. PMID- 4153117 TI - The flagyl analogue of nicotinamide adenine dinucleotide. PMID- 4153118 TI - The foundation and early years of FEBS. PMID- 4153119 TI - The heroin problem: Some strategic aspects. PMID- 4153120 TI - The hospital's responsibility to visitors. PMID- 4153121 TI - The immunological properties of haptens coupled to thymus-independent carrier molecules. I. The characteristics of the immune response to dinitrophenyl-lysine substituted pneumococcal polysaccharide (SIII) and levan. PMID- 4153122 TI - The induction of a cellular immune reaction against self-antigens present in the thymus. PMID- 4153123 TI - The influence of a ganglion-blocking agent on experimental liver injury. PMID- 4153125 TI - The influence of environmental factors and physiological stage on flight patterns of mosquitoes taken in the vehicle aspirator and truck, suction, bait and New Jersey light traps. PMID- 4153124 TI - The influence of cytochrome P-450 induction on the metabolic formation of 455-NM complexes from amphetamines. PMID- 4153126 TI - The influence of methylene blue on the respiratory metabolism of the reticulocyte. PMID- 4153128 TI - The legal implications of the extended roles of professional nurses. PMID- 4153129 TI - The management of propoxyphene poisoning. PMID- 4153127 TI - The inhibition by beta-adrenoceptor blocking agents of calcium uptake into and efflux from isolated sarcoplasmic vesicles. PMID- 4153131 TI - The mosquitoes of the Santa Cruz faunal subarea of the Southwest Pacific (Diptera: Culicidae). PMID- 4153130 TI - The megathrombocyte as an index of platelet production. PMID- 4153132 TI - The non-nurse manager: new partner for professionals. PMID- 4153133 TI - The normality of the distribution in the sample when Viegas' simplified index for dental-caries experience is used. PMID- 4153135 TI - The pathologist's assistant. PMID- 4153134 TI - The oxidative cleavage of alkyl-nitrogen bonds in micro-organisms. PMID- 4153136 TI - The pathophysiology and treatment of migraine. PMID- 4153137 TI - The pharmacologic basis of antihypertensive therapy: The role of vasodilator drugs. PMID- 4153138 TI - The problem of postural hypotension. PMID- 4153140 TI - The repression-sensitization dimension and self-cognition in psychiatric inpatients. PMID- 4153139 TI - The proportion of lymphocytes capable of recognizing strong transplantation antigens in vivo. PMID- 4153141 TI - The role of autolysins in cell death. PMID- 4153142 TI - The role of malate in the cleavage of cholesterol side-chain in the course of progesterone biosynthesis in human term placenta. PMID- 4153143 TI - The role of malic enzyme in Aspergillus nidulans. PMID- 4153144 TI - The role of nitrogen oxidation in the excretion of drugs and foreign compounds. PMID- 4153145 TI - The role of NADH in uncoupled microsomal monoxygenations. PMID- 4153146 TI - The significance of amino acid inhibition of NADP-linked glutamate dehydrogenase in the physiological control of glutamate synthesis in Candida utilis. PMID- 4153148 TI - The structure of nitrones derived from amphetamines. PMID- 4153147 TI - The specificity of the rat-liver cholesterol 7alpha-hydroxylase. PMID- 4153149 TI - The synthesis of N6-(6-aminohexyl)-NAD+ and its application to affinity chromatography. PMID- 4153150 TI - The MMPI: a descriptive measure of psychopathology in abusive parents. PMID- 4153151 TI - The OR clinical co-ordinator: a supervisor plus. PMID- 4153152 TI - The 4-hydroxylation of cinnamic acid by sorghum microsomes and the requirement for cytochrome P-450. PMID- 4153153 TI - Tolerance in ovum fusion derived tetraparental mouse chimaeras. PMID- 4153154 TI - Traits of pain patients: the low-back "loser". PMID- 4153155 TI - Transplantation of haemopoietic stem cell (HSC) concentrates for treatment of immune deficiency disease. PMID- 4153156 TI - Treatment of asthma. Recent advances. PMID- 4153157 TI - Treatment of hypertension in the elderly. PMID- 4153158 TI - Ulcerative proctitis. PMID- 4153159 TI - Undergraduate marijuana and drug use as related to openness to experience. PMID- 4153160 TI - Utilization of a paramedic and a mobile ear clinic to provide otologic care in remote areas. PMID- 4153162 TI - Viruslike particles of Glossina fuscipes fuscipes Newst. 1910. PMID- 4153163 TI - When disaster strikes. PMID- 4153161 TI - Validity of the 133 xenon method for measuring coronary blood flow. Comparison with coronary sinus outflow determined by an electromagnetic flowprobe. PMID- 4153164 TI - Yersinia enterocolitica in small rodents. 1. Pilot study in two wildlife areas. PMID- 4153165 TI - Zinc-induced paracrystalline aggregation of glutamine synthetase. PMID- 4153166 TI - 2-(2,4-dichlorophenoxy) phenylacetic acid (fenclofenac): one of a novel series of anti-inflammatory compounds with low ulcerogenic potential. PMID- 4153167 TI - 6-Phosphogluconate dehydrogenase and enzymes of the Entner-Doudoroff pathway in Neisseria. PMID- 4153168 TI - [Disturbances of potency and libido in progressive muscular dystrophy (author's transl)]. PMID- 4153169 TI - [Activity of tyrosine aminotransferase in rat liver and thyroid gland after administration of glutamic acid in normal conditions and in hypoxia]. PMID- 4153170 TI - [Aging and enzymatic changes in rat parotid gland tissue (author's transl)]. PMID- 4153171 TI - [An unexplained syndrom with eye and tooth defects (author's transl)]. PMID- 4153173 TI - [Behavior of gamma-glutamyl transpeptidase in liver cirrhosis and liver stasis]. PMID- 4153172 TI - [Antiallergic action of sebrin (selenophen 6) in anaphylactic shock in guinea pigs]. PMID- 4153174 TI - [Behavioral psychotherapy]. PMID- 4153175 TI - [Beta blockaders in the treatment of patients with hypertensive disease under ambulatory conditions]. PMID- 4153177 TI - [Cerebral circulation during controlled hypotension]. PMID- 4153176 TI - [Bronchoconstrictor effects of forced inspiration in asthma]. PMID- 4153178 TI - [Change in the activity of a cell-free protein-synthesizing system with different functional states of the central nervous system]. PMID- 4153179 TI - [Chemically induced aplastic anemia]. PMID- 4153180 TI - [Clinical effect of salazosulfapyridine (salazopyrin) in Crohn's disease. A controlled double-blind investigation]. PMID- 4153182 TI - [Color reaction of 4-(3-dimethylaminopropylidene)-4,9-dihydrothieno(2,3 b)benzo(e)thiepine (Dithiaden) with concentrated sulfuric acid]. PMID- 4153181 TI - [Clinical experiences with a new beta-sympatholytic agent Ko 1366 (bunitrolol)]. PMID- 4153183 TI - [Comparative evaluation of the ganglionic blocking agents isoprine and pentamine under conditions of emergency medical care]. PMID- 4153184 TI - [Comparative study of clothiapine and trifluoperazine in acute episodes of paranoid schizophrenia]. PMID- 4153185 TI - [Condition of certain neurohumoral systems in patients with postpartum endomyometritis]. PMID- 4153186 TI - [Continuous sympathetic block in trench foot]. PMID- 4153187 TI - [Control of insomnia using a new benzodiazepine: flunidazepam or Ro 5-4200 (Phase I: Initial investigation. Phase II: Controlled study)]. PMID- 4153188 TI - [Demonstration of variations in enzyme activities at the level of the liver in grouped and isolated tadpoles of Alytes obstetricans Laur]. PMID- 4153189 TI - [Determination of the acute rejection phase in homotransplanted kidneys using the ultrasonic-Doppler method. (Animal expermental study)]. PMID- 4153190 TI - [Different nature of regional vasodilation during reflex inhibition of sympathetic vascular tonus]. PMID- 4153191 TI - [Differential diagnosis of arteritis]. PMID- 4153192 TI - [Directed measures of the ambulatory scope of improvement of stationary care from the viewpoint of a specialist for cardiovascular diseases]. PMID- 4153193 TI - [Double-blind clinical study of simple Noveril and of Noveril TR (Noveril 240 mg)]. PMID- 4153195 TI - [Editorial: A plan of action in the population question]. PMID- 4153194 TI - [Drinking water fluoridation in Karl-Marx-Stadt. XI. Gingiva and oral hygiene findings in resident children after 13 years of fluoridation of drinking water]. PMID- 4153196 TI - [Editorial: The reserves are dangerously low]. PMID- 4153197 TI - [Effect of anabolic steroids and adrenergic beta receptor blockaders on the indicators of rheogram of the aorta and lungs in patients with ischemic heart disease]. PMID- 4153198 TI - [Effect of ethanol on the central nervous system]. PMID- 4153199 TI - [Effect of halothane on the vasomotor tone of the dog's hindlimb (author's transl)]. PMID- 4153200 TI - [Effect of intravenous administration of gamma-hydroxybutyric and succinic acids on the metabolism of gamma-aminobutyric acid in the brain]. PMID- 4153201 TI - [Effect of typhoid endotoxin on the activity of enzymes of amino acid metabolism in the liver]. PMID- 4153202 TI - [Effect of unilateral cryptorchidism on testicular carbohydrate metabolism (author's transl)]. PMID- 4153203 TI - [Effect of working environment on the hard tissues of the teeth in workers of the aluminum mill at Skawina]. PMID- 4153204 TI - [Effects of ethanol on the metabolism of the liver]. PMID- 4153205 TI - [Effects of fluoromar on heart function and coronary circulation]. PMID- 4153206 TI - [Effects of hormones and chemical mediators on some functional parameters of the rabbit heart. II. Effect of vasopressin]. PMID- 4153207 TI - [Effects of some anesthetics on the cerebral electric activity]. PMID- 4153208 TI - [Encephalitis in childhood (actual problems)]. PMID- 4153209 TI - [Enhancing utero-placental blood flow with EPH-gestosis patients through long term therapy with beta-sympathomimetica (author's transl)]. PMID- 4153210 TI - [Etiology and pathogenesis of idiopathic Parkinsonism: a model]. PMID- 4153211 TI - [Glutamine synthetase activity in the liver in primary gout (author's transl)]. PMID- 4153212 TI - [Grave and unusual results of the use of some psychopharmacological agents]. PMID- 4153213 TI - [Histamine receptors and antagonists. New interesting views]. PMID- 4153214 TI - [Histidase-urocanase tests in the study of pathogenesis of certain dermatoses]. PMID- 4153216 TI - [Hypersensitive granulomatous giant cell angiitis as a rare variant of macroscopic nodular periarteritis]. PMID- 4153215 TI - [Histoenzymological characteristics of some processes in the lung accompanying bronchopulmonary cancer]. PMID- 4153217 TI - [Identification of a guanyl-cyclase in circulating human lymphocytes]. PMID- 4153218 TI - [Improvement of the methods of microbiological diagnosis of nonspecific infection in tuberculosis]. PMID- 4153219 TI - [Influence of anticonvulsive long-term therapy on the activity of various serum enzymes used in the diagnosis of hepatobiliary diseases]. PMID- 4153220 TI - [Influence of ethanol on the metabolism of drugs]. PMID- 4153221 TI - [Influence of the carbonated source on NAD+ and NADP+-ferredoxine oxidoreductase activities of Clostridium tyrobutyricum]. PMID- 4153222 TI - [Lymphocyte-macrophage interaction in the rejection reaction against isologous and homologous ascites tumors (author's transl)]. PMID- 4153223 TI - [Medical problems in compensation for vaccination injuries in children]. PMID- 4153224 TI - [Morphogenesis in Ascomycetes]. PMID- 4153225 TI - [Motion sickness and its treatment (author's transl)]. PMID- 4153227 TI - [New data on the physiopathology and therapy of bronchial constriction]. PMID- 4153226 TI - [Myocardial requirement for catecholamines during exertion]. PMID- 4153228 TI - [Nitrogen and carbohydrate-phosphate metabolism in the brain of warm-blooded animals during hypothermia and hibernation]. PMID- 4153229 TI - [NADP-reducing enzymes in rabbit adrenal glands in experimental hypercholesteremia]. PMID- 4153230 TI - [Orchidopexy using the Schoemaker technic]. PMID- 4153231 TI - [Plasma levels of testosterone and estradiol in prepuberal children with cryptorchism and anorchia before and after administration of HCG]. PMID- 4153232 TI - [Proceedings: Analysis of cholinergic components in guinea-pig vas deferens]. PMID- 4153234 TI - [Proceedings: 40th annual meeting of the German Society for Blood Circulation Research in Bad Nauheim from April 19 until April 21 1974]. PMID- 4153233 TI - [Proceedings: Effect of alufibrate (Atherolip) on pyruvate and lipoprotein metabolism in patients with hyperlipidemia type IV]. PMID- 4153235 TI - [Proliferative glomerulonephritis as a secondary disease]. PMID- 4153237 TI - [Pulmonary diseases due to drugs. II]. PMID- 4153236 TI - [Psychotic manifestations in children. I. Associated psychoses]. PMID- 4153238 TI - [Radiological determination of bone mineral content in vivo. Report on a working convention of the German Roentgen Society, 11, 24, 1974 in Erlangen]. PMID- 4153239 TI - [Septic complications following surgery in infancy]. PMID- 4153240 TI - [Significance of cholinoreactive substances in the brain in the formation and transport of hormones regulating coronary vessel tone]. PMID- 4153243 TI - [Stomatologic survey of the miner population]. PMID- 4153242 TI - [Stimulators of the beta-adrenergic receptors in the therapy of bronchial asthma]. PMID- 4153244 TI - [Study of the role of bacterial infection in chronic lung diseases in children]. PMID- 4153241 TI - [Some problems of practical geriatrics]. PMID- 4153245 TI - [Surgical help in septic complications]. PMID- 4153246 TI - [The masticatory function in 125 recently captured Macaca mulata monkeys]. PMID- 4153247 TI - [The pathogenic mechanisms and treatment of asthma]. PMID- 4153248 TI - [Therapy of ulcerative colitis]. PMID- 4153249 TI - [Transformation of enzymes]. PMID- 4153250 TI - [Transplantation of homogeneous joints, Attempt at immunosuppression by cyclophosphamide in a homogeneous osteocartilaginous graft]. PMID- 4153251 TI - [Treatment of chronic neuropsychiatric complications in alcoholism]. PMID- 4153252 TI - [Trial use of L-dopa associated with a dopa-decarboxylase inhibitor in Parkinson's syndrome]. PMID- 4153253 TI - [Various data on the epidemiology and clinical aspects of acute enterocolitis of staphylococcal origin]. PMID- 4153254 TI - [3d Siberian Congress of Health Departments (on the 100th anniversary of the birth of N. A. Semashko and the 50th anniversary of the 3d Siberian Congress of Health Departments)]. PMID- 4153255 TI - A controlled study of the effect of corticosteroids on immediate skin test reactivity. PMID- 4153256 TI - A dental health study of children attending dental hospitals in Rangoon and Birmingham. PMID- 4153257 TI - A hospital program toward physical fitness. PMID- 4153259 TI - A physician's assistant program for South Dakota. PMID- 4153258 TI - A new infantile acute febrile mucocutaneous lymph node syndrome (MLNS) prevailing in Japan. PMID- 4153260 TI - A psychological questionnaire predictive of myocardial infarction: results from the Kaiser-Permanente epidemiologic study of myocardial infarction. PMID- 4153261 TI - A quantitative lymph node weight assay for allogeneic interactions in the rat. PMID- 4153262 TI - A retrospective longitudinal study of caries prevalence during and 7 years after free dental care at school in Finland. PMID- 4153263 TI - A standard approach to therapy. PMID- 4153264 TI - A syndrome resembling pheochromocytoma following a stroke. Report of a case. PMID- 4153266 TI - Acute adverse reactions to psychoactive drugs, drug usage, and psychopathology. PMID- 4153265 TI - Activation of guanyl cyclase and intracellular cyclic GMP by fibroblast growth factor. PMID- 4153267 TI - Adrenergic mechanisms in canine hindlimb circulation. PMID- 4153268 TI - Adrenocorticotrophic hormone and the control of adrenal corticosteroidogenesis. PMID- 4153269 TI - Adrenodoxin reductase, the flavoprotein component of adrenal mitochondrial steroid hydroxylases. I. Purification and certain characteristics. PMID- 4153270 TI - Adrenodoxin reductase, the flavoprotein component of adrenal mitochondrial steroid hydroxylases. II. Functional aspects. PMID- 4153272 TI - Advanced prosthodontic education: projections by the American College of Prosthodontists, 1973 annual session. PMID- 4153271 TI - Adrenolytic and vasodilator therapy. PMID- 4153273 TI - Alteration of tyrosine aminotransferase multiple form patterns by antisickling agents and a decomposition product of antitumor agents. PMID- 4153274 TI - An evaluation of a hierarchical method of describing the pattern of dental caries attack. PMID- 4153275 TI - An instrumental method of quantitative estimation of the activity of oxidative enzymes. PMID- 4153276 TI - An oral health survey of Western Samoans. PMID- 4153277 TI - Anaerobic and aerobic energy metabolism in the larvae (tetrathyridia) of Mesocestoides corti. PMID- 4153278 TI - Analysis of the influence of selected neurotropic agents on hepatic metabolism in relation to endotoxicosis. PMID- 4153279 TI - Angiography in collagenous disease of the kidney. PMID- 4153280 TI - Anti-5HT activity of mephenesin (Myanesin) on the isolated guinea-pig ileum. PMID- 4153281 TI - Antihistaminic action of nicotinamide. PMID- 4153282 TI - Antitrachoma activity of streptovaricin. PMID- 4153283 TI - Association between fighting behavior and catecholamine biosynthetic enzyme activity in two inbred mouse sublines. AB - Levels of three adrenal catecholamine synthesizing enzymes and isolation-induced fighting behavior were studied in two related sublines of the Balb/c inbred mouse strain. Enzyme levels were twice as high in the adrenals of Balb/cJ mice as in those of the Balb/cN mice; heterozygous progeny were intermediate between their parents in the levels of the three enzymes. These sublines also showed marked differences in their fighting behavior after a 2-week isolation period. Balb/cJ mice fought immediately after presentation of an intruder mouse, while Balb/cN mice did not fight at any time during the test. Heterozygous progeny behaved more like the Balb/cN (non-fighters). Analysis of F(2) mice suggested that the differences in fighting behavior were determined by a single gene, with fighting being recessive. PMID- 4153284 TI - Biliary excretion and enterohepatic recirculation of methaqualone in the rat. PMID- 4153285 TI - Binding of adrenergic beta-receptor antagonists to human serum albumin. PMID- 4153286 TI - Binding of two adrenergic beta-receptor antagonists, alprenolol and H 93-26, to human serum proteins. PMID- 4153287 TI - Biochemistry of affective disorders. (A review of the literature). PMID- 4153288 TI - Biosynthesis and degradation of nicotinamide coenzymes in the myocardium. PMID- 4153289 TI - Canadian law vs. Catholic hospitals. PMID- 4153290 TI - Caries experience among children in Copenhagen. PMID- 4153291 TI - Caries-preventive effect of dentifrice containing 2percent sodium monofluorophosphate in a natural fluoride area in Denmark. PMID- 4153292 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 45-1974. PMID- 4153293 TI - Cell-bound receptors for alloantigens on normal lymphocytes. II. Antialloantibody serum contains specific factors reacting with relevant immunocompetent T lymphocytes. AB - The rat popliteal node graft-vs.-host assay was shown to depend on the presence of parental T cells in the inoculum. Antialloantisera raised in F(1) hybrid rats against alloantibodies of one parent directed at transplantation antigens of the other parent displayed some or all of the following specific effects on parental T cells: They inhibited local GvH by purified T-cell suspensions; they blocked the capacity of GvH-reactive cells to adsorb onto fibroblast monolayers of the relevant genotype; together with complement, they killed GvH-reactive cells. PMID- 4153294 TI - Cellular biochemical assessment of steroid activity. PMID- 4153295 TI - Changes in activity of enzymes metabolizing glucose 6-phosphate during development of the basidiomycete Schizophyllum. PMID- 4153296 TI - Characterization of minicells (nuclei) obtained by cytochalasin enucleation. PMID- 4153297 TI - Chemotherapy of delirium tremens: a survey of physicians' preferences. PMID- 4153298 TI - Colorimetric determination of antazoline in some pharmaceutical preparations with sodium nitrite. PMID- 4153299 TI - Commentary. Molecular pharmacology of beta-adrenergic receptors--a status report. PMID- 4153300 TI - Comparison of tasks and activities in physician-Medex practices. PMID- 4153301 TI - Conformational change with temperature and thermostability of glutamine synthetase from Bacillus stearothermophilus. PMID- 4153302 TI - Conformationally restricted analogs of histamine H1 receptor antagonists. 2 Phenyl- and 2-benzyl-1,2,3,4-tetrahydro-4-dimethylaminoisoquinoline. PMID- 4153303 TI - Content analysis of 27 anxiety inventories and rating scales. PMID- 4153304 TI - Contractlity in Spirostomum provides for nonelectrogenic calcium regulation through energy-dissipative metabolic processes in the absence of membrane excitability. PMID- 4153305 TI - Control by phytochrome of the level of nicotinamide nucleotides in the cotyledons of the mustard seedling. PMID- 4153306 TI - Control of the pacemaker system of the nerve-net in the sea anemone Calliactis parasitica. PMID- 4153307 TI - Conversion disorders: a review of research findings. PMID- 4153308 TI - Crystallization of E. coli aspartokinase I-homoserine dehydrogenase I. PMID- 4153309 TI - Current trends in the introduction of new drugs. PMID- 4153310 TI - Cyclic adenosine monophosphate and clinical medicine. 2. Carbohydrate and lipid metabolism. PMID- 4153311 TI - D-Galactose dehydrogenase from Pseudomonas fluorescens. Purification, properties and structure. PMID- 4153312 TI - Dental fluorosis and caries in high-fluoride districts in Sweden. PMID- 4153313 TI - Determination of serum morphine by the spin-label antibody technique. PMID- 4153314 TI - Dieldrin metabolism to cis-dihydroaldrindiol and epimerization of cis- to trans dihydroaldrindiol by rat liver microsomes. PMID- 4153315 TI - Differences in antigen handling by peritoneal macrophages from the Biozzi high and low responder lines of mice. PMID- 4153316 TI - Dihydroergotamine: a potent biological amplifer of sulphonylureas. PMID- 4153317 TI - Drug therapy of hypertension: what we have, what we need, what we expect. PMID- 4153318 TI - Drug therapy. Benzodiazepines (first of two parts). PMID- 4153320 TI - Editorial: Alcoholism and the mass media. PMID- 4153319 TI - Drugs, dry mouth, and dental disease. A case report. PMID- 4153321 TI - Editorial: Newborn identification procedures. PMID- 4153322 TI - Editorial: 1. Advanced emergency care delivery systems and the anesthetist. PMID- 4153323 TI - Edmund Andrews: the forgotten pioneer of Chicago urology. PMID- 4153324 TI - Effect of beta-adrenergic stimulation on myocardial adenine nucleotide metabolism. PMID- 4153325 TI - Effect of catecholamines on cardiac metabolism. PMID- 4153327 TI - Effect of ethanol on synthesis and active accumulation of gamma-aminobutyric acid in rat brain slices. PMID- 4153326 TI - Effect of divalent cations on ferredoxin-linked electron transport in chloroplasts. PMID- 4153328 TI - Effect of fluacizine on the uptake of exogenous noradrenalin by the isolated rat vas deferens. PMID- 4153329 TI - Effect of fluroxene anesthesia on the cornary circulation, myocardial oxygen consumption and cardiac contractility in dogs. PMID- 4153330 TI - Effect of histamine H2-receptor blockade on vagally induced gastric secretion in man. AB - Metiamide, an antagonist of histamine H(2) receptors, was administered intravenously to normal subjects and to patients with a peptic ulcer during vagal stimulation with a constant infusion of insulin. In normal and peptic-ulcer subjects there were reductions of 70% and 71% respectively in gastric-acid output compared with control tests on the same subjects. The decreased acid output resulted from a reduction in both volume of secretion and acid concentration. Metiamide is therefore a potent inhibitor of vagally-induced gastric acid secretion. PMID- 4153331 TI - Effect of isoproterenol on water diuresis. PMID- 4153333 TI - Effect of psychopharmacological agents on the gonads of female rats. PMID- 4153332 TI - Effect of pharmacologic conditioning on sulfadiazine toxicity and concentrations in plasma. PMID- 4153334 TI - Effect of sodium hydroxybutyrate on behavior of mice after prolonged isolation. PMID- 4153335 TI - Effect of some agents in the adenyl cyclase system on electrical activity of the toad urinary bladder. PMID- 4153336 TI - Effect of unilateral castration of the testis in artificial cryptorchidism. PMID- 4153337 TI - Effectiveness and toxicity of immunosuppressive agents: inhibition of the rat popliteal node graft-vs.-host reaction. PMID- 4153338 TI - Effects of a GABA--derivative (BA-34647) on spasticity. Preliminary report of a double-blind cross-over study. PMID- 4153339 TI - Effects of brief relaxation training on autonomic response to anxiety-evoking stimuli. PMID- 4153340 TI - Effects of suckling and food deprivation on the activity of citrate enzymes in the liver of the rat. PMID- 4153341 TI - Effects of the porphyrogenic agent 2-allyl-2-isopropylacetamide on the hydroxylation of testosterone in rat liver microsomal fraction. PMID- 4153342 TI - Effects of thyroid state on adrenoceptor properties. PMID- 4153343 TI - Effects of NADPH, NADP+, succinate and cyclic AMP on progesterone synthesis in subcellular fractions of rabbit ovarian interstitial tissue. PMID- 4153344 TI - Electron microscopic observation of the aboral organ of Ctenophora. I. The gravity receptor. PMID- 4153345 TI - Electron transport carriers involved in nitrogen fixation by the coliform, Klebsiella pneumoniae. PMID- 4153346 TI - Emergency treatment of petroleum distillate and turpentine ingestion. AB - A comparative study was made of pulmonary complications following the use of ipecac syrup and gastric lavage for hydrocarbon ingestion. The selected 255 patients had chest radiography when first seen and again two to five days later. Of these patients 74 or 29% had been treated with ipecac syrup, 41 or 16% by gastric lavage. On follow-up radiographs 19% of the ipecac-treated group were unchanged or worsened, compared with 39% of the lavage group, suggesting that pneumonitis was significantly less severe in the ipecac-treated patients. Use of ipecac is preferred over gastric lavage for alert patients who have ingested an excessive amount of hydrocarbon. PMID- 4153347 TI - Endocrine role of the lung in disease. PMID- 4153348 TI - Energization of energy-dependent transhydrogenase of Escherichia coli at a second site of energy conservation. PMID- 4153349 TI - Enzyme histochemistry of the human ovary. PMID- 4153350 TI - Epidemiological investigations of the respiratory tract bacteriology in patients with cystic fibrosis. PMID- 4153351 TI - Evaluation of physician's assistants in Gilchrist County, Florida. PMID- 4153352 TI - Exchange of neurotransmitter amino acid at nerve endings can simulate high affinity uptake. PMID- 4153353 TI - Exogenous energy sources for spermatozoa in cervical mucus of the cow at oestrus. PMID- 4153354 TI - Eye changes following phenothiazine administration. PMID- 4153355 TI - EKG of the month. PMID- 4153356 TI - Fat metabolism in higher plants. Properties of the palmityl acyl carrier protein: stearyl acyl carrier protein elongation system in maturing safflower seed extracts. PMID- 4153357 TI - Five-day perfusion of canine kidneys: a postulated effect of steroids. PMID- 4153358 TI - Fluorescence studies of nucleotides binding to diphtheria toxin and its fragment A. PMID- 4153359 TI - Foreign medical apparatus for obstetrics and gynecology. PMID- 4153360 TI - Further studies on the alteration of analgesic receptor-antagonist interaction induced by morphine. PMID- 4153361 TI - Giant axonal neuropathy. A clinically and morphologically distinct neurological disease. PMID- 4153362 TI - Glutamine amido transferase in yeast: changes in activity during the cell cycle. PMID- 4153364 TI - Goals of the World Medical Association. Protecting the freedom of doctors. Raising the standard of ethics. PMID- 4153363 TI - Glutathione turnover in the kidney; considerations relating to the gamma-glutamyl cycle and the transport of amino acids. AB - The overall turnover of glutathione in kidney and liver was determined in studies in which L-[(14)C]glutamate was administered to mice. Turnover was much more rapid (about 5 times greater) in kidney than in liver. Studies were also carried out in which 5-oxo-L-[(14)C]proline was administered; the first order rate constants for glutathione synthesis from 5-oxoproline in liver and kidney were not far from those found for synthesis of glutathione from glutamate in these tissues. The findings are in accord with the fact that the activities of the enzymes of the gamma-glutamyl cycle are much higher in kidney than in liver. The findings of high turnover of glutathione in kidney and the rapid utilization of 5 oxoproline by this organ for glutathione synthesis are consistent with the function of the gamma-glutamyl cycle in vivo and the proposed role of gamma glutamyl derivatives in amino-acid transport. PMID- 4153365 TI - Graft-versus-host and cytotoxic activity of rat thoracic duct lymphocytes fractionated by zonal centrifugation after culture on allogeneic fibroblasts. PMID- 4153366 TI - Graft-versus-host reaction in F 1 recipients in the absence of donor (parental) cell proliferation. PMID- 4153367 TI - Guidelines in the drug treatment of angina pectoris. PMID- 4153368 TI - G6PD kuanyama: a new variant of human erythrocyte glucose-6-phosphate dehydrogenase showing slower than normal electrophoretic mobility. PMID- 4153369 TI - Haemorrhagic and permeability increasing effects of 'Bothrops jararaca' and other Crotalidae venoms as related to amine or kinin release. PMID- 4153371 TI - Help for rural hospitals: the travelling rehab. team. PMID- 4153370 TI - Handling of bioactive materials by the lung (second of two parts). PMID- 4153372 TI - High-dose penicillin therapy and pneumococcal pneumonia. PMID- 4153373 TI - Histamine receptors in extra- and intracranial arteries. PMID- 4153375 TI - Hypertension as a community problem. PMID- 4153374 TI - Hydroxylations in biosynthesis and metabolism of bile acids. PMID- 4153376 TI - Ideational components of anxiety neurosis. PMID- 4153377 TI - Immunity, emotions and stress with special reference to the mechanisms of stress effects on the immune system. PMID- 4153378 TI - In vitro induction by phenobarbital of drug monooxygenase activity in mouse isolated small intestine. PMID- 4153379 TI - In whom we trust: a busy time for boards. PMID- 4153380 TI - Induction of glutamine synthetase in cultures of embryonic neural retina. Comments on the use of actinomycin D. PMID- 4153381 TI - Influence of parental lymphoid cells on the production of 19S and 7S antibodies in F1 hybrid mice. PMID- 4153382 TI - Inhibition of glucose 6-phosphate dehydrogenase by palmitoyl coenzyme A. PMID- 4153383 TI - Interpretations of DMF registrations of Norwegian recruits with emphasis on previous treatment experience. PMID- 4153384 TI - Intracellular distribution of 10-formyl tetrahydrofolic acid synthetase in spinach leaves. PMID- 4153385 TI - Irreversible binding of ethynylestradiol metabolites to protein: lack of methylation by S-adenosyl-methionine. PMID- 4153386 TI - Kinetics of prolytic events during red cell lysis induced by sea anemone nematocyst venom. PMID- 4153387 TI - Letter: Addictive drugs and alcoholism. PMID- 4153388 TI - Letter: Beta-adrenergic blocking agents in renal failure. PMID- 4153389 TI - Letter: Danger of saline emetics in first-aid for poisoning. PMID- 4153390 TI - Letter: Gamma-glutamyl transpeptidase in alcoholism. PMID- 4153391 TI - Letter: Infant morbidity conference. PMID- 4153392 TI - Letter: Interference from serum separators in gas-chromatographic drug analysis. PMID- 4153393 TI - Letter: Nomenclature and EC number of gamma-glutamyltransferase. PMID- 4153394 TI - Lincomycin and clindamycin colitis. PMID- 4153395 TI - Lipogenesis in aminonucleoside-induced nephrotic syndrome. PMID- 4153396 TI - Local effect of intranasal beclomethasone dipropionate aerosol in perennial rhinitis. PMID- 4153397 TI - Localization of intra-abdominal testes by selective testicular arteriography: a case report. PMID- 4153398 TI - Lymphocyte receptors for antigen. PMID- 4153399 TI - Malic enzyme inhibition by pregnenolone in bovine corpora lutea. PMID- 4153400 TI - Management of flexor spasms with Lioresal. PMID- 4153401 TI - Marine invertebrate origin of a reactant to mammalian T cells. PMID- 4153402 TI - Measurement of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities in erythrocytes by use of a centrifugal analyzer. PMID- 4153403 TI - Medical legacy of Apollo. PMID- 4153404 TI - Menarcheal age and personality: the choice of a statistical test of relationship. PMID- 4153405 TI - Metabolism and disposition of hydralazine-14C in man and dog. PMID- 4153406 TI - Metabolism of benz(a)anthracene epoxides by rat-liver. PMID- 4153407 TI - Modification of adrenergic block by noradrenaline low temperature and sodium deficiency. PMID- 4153408 TI - Modifications of ovarian and follicular contractility by amines. A mechanism involved in ovulation? PMID- 4153410 TI - Mosquito susceptibility levels to seven new insecticides and their comparative toxicity to the guppy, Poecilia reticulata, in Bangkok, Thailand. PMID- 4153409 TI - Morphine metabolism. II. Studies on morphine glucuronyltransferase activity in intestinal microsomes of rats. PMID- 4153411 TI - National statistics on caries and oral hygiene derived from the Danish Child Dental Health recording system. PMID- 4153412 TI - Necrotizing vasculitis and ulcerative colitis. PMID- 4153413 TI - New evidence for the role of the Sertoli cell and spermatogonia in feedback control of FSH secretion in male rats. PMID- 4153414 TI - New long latency bulbospinal evoked potentials blocked by serotonin antagonists. PMID- 4153415 TI - Nitrate and ammonium ion-selective electrodes as sensors. I. In bacterial growth curves for isolation of nitrate and nitrite reductases from Escherichia coli. PMID- 4153416 TI - Occurrence of Uranotaenia unguiculata Edwards, 1913 (Diptera, Culicidae) in Czechoslovakia. PMID- 4153417 TI - October is Immunization Action Month. PMID- 4153419 TI - On the differences in the sensitivity of coupling sites of submitochondrial particles to phospholipases A, C and and D. PMID- 4153418 TI - On the absence of cysteine in glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides. PMID- 4153421 TI - On the problem of diphenylhydantoin-induced seizures. An experimental approach. PMID- 4153420 TI - On the mechanism of photosynthetic oxygen reduction by isolated chloroplast lamellae. PMID- 4153422 TI - On the spectral intermediate at 440 nm formed during mixed function substrate oxidation. PMID- 4153423 TI - Opticianry, optometry, and ophthalmology: an overview. PMID- 4153424 TI - Optimized determination of gamma-glutamyltransferase by reaction-rate analysis. PMID- 4153425 TI - Oral health status and treatment needs in a disadvantaged, rural population in Norway. PMID- 4153426 TI - Oral manifestations of IgA deficiency. PMID- 4153427 TI - Organ weights and tyrosine aminotransferase levels in the rat during adaptation to periodic fasting. PMID- 4153428 TI - Organic hydroxylamine derivatives. X. Structural analogues of gamma-aminobutyric acid (GABA) of the isoxazole enol-betaine type. Synthesis of 5,6,7,8-tetrahydro 4H-isoxazolo (4,5-D) azepin-3-ol zwitterion and 4,5,6,7-tetrahydroisoxazole (4,5 c) pyridin-3-ol zwitterion. PMID- 4153430 TI - Personal history of Paget's disease. Osteitis deformans with several unusual features and their control. PMID- 4153429 TI - Parental awareness of the dental needs of 5-year-old children in the West Midlands, England. PMID- 4153431 TI - Personality characteristics of heroin addicts: a response to Gendreau and Gendreau. PMID- 4153432 TI - Phosphorylation of tyrosine aminotransferase in vivo. PMID- 4153433 TI - Phylogeny and correlations of aldehyde oxidase, xanthine oxidase, xanthine dehydrogenase and peroxidase in animal tissues. PMID- 4153434 TI - Physician assistants at Kaiser: distinctive patterns of practice. PMID- 4153435 TI - Platelet aggregation in asthmatic and normal subjects. PMID- 4153436 TI - Pleistophora milesi, a new species of microsporida from Maorigoeldia argyropus Walker (Diptera: Culicidae) in New Zealand. PMID- 4153437 TI - Potassium-induced release of the diuretic hormones of Rhodnius prolixus and Glossina austeni: Ca dependence, time course and localization of neurohaemal areas. PMID- 4153439 TI - Present treatment of manic states. PMID- 4153438 TI - Potentiation of amygdaloid kindling and metrazol-induced seizures by 6 hydroxydopamine in rats. PMID- 4153440 TI - Presidential address: The Endocrine Society. PMID- 4153442 TI - Primary ovarian pregnancy. PMID- 4153441 TI - Prevention by uncouplers of lipophilic chelator inhibition at three sites of mitochondrial electron transport. PMID- 4153443 TI - Probability of congenitally missing teeth: results in 1,191 children in the Burlington Growth centre in Toronto. PMID- 4153444 TI - Proceedings: Failure of burimamide and (15S)-15-methyl prostaglandin E2 to prevent histamine-induced gastric mucosal hyperaemia in the rat. PMID- 4153445 TI - Proceedings: The cardiovascular effects of dobutamine, a selective inotropic catecholamine. PMID- 4153446 TI - Proceedings: The inhibitory action of GABA and melatonin on the release of corticotrophin-releasing hormone from the rat hypophysiotrophic area in vitro. PMID- 4153447 TI - Prolonged survival of AKR mice following allogeneic bone marrow transplantation. PMID- 4153448 TI - Prospectus: the prevention of bacteremic pneumococcal pneumonia. A conservative appraisal of vaccine intervention. PMID- 4153449 TI - Pseudohermaphroditism, nephron disorder and wilms' tumor: a unifying concept. PMID- 4153450 TI - Psychic fatigability, its features and drug therapy. PMID- 4153451 TI - Psychologic implications of scrotal sac and testes for the male child. PMID- 4153452 TI - Psychological correlates of sleep habits reported by healthy young adults. PMID- 4153453 TI - Psychological measurements in Psychopharmacology. Introduction. PMID- 4153454 TI - Psychological study of patients with coronary heart disease with unexpectedly long survival and high level function. PMID- 4153455 TI - Pyridine nucleotides: basis for the hypotensive action of triphosphopyridine nucleotide. PMID- 4153456 TI - Pyridine-2,6-dicarboxylic acid (dipicolinic acid) formation in Bacillus subtilis. I. Non-enzymatic formation of dipicolinic acid from pyruvate and aspartic semialdehyde. PMID- 4153457 TI - Quality control of NADH. Evaluation of methods for detection of inhibitors and specifications for NADH quality. PMID- 4153458 TI - Quantitative electromyographic findings in some collagen diseases. PMID- 4153459 TI - Rapid induction of prolactin secretion by 3-iodo-L-tyrosine. PMID- 4153460 TI - Rational use of psychotropic drugs. II. Antianxiety agents. PMID- 4153461 TI - Reactions of a monospecific antiserum to ferredoxin-NADP+-reductase with chloroplast preparations. PMID- 4153462 TI - Recording system for the Danish Child Dental Health Services. PMID- 4153464 TI - Regulation of dinitrogen fixation in intact Azotobacter vinelandii. PMID- 4153465 TI - Regulation of the physician assistant in Massachusetts. PMID- 4153466 TI - Rehabilitation of the patient with chronic low back pain. PMID- 4153467 TI - Relation between social drug use-abuse and dental disease in California, U.S.A. PMID- 4153468 TI - Relative abilities of parental thymus and spleen cells to induce graft-versus host reactions and enhance antibody formation in F1 hybrid mice. PMID- 4153469 TI - Release of norepinephrine and dopamine-beta-hydroxylase by nerve stimulation. I. Role of neuronal and extraneuronal uptake and of alpha presynaptic receptors. PMID- 4153470 TI - Renin suppression. PMID- 4153471 TI - Root alkaloids of Rauwolfia oreogiton. PMID- 4153472 TI - Salicylate poisoning. PMID- 4153473 TI - Self-ideal-self discrepancy as a defensive style. PMID- 4153474 TI - Serotonin-induced muscle weakness. PMID- 4153476 TI - Sex-linked attenuation of the graft-versus-host reaction: effect on pathologic features, including tumor induction. PMID- 4153475 TI - Sex differences in the metabolism of xenobiotics by extrahepatic tissue in rats. PMID- 4153477 TI - Some newly observed correlations between structure and photochemical activity in chlorophyllin a and several derivatives. PMID- 4153478 TI - Some properties of Candida lipolytica yeast mitochondria. PMID- 4153479 TI - Splenic-gonadal fusion in a Japanese boy. PMID- 4153480 TI - Standardization of units in lung mechanics. PMID- 4153481 TI - Structural studies on the specific type VII pneumococcal polysaccharide. PMID- 4153482 TI - Studies of hyperimmune restricted and partially restricted anti-pneumococcal polysaccharide antibodies from allotype-defined pedigreed rabbits. I. Preparative liquid isoelectric focusing of the antibodies and characterization of the isolated fractions by electrophoretic techniques. PMID- 4153483 TI - Studies of hyperimmune restricted and partially restricted anti-pneumococcal polysaccharide antibodies from allotype-defined pedigreed rabbits. II. Allotypes and idiotypes in sera and electrofocused fractions. PMID- 4153484 TI - Studies on nitrite reductase from spinach leaves. I. Further purification and some properties. PMID- 4153485 TI - Studies on respiration and 11 beta-hydroxylation of deoxycorticosterone in mitochondria and intact cells isolated from the Snell adrenocortical carcinoma 494. PMID- 4153486 TI - Studies on the biotransformation of naphthalene-1,2-oxide in fetal and placental tissues of humans and monkeys. PMID- 4153487 TI - Studies on the induction and expression of T cell-mediated immunity. 3. Amplification by papain of the generation of cytotoxic lymphocytes to allogeneic cells. PMID- 4153488 TI - Study shows quick source for bacteria: foes among the flowers. PMID- 4153489 TI - Suicide attempts with drug overdose. Outcomes of intensive vs conventional floor care. PMID- 4153490 TI - Superinfections of the lung. An evaluation by serial transtracheal aspirations. AB - A prospective evaluation of cephaloridine, cephalothin, and lincomycin was conducted in 85 patients with pneumonia. None of the 50 with previous history of allergic sensitivity to penicillin had an allergic reaction. All cases of pure "pneumococcal pneumonia" were cured, regardless of the drug. Eight patients with polymicrobial pneumonia were cured by the cephalosporins, while lincomycin was ineffective in four patients who had polymicrobial pneumonia. Although expectorated sputum and exudates from the nasopharyngeal and oropharyngeal areas contained large concentrations of Staphylococcus aureus and various Gram-negative bacillary species during and at the end of therapy, serial cultures of transtracheal aspirate and the clinical course failed to confirm "superinfection" of the lung. PMID- 4153491 TI - Surgical Grand Rounds: Renal tumor. PMID- 4153492 TI - Sympathetic physiology and pharmacology. PMID- 4153493 TI - Synthesis and biological activity of DL-3-(5-benzimidazolyl)-2-methylalanine. PMID- 4153494 TI - Takayashu syndrome and pregnancy: a ten-year-follow-up. PMID- 4153495 TI - Takayasu's disease, revisited. PMID- 4153497 TI - The antagonism of the positive inotropic effect of histamine and noradrenaline by H1 and H2-receptor blocking agents. PMID- 4153496 TI - The acute biochemical response of the starved rabbit liver in situ to glucose infusion. PMID- 4153498 TI - The bleeding duodenal ulcer. PMID- 4153499 TI - The cardiovascular effects of histamine in laboratory animals. PMID- 4153501 TI - The development and introduction of new cardiovascular drugs. Seventh Bethesda Conference of the American College of Cardiology May 18-19, 1974, Washington D.C. Toxicology. PMID- 4153500 TI - The caries preventing effect of mouthrinsing with 0.025 percent sodium fluoride solution in Swedish children. PMID- 4153502 TI - The development and introduction of new cardiovascular drugs. Seventh Bethesda Conference of the American College of Cardiology May 18-19, 1974, Washington, D.C. I. Views of a cardiologist. PMID- 4153503 TI - The development and introduction of new cardiovascular drugs. Seventh Bethesda Conference of the American College of Cardiology May 18-19, 1974, Washington, D.C. II. Views of a Pharmaceutical manufacturer. PMID- 4153504 TI - The development and introduction of new cardiovascular drugs. Seventh Bethesda Conference of the American College of Cardiology May 18-19, 1974, Washington, D.C. 3. Views of the food and drug Administration. PMID- 4153505 TI - The effect of aerosol bronchodilators in the anaesthetized guinea-pig. PMID- 4153506 TI - The effect of phenobarbital pretreatment on the biotransformation of 3H digitoxigenin to 6beta-hydroxy-3-epidigitoxigenin by rabbit liver homogenates. PMID- 4153507 TI - The effects of beta adrenergic blockade on the responses of leucocyte counts to intravenous epinephrine in man. PMID- 4153508 TI - The effects of five preparatory methods upon child behavior during the first dental visit. PMID- 4153509 TI - The effects of substance P and other peptides on spinal neurons of the frog. PMID- 4153510 TI - The effects of N,N-2-dichloroethylaniline ("aniline mustard") on the murine immune system. PMID- 4153511 TI - The formation of complexes absorbing at 455 nm from cytochrome P-450 and metabloites of compounds related to SKF 525-A. PMID- 4153512 TI - The golden hamster as a definitive host of Taenia solium and Taenia saginata. PMID- 4153513 TI - The immunological properties of haptens coupled to thymus-independent carrier molecules. II. The influence of the graft-versus-host reaction on primary antibody responses to hapten-coupled polysaccharides and proteins. PMID- 4153514 TI - The in vitro hydrolysis of di-(2-ethylhexyl) phthalate by rat tissues. PMID- 4153515 TI - The isolated organ-cultured supraoptic nucleus as a neuropharmacological test system. PMID- 4153516 TI - The measurement of affects: depression and anxiety. PMID- 4153517 TI - The metabolism of acetophenone oxime in rat liver homogenates. PMID- 4153518 TI - The metabolism of polycyclic hydrocarbons by cultured human lymphocytes. PMID- 4153519 TI - The physician's assistant. PMID- 4153521 TI - The rat testis after vasectomy. PMID- 4153520 TI - The presence of histamine H2-receptors in rabbit kidney. PMID- 4153522 TI - The role of suppressor cells in avian allogeneic tolerance: implications for the pathogenesis of Marek's disease. PMID- 4153523 TI - The stimulation of partially purified bovine caudate tyrosine hydroxylase by phosphatidyl-L-serine. PMID- 4153524 TI - The susceptibility of the fetus and child to chemical pollutants. Immunologic responses to chemical pollutants. PMID- 4153525 TI - The training and utilization of feldshers in the USSR. A review prepared by the Ministry of Health of the USSR for the World Health Organization. PMID- 4153526 TI - The unknown poison. PMID- 4153527 TI - The use of allogeneic T lymphocytes and bacterial lipopolysaccharide to induce immune responses to monovalent haptens in vitro. PMID- 4153528 TI - The 2-hydroxylation of trans-cinnamic acid by chloroplasts from Melilotus alba Desr. PMID- 4153529 TI - Three methods of nursing audit. PMID- 4153530 TI - Tooth loss in a 19th century British population. PMID- 4153531 TI - Toxic sympathicopathy in uraemia. PMID- 4153532 TI - Utilization of oxygen and reduced nicotinamide adenine dinucleotide phosphate by human placental microsomes during aromatization of androstenedione. PMID- 4153533 TI - Validity and reliability of the Hooper Visual Organization Test. PMID- 4153534 TI - Variation in peroxisomal enzyme levels of peripheral leukocytes of cancer, leprosy, and tuberculosis patients. PMID- 4153535 TI - Verapamil in cardiology. PMID- 4153536 TI - World population year. PMID- 4153537 TI - 150th anniversary of Louis Pasteur's birth celebrated in U.S.S.R. PMID- 4153538 TI - 24Epsilon-methylcholestane-3beta,5alpha,6beta,25-tetrol 25-monoacetate. A novel polyhydroxylated steroid from an alcyonarian. PMID- 4153539 TI - 6-Hydroxydopamine induced degeneration of noradrenaline neurons in the scorbutic guinea-pig. PMID- 4153540 TI - [The activity of several enzymes in visual cortex neurons following early interruption of visual function]. PMID- 4153541 TI - [Can an endogenous depression be triggered by an accident?]. PMID- 4153542 TI - GABA as a transmitter in the central nervous system of vertebrates. PMID- 4153543 TI - [Two cases of so-called male Turner syndrome (author's transl)]. PMID- 4153544 TI - Main characteristics of an induced decrease in leg motor reactivity ("desensitization") in the cockroach. PMID- 4153545 TI - MMPI characteristics of mothers of pre-school children who are emotionally disturbed or have behavior problems. PMID- 4153546 TI - [The clinical pharmacology of a new specific adrenergic beta bronchodilator]. PMID- 4153547 TI - [Our directions for the treatment of cryptorchism]. PMID- 4153548 TI - [The effect of different treatment methods on the mortality of patients with hip fractures, analysis of data on 2072 injury cases]. PMID- 4153549 TI - [The fluoride content of teeth in endemic fluorosis]. PMID- 4153550 TI - Mass fragmentography of dopamine and 6-hydroxydopamine. Application to the determination of dopamine in human brain biopsies from the caudate nucleus. PMID- 4153551 TI - [The functional state of the kidneys during removal of brain tumors under nitrous oxide anesthesia with autonomic nerve block and arterial hypotension]. PMID- 4153552 TI - Weak graft-versus-host response of CBA lymphocytes against the H-2-identical strain C3H. PMID- 4153553 TI - [The heritage of Robert Jones and Agnes Hunt (report of a 6-month period of work at the Orthopedic Clinic of Oswestry)]. PMID- 4153555 TI - [Use of a new instrument in the osteotomy of the ascending mandibular ramus]. PMID- 4153554 TI - Some immunochemical properties and species specificity of GABA-alpha ketoglutarate transaminase from mouse brain. PMID- 4153556 TI - Role of a nurse on a psychiatric consultation service. PMID- 4153557 TI - Mode of antagonism between beta-adrenergic drugs and prostaglandin F2-alpha. PMID- 4153558 TI - [Use of obsidan in arterial hypertension]. PMID- 4153559 TI - [The patient who presents a risk]. PMID- 4153560 TI - Some properties of guinea pig brain glutamate decarboxylase and its inhibition by the convulsant allylglycine (2-amino-4-pentenoic acid). PMID- 4153561 TI - Some properties of kidney cortex and splenic microsomal NADPH-cytochrome c reductase. PMID- 4153562 TI - Some quantitative aspects of oxygen consumption and anaerobic metabolism of molluscan tissues--a review. PMID- 4153563 TI - Fast recording ion specific microelectrodes: their use in pharmacological studies in the CNS. PMID- 4153564 TI - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 47-1974. PMID- 4153565 TI - [The secretory-motor components of alimentary reactions in children in the presence of mental fatigue]. PMID- 4153566 TI - GABA selectively blocks parallel fiber-Purkinje cell synaptic transmission in the frog cerebellum in vitro. PMID- 4153567 TI - On a slow inhibitory effect of free fatty acids on the respiratory chain of non phosphorylating submitochondrial particles from beef heart. PMID- 4153569 TI - [The use of analeptic mixture following fluorothane anesthesia in the dental polyclinic]. PMID- 4153568 TI - Drug therapy. Benzodiazepines (second of two parts). PMID- 4153570 TI - [The value of renal arteriography in periarteritis nodosa (author's transl)]. PMID- 4153571 TI - Loss with age in NZB-W mice of thymic suppressor cells in the graft-vs-host reaction. PMID- 4153574 TI - Cell-mediated immunity and aging. PMID- 4153573 TI - Cell-mediated immunity after bacterial infection of the lower respiratory tract. AB - Lower respiratory tract and systemic cell-mediated immunity have been studied in rabbits after infection with Listeria monocytogenes or Diplococcus pneumoniae. Respiratory tract cell-mediated immunity was evaluated by direct and indirect assays of migration inhibitory factor (MIF) production. Systemic delayed hypersensitivity was determined by means of intradermal testing with appropriate antigens. Aerosol exposure to listeria was followed by markedly increased numbers of free lower respiratory tract cells. These cells manifested antigen-stimulated inhibition of migration (mean inhibition of migration = 30.4%). Pneumococcal pneumonia was associated with similar but less dramatic changes. Intravenous administration of organisms was uncommonly followed by inhibition of lower respiratory tract cells in direct migration assays. Fractionated MIF, as well as crude supernates of antigen-stimulated lower respiratory tract and lymph node lymphocytes from animals exposed to listeria aerosols, caused inhibition of normal alveolar macrophage migration. MIF, produced by lymph node lymphocytes, has a molecular weight of approximately 65,000 and is inactivated by chymotrypsin or neuraminidase. Delayed dermal hypersensitivity to listeria antigen was observed in 54 of 55 animals exposed to listeria aerosols and in all 9 animals infected by the intravenous route. Delayed dermal reactions to pneumococcal sonicate antigen (but not capsular polysaccharide) followed D. pneumoniae respiratory tract infection in 19 of 28 animals, and was elicited in 5 of 6 animals after intravenous infection. Both local (macrophage migration inhibition) and systemic delayed hypersensitivity followed bacterial infection of the lower respiratory tract. MIF activity was shown to be one mechanism for inhibition of alveolar macrophage migration. PMID- 4153575 TI - Anti-receptor antibody and resistance to graft-versus-host disease. PMID- 4153572 TI - Beta-adrenergic receptor blocking drugs in cardiac arrhythmias. PMID- 4153576 TI - [Is "dizziness" a disorder of consciousness in the sense of paragraph 3 part 4 of the General Accident insurance Conditions (AUB)?]. PMID- 4153577 TI - Gamma-aminobutyric acid and nervous system function--a perspective. PMID- 4153578 TI - Gamma-aminobutyric acid effects on pituitary gonadotropin secretion. AB - Gamma-aminobutyric acid (GABA) injected into the third ventricle of male rats promotes the release of pituitary luteinizing hormone (LH) but not follicle stimulating hormone. When GABA was injected directly into the pituitary it was ineffective in promoting LH release. This evidence suggests that GABA may play a role in controlling the discharge of hypothalamic luteinizing hormone releasing factor. PMID- 4153579 TI - Gamma-aminobutyric acid synthesised in the olfactory nerve. PMID- 4153581 TI - Infra-red TV for watching mosquito behaviour in the 'dark'. PMID- 4153580 TI - Gamma-aminobutyric acid: drug-induced elevation in monkey brain. PMID- 4153583 TI - Dental caries, gingivitis, and oral hygiene among schoolchildren in Kampala, Uganda. PMID- 4153582 TI - Characteristics of crayfish neuromuscular facilitation and their calcium dependence. AB - 1. A quantitative description of facilitation in the crayfish claw opener muscle is presented. The facilitation of a test response following one or more conditioning stimuli, and the growth of facilitation during a tetanus, are measured.2. In superficial central fibres facilitation following one or more impulses can be described as the sum of two components which are both maximum at the end of the conditioning train and decline simultaneously and exponentially with different time constants thereafter.3. During a tetanus, facilitation to successive stimuli grows more rapidly than is predicted by assuming that each impulse adds a constant facilitative effect to an accumulating total state of facilitation.4. Sufficiently large values of tetanic facilitation are predicted by a model which assumes that transmitter release is proportional to the nth power of a substance or factor accumulating in nerve terminals. But no single value of n predicts the correct rise of facilitation in a tetanus and the time course of its subsequent decline from the facilitation following a single spike.5. A model which assumes that the facilitative effects of successive spikes multiply in a tetanus predicts responses that are larger than those observed.6. The effects of varying the calcium concentration ([Ca(2+)]) on transmitter release and facilitation were studied. When a magnesium-EDTA buffering system is used to vary [Ca(2+)], transmitter release is found to be nearly linearly related to [Ca(2+)] in the range 0.1-13.5 mM.7. The magnitude and time course of facilitation during and following a tetanus are unaffected by varying [Ca(2+)] between 1.0 and 40 mM.8. The relation between ;steady-state' facilitation and stimulus frequency is also unaffected by changing [Ca(2+)], except that in high [Ca(2+)] transmitter release appears to saturate at high frequencies (above 30 Hz).9. The results are discussed in terms of the ;calcium accumulation' hypothesis of facilitation. The findings in crayfish appear to be qualitatively consistent with this hypothesis if certain modifications are made in the hypothesis. PMID- 4153584 TI - Social constriction in psychiatric patients: a normative study. PMID- 4153585 TI - A team approach to a disease survey on an aboriginal island (Orchid Island, Taiwan). IV. Mosquitos and chiggers on Lan-yu (Orchid Island), Taitung Hsien, Taiwan. PMID- 4153586 TI - Glutamate synthase from Escherichia coli--an iron-sulfur flavoprotein. Separation and analysis of non-identical subunits. PMID- 4153587 TI - Glutamate synthetase type activity in higher plants. PMID- 4153588 TI - Glutamine synthetase and ammonium regulation of nitrogenase synthesis in Klebsiella. PMID- 4153589 TI - Glutamine synthetase as a regulator of enzyme synthesis. PMID- 4153590 TI - Inflammation induced by histamine, serotonin, bradykinin and compound 48-80 in the rat: antagonists and mechanisms of action. PMID- 4153591 TI - [Advances in pulmonology. Drug-induced lung diseases]. PMID- 4153592 TI - Mechanism of ammonia assimilation in streptococci. PMID- 4153594 TI - Mechanized skin suturing. PMID- 4153593 TI - Mechanism of various drug effects on the Ca2+-dependent K+-efflux from human red blood cells. PMID- 4153595 TI - Agoraphobia. PMID- 4153596 TI - Clozapine and haloperidol in a single-blind cross-over trial: therapeutic and biochemical aspects in the treatment of schizophrenia. PMID- 4153597 TI - Clozapine in outpatient practice. PMID- 4153598 TI - Clozapine in the maintenance therapy of schizophrenia. PMID- 4153599 TI - [Clear cells and APUD series cells]. PMID- 4153600 TI - Appearance of gamma aminobutyrate transaminase activity in developing rat brain. PMID- 4153601 TI - Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes. PMID- 4153602 TI - Comparative aspects of glucose catabolism in Staphylococcus aureus and S. epidermidis. PMID- 4153603 TI - Comparative erythrocyte metabolism. PMID- 4153604 TI - Comparative hematology: studies on elephants, Elephas maximus. PMID- 4153605 TI - Comparative study of pyloric and fundic acid proteases in the guinea pig gastric mucosa: evidence for a pyloric pepsinogen. PMID- 4153606 TI - Richard Lende symposium. PMID- 4153608 TI - Periarteritis nodosa. PMID- 4153609 TI - Periarteritis nodosa--a compensable arterial condition? PMID- 4153607 TI - Comparison effects of metiamide and atropine on gastric and pancreatic secretion and peptic ulcer formation in cat. PMID- 4153610 TI - Primary affective disorder: Bender-Gestalt sequence of placement as an indicator of impulse control. PMID- 4153611 TI - Release of (3H)gamma-aminobutyric acid from glial cells in rat dorsal root ganglia. PMID- 4153612 TI - [A case of subdural hematoma, causing homolateral hemiparesis, diagnosed by carotid angiography]. PMID- 4153613 TI - The assessment of dental caries for public health purposes. PMID- 4153614 TI - Primate malarias. PMID- 4153616 TI - Isolation and partial characterization of a temperature-sensitive Escherichia coli mutant with altered glutaminyl-transfer ribonucleic acid synthetase. AB - A temperature-sensitive mutant of Escherichia coli has been found in which the conditional growth is a result of a thermosensitive glutaminyl-transfer ribonucleic acid synthetase. The corresponding genetic locus glnS is cotransduced with lip. In a strain containing the mutationally altered glutaminyl-transfer ribonucleic acid synthetase, no derepression of the enzyme itself nor of glutamine synthetase was observed. PMID- 4153615 TI - Isolation and characterization of melanocyte stimulating factors from the pituitary gland of the grey mullet, Mugil cephalus. PMID- 4153617 TI - [Relation between gamma-aminobutyric acid and tyrosine metabolism and changes in the brain and liver amino acid content in intact and adrenalectomized rats]. PMID- 4153618 TI - Isolation of cyclic AMP and cyclic GMP by thin-layer chromatography. Application to assay of adenylate cyclase, guanylate cyclase, and cyclic nucleotide phosphodiesterase. PMID- 4153619 TI - Oxidation of ethanol by hepatic microsomes of acatalasemic mice. PMID- 4153620 TI - Oxidation of fatty acids by mitochondria obtained from newborn subcutaneous (white) adipose tissue. PMID- 4153621 TI - Isolation of rat liver peroxisomes. PMID- 4153622 TI - Elevation of serum bilirubin and blood urea in pneumonia. PMID- 4153623 TI - [Negative inotropic effect of tricyclic antidepressants on the isolated right ventricular papillary muscle of the cat]. PMID- 4153624 TI - Oxidative metabolism of aflatoxin B1 by rat liver microsomes in vitro and its effect on lipid peroxidation. PMID- 4153625 TI - [Treatment of necrosis of the lunate bone by implantation of the pisiform bone]. PMID- 4153626 TI - [Treatment of status asthmaticus (author's transl)]. PMID- 4153627 TI - The attachment of IgG to cell components: a reconsideration of Brambell's receptor hypothesis of protein transmission. PMID- 4153628 TI - Is taurine an inhibitory neurotransmitter? PMID- 4153630 TI - Inhibition of graft-versus-host-reaction (GVHR) by in vitro incubation of donor lymphocytes with thymic or splenic chalone (s). PMID- 4153629 TI - Aerobic and anaerobic coproporphyrinogenase activities in extracts from Saccharomyces cerevisiae. PMID- 4153631 TI - Inhibition of synaptic vesicular Mg+2 dependent ATPase ('stenin') by antipsychotic phenothiazines. PMID- 4153632 TI - [Problems in the management of multiple fractures of the hip]. PMID- 4153634 TI - Metabolic scope, oxygen debt and the diurnal oxygen consumption cycle of the leopard frog, Rana pipiens. PMID- 4153633 TI - Antibody-dependent cell-mediated cytotoxicity. I. Differentiation from antibody independent cytotoxicity by "normal" IgG. PMID- 4153635 TI - Metabolism of drugs. LXXXI. Further studies on metabolism of prolintane in rabbits. PMID- 4153636 TI - Ionic composition of the plasma and whole blood of marine and fresh water eels, Anguilla rostrata. PMID- 4153637 TI - The cardiomyopathies. PMID- 4153638 TI - Source of oxygen in the conversion of 2-tridecanone to undecyl acetate by Pseudomonas cepacia and Nocardia sp. PMID- 4153639 TI - Source of reducing equivalents for the in vitro synthesis of chlorophyll from protochlorophyll. PMID- 4153640 TI - [Biochemistry, physiology and pharmacology of gamma-aminobutyric acid]. PMID- 4153641 TI - Branchial innervation and ciliary control in the ascidian Corella. PMID- 4153642 TI - [Psychopharmacological treatment of obsessive neurosis]. PMID- 4153643 TI - Gas chromatography and electron capture detection of benzophenone. IX. Identification of the chromic acid oxidation product of pipradrol. PMID- 4153644 TI - The chromosomes of giant trophoblast cells of the mouse. PMID- 4153645 TI - Principles of immunology and their application to newer diagnostic techniques in allergy. PMID- 4153646 TI - The clinical effect of salazosulphapyridine (Salazopyrin r) in Crohn's disease. A controlled double-blind study. PMID- 4153648 TI - Effect of anaphylaxis and histamine, pyrilamine and burimamide on levels of cyclic AMP and cyclic GMP in guinea-pig lung. PMID- 4153647 TI - Effect of anaesthetic agents on the synthesis and disappearance of brain dopamine normally and after haloperidol, Kcl or axotomy. PMID- 4153649 TI - Effect of burimamide on histamine- and pentagastrin-stimulated acid and pepsin secretion in the pig. PMID- 4153650 TI - Effect of chronic morphine implantation on tyrosine hydroxylase activity in the rat caudate. PMID- 4153651 TI - Effect of delta-9-tetrahydrocannabinol on free amino acids in brain. PMID- 4153652 TI - Effect of diet on activity of enzymes involved in fatty acid and cholesterol synthesis. PMID- 4153654 TI - Effect of metabolic inhibition on sodium ion exchange in the ventral nerve cord of Melanoplus differentialis. PMID- 4153653 TI - Effect of low calcium diet on bone and calcium metabolism in rats and mice--a differential species response. PMID- 4153655 TI - Effect of non-opiate antagonists on stereospecific opiate receptor binding of tritiated naloxone. PMID- 4153656 TI - Effect of washout of inducing steroid on gamma-glutamyl transferase activity in the cultured chick embryo retina. PMID- 4153657 TI - Selected maturational changes observed in the postnatal rat brain. PMID- 4153658 TI - Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture. AB - In the Reuber (H35) hepatoma cell strain, microsomal aryl hydrocarbon (benzo[a]pyrene) hydroxylase is induced 25-fold by the polycyclic hydrocarbon benz[a]anthracene but is not induced by the steroid hormone dexamethasone. Soluble tyrosine aminotransferase is induced sixfold by dexamethasone and twofold by benz[a]anthracene. Each enzyme requires similar inducer concentrations for induction, and their induction kinetics are similar. The induction of each enzyme requires RNA and protein synthesis; in each case the transcriptional and translational steps can occur independently. The two induction systems are differentially sensitive to inhibitors of macromolecular synthesis. Simultaneous exposure to both inducers produces increases in both enzyme activities that are greater than those produced by either inducer alone. Each inducer acts at a pretranslational level to produce this synergistic effect. The results suggest that the requirements for macromolecular synthesis are similar for the induction of each enzyme, but that the turnover of enzyme-specific macromolecules may differ for each. PMID- 4153659 TI - Induction of tyrosine transaminase activity by hydrocortisone in vitamin B-6 deficient rats. PMID- 4153660 TI - Infectious complications in patients with combined immunodeficiency diseases receiving bone marrow transplants. PMID- 4153661 TI - Selective solubilization of nicotinamide nucleotide transhydrogenase from the mitochondrial inner membrane. PMID- 4153662 TI - Effects of a simulated skylab mission on the oral health of astronauts. PMID- 4153663 TI - Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons. PMID- 4153664 TI - Effects of antimalarial drugs and clofibrate on in vitro lipid synthesis in Tetrahymena pyriformis GL. PMID- 4153665 TI - Effects of conjugated estrogens on plasma butaperazine levels. PMID- 4153666 TI - Effects of cupric ions on the radiolytic inactivation of lactate dehydrogenase. PMID- 4153667 TI - Effects of enflurane and fluroxene on lipid and carbohydrate metabolism in rats. PMID- 4153668 TI - Effects of estradiol and nicotinamide adenine dinucleotide phosphate on the rate of synthesis of uterine glucose 6-phosphate dehydrogenase. PMID- 4153669 TI - Effects of lipid peroxidation on the microsomal electron transport system and the rate of drug metabolism in rat liver. PMID- 4153670 TI - Effects of rapid and slow dehydration on the hemolymph osmolarity and Na+-K+ concentration in the millipede Pachydesmus crassicutis. PMID- 4153671 TI - Effects of spirometrid plerocercoids on several species of lower vertebrates. PMID- 4153672 TI - Effects of 6-hydroxydopamine on the nature of proteins undergoing axoplasmic transport in nigro-neostriatal neurons. PMID- 4153673 TI - Structure of mitochondrial cristae membranes. PMID- 4153674 TI - Lipid deposition and utilization in the sagebrush lizard, Sceloporus graciosus: its significance for reproduction and maintenance. PMID- 4153675 TI - Rapid diagnosis of bacterial meningitis. Demonstration of bacterial antigen by counterimmunoelectrophoresis. PMID- 4153676 TI - Blood groups and dental caries experience in man. PMID- 4153677 TI - Sound reception and processing in the carp: saccular potentials. PMID- 4153678 TI - Third special session of the Commission on Narcotic Drugs. PMID- 4153679 TI - A model for the mode of action of GABA on primary afferent terminals: depolarizing effects of GABA applied iontophoretically to neurones of mammalian dorsal root ganglia. PMID- 4153680 TI - [Epidemiology of bronchitis]. PMID- 4153681 TI - Immediate replantation and stabilization of avulsed teeth. PMID- 4153682 TI - [Studies on distribution and passage of tritium labelled fenoterol-hydrobromide (Th 1165a) in gravid and lactating rabbits]. PMID- 4153683 TI - [Studies on metabolism of bromazepam. IV. Hydroxylation of 2-(2-amino-5 bromobenzoyl)pyridine by liver microsomal enzymes (author's transl)]. PMID- 4153684 TI - [Studies on the strength of the soldered joint of different alloys (author's transl)]. PMID- 4153685 TI - Sex differences in the endorsement of MMPI critical items. PMID- 4153686 TI - [Tendovaginitis stenosans (de Quervain)]. PMID- 4153688 TI - Noradrenergic neurons: allosteric activation of hippocampal tyrosine hydroxylase by stimulation of the locus coeruleus. PMID- 4153687 TI - Noradrenaline-mediated inhibition by locus coeruleus of spinal trigeminal neurons. PMID- 4153689 TI - [Syndrome involving the extrapyramidal motor systems and their drug treatment]. PMID- 4153690 TI - [Study of repigmentation inexperimental leukoderma in guinea-pigs]. PMID- 4153691 TI - [Role of gamma-aminobutyric acid in metabolic processes in the brain and peripheral organs]. PMID- 4153692 TI - Trace peptides with positive inotropic action in blood plasma of dogs. I. Chemistry and physiological significance of the peptide constituents of an intermediate molecular weight (1000-10,000 daltons) peptide fraction from heparinized dog blood plasma. PMID- 4153693 TI - [Case report on mastocytosis in an adult]. PMID- 4153694 TI - [Time to abandon conservative education--the doctor should begin as an orderly?]. PMID- 4153695 TI - Nuclear magnetic resonance analysis of pharmaceuticals. 8. Carbromal and bromural in tablets. PMID- 4153696 TI - [Effect of a 2 percent solution of disodium cromoglycate in hay fever. Results of a double blind study with special attention to the serum IgE picture and to specific reagins to Timothy grass pollen]. PMID- 4153697 TI - [Effect of adrenoblockaders on the electrolyte composition of the myocardium]. PMID- 4153698 TI - [Effect of alkalosis on the neurohumoral control of heart rate]. PMID- 4153699 TI - [Effect of beta receptor blockaders on the atrioventricular stimulus conduction. Study by means of bundle of His electrocardiography]. PMID- 4153700 TI - [Effect of central cholinolytics on brain noradrenaline content before and after stimulation of intero- and exteroceptors]. PMID- 4153701 TI - [Effect of different pharmacological substances on arrhythmia caused by poisoning with cardiac glycosides]. PMID- 4153702 TI - [Effects of a heterologous immune serum against bone marrow cells of the mouse]. PMID- 4153703 TI - Tanned silks. PMID- 4153704 TI - Proceedings: Drug-induced stereotyped behavior: similarities and differences. PMID- 4153705 TI - Proceedings: Effect of chronic treatment with central stimulants on brain monoamines and some behavioural and physiological functions in rats, guinea pigs, and rabbits. PMID- 4153706 TI - Proceedings: Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons. PMID- 4153707 TI - Proceedings: Effects of the pharyngo-cibarial armature of mosquitoes on microfilariae. PMID- 4153708 TI - Proceedings: Multiparametric tests in the study of gastrointestinal neoplasms. PMID- 4153709 TI - Proceedings: Short- and long-term regulation of tyrosine hydroxylase. PMID- 4153710 TI - Proceedings: Short-term control of tyrosine hydroxylase. PMID- 4153711 TI - Proceedings: The effects of beta-adrenergic blockade upon the cardiovascular responses of the rat to noradrenaline infusions. PMID- 4153712 TI - [Brief report on the discussion of Working Group 5, DPG (German Psychoanalytical Society)--Working Session Berlin, Oct. 26-8, 1973]. PMID- 4153713 TI - The effect of adrenergic blockade on the glucagon responses to starvation and hypoglycemia in man. AB - In an attempt to ascertain whether the sympathetic nervous system modulates glucagon release in man during starvation and hypoglycemia, the influence of alpha and beta adrenergic blockade on glucagon responses was studied in young, healthy men subjected to fasting and insulin-induced hypoglycemia. Six volunteers fasted for 84 h on three separate occasions. Plasma immunoreactive glucagon (IRG), measured initially at 12 h, climbed gradually from mean levels of 54 pg/ml to a zenith of 124 pg/ml at 48 h, with maintenance of these levels for the duration of the fast. The infusion of propranolol or phentolamine throughout the terminal 24 h of the second and third fasts failed to alter the pattern of IRG release. After an overnight fast, five volunteers received insulin intravenously, which evoked a mean rise in plasma IRG levels from 63 pg/ml to a maximum of 256 pg/ml at 30 min. The concurrent administration of propranolol or phentolamine did not modify the glucagon responses to insulin-induced hypoglycemia. These data suggest that the augmented glucagon release in man during starvation or after hypoglycemia is not significantly regulated by signals from the adrenergic nervous system. PMID- 4153715 TI - The effect of extra bound cytochrome b-5 on cytochrome P-450-dependent enzyme activities in liver microsomes. PMID- 4153714 TI - The effect of external salinity upon lipid synthesis in the blue crab Callinectes sapidus Rathbun and in the spider crab Libinia emarginata Leech. PMID- 4153716 TI - The effect of immobilization and exercise on acetylcholine-mediated myopathies. PMID- 4153717 TI - The effect of salinity and temperature on the ion levels in the hemolymph of the blue crab, Callinectes sapidus, Rathbun. PMID- 4153718 TI - The effect of some beta-adrenergic blockers on human intraocular pressure. PMID- 4153719 TI - The effect of sorbitol-containing chewing gum on the incidence of dental caries; plaque and gingivits in Danish schoolchildren. PMID- 4153720 TI - The effectiveness of an adhesive sealant in preventing occlusal caries: findings after two years in Kalispell, Montana. PMID- 4153721 TI - The effects of a new adrenergic blocking agent (K4423) on exercise tolerance in angina pectoris. PMID- 4153722 TI - The effects of bovine prolactin, sea water and environmental calcium on water influx in isolated gills of the euryhaline teleosts, Anguilla japonica and Salmo gairdnerii. PMID- 4153723 TI - The effects of hypnosis, relaxation and reinforcement on hypnotic behaviors and experiences. PMID- 4153724 TI - Subcellular myocardial effects of verapamil and D600: comparison with propranolol. PMID- 4153725 TI - Epidemiology of Boraceia virus in a forested area in Sao Paulo, Brazil. PMID- 4153726 TI - Oxygen consumption of the beetle, Dermestes maculatus. PMID- 4153727 TI - Oxygenational properties of haemerythrin in the blood of Magelona papillicornis Muller (Polychaeta: Magelonidae). PMID- 4153728 TI - Evidence for a proton-dependent regulation of mitochondrial nicotinamide nucleotide transhydrogenase. PMID- 4153729 TI - Evidence for a relationship between ATP hydrolysis and changes in extracellular space and fibre diameter during rigor development in skeletal muscle. PMID- 4153730 TI - Evidence for cooperative Mn-ATP binding with Bacillus sp. glutamine synthetase. PMID- 4153731 TI - Evidence for the compartmentation of glutamate metabolism in isolated rat retina. PMID- 4153732 TI - Evidence for the functional interaction of two central neurotransmitters. PMID- 4153733 TI - Evidence for two different forms of guanylate cyclase in rat heart. PMID- 4153734 TI - Net energetic and thermoregulatory efficiency during panting in the sheep. PMID- 4153735 TI - [Adrenergic beta-receptor blocking activity of (3-amino-2-hydroxy)propoxy-3, 4 dihydrocarbostyril derivatives in anesthetized dog (author's transl)]. PMID- 4153736 TI - Congenital microgastria. A follow-up observation over six years. PMID- 4153737 TI - Current concepts of allergy of the eye. PMID- 4153739 TI - [Retention of two central biogenic amines during pharmacologic trials of a synthetic cardiovascular agent, carbamoyl-oxy-4 (fluoro-4-phenyl) (-4-oxo-4 butyl)-decahydroquinolinechlorhydrate, or L7810]. PMID- 4153738 TI - [Essential hypertension: Renin and aldosterone, key to pathogeny and therapy?]. PMID- 4153740 TI - Concentration and analysis of organic volatiles in Skylab 4. PMID- 4153741 TI - Letter: 'West syndrome'. PMID- 4153742 TI - Letter: tRNA and ageing. PMID- 4153743 TI - Letter: Clorazepate dipotassium in tardive dyskinesia. PMID- 4153744 TI - Letter: E.C.T. and cardiac arrhythmia. PMID- 4153745 TI - Letter: Post-herpetic pruritus. PMID- 4153746 TI - Letter: Preliminary trial with a continuous helium-cadmium laser as excitation source for the microspectrofluorometric assay of NAD(P)H in single living cells. PMID- 4153747 TI - Letter: Presweetened cereals. PMID- 4153748 TI - Conferences view auto deaths: the 'neglected disease'. PMID- 4153749 TI - Differential responses of two carboxylases from Euglena to the state of chloroplast development. PMID- 4153750 TI - Bacterial otitis media in the guinea pig. PMID- 4153751 TI - [Experience in the use of droperidol and the steroid narcotic Viadril G in parturients with late toxicosis]. PMID- 4153752 TI - Bacteriocin of phage type 71 S. aureus. PMID- 4153753 TI - [Internal Working Session of the DPG (German Psychoanalytical Society) Oct. 26-8, 1973 on continuing psychoanalytical education. Report on the discussion of Working Group 2]. PMID- 4153754 TI - [Internal Working Session of the DPG (German Psychoanalytical Society) Oct. 26-8, 1973 on continuing psychoanalytical education. Report on the discussion of Working Group 4]. PMID- 4153755 TI - [Internal Working Session of the DPG (German Psychoanalytical Society) Oct. 26-8, 1973 on continuing psychoanalytical education. Report on the discussion of Working Group 7]. PMID- 4153756 TI - Patterns, range and effects of misused psychotropic substances in Europe. PMID- 4153757 TI - [Cases of traumatic intrusion (author's transl)]. PMID- 4153758 TI - [Assessment of bronchial infection grading in chronic obstructive lung based on results of examinations of bronchial aspirates and transtracheal aspirates by the Pecora method]. PMID- 4153759 TI - [Intestinal fistulas in children]. PMID- 4153760 TI - Anxiety relief conditioning. A critical review and supportive experiment. PMID- 4153761 TI - Review of behavioral treatment of depression. PMID- 4153762 TI - Our experience with clozapine treatment. PMID- 4153763 TI - The eye and its disorders. 24. The treatment of external diseases. PMID- 4153764 TI - Brief report of MMPI characteristics of sexual deviation. PMID- 4153765 TI - Purification and kinetic properties of acyl and alkyl dihydroxyacetone phosphate oxidoreductase. PMID- 4153766 TI - Crayfish neuromuscular facilitation activated by constant presynaptic action potentials and depolarizing pulses. AB - 1. Experiments were conducted to test the hypothesis that facilitation of transmitter release in response to repetitive stimulation of the exciter motor axon to the crayfish claw opener muscle is due to an increase in the amplitude or duration of the action potential in presynaptic terminals. No consistent changes were found in the nerve terminal potential (n.t.p.) recorded extracellularly at synaptic sites on the surface of muscle fibres.2. Apparent changes in n.t.p. are attributed to three causes.(i) Some recordings are shown to be contaminated by non-specific muscle responses which grow during facilitation.(ii) Some averaged n.t.p.s exhibit opposite changes in amplitude and duration which suggest a change in the synchrony of presynaptic nerve impulses at different frequencies.(iii) Some changes in n.t.p. are blocked by gamma-methyl glutamate, an antagonist of the post-synaptic receptor, which suggests that these changes are caused by small muscle movements.3. The only change in n.t.p. believed to represent an actual change in the intracellular signal is a reduction in n.t.p. amplitude to the second of two stimuli separated by a brief interval.4. Tetra-ethyl ammonium ions increase synaptic transmission about 20% and prolong the n.t.p. about 15%. This result suggests that an increase in n.t.p. large enough to increase transmission by the several hundred per cent occurring during facilitation would be detected.5. The nerve terminals are electrically excitable, and most synaptic sites have a diphasic or triphasic n.t.p., which suggests that the motor neurone terminals are actively invaded by nerve impulses.6. When nerve impulses are blocked in tetrodotoxin, depolarization of nerve terminals increases the frequency of miniature excitatory junctional potentials (e.j.p.s), and a phasic e.j.p. can be evoked by large, brief depolarizing pulses. Responses to repetitive or paired depolarizations of constant amplitude and duration exhibit a facilitation similar to that of e.j.p.s evoked by nerve impulses.7. It is concluded that facilitation in the crayfish claw opener is not due to a change in the presynaptic action potential, but is due to some change at a later step in the depolarization-secretion process. PMID- 4153767 TI - The gallbladder of the guinea pig: its concentrating and contractile abilities. PMID- 4153768 TI - Changes in enzyme patterns produced by high potassium concentration and dibutyryl cyclic AMP in organ cultures of sympathetic ganglia. PMID- 4153769 TI - Changes in the MMPI as a function of thalamotomy. PMID- 4153770 TI - Changes of kinetic constant of striatal tyrosine hydroxylase elicited by neuroleptics that impair the function of dopamine receptors. PMID- 4153772 TI - (3H)glutamate uptake at insect neuromuscular junctions: effect of chlorpromazine. PMID- 4153771 TI - I-region genes are expressed on T and B lymphocytes. Studies of the mixed lymphocyte reaction (MLR). AB - Unidirectional mixed lymphocyte reactions (MLR) were performed between mouse strains differing for various segments within the H-2 complex. Thymocytes and purified lymph node T cells and B cells were used as stimulator cells. In three of five combinations studied, differing only within the I region, both T and B cells stimulated in the MLR. This suggests that the region codes for both T- and B-cell surface structures. However, if the difference was restricted to one I subregion (I-C), only T cells stimulated. This finding suggests that some of the I-region genes may be expressed either in T or in B cells. PMID- 4153773 TI - [Diagnosis and prognosis of silicosis]. PMID- 4153774 TI - Antagonists of the putative inhibitory transmitter effects of taurine and GABA in the retina. PMID- 4153775 TI - Inaugural address: 49th all-India medical conference. PMID- 4153776 TI - [Mechanism of the development of cervical syndromes; surgical considerations and results]. PMID- 4153777 TI - Saccharopine dehydrogenase. A kinetic study of coenzyme binding. PMID- 4153778 TI - On the induction of tyrosine aminotransferase in rat liver by alpha-methyl-p tyrosine. PMID- 4153779 TI - On the mechanism of glucose-6-phosphate dehydrogenase regulation in mouse liver. 1. Characterization of the system. PMID- 4153780 TI - On the nature of the interhemispheric effects of fatigue. PMID- 4153781 TI - Biochemical changes of myocardial necrosis induced by isoproterenol and protective effects of beta-blocker and anti-inflammatory drugs. PMID- 4153783 TI - Biochemical plasticity of short-axon interneurons: increased glutamate decarboxylase activity in the denervated area of rat dentate gyrus following entorhinal lesion. PMID- 4153782 TI - Biochemical effects of 3,5-diethoxycarbonyl-1,4-dihydrocollidine in mouse liver. PMID- 4153784 TI - [Methemoglobin and methemoglobin reductases in cattle]. PMID- 4153785 TI - Posthepatitis syndromes. PMID- 4153786 TI - Further clinical and EEG experience with clozapine. PMID- 4153787 TI - Further results of catches of Culicoides (Diptera: Ceratopogonidae) and mosquitoes from suction traps. PMID- 4153788 TI - Synthesis of dl-3-(hydroxymethyl)tyrosine. PMID- 4153789 TI - Teaching family medicine: progress report. PMID- 4153790 TI - [Methods of anesthesia in obstetric surgery]. PMID- 4153792 TI - Teichoic acid phosphorylcholine esterase. A novel enzyme activity in pneumococcus. PMID- 4153791 TI - [Pathogenetic significance of microbial neuraminidases]. PMID- 4153793 TI - Psychological aspects of pain and the selection of patients. PMID- 4153794 TI - The hyperactive child: who is he? PMID- 4153795 TI - [Variants in the clinical course of periarteritis nodosa in children]. PMID- 4153796 TI - Aortic calcification, serum calcium, magnesium, sodium and cholesterol in Gopherus polyphemus. PMID- 4153797 TI - Chemical and immunological characterisation of the major glucosamine-containing ganglioside of human tissues. PMID- 4153798 TI - Clinical experience with clozapine in psychoses. PMID- 4153799 TI - Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched sibling donors. PMID- 4153800 TI - [Medical practice in the future]. PMID- 4153801 TI - [Medical rehabilitation of patients with severe sequelae following trauma of the leg and foot]. PMID- 4153802 TI - Clinical studies of livedoid vasculitis: (segmental hyalinizing vasculitis). PMID- 4153803 TI - Physical therapy education: the future. PMID- 4153804 TI - Chemicals as tools in the study of excitable membranes. PMID- 4153805 TI - [Indication for surgery in congenital abnormalities of the urogenital system with special reference to the time of surgery]. PMID- 4153806 TI - [Anticlimax for the new H2 antagonist]. PMID- 4153807 TI - Multicore disease: report of a case with onset in middle age. PMID- 4153808 TI - Presidential address: Cancer as a specialty. Where have we been? PMID- 4153809 TI - Studies in dentifrices, 8: clinical testing of an acidulated, nongrinding dentifrice with reduced fluorine contents. PMID- 4153810 TI - Studies on new beta-adrenergic blocking agents. II. Syntheses and pharmacology of 2-anilinotropone derivatives. PMID- 4153811 TI - Studies on the amino acids of the tsetse fly, Glossina morsitans, maintained on in vitro and in vivo feeding systems. PMID- 4153812 TI - Studies on the gill of Mytilus edulis: the eu-latero-frontal cirri. PMID- 4153813 TI - Studies on the transport of L-tyrosine into an adrenergic clone of mouse neuroblastoma. PMID- 4153814 TI - Studies on the NADPH oxidizing activity in polymorphonuclear leucocytes. The mode of association with the granule membrane the relationship to myeloperoxidase and the interference of hemoglobin with NADPH oxidase determination. PMID- 4153816 TI - Vertigo in childhood. Comments on pathogenesis and management. PMID- 4153815 TI - Specificity of in vitro murine B cell activation by protein and polysaccharide polymers. PMID- 4153817 TI - Profile generalizability in the use of the MMPI with psychiatric inpatients. PMID- 4153818 TI - [Capillary hyperlactacidemia, criterion of exertion intolerance in patients treated with beta-blockaders]. PMID- 4153819 TI - Preliminary characterization studies on the Neisseria catarrhalis respiratory electron transport chain. AB - The Neisseria catarrhalis respiratory electron transport system was examined in a sonic type particulate membrane fraction and shown to have a moderately active succinate as well as nonpyridine nucleotide-dependent dl-lactate oxidoreductase and a very active tetramethyl-p-phenylenediamine oxidase. l-Malate and l glutamate oxidation were found to be dependent on pyridine nucleotides and exclusively associated with a soluble (or nonmembranous) fraction. The primary cytochrome components in the electron transport system appear to be c-type in nature (555 nm and 550 nm) as well as cytochrome a(1) (600 nm) and cytochrome o. PMID- 4153821 TI - The influence of capture and transportation on some blood parameters of fresh water fish. PMID- 4153820 TI - The incorporation of tritium in the body water and organic matter of selected marine invertebrates. PMID- 4153822 TI - The influence of serotonin, GABA and DL-dopa on the circadian rhythm in the toxicity of picrotoxin, pentylenetetrazol and phenobarbital in mice. PMID- 4153823 TI - Origins and evolution of the human malarias: the role of the vector. PMID- 4153825 TI - Symbiosis of the acoel flatworm Convoluta roscoffensis with the alga Platymonas convolutae. PMID- 4153824 TI - Physiological response to the submarine environment. PMID- 4153826 TI - Cardiovascular changes following DOCA-NaCl or conditioning in 6-hydroxydopamine treated rats. PMID- 4153827 TI - Cardiovascular histamine receptors in the rabbit. PMID- 4153829 TI - [Limitation of the free will in transitional syndromes]. PMID- 4153828 TI - Impairments in hormonal control of liver enzyme activity in aging rats. PMID- 4153830 TI - A critical assessment of methods for the determination of monoamine synthesis turnover rates in vivo. PMID- 4153831 TI - Sensitivity of restrained skipjack tuna (Katsuwonus pelamis) to abrupt increases in temperature. PMID- 4153832 TI - Sensitization and dishabituation in the cockroach. Main characteristics and localization of the changes in reactivity. PMID- 4153833 TI - Isocitric dehydrogenase activity in non-inflamed attached gingiva of rhesus monkeys. PMID- 4153834 TI - Longitudinal trend in prescribing psychotropic drugs. PMID- 4153835 TI - [Activity of NADP-producing enzymes in porcine adipose tissue. 1. Biopsy technic and enzyme tests as well as enzymatic differences between various anatomical locations of adipose tissue]. PMID- 4153836 TI - Uptake mechanisms for neurotransmitter amines. PMID- 4153837 TI - [Dyskinesia induced by anticholinergic drugs--electrophysiological analysis]. PMID- 4153838 TI - Renal sodium reabsorption in the hagfish, Eptatretus stouti. PMID- 4153839 TI - Regulation by salt and by Krebs cycle metabolites of citrate synthase from an osmoregulator, white shrimp, Penaeus setiferus, and from a non-osmoregulator, sea anemone, Bunedosoma cavernata. PMID- 4153840 TI - Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP. PMID- 4153841 TI - Modulation of corticotrophin-releasing factor release from hypothalamic synaptosomes. PMID- 4153842 TI - Regulation of larval corpora allata in Galleria mellonella. PMID- 4153843 TI - Regulation of lipogenesis in animal tissues. PMID- 4153844 TI - [Whole-body autoradiographic studies on the distribution and the placental transfer of fenoterol-hydrobromide (Th 1165a) in rats]. PMID- 4153845 TI - Problems associated with biological age. PMID- 4153846 TI - Problems associated with iontophoretic studies in the caudate nucleus and substantia nigra. PMID- 4153847 TI - Problems in interpreting neurochemical changes occurring in developing and aging animals. PMID- 4153849 TI - Familial progressive external ophthalmoplegia and ragged-red fibers. PMID- 4153848 TI - Completely isolated neurons in the mollusc, Lymnaea stagnalis. A new objective for nerve cell biology investigation. PMID- 4153850 TI - Simplified models of population dynamics of mosquitoes related to control technology. PMID- 4153851 TI - Forelimb blood flow and saliva spreading in the thermoregulation of the red kangaroo, Megaleia rufa. PMID- 4153852 TI - Ganglion blocking effect of indole alkaloids contained in Uncaria genus and Amsonia genus and related synthetic compounds on the rat superior cervical ganglion in situ. PMID- 4153853 TI - Facilitation of avoidance acquisition in the rat by ethanol and its abolition by alpha methyl p-tyrosine. PMID- 4153854 TI - Axially projected collagen structures. PMID- 4153855 TI - [Myelomeningocele. Development of upper urinary ways and importance of electro cysto-manometry]. PMID- 4153856 TI - [Prolongation of life expectancy in patients with gout through improved diagnosis and therapy]. PMID- 4153857 TI - Development of lipogenesis in rat brain cortex: the differential incorporation of glucose and acetate into brain lipids in vitro. PMID- 4153858 TI - Development of tumors as a result of graft-versus-host reaction. PMID- 4153859 TI - Developmental characteristics of phenylethanolamine and octopamine in the rat brain. PMID- 4153860 TI - 3-(Alpha-(tert-butylamino)methyl)-5-hydroxy-m-xylene-alpha, alpha'-diol, a selective bronchodilator. PMID- 4153861 TI - Results achieved with clozapine (leponex) in the treatment of neuroses. PMID- 4153862 TI - Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes. PMID- 4153863 TI - Hemolymph characteristics of developing adult tobacco hornworms reared as larvae on tobacco leaf or synthetic diet. PMID- 4153864 TI - The lymphocyte surface. I. Relation between Fc receptors, C'3 receptors and surface immunoglobulin. PMID- 4153865 TI - The lymphocyte surface. II. Separation of Fc receptor, C'3 receptor and surface immunoglobulin-bearing lymphocytes. PMID- 4153866 TI - Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-receptor antagonists. PMID- 4153867 TI - Pharmacological properties of a potential tranquilising agent mesylphenacyrazine. I. Interaction with drugs influencing the nervous system. PMID- 4153868 TI - Pharmacology of aconitine-induced automaticity on in vitro cat myocardial preparations. II. Effects of refractory period prolongation, reduced sodium and tetrodotoxin. PMID- 4153870 TI - Chromatography of the 1,4-benzodiazepines. PMID- 4153871 TI - [Dermatological colloquium at the Munster University Dermatological Clinic, December 12, 1973. Case demonstrations]. PMID- 4153869 TI - Pharmacology of the adrenergic mechanism. PMID- 4153872 TI - The maturation of indoleamine metabolism in the lateral eye of the mouse. PMID- 4153873 TI - Enzyme localization in the anaerobic mitochondria of Ascaris lumbricoides. AB - Mitochondria from the muscle of the parasitic nematode Ascaris lumbricoides var. suum function anaerobically in electron transport-associated phosphorylations under physiological conditions. These helminth organelles have been fractionated into inner and outer membrane, matrix, and intermembrane space fractions. The distributions of enzyme systems were determined and compared with corresponding distributions reported in mammalian mitochondria. Succinate and pyruvate dehydrogenases as well as NADH oxidase, Mg(++)-dependent ATPase, adenylate kinase, citrate synthase, and cytochrome c reductases were determined to be distributed as in mammalian mitochondria. In contrast with the mammalian systems, fumarase and NAD-linked "malic" enzyme were isolated primarily from the intermembrane space fraction of the worm mitochondria. These enzymes are required for the anaerobic energy-generating system in Ascaris and would be expected to give rise to NADH in the intermembrane space. The need for and possible mechanism of a proton translocation system to obtain energy generation is suggested. PMID- 4153874 TI - Sedimentation velocities of cells mediating two different GVH lesions. PMID- 4153875 TI - The metabolism of carbohydrates by extremely halophilic bacteria: glucose metabolism via a modified Entner-Doudoroff pathway. PMID- 4153877 TI - Parameters of oxygen delivery in the species Marmota flaviventris: at sea level and 12,000 feet. PMID- 4153876 TI - The metabolism of some thioureidobenzene fungicides in mice and sheep. PMID- 4153878 TI - Dynamics of transmissional ultrastructures in sympathetic neurones on the rat. PMID- 4153879 TI - Dopamine-beta-hydroxylase and the regulation of the noradrenergic neuron. PMID- 4153880 TI - Dopaminergic neurons: drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow. PMID- 4153881 TI - [Permissive effect of hydrocortisone on serine dehydratase induction by glucagon in rat liver; comparison with tyrosine aminotransferase]. PMID- 4153882 TI - Pneumococci relatively insensitive to penicillin in Australia and New Guinea. PMID- 4153884 TI - [Pulmonary eosinophilia]. PMID- 4153883 TI - Thermodynamic relationships in mitochondrial oxidative phosphorylation. PMID- 4153885 TI - [Haemophilus influenza and chronic bronchitis. Our experience of the last 3 years (1970-1973)]. PMID- 4153886 TI - [Tremor and motility following oxotremorine and harmine in rats with lesions of the nigro-striatal system]. PMID- 4153887 TI - Thermoregulation in crocodilians. I. Head-body temperature control in the papuan New Guinean crocodiles, Crocodylus novaeguinea and Crocodylus porosus. PMID- 4153888 TI - A comparative study of acute myocardial infarction in the rabbit, cat and man. PMID- 4153889 TI - A comparison of the effects of GABA and imidazoleacetic acid on the membrane conductance of lobster muscle fibres. PMID- 4153890 TI - An improved synthesis of thyrotropin releasing hormone (TRH) and crystallization of the tartrate. PMID- 4153891 TI - An improved NADH-dependent transketolase assay for assessing thiamine nutriture. PMID- 4153892 TI - Minimum duration of trans-synaptic stimulation required for the induction of tyrosine hydroxylase by reserpine in the rat superior cervical ganglion. PMID- 4153893 TI - [When is "addiction" interpreted as a pathological disorder of mental process in the sense of paragraph 169 of the (insurance Contract Act) VVG?]. PMID- 4153894 TI - Coronary artery aneurysms in a 9-year-old child. PMID- 4153895 TI - Perinatal drug metabolism and morphological changes in the hepatocytes of normal and phenobarbital-treated guinea pigs. PMID- 4153896 TI - Absence of involvement of glutamine synthetase and of NAD-linked glutamate dehydrogenase in the nitrogen catabolite repression of arginase and other enzymes in Saccharomyces cerevisiae. PMID- 4153897 TI - Enhanced phagocytic capacity. The biologic basis for the elevated histochemical nitroblue tetrazolium reaction. AB - The biologic basis for the elevated histochemical reduction of nitroblue tetrazolium dye (NBT) in neutrophils from patients with acute bacterial infection or polycythemia vera was studied. A precipitin reaction followed mixing NBT with heparin. NBT was reduced after phagocytosis of this complex (H-NBT) by polymorphonuclear leukocytes (PMNs). Ingestion required divalent cations and was facilitated by the presence of complement. H-NBT incubated with normal but not with C2-deficient human serum converted native C3 to its inactive form. Phagocytic indices were determined in patients and controls by measuring O(2) utilization and hexose monophosphate shunt activity and by visually counting cell associated latex particles. Significant elevations above controls were observed in phagocytes isolated from all patients with elevated histochemical NBT scores when H-NBT complex, latex, or zymosan was employed as the phagocytic particle. Increased indices were observed in the presence of fresh AB serum, heat inactivated AB serum, or without serum. Serum from patients with elevated NBT scores did not alter phagocytosis in control phagocytes. With NADH and NADPH as substrates, total NBT diaphorase activity of sonicated leukocytes was normal in all patients. These results suggest that increased phagocytic capacity of PMNs is the primary cause of increased histochemical NBT reduction. The PMNs of patients with acute bacterial infection or polycythemia vera may have alterations in their cell membranes which lead to an enhanced rate of phagocytosis. PMID- 4153898 TI - Adrenergic agents. 2. Synthesis and potential beta-adrenergic agonist activity of some ring-chlorinated relatives of isoproterenol. PMID- 4153899 TI - [Clinical and roentgenological evaluation of fractures of the distal end of the radius]. PMID- 4153900 TI - [Clinical contribution in the treatment of paroxysmal tachycardia]. PMID- 4153901 TI - [Clinical evaluation of Bromazepam with special reference to obsessive syndromes and phobias]. PMID- 4153902 TI - [Clinical trial of an original therapeutic agent in rhinopharyngeal diseases]. PMID- 4153903 TI - [Clinical use of certain beta-blockaders]. PMID- 4153904 TI - Planning cooperation in human bone marrow transplant research. A report of the special meeting of the cooperative group on bone marrow transplantation in man, September 23, 1972, Wingspread, Racine, Wisconsin. PMID- 4153905 TI - [Amino acid level in albino rat brain and liver tissue during acute brain edema]. PMID- 4153907 TI - Immunologic activation of murine leukemia viruses. PMID- 4153906 TI - Ethanol oxidation by components of rat liver microsomes. PMID- 4153908 TI - Immunologic theory of aging: current status. PMID- 4153909 TI - Immunological activation of oncogenic viruses: interrelationship of immunostimulation and immunosuppression. PMID- 4153910 TI - Immunopathology of viral hepatitis in man. PMID- 4153911 TI - Desensitization by leg contact in the cockroach: localization of the reactivity changes and a study of their possible sensory origin. PMID- 4153912 TI - [Transpostion of the duodenum in acute dilation of the stomach]. PMID- 4153914 TI - [Quantitative determination of nanophyne by a photometric extraction method]. PMID- 4153913 TI - Reconstitution of light-dependent electron transport in membranes from a bacteriochlorophyll-less mutant of Rhodopseudomonas spheroides. PMID- 4153915 TI - A controlled comparison of chlorazepate with oxazepam in neurotic anxiety. PMID- 4153916 TI - An investigation of the neural mechanisms controlling the colour change responses of the dogfish, Scyliorhinus canicula L. by mesencephalic and diencephalic lesions. PMID- 4153917 TI - Amino acid and serotonin content in the nervous system, muscle and blood of the cockroach Periplaneta americana. PMID- 4153918 TI - Androblastoma--sertoli cell tumor. PMID- 4153919 TI - Photochemical activity and components of membrane preparations from blue-green algae. I. Coexistence of two photosystems in relation to chlorophyll a and removal of phycocyanin. PMID- 4153920 TI - Histochemical and tissue culture studies of dystrophic and experimentally denervated animal muscle. PMID- 4153921 TI - Dissociation of the effect of adrenalin on glucose uptake from that on adenosine cyclic 3',5'-monophosphate levels and on lipolysis in rat-isolated fat cells. PMID- 4153923 TI - [Blood-sucking arthropods in protected natural areas. I. The Circeo National Park]. PMID- 4153922 TI - [Endocrine function of the testis in 125 cases of cryptorchism]. PMID- 4153924 TI - [Cytoenzymological caracterization of cells from human skin melanoma in culture]. PMID- 4153925 TI - Use of the MMPI with patients with recent war-related head injuries. PMID- 4153926 TI - Hydrogen ion activity in polychaete body fluids. PMID- 4153927 TI - Photoinactivation of NAD-glucohydrolase from rabbit heart. PMID- 4153929 TI - Welcome address: 49th all-India medical conference. PMID- 4153928 TI - [Etiology, clinical aspects, differential diagnosis and therapy of neurovirus infections]. PMID- 4153930 TI - Seasonal anaemia in the Rottnest quokka, Setonix brachyurus (Quoy & Gaimard) (Marsupialia; Macropodidae). PMID- 4153933 TI - Personality correlates of visual perceptual responses. PMID- 4153932 TI - Regional variation in alanine absorption in the gut of Echinus esculentus. PMID- 4153934 TI - Personality type, reports of violence, and aggressive behavior. PMID- 4153936 TI - [Chronic bronchitis and life expectancy]. PMID- 4153935 TI - Pulmonary ascorbic acid loss induced by catecholamines. PMID- 4153937 TI - [Chronicle of the Swiss University Dental Schools, 1973]. PMID- 4153938 TI - Response of dermal melanophores to epinephrine after removal of the epidermal barrier. PMID- 4153939 TI - Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450. PMID- 4153940 TI - [Lipophilic anions--new class of hydroxylation reaction inhibitors]. PMID- 4153941 TI - Neuropsychopharmacology of monoamines and their regulatory enzymes. PMID- 4153943 TI - Editorial: Histamine H2-receptor antagonists, gastric secretion and duodenal ulcer. PMID- 4153942 TI - Evaporative water loss and tissue dehydration of hamsters in the heat. PMID- 4153944 TI - Editorial: Hypertensive crises in pregnancy. PMID- 4153945 TI - Editorial: Penicillin-resistant pneumococci and pneumonia. PMID- 4153946 TI - Editorial: Report of the Committee on Contrast Media of the International Society of Radiology. PMID- 4153947 TI - Editorial: Shrinking the myocardial infarct. PMID- 4153948 TI - Factors affecting the biochemical maturation of the brain. Effect of undernutrition during early life. PMID- 4153949 TI - Factors associated with failure of lumbar spine fusion. PMID- 4153951 TI - Purpose-in-life and the Eysenck personality inventory. PMID- 4153950 TI - [Report on Working Group 6 at the Internal Working Session of the DPG (German Psychoanalytical Society) in Berlin, Oct. 26-8, 1973]. PMID- 4153952 TI - Glucose-6-phosphate dehydrogenase: comparison of kinetic contants among different breeds of sheep. PMID- 4153953 TI - A cross-validation of seventeen experimental MMPI scales related to antisocial behavior. PMID- 4153954 TI - Testosterone formation in testis of the immature androgen insensitive pseudohermaphrodite male rat (Stanley-Gumbreck rat). PMID- 4153955 TI - Neurotransmitter synthesis by two clonal nerve cell lines: changes with culture growth and morphological differentiation. PMID- 4153956 TI - Improved oral health of schoolchildren of 16 communities after 8 years of prevention. I. Combining DMF data from the communities. PMID- 4153958 TI - Group therapy with obese women of varying MMPI profiles. PMID- 4153957 TI - Hydroxylations of bile acids by reconstituted systems from rat liver microsomes. PMID- 4153959 TI - [Comparative effects of several beta-adrenergic inhibitors on pulmonary resistance in guinea pigs]. PMID- 4153960 TI - [Comparative studies and therapeutic possibilities of midodrin (Gutron) in the hypotensive syndrome]. PMID- 4153961 TI - [Comparison of muscular histoenzymological and electromyographic findings in human neuromuscular pathology. Methods and preliminary results]. PMID- 4153962 TI - The pathology of bone marrow transplantation. PMID- 4153963 TI - The personality in psychomotor epilepsy compared with the explosive and aggressive personality. PMID- 4153964 TI - [Morphohistochemical changes in the central and peripheral nervous system in periarteritis nodosa]. PMID- 4153965 TI - [Morphological studies of skeletal muscle injuries caused by blunt force impact. I. Light microscopy]. PMID- 4153966 TI - [Morphological studies of skeletal muscle injuries caused by blunt force impact. II. Electron microscopy and electron microscopic histochemical studies]. PMID- 4153967 TI - A rapid, simple method for the isolation of rat brain microsomes. PMID- 4153968 TI - Relapsing pneumococcal meningitis: isolation of an organism with decreased susceptibility to penicillin G. PMID- 4153969 TI - The psychotherapy of schizophrenia. PMID- 4153970 TI - Synaptochemistry. Outlines and scope of a discipline. PMID- 4153971 TI - [Symptoms, diagnosis and prognosis of amyloidoses]. PMID- 4153972 TI - Water balance of a euryhaline sea anemone, Diadumene leucolena. PMID- 4153973 TI - Contractile actions of antihistamines on isolated arterial smooth muscle. PMID- 4153974 TI - Contractile properties of muscle: control by pattern of muscle activity in the rat. PMID- 4153975 TI - Interaction of hydrocortisone and dibutyryl cyclic AMP in the induction of tyrosine amino-transferase and phosphoenolpyruvate carboxy-kinase in rat liver. PMID- 4153976 TI - Interactions between oxidative metabolism and acid secretion in gastric mucosa. PMID- 4153977 TI - Central action of bicuculline. PMID- 4153978 TI - An oral health survey of Manono-tai, Western Samoa. PMID- 4153979 TI - [Therapy and treatment results of undescended testes]. PMID- 4153980 TI - Alteration of psychosomatic reactivity after a single therapeutic dose of pentobarbital in relation to the sex of probands. PMID- 4153981 TI - Maturational changes in the ovarian lipid spectrum of the pink shrimp, Penaeus duorarum duorarum Burkenroad. PMID- 4153982 TI - A direct radioimmunoassay for mouse casein. PMID- 4153983 TI - Osmoregulatory responses to DDT and varying salinities in Salmo gairdneri. I. Gill Na-K-ATPase. PMID- 4153984 TI - The respiration in air and in water of the limpets Patella caerulea (L.) and Patella lusitanica (Gmelin). PMID- 4153985 TI - The response of "obese" (ob-ob) and "diabetic" (db-db) mice to treatments that influence body temperature. PMID- 4153986 TI - Suppression of erythropoiesis by simultaneous proliferation of alloantigen sensitive units. PMID- 4153987 TI - Suppression of graft-versus-host reaction in rats by cell-free extract from heterologous liver. PMID- 4153988 TI - Allergic headaches. PMID- 4153989 TI - Synergistic actions of nitrite-beta-adrenergic blocking agents in the therapy of angina pectoris. Pharmacologic and therapeutic rationale. PMID- 4153990 TI - Distribution of the enzymes involved in the disposal of arginine and ornithine in different regions of rat brain. PMID- 4153991 TI - Inheritance of the Aarskog syndrome. PMID- 4153992 TI - [Pharmacology of izoktamil]. PMID- 4153993 TI - Determination of clonazepam and flunitrazepam in blood by electron-capture gas liquid chromatography. PMID- 4153994 TI - Interneuronal activity as a factor interfering with the interpretation of results from microiontophoretic studies. PMID- 4153995 TI - [Steroid production in the testis]. PMID- 4153996 TI - Control of utero-ovarian and peripheral venous plasma progesterone by beta sympathomimetic drugs in pregnant sheep. PMID- 4153997 TI - The role of estrogens in primate reproduction: a Brook Lodge workshop. PMID- 4153998 TI - The role of histamine receptors in the stimulation of gastric acid secretion. PMID- 4153999 TI - The role of phosphotransferase-mediated syntheses of fructose 1-phosphate and fructose 6-phosphate in the growth of Escherichia coli on fructose. PMID- 4154000 TI - The role of physicians' assistants in a university teaching service. PMID- 4154001 TI - Environmental modification of mammalian drug metabolism and biological response. PMID- 4154002 TI - Expert group on drugs in modern society: community reactions to drug use by young people. PMID- 4154003 TI - Observations on the amphibian "diaphragm". PMID- 4154004 TI - [Does fright or "mental shock" represent physical injury in the sense of paragraph 823 part 2 of the Federal Law Book?]. PMID- 4154005 TI - Bends in fish. PMID- 4154006 TI - Dye-salt formation as a general method for colorimetric determination of antihistaminics. I. The use of methyl orange for the determination of chlorphenamine, diphenhydramine and chloropyramine in pharmaceutical preparations. PMID- 4154007 TI - Dye salt formation as a general method for colorimetric determination of antihistaminics. Part 2: Spectrophotometric determination of thenalidine maleate and thiazinamium methylsulphate in pure and dosage forms. PMID- 4154008 TI - The scientific background of the International Sanitary Conferences, 1851--1938. 3. PMID- 4154009 TI - A case of true hermaphroditism presenting as an undescended testicle. PMID- 4154010 TI - [Possibilities of predicting the effect of surgical vagotomy]. PMID- 4154012 TI - Transmitter release induced by a 'factor' in rabbit serum. PMID- 4154011 TI - [Sepsis and hemolytic-uremic-syndrome (author's transl)]. PMID- 4154013 TI - [Physostigmine as an analeptic in Flos daturae anesthesia. Clinical analysis of 2,300 cases]. PMID- 4154014 TI - Assessment of plasma glutamyl transpeptidase activity and urinary D-glucaric acid excretion as indices of enzyme induction. PMID- 4154015 TI - [First reduce infant mortality, then family planning]. PMID- 4154016 TI - [Anesthesia in ambulatory bronchoscopy in patients with pulmonary tuberculosis]. PMID- 4154017 TI - The structure of somatic and psychic neurotic symptoms in prisoner-toxicomans. PMID- 4154018 TI - Trait interrelations in implicit personality theories and questionnaire data. PMID- 4154019 TI - Short- and long-term regulation of tyrosine hydroxylase. PMID- 4154020 TI - Short-term control of tyrosine hydroxylase. PMID- 4154021 TI - Graft-versus-host disease. Modification with concanavalin A. PMID- 4154022 TI - Graft-versus-leukemia. V. Absence of antileukemic effect using allogeneic h-2 identical immunocompetent cells. PMID- 4154023 TI - [Instable block of the left branch and with paroxysmal onset. Treatment with beta adrenergic blockaders (1 case)]. PMID- 4154024 TI - [Dental caries in 5-, 7-and-9-year-old children in The Hague in 1969 and 1972]. PMID- 4154025 TI - [Mental disorders after limb injury]. PMID- 4154026 TI - PTC tasting and dental caries. PMID- 4154027 TI - Low temperature studies of microsomal cytochrome P450. Release of oxidizing species. PMID- 4154028 TI - Maintenance treatment of schizophrenia with long-acting fluphenazine. PMID- 4154030 TI - [Letter: Therapy and prognosis of hypospadia?]. PMID- 4154029 TI - [Letter: Inhibitor of H 2 histamine receptors and the Zollinger-Ellison syndrome]. PMID- 4154031 TI - [Rhythmic fluctuations in the lumen of isolated arteries during simultaneous stimulation of alpha- and beta-adrenoreceptors]. PMID- 4154032 TI - Genetic aspects of monoamine mechanisms. PMID- 4154033 TI - Meiotic duration in wheat genotypes with or without homoeologous meiotic chromosome pairing. PMID- 4154034 TI - Hepatic tryptophan oxygenase activity as a marker of changes in protein metabolism during chronic ethanol treatment. PMID- 4154035 TI - Genetical analysis of fructose utilization by Escherichia coli. PMID- 4154036 TI - [Critical deliberations on psychoanalytical continuing education]. PMID- 4154037 TI - [Tactical error in the surgical treatment of multiple injuries of a single extremity]. PMID- 4154038 TI - Identification and differentiation of organic medicinal agents. VII. Some newer antihistamines and a miscellaneous group of drugs. PMID- 4154040 TI - Relation of the second messenger system to the electrogenesis and regulation of the contraction in the heart cell membrane of insecta. PMID- 4154039 TI - Nicotinamide adenine dinucleotide phosphate-dependent formate dehydrogenase from Clostridium thermoaceticum: purification and properties. AB - The nicotinamide adenine dinucleotide phosphate (NADP)-dependent formate dehydrogenase in Clostridium thermoaceticum used, in addition to its natural electron acceptor, methyl and benzyl viologen. The enzyme was purified to a specific activity of 34 (micromoles per minute per milligram of protein) with NADP as electron acceptor. Disc gel electrophoresis of the purified enzyme yielded two major and two minor protein bands, and during centrifugation in sucrose gradients two components of apparent molecular weights of 270,000 and 320,000 were obtained, both having formate dehydrogenase activity. The enzyme preparation catalyzed the reduction of riboflavine 5'-phosphate flavine adenine dinucleotide and methyl viologen by using reduced NADP as a source of electrons. It also had reduced NADP oxidase activity. The enzyme was strongly inhibited by cyanide and ethylenediaminetetraacetic acid. It was also inhibited by hypophosphite, an inhibition that was reversed by formate. Sulfite inhibited the activity with NADP but not with methyl viologen as acceptor. The apparent K(m) at 55 C and pH 7.5 for formate was 2.27 x 10(-4) M with NADP and 0.83 x 10(-4) with methyl viologen as acceptor. The apparent K(m) for NADP was 1.09 x 10(-4) M and for methyl viologen was 2.35 x 10(-3) M. NADP showed substrate inhibition at 5 x 10(-3) M and higher concentrations. With NADP as electron acceptor, the enzyme had a broad pH optimum between 7 and 9.5. The apparent temperature optimum was 85 C. In the absence of substrates, the enzyme was stable at 70 C but was rapidly inactivated at temperatures above 73 C. The enzyme was very sensitive to oxygen but was stabilized by thiol-iron complexes and formate. PMID- 4154041 TI - Fractionation of the electron-transport chain of Escherichia coli. PMID- 4154042 TI - Relationship between antihistamic activity and plasma level of diphenhydramine. PMID- 4154043 TI - Relationship of Streptococcus mutans carrier status to the development of carious lesions in initially cariesfree recruits. PMID- 4154044 TI - [Aortitis syndrome--Takayashu arteriitis in young women]. PMID- 4154045 TI - Reactivation of immunocompetence in spleen cells of aged mice. PMID- 4154046 TI - Inactivation of nitrate reductase by NADH in Nitrobacter agilis. PMID- 4154047 TI - Adaptive phenomena in bone marrow transplantation. PMID- 4154048 TI - [Histochemistry of the key oxidoreductases and lysosomal enzymes in the tonsils and other lyphoid formations in rabbits in experimental allergy]. PMID- 4154049 TI - Nematode biochemistry. XIII. Peroxisomes in the free-living nematode, Turbatrix aceti. PMID- 4154050 TI - Hematological values of some great flying and aquatic-diving birds. PMID- 4154051 TI - Electrically induced relaxation in systematic desensitization: a case note. PMID- 4154052 TI - [Controlled hypotension in neurosurgery]. PMID- 4154053 TI - Peritrophic membranes in the midgut of pupal and pre-blood meal adult mosquitoes (Diptera: Culicidae). PMID- 4154054 TI - Electrophoretic studies on gene-enzyme systems in mosquitoes (Diptera, Culicidae). PMID- 4154055 TI - The type-specific substance from Pneumococcus type 33B. AB - 1. The type-specific substance, S. 33B, from Pneumococcus type 33B contains P, 2.89; hexose, 51; total sugar, 69; galactosamine, 18; and d-glucose, 20%. 2. After degradation with alkali, followed by enzymic dephosphorylation, S. 33B yielded a hexasaccharide. 3. The hexasaccharide was assigned the structure O-beta d-glucopyranosyl- (1-->5)-O-beta-d-galactofuranosyl- (1-->3)-O-2-acetamido-2 deoxy-beta-d- galactopyranosyl-(1-->4)-O-[alpha-d- galactopyranosyl-(1-->2)] alpha-d-galactopyranosyl- (1-->2)-ribitol. 4. Phosphate residues in S. 33B are located on the hydroxyl groups at position 5 of ribitol units and on the hydroxyl groups at position 6 of hexopyranose residues. PMID- 4154056 TI - Evaluation of a fluoride prophylaxis paste in a fluoridated community. PMID- 4154057 TI - A double-blind study on the effects of piracetam upon perceptual and psychomotor performance at varied heart rates in patients treated with artificial pacemakers. PMID- 4154058 TI - [Abduction contracture of the shoulder joint as a consequence of isolated fibrosis of the deltoid muscle]. PMID- 4154059 TI - Rescue from canine graft-versus-host reaction by autologous or DL-A-compatible marrow. PMID- 4154060 TI - [Value of enzyme tests in the diagnosis of toxic hepatocellular damage]. PMID- 4154062 TI - Influence of dietary fatty acids on the composition of plasma fatty acids in the tundra wolf (Canis lupus tundrarum). PMID- 4154061 TI - Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex. PMID- 4154064 TI - Influence of noncholinergic drugs on rat striatal acetylcholine levels. PMID- 4154063 TI - Influence of morphine and naloxone on the release of noradrenaline from rat brain cortex slices. PMID- 4154065 TI - Influence of periodicity of eating on intestinal glycolytic enzymes in the rat. PMID- 4154066 TI - Influence of the cardiac sympathetics on left ventricular dynamics during tachycardia. PMID- 4154067 TI - Influence of GABA and glycine and their antagonists on inhibitory mechanisms of pigeon's optic tectum. PMID- 4154069 TI - [Simultaneous application of a beta-adrenergic sympathicomimetic and beta adrenergic antagonist during inhibition of labor (author's transl)]. PMID- 4154070 TI - [Serum glutamyl transpeptidase (GGTP) in chronic alcoholism]. PMID- 4154068 TI - Convulsant drugs: amino acid antagonism and central inhibition. PMID- 4154071 TI - [Immunosuppression and induction of tolerance by 3-(2-chloroethyl)-2(2 mesyloxyethylamino)-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide (ASTA 5122)]. PMID- 4154072 TI - [Immunosuppressive therapy]. PMID- 4154073 TI - Measurement of inorganic pyrophosphate in biological fluids and bone tissues. PMID- 4154074 TI - The use of systemic immunity adjuvants in the prophylaxis or therapy of cancer. PMID- 4154075 TI - The utilization of physician assistants in geographically remote areas. PMID- 4154076 TI - Evolutionary aspects of transmitter heterogeneity. PMID- 4154077 TI - The value of blood culture in the diagnosis of pneumococcal pneumonia. PMID- 4154078 TI - Activation of methionine synthetase by a reduced triphosphopyridine nucleotide dependent flavoprotein system. PMID- 4154079 TI - Activation of NADH oxidase by succinate in partially ubiquinone-depleted submitochondrial particles. PMID- 4154081 TI - The vertical distribution of mosquitoes flying over open farmland in the Gambia. PMID- 4154080 TI - Active chloride transport across the skin of the earthworm, Lumbricus terrestris L. PMID- 4154082 TI - Arbovirus studies in Houston, Texas, 1968-1970. PMID- 4154083 TI - [Heavy intoxication as a side-effect of CARBROMAL in two children (author's transl)]. PMID- 4154084 TI - Overwintering of arboviruses. PMID- 4154085 TI - Redox changes of cytochrome alpha-607 and NAD(P)H in rat liver mitochondria induced by L-malate under anaerobic conditions. PMID- 4154086 TI - [Unexpected complications by anticholinergics contained in hypnotics and analgesics]. PMID- 4154087 TI - Takayasu's arteritis. An angiographic study with remarks on ethnic distribution in Israel. PMID- 4154088 TI - Delayed secondary disease in mice after early or late therapy with anti-thymocyte serum. PMID- 4154089 TI - Acetyl coenzyme A carboxylase system of Escherichia coli. Purification and properties of the biotin carboxylase, carboxyltransferase, and carboxyl carrier protein components. PMID- 4154090 TI - Acetyl coenzyme A carboxylase system of Escherichia coli. Site of carboxylation of biotin and enzymatic reactivity of 1'-N-(ureido)-carboxybiotin derivatives. PMID- 4154091 TI - Acetyl coenzyme A carboxylase system of Escherichia coli. Studies on the mechanisms of the biotin carboxylase- and carboxyltransferase-catalyzed reactions. PMID- 4154092 TI - Acetyl coenzyme A carboxylase. PMID- 4154093 TI - Acetylcholine levels in the frog spinal cord following the administration of different convulsants. PMID- 4154094 TI - [Enzyme histochemical investigation for the influence of the experimental cryptorchism by the dystopic and orthotopic dog testis (author's transl)]. PMID- 4154095 TI - Biosynthesis of free amino acids in the brain of Jimpy mice. PMID- 4154096 TI - [Benzodiazepine-propanidid association in analgesia during labor (preliminary note)]. PMID- 4154097 TI - The APUD cell concept and its implications in pathology. PMID- 4154098 TI - NADPH-dependent oxidation of methanol, ethanol, propanol and butanol by hepatic microsomes. PMID- 4154100 TI - [Detection and gas-chromatographic identification of benzodiazepine tranquilizing agents in biological material (serum, urine, gastric content) in acute poisonings]. PMID- 4154099 TI - [COMPLARATIVE CHARACTERISTICS OF THE CLINICAL EFFECTS OF TRANQUILIZERS]. PMID- 4154101 TI - Mechanistic studies of glutamine synthetase from Escherichia coli. Fluorometric identification of a reactive intermediate in the biosynthetic reaction. PMID- 4154102 TI - The effect of histidine modification on the activity of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli B. PMID- 4154103 TI - Interaction of S-100 protein with cations and liposomes. PMID- 4154104 TI - Bioluminescence in coelenterates. PMID- 4154105 TI - Redox potentiometry in mitochondrial and photosynthetic bioenergetics. PMID- 4154106 TI - The respiratory system of the marine bacterium Beneckea natriegens. II. Terminal branching of respiration to oxygen and resistance to inhibition by cyanide. PMID- 4154107 TI - Non-pyridine nucleotide dependent L-(plus)-glutamate oxidoreductase in Azotobacter vinelandii. PMID- 4154108 TI - Biosynthesis of fatty acids in vitro by homogenate of developing rat brain: desaturation and chain-elongation. PMID- 4154109 TI - Purification of gamma-glutamyltransferase of rat kidney by affinity chromatography using concanavalin A conjugated with sepharose 4B. PMID- 4154110 TI - Long-term perfusion of the isolated rat liver: maintenance of its functional state by use of a fluorocarbon emulsion. PMID- 4154111 TI - Changes in cell permeability following a marked reduction of saturated fatty acid content of Escherichia coli K-12. PMID- 4154112 TI - [Effect of electron transport on chlorophyll fluorescence yield in chloroplasts]. PMID- 4154113 TI - [Bloodsucking mosquitoes (Diptera, Culicidae) of the shores of the White Sea. I. A review of the species]. PMID- 4154114 TI - Theoretical implications of drug-induced adaptive regulation for a biogenic amine hypothesis of affective disorder. PMID- 4154115 TI - The pupae of vector mosquitoes. PMID- 4154117 TI - Prostaglandins, kinin and inflammation in the rat. AB - 1 Prostaglandin E(1) and bradykinin exert synergistic effects on vascular permeability in rat skin and in rat paws. Prostaglandin E(2) is inactive in this respect.2 Prostaglandin F(2alpha) reduces the bradykinin response in rat skin but not in rat paws. It also markedly reduces the response of the skin to dextran, 5 hydroxytryptamine and histamine.3 Prostaglandin E(1) and dextran exert synergistic effects in rat skin when threshold doses of each agent are used.4 Rats genetically resistant to dextran fail to respond to intradermal dextran in the presence of prostaglandin E(1). PMID- 4154116 TI - Depolarizing actions of gamma-aminobutyric acid and related compounds on rat superior cervical ganglia in vitro. AB - 1 Potential changes in rat superior cervical ganglia were recorded in vitro with surface electrodes.2 gamma-aminobutyric acid (GABA) produced a transient, low amplitude ganglion depolarization at rest, and a transient hyperpolarization in ganglia depolarized by carbachol. Depolarization was not prevented by preganglionic denervation. The log dose-response curve for depolarization was sigmoid with a mean ED(50) of 12.5 muM.3 The ganglion was depolarized in similar manner by the following compounds (mean molar potencies relative to GABA (=1) in brackets): 3-aminopropane sulphonic acid (3.4), gamma-amino-beta-hydroxybutyric acid (0.27), beta-guanidino-propionic acid (0.12), guanidinoacetic acid (0.057), delta-aminovaleric acid (0.048), beta-alanine (0.01), 2,4-diaminobutyric acid, gamma-guanidinobutyric acid, taurine and N-methyl-GABA (all <0.01). The following compounds did not depolarize the ganglion at 10 mM concentrations: alpha- and beta-amino-n-butyric acids, alpha-amino-iso-butyric acid, glycine and glutamic acid.4 Depolarization declined in the continued presence of GABA. Ganglia thus ;desensitized' to GABA showed a diminished response to other amino acids but not to carbachol.5 The effect of GABA was not antagonized by hyoscine and hexamethonium in combination, in concentrations sufficient to block responses to carbachol.6 Responses to GABA were blocked more readily than those to carbachol by bicuculline (IC(50), 14 muM) and picrotoxin (IC(50), 37 muM). Strychnine (IC(50), 73 muM) was a relatively weak and less selective GABA-antagonist.7 It is concluded that sympathetic ganglion cells possess receptors for GABA and related amino acids which are (a) different from the acetylcholine receptors and (b) similar to GABA receptors in the central nervous system. PMID- 4154118 TI - Blood muramidase activity in colorectal cancer. AB - The serum muramidase levels were measured in 128 patients with primary or metastatic colorectal cancer, 166 tumour-free patients after resection of a colorectal cancer, and 172 controls. Muramidase levels over 10 mug/ml were detected in 30%-39% of the tumour-bearing patients, in 8.2% of the tumour free, and in only 1.7% of the controls (normal level 6.68 +/- 1.42 mug/ml). Long-term follow up indicated that raised levels may occur as a transient phenomenon in recurrent or metastatic disease. The likely relation of abnormal serum muramidase activity and stimulation of the reticuloendothelial system is discussed. PMID- 4154119 TI - Letter: Beta-adrenergic blocking agents in patients with renal failure. PMID- 4154120 TI - Letter: Hypertension and myocardial infarction. PMID- 4154121 TI - Prevention of exercise-induced asthma by indoramin. AB - Indoramin, an alpha-adrenoceptor blocking drug, has been found to prevent the occurrence of exercise-induced bronchoconstriction. Evidence is provided in two cases that this was not due to the antihistamine properties of indoramin. PMID- 4154122 TI - Prenatal diagnosis of galactosaemia. AB - We have monitored two pregnancies from families at risk for galactosaemia. The fetus was diagnosed as having galactosaemia in one and to be unaffected in the other. The accuracy of the predictions was confirmed postnatally. Assays for galactose 1-phosphate uridyl transferase involving the reduction of the coenzymes NAD or NADP are unsuitable for amniotic cells whereas estimation of (14)C-UDP galactose produced from (14)C-galactose 1-phosphate detected the homozygous mutant fetus. PMID- 4154123 TI - Letter: Alpha-adrenoceptor-blocking drugs in asthma. PMID- 4154124 TI - Bites by the saw-scaled or carpet viper (Echis carinatus): trial of two specific antivenoms. AB - Echis carinatus is the most important cause of morbidity and mortality from snake bite in Nigeria and in many other parts of the world. Forty-six patients with systemic poisoning by this snake were given echis antivenom made either by the South African Institute for Medical Research (S.A.I.M.R.) or by Behringwerke (North and West African polyvalent antivenom). A simple test of blood coagulability was used to assess whether an adequate neutralizing dose of antivenom had been given. An average of 15.2 ml S.A.I.M.R. antivenom restored normal coagulability permanently in all 23 patients in one group, but in the other group receiving an average dose of 37.9 ml Behringwerke antivenom normal clotting resulted in only 18 out of 23 patients. Local tissue swelling was similar in both groups, but local necrosis occurred in three patients treated with Behringwerke antivenom and in none given S.A.I.M.R. antivenom. PMID- 4154126 TI - [Symposium on hypertension and beta receptor blockade: introduction]. PMID- 4154125 TI - Letter: Agoraphobia. PMID- 4154128 TI - NADP-dependent isocitrate dehydrogenase from rat brain cytosol. PMID- 4154127 TI - Beta blockers in hypertension. PMID- 4154129 TI - [Obtaining microsomes by coprecipitation with Ca2+ and demonstration of enzyme induction using phenobarbital]. PMID- 4154130 TI - [Influence of the mode of anesthesia on the activity of a quick-acting curarimimetic, AH 8165]. PMID- 4154132 TI - [Effect of splanchnic nerve section on the rate of adrenal dopamine renewal in rats subjected to forced swimming]. PMID- 4154131 TI - [Effects of adrenaline and various alpha type sympatholytic substances on muscle fatigue and contraction]. PMID- 4154133 TI - [Comparative kinetic study by fluorescence of monoamine depletion in the external area of the median eminence after inhibition of their synthesis by alpha-methyl paratyrosine in normal and adrenalectomized rats]. PMID- 4154134 TI - Studies of the metabolism of asialotransferrins: relationship between the carbohydrate composition of bovine, canine, and porcine asialotransferrins and their metabolic behavior in the rabbit. PMID- 4154135 TI - Occurrence of c-type cytochrome in Mycobacterium lepraemurium. PMID- 4154136 TI - Objective rhinomanometric clinical testing of an antihistamine (clemastine) combined with adrenergic substance (phenylpropanolamine). PMID- 4154138 TI - Glutamate dehydrogenase, glutamic acid decarboxylase, and GABA amino transferase in epileptic mouse cortex. PMID- 4154137 TI - Induction of rhythmic activity by harmaline. PMID- 4154139 TI - Medical treatment of Crohn's disease. PMID- 4154140 TI - Medical management of ulcerative colitis. PMID- 4154141 TI - Etiology of breast cancer. III. Opportunities for prevention. AB - Breast cancer, or its effects, may be preventable. Childbearing at an early age will confer some protection. Until there are other methods of primary prevention the physician must concentrate on secondary prevention, including screening. In presenting risk factors as criteria for screening we have attempted to make rational the use of screening technology. We should not easily accept screening for breast cancer as of proved value. Rather we must encourage clinical trials of various screening methods. In the meantime, while we engage in a moderate amount of screening we do so under the Scottish verdict of "not proven". PMID- 4154142 TI - Effect of cis-diamminedichloroplatinum (NSC-119875) on the allograft reaction in mice. PMID- 4154143 TI - Microsome-dependent binding of benzo(alpha)pyrene and aflatoxin B1 to DNA, and benzo(alpha)pyrene binding to aflatoxin-conjugated DNA. PMID- 4154144 TI - Short-term effects of free fatty acids on the regulation of fatty acid biosynthesis in Ehrlich ascites tumor cells. PMID- 4154145 TI - Structural studies of capsular polysaccharide of type XII Diplococcus pneumoniae. PMID- 4154146 TI - Ocelli of hydromedusae. PMID- 4154147 TI - Studies on the metabolism of D- and L-isomers of 3,4-dihydroxyphenylalanine (DOPA). VI. Metabolism of D-DOPA in rat kidney. PMID- 4154148 TI - [A case of Takayashu's disease]. PMID- 4154149 TI - Simulated multiday underwater habitation in hyperbaric helium-oxygen environment. PMID- 4154150 TI - Pharmacological characterization of adrenergic alpha and beta receptors mediating the vasomotor responses of cerebral arteries in vitro. PMID- 4154151 TI - The relationship of leucocyte adenyl cyclase activity and airways response to beta blockade and allergen challenge in extrinsic asthma. PMID- 4154152 TI - Congenital and acquired disturbances of histidine metabolism. PMID- 4154153 TI - Specific beta adrenergic blockade by practolol. PMID- 4154154 TI - Differential diagnosis in intersex conditions. PMID- 4154155 TI - Surgical construction of the male external genitalia. PMID- 4154156 TI - Nutrition and metabolism following thermal injury. PMID- 4154157 TI - Reduced serum somatomedin activity in patients with chronic liver disease. PMID- 4154158 TI - Editorial. Drug imprinting. PMID- 4154159 TI - Diet patterns and dental caries in third grade U. S. children. PMID- 4154160 TI - ECSI-a new index for evaluating caries progression. PMID- 4154161 TI - Assessment of gingival change using color photography. PMID- 4154162 TI - Dental injuries in Copenhagen schoolchildren, school years 1967-1972. PMID- 4154163 TI - Nitrogen excretion by the fresh water pulmonate snail, Lymnaea stagnalis jugularis Say. PMID- 4154164 TI - Free amino acids in fish brain: normal levels and changes upon exposure to high ammonia concentrations in vivo, and upon incubation of brain slices. PMID- 4154165 TI - Absorption of sugars in the gill of the Japanese oyster, Crassostrea gigas. PMID- 4154166 TI - Electrocardiographic characteristics of four anuran amphibia. PMID- 4154167 TI - Evidence for multiple inhibitory innervation of horseshoe crab muscles. PMID- 4154168 TI - The relation of blood hemoglobin concentration to body size in the toad Bufo boreas. PMID- 4154169 TI - Changes in serum osmotic and ionic concentration in landlocked Petromyzon marinus. PMID- 4154170 TI - Intracellular pH and electrolyte concentration in the uterine wall of the fowl in relation to shell formation and dietary minerals. PMID- 4154171 TI - Tissue and plasma electrolyte levels in the awake state during the year, in summer cold exposure and during arousal from hibernation in the hedgehog (Erinaceus europaeus). PMID- 4154172 TI - Variations of the level of the digestive enzymes during the intermolt cycle of Palaemon serratus: influence of the season and effect of the eyestalk ablation. PMID- 4154173 TI - Growth and development of temperature regulation in nestling cattle egrets. PMID- 4154174 TI - 42K efflux, EKG and tension in isolated perfused hearts of white-footed mice. PMID- 4154175 TI - Metabolic-temperature responses fo the copepod Euterpina acutifrons (Dana) from Brazil. PMID- 4154176 TI - Biochemical and cytochemical investigations of (Na+-K+)-ATPase in the crayfish kidney. PMID- 4154177 TI - Observations on K+-stimulated p-nitrophenylphosphatase in the lachrymal gland of Malaclemys terrapin, during adaptation to salt and fresh water. PMID- 4154178 TI - Variations in serum constituents of the blue crab, Callinectes sapidus: major cations. PMID- 4154179 TI - Evidence of a sclerotized collagen from the skeleton of a gorgonian coral. PMID- 4154180 TI - A pilot investigation of clinical effects of PM-33, a new anti-anxiety agent. PMID- 4154181 TI - Pilot open-label study on U-31,889 in anxious in-patients. PMID- 4154182 TI - Pharmacologic studies with triflubazam (ORF 8063): a new psychotherapeutic agent. PMID- 4154183 TI - Clozapine (Leponex) compared with chlorpromazine: a double-blind evaluation of pharmacological and clinical properties. PMID- 4154184 TI - The ballooning posterior leaflet syndrome: Minnesota Multiphasic Personality Inventory profiles in symptomatic and asymptomatic groups. PMID- 4154185 TI - Sex-related differences in drug metabolism. PMID- 4154186 TI - THe localization, metabolism and effects of drugs and toxicants in lung. PMID- 4154187 TI - [Therapy of terminal kidney failure through transplantation]. PMID- 4154188 TI - [Smallpox vaccination of patients over-aged for the 1st vaccination]. PMID- 4154189 TI - [Ulcerative colitis. Follow-up study of 160 patients observed for an average of 10 and one-half years (author's transl)]. PMID- 4154190 TI - [Chronic septic granulomatous disease in two brothers (author's transl)]. PMID- 4154191 TI - [Regional enteritis (Crohn's disease). A follow-up and comparative study of 182 patients (author's transl)]. PMID- 4154193 TI - [Therapy of severe bromcarbamide poisoning]. PMID- 4154194 TI - [The current state of caries research in the UdSSR]. PMID- 4154192 TI - [Gamma-glutamyl transpeptidase activities in 24-hour urine in various forms of kidney disease (author's transl)]. PMID- 4154195 TI - Metabolism of testosterone and 5alpha-dihydrotestosterone in vitro by the seminiferous tubules of the mature rat. PMID- 4154196 TI - Habitability in long-duration space missions. PMID- 4154197 TI - Distribution of 3H- and 14C-labelled potential neurotransmitters on a discontinuous density gradient after uptake into rat cerebral cortex slices. PMID- 4154198 TI - Effect of B6 deficiency on hepatoma 7794A growth rate: activities of tyrosine transaminase and serine dehydratase before and after induction by hydrocortisone. PMID- 4154199 TI - Cellular events in tolerance. IV. The effect of a graft-versus-host reaction and endotoxin on hapten- and carrier-specific tolerance. PMID- 4154200 TI - Induction of B cell tolerance to polysaccharides by exhaustive immunization and during immunosuppression with cyclophosphamide. PMID- 4154201 TI - Resistance to hydrocortisone conferred upon thymocytes by a thymic humoral factor. PMID- 4154202 TI - Phosphorylcholine-bearing components in homogenates of nematodes. PMID- 4154203 TI - Studies on the pharmacology of skeletal muscle in culture: specificity of receptors. PMID- 4154204 TI - The anticonvulsant action of the carbonic anhydrase inhibitor methazolamide: possible involvement of a noradrenergic mechanism. PMID- 4154205 TI - Paradoxical vagal tachycardia in ganglion-blocked anesthetized dogs. PMID- 4154206 TI - Centrally mediated bradycardia and hypotension induced by narcotic analgesics: dextromoramide and fentanyl. PMID- 4154207 TI - Possible involvement of central adrenaline neurons in vasomotor and respiratory control. Studies with clonidine and its interactions with piperoxane and yohimbine. PMID- 4154208 TI - On the synthesis of glutamine before and after fertilization of the sea urchin, Strongylocentrotus purpuratus. PMID- 4154209 TI - Uptake of certain possible neurotransmitters into retinal neurons of some mammals. PMID- 4154210 TI - Purification and properties of malic dehydrogenase from Trichomonas gallinae. PMID- 4154211 TI - A complex formation of the adrenal iron-sulfur protein (adrenodoxin) with cytochrome c and the decomposition of the iron-sulfur center. PMID- 4154212 TI - Photochemical activities of chloroplasts treated with diazonium-1,2,4-triazole. PMID- 4154213 TI - 8,9-Dihydro-8,9-dihydroxybenz(a)anthracene 10,11-oxide: a new type of polycyclic aromatic hydrocarbon metabolite. PMID- 4154214 TI - Purification and partial characterisation of 4-aminobutyrate 2-ketoglutarate transaminase from human brain. PMID- 4154215 TI - An energy independent interaction of ATP with the mitochondrial NADH dehydrogenase: competitive inhibition. PMID- 4154217 TI - NAD- and NADP-malic enzymes in spermatozoa of mammals and fish. PMID- 4154216 TI - Synthesis of ferritin in cultured hepatoma cells. PMID- 4154218 TI - A possible mechanism for the halothane-induced inhibition of mitochondrial respiration: binding of endogenous calcium to NADH dehydrogenase. PMID- 4154219 TI - Intermediary metabolism of the lung. PMID- 4154220 TI - [State of the rat coagulation and anticoagulation systems following administration of 6-hydroxydopamine]. PMID- 4154222 TI - Effect of psychoactive drugs on the motility of human spermatozoa. PMID- 4154221 TI - Lichen planus pigmentosus. PMID- 4154223 TI - The effect of some psychoactive drugs and metallic salts on the motility of rabbit spermatozoa. PMID- 4154224 TI - The influence of tissue polarity on nematocyte migration in Hydra attenuata. PMID- 4154225 TI - 1924-1974: hospitals through the looking glass. PMID- 4154226 TI - Death of patient urges better oxygen management. PMID- 4154227 TI - The strike weapon. PMID- 4154228 TI - Medical malpractice: plaintiff's counsel speaks. PMID- 4154229 TI - Innovations in health care systems research. PMID- 4154230 TI - Shared computer services: the Saskatchewan experience. PMID- 4154231 TI - Organizational environment and work satisfaction. PMID- 4154232 TI - A pioneer program for the emergency nurse. PMID- 4154233 TI - Menu costing: a curb for inflation. PMID- 4154234 TI - [Editorial: Dimensions marks 50 years]. PMID- 4154235 TI - Creating a future for nursing home services. PMID- 4154237 TI - [President's editorial: A milestone for the CHA]. PMID- 4154236 TI - Psychiatric needs of geriatric patients. PMID- 4154238 TI - The core committee: a management model for public health units. PMID- 4154239 TI - [Guest editorial: The diseases of choice are in our hands]. PMID- 4154240 TI - Regionalization and the small hospital: are trustees losing by default? PMID- 4154242 TI - The widening gap in labor relations goals. PMID- 4154241 TI - The hospital inquest: lessons in death. PMID- 4154243 TI - Hepatitis deaths provide more questions than answers. PMID- 4154244 TI - Renovation of physical medicine facilites: how to rehabilitate your rehab unit. PMID- 4154245 TI - Focus on productivity in food service. PMID- 4154246 TI - The perinatal intensive care unit: help for high risk infants. PMID- 4154247 TI - [Editorial: Hospitals must not be the scapegoat]. PMID- 4154249 TI - New handbook from B.C.: guideline standards for the OR nurse. PMID- 4154248 TI - An anesthetist's viewpoint: do pre-operative visits alleviate anxiety? PMID- 4154251 TI - Conflict of interest on hospital boards. PMID- 4154250 TI - The psychiatric team: a group approach to patient care. PMID- 4154252 TI - Evaluation by audit: a check system for nursing care. PMID- 4154253 TI - Ontario establishes hospital inquiry commission. PMID- 4154254 TI - The role of production in food service costs. PMID- 4154255 TI - Cost control in the hospital lab. PMID- 4154256 TI - The challenge of respiratory infections. PMID- 4154257 TI - Sterilization techniques for respiratory equipment. PMID- 4154258 TI - Preventive maintenance reduces x-ray equipment costs. PMID- 4154259 TI - Tobacco addiction: a cloud over hospitals. PMID- 4154260 TI - [Editorial: The constraints of morality]. PMID- 4154261 TI - Retention of medical records. PMID- 4154262 TI - Cyclic nucleotides and their role in gastrointestinal secretion. PMID- 4154263 TI - Marker discrimination and mutagen-induced alterations in pneumococcal transformation. AB - Nitrous acid-induced and hydroxylamine-induced chemical alterations in transforming DNA result in the loss of biological activity and in mutagenesis. The function responsible for the discrimination between high efficiency and low efficiency markers in pneumococcal transformation, and for the elimination of a substantial fraction of spontaneously occurring mutational events, does not appear to act on integrated DNA carrying these chemical alterations. The chemical modifications result in mutations that are evident among bacteria transformed with the treated DNA. Fusidic acid-resistant mutants isolated in this way have been shown to be predominantly of the low efficiency class. We have previously reported that most mutations of spontaneous origin occurring in this locus are of the high efficiency class, and have suggested that discrimination results from the elimination of specific classes of base pair mismatches that occur as intermediates in transformation. It would appear that the base pair mismatches most effectively eliminated in the discriminating strain of pneumococcus are those of the A:C and G:T type and that the immediate product of transformation with mutagenized DNA involves intermediates that are not recognized as A:C or G:T by the discrimination system. PMID- 4154264 TI - [Round-table conference. Part I. Epidemiologic diagnosis of chest diseases and its use in an integrated system of health service]. PMID- 4154266 TI - [Work ability of patients with pulmonary tuberculosis]. PMID- 4154265 TI - [Round-table conference. Part II. Value of criteria of evaluation of the epidemiologic situation in Poland]. PMID- 4154267 TI - [Methods of disability assessment of patients with diverse pulmonary diseases]. PMID- 4154268 TI - [Specific incorporation of the coenzyme analogue (3-(3 bromoacetylpyridinio)propyl)-adenosine pyrophosphate into the alcohol dehydrogenase from yeast (author's transl)]. PMID- 4154269 TI - [Peptide syntheses in the aqueous phase. Synthesis of some peptides and a mixture of erratic sequence peptide by the n-carboxyanhydride method (author's transl)]. PMID- 4154270 TI - [11Beta- and 17beta-hydroxysteroid dehydrogenase activity of rat liver: intracellular localization and sex differentiation]. PMID- 4154271 TI - [Effect of membrane lipids on the activity of NADH:semidehydroascorbic acid oxidoreductase (EC 1.6.5.4) of rat liver microsomes]. PMID- 4154272 TI - Action of thiamine on protein and nucleic acid metabolism, III. Transketolase activity of Lactobacillus viridescens during thiamine starvation. PMID- 4154273 TI - The formation of gamma-aminobutyrate in liver cell nuclei. PMID- 4154274 TI - [Sexually differentiated and sexually undifferentiated 3alpha- and 3beta hydroxysteroid dehydrogenase activities and their intracellular localization in rat liver]. PMID- 4154275 TI - [Inactivation of microsomal proteins by lysosomes (author's transl)]. PMID- 4154276 TI - Metabolism of 2-hydroxyoestrogen methyl ethers in the rat liver in vitro. PMID- 4154277 TI - [Subtilin, VI: the structure of subtilin (author's transl)]. PMID- 4154278 TI - [Kynurenine 3-hydroxylase in eyes of the honeybee Apis mellifica (author's transl)]. PMID- 4154279 TI - Editorial: Peptic ulcer: diet or drugs? PMID- 4154281 TI - Approved schools of nursing. PMID- 4154280 TI - Paramedical education. PMID- 4154282 TI - Illinois Government Agencies. PMID- 4154283 TI - Trauma Centers in Illinois. PMID- 4154284 TI - Poison control centers in Illinois. PMID- 4154285 TI - Licensed clinical laboratories. PMID- 4154286 TI - Approved renal dialysis facilities, centers and directors, Illinois Department of Public Health. Division of Disease Control. PMID- 4154287 TI - Artificial kidneys for acute poisoning cases. PMID- 4154288 TI - Medical legal information. PMID- 4154289 TI - Repeal of the Aurora brand interchange agreement. PMID- 4154290 TI - Surgical grand rounds. Stroke in a 19 year-old man. PMID- 4154291 TI - Computerized axial tomography with the EMI-scanner at Loyola University Medical Center. PMID- 4154292 TI - Ekg of the month. PMID- 4154293 TI - Transthoracic needle biopsy. PMID- 4154294 TI - Objective arterial venous examination in peripheral vascular disease. PMID- 4154295 TI - A clinical evaluation of simple renal cysts. PMID- 4154296 TI - Boutonniere deformity. PMID- 4154297 TI - Can essential hypertension be approached prophylactically? PMID- 4154298 TI - Surgical grand rounds: splenectomy. PMID- 4154299 TI - Perinatal health in Illinois. PMID- 4154300 TI - Editorials: Teenage psychological problems. PMID- 4154301 TI - Editorial: Sue me, sue me! PMID- 4154302 TI - Editorial: Doctors save lives by telephone. PMID- 4154303 TI - The suicide assessment team (SAT) in a general hospital. PMID- 4154304 TI - The education of an intern. PMID- 4154305 TI - Therapeutic efficacy of mebrophenhydramine in some pruritic dermatoses. PMID- 4154306 TI - Reduced nicotinamide adenine dinucleotide and reduced nicotinamide adenine dinucleotide phosphate diaphorase activity in human polymorphonuclear leukocytes. AB - Total reduced nicotinamide adenine dinucleotide (NADH) and reduced nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase activities were examined in human neutrophils. Approximately two-thirds of each enzyme activity was located in the granule fraction with the remainder in the soluble. The activities in a 27,000 x g supernatant from a sonic extract of human polymorphonuclear leukocytes were characterized. Both NADH and NADPH diaphorase were insensitive to cyanide and azide and showed greater activity at acid pH. K(m) values for nitroblue tetrazolium were not markedly different (33 muM with NADH and 12 muM with NADPH), but there was a 40-fold difference in K(m) for the reduced pyridine nucleotides (10 muM with NADH and 400 muM for NADPH). Since the intracellular concentration of both nucleotides is estimated to be about 50 muM, it is much more likely, from a kinetic argument, that the respiratory burst of phagocytosis is intiated by the oxidation of NADH rather than of NADPH. PMID- 4154307 TI - An assessment of oral disease among primary school children in Lebanon. I. Assessment of dental caries. PMID- 4154308 TI - Effects of anti-anaphylactic drugs upon passive cutaneous anaphylaxis mediated by graded doses of reaginic or non-reaginic antibodies in rats. PMID- 4154309 TI - Graft-versus-host reactions and activation of host antibody-forming cells induced by in vitro stimulated syngeneic lymphocytes. PMID- 4154310 TI - Stimulatory and inhibitory effects of graft-versus-host reactions on contact sensitivity in mice. PMID- 4154311 TI - Suppression of cellular immunity in rats and mice by maternal treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. PMID- 4154312 TI - Studies on the role of histamine and 5-hydroxytryptamine in immunity against the nematode Trichostrongylus colubriformis. III. Inhibition of worm expulsion from guinea pigs by treatment with reserpine. PMID- 4154313 TI - Hypotensive action of ICI66.082, a new beta-adrenergic blocking agent. PMID- 4154314 TI - Multidrug use: supplementary perspectives. PMID- 4154315 TI - The college opiate user. PMID- 4154316 TI - Personality traits and attitudes and their relationship to student drug using behavior. PMID- 4154317 TI - Patterns of drug abuse. PMID- 4154318 TI - Thymus-dependency of the immune response of mice to a primary infection with the nematode Trichuris muris. PMID- 4154319 TI - The peripheral and central role of the catecholamines in the mechanisms of anxiety. PMID- 4154321 TI - Caries experience in Arab and Jewish urban populations: a comparative study of schoolchildren in East and West Jerusalem. PMID- 4154320 TI - [Aspects of neuroleptic depot therapy with special consideration of clinical experiences with the preoral depot preparation Penfluridol (R 16 341-Jannsen)]. PMID- 4154322 TI - Transport of sugars and amino acids in bacteria. X. Sources of energy and energy coupling reactions of the active transport systems for isoleucine and proline in E. coli. PMID- 4154323 TI - Endo-beta-N-acetylglucosaminidases acting on the carbohydrate moieties of glycoproteins. The differential specificities of the enzymes from Streptomyces griseus and Diplococcus pneumoniae. PMID- 4154324 TI - Additional evidence for the liberation of substrate alpha-hydrogen prior to reduction of the coenzyme in D-amino acid oxidase reaction. PMID- 4154325 TI - Studies on receptor-mediated activation of adenylyl cyclases. IV. Characteristics of the adrenergic receptor coupled to myocardial adenylyl cyclase: stereospecificity for ligands and determination of apparent affinity constants for beta-blockers. PMID- 4154326 TI - Characteristics of ethanol and acetaldehyde oxidation on flavin and pyridine nucleotide fluorescence changes in perfused rat liver. PMID- 4154327 TI - Studies on the microsomal electron-transport system of anaerobically grown yeast. I. Intracellular localization and characterization. PMID- 4154330 TI - Stabilizing injured teeth with direct bonding. PMID- 4154328 TI - [Periarteritis nodosa and colonic perforation]. PMID- 4154329 TI - [Supra-aortic inflammatory arteriopathy in North African subjects. Limits of the so-called Takayasu's disease]. PMID- 4154331 TI - A controlled comparison of the effects of diphenylhydantoin and placebo on mood and psychomotor functioning in normal volunteers. PMID- 4154332 TI - Role of expectancy manipulation in systematic desensitization. PMID- 4154333 TI - Application of Faschingbauer's abbreviated MMPI to psychiatric inpatients. PMID- 4154334 TI - Systematic desensitization of test anxiety: a comparison of group and individual treatment. PMID- 4154335 TI - A 166-item written short form of the group MMPI: The FAM. PMID- 4154336 TI - Negro versus Caucasian psychological test performance revisited. PMID- 4154337 TI - Comparative validity of strategies and indices for differential diagnosis of depressive states from other psychiatric conditions using the MMPI. PMID- 4154338 TI - Transfer, behavioral improvement, and anxiety reduction in systematic desensitization. PMID- 4154339 TI - Personality differences between fee-paying and non-fee-paying patients seen for psychological testing. PMID- 4154340 TI - Comparison of the Minnesota multiphasic personality inventory and Mini-Mult with drug users. PMID- 4154341 TI - Strength mechanisms of dental solder joints. PMID- 4154343 TI - Watch your deductions! PMID- 4154342 TI - Effects of the control of plaque on the progression of dental caries: results after 19 months. PMID- 4154344 TI - A contribution to the study of immunological reactivity of the organism in agricultural workers. PMID- 4154345 TI - Clonal nature of the immune response to phosphorylcholine. III. Species-specific binding characteristics of rodent anti-phosphorylcholine antibodies. PMID- 4154346 TI - Influence of cyclophosphamide on the delayed hypersensitivity in the mouse after immunization with histocompatibility antigen. PMID- 4154347 TI - Regulatory role of T cells in IgG antibody formation and immune memory to type III Pneumococcal polysaccharide. PMID- 4154348 TI - Urticaria and arthralgias as manifestations of necrotizing angiitis (vasculitis). PMID- 4154349 TI - [Regulation of enzyme contents in animal bodies]. PMID- 4154350 TI - Drug therapy reviews: rational use of psychotropic drugs. III. Major tranquilizers. PMID- 4154351 TI - Scanning electron microscopy of mosquitoes. Part III. The egg surface structure of 5 species from Taiwan and 2 species from Indonesia. PMID- 4154352 TI - Studies on the neurogenic short-term control of adrenomedullary hormone synthesis. PMID- 4154353 TI - Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycemia. PMID- 4154354 TI - Development of an expression which relates the excitable state of the brain to the level of GAD activity and GABA content, with particular reference to the action of hydrazine and its derivatives. PMID- 4154355 TI - The effect of gamma-aminobutyric acid on brain mitochondrial ATP synthesis. PMID- 4154356 TI - Effect of neurotropic agents on total pyridoxal phosphate and on the activity of the decarboxylose of aromatic amino acids as well as of other pyridoxal phosphate dependent enzymes in rat brains. PMID- 4154358 TI - A study of selected catecholamine metabolizing enzymes: a comparison of depressive suicides and alcoholic suicides with controls. PMID- 4154357 TI - Properties of brain L-glutamate decarboxylase: inhibition studies. PMID- 4154359 TI - Uptake and release of possible false transmitter amino acids by rat brain tissue. PMID- 4154360 TI - Tyrosine hydroxylase and dopamine-beta-hydroxylase: distribution in the individual rat hypothalamic nuclei. PMID- 4154361 TI - Effects of enucleation and intra-ocular colchicine on the amino acids of frog optic tectum. PMID- 4154362 TI - [An electron microscopic study of skeletal musculature in terminal renal insufficiency]. PMID- 4154363 TI - Fibre hybrids in type groups. An investigation of human muscle biopsies. PMID- 4154364 TI - Congenital rod disease. Further evidence of innervational abnormalities as the basis for the clinicopathologic features. PMID- 4154366 TI - Leadership development at the clinical unit level. PMID- 4154365 TI - Plasma and cerebrospinal fluid levels of baclofen (Lioresal) at optimal therapeutic responses in spastic paresis. PMID- 4154367 TI - The meaning of work--1974. PMID- 4154368 TI - New intermediate hosts of the digenetic trematodes, Monorcheides cumingiae Martin (1938) and Neopechona pyriforme (Linton, 1900). PMID- 4154369 TI - The response of young diabetics to periodontal treatment. PMID- 4154370 TI - Do MMPI psychopathic deviancy scores reflect psychopathic deviancy or just deviancy? PMID- 4154371 TI - Clinical psychological testing in Tourette's syndrome. PMID- 4154372 TI - Decalin analogs of phenethylamines as inhibitors of amine uptake by rabbit platelets I: uptake and distribution of histamine. PMID- 4154373 TI - Antitumor activity and cardiac stimulatory effects of constituents of Anthopleura elegantissima. PMID- 4154374 TI - Drug release from hydroxypropyl cellulose-polyvinyl acetate films. PMID- 4154375 TI - Isolation and partial purification of hemolytic toxin from sea anemone, Stoichactis helianthus. PMID- 4154376 TI - Stimulus control of hexobarbital narcosis and metabolism in mice. PMID- 4154377 TI - Effect of dibutyryl cyclic adenosine monophosphate on 14C-dopamine biosynthesis in rat brain striatal slices. PMID- 4154378 TI - Beta receptor blocking and antiarrhythmic properties of tolamolol. PMID- 4154379 TI - Utilization of simulated patients to teach the routine pelvic examination. PMID- 4154380 TI - A guide to drug therapy in renal failure. PMID- 4154381 TI - General medical care identification and analysis of alternative approaches. PMID- 4154382 TI - [Study of bioelectrical activity of fibers of the intracardiac nervous system]. PMID- 4154383 TI - [Changes of depressor responses to bradykinin with preparations blocking kininase and adrenoreceptors]. PMID- 4154384 TI - [Oxygen metabolism in the limb tissues in patients with systemic vasculitis and certain collagenoses]. PMID- 4154385 TI - [Testicular torsion in children]. PMID- 4154386 TI - [Letter: Phagocytic activity of human blood neutrophils in conditions of normal activity and in a sealed chamber]. PMID- 4154387 TI - National nutrition policy conference: an end to apathy? PMID- 4154388 TI - [Impact on serum enzymes of viral hepatitis in a military environment]. PMID- 4154389 TI - A television fluorometer for monitoring oxidative metabolism in intact tissue. PMID- 4154391 TI - Otolaryngology in Australia through a retrospectoscope. PMID- 4154390 TI - A multicentre trial of perhexiline maleate, beta-blocker and placebo in angina pectoris. PMID- 4154392 TI - Editorial: Pneumococcal typing and sensitivity. PMID- 4154393 TI - Type distribution and antibiotic sensitivity of Diplococcus pneumoniae. A five year study in Sydney. PMID- 4154394 TI - Editorial: Epidemic polyarthritis. PMID- 4154395 TI - Cephradine--a new oral cephalosporin antibiotic. PMID- 4154396 TI - [On therapy of post-vaccinal encephalitis]. PMID- 4154397 TI - Catecholamine synthetic enzymes of spontaneously hypertensive rats and microbial hypotensive products. PMID- 4154398 TI - Enzymology at sub-zero temperatures. PMID- 4154399 TI - Mechanisms and physiological roles of fatty acid chain elongation in microsomes and mitochondria. PMID- 4154400 TI - The development of our current concepts of biological oxidations. PMID- 4154401 TI - The formation and kinetics of reactive drug metabolites in mammals. PMID- 4154402 TI - Mutagenic activation of dimethylnitrosamine and diethyl-nitrosamine in the host mediated assay and the microsomal system. PMID- 4154404 TI - Alternate host for mosquito parasite Coelomomyces. PMID- 4154403 TI - Isolation of photoreceptor and conventional nerve terminals by subcellular fractionation of rabbit retina. PMID- 4154405 TI - Light-evoked release of glycine from the retina. PMID- 4154406 TI - Acetylcholine as an excitatory neuromuscular transmitter in the stomatogastric system of the lobster. PMID- 4154407 TI - Glutamate metabolism in the frog retina. PMID- 4154408 TI - Temperature-dependent interconversion of histamine H1 and H2 receptors in guinea pig ileum. PMID- 4154409 TI - How selective is high affinity uptake of GABA into inhibitory nerve terminals? PMID- 4154410 TI - In vitro enhancement of hepatic microsomal biphenyl 2-hydroxylation by carcinogens. PMID- 4154411 TI - Syndrome of ankylosis, facial anomalies, and pulmonary hypoplasia. PMID- 4154412 TI - The coenzyme-binding domains of glutamate dehydrogenases. PMID- 4154414 TI - Beta-adrenolytic, antiarrhythmic and local anaesthetic effects of phenylephrine. PMID- 4154413 TI - Effect of histamine, pentagastrin and theophylline on the production of cyclic AMP in isolated gastric tissue of the guinea pig. PMID- 4154415 TI - [Frequency of use and caries inhibiting effect of F-tablets in school children]. PMID- 4154416 TI - [Fluoridation of drinking water. V. Comparison of dental health in 17 and 18 year old adolescents in Culemborg and Tiel, Netherlands]. PMID- 4154417 TI - [Dental health of 5 to 11-year-old children in north east Friesland (the Netherlands)]. PMID- 4154418 TI - [Characteristics of NADP-dependent isocitrate dehydrogenase in rat brain]. PMID- 4154419 TI - Modification of the receptor component of adenylate cyclase in the rat brain by phenothiazine derivatives. PMID- 4154420 TI - Dissociation between amino-oxyacetic acid-induced depression of spinal reflexes and the rise in cord GABA levels. PMID- 4154421 TI - [High-altitude hypoxia as a hypothetical method of treatment of angina pectoris]. PMID- 4154422 TI - Work, society, and health. Identifying a worldwide resource for nursing education. PMID- 4154423 TI - Work, society, and health. Introductory remarks: the Distributive Nursing Project. PMID- 4154424 TI - [On the relation among OFI index and the indices of oral hygiene, periodontal disease and caries in adults. Especially on the difference between male and female (author's transl)]. PMID- 4154425 TI - [Round-table conference on the organization of medical care and research in cases of injuries of the central nervous system]. PMID- 4154426 TI - Chronic diarrhea in childhood: a new look at an old problem. PMID- 4154427 TI - Persistent systemic hypertension in infants and children. PMID- 4154428 TI - [Pulmonary problems of childhood at the All-Union Congress of Pediatricians]. PMID- 4154429 TI - [Problems of childhood infections at the All-Union Congress of Pediatricians]. PMID- 4154430 TI - Vascular nephropathies with acute renal failure. PMID- 4154431 TI - Arteritis with impaired renal function. PMID- 4154432 TI - Blood coagulation and renal disease. PMID- 4154433 TI - [Non-respiratory functions of the adult lung. 2- Metabolic functions]. PMID- 4154434 TI - [Letter: Bupranolol, a beta-blocker acting on insulin secretion in obesity]. PMID- 4154435 TI - [Gamma glutamyl transpeptidase (GGTP) in chronic hepatitis]. PMID- 4154436 TI - [Treatment of arrhythmia with adrenergic beta receptor blockaders]. PMID- 4154437 TI - Dimorphism of ureides. alpha-Bromisovalerylurea (bromisoval) and alpha bromdiaethylacetylcarbamide (carbromal). PMID- 4154438 TI - Prevalence and management of hypertension in a general population sample of Swedish men. PMID- 4154439 TI - Cyclic AMP-mediated induction of the cyclic AMP phosphodiesterase of C-6 glioma cells. AB - Long-term regulation of the cyclic nucleotide phosphodiesterase of the C-6 rat glioma cell line has been studied. Both the low K(m) and high K(m) activities can be induced by elevation of intracellular cyclic AMP levels following either dibutyryl cyclic AMP or norepinephrine treatment of the cells. The enzymes are maximally induced by 3-4 hr. The presence of either cycloheximide or actinomycin D prevents induction by either dibutyryl cyclic AMP or norepinephrine. Evidence is presented that the norepinephrine effect is mediated by the beta-catecholamine receptor. The increased phosphodiesterase activity causes a partial refractoriness to a second challenge with norepinephrine, which can be overcome by blockade of the induction with cycloheximide. The results suggest that just as short-term regulation of cyclic AMP levels occurs via changes in the rates of synthesis or degradation, long-term alterations of the system may also involve either the adenylate cyclase or the phosphodiesterase. PMID- 4154440 TI - Conformational changes induced in dihydrofolate reductase by folates, pyridine nucleotide coenzymes, and methotrexate. AB - Dihydrofolate reductase (EC 1.5.1.3; 5,6,7,8-tetrahydrofolate:NADP(+) oxidoreductase) from antifolate-resistant Lactobacillus casei has been isolated in pure form and examined in solution by high resolution proton magnetic resonance spectroscopy. The 220 MHz proton magnetic resonance spectrum of this small enzyme (about 15,000 daltons) consists of several distinct resonance peaks that provide a sensitive nonperturbing probe of its conformational state. Comparison of catalytically active enzyme with preparations denatured in 6 M urea demonstrates dramatically the overall contribution of secondary and tertiary structure to its proton magnetic resonance spectra. More subtle differences existing among several catalytically active enzyme forms may also be readily differentiated by proton magnetic resonance spectroscopy, e.g., the spectra of the ligand-free enzyme and forms containing stoichiometric amounts of tightly bound folate and dihydrofolate, each obtained separately by affinity chromatography, are easily identified. Addition of ligands to these spectroscopically distinct forms may induce changes in their proton magnetic resonance spectra. For example, addition of equimolar dihydrofolate to the apoenzyme converts its relatively featureless aromatic proton magnetic resonance spectrum to one indistinguishable from that of the original enzyme-dihydrofolate binary complex obtained chromatographically. Interaction of the pyridine nucleotide coenzymes NADP(+) or NADPH or of the antifolate Methotrexate with apoenzyme induces additional distinct spectral changes. Enzyme-NADPH and enzyme Methotrexate binary complexes, which have different aromatic region proton magnetic resonance spectra, are converted to ternary complexes having quite similar spectra by addition of Methotrexate and NADPH, respectively, thus suggesting that an ordered addition of ligands is not required. PMID- 4154441 TI - Enhancement of tumor growth by graft-versus-host reaction. AB - A graft-versus-host reaction was induced in (BALB/c x C5 7BL/6)F(1) mice by intravenous injection of BALB/c spleen cells. Six days later, the mice received subcutaneous grafts of a chemically induced BALB/c sarcoma. The growth of the tumor grafts was accelerated. PMID- 4154442 TI - Stimulation of the hydrolytic activity and decrease of the transpeptidase activity of gamma-glutamyl transpeptidase by maleate; identity of a rat kidney maleate-stimulated glutaminase and gamma-glutamyl transpeptidase. AB - gamma-Glutamyl transpeptidase catalyzes transfer of the gamma-glutamyl moiety of glutathione (and other gamma-glutamyl compounds) to amino acid and peptide acceptors; this reaction probably involves (a) formation of a gamma-glutamyl enzyme and (b) reaction of the gamma-glutamyl-enzyme with an acceptor. Maleate decreases the latter reaction and markedly increases hydrolysis of the gamma glutamyl donor, apparently by affecting the enzyme so as to facilitate reaction of the gammaglutamyl enzyme with water. Transpeptidase catalyzes gamma-glutamyl hydroxamate formation from many gamma-glutamyl compounds and hydroxylamine; this reaction is stimulated 4- to 5-fold by maleate. Glutamine, a poor substrate for transpeptidation as compared to glutathione, is slowly hydrolyzed and converted to gamma-glutamyl-glutamine by the transpeptidase; in the presence of maleate, hydrolysis of glutamine is markedly (>10-fold) increased, as is also its conversion to gamma-glutamyl hydroxamate in the presence of hydroxylamine. The findings suggest that the previously described "maleate-stimulated phosphate independent glutaminase" is a catalytic function of gamma-glutamyl transpeptidase. Transpeptidase-catalyzed glutaminase activity may play a role in renal ammoniagenesis. The ability of maleate to decrease transpeptidation of gamma-glutamyl compounds (and to increase their hydrolysis to glutamate), when considered in the light of earlier findings that treatment of animals with maleate produces aminoaciduria, is consistent with function of transpeptidase and the gamma-glutamyl cycle in amino-acid transport. PMID- 4154444 TI - Synaptic connections made by horizontal cells within the outer plexiform layer of the retina of the cat and the rabbit. PMID- 4154443 TI - Intracellular restraint: a new basis for the limitation in response to oxidative stress in human erythrocytes containing low-activity variants of glucose-6 phosphate dehydrogenase. AB - Several mechanisms recently proposed for regulation of the hexose monophosphate shunt require the concentration of NADP to be low or that of NADPH to be high. The present study indicates that the first enzyme of the hexose monophosphate shunt of human erythrocytes is under severe restraint even when these conditions do not exist. In human erythrocytes containing low-activity variants of this enzyme, glucose-6-phosphate dehydrogenase (D-glucose-6-phosphate:NADP(+) 1 oxidoreductase; EC 1.1.1.49), measurements of the rate of oxidation of C-1 labeled glucose show that the enzyme is operating at a rate much closer to its maximum than in normal cells. This requires that the ratio of inhibitory NADPH to NADP be much lower in the variant cells than in normal cells. A small increase in oxidative rate, induced by naphthol, then causes a disappearance in reduced glutathione in the variant cells, presumably because a significant further decrease in NADPH occurs in these cells, whereas the same oxidative stress in normal cells would not lower the NADPH level appreciably. A low NADPH/NADP ratio in unstressed cells deficient in glucose-6-phosphate dehydrogenase is confirmed by direct measurement. The maximum activity of the variant enzyme in the cell, as measured with methylene blue to keep most of the NADP in the oxidized form, is only about 1/60 of that found in hemolysates, thus accounting for the failure to compensate for a relatively small oxidative stress in vivo in spite of an apparent sufficiency of enzyme. The reason for the limitation on maximum intracellular activity is unknown. A similar limitation is seen with normal cells incubated with methylene blue, where the maximum intracellular rate is also only about 1/60 of that found in hemolysates. PMID- 4154445 TI - Studies on bile secretion with the aid of the isolated perfused rat liver. I. Inhibitory action of sporidesmin and icterogenin. PMID- 4154446 TI - Nutrition of algal-invertebrate symbiosis. I. Utilization of soluble organic nutrients by symbiont-free hosts. PMID- 4154447 TI - The sphincter pupillae of the guinea-pig: structure of muscle cells, intercellular relations and density of innervation. PMID- 4154448 TI - Orchidectomy and the immune response. III. The effect of orchidectomy on tumour induction and transplantation in mice. PMID- 4154449 TI - Mechanisms and evolutionary origins of variable X-chromosome activity in mammals. PMID- 4154450 TI - Evidence that ATP is hydrolysed in a one-step reaction of the sodium pump. PMID- 4154451 TI - Rates of dispersal of Drosophila pseudoobscura and its relatives. PMID- 4154452 TI - Hormonal modulation of circadian neural activity in Carcinus maenas (L.). PMID- 4154453 TI - On the structure and innervation of the muscle bands of Doliolum (Tunicata: Cyclomyaria). PMID- 4154454 TI - Suppression of contact sensitivity by T cells in the mouse. I. Demonstration that suppressor cells act on the effector stage of contact sensitivity; and their induction following in vitro exposure to antigen. PMID- 4154455 TI - Tapeta lucida in the eyes of goatsuckers (Caprimulgidae). PMID- 4154456 TI - The internal structure of the chromaffin granule. PMID- 4154457 TI - Electrogenic sodium pump in mouse liver parenchymal cells. PMID- 4154458 TI - Alopecia areata, vitiligo, scleroderma and ulcerative colitis. PMID- 4154459 TI - Further observations on the spasmogenic activity of caerulein on the rat pylorus. PMID- 4154461 TI - On the functional morphology of the family Verticortiidae (Bivalvia) with descriptions of new species from the abyssal Atlantic. PMID- 4154460 TI - On the reversal by (plus) and (minus)-propranolol of irreversible alpha adrenoceptor blockade in rabbit aorta. PMID- 4154462 TI - Modes of activation of motoneurons controlling ventilatory movements of the locust abdomen. PMID- 4154463 TI - The organization of inputs to motoneurons of the locust metathoracic leg. PMID- 4154464 TI - Synapses upon motoneurons of locusts during retrograde degeneration. PMID- 4154465 TI - Implantation, foetal membranes and early placentation of the African elephant, Loxodonta africana. PMID- 4154466 TI - [Anaphylactic shock following an injection of trombovar]. PMID- 4154467 TI - Psychopharmacological evidence for increase in receptor sensitivity following chronic morphine treatment. PMID- 4154468 TI - Free fatty acid mobilization during suggestion of exercise and stress using hypnosis and sodium amytal. PMID- 4154469 TI - Differences in the modulation of cardiac activity between psychopaths and normal controls. PMID- 4154470 TI - Proceedings: Dose effects of stimulants in hyperkinetic children. PMID- 4154471 TI - Proceedings: The nature of the interaction between melanin and drugs. PMID- 4154472 TI - Proceedings: Drugs, neurotransmitters, and psychosis. PMID- 4154473 TI - Proceedings: Drug toxicity as related to ocular melanin. PMID- 4154474 TI - Proceedings: Phenothiazine drugs and melanin synthesis. PMID- 4154475 TI - Proceedings: Metabolic adaptation to antidepressant drugs--a neurochemical paradox. PMID- 4154476 TI - Proceedings: Neuroendocrine transducers: brain monoamines and the control of hypothalamo-pituitary function. PMID- 4154477 TI - Proceedings: Putative neurotransmitters involved in discharging gonadotropin releasing factors and the action of these neurohormones on the central nervous system. PMID- 4154478 TI - Identifying future alcoholics with MMPI alcoholism scales. PMID- 4154479 TI - Competitive radioprotection and radiosensitization in chemical systems. PMID- 4154480 TI - [Relation between the electrical activity and free amino acid level of the brain of white rats after total-body x-irradiation]. PMID- 4154481 TI - [Tracers for synaptic vesicle (author's transl)]. PMID- 4154482 TI - [Enzymatic methods for the identification of a transmitter substance in a specific brain nucleus (author's transl)]. PMID- 4154483 TI - [3d European narcodontologic days. Opening address]. PMID- 4154484 TI - [Histometric studies on unilateral and bilateral cryptorchidic and scrotal testes (author's transl)]. PMID- 4154485 TI - [Editorial: Delegation of medical actions]. PMID- 4154486 TI - [The respiratory analeptic action of isoprenaline and orciprenaline (author's transl)]. PMID- 4154487 TI - Production of glutamine synthetase by Proteus mirabilis in short time periods. PMID- 4154488 TI - [Binary complexes of lactic dehydrogenase with NAD or NADH (author's transl)]. PMID- 4154489 TI - The experimental imperative: laboratory analyses of aggressive behaviors. PMID- 4154490 TI - The effect of mesuprine HC1 on selected smooth muscles. PMID- 4154491 TI - Microsomal (muS) chemiluminescence (CL) induced by NADPH and its relation to aryl hydroxylations. PMID- 4154492 TI - Regulation of thiols in the brain. 3. Glucose metabolism in the cytoplasmic fraction of rat brain during stimulation of the hexose monophosphate shunt in vitro. PMID- 4154493 TI - [Effects of Clonazepam on interaction phenomena of experimental bilateral rhinencephalic epileptic activity]. PMID- 4154494 TI - [Experimental study of the anti-epileptic action of Clonazepam on "acute" rhinencephalic epilepsy in rabbits]. PMID- 4154495 TI - Interaction of cholinergic function with mg2 plus-na plus-k plus-dependent ATP ase system of cells in the human fundic gastric mucosa. PMID- 4154496 TI - [Caries-inhibiting properties of Na2FPO3 toothpaste after 5-year evaluation studies]. PMID- 4154497 TI - Beta-adrenergic receptor: stereospecific interaction of iodinated beta-blocking agent with high affinity site. AB - An iodine-labeled beta-adrenergic inhibitor ((125)l-hydroxybenzylpindolol) binds specifically to a site on turkey erythrocyte membranes. A series of beta adrenergic agonists and inhibitors compete for this binding site, with apparent affinities paralleling biological effectiveness as activators or inhibitors of catecholaminestimulated adenylate cyclase. The activity of d-(+) agonists or inhibitors was 1 percent (or less) than that of the corresponding l-(-) isomers in competing for binding of the iodinated blocker as well as in affecting catecholamine-stimulated adenylate cyclase. 1-(-)-Norepinephrine was about one tenth as active as l-(-)-isoproterenol in competing for the beta-blocking agent site. The stereospecificity of the interaction with the iodinated beta-blocking agent and the correspondence between affinity for site and biological potency of analogs suggested that this interaction is involved in function of the beta adrenergic receptor. PMID- 4154498 TI - The transplantation milieu, St. Luke's Episcopal Hospital, 1968-1969. PMID- 4154499 TI - The living, genetically unrelated, kidney donor. PMID- 4154500 TI - Psychiatric side effects of nonpsychiatric drugs. PMID- 4154501 TI - Depressions following reserpine: a reevaluation. PMID- 4154502 TI - Uses and toxicity of belladonna alkaloids and synthetic anticholinergics. PMID- 4154503 TI - Population changes in antigen-binding and antibody-secreting cells in the course of the immune response. PMID- 4154504 TI - Genetic fine structure of the H-2 gene complex. PMID- 4154505 TI - Purulent pericarditis in South Vietnam: report of 16 cases. PMID- 4154506 TI - Rapid identification of pills, capsules, and other forms of drugs. PMID- 4154507 TI - Japanese encephalitis vectors: isolation of virus from culicine mosquitoes in the Saigon area. PMID- 4154508 TI - Lankesteria, a gregarine protozoan, previously unreported in mosquitoes of Malaysia. PMID- 4154509 TI - Does regenerative capacity decrease with age? PMID- 4154511 TI - Pharmacology and toxicology of metiamide, a histamine H2-receptor antagonist. PMID- 4154510 TI - Influence of pharmacological agents on the growth of processes of spinal ganglion nerve cells in culture. PMID- 4154512 TI - Acquired immunologic deficiencies after trauma and surgical procedures. PMID- 4154513 TI - [Effect of adrenergic drugs on gastric secretion in relation to its initial level]. PMID- 4154514 TI - [Liver circulation in patients with pancreatitis in the dynamics of complex treatment using ultrasound]. PMID- 4154515 TI - [Some peculiarities of the clinical aspects and therapy of acute pneumonia without leukocytosis]. PMID- 4154516 TI - [Complex etiopathogenic therapy of decompensatory cor pulmonale (aid to the practicing physician)]. PMID- 4154517 TI - [Systemic vasculitis]. PMID- 4154518 TI - [Changes of the indicators of central hemodynamics in patients with hypertensive disease during treatment with obsidan]. PMID- 4154519 TI - [Treatment of arterial hypertension using beta-blockaders]. PMID- 4154520 TI - [Progress in inflammatory diseases of the colon (author's transl)]. PMID- 4154521 TI - [Caries incidence in Cuban children in areas where brown or refined white sugar is predominantly consumed]. PMID- 4154522 TI - Fetal thymus glands obtained from prostaglandin-induced abortions. Cellular immune function in vitro and evidence of in vivo thymocyte activity following transplantation. PMID- 4154523 TI - Cystometry. PMID- 4154524 TI - Cryptorchidism. A pediatric review. PMID- 4154525 TI - Management of testicular tumors in children. PMID- 4154526 TI - [Mental condition of the patients before and after hearing-improving operations]. PMID- 4154527 TI - Biochemical and biophysical properties of two strains of mosquito iridescent virus. PMID- 4154528 TI - [Treatment of ulcerative hemorrhaging colitis with immunosuppressive drugs]. PMID- 4154529 TI - [Anti-allergic and immunosuppressive treatment of rheumatism and rheumatoid arthritis]. PMID- 4154530 TI - [Immunologic problems in massive blood transfusions]. PMID- 4154531 TI - [Serum glutamyl transpeptidase in patients with endemic nephritis]. PMID- 4154532 TI - [The content of nicotinamide coenzymes NAD and NADH, and the adenyl system in diabetics]. PMID- 4154533 TI - [The influence of beta receptor blockade on the incidence of postoperative cardiovascular complications (author's transl)]. PMID- 4154534 TI - [The influence of heparin on the activity of plasma enzymes in patients on intermittent haemodialysis (author'r transl)]. PMID- 4154535 TI - [The problems of early diagnosis of liver metastases: an evaluation of the individual diagnostic procedures (author's transl)]. PMID- 4154536 TI - [Therapy of angina pectoris]. PMID- 4154537 TI - [Heparin treatment in peracute glomerulonephritis]. PMID- 4154538 TI - The enzymic formation of methylenedioxyphenyl derivative exhibiting an isocyanide like spectrum with reduced cytochrome P-450 in hepatic microsomes. PMID- 4154539 TI - Metabolic interconversions and binding of imipramine, imipramine-N-oxide, and desmethylimipramine in rat liver slices. PMID- 4154540 TI - Metabolism of prolintane in rats and the effect of prolintane metabolites on general activities in mice. PMID- 4154541 TI - Editorial: An open letter to a committee searching for a chairman of a department of medicine. PMID- 4154542 TI - An improved coupled test procedure for glutathione peroxidase (EC 1-11-1-9-) in blood. PMID- 4154543 TI - [Disc-electrophoresis of multiple forms of arylamidase. Studies on human arylamidases, I (author's transl)]. PMID- 4154544 TI - The application of the serum gamma-glutamyl transpeptidase and the 5' nucleotidase assay in cancer patients: a comparative study. PMID- 4154546 TI - The effect of temperature on enzyme activity and on the affinity of enzymes to their substrates. PMID- 4154545 TI - [A simple method for the determination of enzyme activities in turbid plasma of patients with hyperlipoproteinemia (author's transl)]. PMID- 4154547 TI - [Sensitive determination of bromocarbamides in body fluids using thin layer chromatography]. PMID- 4154548 TI - [Measures and units in clinical chemistry. The international recommendations (IFCC, ISO, IUPAC). Achieved by work of a commission of the Swiss, Austrian, and German Clinical Chemistry Societies]. PMID- 4154549 TI - [The gamma-glutamyltransferase (author's transl)]. PMID- 4154550 TI - Autochthonous grafts of spontaneous mammary tumors implanted together with allogeneic tissues. PMID- 4154551 TI - [Proceedings: Microcirculation and ventricular-wall function in the normal and partially ischemia-damaged myocardium under pharmacologic influence in animal experiment]. PMID- 4154552 TI - [Pathogenesis of essential hypertension (the possible primary deficiency in the humoral depressor mechanism) (an article for discussion)]. PMID- 4154553 TI - [Complex treatment of chronic ulcers and deep pyoderma]. PMID- 4154554 TI - [Periarteriitis nodosa in the course of a primary chronic polyarthritis]. PMID- 4154555 TI - [Problems of children's dental care in the USA]. PMID- 4154556 TI - [Role of the scientific medical societies in the improvement of qualifications of the practicing physicians]. PMID- 4154557 TI - [Role of the conventions of the local government physicians of the Kostroma District in the development of public health (on the centenary of the 1st District Convention of local government physicians)]. PMID- 4154558 TI - [Oncological service during 50 years of the Kirghiz Republic and the Kirghiz Communist Party]. PMID- 4154560 TI - [Achievements of the rural public health of Kirghizia during the past 50 years (2d report, 1941-1973)]. PMID- 4154561 TI - [Dermatological-venereological service in Kirghizia during the past 50 years]. PMID- 4154562 TI - [Development of endocrinology in Kirghizia]. PMID- 4154559 TI - [Results of the scientific activity of the Kirghiz Scientific-Research Institute of Health Resorts and Physiotherapy]. PMID- 4154563 TI - [Public health in Kirghizia during the past 50 years]. PMID- 4154564 TI - [Study of electrical conductivity of air and its hygienic importance]. PMID- 4154565 TI - [Combined foci of arboviruses on the territory of Ala-Bukinsk region of the Osha District]. PMID- 4154566 TI - [Indicators of red blood and erythrocyte count in healthy young children under different altitude conditions in Kirghizia]. PMID- 4154567 TI - [Traumatic arterio-venous fistulas]. PMID- 4154568 TI - [Acute cholecystitis and its surgical treatment]. PMID- 4154569 TI - [Emergency aid in the injuries of the eyeball and its appendages]. PMID- 4154570 TI - [Australia antigen carriers among the population of the Osha district]. PMID- 4154571 TI - [Prevention of pathological effect of occupational hazards in the grain processing industry]. PMID- 4154572 TI - [Certain principles of vascularization of the suture area and anastomoses of the organs during surgery (experimental studies)]. PMID- 4154573 TI - [Certain results of scientific studies concerning maternal and child welfare]. PMID- 4154574 TI - [Response to air pollution in schoolchildren. Results and experience from several years of study]. PMID- 4154576 TI - [Drinking water fluoridation animal studies]. PMID- 4154575 TI - [Retention and elimination of lead fluoride following experimental administration to animals by the oral route]. PMID- 4154577 TI - [Analysis of pulmonary function in experimental animals during inhalation of zinc oxide dust]. PMID- 4154579 TI - [100 years of Mycobacterium leprae]. PMID- 4154578 TI - [Rhodanide as a catalyst of nitrosamine synthesis in vivo]. PMID- 4154580 TI - The determinants of microbial pathogenicity. PMID- 4154581 TI - [Factors of pathogenicity in gram-positive and gram-negative bacteria]. PMID- 4154582 TI - [The present situation of drinking water supply in the Federal Republic of Germany]. PMID- 4154583 TI - [Factors of pathogenicity in beta-hemolysing streptococci]. PMID- 4154584 TI - [Humoral mechanisms of endogenous defense against infections]. PMID- 4154585 TI - [Cellular antibacterial immunity]. PMID- 4154586 TI - A role for cell-mediated immunity in the pathogenesis of periodontal disease. PMID- 4154587 TI - [Immunological defense capacity in persons of advanced age]. PMID- 4154588 TI - [Effects of the positive directional steady electrostatic field on the degree of immunization]. PMID- 4154589 TI - [Determination of the cellular immune response with the aid of a bacterial indicator system]. PMID- 4154590 TI - [Studies of the "clumping factor" of staphylococci]. PMID- 4154591 TI - [Leukocidin from bovine Staphylococcus aureus]. PMID- 4154592 TI - [The specific and nonspecific defenses against infection in the bovine mammary gland]. PMID- 4154593 TI - [Drinking water from surface water sources: technical problems]. PMID- 4154594 TI - [Experimental protective immunization of mice against S. typhimurium infection by Salmonella R mutants]. PMID- 4154595 TI - [Salmonella-E. coli hybrid: characterization and immunological efficacy]. PMID- 4154596 TI - [Analysis of the immunogenic effect of liquid and freeze-dried smallpox vaccine (as demonstrated in more than 20,000 persons vaccinated three times)]. PMID- 4154597 TI - [General immunogenesis after oral uptake of killed Pertussis bacteria]. PMID- 4154599 TI - [Demonstration of toxoplasma antibody with the aid of immunofluorescence]. PMID- 4154598 TI - [Serological differentiation of mucosal and systemic candidiasis]. PMID- 4154600 TI - [Models of urinary infection]. PMID- 4154601 TI - [Hygiene as an environmental science]. PMID- 4154602 TI - [Immunological defense and virulence of the agent in experimental chronic infection]. PMID- 4154603 TI - [Humoral and cellular factors of immunological defense against infection exemplified by estrogen-facilitated pyelonephritis in rats]. PMID- 4154604 TI - [Disturbance of the local vesicular defense as a cause of cystitis manifestation]. PMID- 4154605 TI - [Pathogenicity of L forms and spheroblasts in chronic urinary tract infection during childhood]. PMID- 4154606 TI - [Presence and identification of inorganic pollutants in water]. PMID- 4154607 TI - [Comparative typing of Herpes simplex virus strains by serological and biological methods]. PMID- 4154608 TI - [A biochemical differentiation of thymidine kinase induced by type 1 and 2 herpesvirus]. PMID- 4154609 TI - [DNA synthesis in isolated nuclei and mitochondria from HeLa cells infected by Herpes simplex virus]. PMID- 4154610 TI - [Formation of antibody to nucleocapsid and envelope of Herpes simplex virus hominis]. PMID- 4154611 TI - [Type 2 Herpes simplex virus and cervical carcinoma]. PMID- 4154613 TI - [G and M immunoglobulins during acute hepatitis. Quantitative and qualitative studies]. PMID- 4154612 TI - [Presence of hepatitis B antibody in operators of a plasma fractionating plant, hospital staff, patients, and blood donors]. PMID- 4154614 TI - [Presence of Australia antigen, histocompatibility (HL-A) antigens, and autolymphocytotoxins (CoCoCy) during different forms of hepatitis and cirrhosis]. PMID- 4154615 TI - [Trial of a hemagglutination test for hepatitis B antigen]. PMID- 4154616 TI - [Standardization of the sepharose radioimmunoassay to identify hepatitis B antigen in major volumes of water]. PMID- 4154617 TI - [Virus-inactivating effectiveness of different methods of effluent treatment]. PMID- 4154618 TI - [Use of the IgM fraction from patients' sera in general virus serology for diagnostic purposes]. PMID- 4154619 TI - [Possible labelling of antigens in virus-infected cell cultures under the transmission and scanning type electron microscope]. PMID- 4154620 TI - [Physico-chemical changes of the cell surface of Ehrlich ascites tumour cells following infection with oncolytic influenza virus]. PMID- 4154621 TI - [Influence of vesicular stomatitis virus upon growth and immunogenicity of a transplantable murine tumour]. PMID- 4154622 TI - [Significance of the envelope in CMV infections]. PMID- 4154623 TI - [Demonstration of antibody-synthesizing cells in mice and swine by means of local hemolysis in gel following immunization with foot-and-mouth disease virus and vaccine]. PMID- 4154624 TI - [LCM virus-specific antigens]. PMID- 4154625 TI - [New surface antigens on LCM virus-infected cells]. PMID- 4154626 TI - [Immunological phenomena in LCM virus-infected mice]. PMID- 4154627 TI - [Murine lymphocytic choriomeningitis: pathology of the lymphatic tissue]. PMID- 4154628 TI - [Alterations of drinking water quality due to bacterial re-contamination]. PMID- 4154629 TI - [Terms of reference and structure of the International Committee on Systematic Bacteriology]. PMID- 4154630 TI - [A report on the essential changes envisaged for the new edition of bacterial nomenclature rules]. PMID- 4154631 TI - [Cold sterilization: trials with formalin vapors]. PMID- 4154632 TI - [Biological indicators for the control of autoclave function: some theoretical aspects and practical experience in their development and application]. PMID- 4154633 TI - [Presence and importance of technically nondesirable bacteria in drinking water supply]. PMID- 4154634 TI - [Waste disposal in the hospital]. PMID- 4154635 TI - [Textile floor coverings: present hygienic situation]. PMID- 4154636 TI - [The influence of textile floor covering upon bacterial concentration in the air]. PMID- 4154637 TI - [Artificial ventilation and bacterial concentration in the hospital]. PMID- 4154638 TI - [Control of hospital air hygiene]. PMID- 4154639 TI - [Studies of the problem of air filtration]. PMID- 4154640 TI - [Air cleaning equipment: its effect upon the quality of indoor air]. PMID- 4154641 TI - [Requirements for drinking water. A critical review of guide-lines, ordinances, and laws]. PMID- 4154642 TI - [Bacterial contamination of indoor air as a function of air exchange]. PMID- 4154643 TI - [Comparative studies on the identification of E. coli in seawater]. PMID- 4154644 TI - [Hygienic-chemical studies of seawater in the coastal region]. PMID- 4154645 TI - [Toxicological evaluation of some nitrogen-containing substances in water of current interest]. PMID- 4154646 TI - [Studies of microbial growth on coating materials in water reservoirs]. PMID- 4154647 TI - [Ecophysiology of some aquatic bacteria from the Flavobacterium-Cytophaga group]. PMID- 4154649 TI - [Air-borne germ count in a ward for treatment of severe burns]. PMID- 4154648 TI - [Taxonomic studies of gram-positive organisms in sewage]. PMID- 4154650 TI - [Lipid structure of genus Bacteroides]. PMID- 4154651 TI - [Colonization of the turkey gut by gram-negative anaerobes]. PMID- 4154653 TI - [Leptotrichia buccalis--culture, biochemistry and antibiotics]. PMID- 4154652 TI - [Spread of extrachromosomal antibiotic resistance in the hospital]. PMID- 4154654 TI - [Contribution on the H2-O2 oxidoreductase system of Hydrogenomonas eutropha strain H 16: hydrogenase-defective mutants]. PMID- 4154655 TI - [Biochemical taxonomic studies of the genus Cellulomonas]. PMID- 4154656 TI - [Microbiological aspects of spontaneous and induced self-heating of peat]. PMID- 4154657 TI - [Rhizosphere organisms under the effect of environmental exposure to pesticides. I. Contribution on the problem of fungicide (TMTD equals tetramethylthiuram disulfide) determination in soils based on model experiments]. PMID- 4154658 TI - [Regulation of chromosomal transfer in Rhizobium lupini]. PMID- 4154659 TI - [Epidemiological importance of Pseudomonas aeruginosa within the framework of current hospital infections]. PMID- 4154661 TI - [Genetic studies of class P resistance factors in Rhizobium lupini]. PMID- 4154660 TI - [Sequential mutagenesis in Rhizobium lupini]. PMID- 4154662 TI - [Spontaneous induction of a defective Rhizobium lupini prophage]. PMID- 4154663 TI - [Characterization of a newly isolated Rhizobium lupini bacteriophage with a circularizing chromosome]. PMID- 4154664 TI - [Fine structure of the cell wall in various Cyanophyceae]. PMID- 4154665 TI - [Lipopolysaccharides from Rhodospirillaceae: composition and taxonomic relevance]. PMID- 4154666 TI - [The role of the cell membrane transport in glucose repression of induceable enzyme synthesis]. PMID- 4154667 TI - [The effect of urea on the cells and cell walls of Escherichia coli and Proteus mirabilis]. PMID- 4154668 TI - [Studies of the uptake of polyalcohols by the obligatory aerobe yeast Rhodotorula gracilis]. PMID- 4154669 TI - [Current problems of hospital infections in urology]. PMID- 4154670 TI - [Changes in the penicillin sensitivity of D-alanine-D-alanine carboxypeptidase of Proteus mirabilis following its conversion into the unstable L form]. PMID- 4154671 TI - [Antibiotics as an aid in the studies of cell division regulation in Escherichia coli]. PMID- 4154672 TI - [Murein-lipoprotein and receptor for phage T 5 and Colicin M: defined structural and functional areas of the outer membrane of Escherichia coli]. PMID- 4154673 TI - [Effect of polymyxin B on membranes and membrane components of Salmonella typhimurium]. PMID- 4154674 TI - [Vectorial phosphorylation, a mechanism of carbohydrate transport in bacteria]. PMID- 4154675 TI - [Inhibitors as modifiers of membrane permeability: cationic polypeptides and polysaccharides]. PMID- 4154676 TI - [Interaction of antibiotics and membranes--complex formation of bacitracin and membrane lipids]. PMID- 4154677 TI - [Demonstration of plasmid-specific DNA in staphylococci with multiple resistance]. PMID- 4154678 TI - [Current status of the resistance behavior of staphylococci to isoxazolyl penicillins (oxa-, cloxa-, and dicloxacillin)]. PMID- 4154679 TI - [Mechanism of bactericidal action of folic acid antagonists]. PMID- 4154680 TI - [Antibacterial activity of aminoglycoside antibiotics under reduced oxygen as well as under indreased CO2 pressure]. PMID- 4154681 TI - [Experimental studies of impaired fertility due to mycoplasma infections of the genital tract]. PMID- 4154682 TI - [New concepts in taxonomy of bifidobacteria]. PMID- 4154683 TI - [Experiences with Freter's anaerobic chamber in the clinical laboratory]. PMID- 4154684 TI - [Cell wall fine structure of Clostridium perfringens, Cl. septicum and Cl. novyi]. PMID- 4154685 TI - [Changes in body flora of hospital patients]. PMID- 4154686 TI - [Isolation and differentiation of Bacteroides, Fusobacterium and Sphaerophorus species]. PMID- 4154687 TI - [Clinical features and therapy of Bacteriodaceae]. PMID- 4154688 TI - [Nutritional requirements of Bacteroides melaninogenicus]. PMID- 4154689 TI - [Serological studies of Bacteroides melaninogenicus]. PMID- 4154690 TI - [Effect of anti-ulcer drugs on the contents of free amino acids in the mucosa of different parts of the stomach in experimental neurogenic dystrophy]. PMID- 4154691 TI - [Experience with clinical use of the drug gammalon in children with cerebral palsy]. PMID- 4154692 TI - [Nicotinic acid concentration in the blood and urine of syringomyelia patients during deep x-ray therapy]. PMID- 4154693 TI - The non-operative removal of retained common duct stones after biliary surgery. PMID- 4154694 TI - [Insights and therapeutic guidelines on the use of drugs in kidney insufficiency]. PMID- 4154695 TI - Effects of some drugs applied topically to the nasal mucosa before nasal provocation tests with allergen. PMID- 4154696 TI - Neuro-humoral concepts of bronchial asthma. PMID- 4154697 TI - Methoxyflurane and lipid and carbohydrate metabolism in rats. PMID- 4154698 TI - Histochemistry of primate laryngeal muscles. PMID- 4154699 TI - Graft-versus-host reactions mediated by a thymus-bone marrow combination, spleen cells, and lymph node cells from amyloidotic and nonamyloidotic mice. PMID- 4154701 TI - [Evaluation of psychological propensity to cardiovascular diseases]. PMID- 4154700 TI - Effects of prolonged treatment with adrenergic beta-receptor antagonists on blood pressure, cardiovascular design and reactivity in spontaneously hypertensive rats (SHR). PMID- 4154702 TI - The functional pattern of the cadaveric kidney in the early posttransplant period. PMID- 4154703 TI - Basic concepts of psychopharmacological research as applied to the psychopharmacological analysis of the amygdala. AB - Since the neural impulses in the brain are transmitted from one neuron to the next by various chemical mediators such as noradrenaline, dopamine, serotonin, acetylcholine, etc., the use of drugs acting specifically on one or more of these mediators should illucidate the chemical substrates of behavior. However, recent data indicating an extensive interaction between the various neurotransmitters on a cellular and even synaptic level, suggests that interpreting the behavioral effects of drugs in term of only one neurotransmitter is a potentially misleading oversimplification. Perhaps, rather than the action of a single neurotransmitter, it is the balance between neurotransmitter systems that determines behavior. Because of its rich innervation by noradrenaline, dopamine, serotonin and acetylcholine synapses, the amygdala is ideally suited for monitoring the balance between these neurotransmitters and altering maladaptive behavior based on fluctuations in neurotransmitter balance. PMID- 4154704 TI - The relationship of social and personality characteristics to hallucinogen use among college females. PMID- 4154705 TI - Postflight analysis of Bacillus thuringiensis organisms exposed to spaceflight conditions on Apollo 16. PMID- 4154706 TI - Dental development and trauma. PMID- 4154707 TI - Histamine H2 receptor antagonists. PMID- 4154708 TI - Three cases of pneumococcal bacteriuria. PMID- 4154709 TI - Rational use of psychotropic drugs II. Antianxiety agents. PMID- 4154710 TI - The effect of scopolamine on fetal heart rate baseline variability. PMID- 4154711 TI - [Intestinal suture. An animal experiment study and experiences with own suture technic]. PMID- 4154712 TI - Controlled emergence from anesthesia using the closed-circle system. PMID- 4154713 TI - Fluroxene toxicity in dogs: possible mechanisms. PMID- 4154714 TI - Cyclic nucleotides. PMID- 4154715 TI - Metabolic studies on heart of unweaned rabbits infected with foot-and mouth disease virus. PMID- 4154716 TI - Physician's assistants and clinical algorithms in health care delivery. A case study. PMID- 4154717 TI - [Endocrine function in 125 cases of cryptorchism]. PMID- 4154718 TI - Interaction of Na, K-ATPase with chlorpromazine free radical and related compounds. PMID- 4154719 TI - Red cell glucose-6-phosphate dehydrogenase deficiency in Finland. Further biochemical characterization of G-6-PD Helsinki. PMID- 4154720 TI - Detection of bacteremia by an automated radiometric method and a tubed broth method. PMID- 4154721 TI - Isoenzymes of creatine kinase; separation by acrylamide gel electrophoresis. PMID- 4154722 TI - Biochemical abnormalities in Reye's syndrome. PMID- 4154725 TI - Localization of the reaction site of cytochrome 552 in chloroplasts from Euglena gracilis. Effects of a specific antibody on endogenous, external and reincorporated cytochrome 552 in chloroplast membranes. PMID- 4154723 TI - [Reflections on some paradoxes of the human gonads (author's transl)]. PMID- 4154724 TI - Localization of the reaction site of cytochrome 552 in chloroplasts from Euglena gracilis. Cytochrome content and photooxidation in different chloroplast preparations. PMID- 4154726 TI - Mechanism of allylisopropylacetamide-induced increase of delta-aminolevulinate synthetase in liver mitochondria. Effects of administration of glucose, cyclic AMP, and some hormones related to glucose metabolism. PMID- 4154727 TI - Irreversible inactivation of rat liver tyrosine aminotransferase. PMID- 4154728 TI - Induction of tyrosine aminotransferase by Sepharose-insulin. PMID- 4154729 TI - Health care delivery in Cummins Engine Company. PMID- 4154730 TI - [Influence of sodium restitution on tyramine induced catecholamine liberation in auricules previously suspended in a sodium deficient medium]. PMID- 4154731 TI - [Effects of L-glutamine, pyridoxal and gamma aminobutyric acid on glycolysis and cerebral respiration]. PMID- 4154732 TI - [Technics of pharmacological studies of coronary circulation: angiocardiography and possibilities of fluorescent-coronary angiography and the orthotopic autotransplantation of the heart]. PMID- 4154733 TI - Effects of diazepam on cell division rates and productivity of Scenedesmus obliquus in Synchronous cultures. PMID- 4154734 TI - [Influence of continuous treatment with increasing doses of medazepam on a program of light discrimination]. PMID- 4154736 TI - Higher education in nursing. PMID- 4154735 TI - Effect of acute exposure to carbon disulfide vapour upon some components of the hepatic-microsomal enzyme system in rats. PMID- 4154737 TI - Beta-adrenergic blocking drugs. PMID- 4154738 TI - Seizure inhibition and REM sleep: a possible neurohumoral relationship. PMID- 4154739 TI - Abuse of psychopharmacological drugs--experiences in Norway. PMID- 4154740 TI - Clinical experience with pipothiazine palmitate (19552 R.P.) in hospitalized and open ward patients with functional psychoses. PMID- 4154741 TI - Subjective ratings of credibility following brief exposure to desensitization and pseudotherapy. PMID- 4154742 TI - Metabolic adaptations during lactogenesis. Fatty acid synthesis in rabbit mammary tissue during pregnancy and lactation. AB - 1. Mammary tissue was obtained from rabbits at various stages of pregnancy and lactation and used for tissue-slice incubations (to measure the rate of fatty acid synthesis and CO(2) production) and to determine relevant enzymic activities. A biphasic adaptation in fatty acid synthetic capacity during lactogenesis was noted. 2. The first lactogenic response occurred between day 15 and 24 of pregnancy. Over this period fatty acid synthesis (from acetate) increased 14-fold and the proportions of fatty acids synthesized changed to those characteristic of milk fat (77-86% as C(8:0)+C(10:0) acids). 3. The second lactogenic response occurred post partum as indicated by increased rates of fatty acid synthesis and CO(2) production (from acetate and glucose) and increased enzymic activities. 4. Major increases in enzymic activities between mid pregnancy and lactation were noted for ATP citrate lyase (EC 4.1.3.8), acetyl-CoA synthetase (EC 6.2.1.1), acetyl-CoA carboxylase (EC 6.4.1.2), fatty acid synthetase, glucose 6-phosphate dehydrogenase (EC 1.1.1.49), and 6 phosphogluconate dehydrogenase (EC 1.1.1.44). Smaller increases in activity occurred with glycerol 3-phosphate dehydrogenase (EC 1.1.1.8) and NADP(+) isocitrate dehydrogenase (EC 1.1.1.42) and the activity of NADP(+)-malate dehydrogenase (EC 1.1.1.40) was negligible at all periods tested. 5. During pregnancy and lactation there was a close temporal relationship between fatty acid synthetic capacity and the activities of ATP citrate lyase (r=0.94) and acetyl-CoA carboxylase (r=0.90). PMID- 4154743 TI - Regulation of the pentose phosphate cycle. AB - 1. A search was made for mechanisms which may exert a ;fine' control of the glucose 6-phosphate dehydrogenase reaction in rat liver, the rate-limiting step of the oxidative pentose phosphate cycle. 2. The glucose 6-phosphate dehydrogenase reaction is expected to go virtually to completion because the primary product (6-phosphogluconate lactone) is rapidly hydrolysed and the equilibrium of the joint dehydrogenase and lactonase reactions is in favour of virtually complete formation of phosphogluconate. However, the reaction does not go to completion, because glucose 6-phosphate dehydrogenase is inhibited by NADPH (Neglein & Haas, 1935). 3. Measurements of the inhibition (which is competitive with NADP(+)) show that at physiological concentrations of free NADP(+) and free NADPH the enzyme is almost completely inhibited. This indicates that the regulation of the enzyme activity is a matter of de-inhibition. 4. Among over 100 cell constituents tested only GSSG and AMP counteracted the inhibition by NADPH; only GSSG was highly effective at concentrations that may be taken to occur physiologically. 5. The effect of GSSG was not due to the GSSG reductase activity of liver extracts, because under the test conditions the activity of this enzyme was very weak, and complete inhibition of the reductase by Zn(2+) did not abolish the GSSG effect. 6. Preincubation of the enzyme preparation with GSSG in the presence of Mg(2+) and NADP(+) before the addition of glucose 6-phosphate and NADPH much increased the GSSG effect. 7. Dialysis of liver extracts and purification of glucose 6-phosphate dehydrogenase abolished the GSSG effect, indicating the participation of a cofactor in the action of GSSG. 8. The cofactor removed by dialysis or purification is very unstable. The cofactor could be separated from glucose 6-phosphate dehydrogenase by ultrafiltration of liver homogenates. Some properties of the cofactor are described. 9. The hypothesis that GSSG exerts a fine control of the pentose phosphate cycle by counteracting the NADPH inhibition of glucose 6-phosphate dehydrogenase is discussed. PMID- 4154744 TI - Mechanisms for the formation of alanine and aspartate on rat liver in vivo after administration of ammonium chloride. AB - 1. The time-course of the changes in the concentrations of hepatic metabolites in response to a non-toxic load of NH(4)Cl were measured in fed and starved rats. 2. There was a rapid increase (after 2min) in [alanine] and [aspartate] which remained high for 10-15min; the absolute increase in [alanine] was smaller in starved rats. 3. These changes were accompanied by a decrease in [oxoglutarate] and in the [3-hydroxybutyrate]/[acetoacetate] ratio. 4. Prior administration of l arginine to fed rats resulted in smaller increases in [alanine] and [aspartate] after the ammonia load. This is presumably due to stimulation of the urea cycle. 5. Increased formation of alanine in starved rats occurred after prior administration of dihydroxyacetone to increase the availability of pyruvate. 6. Administration of l-cycloserine, an inhibitor of glutamate-alanine aminotransferase, completely prevented the increase in [alanine] after the ammonia load; in this case the absolute increase in [aspartate] was higher. 7. [Oxoglutarate], [citrate] and [isocitrate] at 25min after the ammonia load were higher than the initial concentrations, but returned to normal by 50min. It is suggested that this ;overshoot' may be due to temporary compartmentation of oxoglutarate. 8. The mechanisms and physiological significance of alanine and aspartate formation in these experiments are discussed. PMID- 4154745 TI - The partial characterization of purified nitrite reductase and hydroxylamine oxidase from Nitrosomonas europaea. AB - Nitrite reductase has been separated from cell-free extracts of Nitrosomonas and partially purified from hydroxylamine oxidase by polyacrylamide-gel electrophoresis. In its oxidized state the enzyme, which did not contain haem, had an extinction maximum at 590nm, which was abolished on reduction. Sodium diethyldithiocarbamate was a potent inhibitor of nitrite reductase. Enzyme activity was stimulated 2.5-fold when remixed with hydroxylamine oxidase, but was unaffected by mammalian cytochrome c. The enzyme also exhibited a low hydroxylamine-dependent nitrite reductase activity. The results suggest that this enzyme is similar to the copper-containing ;denitrifying enzyme' of Pseudomonas denitrificans. A dithionite-reduced, 465nm-absorbing haemoprotein was associated with homogeneous preparations of hydroxylamine oxidase. The band at 465nm maximum was not reduced during the oxidation of hydroxylamine although the extinction was abolished on addition of hydroxylamine, NO(2) (-) or CO. These last-named compounds when added to the oxidized enzyme precluded the appearance of the 465nm absorption band on addition of dithionite. Several properties of 465nm-absorbing haemoprotein are described. PMID- 4154746 TI - Simulation of the pentose cycle in lactating rat mammary gland. AB - A computer model representing the pentose cycle, the tricarboxylic acid cycle and glycolysis in slices of lactating rat mammary glands has been constructed. This model is based primarily on the studies, with radioactive chemicals, of Abraham & Chaikoff (1959) [although some of the discrepant data of Katz & Wals (1972) could be accommodated by changing one enzyme activity]. Data obtained by using [1 (14)C]-, [6-(14)C]- and [3,4-(14)C]-glucose were simulated, as well as data obtained by using unlabelled glucose (for which some new experimental data are presented). Much past work on the pentose cycle has been mainly concerned with the division of glucose flow between the pentose cycle and glycolysis, and has relied on the assumption that the system is in steady state (both labelled and unlabelled). This assumption may not apply to lactating rat mammary glands, since the model shows that the percentage flow through the shunt progressively decreased for the first 2h of a 3h experiment, and we were unable to construct a completely steady-state model. The model allows examination of many quantitative features of the system, especially the amount of material passing through key enzymes, some of which appear to be regulated by NADP(+) concentrations as proposed by McLean (1960). Supplementary information for this paper has been deposited as Supplementary Publication SUP 50023 at the British Museum (Lending Division) (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies can be obtained on the terms indicated in Biochem. J. (1973) 131, 5. PMID- 4154747 TI - Pyridine nucleotide transhydrogenase activity of soluble cardiac NADH dehydrogenase and particulate NADH-ubiquinone reductase. PMID- 4154748 TI - The superoxide anion and singlet molecular oxygen: their role in the microbicidal activity of the polymorphonuclear leukocyte. PMID- 4154749 TI - Human erythrocyte glucose 6-phosphate dehydrogenase. Interaction with oxidized and reduced coenzyme. PMID- 4154750 TI - Interactions of alpha-methylfluorene-2-acetic acid with adenylate cyclase. PMID- 4154751 TI - Pharmacological inhibition of hormonal tyrosine amino transferase induction. PMID- 4154752 TI - Relationship between reduced nicotinamide adenine dinucleotide phosphate dependent lipid peroxidation and drug hydroxylation in rat liver microsomes. PMID- 4154753 TI - Protective effect of adenosine and nicotinamide against audiogenic seizure. PMID- 4154754 TI - Effect of phenobarbital on the incorporation of 3H or 14C labeled precursors into fatty acids. PMID- 4154755 TI - Effect of the convulsive agent 3-mercaptopropionic acid on the levels of GABA, other amino acids and glutamate decarboxylase in different regions of the rat brain. PMID- 4154757 TI - Workshop on the use of acupuncture in the rheumatic diseases. Summary of proceedings. National Institutes of Health, Bethesda, Maryland, September 17-18, 1973. PMID- 4154758 TI - Vasculitis of the breast: an unusual manifestation of polyarteritis. PMID- 4154756 TI - Periosteal new bone formation in polyarteritis nodosa: a syndrome involving the lower extremities. PMID- 4154759 TI - The synthesis and pharmacology of a novel benzodiazepine derivative, 1-methyl-5 (o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(ID-540). PMID- 4154761 TI - [Metabolism of bromo urea derivatives. 2. Characterization of acetylcarbromal deacetylating enzyme]. PMID- 4154760 TI - Central actions of some beta-adrenoceptor blocking agents. PMID- 4154762 TI - [Acute stress and pulmonary edema]. PMID- 4154763 TI - [Multifocal psychopharmaceutic testing ("Multihospital trial")]. PMID- 4154765 TI - Determination of dl-fencamine in rat and human urine. PMID- 4154764 TI - Comparison of beta-adrenergic blocking activities of propranolol, isopropylmethoxamine, sotalol, practolol, alprenolol, pindolol, oxprenolol and D 32 in the atria and trachea of the guinea-pig. PMID- 4154766 TI - Effects of Ko 1366 on the distribution of intrarenal blood flow in normal canine kidneys. PMID- 4154767 TI - [Clinical investigation of o-(2-hydroxy-3-(tert.-butylamino)-propoxy) benzonitrile under glucose load by means of continuous recording]. PMID- 4154768 TI - [Investigation of psychotropic substances in man]. PMID- 4154769 TI - [Experimental evaluation of the new cephalosporin antibiotic cephacetrile]. PMID- 4154770 TI - Tetracycline for the treatment of pityriasis lichenoides. PMID- 4154771 TI - Effect of propranolol on morphine metabolism. PMID- 4154772 TI - The estimation of enzyme activity in living epidermal cells. PMID- 4154774 TI - Genetic heterogeneity and pathophysiology of G6PD deficiency. PMID- 4154773 TI - The biochemical pharmacology of abused drugs. III. Cannabis, opiates, and synthetic narcotics. PMID- 4154775 TI - Nuclear magnetic resonance studies of the binding of substrate analogs and coenzyme to dihydrofolate reductase from Lactobacillus casei. PMID- 4154776 TI - The formation and characterization of the nicotine analog of triphosphopyridine nucleotide. PMID- 4154777 TI - Testosterone metabolism in rooster comb. PMID- 4154778 TI - The structure of ceramide aminoethylphosphonate from the sea anemone, Metridium senile. PMID- 4154779 TI - Trypsin inhibition of photosynthetic pyridine nucleotide reduction. PMID- 4154780 TI - Effect of alpha-tocopherol on reconstitution of photosystem I in heptane extracted spinach chloroplasts. PMID- 4154782 TI - Spectroscopic probes of Escherichia coli glutamine synthetase. Rare earth ions by difference absorption. PMID- 4154783 TI - Comparison of gastric and pancreatic inhibitory properties of metiamide and atropine. PMID- 4154781 TI - Malate dehydrogenase in Zea mays: properties and inhibition by sulfite. PMID- 4154784 TI - Splenic transplantation in Gaucher disease. PMID- 4154785 TI - [Peculiarities of detection and of cytospectrophotometric evaluation of enzymes in thyroid gland slices]. PMID- 4154786 TI - [Effect of phenibute (beta-phenyl-gamma-aminobutyric acid) on the hypophyseal adrenal system of rats]. PMID- 4154787 TI - Alteration of hepatic microsomal metabolism of male mice by certain anticholinesterase insecticides. PMID- 4154788 TI - Effect of dietary amino acids on hepatic drug metabolism in the rat. PMID- 4154789 TI - Metabolism of 3,4-benzpyrene in rainbow trout (Salmo gairdneri). PMID- 4154791 TI - Psychometric prediction of institutional adjustment: a validation study. PMID- 4154790 TI - Effect of catecholamines, serotonin, and some amino acids, injected into the amygdala, on the conditioned avoidance reflex and motor activity of rats. PMID- 4154792 TI - Pseudomonas osteomyelitis following puncture wounds in children. PMID- 4154793 TI - Blood and neoplastic diseases. Acute myeloblastic leukaemia. PMID- 4154794 TI - Optic and cochleovestibular degenerations in the hereditary ataxias. I. Clinico pathological and genetic aspects. PMID- 4154795 TI - Familial oculocranioskeletal neuromuscular disease with abnormal muscle mitochondria. PMID- 4154797 TI - Alterations in brain norepinephrine and tyrosine hydroxylase activity during experimental hypothyroidism in rats. PMID- 4154796 TI - The effect of barbiturates on (3H)GABA transport in rat cerebral cortex slices. PMID- 4154798 TI - Reserpine selectively increases tyrosine hydroxylase and dopamine-beta hydroxylase enzyme protein in central noradrenergic neurons. PMID- 4154799 TI - Differential effects of neuroleptic drugs on amphetamine-induced stimulation of locomotor activity in 11-day-old and adult rats. PMID- 4154800 TI - Gamma-aminobutyrate transaminase activity in rat cerebellar cortex: a histochemical study. PMID- 4154801 TI - [Irreducible cardiac insufficiency]. PMID- 4154802 TI - [Effect of fasting and hypophysectomy on the lipolytic and hyperglycemic action of adrenaline in dogs treated with beta blockaders]. PMID- 4154803 TI - A description of the embryology, larval development, and feeding of the sea anemones Anthopleura elegantissima and A. xanthogrammica. PMID- 4154804 TI - Prescription drugs and the patient's health. PMID- 4154805 TI - [Gamma GT in the diagnosis of primary and secondary hepatic neoplasms]. PMID- 4154806 TI - Total and regional coronary blood flow during acute right ventricular pressure overload. PMID- 4154807 TI - [Inhibition of platelet aggregation and its clinical use (author's transl)]. PMID- 4154808 TI - [Climacteric symptoms treated by Tacitin (author's transl)]. PMID- 4154809 TI - Correlation between azo reduction and formation in vitro of DNA-bound DAB metabolites in liver microsomes from rats fed on carcinogenic or normal diets. PMID- 4154810 TI - [Inhibition of de novo lipogenesis in rat, after ingestion of an anti-oxygen food additive: di-tert-butyl-hydroxy-toluene (BHT)]. PMID- 4154811 TI - [Regulation of NAD+ and NADP+ ferredoxin-reductase activities in Clostridium tyrobutyricum, cultivated on pyruvate]. PMID- 4154812 TI - [HbF synthesis in chicks irradiated and grafted with embryonic and adult hematopoietic tissues]. PMID- 4154813 TI - A kinetic determination of ammonia in plasma. PMID- 4154814 TI - [Decrease in serum gamma-glutamyltranspeptidase following abstention from alcohol]. PMID- 4154815 TI - Preservation of gamma-glutamyl transpeptidase activity in human urine. PMID- 4154816 TI - A fluorometric method for the measurement of butaperazine in human plasma. PMID- 4154817 TI - [Combination of adrenergic beta blockaders and antiarrhytamics drugs. Preclinical study]. PMID- 4154818 TI - A 3-year study among Yugoslavian schoolchildren on caries reduction after topical application of 4% NaF-PO4. PMID- 4154819 TI - Studies on the effect of dentifrices with low fluoride content. PMID- 4154820 TI - Oral health in the republic of Paraguay. PMID- 4154821 TI - A longitudinal study of caries experience and extraction of permanent first molars in English children. PMID- 4154822 TI - Effect of methionine sulfoximine on glutamine synthetase activity and blood metabolite levels in the chicken (Gallus domesticus). PMID- 4154823 TI - A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase. PMID- 4154824 TI - Respiratory enzymes of the silkmoth Antheraea pernyi in relation to metamorphosis and pupal diapause. PMID- 4154825 TI - The antispastic effects of Ba 34647 (B-4-p-chlorophenyl-gamma-amino-butyric acid) a GABA derivative. PMID- 4154826 TI - Effect of tolamolol versus propranolol on systolic time intervals in angina. PMID- 4154827 TI - Comparative in vitro activity of amoxicillin and ampicillin against bacteria isolated from ill children. PMID- 4154828 TI - [The political line is the key to training "red" and "expert" barefoot doctors]. PMID- 4154829 TI - [Barefoot doctors active in child health care]. PMID- 4154830 TI - [Serve the people wholeheartedly]. PMID- 4154831 TI - [Kinetics of microsomal hydroxylation of naphthalene]. PMID- 4154832 TI - [Electron microscopic study of the localization of succinate, lactate, and NAD-H2 dehydrogenases in aerobic bacterial membranes]. PMID- 4154833 TI - [Abuse of bromo-ureides and bromides. An acute addiction problem (author's transl)]. PMID- 4154834 TI - Baclofen: a preliminary report of its pharmacological properties and therapeutic efficacy in spasticity. PMID- 4154835 TI - Use of beta-adrenergic receptor blocking drugs in psychiatry. PMID- 4154836 TI - The clinical use of psychotherapeutic drugs in the elderly. PMID- 4154837 TI - Anaesthesia in the hypertensive patient. PMID- 4154838 TI - A practical approach to the management of angina. PMID- 4154839 TI - Enzyme histochemical study of fat absorption in human duodenal mucosa. AB - In seven healthy subjects the activities of various intestinal enzymes were studied using a fasting control peroral biopsy and two other biopsies 15 minutes and 30 minutes after an intestinal infusion of emulsified corn oil. Specific histochemical methods permitted the comparison of the enzymatic activities of the absorptive cells at the top of the villi before and during fat absorption which was demonstrated with a Sudan black stain. FOUR OXYDATIVE ENZYMES WERE MODIFIED AFTER THE CORN OIL INFUSION: NADH2-tetrazolium reductase, NADPH2-tetrazolium reductase, glucose-6-phosphate dehydrogenase, and lactate dehydrogenase. In six cases, the activity of NADH2-tetrazolium reductase was increased. Two of these subjects presented a simultaneous increase of NADPH2-tetrazolium reductase and glucose-6-phosphate dehydrogenase. Two other subjects presented a decrease in lactate dehydrogenase activity. PMID- 4154841 TI - An immunological approach to ferredoxin specificity and activity. PMID- 4154840 TI - An investigation into the enzyme histochemistry of adenocarcinomas of human large intestine and of the transitional epithelium immediately adjacent to them. AB - Histochemical enzymatic studies were performed on 30 freshly resected large bowel carcinomas, 30 samples of normal colonic epithelium, and six samples of the histologically normal epithelium (so-called transitional epithelium) immediately adjacent to a carcinoma. Five enzymes were studied: nicotine adenine dinucleotide tetrazolium reductase (NADH-TR), glucose-6-phosphate dehydrogenase, succinate dehydrogenase, monoamine oxidase, and acid phosphatase. QUANTITATIVE AND QUALITATIVE DIFFERENCES IN ENZYME ACTIVITY WERE OBSERVED BETWEEN NORMAL, TRANSITIONAL, AND CARCINOMATOUS MUCOSA AS FOLLOWS: monoamine oxidase activity was moderate in normal mucosa, high in transitional mucosa, and low in carcinoma. Succinate dehydrogenase activity was high in transitional mucosa and low or moderate in normal and carcinomatous mucosa. Glucose-6-phosphate dehydrogenase activity showed a gradation from low in normal mucosa to high in carcinoma while acid phosphatase showed the reverse of this pattern. The tetrazolium reductase activity was low or moderate in normal and transitional mucosa and high in carcinoma. These differences in enzyme activity and their possible clinical and metabolic significance are discussed. PMID- 4154842 TI - Reduction of adenosine 5'-phosphosulfate to cysteine in extracts from Chlorella and mutants blocked for sulfate reduction. PMID- 4154844 TI - Cell envelope composition of Escherichia coli K12: a comparison of the cell poles and the lateral wall. PMID- 4154843 TI - Studies with ubiquinone-depleted submitochondrial particles. Quantitative incorporation of small amounts of ubiquinone and its effects on the NADH and succinate oxidase activities. PMID- 4154845 TI - Possible role of cerebral amino acids in acute neurotoxic effects of DDT in mice. PMID- 4154846 TI - Effect of mianserin, a potent anti-serotonin agent, on the isolated rat stomach fundus preparation. PMID- 4154848 TI - Beta-adrenoceptor studies. III. On the beta-adrenoceptors in rat adipose tissue. PMID- 4154847 TI - Influence of autonomic blockade on the reduction in myocardial performance produced by clonidine. PMID- 4154849 TI - Long lasting stimulation of locomotor activity produced by the intraventricular injection of a cyclic analogue of dopamine into conscious mice. PMID- 4154850 TI - The nucleus amygdaloideus centralis and neuroleptic activity in the rat. PMID- 4154851 TI - The beta-blocking potency and cardioselectivity of tolamolol and its isomers in rodents. PMID- 4154852 TI - The effect of epinephrine following practolol on the pulmonary circulation of dogs. PMID- 4154854 TI - A thermodynamic approach to problems of drug antagonism. Measurements of the parameters of affinity (pA2) of antihistaminics and a beta-haloalkylamine under varying experimental conditions. PMID- 4154853 TI - Blockade by prostaglandins E2 and F1 alpha of the response of the rabbit ileum to stimulation of sympathetic nerve and its reversal by some antihistamines, dexamphetamine and methylphenidate. PMID- 4154856 TI - Anticonvulsant activity of some beta-adrenoceptor blocking agents in mice. PMID- 4154855 TI - Assessment of effects of beta-blocking drugs on blood glucose levels and insulin hypoglycaemia in rats. PMID- 4154857 TI - A vasodepressor action of histamine mediated by H2-receptor activation. PMID- 4154858 TI - Studies on the action and mechanism of action of oxyfedrine on isolated tracheal chains. PMID- 4154859 TI - Comparative effects of apomorphine, piribedil and other neurotropic agents on central analgesic-induced catatonia in the rat. PMID- 4154860 TI - Structure-selectivity relationships of beta-adrenoceptor antagonists in cats. PMID- 4154861 TI - Inhibition of in vitro stimulated gastric acid secretion by a histamine H2 receptor antagonist, metiamide. PMID- 4154862 TI - Nitrilophenoxypropanolamines: influence of ring substitution on beta-receptor blockade. PMID- 4154863 TI - Microspectrofluorometric evaluation of the oxygen probe 1-pyrene butyric acid in single living cells. PMID- 4154864 TI - Histochemical demonstration of gamma-glutamyltranspeptidase in rat liver after portacaval anastomosis. PMID- 4154865 TI - Local alpha-adrenoceptor mediated feed-back inhibition of catecholamine release from the adrenal medulla? PMID- 4154866 TI - Activity of some juvenoids in chironomid larvae. PMID- 4154867 TI - Subcellular distribution of catecholamines and enzymes in human neuroblastoma. PMID- 4154868 TI - Selectivity of beta-adrenergic compounds. III - Classification of beta-receptors. PMID- 4154869 TI - Kinetics of binding of oxidized coenzymes in ternary complexes with glutarate by L-glutamate dehydrogenase. PMID- 4154870 TI - Sequence of the reaction of heme catabolism catalyzed by the microsomal heme oxygenase system. PMID- 4154871 TI - Inhibition of steroid inducible tyrosine aminotransferase by mouse and rat interferon in hepatoma tissue culture cells. PMID- 4154872 TI - An investigation into the influence of a graft-versus-host reaction, induced by parent line cells, on the growth of lymphoma transplants in F1 hybrid mice. PMID- 4154873 TI - Blood lymphocyte nucleoli in ontogenesis and allograft reaction in normal and neonatally thymectomized mice. PMID- 4154874 TI - Possible role of serum factors in non-H-2 allograft response in mice. PMID- 4154875 TI - Analysis of some in vitro activities of rabbit and duck anti-chicken anti-brain sera. PMID- 4154876 TI - Popliteal lymph node activation in graft-versus-host and host-versus-graft reaction in mice. PMID- 4154877 TI - Effect of phytohaemagglutinin on graft-versus-host reaction in F1 hybrid mice. PMID- 4154878 TI - Effect of hepatocarcinogenic azo dyes on glutathione and related enzymes in rat liver. PMID- 4154879 TI - Congenital and hereditary abnormalities in the elderly. PMID- 4154880 TI - [Work capacity and the daily regimen for elementary school pupils studying under the new programs]. PMID- 4154881 TI - [Comparative evaluation of some current treatments of vibration-noise induced diseases]. PMID- 4154882 TI - Effect of calcitonin on the formation, composition, and enzymatic activity of the hepatic bile in guinea pgs. AB - Porcine calcitonin given to guinea pigs in doses causing hypocalcaemia and hypophosphataemia decreased the bilirubin concentration and increased the activity of gamma glutamyl transpeptidase (GGTP) in the hepatic bile. Calcitonin had no effect on bile flow, its pH, electrolyte composition including calcium, or on the concentration of protein, glucose, cholesterol, nonprotein nitrogen (NPN), and bile acids. It also did not affect the activities of alanine aminotransferase (AIAT) and alkaline phosphatase (AP) in the hepatic bile. Calcitonin increased the calcium content in the liver. PMID- 4154883 TI - [Spontaneous rupture of intrarenal aneurysms in periarteritis nodosa]. PMID- 4154884 TI - Atopic dermatitis anxiety and conditioned scratch responses. PMID- 4154885 TI - Verbal desensitisation in bronchial asthma. PMID- 4154886 TI - [An enzyme histochemical study on intestinal metaplasia of the gastric mucosa (author's transl)]. PMID- 4154887 TI - Enzymatic ribonucleotide reduction in wheat. PMID- 4154888 TI - [Biophysics of photosynthesis]. PMID- 4154889 TI - Hydroperoxide metabolism in hemoglobin-free perfused rat liver. PMID- 4154890 TI - 2-alkenal reductase isolation, properties and specificities. PMID- 4154891 TI - Mitochondrial nicotinamide nucleotide systems: ammonium chloride responses and associated metabolic transitions in hemoglobin-free perfused rat liver. PMID- 4154893 TI - [A reductive enzymic ester cleavage of steroid acetates in the microsomal fraction of liver (author's transl)]. PMID- 4154892 TI - Measurement of the ATP/ADP ratio in mitochondria and in the extramitochondrial compartment by fractionation of freeze-stopped liver tissue in non-aqueous media. PMID- 4154894 TI - NADP-specific glutamate dehydrogenase from Plasmodium chabaudi. PMID- 4154895 TI - [Hydroxysteroid oxidoreductases and their function as catalysts of specific hydrogen transfer between steroid hormones in human placenta. II. Kinetic studies and hydrogen transfer between C-17 of estradiol-17 beta and C-20 or progesterone]. PMID- 4154896 TI - [Time course of the induction by cyclohexane of hydroxylases in mouse liver and a suitable parameter for hydroxylase activities (author's transl)]. PMID- 4154897 TI - [Monodehydro-L(plus)-ascorbate reducing systems in differently prepared pig liver microsomes (author's transl)]. PMID- 4154898 TI - Phospholipids as cinchocain action site during inhibition of lipoperoxidative reactions in rat liver microsomes. PMID- 4154899 TI - Invertebrate collagens: qualitative and quantitative studies on their carbohydrate moieties. PMID- 4154900 TI - [Solubilization and purification of the NADPH-cytochrome reductase from rat liver microsomes (author's transl)]. PMID- 4154901 TI - [Conversion of 3beta-hydroxy-5-pregnen-20-one (pregnenolone) by Streptomyces hydrogenans (author's transl)]. PMID- 4154902 TI - [The slow dissociation of the NADH-dehydrogenase complex as a basis for the preferential transfer of hydrogen between the C-17 positions of steroids (author's transl)]. PMID- 4154904 TI - Editorials: Intestinal shunting for morbid obesity. PMID- 4154903 TI - Manpower: How five nations respond to the issues. PMID- 4154905 TI - Medical malpractice: viewpoint of a plaintiff's attorney. PMID- 4154906 TI - A children's hospital in Chicago, 1882-1904. PMID- 4154907 TI - The importance of vehicles in topical applications. PMID- 4154908 TI - Angiomatous lymphoid hamartoma of the mediastinum. PMID- 4154909 TI - Experience with the halo and body cast in the ambulatory treatment of cervical spine fractures. PMID- 4154910 TI - Surgical grand rounds. Carcinoma of lip. PMID- 4154911 TI - Hyponatremia and central nervous system disease. PMID- 4154912 TI - Neurology--epilepsy and learning disorders. PMID- 4154913 TI - Effect of inhibition of the Hill reaction on polyribosomes level and on induced synthesis of nitrate and nitrite reductases in rice seedlings. PMID- 4154914 TI - Metabolism of glucose in cerebral cortex of rat in leptazol-induced convulsions and effect of gamma-aminobutyric acid on the same. PMID- 4154915 TI - Isolation and cofactor requirements of benzoic acid-4-hydroxylase from Aspergillus niger. PMID- 4154916 TI - Isocitrate dehydrogenase of soybeans. PMID- 4154917 TI - Casein-induced experimental amyloidosis. III. Response to mitogens, allogeneic cells, and graft-versus-host reactions in the murine model. PMID- 4154918 TI - Antihistaminic effect of a new piperazine derivative, 1-phenoxy-2-(N-methyl piperazino)-3-ephedrinopropane monohydrochloride. PMID- 4154919 TI - Letter: Interaction between piperazine and some phenothiazine derivatives. PMID- 4154920 TI - Vitamin E protects mice against Diplococcus pneumoniae type I infection. AB - Vitamin E protects nonimmunized and immunized mice against fatal Diplococcus pneumoniae type I (DpI) infection. A dietary supplementation of 180 mg of dl alpha-tocopheryl acetate per kg of diet increased survival of nonimmunized mice from 20 to 80% when challenged with 20 organisms, and of mice immunized with 0.5 ng of DpI polysaccharide from 15 to 70% when challenged with 20,000 organisms. The phagocytic index of immunized mice was four times higher in the 180-mg vitamin E group than in the control group. Both the survival and phagocytic index revealed a biphasic dose response, indicating a cause-effect relationship between phagocytosis and survival. Vitamin E also significantly increased the rate of carbon clearance from blood, indicating a general increase in phagocytic activity. The data indicated that increased macrophage activity probably aided by increased antibody production was the principal reason for increased protection. PMID- 4154921 TI - Lipid peroxidation in the killing of phagocytized pneumococci. AB - To directly examine the role of hydrogen peroxide in the killing of bacteria after ingestion by granulocytes, we have studied some of the events of phagocytosis of a mutant strain of pneumococci which is relatively deficient in peroxide production. The hydrogen peroxide-deficient pneumococci and the otherwise identical wild type were grown with [(14)C]arachidonic and [(3)H]palmitic acid labels to label their lipids with unsaturated and saturated fatty acids, respectively. They were then incubated with both normal and chronic granulomatous disease granulocytes. The rates of ingestion and bacterial killing and the stability of fatty acids in the cell-bacteria complex were followed. Radioactive carbon dioxide released from glucose was also independently followed to measure glucose oxidation. Ingestion was similar for all cell-bacteria combinations. Chronic granulomatous disease cells killed the peroxide-positive wild pneumococci much more effectively (20-fold) than the peroxide-deficient mutant. Normal cells killed both peroxide-positive and -negative strains effectively. A considerable loss of [(14)C]arachidonic acid ( approximately 40%) consistent with lipid peroxidation of this unsaturated fatty acid was observed in all normal cells and in chronic granulomatous disease cells with peroxide positive pneumococci. However, no loss of [(14)C]arachidonic acid occurred in chronic granulomatous disease cells with the peroxide-deficient pneumococci. No loss tritiated palmitic acid occurred in any cell-bacteria combination. Glucose oxidation was impaired in the chronic granulomatous disease cells in comparison to normal cells at rest and was especially impaired in chronic granulomatous disease cells ingesting the peroxide-deficient mutant pneumococci. This defect was partially corrected after phagocytosis of the peroxide-positive strain. These data directly support the hypothesis that bacterial killing is partially dependent upon an intact peroxide-generating system in the leukocyte-bacteria complex. Moreover, they indicate that bacterial lipid peroxidation is associated with the generation of peroxide during phagocytosis. Finally, they suggest that such peroxidation may contribute to effective phagocytic bacterial killing. PMID- 4154922 TI - Effect of progesterone on Neisseria gonorrhoeae. AB - The effects of progesterone on the growth of pathogenic and nonpathogenic species of Neisseria were studied in liquid cultures. Only strains of N. gonorrhoeae and N. meningitidis were highly sensitive to growth inhibition by progesterone. This inhibitory effect was either bacteriostatic or bactericidal, depending upon the ratio of progesterone concentration to cell mass. The site of progesterone inhibition appeared to be located in the cell membrane; >86% of [4 (14)C]progesterone was recovered in the lipid-containing cell fractions. Membrane preparations from N. gonorrhoeae bound progesterone more efficiently than those from progesterone-insensitive cells. In addition, progesterone significantly inhibited the activity of the membrane-associated enzymes reduced nicotinamide adenine dinucleotide oxidase and (cytochrome b) l-lactate dehydrogenase. PMID- 4154923 TI - A university system drug profile. PMID- 4154924 TI - Influence of some psychoactive drugs on mineral metabolism in man. PMID- 4154925 TI - [Eye findings in rheumatic diseases]. PMID- 4154926 TI - Proteins of two strains of mosquito iridescent virus. PMID- 4154927 TI - A simplified guide to the rational use of psychotropic drugs. PMID- 4154928 TI - A medical classification system for ambulatory-care manpower planning. PMID- 4154929 TI - A microspectrofluorometric approach for the study of benzo(a)pyrene and dibenzo(a, h)anthracene metabolization in single living cells. PMID- 4154930 TI - Microspectrofluorometric study of benzo(a)pyrene metabolization in benzo(a)pyrene grown single living cells. PMID- 4154931 TI - Pleuropulmonary manifestations of collagen diseases. PMID- 4154932 TI - Purification and characterization of the two 6-phosphogluconate dehydrogenase species from Pseudomonas multivorans. AB - The two species of 6-phosphogluconate dehydrogenase (EC 1.1.1.43) from Pseudomonas multivorans were resolved from extracts of gluconate-grown bacteria and purified to homogeneity. Each enzyme comprised between 0.1 and 0.2% of the total cellular protein. Separation of the two enzymes, one which is specific for nicotinamide adenine dinucleotide phosphate and the other which is active with nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotide phosphate was facilitated by the marked difference in their respective isoelectric points, which were at pH 5.0 and 6.9. Comparison of the subunit compositions of the two enzymes indicated that they do not share common peptide chains. The enzyme active with nicotinamide adenine dinucleotide was composed of two subunits of about 40,000 molecular weight, and the nicotinamide adenine dinucleotide phosphate specific enzyme was composed of two subunits of about 60,000 molecular weight. Immunological studies indicated that the two enzymes do not share common antigenic determinants. Reduced nicotinamide adenine dinucleotide phosphate strongly inhibited the 6-phosphogluconate dehydrogenase active with nicotinamide adenine dinucleotide by decreasing its affinity for 6-phosphogluconate. Guanosine 5'-triphosphate had a similar influence on the nicotinamide adenine dinucleotide phosphate-specific 6-phosphogluconate dehydrogenase. These results in conjunction with other data indicating that reduced nicotinamide adenine dinucleotide phosphate stimulates the conversion of 6-phosphogluconate to pyruvate by crude bacterial extracts suggest that in P. multivorans, the relative distribution of 6 phosphogluconate into the pentose phosphate and Entner-Doudoroff pathways might be determined by the intracellular concentrations of reduced nicotinamide adenine dinucleotide phosphate and purine nucleotides. PMID- 4154933 TI - Sporulation properties of cytochrome a-deficient mutants of Bacillus subtilis. AB - Three classes of cytochrome a-deficient mutants of Bacillus subtilis have been found to be asporogenic or oligosporogenic. All three classes showed declines in adenosine 5'-triphosphate (ATP) concentrations during early sporulation, at a time when ATP levels in wild-type strains are constant. Class III mutants were found to be deficient in aconitase and isocitric dehydrogenase, and showed reduced maximum growth in nutrient sporulation medium. These mutants also suffered the most rapid decline in ATP concentration in early sporulation, and exhibited neither the biphasic oxygen consumption curve nor the increase in pH normally observed at the end of logarithmic growth in nutrient sporulation medium. Nicotinamide adenine dinucleotide oxidase activities of purified membrane preparations were approximately normal for mutants in all classes, except for two of the class II mutants and one class III mutant. Neither cytochrome a nor cytochrome c appears to be an obligatory intermediate in cyanide-sensitive nicotinamide adenine dinucleotide oxidation in B. subtilis. PMID- 4154934 TI - Purification and characterization of the Pseudomonas multivorans glucose-6 phosphate dehydrogenase active with nicotinamide adenine dinucleotide. AB - The Pseudomonas multivorans glucose-6-phosphate dehydrogenase (EC 1.1.1.49) active with nicotinamide adenine dinucleotide, which is inhibitable by adenosine 5'-triphosphate, was purified approximately 1,000-fold from extracts of glucose grown bacteria, and characterized with respect to subunit composition, response to different inhibitory ligands, and certain other properties. The enzyme was found to be an oligomer composed of four subunits of about 60,000 molecular weight. Reduced nicotinamide adenine dinucleotide phosphate, but not reduced nicotinamide adenine dinucleotide, was found to be a potent inhibitor of its activity. The range of concentrations of reduced nicotinamide adenine dinucleotide phosphate over which inhibition occurred was about 100-fold lower than that for adenosine-5'-triphosphate. The data suggest that reduced nicotinamide adenine dinucleotide phosphate may play an important role in regulation of hexose phosphate metabolism in P. multivorans. Antisera prepared against the purified enzyme strongly inhibited its activity, but failed to inhibit the activity of the nicotinamide adenine dinucleotide phosphate-specific glucose-6-phosphate dehydrogenase which is also present in extracts of this bacterium. Immunodiffusion experiments confirmed the results of the enzyme inhibition studies, and failed to support the idea that the two glucose-6 phosphate dehydrogenase species from P. multivorans represent different oligomeric forms of the same protein. PMID- 4154935 TI - Involvement of threonine dehydratase in biosynthesis of the alpha-ketobutyrate prosthetic group of urocanase. AB - Seventeen mutants of Pseudomonas putida that were unable to grow on threonine as nitrogen source owing to a lack of threonine dehydratase were isolated, and all were found to be unable to synthesize active urocanase. Spontaneous revertants selected for urocanase production concomitantly regained threonine dehydratase. Mutants that were unable to utilize urocanate as carbon source were also isolated, and these were defective in urocanase formation but were normal in threonine dehydratase levels. Since alpha-ketobutyrate is the prosthetic group for urocanase, these results are consistent with the proposal that threonine dehydratase is necessary for urocanase prosthetic group biosynthesis. However, the lack of urocanase activity in threonine dehydratase-negative mutants was shown not to be the result of reduced levels of endogenous free alpha ketobutyrate, nor to the participation of threonine dehydratase in the initiation of urocanase biosynthesis through the conversion of threonyl-tRNA(Thr) to alpha ketobutyryl-tRNA(Thr). Other alternatives for the participation of threonine dehydratase in urocanase biosynthesis are discussed. PMID- 4154937 TI - Structure and function of D-amino acid oxidase. VIII. Circular dichroism study in the ultraviolet region. PMID- 4154936 TI - Inhibition of induction of competence in Pneumococcus by isologous teichoic acid. AB - Pneumococcal teichoic acid inhibits induction of competence in incompetent cells of Pneumococcus. The inhibitory effect is very similar to that observed in the presence of d-glucosamine and d-galactosamine. PMID- 4154938 TI - The redox reactions in propionic acid fermentation. IV. Participation of menaquinone in the electron transfer system in Propionibacterium arabinosum. PMID- 4154939 TI - Cellular senescence in yeast caused by carbon-source starvation. II. Induction and subcellular location of lipid peroxidation activity. PMID- 4154940 TI - Is cytochrome oxidase a constituent of nuclear membranes? PMID- 4154941 TI - Ornithine cyclase (deaminating). III. Mechanism of the conversion of ornithine to proline. PMID- 4154942 TI - Purification and properties of the Neurospora crassa assimilatory nitrite reductase. PMID- 4154943 TI - Monovalent cation effects on lysine-sensitive aspartokinase catalytic activity and allosteric regulation. PMID- 4154944 TI - Interaction of gamma-glutamyl transpeptidase with amino acids, dipeptides, and derivatives and analogs of glutathione. PMID- 4154945 TI - The alpha-glycerophosphate cycle in Drosophila melanogaster. IV. Metabolic, ultrastructural, and adaptive consequences of alphaGpdh-l "null" mutations. AB - "Null" mutations previously isolated at the alphaGpdh-1 locus of Drosophila melanogaster, because of disruption of the energy-producing alpha glycerophosphate cycle, severely restrict the flight ability and relative viability of affected individuals. Two "null" alleles, alphaGpdh-1(BO-1-4), and alphaGpdh-1(BO-1-5,) when made hemizygous with a deficiency of the alphaGpdh-1 locus, Df(2L)GdhA, were rendered homozygous by recombination with and selective elimination of the Df(2L)GdhA chromosome. After over 25 generations, a homozygous alphaGpdh-1(BO-1-4) stock regained the ability to fly despite the continued absence of measurable alphaGPDH activity. Inter se heterozygotes of three noncomplementing alphaGpdh-1 "null" alleles and the "adapted" alphaGpdh-1(BO-1-4) homozygotes were examined for metabolic enzymatic activities related to the energy-producing and pyridine nucleotide-regulating functions of the alpha glycerophosphate cycle in Drosophila. The enzyme functions tested included glyceraldehyde-3-phosphate dehydrogenase, cytoplasmic and soluble malate dehydrogenase, lactate dehydrogenase, mitochondrial NADH oxidation, oxidative phosphorylation, and respiratory control with the substrates alpha glycerophosphate, succinate, and pyruvate. These activities in any of the mutant genotypes in early adult life were indistinguishable from those in the wild type. There was, however, a premature deterioration and atrophy of the ultrastructural integrity of flight muscle sarcosomes observed by electron microscopy in the "null" mutants. These observations were correlated with a decrease in state 3 mitochondrial oxidation with alpha-glycerophosphate, succinate, and pyruvate, as well as with loss of respiratory control in adults as early as 2 wk after eclosion. Such observations, which normally are seen in aged dipterans, were accompanied by premature mortality of the mutant heterozygotes. The adapted alphaGpdh-1(BO-1-4) was identical with wild type in each of the aging characters with the single exception of lowered rates of mitochondrial oxidative phosphorylation. PMID- 4154946 TI - The biosynthesis and turnover of nicotinamide adenine dinucleotide in enucleated culture cells. PMID- 4154947 TI - The distribution of pyridine nucleotides between nucleus and cytoplasm. PMID- 4154948 TI - An apparatus for the detection and quantitation of volatile human effluents. PMID- 4154949 TI - Gas chromatographic analysis of medazepam and its metabolites using an electrolytic conductivity detector. PMID- 4154951 TI - Cardiac function in patients treated with phenothiazines. Comparison with quinidine. PMID- 4154952 TI - An initial investigation of the psychedelic drug flashback phenomena. PMID- 4154950 TI - Comparison of the effects on renin release of beta adrenergic antagonists with differing properties. AB - Continuous 6-h infusions of the beta adrenergic blockers d,l-propranolol or oxprenolol significantly reduced plasma renin activity (PRA) and mean blood pressure in the resting rabbit and prevented the stimulatory effects of isoproterenol on renin release and heart rate. These actions were due to blockade of beta receptors, for the inactive isomer, d-propranolol, had no effect. Despite sustained high plasma concentrations of d,l-propranolol (0.2 mug/ml) in the unstimulated animal, PRA did not fall below 36% of control values, suggesting that basal renin secretion is maintained partly by factors other than beta adrenergic mechanisms.Prindolol, another beta blocker, also abolished the effects of isoproterenol on renin and on the heart, and reduced blood pressure in the resting animal. However, prindolol increased resting PRA and heart rate, and in animals already receiving d,l-propranolol, it raised PRA and heart rate without further altering blood pressure. This suggests that the effect on PRA of prindolol was due to its intrinsic sympathomimetic activity and not hypotension mediated mechanisms. The observation that the blood pressure-lowering effect of prindolol was associated with a rise in PRA, while another beta antagonist, H 35/25, lowered PRA but had no effect on blood pressure, indicates that the hypotensive action of beta blockers is unrelated to their effects on renin release. In both unstimulated and isoproterenol-challenged animals, only blockers possessing beta-1 receptor affinity (d,l-propranolol, oxprenolol, prindolol, practolol, and metoprolol) affected heart rate, while effects on PRA were more prominent with agents possessing beta-2 activity (d,l-propranolol, oxprenolol, prindolol, and H 35/25). Thus, the changes in PRA caused by the beta adrenergic blockers appear to be dependent upon the summation of their direct effects, antagonistic or sympathomimetic, on beta-2 adrenergic receptors regulating renin release. PMID- 4154953 TI - The structure of word storage in the permanent memory of nonpsychotic schizophrenics. PMID- 4154954 TI - Use of sensory deprivation in facilitating the reduction of cigarette smoking. PMID- 4154955 TI - Reactions of internal and external test-anxious students to counseling and behavior therapies. PMID- 4154956 TI - Acid-etched resin splint for temporarily stabilizing anterior teeth. PMID- 4154957 TI - The use of liquid and gel isoelectric focusing as a means of further evaluating the degree of restriction of rabbit antibodies. PMID- 4154958 TI - [Effect of alpha-blocking agents and their importance in heart surgery - effects on the reserve potentials of the heart]. PMID- 4154959 TI - [Isolation of enzyme-substrate complex (author's transl)]. PMID- 4154960 TI - Piperacetazine study in state hospital patients. PMID- 4154961 TI - Physician's assistants and rural health care: a study of physician's attitudes. PMID- 4154962 TI - Physiological studies of conducting systems in the colonial hydroid Hydractinia echinata 1. Polyp specialization. PMID- 4154963 TI - Morphological substrates of conduction in the colonial hydroid Hydractinia echinata. 1. An ectodermal nerve net. PMID- 4154964 TI - Intracellular actions of 5-hydroxytryptamine on the bivalve myocardium. 1. Adenylate and guanylate cyclases. PMID- 4154965 TI - The regulation of glutamine metabolism in Candida utilis: mechanisms of control of glutamine synthetase. PMID- 4154967 TI - Nitrite and ammonia assimilation by anaerobic continuous cultures of Escherichia coli. PMID- 4154966 TI - A comparative study of cells and mitochondria of Saccharomyces cerevisiae and of a hydrocarbon-utilizing yeast, Candida lipolytica. PMID- 4154968 TI - The enzymes of ammonia assimilation in Schizosaccharomyces spp. and in Saccharomycodes ludwigii. PMID- 4154969 TI - The pentobarbital test dose for depressant drug dependence. PMID- 4154970 TI - Utility of three abbreviated MMPIs with psychiatric outpatients. PMID- 4154971 TI - Regional changes in amino acid content in developing rat brain. PMID- 4154972 TI - Free amino acids in the photoreceptor cells of the frog retina. PMID- 4154973 TI - Evidence for specific synaptosomal localization of exogenous accumulated taurine. PMID- 4154974 TI - Sodium-dependent efflux and exchange of GABA in synaptosomes. PMID- 4154975 TI - Effect of riboflavin and riboflavin 2',3',4',5'-tetrabutyrate on rat liver microsomal lipid peroxidation. PMID- 4154976 TI - The occurrence and properties of methylenetetrahydrofolate dehydrogenase in pea seedlings, and intracellular distribution of some folate-linked enzymes in the plant. PMID- 4154977 TI - The relation between urinary excretion of tryptophan and niacin metabolites and pyridine nucleotides in the liver in rats fed a tryptophan-deficient diet. PMID- 4154978 TI - Studies on D-tetrose metabolism. V. Identification of protecting factor against cold inactivation of D-erythrulose reductase from beef liver. PMID- 4154979 TI - Mosquito transmission of Plasmodium (Giovannolaia) circumflexum Kikuth, 1931, to waterfowl in the Tantramar Marshes, New Brunswick. PMID- 4154980 TI - An observation of an unusual repair of an osseous defect. PMID- 4154981 TI - Spectrophotometric determination of ampicillin sodium in the presence of its degradation and polymerization products. PMID- 4154982 TI - Detection, isolation and characterization of normorphine and norcodeine as morphine metabolites in man. PMID- 4154983 TI - A polarographic method for the determination of the N-oxide, N-oxide-sulphoxide and sulphoxide metabolites of chlorpromazine. PMID- 4154984 TI - A quantitative gas-liquid chromatographic method for phorbol and related diterpenes as their acetates. PMID- 4154985 TI - The cannabinoid content of Cannabis sativa L grown in England. PMID- 4154986 TI - The influence of porosity upon the distribution of reserpine in calcium sulphate granules. PMID- 4154987 TI - The response of isolated cardiac muscle to acute anoxia: protective effect of adenosine triphosphate and creatine phosphate. PMID- 4154988 TI - Histamine, 5-hydroxytryptamine, kinins and the anti-inflammatory activity of human plasma fraction in carrageenan-induced paw oedema in the rat. PMID- 4154990 TI - Inhibition by non-steroidal anti-inflammatory agents of the release of rabbit aorta contracting substance and prostaglandins from chopped guinea-pig lungs. PMID- 4154989 TI - Effect of a sea snake (Enhydrina schistosa) venom on the ganglionic nicotinic actions of acetylcholine. PMID- 4154991 TI - Long-lasting anti-tremor induced by 2-Br-alpha-ergocryptine in monkeys. PMID- 4154992 TI - Further evidence for the stimulation of rat brain dopamine receptors by ergometrine. PMID- 4154993 TI - The effect of beta-phenethylamine on noradrenaline and dopamine turnover in rat brain. PMID- 4154994 TI - Effect of muscarinic agonists on the release of (3H)noradrenaline from the guinea pig perfused heart. PMID- 4154995 TI - Further observations on the relaxant effect of caerulein on the guinea-pig ileum. PMID- 4154996 TI - The effect of amphetamine on glucose uptake into the rat isolated hemidiaphragm. PMID- 4154997 TI - Influence of different anions on tyramine and amphetamine uptake by cow adrenal medulla chromaffin vesicles. PMID- 4154998 TI - The role of solvent interaction in quantum pharmacological studies. PMID- 4154999 TI - Structure of an acidic metabolite of delta1-tetrahydrocannabinol isolated from rabbit urine. PMID- 4155000 TI - Characteristics of the mass spectra of some aliphatic amine N-oxides. PMID- 4155001 TI - Plasma and urine concentrations of a new adamantane derivative. PMID- 4155002 TI - Isosalsolinol formation: a secondary reaction in the Pictet-Spengler condensation. PMID- 4155003 TI - The effect of particle size reduction on digoxin crystal properties. PMID- 4155004 TI - Effect of maleic acid in compendial UV absorption assays for antihistamine maleate salts. PMID- 4155005 TI - Caries-experience of preschool children in selected day-care centers. PMID- 4155006 TI - Rats, flies and mosquitos of Lebanon: pests, reservoirs and vectors of disease. PMID- 4155007 TI - Optometrists as ancillary personnel. PMID- 4155008 TI - Influence of the beta-adrenergic blocking drug Ko 1366 on haemodynamics in healthy volunteers and patients with ischaemic heart disease. PMID- 4155010 TI - [Partial gastric secretion in patients with ulcer disease during treatment with Filatov's serum and benzoheonium]. PMID- 4155009 TI - Carotid reconstruction for Takayasu's (pulseless) disease using open thromboendarterectomy at aortocarotid junction. PMID- 4155011 TI - [Effebt of altered gaseous atmosphere and increased temperature on human respiration and gas exchange in a confined enclosed space]. PMID- 4155012 TI - Portacaval shunt in the pig 1. Effect on survival, behavior, nutrition, and liver function. PMID- 4155014 TI - [Trauma and scleroderma]. PMID- 4155013 TI - [Creation of a sensitive finger pad after traumatic amputation of the distal phalanx]. PMID- 4155015 TI - [2 cases of reconstruction of soft tissue defects of the face caused by human bite]. PMID- 4155016 TI - [Simultaneous closed luxation of the carpo-metacarpal joints]. PMID- 4155017 TI - [A new method for the classification of fractures. The ACD code]. PMID- 4155018 TI - [Nailing the femur neck, using a faulty technic]. PMID- 4155019 TI - [Pelvic osteotomy (Salter's operation)]. PMID- 4155020 TI - [The role of arteriography in the reconstruction of severe hand injuries]. PMID- 4155021 TI - [Recurrent fracture following removal of metal plates, securing stable fixation]. PMID- 4155022 TI - [Results of treatment with the Pavlik stirrup in congenital hip dislocation]. PMID- 4155023 TI - [Covered nailing of pertrochanteric fractures of the femur]. PMID- 4155024 TI - [Measurements of the circulation in the femur head in the light of histological examinations]. PMID- 4155025 TI - [Hypophyseal changes associated with skull injuries]. PMID- 4155026 TI - [Alveolar surface membrane of the lung]. PMID- 4155027 TI - [Crystal synovitis with generalized cartilage calcification]. PMID- 4155028 TI - [Shoveller's disease]. PMID- 4155029 TI - [Errors in the osteosynthesis of humeral fractures]. PMID- 4155030 TI - Characteristics of physician's assistants: a focus on specialty. PMID- 4155031 TI - Manpower in obstetrics--gynecology in a period of declining birth rate. PMID- 4155033 TI - [Increasing life expectancy through hygienic measures]. PMID- 4155034 TI - [Effect of nutrition, drug therapy and environment on population growth]. PMID- 4155032 TI - Pancreatic tumors and the first hormones. PMID- 4155035 TI - [Functional electrocardiography in medical practice]. PMID- 4155036 TI - [509 cases of acute exogenous poisoning]. PMID- 4155037 TI - [Diagnosis and prognosis in primary glaucoma]. PMID- 4155038 TI - [Modern lung examination]. PMID- 4155039 TI - [Clinical use of adrenergic beta blockaders]. PMID- 4155040 TI - Lipid peroxidation in chronic ethanol treated rats: in vitro uncoupling of peroxidation from reduced nicotine adenosine dinucleotide phosphate oxidation. PMID- 4155041 TI - [Proceedings: Therapy of chronic hepatitis using D-penicillamine. Symposium of the 1st medical clinic of the Nuernberg City Hospital (3. 1. 1974)]. PMID- 4155043 TI - Factors in oxygen delivery to tissue. PMID- 4155042 TI - Determination of the activity of succinate, NADH, choline, and alpha glycerophosphate dehydrogenases. PMID- 4155044 TI - [Possibilities in the prevention of myocardial infarct]. PMID- 4155045 TI - [Inhibition of labour. Symposium by letter (author's transl)]. PMID- 4155046 TI - [The effect of the calcium inhibitors verapamil (Isoptin) und D 600 on the side effects of the inhibition of labour with the beta-adrenergic drug Th 1165 a (Partusisten)]. PMID- 4155047 TI - MMTP: a patient-oriented view. PMID- 4155048 TI - Detection of the use of methaqualone and benzodiazepines in urine screening programs. PMID- 4155049 TI - Tyrosine-dependent increase of tyrosine hydroxylase in neuroblastoma cells. PMID- 4155051 TI - Effects of an antispastic drug (beta-(4-chlorophenyl)-gamma-aminobutyric acid) on Renshaw cell activity. PMID- 4155052 TI - Inhibitory and disinhibitory effects of nitrazepam, diazepam and flurazepam hydrochloride on delayed matching behaviour in monkeys (Macaca mulatta). PMID- 4155050 TI - Evidence that punctate intracerebral administration of 6-hydroxydopamine fails to produce selective neuronal degeneration. Comparison with copper sulfate and factors governing the deportment of fluids injected into brain. PMID- 4155053 TI - Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat. PMID- 4155055 TI - Inhibition of the catalytic site of adenylate cyclase in the central nervous system by phenothiazine derivatives. PMID- 4155054 TI - The blockade of bulbospinal inhibition by imipramine, desipramine and pargyline. PMID- 4155056 TI - Renal transplant recipients. Significance of bacterial infections. PMID- 4155057 TI - Acute iron poisoning in infancy. Guide to treatment. PMID- 4155058 TI - Fluorosis and dental caries in the Ellice Islands. PMID- 4155059 TI - Second messenger system in neoplasia. PMID- 4155060 TI - [Plastic repair of defects in the supporting surfaces of the foot using a combined flat flap]. PMID- 4155061 TI - [Device for the reduction of malleolar fractures complicated by subluxations of the foot and divergence of the intertibiofibular articulation]. PMID- 4155062 TI - Dental needs of Minnesota's head start children. PMID- 4155063 TI - [The place of cromolyn (lomudal, intal, aarane) in the management of bronchial asthma (author's transl)]. PMID- 4155064 TI - [Etiology of necrotic changes in organs of fattened geese. II. Attempts at infecting geese with S. necrogenes and prophylactic action of chlorocycline Polfa and deworming with carbon tetrachloride]. PMID- 4155065 TI - [18th Congress of Polish surgeons in Katowice]. PMID- 4155066 TI - [Unwanted pregnancy: background and psychological characteristics of women who choose abortion (author's transl)]. PMID- 4155067 TI - Tyrosine hydroxylase: activation by nerve stimulation. AB - The synthesis of the sympathetic neurotransmitter, norepinephrine, is accelerated by electrical stimulation of the guinea pig vas deferens. The molecular mechanism responsible for this enhanced formation of transmitter is unknown but has been attributed to an increase in the activity of tyrosine hydroxylase (EC 1.14.16.2; tyrosine 3-monooxygenase) during nerve stimulation. In the present experiments, we found that crude preparations of tyrosine hydroxylase isolated from guinea pig vasa deferentia that were electrically stimulated or depolarized by potassium show an increase in activity compared with enzyme obtained from untreated paired control tissues. This increase in activity is partially antagonized by addition of the Ca(++) chelator, ethylene glycol bis(beta-aminoethyl ether)-N,N' tetraacetic acid (EGTA), to the assay medium, and can be completely blocked if Ca(++) is removed from the potassium-rich medium used to depolarize the intact tissue, before preparation of the enzyme. A similar increase in enzyme activity occurs when Ca(++) ions are added directly to enzyme prepared from untreated vasa deferentia. In this instance, the activation is completely reversed by EGTA. The increase in activity produced by addition of Ca(++) to the isolated enzyme or by electrical stimulation or potassium depolarization of the tissue before isolation of the enzyme appears to be mediated by changes in the kinetic properties of tyrosine hydroxylase. All treatments appear to activate tyrosine hydroxylase by causing an increase in its affinity for substrate and pteridine cofactor and by decreasing its affinity for the end-product inhibitor, norepinephrine. These results provide direct evidence that the enhanced formation of norepinephrine seen during stimulation of sympathetically innervated tissues arises from an activation of tyrosine hydroxylase. The fact that the activation produced by nerve stimulation is mimicked by Ca(++) ions raises the intriguing possibility that the influx or mobilization of Ca(++) that accompanies nerve stimulation and that is intimately involved in release of transmitter may also participate in the activation of tyrosine hydroxylase. PMID- 4155068 TI - Amino-acid sequence of NADP-specific glutamate dehydrogenase of neurospora crassa. AB - A tentative primary structure of the NADP-specific glutamate dehydrogenase [L glutamate: NADP oxidoreductase (deaminating), EC 1.4.1.4] from Neurospora crassa has been determined. The proposed sequence contains 452 amino-acid residues in each of the identical subunits of the hexameric enzyme. Comparison of the sequence with that of the bovine liver enzyme reveals considerable homology in the amino-terminal portion of the chain, including the vicinity of the reactive lysine, with only shorter stretches of homology within the carboxyl-terminal regions. The significance of this distribution of homologous regions is discussed. PMID- 4155069 TI - Phosphoprotein phosphatase activity associated with estrogen-induced protein in rat uterus. AB - Estrogen-induced protein was purified from rat uteri and assayed for several enzymatic activities involved in the metabolism and action of cyclic nucleotides. No adenylate and guanylate cyclase (EC 4.6.1.1 and 4.6.1.2, respectively), protein kinase (EC 2.7.1.33), and cyclic nucleotide binding activities could be demonstrated in three independent preparations of the protein. However, all three preparations exhibited significant phosphoprotein phosphatase activity (EC 3.1.3.16) on phosphorylated protamine and histones F1. This activity is optimal at neutral pH, inhibited by Zn(++), and unaffected by cyclic AMP or cyclic GMP. PMID- 4155070 TI - Glucose inhibition of epinephrine stimulation of hepatic gluconeogenesis by blockade of the alpha-receptor function. AB - For isolated rat hepatocytes, glucagon, 3':5'-cyclic AMP, 3':5'-cyclic GMP, and epinephrine stimulate the rate of gluconeogenesis from substrates not involving pathways of mitochondrial metabolism. From estimation of the rates of glucose formation, fructose 6-phosphate phosphorylation, and lactate and pyruvate formation it is concluded that epinephrine and 3':5'-cyclic GMP stimulate gluconeogenesis from either galactose or fructose by influencing the rate of reactions involving fructose 6-phosphate in a manner similar to that already reported for glucagon and 3':5'-cyclic AMP. Each agent acts to inhibit flux through phosphofructokinase (EC 2.7.1.11) and enhance flux through fructose diphosphatase (EC 3.1.3.11), resulting in the re-direction of carbon from lactate and pyruvate formation to glucose synthesis. In addition to 3':5'-cyclic GMP, dibutyryl 3':5'-cyclic GMP, 8-bromo 3':5'-cyclic GMP, 8-benzyl-thio 3':5'-cyclic GMP and 8-(4-chlorophenyl)thio 3':5'-cyclic GMP stimulate glucose formation and inhibit lactate and pyruvate formation from galactose. Guanosine monophosphate and 2':3'-cyclic GMP are inactive. As the stimulatory effect of epinephrine is inhibited by phenoxybenzamine and not by propranolol, and is not simulated by isoproterenol, it is concluded that catecholamine activity is expressed through the alpha-receptor. Increased extracellular glucose concentration (>10 mM) decreases the stimulatory effect of epinephrine, 3':5'-cyclic GMP, and partially that of 3':5'-cyclic AMP but does not alter the efficacy of glucagon. PMID- 4155071 TI - Biosynthesis of tyrosine hydroxylase in rat adrenal medulla after exposure to cold. AB - Exposure of rats to cold increases the content of tyrosine hydroxylase [EC 1.14.16.2; L-tyrosine, tetrahydropteridine:oxygen oxidoreductase (3 hydroxylating)] in adrenal medulla, causing a long-lasting enhancement of the enzymatic activity. We have used an antibody specific to tyrosine hydroxylase to study the molecular mechanisms involved in the trans-synaptic induction of adrenal tyrosine hydroxylase. The rate of [(3)H]-leucine incorporation into adrenal tyrosine hydroxylase was measured by specific immunoprecipitation at various times after exposure to cold (4 hr). This enhanced rate of incorporation was evident between 11 and 30 hr after the beginning of exposure to cold, but not at 7 and 50 hr. The increase of (3)H incorporation preceded the maximal enhancement of adrenal tyrosine hydroxylase activity, which occurred about 30 hr after stimulation. Neither the activity of tyrosine hydroxylase nor the rate of (3)H incorporation into tyrosine hydroxylase in cervical sympathetic ganglia was changed by 4 hr of exposure to cold. The rate of degradation of tyrosine hydroxylase was estimated at 26 and 50 hr after the beginning of cold stress, as determined by the technique of double-isotope labeling. The data indicate that the tyrosine hydroxylase degradation rate was not reduced by exposure to cold. Thus, the induction of adrenal tyrosine hydroxylase appears to be due to an increased rate of its synthesis. PMID- 4155072 TI - Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system. AB - [(3)H]Gamma-aminobutyric acid (GABA) binds to synaptic membrane fractions of rat brain in a selective fashion representing an interaction with postsynaptic GABA receptors. Inhibition of [(3)H]GABA binding by a variety of amino acids closely parallels their ability to mimic the synaptic inhibitory actions of GABA and does not correlate with their relative affinity for the presynaptic synaptosomal GABA uptake system. [(3)H]GABA binding is saturable with an affinity constant of about 0.1 muM. The GABA antagonist bicuculline inhibits [(3)H]GABA binding with half maximal effects at 5 muM, whereas it requires a concentration of 0.5 mM to reduce synaptosomal GABA uptake by 50%. In subcellular fractionation experiments [(3)H]GABA binding is most enriched in crude synaptic membranes. [(3)H]GABA binding is greatest in the cerebellum, least in the spinal cord and medulla oblongatapons, with intermediate values in the thalamus, hippocampus, hypothalamus, cerebral cortex, midbrain, and corpus striatum. PMID- 4155074 TI - Aberrations of cyclic nucleotide metabolism in the hearts and vessels of hypertensive rats. AB - In the aortas and mesenteric arteries from spontaneous hypertensive rats and in the aortas from stress- and desoxycorticosterone-acetate-hypertensive rats, the intracellular cGMP: cAMP ratios were significantly elevated when compared to the ratios in the aortas of the respective controls. Decreases in the intracellular cAMP or cGMP levels were consistently associated with increased activity of the cyclic-nucleotide-specific low K(m) phosphodiesterase (3':5'-cAMP 5' nucleotidohydrolase, EC 3.1.4.17). Increases in intracellular cGMP levels were associated with elevated guanylyl cyclase [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] activity. Furthermore, adenylyl cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] activity was less sensitive to stimulation by the beta adrenergic stimulant isoproterenol in both the aortas and the hearts of the hypertensive animals. These changes could provide the biochemical basis for the (a) increased vascular smooth muscle tone and peripheral resistance observed in these animals, (b) increased reactivity to norepinephrine, and (c) decreased ability of aortas from hypertensive rats to relax. The presence of these same effects in different etiologic types of hypertension indicates that this aberration in cyclic nucleotide metabolism may represent a common metabolic defect basic to the hypertensive syndrome irrespective of etiology. PMID- 4155073 TI - Heterogeneity of membrane vesicles from Escherichia coli and their subfractionation with antibody to ATPase. AB - The energy-transducing, Mg-Ca activated ATPase (ATP phosphohydrolase, EC 3.6.1.3) of E. coli is located on the inner surface of the cytoplasmic membrane. Antibody to purified ATPase has now been used to demonstrate that membrane vesicles as ordinarily prepared by the lysozyme-EDTA method consist of two distinct populations. About half the vesicles are everted, and thus readily agglutinated by antibody to ATPase, while half are right-side out. NADH oxidase (reduced NAD:O(2) oxidoreductase EC 1.6.99.3) activity is associated almost entirely with everted vesicles, while the ability to concentrate proline is a property of the right-side out vesicles. The results explain the failure of previous workers to observe the energization of membrane vesicles by oxidation of NADH. PMID- 4155075 TI - Problems in immunology. PMID- 4155076 TI - Present controversies in the treatment of schizophrenia. PMID- 4155078 TI - Indirect evidence for superoxide anion and singlet oxygen generated by NADPH- NADPH-dependent cytochrome c reductase and by L-alpha-hydroxyacid--L-amino acid oxidase at high pH. PMID- 4155077 TI - Synthesis of acetyl coenzyme A holocarboxylase in vitro by a cytosolic preparation from chicken liver. PMID- 4155079 TI - Effect of heparin treatment on GVH disease. PMID- 4155080 TI - Effect of microsomal enzyme inducers on the liver changes produced by common bile duct ligature. PMID- 4155081 TI - Influence of adrenergic drugs on prostaglandin E release from the dog kidney,. PMID- 4155082 TI - Effect of barbiturates and isoniazid on cerebral hemisphere gamma-aminobutyric acid content in pp' DDT treated mice. PMID- 4155083 TI - [Progress in the field of drug development. 7]. PMID- 4155084 TI - [The analysis and stability of various 1,4-benzodiazepines of pharmaceutical interest. 2. Ring contraction of nordiazepam and clonazepam. pH-Dependence of hydrolytic cleavage of diazepam(Faustan) and use of kinetic methods for determination of stability behavior of diazepam in solutions of the ampoules]. PMID- 4155085 TI - One-step isolation and characterization of nuclear membranes. PMID- 4155086 TI - Complex envelope system. Membrane systems of plant cells. PMID- 4155087 TI - Structural studies relating to the distribution of molecular components in erythrocyte membranes. PMID- 4155088 TI - The ultrastructure and chemistry of the luminal plasma membrane of the mammalian urinary bladder: a structure with low permeability to water and ions. PMID- 4155089 TI - Membranes and membrane surfaces. Dynamics of cytoplasmic membranes in pancreatic acinar cells. PMID- 4155090 TI - Membranes. Freeze-etching techniques applied to biological membranes. PMID- 4155091 TI - Form and function of the glycocalyx on free cell surfaces. PMID- 4155092 TI - Nuclear envelopes. Structure and biochemistry of the nuclear envelope. PMID- 4155093 TI - Nuclear pores at prophase of meiosis in plants. PMID- 4155094 TI - Varieties of depression in one patient. PMID- 4155095 TI - Bibliography on behavioral approaches to modification of smoking: January 1964 through December 1973. PMID- 4155096 TI - Covert reinforcement and self-control procedures in systematic desensitization of gagging behavior. PMID- 4155097 TI - Personality characteristics of female narcotic addicts on the MMPI. PMID- 4155098 TI - Need for establishing desensitization programs on university campuses. PMID- 4155099 TI - Social introversion-extraversion and Rorschach human responses in adult psychiatric patients. PMID- 4155100 TI - Lethality of suicidal behavior and the MMPI. PMID- 4155102 TI - [Results of fluoridation and outlook for its growth in Germany]. PMID- 4155103 TI - Immunologic activation of oncogenic viruses. PMID- 4155104 TI - Animal response to meteorological stress as a function of age. PMID- 4155105 TI - [The place of controlled hypotension in odonto-stomatology]. PMID- 4155106 TI - [NADH oxidation by Mycobacterium lepraemurium]. PMID- 4155107 TI - The use of pins in the restoration of mutilated teeth. PMID- 4155108 TI - [Behavior of the enzymes gamma-glutamyl transpeptidases leucine aminopeptidase, lactate dehydrogenase and alpha-hydroxybutyrate dehydrogenase in the urine of hepatobiliary patients]. PMID- 4155109 TI - Subfractions obtained from inner mitochondrial membranes incubated with cysteine. II. Distribution of enzymes and respiratory chain components. PMID- 4155110 TI - An enzymatic basis for a blood-brain barrier? The gamma-glutamyl cycle-background and considerations relating to amino acid transport in the brain. PMID- 4155111 TI - Implications of catecholamine systems of the brain in schizophrenia. PMID- 4155112 TI - [Current therapeutic trends in clinical medicine. I]. PMID- 4155113 TI - [Malignant hypertension]. PMID- 4155114 TI - [Heart hypertrophy]. PMID- 4155115 TI - [Performance and diagnostic value of telemetric heart-volume determination in supine position as illustrated by comparison with angiographically determined heart volume]. PMID- 4155116 TI - [Life expectancy of patients with valvular defects]. PMID- 4155117 TI - [Significance of elevated enzyme activities in the diagnosis of heart infarct]. PMID- 4155118 TI - [Rejection of legal action following contract withdrawal by the insurance carrier due to violation of the precontract obligation to provide health information]. PMID- 4155119 TI - [Mechanical support of the failing heart using arterial counter-pulsation]. PMID- 4155120 TI - [Effects of the benzodiazepines on the intra-ocular pressure of patients with glaucoma]. PMID- 4155121 TI - Response of the bronchial tree to chemical stimuli. PMID- 4155122 TI - Bronchoconstriction tests in epidemiology. Discussion. PMID- 4155123 TI - [Bronchoconstriction tests in epidemiology. Conclusions of the 3d session]. PMID- 4155124 TI - Bronchoconstriction tests in epidemiology. Summary and conclusions of the meeting. PMID- 4155125 TI - [Determination of ICSH (LH) in urine of boys with undescended testes by means of hemagglutination inhibition tests]. PMID- 4155126 TI - [Pericarditis in rheumatoid polyarthritis. Apropos of a study of 19 cases]. PMID- 4155127 TI - [Effects of immunosuppressive agents on renal and other changes in (NZBX NZW)F1 hybrid New Zealand mice]. PMID- 4155129 TI - [Education and utilization of medical assistants in the Mongolian People's Republic and their professional prospects]. PMID- 4155128 TI - Oral metiamide as an effective inhibitor of gastric acid secretion in man. PMID- 4155130 TI - Fetal laryngeal and tracheal transplants in rats. PMID- 4155131 TI - Assessment of immunocompetency by DNCB sensitization prior to human renal allotransplantation. PMID- 4155132 TI - Effect of heparin, dextran and dipyridamole on the immunogenicity of renal allografts. PMID- 4155133 TI - Immunological responses in transplantation of canine small intestine. PMID- 4155134 TI - Effects of metiamide, a histamine H2-receptor antagonist, on vagally induced gastric secretion in dogs. PMID- 4155135 TI - Tumor growth and lymphatic vasculature of free grafts and skin pedicles. PMID- 4155136 TI - Selective gondal angiography for testicular localization in patients with cryptorchism. PMID- 4155137 TI - [Effect of adrenoblockaders on gastric secretion and intragastric pH in patients with peptic ulcer]. PMID- 4155138 TI - [Problems in drug therapy of hypertension]. PMID- 4155139 TI - [Treatment of bronchial asthma]. PMID- 4155140 TI - [Treatment of undescended testis with reference to the fertility rate]. PMID- 4155141 TI - [Orthopaedical care of the traumatized foot (author's transl)]. PMID- 4155142 TI - [Distorsio pedis (author's transl)]. PMID- 4155143 TI - [Acute coronary heart disease: diagnosis and first care at home (author's transl)]. PMID- 4155144 TI - Degradation of red cell membrane phospholipids by sea anemone nematocyst venom. PMID- 4155145 TI - Actions of Chironex fleckeri toxins on cardiac transmembrane potentials. PMID- 4155146 TI - Toxicological evaluation of palytoxin in several animal species. PMID- 4155147 TI - The low molecular weight fraction of sea wasp (Chironex fleckeri) venom. PMID- 4155148 TI - Different ways of using graft-versus-host reactivities to achieve acceptance of rat spleen allografts in the same donor-recipient pairing. PMID- 4155149 TI - Bone marrow transplantation: introduction. PMID- 4155150 TI - Bone-marrow transplantation in France, 1958-1973. PMID- 4155151 TI - Allogeneic marrow grafts in man using cyclophosphamide. PMID- 4155152 TI - Bone-marrow transplantation following combination chemotherapy immunosuppression (B.A.C.T.) in patients with acute leukemia. PMID- 4155153 TI - Histopathology of graft-vs.-host reaction (GvHR) in human recipients of marrow from HL-A-matched sibling donors. PMID- 4155154 TI - Strategy of clinical bone-marrow transplantations with emphasis on treatment of combined immune deficiency. PMID- 4155155 TI - Fatal graft-vs.-host reaction following transfusion of allogeneic blood and plasma in infants with combined immunodeficiency disease. PMID- 4155156 TI - Infectious complications of marrow transplantation. PMID- 4155157 TI - Proposal for a world bank of reactive cells from bone marrow. PMID- 4155158 TI - Allogeneic marrow transplantation using matched sibling donors. PMID- 4155159 TI - Use of ionizing radiation in transplantation. PMID- 4155161 TI - Chromosomes of golden hamster tumors obtained by tumoral polypassage of the RS 1 rat tumor. PMID- 4155160 TI - Histopathology in clinical renal transplantation. PMID- 4155162 TI - [Etyprenalin (Numotac, Riker)]. PMID- 4155163 TI - Caveat myxoma. PMID- 4155164 TI - [Objective control of the depth of neuroleptoanalgesia]. PMID- 4155165 TI - [Subcutaneous administration of nitrous oxide for analgesic purposes]. PMID- 4155166 TI - [Effect of adrenergic beta-blockade using trimepranol on glucose, insulin, somatotropin and nonesterified fatty acids in the blood of women with diabetes mellitus]. PMID- 4155167 TI - [Possibilities for the clinical use of bone marrow]. PMID- 4155168 TI - [Blastomogenic and immunodepressive characteristics of SA7(C8) virus]. PMID- 4155169 TI - [Biological variants of the tick-borne encephalitis virus isolated in various foci of the disease]. PMID- 4155170 TI - Pharmacokinetic criteria for the evaluation of retard formulations. PMID- 4155171 TI - [The serum gamma-glutamyltranspeptidase level in clinical diagnosis (author's transl)]. PMID- 4155172 TI - [DNA-synthesizing lymphocytes in the blood of patients with disseminated lupus erythematosus, rheumatoid arthritis, and panarteritis nodosa (author's transl)]. PMID- 4155173 TI - [Diagnostic and therapeutic possibilities in the orthostatic syndrome]. PMID- 4155174 TI - [Pathology of collagen diseases as a manifestation of disorders in connective tissue perfusion, connective tissue cleansing and foreign-body elimination]. PMID- 4155175 TI - [Maldescensus testis]. PMID- 4155176 TI - [Definition and content in the concept of standard, variation, anomaly and abnormality]. PMID- 4155177 TI - About the hazard of obtaining false information as to oxygen supply to tissues by the hitherto used method of monitoring patients during extracorporeal circulation. PMID- 4155178 TI - [Crohn's disease in the colon]. PMID- 4155179 TI - [Study of the course of Crohn's disease under Imurel treatment]. PMID- 4155180 TI - [The significance of the hydrogen ion concentration and the addition of ADP in the determination of ammonia with glutamate dehydrogenase. An improved enzymic determination of ammonia, I (author's transl)]. PMID- 4155181 TI - [Direct determination of plasma ammonia without deproteinization. An improved enzymic determination of ammonia, II (author's transl)]. PMID- 4155182 TI - [Determination of gamma-glutamyl transpeptidase in the urine of normal persons and patients with kidney disease, using an automatic kinetic method (author's transl)]. PMID- 4155183 TI - [Interference by glutathione reductase in the GSH-activated determinated of creatine kinase in serum (author's transl)]. PMID- 4155184 TI - New substrates for measuring gamma-glutamyl transpeptidase activity. PMID- 4155185 TI - Studies on glutathione reductase in serum. PMID- 4155186 TI - Molar extinction coefficients of NADH and NADPH at Hg spectral lines. PMID- 4155187 TI - On the quality of reduced pyridine coenzymes. PMID- 4155188 TI - A simple method for the determination of enzyme activities in turbid plasma of patients with hyperlipoproteinemia. PMID- 4155189 TI - Normal values of enzyme activities during pregnancy. PMID- 4155190 TI - A glucose-determination on mechanized analyzers using glucose-dehydrogenase. PMID- 4155191 TI - [Effect of anesthesia with non-barbiturate preparations on gas exchange under conditions of normal ventilation and experimental hypoxia]. PMID- 4155192 TI - [Comparative characteristics of the recovery period in ambulatory patients after various types of intravenous general anesthesia]. PMID- 4155193 TI - Toxicology of some autopsy cases involving tricyclic antidepressant drugs. PMID- 4155194 TI - Report on a lethal antazoline intoxication. PMID- 4155195 TI - [Clinical aspects and therapy of septic shock with urogenital etiology]. PMID- 4155196 TI - [Isolation of vaccinia virus from dermovaccine. A comparative study of modern preparative methodes for vaccine production. II. Zonal centrifugation in sucrose density gradient and differential centrifugation (author's transl)]. PMID- 4155197 TI - Haemagglutination-inhibiting antibodies to arboviruses in a human population in Greece. PMID- 4155198 TI - [Studies on the standardisation of the technique for the preparation of primary cell cultures from tissues of the fresh water teleostei (author's transl)]. PMID- 4155199 TI - [Isolation of "clumping factor" of Staphylococcus aureus (author's transl)]. PMID- 4155200 TI - Evaluation of the immunofluorescent reagents in the identification of Salmonella bacteria. PMID- 4155201 TI - [Investigations on the epidemiology and control of plague in South Vietnam. Part I (author's transl)]. PMID- 4155202 TI - [Investigations on the epidemiology and control of plague in South Vietnam. Part II (author's transl)]. PMID- 4155203 TI - [Sulphated glycosaminoglycans as virus inhibitors. 1st communication: The effect of sulphated glycosaminoglycans in different virus-host systems as demonstrated by the plaque inhibition test (author's transl)]. PMID- 4155204 TI - [Studies on bacterial intestinal flora of young rabbits in relation to diet and age (author's transl)]. PMID- 4155205 TI - [Oral immunization with non-viable micro-organisms or their antigens. 18. Communication. Capability of storage of lyophilised oral-vaccines (author's transl)]. PMID- 4155206 TI - [Occurrence of neuraminidase and acylneuraminate lyase in Clostridium beijerinckii and Clostridium tertium (author's transl)]. PMID- 4155207 TI - [The antibody titer and fluorescence suitability of semliki forest virus immune sera (author's transl)]. PMID- 4155208 TI - [Nalidixic acid for the isolation of streptococci with swarming Proteus (author's transl)]. PMID- 4155209 TI - A modified microslide gel double diffusion test. PMID- 4155210 TI - [The estimation of the molecular weight of bacterial neuraminidases by gel filtration (author's transl)]. PMID- 4155211 TI - [Investigations on the effect of crystal violet on Salmonella R mutants. 2. Communication. Experiments on respiration inhibition and inactivation (author's transl)]. PMID- 4155212 TI - A rapid method of identifying Escherichia coli H antigens. PMID- 4155213 TI - Isolation of two strains of Klebsiella pneumoniae with transferable resistance determinants against ten antimicrobial drugs from clinical material. PMID- 4155214 TI - [Pseudomonas maltophilia as an agent of infection in man (author's transl)]. PMID- 4155215 TI - Notes on the age and sex distribution of attack rates of clinical cholera in endemic urban area. PMID- 4155216 TI - [Finding of secondarily sensitive receptor cells in the aboral organ of ctenophores]. PMID- 4155217 TI - Future trends in antihypertensive therapy. PMID- 4155218 TI - [Auto-immune diseases and immunodepressive therapy. II. Current clinical indications]. PMID- 4155219 TI - The mode of action of the gaba derivative baclofen in human spasticy. PMID- 4155220 TI - Abnormal involuntary movements induced by anticholinergic therapy. PMID- 4155221 TI - Frequency of hypodontia in relation to tooth size and dental arch width. PMID- 4155222 TI - A histochemical study on the activity of gamma-glutamyl transpeptidase in liver disease. PMID- 4155223 TI - Pharmacological modification of glutathione and NADP+ reduction. PMID- 4155224 TI - Fetal outcome from prolonged versus acute drug administration in the pregnant rat. PMID- 4155226 TI - The function of alpha- and beta-adrenergic receptors and a cholinergic receptor in the secretory cell of rat parotid gland. PMID- 4155225 TI - The soluble acidic lipoproteins (SALPS) of storage granules. Matrix constituents which may bind stored molecules. PMID- 4155227 TI - Remarks on the organization of axon terminals in relation to secretory processes at synapses. PMID- 4155228 TI - Delayed increase of tyrosine hydroxylase activity induced by transsynaptic stimulation in chromaffin cells: role of cyclic nucleotides as second messengers. PMID- 4155229 TI - Disinhibition as an organizing principle in the nervous system. The role of gamma aminobutyric acid. PMID- 4155230 TI - Some neuroactive compounds in the substantia nigra. PMID- 4155232 TI - Effects of iron and copper deficiencies on monoamine metabolism. PMID- 4155231 TI - Evidence for descending pallido-nigral GABA-containing neurons. PMID- 4155233 TI - A new biosynthetic pathway to catecholamines via m-tyrosine. PMID- 4155234 TI - The clinical physiology of side effects in long-term L-DOPA therapy. PMID- 4155235 TI - The "on-off" effect. PMID- 4155236 TI - Some aspects of dopamine in the central nervous system. PMID- 4155237 TI - In vivo spontaneous and evoked release of newly synthesized dopamine in the cat caudate nucleus. PMID- 4155238 TI - The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine. PMID- 4155239 TI - [Iatrogenic effects on the salivary glands]. PMID- 4155240 TI - [Iatrogenic facial dyskinesia]. PMID- 4155241 TI - On the use of membrane feeding to study the development of Trypanosoma brucei in Glossina. PMID- 4155242 TI - Comparison of specific and relative alanine and aspartate aminotransferases of Trypanosoma brucei subgroup trypanosomes. PMID- 4155243 TI - [Ultrastructure and life cycle of Herpetomonas muscarum, "Herpetomonas mirabilis" and Crithidia luciliae in Chrysomyia chloropyga]. PMID- 4155244 TI - Necrotizing arteritis. PMID- 4155245 TI - Letter: Serum gonadotropins in cryptorchidism. PMID- 4155246 TI - ASMT position paper on physician extenders. PMID- 4155247 TI - Sympathetic nervous system and renin release from submaxillary glands and kidneys. PMID- 4155248 TI - Infection-induced hyperglucagonemia and altered hepatic response to glucagon in the rat. PMID- 4155249 TI - Effects of altitude and semistarvation on heart mitochondrial function. PMID- 4155250 TI - Evidence for presence of adrenergic receptors in the 6-day-old chick embryo. PMID- 4155251 TI - Directions for statutory change: The physician extender.. PMID- 4155252 TI - Prolactin and human breast cancer. PMID- 4155253 TI - Therapeutic effects of luteinizing hormone releasing hormone (LH-RH) in cryptorchidism. PMID- 4155254 TI - [So called hypoplastic zones and ring-like tubules of the human testes]. PMID- 4155255 TI - [Nasotracheal intubation in maxillofacial surgery using bronchofibroscopy]. PMID- 4155256 TI - Mechanism of action of some bronchodilators. Cyclic nucleotide metabolism in tracheal preparations. PMID- 4155257 TI - [Periarteritis nodosa and Australia antigen]. PMID- 4155258 TI - [Cardiological treatment and pregnancy]. PMID- 4155259 TI - Autonomic drugs in ophthalmology: some problems and promises. Section III: Sympathomimetic drugs. PMID- 4155260 TI - [Presence of autogenous characteristic in a Tunisian population of Culiseta (C.) subochrea (Edw., 1921) (Diptera-Culicidae)]. PMID- 4155261 TI - [Adrenergic receptors and beta-blocking agents in coronary pathology]. PMID- 4155262 TI - New and emerging roles in nursing. PMID- 4155263 TI - Virulence of Venezuelan equine encephalomyelitis virus subtypes for various laboratory hosts. AB - Mice, guinea pigs, and duck embryo cell cultures were inoculated with known subtypes of Venezuelan equine encephalomyelitis (VEE) virus and the attenuated (TC-83) strain of VEE. With the exception of TC-83, all strains were highly pathogenic for suckling mice by either intracranial or intraperitoneal routes of inoculation used. Virulence for older mice and guinea pigs provided a means to distinguish strains. In addition, virulence or lack of virulence for adult mice or guinea pigs provides a rapid method for separating epizootic subtype IB from TC-83 VEE virus isolates. PMID- 4155264 TI - Glucose 6-phosphate dehydrogenase from brewers' yeast (Zwischenferment). Further observations on the ligand-induced macromolecular association phenomenon: kinetic properties of the two-chain protein species; and studies on the enzyme-substrate interactions. PMID- 4155265 TI - Properties of leaf NAD malic enzyme from plants with C4 pathway photosynthesis. PMID- 4155266 TI - Action of diethylstilbestrol on the NADH-dehydrogenase region of the respiratory chain. PMID- 4155267 TI - The mechanism of cytochrome b5 reduction by NADPH-cytochrome c reductase. PMID- 4155268 TI - Different effects of 2-n-heptyl-4-hydroxyquinoline-N-oxide on oxygen and nitrate respiration in Klebsiella aerogenes. PMID- 4155269 TI - Effect of andrenalectomy on cyclic 3',5'-guanosine monophosphate metabolism of rat liver and other tissues. PMID- 4155270 TI - Chorismate synthase of Neurospora crassa: a flavoprotein. PMID- 4155271 TI - Substrate specificity of uptake of diamines in mouse brain slices. PMID- 4155272 TI - Proceedings: Antagonism of the histamine response in the synovial microcirculation. PMID- 4155273 TI - New evidence for the beta-adrenergic receptor blocking activity of dihydroergotamine. PMID- 4155274 TI - Pharmacology of sympathomimetic amines with beta-adrenoreceptor agonist and alpha adrenoreceptor antagonist properties. PMID- 4155275 TI - [Measurement of calcium influx after alpha-adrenergic stimulation of vascular smooth muscle]. PMID- 4155276 TI - Effects of diphenylaminoethanol (DPAE) on GABA and synaptic inhibitions in the cerebral and cerebellar cortices. PMID- 4155277 TI - Effect of small doses of clonazepam upon soman-induced seizure activity and convulsions. PMID- 4155278 TI - [Adrenergic components of direct coronary and cardiac action of nitroglycerin]. PMID- 4155279 TI - The antiarrhythmic effects of quaternary salts of beta-adrenergic blocking agents. PMID- 4155280 TI - Antagonism of acute lethality of narcotic analgesics in aggregated and isolated mice by the central cholinomimetic action of pilocarpine. PMID- 4155281 TI - The role of carotid sinus reflex, cardiac distention and catecholamines in the vagal escape mechanism. PMID- 4155282 TI - Purulent pericarditis in the antibiotic era. PMID- 4155283 TI - [Detection of sleeping pills in the skeleton and the soil after having lain in the forest for half a year]. PMID- 4155284 TI - Beta-adrenergic receptor blocking drugs in psychiatry. PMID- 4155285 TI - Neuropsychological assessment of undergraduate marihuana and LSD users. PMID- 4155286 TI - [Biopharmacological effects of coffee. Summary and conclusions]. PMID- 4155287 TI - [Evolution of the gravitation receptor and its study under conditions of acceleration and weightlessness]. PMID- 4155288 TI - Progesterone-induced lysis of rat kidney lysosomes as studied by changes in light absorbance. AB - 1. A rat kidney lysosomal fraction was prepared by the method of Maunsbach (1966) and characterized by its content of representative marker enzymes for lysosomes, mitochondria, peroxisomes and endoplasmic reticulum. 2. It was shown that both pH dependent and progesterone-induced lysis lead to a decrease in the E(520) of suspensions of this preparation. This decrease parallels quantitatively and temporally the release of soluble acid phosphatase. 3. It is suggested that E(520) measurements are a valid method for the continuous measurement of changes in lysosomal integrity. 4. As an example, results are included which demonstrate the ability of Zn(2+) to stabilize lysosomes against spontaneous and progesterone induced lysis. PMID- 4155289 TI - Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on liver constituents associated with folate metabolism. AB - 1. The effects of injected l-methionine (2g every second day for 28 days) on liver folates and other constituents of liver associated with folate metabolism were studied in vitamin B(12)-deficient ewes and their pair-fed controls receiving vitamin B(12). The dose rate of methionine used was sufficient to restore almost to normal the elevated excretion in the urine of formiminoglutamate in the deficient animals. 2. Liver folates active for Lactobacillus casei, Streptococcus faecalis R and Pediococcus cerevisiae were severely depressed in deficient livers and were partly restored by methionine. Analysis of the folates after ion-exchange chromatography showed that the major effect of methionine was to increase the concentrations of tetrahydrofolates and formyltetrahydrofolates. Methyltetrahydrofolates were also increased, but there was no effect of methionine on the small amounts of incompletely reduced folates present in deficient livers. The folates present were predominantly penta-, hexa- and hepta-glutamates whether or not animals received vitamin B(12) or methionine. 3. Concentrations of ATP, NAD(+), NADH and NADPH were lower in freeze-clamped liver from vitamin B(12)-deficient sheep than in liver from pair-fed, vitamin B(12)-treated sheep. These changes were not affected by methionine which was also without effect on the elevated K(+)/Na(+) ratios found in deficient livers. 4. The livers of vitamin B(12)-deficient animals contained lower concentrations of choline and higher concentrations of lipid than their pair-fed controls. These effects were reversed by methionine. PMID- 4155290 TI - Folic acid metabolism in vitamin B12-deficient sheep. Effects of injected methionine on methotrexate transport and the activity of enzymes associated with folate metabolism in liver. AB - 1. A study was made of the effects of injected l-methionine on the activity of several enzymes of folate metabolism, and on the transport of methotrexate in liver preparations from vitamin B(12)-deficient ewes and their pair-fed controls receiving vitamin B(12). 2. The activities of dihydrofolate reductase (EC 1.5.1.3) and 5-methyltetrahydrofolate-homocysteine transmethylase were significantly decreased in the liver of vitamin B(12)-deficient animals, but were unaffected by l-methionine. 3. The concentration of S-adenosyl-l-methionine in the liver of deficient animals was about one-half of that in normal animals, and was restored to normal by either vitamin B(12) or l-methionine. 4. Methylenetetrahydrofolate reductase (EC 1.1.1.68) from sheep liver was inhibited by S-adenosyl-l-methionine in vitro, but not by concentrations of S-adenosyl-l methionine found in the liver of vitamin B(12)-deficient animals after injection of physiological amounts of l-methionine. 5. Pteroylpolyglutamate synthetase activity was significantly increased in the liver of vitamin B(12)-deficient animals, and was decreased by intravenous injections of l-methionine. 6. l Methionine injections increased the initial rate of uptake of methotrexate in liver slices from deficient animals and acted synergistically with vitamin B(12) to increase the quantity taken up in 40min. The failure of folate metabolism in vitamin B(12) deficiency can be satisfactorily explained if l-methionine similarly affects the membrane transport of naturally occurring folates. 7. Further details of the results have been deposited as Supplementary Publication SUP 50028 (4 pages) at the British Library (Lending Division), (formerly the National Lending Library for Science and Technology), Boston Spa, Yorks. LS23 7BQ, U.K., from whom copies may be obtained on the terms given in Biochem. J. (1973) 131, 5. PMID- 4155291 TI - Effect of glucagon on phenylalanine metabolism and phenylalanine-degrading enzymes in the rat. AB - Glucagon administered subcutaneously to rats for 10 days had no significant effect on liver phenylalanine hydroxylase activity, but induced liver dihydropteridine reductase more than twofold. In rats administered a phenylalanine load orally, glucagon treatment stimulated oxidation and depressed urinary phenylalanine excretion. These responses could not be related to an effect of glucagon on hepatic tyrosine-alpha-oxoglutarate aminotransferase activity. Even in rats with phenylalanine hydroxylase activity depressed to 50% of control values by p-chlorophenylalanine administration, glucagon treatment increased the phenylalanine-oxidation rate substantially. Although hepatic phenylalanine-pyruvate aminotransferase was increased tenfold in glucagon-treated rats, glucagon treatment did not increase urinary excretion of phenylalanine transamination products by rats given a phenylalanine load. Glucagon treatment did not affect phenylalanine uptake by the gut or liver, or the liver content of phenylalanine hydroxylase cofactor. It is suggested that dihydropteridine reductase is the rate-limiting enzyme in phenylalanine degradation in the rat, and that glucagon may regulate the rate of oxidative phenylalanine metabolism in vivo by promoting indirectly the maintenance of the phenylalanine hydroxylase cofactor in its active, reduced state. PMID- 4155292 TI - The effect of lysine on gluconeogenesis from lactate in rat hepatocytes. AB - 1. In freshly prepared isolated rat liver cells there is a lag in gluconeogenesis from lactate. The magnitude of the lag increases with increasing lactate concentration. 2. The lag is virtually abolished by lysine. 3. A few other amino acids (tyrosine, arginine, asparagine, ornithine) and NH(4)Cl had effects similar to, but less pronounced than, lysine during the early stage of incubation. Lysine was unique in accelerating gluconeogenesis beyond the lag period. 4. The effects of the accelerators are not additive. 5. Glycine, serine, threonine, cysteine, tryptophan and histidine at 2mm markedly inhibit (>20%) gluconeogenesis from lactate. 6. Oleate, which promotes gluconeogenesis from lactate by supplying acetyl-CoA required for the pyruvate carboxylase reaction, had no effect on the lag, yet oleate oxidation showed no lag. 7. Preincubation of cells decreased the lag and decreased the magnitude of the lysine effect. 8. Pyruvate (added at 1mm to give an initial [lactate]/[pyruvate] ratio of 10) also abolished the lag and decreased the lysine effect by about 50%. 9. Lysine reversed the inhibition by ethanol of gluconeogenesis from lactate. 10. All accelerators increased the rate of re-oxidation of cytosolic NADH as shown by a rapid re-adjustment of the [lactate]/[pyruvate] ratio on addition of 10mm-lactate. 11. The accelerated rates of gluconeogenesis are associated with an increased formation of aspartate and glutamate and especially alanine. 12. The existence of the lag period can be explained on the basis of the fact that the accumulation of pyruvate during the lag diverts oxaloacetate from gluconeogenesis to malate formation, i.e. that the re-oxidation of cytosolic NADH takes precedence over gluconeogenesis. This means that much oxaloacetate formed by the pyruvate carboxylase reaction has to be transferred twice from the mitochondria to the cytosol by the aspartate shuttle. Under these conditions the operation of the shuttle limits the rate of gluconeogenesis from lactate. Lysine and other accelerators may increase the effectiveness of the shuttle by providing components of the aspartate aminotransferases involved. The question of why lysine specifically accelerates gluconeogenesis beyond the lag period is discussed. PMID- 4155293 TI - Hormonal regulation of adipose-tissue acetyl-Coenzyme A carboxylase by changes in the polymeric state of the enzyme. The role of long-chain fatty acyl-Coenzyme A thioesters and citrate. AB - 1. Acetyl-CoA carboxylase activity was measured in extracts of rat epididymal fat pads either on preparation of the extracts (initial activity) or after incubation of the extracts with citrate (total activity). In the presence of glucose or fructose, brief exposure of pads to insulin increased the initial activity of acetyl-CoA carboxylase; no increase occurred in the absence of substrate. Adrenaline in the presence of glucose and insulin decreased the initial activity. None of these treatments led to a substantial change in the total activity of acetyl-CoA carboxylase. A large decrease in the initial activity of acetyl-CoA carboxylase also occurred with fat-pads obtained from rats that had been starved for 36h although the total activity was little changed by this treatment. 2. Conditions of high-speed centrifugation were found which appear to permit the separation of the polymeric and protomeric forms of the enzyme in fat-pad extracts. After the exposure of the fat-pads to insulin (in the presence of glucose), the proportion of the enzyme in the polymeric form was increased, whereas exposure to adrenaline (in the presence of glucose and insulin) led to a decrease in enzyme activity. 3. These changes are consistent with a role of citrate (as activator) or fatty acyl-CoA thioesters (as inhibitors) in the regulation of the enzyme by insulin and adrenaline; no evidence that the effects of these hormones involve phosphorylation or dephosphorylation of the enzyme could be found. 4. Changes in the whole tissue concentration of citrate and fatty acyl-CoA thioesters were compared with changes in the initial activity of acetyl CoA carboxylase under a variety of conditions of incubation. No correlation between the citrate concentration and the initial enzyme activity was evident under any condition studied. Except in fat-pads which were exposed to insulin there was little inverse correlation between the concentration in the tissue of fatty acyl-CoA thioesters and the initial activity of acetyl-CoA carboxylase. 5. It is suggested that changes in the concentration of free fatty acyl-CoA thioesters (which may not be reflected in whole tissue concentrations of these metabolites) may be important in the regulation of the activity of acetyl-CoA carboxylase. The possibility is discussed that the concentration of free fatty acyl-CoA thioesters may be controlled by binding to a specific protein with properties similar to albumin. PMID- 4155295 TI - Purification and characterization of guanylate cyclase from Caulobacter crescentus. PMID- 4155296 TI - Comparative studies of NADP-malic enzyme from C-4 and C-3 plants. PMID- 4155294 TI - Regulation of guanylate cyclase in guinea-pig islets of Langerhans. AB - 1. Guanylate cyclase activity was determined in homogenates of guinea-pig islets of Langerhans by measurement of the conversion of [alpha-(32)P]GTP into cyclic [(32)P]GMP, the reaction products being separated on columns of neutral alumina. 2. The pH optimum of the enzyme was 7.3; it showed a requirement for bivalent cations, the effectiveness of the cations tested being Mn(2+)>>Ca(2+)>Mg(2+). 3. About 70% of enzyme activity was sedimented by centrifugation at 105000g for 60min; activity was increased 2.3-fold by treatment of homogenates with 0.1% Triton X-100. 4. Guanylate cyclase activity of homogenates was increased by acetylcholine, secretin or pancreozymin, but was inhibited by adrenaline, noradrenaline or ATP. Insulin, glucagon, prostaglandins E(1) or E(2), glucose, F( ), diazoxide or glibenclamide were ineffective. 5. Determination of cyclic GMP amounts in islets by radioimmunoassay showed a basal concentration of 2.0pmol/mg of protein, which was increased by incubation of the islets in the presence of acetylcholine or the phosphodiesterase inhibitor 3-isobutyl-1-methylxanthine, but was unaffected by glucose. 6. Dibutyryl cyclic GMP had significant stimulatory effects on rates of insulin biosynthesis in isolated rat islets of Langerhans. 7. These results suggest a possible role for cyclic GMP in the regulation of insulin biosynthesis and secretion. PMID- 4155297 TI - Ethanol and drug metabolism in mouse liver microsomes subsequent to lipid peroxidation-induced destruction of cytochrome P-450. PMID- 4155298 TI - Mitochondrial ATP-Pi exchange complex. PMID- 4155299 TI - Effect of glycyrrhetinic acid on the cyclic nucleotide system of the rat stomach. PMID- 4155300 TI - Stimulation of drug metabolism by ascorbic acid in weanling guinea-pigs. PMID- 4155301 TI - Inhibition of hepatic mixed function oxidase activity by propyl gallate. PMID- 4155302 TI - Mediation of reduced nicotinamide adenine dinucleotide phosphate dependent reduction of cytochrome c by morphine. PMID- 4155303 TI - Myocardial adenine nucleotides, hexose phosphates and inorganic phosphate, and the regulation of phosphofructokinase activity during fluoroacetate poisoning in the rat. PMID- 4155304 TI - Effect of trimetoquinol on the cyclic AMP level in the tracheal muscle of guinea pig. PMID- 4155305 TI - Reduced glucagon induction of tyrosine aminotransferase in perfused livers after ethanol treatment. PMID- 4155306 TI - A direct test for mono-oxygenase activity of intact small intestine using surface reflectance fluorimetry. PMID- 4155307 TI - [The relation between the crystalline structure and biological activity of molecules of the di- and tripropyl acetates]. PMID- 4155308 TI - Nitroreduction of 5-nitrofuran derivatives by rat liver xanthine oxidase and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase. PMID- 4155309 TI - Ontogenesis of choline acetyltransferase, tyrosine hydroxylase, monoamine oxidase and catechol-O-methyl transferase in the superior cervical ganglion of swine. PMID- 4155310 TI - Azotomycin--toxicologic, biochemical and pharmacologic studies in mice. PMID- 4155311 TI - The effects of amiodarone (L 3428), an alpha and beta receptor antagonist, on overflow of transmitter and uptake of noradrenaline in the cat spleen. PMID- 4155312 TI - Controlled clinical trials and caries prevention. PMID- 4155313 TI - Caries experience in english children and young adults during the years 1947 1972. PMID- 4155314 TI - Rampant dental caries in 5-year-old children from a fluoride and from a non fluoride community. PMID- 4155315 TI - Dental caries: the distinction between delay and prevention. PMID- 4155316 TI - Effect of a new beta-adrenergic blocking agent, ICI 66o82, on exercise haemodynamics and airway resistance in angina pectoris. PMID- 4155317 TI - Management of bronchospasm. PMID- 4155318 TI - Immunology of malignancy. Papers presented at the Symposium held at the Charles Salt Research Centre, the Robert Jones and Agnes Hung Orthopaedic Hospital, Oswestry, Shropshire, England 26-28 March 1973. PMID- 4155319 TI - Leucocyte separation and transfusion. PMID- 4155320 TI - The cellular origin of bioluminescence in the colonial hydroid Obelia. PMID- 4155321 TI - [Electron transfer in the membranes of the endoplasmic reticulum; the participation of cytochrome b5 in the NADPH oxidation reactions]. PMID- 4155323 TI - [Role of hydrophobic interactions in electron transfer in rat liver microsomes]. PMID- 4155322 TI - [Properties of the Na+, K+-ATPase from the cerebral cortex of the rat]. PMID- 4155324 TI - [Alpha-adrenoreactive structures of the intracranial vessels and their importance in regulation of the blood circulation of the brain]. PMID- 4155325 TI - Abolition of the allogeneic inhibition of hematopoietic stem cells by means of syngeneic lymphocytes. PMID- 4155326 TI - Psychometric patterns as predictors of outcome following hip surgery. PMID- 4155327 TI - Proceedings: Histamine receptors in the cardiovascular system of the cat. PMID- 4155328 TI - Proceedings: NMR studies of the binding of substrate analogues to L. casei dihydrofolate reductase. PMID- 4155329 TI - Proceedings: Some observations on electrically-inexcitable cells (neuroglia?) in rat sympathetic ganglia. PMID- 4155330 TI - Proceedings: Evaluation of iontophoretic N-methylbicuculline and other inhibitory amino-acid antagonists in rat brain stem. PMID- 4155331 TI - Proceedings: Pharmacological studies on single neurones in the substantia nigra of the rat. PMID- 4155332 TI - Proceedings: Assessment of the agonist and antagonist activities of narcotic analgesic drugs by means of the mouse vas deferens. PMID- 4155333 TI - Proceedings: Modification of the antinociceptive activity of narcotic agonists and antagonists by intraventricular injection of biogenic amines in mice. PMID- 4155334 TI - The effects of a new beta-adrenoceptor blocking compound, tolamolol, on haemo dynamics and myocardial function in man. AB - 1 The effects of tolamolol on haemodynamics and myocardial contractility were investigated in two groups of six patients undergoing diagnostic cardiac catheterization.2 The intravenous administration of tolamolol (0.15 mg/kg) produced a significant fall in heart rate from a control value (87 +/- 7 to 62 +/ 3 beats/min) 5 min after administration and a concomitant fall in cardiac output from 4.7 +/- 0.9 to 3.5 +/- 0.8 litres/minute. There was no significant change in systemic blood pressure, pulmonary artery blood pressure or stroke volume.3 There was no change in left ventricular end diastolic pressure after tolamolol. There was a fall in the maximum rate of rise of the left ventricular pressure (LV dp/dt(max)) and the derived index of the left ventricular contractile state (V(max)).4 These results suggest that tolamolol has a predominantly negative chronotropic but also a lesser negative inotropic action on the heart. PMID- 4155335 TI - Role of endogenous catecholamines in the anti-inflammatory activity of alpha adrenoceptor blocking agents. AB - 1 Drugs which release or modify the response to catecholamines were examined for their effect on the permeability of the mouse peritoneal vascular bed to circulating plasma albumin, labelled with Evans blue.2 Phenoxybenzamine, phentolamine, piperoxane, yohimbine or cocaine reduced the extravasation of Evans blue into the peritoneum, an effect which was antagonized by beta-adrenoceptor blocking drugs. The inhibitory effect of desipramine on the extravasation of Evans blue was less completely antagonized by beta-adrenoceptor blockade.3 Inhibition of catecholamine biosynthesis, ganglion blockade or adrenergic neurone blockade antagonized the reduction in dye extravasation by alpha-adrenoceptor blocking agents and cocaine, but had no significant effect on the response to desipramine. The inhibitory effects of alpha-adrenoceptor blocking agents on dye extravasation were not prevented by bilateral adrenalectomy.4 Mice subjected to the procedure for estimation of vascular permeability excreted increased amounts of adrenaline and noradrenaline. Pretreatment with phenoxybenzamine, piperoxane or cocaine further increased catecholamine excretion, but desipramine caused only a small increase in catecholamine excretion which did not correlate with its effect on dye extravasation.5 It is suggested that phenoxybenzamine, phentolamine, piperoxane and cocaine reduce vascular permeability in the mouse peritoneum by releasing and/or potentiating the effects of endogenous catecholamines on beta-adrenoceptors. Endogenous catecholamines do not appear to be involved in the anti-inflammatory activity of desipramine. PMID- 4155336 TI - The haemodynamic effects of prolonged oral administration of oxyfedrine, a partial agonist at beta-adrenoceptors: comparison with propranolol. AB - 1 Haemodynamic changes have been studied in cats after the chronic oral administration of oxyfedrine (14 mg/kg for 3-4 weeks) or of placebo (lactose). The initial part of the study was carried out under double-blind conditions. The arterial blood pressure was between 19 mmHg (diastolic) and 27 mmHg (systolic) higher in the oxyfedrine treated animals, but there were no differences between the two groups with regard to cardiac output, left ventricular dP/dt max, heart rate or systolic ejection time.2 In cats similarly treated with propranolol (4 mg/kg) there was a slight (12%), but significant, reduction in cardiac output.3 Isoprenaline dose-response curves were shifted to the right in the cats administered oxyfedrine as well as in those administered propranolol. The degree of shift was five-fold (positive chronotropic response) and 20-fold (decrease in diastolic blood pressure) in the oxyfedrine group and 10- and 80-fold, respectively, in the propranolol group.4 In contrast to the partial blockade of the effects of isoprenaline, the haemodynamic response to oxyfedrine was largely unaltered, both in the cats pretreated with propranolol and in those pretreated with oxyfedrine. The pressor response to noradrenaline was potentiated in the cats pretreated with oxyfedrine.5 These results provide an explanation for the anti-anginal action of oxyfedrine. Some degree of beta-adrenoceptor blockade is achieved without a reduction in cardiac output or left ventricular dP/dt max. The relevance of these findings to the haemodynamic situation in angina is discussed. PMID- 4155337 TI - Effects of Gymnodinium breve toxin on the smooth muscle preparation of guinea-pig ileum. AB - 1 The effects of Gymnodinium breve neurotoxin (GT) on smooth muscles were studied using the guinea-pig isolated ileum.2 The toxin caused strong spasmogenic effects at 1-4 mug/ml, characterized by prolonged tonic contraction with superimposed pronounced pendular movements. Tachyphylaxis was observed upon administration of successive doses.3 Atropine blocked the contractile response elicited by GT, whereas mepyramine and hexamethonium failed to do so. These findings tentatively suggested a cholinergic involvement at a post-ganglionic site of action.4 In the presence of tetrodotoxin the effects of GT were abolished, excluding direct action of the toxin on the smooth muscle.5 It is concluded that GT exerts its spasmogenic effects through stimulation of the post-ganglionic cholinergic nerve fibres. PMID- 4155338 TI - Editorial: Bone marrow transplants in leukemia. PMID- 4155339 TI - A memorable decade in the history of neurology 1874-84. I. PMID- 4155340 TI - Letter: Lorazepam poisoning. PMID- 4155341 TI - Letter: Prevention of exercise-induced asthma by indoramin. PMID- 4155342 TI - Tyrosine hydroxylase inhibition by cycloheximide and anisomycin is not responsible for their amnesic effect. PMID- 4155343 TI - Neurotransmitter synthesis in cephalopod retina. PMID- 4155345 TI - [Present and new therapy in cardiology]. PMID- 4155344 TI - [Comparative double-blind clinical trial of SB 5833 and temazapam]. PMID- 4155347 TI - Trimethylamine oxide reduction by Salmonella. PMID- 4155346 TI - Biosynthesis of branched long-chain fatty acids by species of Bacillus: relative activity of three alpha-keto acid substrates and factors affecting chain length. PMID- 4155348 TI - Polyarteritis nodosa complicated by a multiple sclerosis like syndrome. AB - A case is presented of a 16-year-old boy with angiographically proven polyarteritis nodosa who developed a multiple sclerosis like syndrome affecting the brain stem and cerebrum. His serum demyelinated nerve in tissue culture. The case is reviewed in detail and the mechanism of myelotoxicity is discussed. PMID- 4155349 TI - Monthly intermittent chemotherapy of chronic schizophrenic outpatients with pipothiazine palmitate. PMID- 4155350 TI - The clinical pharmacology of commonly used antihypertensive drugs. PMID- 4155351 TI - Choice of antihypertensive drugs for the treatment of hypertension, including hypertensive emergencies. PMID- 4155352 TI - Current concepts in the drug management of angina pectoris. PMID- 4155354 TI - [Conclusions of the conference on acute abdominal conditions in gynecology and pregnancy]. PMID- 4155353 TI - A cytofluorometric study of the myenteric plexus in the guinea pig. PMID- 4155356 TI - Population dynamics and age grading of mosquitos. AB - The dynamics of a vector population follows a characteristic pattern determined by the normal or modified environmental conditions of the biotope and by vector behaviour. The wide use of the precise method of age grading developed by Detinova and Polovodova has led to the conclusion that the dynamics of the various age groups may indicate behavioural, environmental, and epidemiological trends and changes and their significance. Age grading is useful for the qualitative assessment of vector density in general and of man-mosquito contact from the operational and epidemiological points of view, but only when sampling in time and space and the processing of the material collected have been correctly performed. PMID- 4155355 TI - Assessment of causal prophylactic activity in Plasmodium berghei yoelii and its value for the development of new antimalarial drugs. AB - The causal prophylactic activity of several reference and experimental antimalarial compounds was assessed in sporozoite-induced infections of NMRI mice with Plasmodium berghei yoelii (strain 17X). The animals were inoculated with 10 000 sporozoites per mouse and treated once 2-4 hours later. The test system has proved to be very suitable in experiments involving more than 3 000 mice. The infection rate in 448 untreated controls was 97.3%. Lowering the sporozoite content of the inoculum to 1 000 or 100 sporozoites markedly reduced the rate (65.1% and 32.7%). In experiments with primaquine the causal prophylactic activity was also influenced by the time of drug administration before or after sporozoite inoculation. No causal prophylactic effect was demonstrable with quinine, chloroquine, amodiaquine, amopyroquine, RC-12, or B 505. Primaquine was active, but pamaquine and pentaquine were only sporadically active. The pre erythrocytic stages of P. b. yoelii were only slightly sensitive to dapsone, sulfadiazine, and sulformethoxine; they were 10-100 times more susceptible to proguanil, cycloguanil, and pyrimethamine. The experimental 6-aminoquinolines NI 147/36, NI 187/82, and BA 138/111 and the 7-chlorolincomycin derivative U 24729 were also studied. Experiments in which curative activity against blood-induced infections of P. b. yoelii was evaluated showed that the causal prophylactics act more specifically against the pre-erythrocytic than against the erythrocytic forms. This specificity was most pronounced among the DHFR-inhibitors, whose outstanding activity may be explained by the fact that the rate of multiplication of the pre-erythrocytic forms of P. b. yoelii is greater than that of other plasmodia used hitherto; it is also greater than the rate shown by the malaria parasites of man and that of the erythrocytic forms of P. b. yoelii itself. We believe that this feature will render P. b. yoelii very useful for determination of the causal prophylactic activity of new compounds, but it may also overrate the potency of drugs that interfere with nucleic acid biosynthesis. PMID- 4155357 TI - Allied health personnel in anesthesia. PMID- 4155358 TI - Structure, function, and possible origin of a bifunctional allosteric enzyme, Escherichia coli aspartokinase I-homoserine dehydrogenase I. PMID- 4155359 TI - Psychiatric aspects of learning disabilities. PMID- 4155360 TI - [Characteristics of molluscan tissue respiration]. PMID- 4155361 TI - [Testosterone in the peripheral blood of sheep with natural and experimental cryptorchism before and after suppression of adrenal cortical function]. PMID- 4155362 TI - [NADP- and NAD-malate dehydrogenase in the liver and renal cortex in rats and hormonal regulation of their activity]. PMID- 4155363 TI - Control of fatty-acid biosynthesis by long-chain acyl CoAs and by lipid membranes. PMID- 4155364 TI - The synthesis of adenine-substituted derivatives of NADP and their potential as active coenzymes and affinity adsorbents. PMID- 4155365 TI - Effect of temperature on the transmitter release from the "purinergic" nerves in the guinea-pig taenia coli. PMID- 4155366 TI - Prediction of the non-specific cardiodepressant effects of beta-adrenoceptor blocking agents in vitro and in vivo by means of the Hansch analysis. PMID- 4155367 TI - Coenzyme dependency of alcohol dehydrogenase in the retina of the rat. III. Effect of light-and dark adaptation on the redox state of the pyridine nucleotides. PMID- 4155368 TI - Coenzyme dependency of alcohol dehydrogenase in the retina of the rat. IV. Retinol dehydrogenase (RDH) activity in the developing normal and retinitis rat retina, and the effect on enzyme activity of increasing concentrations of NAD or NADP. PMID- 4155369 TI - Effects of glutamate and GABA on specific response properties of neurones in the visual cortex. PMID- 4155370 TI - The differential sensitivity of spinal interneurones and Renshaw cells to Kainate and N-methyl-D-aspartate. PMID- 4155371 TI - The umbrellar growth process in the leptomedusae Phialidium hemisphaericum (syn. Campanularia johnstoni). PMID- 4155372 TI - Effect of burimamide and metiamide on pentagastrin-stimulated gastric acid secretion and gastric mucosal blood flow in cats. PMID- 4155373 TI - A soluble transhydrogenase enzyme from Rhodospirillum rubrum chromatophores. PMID- 4155374 TI - Kinetic isotope effects in the NAD- and NADP-specific isocitrate dehydrogenases of pig heart. PMID- 4155375 TI - Protochlorophyll and protochlorophyllide as precursors for chlorophyll synthesis in vitro. PMID- 4155376 TI - [Activities of a health center feldsher in the control of eye injuries in industry]. PMID- 4155377 TI - [Feldsher Alexander Stepanovich Vasil'chuk]. PMID- 4155378 TI - The effects of artificial cryptorchidism on the composition of epididymal plasma in the rabbit. PMID- 4155380 TI - Regional graft-versus-host and host-versus-graft reactions: histology of the popliteal lymph nodes. PMID- 4155379 TI - [Some regulatory mechanisms of intraosseous hemodynamics]. PMID- 4155381 TI - Protein turnover in rat testis. PMID- 4155382 TI - Sulthiame and behaviour. PMID- 4155383 TI - The employee health service and infection control. PMID- 4155384 TI - Settle plate assessment of airborne infections. PMID- 4155385 TI - Sanitation codes help curb food poisoning. PMID- 4155386 TI - The impact of institutionalization. PMID- 4155387 TI - [Editorial: A new report with old ideas]. PMID- 4155388 TI - A Canadian patient's bill of rights. PMID- 4155389 TI - Enzymes of carbohydrate and fat metabolism in anti-insulin serum diabetes; inactivation by free fatty acids and the protective effect of cellular protein. PMID- 4155390 TI - Analysis of lymphoid cell types developing in mouse foetal liver. PMID- 4155391 TI - Studies of metabolism in embryonic development. V. Biosynthesis of corticosteroids by trout embryos. PMID- 4155392 TI - Oxidative enzymes in the development of Fasciola hepatica L. I. Tetrazolium reductases and oxidases in miracidium. PMID- 4155393 TI - [Effects of repeated administration of ephedrine and pre-treatment with syrosingopine on the sympathetic ganglia]. PMID- 4155394 TI - [Effects of an adrenergic beta-receptor blockader, 2-acetyl-7-(2-hydroxy-3 isopropylamino) propoxybenzofuran hydrochloride on the cardiovascular system]. PMID- 4155395 TI - [Electroencephalographic study of 5-(o-chlorphenyl)-1-methyl-7-nitro-1, 3-dihydro 2H-1, 4-benzodiazepine-2-one (ID-690)]. PMID- 4155396 TI - Penicillium viridicatum mycotoxicosis in the rat. IV. Attempts to modify the tissue responses. PMID- 4155397 TI - The determination of methyprylon and its metabolites in biological fluids by gas chromatography. PMID- 4155398 TI - The clinical spectrum of prune belly syndrome. PMID- 4155399 TI - Prune belly syndrome with gastrointestinal tract anomalies. PMID- 4155400 TI - Halogenated hydrocarbon solvents: long term effects and biological sampling in human beings. International conference, Hamburg, October 24-26,1973. Conclusions and recommendations. PMID- 4155401 TI - The control of dental disease by prevention. PMID- 4155402 TI - Current experiments in the delivery of dental services. PMID- 4155403 TI - Behavioral approaches for problems with alcohol. PMID- 4155404 TI - Psychological and social variables and personality patterns of drug abusers. PMID- 4155405 TI - Amphetamines in the District of Columbia. III. Stimulant abuse in narcotics addicts in treatment, with an emphasis on phenmetrazine. PMID- 4155406 TI - Naloxone and the narcotic abuser: a controlled study of partial blockade. PMID- 4155407 TI - [What is secured in the therapy of chronic inflammatory colonic diseases?]. PMID- 4155408 TI - Vesical distension and ureteral activity in the canine. PMID- 4155409 TI - Proceedings: Human erythrocyte glucose 6-phosphate dehydrogenase. Content of tightly bound NADP. PMID- 4155410 TI - [Letter: Exchangebility of penicillin preparations in penicillin allergy]. PMID- 4155411 TI - [Use of beta receptor blockaders in psychiatry]. PMID- 4155413 TI - Proceedings: Chronic granulomatous disease. PMID- 4155412 TI - The role of circulating hepatitis B antigen/antibody immune complexes in the pathogenesis of vascular and hepatic manifestations in polyarteritis nodosa. AB - To investigate further the role of hepatitis B antigen (HBs Ag) and specific immune complexes in polyarteritis, sera from 55 histologically confirmed cases were tested for the presence of hepatitis B antigen-associated particles and hepatitis B-antibody (anti HBs) by solid phase radio-immunoassay, electron microscopy, and passive haemagglutination. Results of these findings have been correlated with the clinical course of the disease.HBs Ag was detected in 30 patients (54.5%) and anti HBs in 13/45 (28%). Subtyping in 20 patients revealed that 11 were Y and 9 D. Thirty-seven cases (69%) demonstrated either HBs Ag or anti HBs and 5/45 (11%) had both. Electron microscopic examination showed 20 nm spherical and tubular particles in sera of 20/27 patients with 42 nm particles in 11 cases and clumped particles in 12 (60%). No correlation was found between detection of immune complexes and liver disease whereas the presence of coexisting hepatitis B antigen and antibody or aggregated particles was restricted to cases of active vasculitis. Seroconversion or the presence of hepatitis B antibody alone was associated with improved prognosis. Circulating hepatitis B antigen antibody complexes may be responsible for vasculitis or polyarteritis but do not appear to be pathogenic for the liver. PMID- 4155414 TI - A mosquito egg counter by simple modification of a colorimeter. PMID- 4155415 TI - The personal and marital adjustment of parents as related to observed child deviance and parenting behaviors. PMID- 4155416 TI - Psychopharmacology in the aged. Use of psychotropic drugs in geriatric patients. PMID- 4155417 TI - Psychopharmacology in the aged. Research considerations in geriatric psychopharmacology. PMID- 4155418 TI - Psychopharmacology in the aged. Discussion. PMID- 4155419 TI - Current leprosy research: a report on the 10th Internation Leprosy Congress. PMID- 4155420 TI - Proceedings: Effect of age on steroidogenesis in experimental bilateral cryptorchid rats. PMID- 4155421 TI - Proceedings: A proposed model of the neurotransmitters involved in the control of corticotrophin releasing hormone. PMID- 4155422 TI - Proceedings: Clinical and hormonal effect of human chorionic gonadotrophin in prepubertal crytorchid boys. PMID- 4155423 TI - Proceedings: The mechanism of hypertriglyceridaemia in oestrogen-treated rats. PMID- 4155424 TI - Identification and tooth morphology. PMID- 4155425 TI - [Treatment of pollinoses. Results of 3 years of allergology consultations]. PMID- 4155426 TI - Changes in intracellular free calcium concentration during illumination of invertebrate photoreceptors. Detection with aequorin. AB - Aequorin, which luminesces in the presence of calcium, was injected into photoreceptor cells of Limulus ventral eye. A bright light stimulus elicited a large increase in aequorin luminescence, the aequorin response, indicating a rise of intracellular calcium ion concentration, Ca(i). The aequorin response reached a maximum after the peak of the electrical response of the photoreceptor, decayed during a prolonged stimulus, and returned to an undetectable level in the dark. Reduction of Ca(o) reduced the amplitude of the aequorin response by a factor no greater than 3. Raising Ca(o) increased the amplitude of the aequorin response. The aequorin response became smaller when membrane voltage was clamped to successively more positive values. These results indicate that the stimulus induced rise of Ca(i) may be due in part to a light-induced influx of Ca and in part to release of Ca from an intracellular store. Our findings are consistent with the hypothesis that a rise in Ca(i) is a step in the sequence of events underlying light-adaptation in Limulus ventral photoreceptors. Aequorin was also injected into photoreceptors of Balanus. The aequorin responses were similar to those recorded from Limulus cells in all but two ways: (a) A large sustained aequorin luminescence was measured during a prolonged stimulus, and (b) removal of extracellular calcium reduced the aequorin response to an undetectable level. PMID- 4155428 TI - Muscle transplantation and regeneration in the dystrophic hamster. Part 2. Histochemical studies. PMID- 4155427 TI - Diagnostic accuracy of clinical data, quantitative electromyography and histochemistry in neuromuscular disease. A study of 105 cases. PMID- 4155429 TI - The group supervisory conference. PMID- 4155430 TI - Computer-assisted learning in graduate psychiatric nursing. PMID- 4155432 TI - CAMP: computer and me: psychotherapeutically. PMID- 4155431 TI - The disadvantaged student in nursing education. PMID- 4155433 TI - Experiential learning in groups. PMID- 4155434 TI - Collegiate nursing education: an ambivalent professionalism. PMID- 4155435 TI - A brief bibliography on fatigue and fitness. PMID- 4155436 TI - Countercurrent immunoelectrophoresis in the evaluation of childhood infections. AB - Samples of CSF, serum, and urine from 162 children with a clinical diagnosis of possible bacterial infection were examined by CIE within 1 hr of admission to the hospital. Results obtained were compared to information derived from gram stain and bacterial cultures of these specimens. Thirty-eight of 59 patients with culturally proved bacterial infections had positive CIE determinations at the time of admission. Highest correlation between culture and CIE results was in patients with meningitis due to Hemophilus influenzae type b while poorest correlation was obtained in children with pneumococcal septicemia. PRP within serum or CSF was quantitated on 21 occasions in patients with H. influenzae meningitis. Patients who experienced sequelae of their meningitis had significantly (p less than 0.005-0.025) higher levels of PRP within CSF and serum than those whose recovery was uneventful. PMID- 4155437 TI - Mycobacterium fortuitum osteomyelitis of the calcaneus secondary to a puncture wound. PMID- 4155438 TI - Hepatic microsomal drug oxidation and electron transport in newborn infants. AB - Many drugs require oxidative metabolism for termination of action and/or for elimination from the body. Many oxidative reactions are catalyzed by hepatic microsomal enzymes. The activities of various drug-metabolizing enzymes, namely, NADPH cytochrome c reductase, NADPH oxidase, aminopyrine-N-demethylase, and analine P-hydroxylase, and the content of cytochrome P-450, were measured in hepatic microsomes obtained from seven newborn infants and four adult patients. The results in the newborn infant show increasing activities of these enzymes (except aminopyrine-N-demethylase) related to advancing age. Good correlation between three components of the hepatic microsomal mixed function oxidase system and aniline p-hydroxylase was established, whereas only NADPH oxidation correlated with aminopyrine N-demethylation. The rate of substrate or drug oxidation and the activities of the components of the microsomal electron transport pathway were lower than comparable values in the adult. The data demonstrate a possible biochemical basis for the transient deficiency in drug metabolism seen in newborn infants. PMID- 4155439 TI - Item content of the Group Personality Projective Test. PMID- 4155440 TI - "Short-form" content scales for the MMPI. PMID- 4155441 TI - Proceedings: Aequorin-light and tension responses from bundles of myofibrils following a sudden change in free calcium. PMID- 4155442 TI - Psychological potentials of chronic pain. PMID- 4155443 TI - The effects of population density on the overt behavior of mental patients. PMID- 4155444 TI - Manifest hostility as modified by the K and SO-R scales of the MMPI. PMID- 4155445 TI - Correlation of placebo responses and personality characteristics in myofascial pain-dysfunction (MPD) patients. PMID- 4155446 TI - [Angiographic aspects of periarteritis nodosa. Apropos of 1 case]. PMID- 4155447 TI - Investigation of the cellular immunocompetence in chronic lymphatic leukemia and malignant lymphoma patients as assessed by the local graft versus host reaction in rats. PMID- 4155448 TI - [Complications associated with iodine contrast media in urinary tract exploration. Current views of the radiologist]. PMID- 4155449 TI - [Circulatory changes caused by a beta blocker. 1. Y-6124(Adobiol)]. PMID- 4155450 TI - [Fluroxene toxicity in mice]. PMID- 4155451 TI - [Discussion: The current methods of management of hypertension and strokes- impressions at the WHO Hypertension and Stroke Meeting held in Tpkyo]. PMID- 4155452 TI - [Treatment of digitalis-induced arrhythmia]. PMID- 4155453 TI - [The influence of catecholamines and synthetic derivatives of vasopressin on the active transport of sodium ions and other bioelectrical properties of the cell membrane (author's transl)]. PMID- 4155454 TI - [Study of the pulmonary vasoactive substances--with special reference to action mechanism of prostaglandins F2a and E1]. PMID- 4155455 TI - [Contributions of the general meeting of the Japan Nursing Association]. PMID- 4155456 TI - [Role of the adrenergic mechanisms in the action of drugs on the cardiovascular system]. PMID- 4155457 TI - [Qualification of patients with angina pectoris for beta-adrenolytic drug treatment]. PMID- 4155458 TI - [Histamine and histidine metabolism in ischemic heart disease]. PMID- 4155459 TI - [Clinical and EEG course observations in postvaccinal encephalitis with fatal outcome]. PMID- 4155460 TI - [Treatment of bronchial asthma]. PMID- 4155461 TI - [Treatment of patients with chronic pneumonia]. PMID- 4155463 TI - [Return from Hawaii; seminar on population problems]. PMID- 4155462 TI - [Use of beta-adrenostimulators in patients with bronchial asthma]. PMID- 4155464 TI - Age-dependent induction of isoenzymes of tyrosine aminotransferase of the liver of the rat. PMID- 4155465 TI - Rosette forming cells in neonatal animals. PMID- 4155466 TI - [Effect of bronchitis in the aged on serum gamma glutamyl transpeptidase activity]. PMID- 4155469 TI - Purification of a plasma membrane-bound adenosine triphosphatase from plant roots. PMID- 4155470 TI - Cultured cell systems and methods for neurobiology. PMID- 4155471 TI - Solubilization and polyacrylamide gel electrophoresis of membrane enzymes with detergents. PMID- 4155472 TI - Biogenesis and modulation of membrane properties in greening Chlamydomonas reinhardi, y-1 cells. PMID- 4155473 TI - Drugs for cardiac complaints--part 2. PMID- 4155474 TI - [Molecular nitrogen fixation by propionic acid bacteria]. PMID- 4155475 TI - [Effect of cultivation conditions on the aminotransferase activity of wine yeast]. PMID- 4155476 TI - [Effect of the antibiotic xanthotricin on the respiratory chain of Candida lipolytica]. PMID- 4155478 TI - Letter: Tetracycline-resistant pneumococci. PMID- 4155477 TI - Amino acid neurotransmitters and the brain. Beattie Smith lecture, March 28, 1974. PMID- 4155480 TI - [Clinical and morphological aspects of acute renal hypertension in panarteritis nodosa (author's transl)]. PMID- 4155479 TI - [Successes and failures of immunosuppressive therapy in nephropathies]. PMID- 4155481 TI - [Psychiatric treatment and care in occupational rehabilitation (author's transl)]. PMID- 4155482 TI - Association of Operating Room Nurses Congress 1974. PMID- 4155483 TI - Acid base balance in relation to gastric acid secretion stimulated by histamine and pentagastrin in cats. PMID- 4155484 TI - The effect of histamine-H2-receptor-antagonists on gastric acid secretion, gastric mucosal blood flow and acid base balance in cats. PMID- 4155485 TI - An analysis of the alpha- and beta-effects of isoprenaline on the isolated nictitating membraen. PMID- 4155486 TI - Macrophages activation during graft-versus-host reaction. PMID- 4155487 TI - The action of bicuculline upon acetylcholine-induced excitations of central neurones. PMID- 4155488 TI - To practice or not to practice: developing state law and policy on physician assistants. PMID- 4155489 TI - [76th Congress of the Italian Society of Surgery: "Current states of the universities and hospitals]. PMID- 4155490 TI - [Meeting on hydrologic studies in San Pellegrino spas]. PMID- 4155491 TI - [Preparation with the flurazepam base. Study on tolerance and efficacy]. PMID- 4155492 TI - [Utilization of aides in ophthalmology]. PMID- 4155493 TI - [Opening address at the occasion of the 1st Austrian Nursing Congress; from September 7-9, 1974 in Graz]. PMID- 4155494 TI - [Letter: Allergic reactions to penicillin]. PMID- 4155495 TI - [The conditioning of patients for the purpose of bone marrow transplantation. Recent results]. PMID- 4155496 TI - [Effect of dextran, ganglioplegic agents and alpha receptor blocking agents on experimental hemorrhagic shock]. PMID- 4155497 TI - [Necrosis of small intestine as a consequence of periateritis nodosa]. PMID- 4155498 TI - Psychological management of Crohn's disease. PMID- 4155499 TI - [Current status in clinical bonemarrow-transplantation (author's transl)]. PMID- 4155501 TI - Catalysis, binding and enzyme-substrate complementarity. PMID- 4155500 TI - The lymphocyte surface. III. Function of Fc receptor, C'3 receptor and surface Ig bearing lymphocytes: identification of a radioresistant B cell. PMID- 4155502 TI - Leishmania in phlebotomid sandflies. I. Modifications of the flagellum associated with attachment to the mid-gut and oesophageal valve of the sandfly. PMID- 4155503 TI - The synaptic organization of optic afferents in the amphibian tectum. PMID- 4155504 TI - Functional synaptic relations during the development of the retino-tectal projection in amphibians. PMID- 4155505 TI - Pigment epithelial cell ensheathment of cone outer segments in the retina of the domestic cat. PMID- 4155506 TI - [Polarographic determination of temazepam. 14. Drug analysis by means of polarography or oscillopolarography]. PMID- 4155507 TI - Determination of drug-induced changes in sleep quality based on digital computer "sleep prints". PMID- 4155508 TI - Evolution and adaptive radiation in the macrothricidae (Crustacea: Cladocera): a study in comparative functional morphology and ecology. PMID- 4155510 TI - [Present-day education is--comprehensive education]. PMID- 4155509 TI - Control of pain by drugs. PMID- 4155511 TI - [Importance of the sterilization of flora in intrabronchial secretion during treatment and prevention of exacerbations of chronic bronchitis]. PMID- 4155512 TI - [Bacteriological diagnosis of chronic bronchitis and its therapeutical importance]. PMID- 4155513 TI - Note on treatment of heterosexual anxiety using short-term massed desensitization. PMID- 4155514 TI - Comparative parental MMPI protocols of children evaluated at a child development clinic. PMID- 4155515 TI - Facilitation of group desensitization of test anxiety. PMID- 4155517 TI - Contrasting assumptions and directions in MMPI research on alcoholism. PMID- 4155516 TI - Physical fitness and personality in alcoholism. Canonical analysis of measures before and after treatment. PMID- 4155518 TI - The hormones of the hypothalamus. PMID- 4155519 TI - Intracranial injection of neurotransmitters and hormones and feeding in sheep. PMID- 4155520 TI - Pavlovian conditioned inhibitory processes in behavior therapy. PMID- 4155521 TI - An assessment of oral disease among primary school children in Lebanon. 1. Assessment of dental caries. PMID- 4155522 TI - [Evaluation of the new therapy in the treatment of shock. Use of the beta adrenergic metaproterenol]. PMID- 4155523 TI - [Adrenergic blockade theory on the bronchial asthma, especially emphasizing adenyl cyclase activity (author's transl)]. PMID- 4155524 TI - [Sleep: recent physiological acquisitions and clinical and pharmacological perspectives]. PMID- 4155525 TI - [The 1st hours of acute coronary insufficiency. Clinical diagnosis and 1st emergency measures]. PMID- 4155526 TI - [Medical treatment of myocardial infarct in the acute phase]. PMID- 4155527 TI - [Liver involvement in progressive scleroderma]. PMID- 4155528 TI - [Enzyme tests in the biochemical exploration of liver function]. PMID- 4155529 TI - [Enzymograms of secondary liver cancer]. PMID- 4155530 TI - [Trial of multifactorial discriminant analysis in the diagnosis of medical, surgical or neoplastic icterus]. PMID- 4155531 TI - Scientific aspects of behavior therapy. PMID- 4155532 TI - Perspective on flooding. PMID- 4155533 TI - Behavioral methods in group and family therapy. PMID- 4155534 TI - Biofeedback and visceral learning: clinical applications. PMID- 4155535 TI - Research and training needs in behavior therapy. PMID- 4155536 TI - Phobias: broad-spectrum behavioral views. PMID- 4155537 TI - Toward hypotheses for a biochemical component in the vulnerability to schizophrenia. PMID- 4155538 TI - The effects of certain pharmacological compounds and ions on fish hearts. PMID- 4155539 TI - [Physician's assistant or nurse]. PMID- 4155541 TI - [Bronchial asthma in children. II. Prevention by medication]. PMID- 4155540 TI - [Hypnotics]. PMID- 4155542 TI - [Sequelae of tooth and jaw injuries in children]. PMID- 4155543 TI - Anaphylactic shock clinical forms, pathogenesis and treatment. PMID- 4155544 TI - [Preventive health care policy. Opening contribution in the panel discussion on the physicians' meeting in Odense, September 13th, 1974]. PMID- 4155545 TI - [Preventive health care policy. Panel debate on the physicians' meeting in Odense September 13th 1974]. PMID- 4155546 TI - [Drug information. New drugs. Ritodrine (Utopar, Philips-Duphar/Ferrosan)]. PMID- 4155550 TI - [Gynecomastia and cryptorchism]. PMID- 4155547 TI - [Immunological problems in renal transplants]. PMID- 4155551 TI - [Determination of sensitivity of the sputum microflora to antibiotics during treatment of pneumonia]. PMID- 4155552 TI - [Epidemiologic-sociological problems in the continuing control of cardiovascular diseases. Paper presented at the 2d Congress for Sociology and the socio-medical conference of the Society for Social Hygiene of the GDR]. PMID- 4155553 TI - [Enzyme excretion in the urine in hyperthyroidism]. PMID- 4155554 TI - [Manifestation of myotonic disturbances of muscle function under continuous intravenous drip treatment with the beta-adrenergic th 1165 a (fenoterolhydrobromide) (author's transl)]. PMID- 4155555 TI - [Construct conceptions in the empirical personality research and personality diagnosis]. PMID- 4155556 TI - [The mechanism of eye movements]. PMID- 4155557 TI - [Role of graphic and semantic-syntactic factors in reading. A neuro psycholinguistic study]. PMID- 4155558 TI - [Methodical theoretical-diagnostic analysis of psychophysiological personality variables]. PMID- 4155559 TI - [Proceedings: Introduction to the theme "surgical treatment of degenerative diseases of the spine" at the Orthopedic Congress at Aachen]. PMID- 4155560 TI - [Proceedings: Traumatic origin or a secondary calcaneus]. PMID- 4155561 TI - [Value of sanation of the biliary tract in the complex pathogenetic therapy of allergic dermatitis in children]. PMID- 4155562 TI - [New Soviet preparation of pyrroxan in the treatment of patients with allergic dermatoses]. PMID- 4155563 TI - [Effect of radiation therapy on NAD-H2- and NADPH-H2-dehydrogenase and lactate dehydrogenase histochemistry in cancerous tumors of the human larynx]. PMID- 4155564 TI - [Possible and actual trends in the evolution of invertebrates]. PMID- 4155565 TI - [A caries index of therapeutic value]. PMID- 4155566 TI - [Scid proteinase and phosphatase activity of the blood serum in patients with osteoarthritis deformans]. PMID- 4155567 TI - [Status and developmental perspectives on surgical care of the population of Narynsk oblast]. PMID- 4155568 TI - [Our 1st experience with a mitral valve prosthesis]. PMID- 4155569 TI - [Effects of a magnetic field on blood viscosity and coagulation activity]. PMID- 4155570 TI - [Effect of the stability of magnetic fields on the acitvity of hyaluronidase and the structure of hyaluronic acie]. PMID- 4155571 TI - [Significance of gastroscopic study in the early disgnosis of stomach pathology]. PMID- 4155572 TI - [Electrophoretic picture of proteins in the duodenal contents cholecystitis in children]. PMID- 4155573 TI - [Effect of some preparations excreted by Stachys betonicaeflora Rupr. on the contractile activity of the uterus]. PMID- 4155574 TI - [Dynamics of the clinical symptoms of diseases in patients with stage IIA hypertension under the effects of balneotherapy in the mountain enviroment health resort "Cholpon-Ata" in the foothills of Frunze]. PMID- 4155576 TI - [Level of various trace elements in the water of the river Ak-Bury and the underground waters of its basin]. PMID- 4155575 TI - [The Kirghiz State Medical Institute in its jubilee year]. PMID- 4155577 TI - [Use of some indices of external respiration in the evaluation of work adaptation of miners under conditions of the foothill climate of Kirghizia]. PMID- 4155578 TI - [Stomatological status of various gruops of students in Frunze]. PMID- 4155579 TI - [Problems of organization of health care for children with rheumatic heart disease under specialized pioneer camp conditions in Kirghizia]. PMID- 4155580 TI - E1General surgical intervention in patients with pulmonary tuberculosis. PMID- 4155581 TI - [Activity of ceruloplasmin and carboanhydrase, iron transferrin saturation of blood plasma of women with normally proceeding pregnancies; labor and the puerperium]. PMID- 4155582 TI - [Retropharyngeal abscess in children]. PMID- 4155583 TI - [The Kirghizia Health Service and prospects of its development]. PMID- 4155584 TI - [Medical care in terminal states]. PMID- 4155585 TI - [Tasks of paramedical personnel in chemical industry]. PMID- 4155586 TI - Recent advances in cardiovascular pharmacology. PMID- 4155587 TI - [Effects of psychotropic drugs on the epithelium of rat mammary gland, uterus, uterine glands and adrenal cortex]. PMID- 4155588 TI - Chemical sensitivity at different temperatures of the Br-type, bimodal pace-maker neurone in the CNS of the snail Helix pomatia l. PMID- 4155589 TI - Organization of visual cortex primary response. PMID- 4155590 TI - Suppresion by bivalent cations of the recycling system composed of glucose-6 phosphate dehydrogenase and glutathione reductase. PMID- 4155591 TI - Child health in the People's Republic of China. PMID- 4155592 TI - Differentiation of H1- and H2-receptors mediating positive chrono- and inotropic responses to histamine on atrial preparations of the guinea-pig. PMID- 4155593 TI - Cardiovascular effects of burimamide and metiamide. PMID- 4155594 TI - The pharmacology of azatadine, a potential antiallergy drug. PMID- 4155595 TI - [Studies on the ocular circulation with an ultrasonic Doppler technique. Diagnosis and classification of Takayasu's disease]. PMID- 4155596 TI - Metabolism of the bloodmeal in tsetse flies (a review). PMID- 4155597 TI - The African attitude toward sickness. Its relation to sculpture. PMID- 4155598 TI - Autoimmunity in trypanosome infections. III. The antiglobulin (Coombs) test. PMID- 4155599 TI - Autoimmunity in trypanosome infections. IV. Natural infections in hartebeest, hyaena and lion in the Serengeti National Park, Tanzania. PMID- 4155600 TI - Lack of incorporation of tritiated thymidine in Trypanosoma vivax in vitro. PMID- 4155601 TI - Hydatid disease in India. PMID- 4155602 TI - Metabolism of drugs by microorganisms in the intestine. PMID- 4155603 TI - Principles of immunity. II. Cellular immunology and immunogenetics. PMID- 4155604 TI - [Biochemical anomalies in blood cells in refractory anemia]. PMID- 4155605 TI - [Antibacterial effect of rifampicin and its chemotherapeutic properties in experiments on animals]. PMID- 4155606 TI - [Action of the antibiotic xanthothricin on Ehrlich ascites tumor cells]. PMID- 4155607 TI - The pattern of flight muscle damage in relation to the distribution of developing filarial larvae in Aedes aegypti and Mansonia uniformis. PMID- 4155608 TI - Arbovirus infections in Sarawak, October 1968--February 1970: Japanese encephalitis virus isolations from mosquitoes. PMID- 4155609 TI - Autonomic drug-receptor interaction in the presence and absence of extracellular calcium in mammalian myocardium. PMID- 4155610 TI - Modifications of the pressor response to hog renin by adrenalectomy, demedullation, adrenoceptor blocking drugs and catecholamine depletors in anaesthetized rats. PMID- 4155611 TI - [Analgesic properties of narcotic antagonists]. PMID- 4155612 TI - Gamma-glutamyl transpeptidase activity (GGTP) in ontogenetic development of the guinea pig. PMID- 4155613 TI - Purification and some properties of gamma-glutamyl transpeptidase from cow's milk. PMID- 4155614 TI - Localization of gamma-glutamyl transpeptidase (GGTP) in the rat small intestine. Adaptive response of the enzyme after massive small bowel resection. PMID- 4155615 TI - Vanadium in whole human enamel and its relationship to dental caries. PMID- 4155616 TI - Sucrose taste thresholds in caries-free naval recruits. PMID- 4155617 TI - A 15-yr retrospective survey of the distributions of clinical caries attacks in human permanent maxillary incisors. PMID- 4155618 TI - [Localization of (3H)gamma-aminobutyric acid in the cochlea. Light and electron microscopic autoradiography (author's transl)]. PMID- 4155619 TI - The responses of the human temporal and rabbit ear artery to 5-hydroxytryptamine and some of its antagonists. PMID- 4155620 TI - The epidemiology of self-poisoning in Hobart, 1968-1972. PMID- 4155621 TI - I. Synchrony and desynchrony in fear and avoidance. PMID- 4155622 TI - II. Desynchrony in measures of fear. PMID- 4155623 TI - Effect of nitrate on the synthesis and decay of nitrate reductase of Neurospora. AB - 1. A method was developed to examine the turnover of nitrate reductase by the use of tungstate. 2. Evidence is presented which suggests that the disappearance of nitrate reductase activity from Neurospora mycelia exposed to non-inducing conditions is due to the disappearance of the enzyme protein(s) from the mycelia, and not merely due to the disappearance of its (their) catalytic power. 3. The presence of NO(3) (-) in the culture medium slows down the rate of degradation of nitrate reductase in Neurospora in vivo. PMID- 4155624 TI - The effect of starvation on insulin secretion and glucose metabolism in mouse pancreatic islets. AB - 1. Rates of insulin secretion, glucose utilization, lactate output, incorporation of glucose into glycogen, contents of glucose 6-phosphate, fructose 1,6 diphosphate and ATP, and maximally extractable enzyme activities of hexokinase, high-K(m) glucose-phosphorylating activity (;glucokinase'), glucose 6-phosphatase and unspecific acid phosphatase were measured in isolated pancreatic islets from fed and 48-h-starved mice. 2. In the fed state insulin secretion from isolated islets was increased five- to six-fold when the extracellular glucose concentration was raised from 2.5mm to 16.7mm; 5mm-caffeine potentiated this effect. The secretory response to glucose of islets from mice starved for 48h was diminished at all glucose concentrations from 2.5mm up to approx. 40mm. Very high glucose concentrations (60mm and above) restored the secretory response to that found in the fed state, suggesting that the K(m) value for the overall secretory process had been increased (approx. fourfold) by starvation. Addition of 5mm caffeine to islets from starved mice also restored the insulin secretory response to 2.5-16.7mm-glucose to normal values. 3. Extractable hexokinase, ;glucokinase', glucose 6-phosphatase and unspecific phosphatase activities were not changed by starvation. 4. Glucose utilization and glycolysis (measured as the rate of formation of (3)H(2)O from [5-(3)H]glucose over a 2h period) was decreased in islets from starved mice at all glucose concentrations up to approx. 55mm. At still higher glucose concentrations up to approx. 100mm, there was no difference between the fed and starved state, suggesting that the K(m) value for the rate limiting glucose phosphorylation had been increased (approx. twofold) by starvation. Preparation of islets omitting substrates (glucose, pyruvate, fumarate and glutamate) from the medium during collagenase treatment lowered the glucose utilization measured subsequently at 16.7mm-glucose by 38 and 30% in islets from fed and starved mice respectively. Also the 2h lactate output by the islets at 16.7mm extracellular glucose was diminished by starvation. Incorporation of glucose into glycogen was extremely low, but the rate of incorporation was more than doubled by starvation. 5. After incubation for 30min at 16.7mm-glucose the content of glucose 6-phosphate was unchanged by starvation, that of ATP was increased and the concentration of (fructose 1,6-diphosphate plus triose phosphates) was decreased. 6. Possible mechanisms behind the correlated impairment in insulin secretion and islet glucose metabolism during starvation are discussed. PMID- 4155627 TI - The synthesis of naturally occurrring phosphonolipids. PMID- 4155625 TI - Changes in phylloquinone epoxidase activity related to prothrombin synthesis and microsomal clotting activity in the rat. AB - The oxidation of phylloquinone to the 2,3-epoxide (by phylloquinone epoxidase) was studied in liver from control and warfarin-resistant rats. The reaction requires microsomal fraction, soluble protein, a heat-stable soluble factor and O(2). It is not inhibited by CO or CN(-). Epoxidase activity was stimulated if plasma prothrombin was lowered either by anticoagulants or the absence of vitamin K. The activity of the enzyme rapidly returned to normal values after the administration of vitamin K to hypoprothrombinaemic rats. These differences in the activity of the enzyme occur in the microsomal fraction and not the cytosol. A thrombin-generating polypeptide that accumulates in microsomal fraction of hypothrombinaemic rats correlated directly with epoxidase activity. These data support the view that enzymic interconversion of phylloquinone and its 2,3 epoxide participates in the biological activity of vitamin K. PMID- 4155626 TI - Diurnal rhythms of hepatic carbohydrate metabolism during development of the rat. AB - The ;8+16' feeding schedule (8h feeding and 16h without food in each 24h cycle) was applied to nursing mother rats to study enzyme development in neonatal rats in the absence of solid food. A ;16+8' suckling schedule (16h with the mother and 8h while the mother is fed in a separate cage) was used to show that the increases in pyruvate kinase, glucokinase and aldolase B activities that occur in the late suckling period of liver development do not require the intake of solid food at this time. Their activities may, however, be modulated by the composition of the diet at the time of weaning. Adaptation to the composition of the diet can occur within one feeding period, and to the periodicity of food provision in one or two feeding periods. In the early neonatal period, diurnal rhythms of tyrosine aminotransferase, liver glycogen and glucokinase are either greatly suppressed or absent, but develop rapidly after weaning. Food-dependent rhythms of glycogen and tyrosine aminotransferase were included in the late suckling period (day 14). PMID- 4155628 TI - Regulatory mechanisms for liver acetyl coenzyme A carboxylase. PMID- 4155629 TI - Neuronally mediated enzyme induction in adrenergic neurons and adrenal chromaffin cells. PMID- 4155630 TI - Metabolic regulation in the release and action of excitatory and inhibitory amino acids in the central nervous system. PMID- 4155631 TI - Regulatory significance of the release and action of adenine derivatives in cerebral systems. PMID- 4155632 TI - Beta-adrenoreceptor blocking properties of new thienylethanolamine derivatives. PMID- 4155633 TI - Cardiovascular and antiarrhythmic effects of 1-(4,5-dichloro-2-thienyl)-2-t butylaminoethanol (QM-5119), a new beta-adrenergic blocking agent. PMID- 4155634 TI - Effect of camazepam (SB-5833), a new antianxious drug, on cardiac contractility and coronary hemodynamics. PMID- 4155635 TI - Prolongation of anoxia-induced hyperemia in healthy middle-aged men treated with cinnarizine and flunarizine. PMID- 4155637 TI - [Influence of bromazepam and of diazepam on the acute toxicity and ECG changes caused by nicotine in guinea pigs]. PMID- 4155636 TI - [Pharmacokinetics of bromazepam in man]. PMID- 4155638 TI - [Influence of bromazepam on the subacute toxicity and ECG changes caused by nicotine in guinea pigs]. PMID- 4155639 TI - The prevalence of dental caries in 3-year-old children. Some social differences and a method of assessing pre-school needs at a local level. PMID- 4155640 TI - Adult dental health in Scotland 1972. PMID- 4155641 TI - Personality characteristics of adolescent amphetamine users as measured by the MMPI. PMID- 4155642 TI - Personality and demographic characteristics of two sub-types of drug abusers. PMID- 4155643 TI - Combination of carcinoembryonic antigen and gamma glutamyl transpeptidase in the study of the evolution of colorectal cancer. AB - Plasma CEA values and serum gamma glutamyl transpeptidase activities have been compared in control subjects and 109 patients with colorectal carcinoma and 35 with non-malignant hepatic disease. CEA values alone differentiate hepatic metastases from non-malignant hepatic disease with a high degree of certainty. While CEA may be elevated with metastases, irrespective of site, gammaGT is elevated mainly in association with hepatic metastases. The combination of CEA and gammaGT is helpful in identifying hepatic metastases and in their differentiation from local recurrences or metastases to other sites. PMID- 4155644 TI - [Energy metabolism in Candida tropicalis. Oxidative phosphorylation in Candida tropicalis cultivated on alkanes]. PMID- 4155645 TI - [Modification of the enzymes of hepatic glutamine and glutamate metabolism following ammonium salts administration]. PMID- 4155646 TI - [The influence of the graft versus host reaction on the growth of syngenous sarcoma in mice]. PMID- 4155647 TI - [Ionization constants of several narcotic analgesics and their pain relieving activity]. PMID- 4155648 TI - [A histochemical study of several energy metabolism indices in the hearts of rats following acute fatigue]. PMID- 4155649 TI - [Participation of monoaminergic mechanisms of the rat hypothalamus in conditioned avoidance reactions]. PMID- 4155650 TI - Pharmacology of the aorta. A brief review. PMID- 4155651 TI - A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs. AB - 1 Injection of pentobarbitone sodium into a lateral cerebral ventricle of rats produced a loss of righting reflex. The duration of anaesthesia was dose dependent.2 The optimum dose of pentobarbitone to allow study of the factors affecting the sleeping time was considered to be 650 mug injected in 25 mul water.3 In a study of the effect of age and sex on the sleeping time, the youngest rats used (88 g body weight) were found to be the most sensitive to barbiturate. Female rats were more sensitive than male animals.4 The duration of anaesthesia was not affected by induction or inhibition of hepatic drug metabolizing enzyme activity.5 Prior administration (acute) of central nervous system depressant drugs shortened the latent period and prolonged the duration of sleep. Prior administration of stimulant drugs antagonized the effect of pentobarbitone.6 Animals withdrawn following chronic administration of a number of drugs, barbitone, barbitone/bemegride mixture, Mandrax (methaqualone: diphenhydramine; 10: 1), chlordiazepoxide, nitrazepam, chlorpromazine or ethanol, exhibited a significant tolerance to intracerebroventricularly administered pentobarbitone.7 Withdrawal of amphetamine, morphine, methyprylon or diazepam did not result in tolerance to intracerebroventricularly administered pentobarbitone.8 Chronic administration of all drugs except amphetamine and morphine induced a tolerance to intraperitoneally administered hexobarbitone (100 mg/kg).9 The usefulness of sleeping time determination following intracerebroventricular administration of pentobarbitone as an assessment of central nervous system excitability is discussed. It is concluded that this method gives a valid indication of the sensitivity of the central nervous system to barbiturate and of the level of excitability in general. The method is particularly applicable in situations where the activity of hepatic drug metabolizing enzyme activity may be altered. PMID- 4155652 TI - Analysis of the effects on body temperature of intracerebroventricular injection in anaesthetized dogs of gamma-aminobutyric acid. AB - 1 The cerebral ventricles of dogs under intravenous pentobarbitone sodium anaesthesia, were perfused with artificial cerebro-spinal fluid (CSF) at a rate of 0.4-0.5 ml/min from the ventricular to the aqueductal cannulae. The effluent was collected from the aqueductal cannula in 20 min samples. The animals' temperatures were recorded from the rectum.2 gamma-Aminobutyric acid (GABA) 0.1-5 mg when injected into the ventricles produced variable temperature effects. Doses of 0.1 and 0.5 mg always produced hyperthermia and 1 and 5 mg doses sometimes produced hyperthermia and sometimes hypothermia.3 Intraventricular perfusion with 2-bromolysergic acid diethylamide (BOL) and hyoscine did not block hyperthermia. Tests on the rat isolated stomach strip or the guinea-pig isolated superfused ileum for the possible release, respectively, of 5-hydroxytryptamine or acetylcholine by GABA were negative.4 When tested for the presence of prostaglandin E(PGE)-like substances on the isolated rat stomach strip, both the control effluent and the GABA effluent showed activity, the latter being much more potent. There was a temporal correlation between this effect and hyperthermia. Intraventricularly administered sodium salicylate converted the GABA-induced hyperthermia to hypothermia and blocked the release of PGE-like substances.5 Hypothermia induced by GABA alone or in the presence of sodium salicylate was associated with the release of noradrenaline into the effluent.6 Intraventricular administration of GABA in reserpinized dogs produced hyperthermia and not hypothermia. Similar results were obtained with phentolamine perfusion in normal dogs.7 Perfusion with calcium-free solution blocked both the noradrenaline-releasing and hypothermic actions of GABA.8 It is concluded that hyperthermia associated with intraventricular injections of GABA is due to the release of PGE-like substance and hypothermia is due to the release of noradrenaline. PMID- 4155653 TI - Inhibition by non-steroid anti-inflammatory agents of rabbit aorta contracting activity generated in blood by slow reacting substance C. AB - 1 A crude and a partially purified preparation of slow reacting substance C (SRS C) as well as arachidonic acid decreased resistance to perfusion of the dog hind paw. This effect was suppressed by treatment with non-steroid anti-inflammatory drugs.2 Injections of SRS-C or of arachidonic acid induced marked and reproducible contractions of strips of rabbit aorta and a rat stomach which were bathed in blood from an anaesthetized dog. The effect on the rabbit aorta is attributed to formation of a rabbit aorta contracting substance (RCS). The contractions were suppressed when the dog was treated with a non-steroid anti inflammatory drug.3 Incubation of blood or of platelet-rich plasma with SRS-C or arachidonic acid resulted in the formation of similar materials. This formation was suppressed by anti-inflammatory drugs.4 SRS-C, linoleic, linolenic, and arachidonic acids are suitable substrates for soybean lipoxidase for the generation of RCS.5 It is suggested that RCS and prostaglandin are formed within platelets, when SRS-C or arachidonic acid are injected into animals or added in vitro. Non-steroid anti-inflammatory drugs suppress these effects, possibly by inhibiting prostaglandin synthetase. PMID- 4155654 TI - [Determination of reduced and oxidized pyridine nucleotides in Clostridium pastorianum]. PMID- 4155655 TI - [Influence of the increased level of gamma-aminobutyric acid in the central nervous system on varios phases of the sleep-wakefulness cycle in rats]. PMID- 4155656 TI - Quinones as anticancer agents: potential bioreductive alkylating agents. PMID- 4155657 TI - [The effect of C cytochrome and NADP on energetic ratio as indicator of psychic disorders (author's transl)]. PMID- 4155658 TI - Malignant hypertension. PMID- 4155659 TI - Effect of autonomic blockade on the transient changes in cardiac frequency on relief of hypoxia in man. PMID- 4155660 TI - Methods of measuring the reliability of caries prevalence and incremental data. PMID- 4155661 TI - Prevalence and interrelationships of root surface caries on Lufa, Papua New Guinea. PMID- 4155662 TI - Social inequality and caries studies in 1,719 Danish military recruits. PMID- 4155663 TI - Evaluation of benapryzine in psychotic patients treated with phenothiazines. PMID- 4155664 TI - The treatment of arterial hypertension with a new alpha-blocker, indoramin. PMID- 4155665 TI - Assessment of lorazepam in severe neurotic states. PMID- 4155666 TI - Quantitative histochemistry of glucose metabolism in the islets of Langerhans. PMID- 4155667 TI - Studies on the metabolism of embryonic bone and its modification by parathyroid extract. PMID- 4155668 TI - Quantitative microscope-photometric determination of enzyme activities in cryostat sections. PMID- 4155669 TI - Some recent refinements of quantitative histochemical analysis. PMID- 4155670 TI - Biperiden (Akineton): effective prophylactic and therapeutic anti-parkinsonian agent. PMID- 4155671 TI - [Inactivation of allogeneic stem cells by lymphocytes identical as regards the H2 system of tissue compatibility]. PMID- 4155672 TI - [Content of tonic substances in seeds of Schizandra chinensis Baill]. PMID- 4155673 TI - The metabolism of safrole and 2',3'-epoxysafrole in the rat and guinea pig. PMID- 4155674 TI - In vitro acetylation of drugs by human blood cells. PMID- 4155675 TI - Tissue distribution and binding of radioactivity from 14C-thiourea in the rat. PMID- 4155676 TI - Quantitation of plasma levels of propoxyphene and norpropoxyphene by combined use of stable isotope labeling and selected ion monitoring. PMID- 4155677 TI - In vitro metabolism of 14C-pesticidal carbamates by fetal and maternal brain, liver, and placenta of the rat. PMID- 4155678 TI - Comparative stimulatory effects of four phenothiazines on hepatic microsomal enzymes. PMID- 4155679 TI - Partial resolution of the mixed-function oxidase system of bovine adrenocortical microsomes into two fractions in the absence of detergents. PMID- 4155680 TI - Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. PMID- 4155681 TI - [May the pertussis protective vaccination still be recommended?]. PMID- 4155682 TI - [Cytology of the kidney and urethra]. PMID- 4155683 TI - Studies on seed-oil triglycerides. Factors controlling the biosynthesis of fatty acids and acyl lipids in subcellular organelles of maturing Crambe abyssinica seeds. PMID- 4155684 TI - The reversible reduction of testosterone to androst-4-ene-3alpha, 17beta-diol by a soluble enzyme of rat liver. PMID- 4155685 TI - The flux of intermediates and products in aromatizaton of C19 steroids by human placental microsomes. PMID- 4155686 TI - Transfer of deuterium from (1-2H2) ethanol to Krebs cycle and related acids of rat liver in vivo. PMID- 4155687 TI - Synergism between lymph node and bone marrow cells for production of granulocytes. I. Requirement for immunocompetent cells. PMID- 4155688 TI - Synergism between lymph node and bone marrow cells for production of granulocytes. II. Enhanced colony-stimulating activity of sera of mice with graft versus-host reaction. PMID- 4155689 TI - [Feldsher's role in the control of eye injuries in the village]. PMID- 4155690 TI - [Feldsher Aleksandr Nikolaevich Grokhovskii]. PMID- 4155691 TI - Effect of metiamide on histamine metabolism in man. PMID- 4155693 TI - Effects of sympathetic denervation of the rabbit oviduct on normal ovum transport and on transport modified by estrogen and progesterone. PMID- 4155694 TI - [Prevention of dental caries by means of fluorina compounds. Scientific conference in Gracow, May 17, 1973]. PMID- 4155692 TI - Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease. AB - The faecal flora of 21 patients with proctocolitis and five patients with Crohn's disease of the large bowel was examined both while sulphasalazine was being administered and during control periods. Patients with proctocolitis and Crohn's disease who were not receiving sulphasalazine had a similar flora which did not differ in any way from the normal. The effect of sulphasalazine was to decrease the numbers of opalescent-negative clostridia, enterobacteria, and total non sporing anaerobes. It is suggested that this antibacterial effect of sulphasalazine, which has not been previously demonstrated, may be related to the beneficial effects of this drug in proctocolitis and should be investigated further. PMID- 4155695 TI - Virological investigations of mosquitoes in some biotopes of southern Moravia in summer season 1972. PMID- 4155696 TI - How to make your next conference count. PMID- 4155697 TI - Oxidation of exogenous NADH by corn mitochondria. PMID- 4155698 TI - Cyclophosphamide induced abnormalities of internal organs in rat foetuses. PMID- 4155699 TI - A case of hereditary methemoglobinemia with NADH-methemoglobin reductase (diaphorase) deficiency. PMID- 4155700 TI - Effect of environmental factors on thyroid gland in vitro. PMID- 4155701 TI - Social and psychological factors associated with length of stay in a drug treatment facility. PMID- 4155702 TI - Opiates, amphetamines, alcohol: a comparative study of American soldiers. PMID- 4155703 TI - Proceedings: Sites of gamma aminobutyrate transaminase (GABA-T) activity in the rat cerebellar cortex. PMID- 4155704 TI - A profile of non-specific arteritis as observed in Eastern India. PMID- 4155705 TI - The localization of enzymes in fixed sections of soybean root nodules by electron microscopy. PMID- 4155706 TI - Some correlates of Category Test scores for nonorganic psychiatric patients. PMID- 4155707 TI - The Goldberg rules in the detection of MMPI codebook modal diagnoses. PMID- 4155708 TI - Test-retest stability of long and short MMPI scales over two years. PMID- 4155709 TI - Discriminating criminal types and recidivism by means of the MMPI. PMID- 4155710 TI - The MMPI response consistencies of normal, neurotic and psychotic women. PMID- 4155711 TI - Depression as a function of levels of desired and obtained pleasure. PMID- 4155712 TI - Alcoholic personality types: identification and correlates. PMID- 4155713 TI - Minnesota Multiphasic Personality Inventory correlates of dysphasic language disturbances. PMID- 4155714 TI - The morphogenetic properties of the node in Clytia johnstoni. PMID- 4155715 TI - The effect of inhibitors on the electron-transport chain of Bacillus brevis. Evidence for branching of the NADH oxidase respiratory chain. PMID- 4155716 TI - Cytochromes in Streptococcus faecalis var. zymogenes grown in a haematin containing medium. PMID- 4155717 TI - Effects of D-glutamate on mycelial growth and glutamate dehydrogenase enzymes of Coprinus lagopus. PMID- 4155718 TI - Riboflavin deficiency and respiratory flavoproteins of Bacillus subtilis. PMID- 4155719 TI - Physiological and pharmacological properties of Purkinje cells in rat cerebellum degranulated by postnatal x-irradiation. PMID- 4155721 TI - A useful transformation for comparing dose-response curves. PMID- 4155720 TI - The role of cerebral blood flow for the recovery of the brain after prolonged ischemia. PMID- 4155722 TI - Competitive inhibition of Asp1-beta-amide-Val5-angiotensin II by Sar1-Ile5-Ile8 angiotensin II in cat isolated cardiac muscle and coronary vessels. PMID- 4155723 TI - Effect of neuroleptics on the disappearance rate of (14C) labelled catecholamines formed from (14C)tyrosine in mouse brain. PMID- 4155724 TI - Hypothermic and toxic actions of 2-butyne-1, 4-diol and other related diols in the rat. PMID- 4155725 TI - Inhibitory effect of L-glutamine on the aspirin-induced gastric lesions in the rat. PMID- 4155726 TI - Inhibition of alpha-chymotrypsin by dibenamine. PMID- 4155727 TI - Phase studies of mixed phosphated surfactants, n-hexane and water. PMID- 4155728 TI - A note on the interaction between two phosphated surfactants. PMID- 4155729 TI - Computer analysis of multicomponent ultraviolet spectra. PMID- 4155730 TI - A field test for hallucinogens: further improvements. PMID- 4155731 TI - Improved method for isolation of hypoglycins A and B from fruit of Blighia sapida. PMID- 4155732 TI - The binding of chlorpromazine to human serum albumin. PMID- 4155733 TI - Regulation of (3H)5-hydroxytryptamine release from rat brain slices. PMID- 4155734 TI - Influence of alpha- and beta-adrenoceptors on the release of noradrenaline from field stimulated atria and cerebral cortex slices. PMID- 4155735 TI - Increase in adrenal dopamine following 6-hydroxydopamine. PMID- 4155737 TI - The involvement of noradrenergic systems in the locomotor activity stimulation in mice produced by beta-phenethylamine. PMID- 4155736 TI - Enhancement of noradrenaline turnover in rat brain by L-dopa. PMID- 4155738 TI - The effects of indomethacin on the development of tolerance to amphetamine induced hyperthermia. Are prostaglandins involved? PMID- 4155739 TI - Inactivation of prostaglandin E2 by rabbit lung homogenates. PMID- 4155740 TI - Effects of a human plasma fraction on skin reactions in the rat and rabbit. PMID- 4155741 TI - Do adrenergic fibres have muscarinic inhibitory receptors?-- a reply. PMID- 4155742 TI - The choice of paper and thin-layer chromatographic systems for the analysis of basic drugs. PMID- 4155743 TI - Measurement of the 'spontaneity' of self-emulsifiable oils. PMID- 4155744 TI - Multicomponent analysis of ultraviolet spectra: application to pharmaceutical dosage forms. PMID- 4155745 TI - The depressant action of morphine on transmission at a skeletal neuromuscular junction is non-specific. PMID- 4155746 TI - Conditions affecting the interaction of cholinergic agents on the longitudinal muscle of the guinea-pig ileum--unexpected effects with hexamethonium. PMID- 4155747 TI - Glucose intolerance in thiamine-deficient rats. PMID- 4155748 TI - A pharmacokinetic investigation of the distribution and elimination of diethylpropion and its metabolites in man. PMID- 4155749 TI - Anthracene derivatives in tissue culture of Cassia senna L. PMID- 4155750 TI - Reversal of yeast-induced motor impairment in rats as a test for narcotic and non narcotic analgesics. PMID- 4155751 TI - Reversal by prostaglandin E2 of the inhibitory effect of indomethacin on contractions of guinea-pig ileum induced by angiotensin. PMID- 4155752 TI - Effect of isoprenaline on the phosphodiesterase activity of the rat heart. PMID- 4155753 TI - An isolated perfused coronary artery preparation from the kitten. PMID- 4155754 TI - The conformation of dopamine at its uptake site; further studies with rigid analogues. PMID- 4155755 TI - Effects of oxotremorine and physostigmine on the turnover of dopamine in the corpus striatum and the limbic system. PMID- 4155756 TI - Further evidence for the stimulation of rat brain dopamine receptors by a cyclic analogue of dopamine. PMID- 4155757 TI - Antagonistic effects of neuroleptics and apomorphine on synaptosomal tyrosine hydroxylase in vitro. PMID- 4155758 TI - Regional differences in homovanillic acid concentrations after acute and chronic administration of antipsychotic drugs. PMID- 4155759 TI - Distribution of amphetamine and its hydroxylated metabolites in various areas of the rat brain. PMID- 4155760 TI - Red back spider venom and inhibitory transmission. PMID- 4155761 TI - The effects of a human plasma fraction on adjuvant arthritis and granuloma pellet reactions in the rat. PMID- 4155762 TI - Pharmacokinetic studies on the selective beta1-receptor antagonist metoprolol in man. PMID- 4155763 TI - Electron-capture GLC determination of blood levels of 7-chloro-1,3-dihydro-5-(2' chlorophenyl)-2H-1,4-benzodiazepin-2-one in humans and its urinary excretion as lorazepam determined by differential pulse polarography. PMID- 4155764 TI - The effects of isoxsuprine hydrochloride on the cyclic nucleotide system in the rat uterus. PMID- 4155765 TI - Tryptaminergic and dopaminergic responses of Schistosoma mansoni. PMID- 4155766 TI - The internal anal sphincter in the cat: a study of nervous mechanisms affecting tone and reflex activity. AB - 1. Smooth muscle activities in rectum and internal anal sphincter have been recorded using intraluminal balloons.2. Reflex activation of the sphincter, caused by distension of the rectum, has been assessed before and after various combinations of blocking drugs.3. Responses to stimulation of hypogastric or sacral nerves, or to the administration of drugs with autonomic actions have been tested before and after various combinations of blocking drugs.4. Results indicate that the tone of the internal anal sphincter is influenced by a number of neural mechanisms. These include motor pathways involving both alpha adrenergic and cholinergic mechanisms and inhibitory pathways involving both beta adrenergic and non-adrenergic non-cholinergic mechanisms.5. Cholinergic contractions of the sphincter were converted to relaxations after alpha adrenergic blockade. This indicates that the contractions are an indirect effect operating through an adrenergic reflex. Cholinergic relaxations may also be indirect and operate through reflex inhibition secondary to rectal contractions.6. Sphincteric motor activity is controlled largely through alpha adrenergic mechanisms by adrenergic nerves acting directly on the muscle. beta Adrenergic inhibitory mechanisms are thought to operate indirectly via ganglia.7. The over-all control of the sphincter is by complex reflex mechanisms involving numerous pathways and the activity of the sphincter at any one time is determined by the net balance between motor and inhibitory influences.8. Sacral nerve stimulation indicated that it contains cholinergic nerves to the rectum, non adrenergic non-cholinergic inhibitory axons to the sphincter and variable numbers of adrenergic axons to the sphincter.9. Responses of the sphincter to drugs and nerve stimulation were often variable, as has been described many times in the literature. It is considered that this is due to complex combinations of indirect reflex effects, secondary to activation of structures outside the sphincter, operating with or against direct effects on the sphincter itself. PMID- 4155767 TI - Ionic mechanisms and receptor properties underlying the responses of molluscan neurones to 5-hydroxytryptamine. AB - 1. Molluscan neurones have been found to show six different types of response (three excitatory and three inhibitory) to the iontophoretic application of 5 hydroxytryptamine (5-HT). The pharmacological properties of the receptors and the ionic mechanisms associated with these responses have been analysed.2. Four of the responses to 5-HT (named A, A', B and C) are consequent upon an increase in membrane conductance whereas the other two (named alpha and beta) are caused by a decrease in membrane conductance.3. The A-response to 5-HT consists of a ;fast' depolarization due to an increase mainly in Na(+)-conductance; the A'-response is a ;slow' depolarization also associated with a Na(+)-conductance increase. Receptors mediating the A- and A'-depolarizations have different pharmacological properties and may exist side by side on the same neurone.4. Both the B- and C responses are inhibitory. The B-response is a ;slow' hyperpolarization due to an increase in K(+)-conductance, the C-response is a fast hyperpolarization associated with an increase in Cl(-)-conductance.5. The alpha-response to 5-HT is a depolarization which becomes reduced in amplitude with cell hyperpolarization and reverses at -75 mV; it is caused by a decrease in K(+)-conductance. The beta response is an hyperpolarization which increases in amplitude with cell hyperpolarization and reverses at -20/-30 mV. It results from a decrease in conductance to both Na(+) and K(+) ions.6. The receptors involved in the 5-HT responses associated with a conductance increase may be recognized by the action of specific antagonists: 7-methyltryptamine blocks only the A-receptors, 5 methoxygramine only the B-receptors and neostigmine only the C-receptors. Curare blocks the A- and C-receptors and bufotenine, the A-, A'- and B-receptors. No specific antagonists have yet been found for the 5-HT responses caused by a conductance decrease.7. The significance of the multiplicity of receptors is discussed. Their functional significance at synapses is analysed in the following paper. PMID- 4155769 TI - [Proceedings: Effects of 4-aminopyridine (4-AP) on the activity of the isolated giant nerve fiber of insects (Periplaneta americana)]. PMID- 4155768 TI - On the transmitter function of 5-hydroxytryptamine at excitatory and inhibitory monosynaptic junctions. AB - 1. Two symmetrical giant neurones located in the cerebral ganglion of Aplysia californica contain 4-6 p-mole 5-hydroxytryptamine (5-HT) and are able to synthesize it (Weinreich, McCaman, McCaman & Vaughn, 1973; Eisenstadt, Goldman, Kandel, Koike, Koester & Schwartz, 1973). Stimulation of each of these neurones evokes excitatory and inhibitory potentials in various cells of the ipsilateral buccal ganglion. In nine buccal neurones it evokes excitatory potentials, in other three, ;classical' inhibitory potentials and in one neurone an ;atypical' inhibitory potential.2. The connexion between the giant cerebral neurone and the cells receiving either an excitatory or a ;classical' inhibitory input from it are monosynaptic. TEA injection into the cerebral giant neurone, which prolongs the presynaptic spike, causes a gradual increase of both the excitatory and the inhibitory potentials. On the other hand, high Ca(2+) media, which block polysynaptic pathways, do not suppress these synaptic potentials.3. The iontophoretic application of 5-HT to the buccal neurones receiving excitatory input from the giant cerebral neurones evokes depolarizations showing the pharmacological properties of both A- and A'-responses to 5-HT (see preceding paper). Antagonists which block only the A-receptors (curare, 7-methyltryptamine, LSD 25) block partially the synaptic depolarizing potentials. Bufotenine, which blocks both the A- and A'-receptors, completely blocks the excitatory potentials. Thus, the post-synaptic membrane of these buccal neurones appears to be endowed with both A- and A'-receptors to 5-HT.4. The ;classical' inhibitory potentials elicited in three buccal neurones are hyperpolarizations which reverse at - 80 mV and are due to an increase in K(+)-conductance. The iontophoretic application of 5-HT to these post-synaptic neurones evokes hyperpolarizing B-responses which are also generated by an increase in K(+)-conductance. Antagonists which block the B responses (bufotenine, methoxygramine) also block the inhibitory potentials.5. The ;atypical' inhibitory potential evoked in one buccal neurone consists in an hyperpolarization which increases in amplitude with cell hyperpolarization. Iontophoretic application of 5-HT to this buccal cell evokes an hyperpolarizing beta-response which also increases in amplitude with cell polarization and results from a decrease in both Na(+)- and K(+)- conductances. The monosynaptic character of the ;atypical' inhibitory potential is not yet fully proven.6. It can be concluded that the excitatory and inhibitory synaptic effects evoked in the buccal neurones by the stimulation of the 5-HT-containing-giant cerebral neurones are very likely mediated by 5-HT. PMID- 4155770 TI - The practical and potential contributions of immunology to the problems of developing countries. PMID- 4155771 TI - [Receptors of steroid hormones: Corticoids]. PMID- 4155772 TI - [Determination of serum triglycerides by the initial speed method - a comparison between 2 methods utilizing oxidation-reduction processes involving NADH2]. PMID- 4155773 TI - [Enzyme activities in ascitic fluid and pleural effusion]. PMID- 4155774 TI - [Biochemical study of the amniotic fluid (2)]. PMID- 4155775 TI - [Drug interference in urinary 17-OHCS and 17-KS analyses]. PMID- 4155776 TI - [Relationship between the liver and gamma-glutamyl transpeptidase]. PMID- 4155777 TI - [Serum gamma-glutamyl transpeptidase isoenzyme in congenital biliary atresia]. PMID- 4155778 TI - [Gamma glutamyl transpeptidase activities in the serum and the wall of the bile capillaries of heavy drinkers]. PMID- 4155779 TI - [Gamma-glutamyl transpeptidase in the urine]. PMID- 4155780 TI - [Determination of urinary glutamyl transpeptidase - (3). Evaluation of the results of kidney function tests]. PMID- 4155781 TI - Early and delayed phases of hind paw edema in rats. PMID- 4155782 TI - [Experimental investigations on personality of glaucoma patients (author's transl)]. PMID- 4155783 TI - Coenzyme A and affinity chromatography. PMID- 4155784 TI - Use of pyridoxamine phosphate in affinity chromatography. PMID- 4155785 TI - Immobilized nucleotides for affinity chromatography. PMID- 4155786 TI - Purification of an enzyme containing a NADP-protected cysteine on organomercuri agarose 17beta-estradiol dehydrogenase. PMID- 4155787 TI - [Glucose catabolism enzymes and NAD-H2-oxidase in extracts of Bacillus anthracoides spores]. PMID- 4155788 TI - [Nitrate utilization by purple bacteria]. PMID- 4155789 TI - [The treatment of bronchiolar obstruction (author's transl)]. PMID- 4155790 TI - The effect of diazepam on spinal cord activities: possible sites and mechanisms of action. PMID- 4155791 TI - Comparison of the effects of clonidine on pre- and postsynaptic adrenoceptors in the rabbit pulmonary artery. Alpha-sympathomimetic inhibition of Neurogenic vasoconstriction. PMID- 4155793 TI - Micro-organisms from necrotic pulp of traumatized teeth. PMID- 4155792 TI - Effects of gamma-aminobutyric acid (GABA) and GABA antagonist drugs on ACTH release. PMID- 4155794 TI - Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. I) Protective activity against experimental neurogenic gastric ulcers and other pharmacologic properties. PMID- 4155795 TI - Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. II) Protective activity against drug-induced experimental ulcers. PMID- 4155796 TI - Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. III). Gastric antisecretory activity, antagonism against acid hypersecretion induced by pentagastrin and histamine, and other effects. PMID- 4155797 TI - Pharmacology of zolimidine (2-(p-methylsulfonylphenyl)-imidazo (1,2-a) pyridine) a new non-anticholinergic gastroprotective agent. IV) Enhancement of gastric mucus production in different experimental models. PMID- 4155798 TI - Financial management for school of nursing. Papers presented at the 1973-74 regional workshops sponsored by the Council of Diploma Programs held in Cincinnati, Chicago and New York. PMID- 4155799 TI - [Certain pharmacotherapeutic properties of heparin and its importance in complex treatment of tuberculosis (literature review)]. PMID- 4155800 TI - [Publicity in the area of psychiatry and neurology]. PMID- 4155801 TI - [Clinical and legal aspects of the prevention, recognition and assessment of neurogenic vaccination complications in childhood. 1. Clinical problems associated with the definition, recognition and prevention of vaccination complications in childhood]. PMID- 4155802 TI - GABA blockade, dopamine and schizophrenia: experimental studies in the cat. PMID- 4155803 TI - Antipsychotic drugs stimulate prolactin release. PMID- 4155804 TI - Dental caries in five year old schoolchildren. PMID- 4155805 TI - [Serum gamma-glutamyl-transpeptidase and urinary excretion of D-glucaric acid in epileptic patients treated with anticonvulsants]. PMID- 4155806 TI - [Dental caries extremes among groups of Danish schoolchildren]. PMID- 4155807 TI - [The incidence of dental caries in Greenland 1973-74]. PMID- 4155808 TI - [Fluoridation in Karl Marx Stadt. XII. Distribution of caries and dental rehabilitation in physically, mentally and emotionally handicapped children]. PMID- 4155809 TI - [7th World Congress in Cardiology; Buenos Aires, Argentina, September 1-7 1974]. PMID- 4155811 TI - [International symposium on apiculture]. PMID- 4155810 TI - A survey of congenital defects of sheep. PMID- 4155812 TI - [Role of Diplococcus in the etiology of mastitis]. PMID- 4155813 TI - Decayed, missing, and filled teeth among youths 12-17 years. PMID- 4155814 TI - A model of the vertebrate nervous system based largely on disinhibition: a key role of the GABA system. PMID- 4155815 TI - [The effect of gamma-aminobutyric acid on the liberation and metabolism of serotonin]. PMID- 4155816 TI - The role of astroglia as modulators of neuronal function in cerebral cortex: comparative data, and observations in vivo and in vitro in fluid, electrolyte and amino acid interrelationships. PMID- 4155817 TI - [Metabolism of glutamate and related amino acids in the brain]. PMID- 4155818 TI - [Amino acids in the brains of animals adapted to different living conditions]. PMID- 4155819 TI - [Alcohol and brain gamma-aminobutyric acid]. PMID- 4155820 TI - [Mechanisms of ammonia formation in the brain]. PMID- 4155821 TI - [Change in the enzymatic activity in the guinea pig myocardium on the administration of thyroxine and in thyroidectomy]. PMID- 4155822 TI - [Comparative characteristics of the activity of electron transport chain enzymes in injured and uninjured cerebral hemisphere tissue following unilateral cranio cerebral trauma]. PMID- 4155823 TI - [Gamma-aminobutyric acid concentration in the brains of animals infected with fixed rabies virus]. PMID- 4155824 TI - [The effect of vitamin A on rat liver phenylalanine-4-hydroxylase tyrosine transaminase activity]. PMID- 4155825 TI - [International Symposium on malaria in Rabat]. PMID- 4155826 TI - The medical assistant: an intermediate level of health care personnel. PMID- 4155828 TI - The medical assistant. Career status. PMID- 4155827 TI - The medical assistant: an intermediate level of health care personnel. Adress. PMID- 4155829 TI - The medical assistant. Acceptance, public and professional. PMID- 4155830 TI - The medical assistant. Assurance of quality, competence, and accountability. Accreditation. PMID- 4155831 TI - The medical assistant. Assurance of qulaity, competence, and accountability. Legal aspects. PMID- 4155832 TI - The medical assistant: an intermediate level of health care personnel. The principle obstacles and problems. PMID- 4155834 TI - The medical assistant: an intermediate level of health care personnel. The future prospect. PMID- 4155833 TI - The medical assistant: an intermediate level of health care personnel. Opening address. PMID- 4155835 TI - The medical assistant: an intermediate level of health care personnel. Purposes of the conference. PMID- 4155836 TI - Health services in the USA: trends in the education and training of health personnel. PMID- 4155837 TI - The medical assistant: an intermediate level of health care personnel. Defintion of terms. PMID- 4155838 TI - The medical assistant: an intermediate level of health care personnel. Discussion. PMID- 4155839 TI - Principal training programmes in the USA. Physician's assistant--physician's associate. PMID- 4155840 TI - Principal training programmes in the USA. MEDEX. PMID- 4155841 TI - The community health medic in Indian America. PMID- 4155842 TI - Medical assistants in the USA as viewed by the professions. The physician's view. PMID- 4155843 TI - Medical assistants in the USA as viewed by the professions. The nurse's view. PMID- 4155844 TI - Roles for the medical assistant. PMID- 4155845 TI - [Behavior of catecholamines and of cyclic 3'5'-AMP in plasma of normal persons under the effect of a beta-receptor blockader]. PMID- 4155846 TI - [Blood circulation in forearm in patients suffering from hyperkinetic heart syndrome following beta-stimulation and beta-block]. PMID- 4155847 TI - [Neurochemical mechanisms of septal influence on the conditioned avoidance reaction in rats]. PMID- 4155849 TI - [The influence of the frontal region on evoked potentials in the visual cortex of dogs]. PMID- 4155848 TI - [The effect of pharmacologic substances on the sequelae of emotional excitation in cats]. PMID- 4155850 TI - [Studies of natural foci of Tahyna virus in Southern Germany (author's transl) (author's transl)]. PMID- 4155851 TI - [On Polyomavirus inhibitors. II. In vivo experiments (author's transl)]. PMID- 4155852 TI - Leucocidic substances for Aeromonas hydrophila. PMID- 4155853 TI - [Cytochrome absorption spectra of bacteria as aid for solving taxonomic problems. 3rd report: The cytochrome absorption spectra of the investigated bacterial strains and their relationships to the taxonomy (author's transl)]. PMID- 4155854 TI - Serological studies of Leptospiras by immunodiffusion. PMID- 4155855 TI - [Standardizing in sero-diagnostic leptospirose investigations (author's transl)]. PMID- 4155856 TI - Pathogenicity of Leptospires of various serological types for some species of wild rodents. PMID- 4155857 TI - Effect of amino acids on the growth and phospholipid composition of some pathogenic fungi. PMID- 4155858 TI - [Studies of the diagnostic and prognostic potential of immynological tests for echinococcosis]. PMID- 4155859 TI - [On the quantitative rate of the immunoglobulins G, A, M, and D, of hemagglutination inhibiting antibodies, of transferrin, coeruloplasmin, alpha2 macroglobulin, and CRP in children with influenza A2/Hong Kong (author's transl)]. PMID- 4155860 TI - [Occurrence of antibody against Corona virus (OC 43) in the healthy population and in patients with a disease of the respiratory tract (author's transl)]. PMID- 4155861 TI - [Laboratory procedures in adenoviruses. I. Qualitative and quantitative immunofluorescence (author's transl)]. PMID- 4155862 TI - Classification of Micrococcaceae isolated from clinical sources. PMID- 4155863 TI - On the significance of L antigens for the serology, immunology and pathogenicity of Escherichia species. PMID- 4155864 TI - Purification and some properties of a heat-labile enterotoxin from escherichia coli. PMID- 4155865 TI - [Possible use of pyocins against Pseudomonas aeruginosa (author's transl)]. PMID- 4155866 TI - Morphological, cultural and biochemical characteristics of so called NAG vibrios isolated from human faeces and vomitus. Preliminary report. PMID- 4155867 TI - [Synthetic medium for testing of susceptibility. I. Susceptibility of bacteria to antibiotics and chemotherapeutic agents (author's transl)]. PMID- 4155868 TI - R-factor-induced resistance levels. PMID- 4155869 TI - Thermoresistant antigen in leptospires. Possibility of a macroscopic diagnosis of leptospirosis with a single antigen. PMID- 4155870 TI - Prevalence of avian mycoplasma species in India. I. Biological properties of avian mycoplasma species. PMID- 4155871 TI - [Light and electron microscopy of Mycoplasma pneumoniae cells (author's transl)]. PMID- 4155872 TI - [Comments on Sporothrix schenckii var. luriei. Contribution to the diagnostic value of the assimilation of creatinine, creatine and guanidoacetic acid by Sporothrix schenckii (author's transl)]. PMID- 4155873 TI - [A modified simple method for the detection of the different lipolytic activity of microorganisms (author's transl)]. PMID- 4155874 TI - [Isolation of tick-borne encephalitis (TBE) virus from Ixodes ricinus collected in the Kantom Zurich, Switzerland (author's transl)]. PMID- 4155875 TI - [Isolation and identification of a new Salmonella species from sewage S. bazenheid equals 8,20:z 10:1,2 (author's transl)]. PMID- 4155876 TI - Occurrence of a seven-drug-resistance plasmid in two strains of Salmonella typhi murium from diarrheatic patients. PMID- 4155877 TI - [The production of neutralizing antibodies in man after vaccination with Hempt rabies-vaccine (author's transl)]. PMID- 4155878 TI - [Removal of nonspecific inhibitors in the Rubella virus hemagglutination inhibition test employing acetone as compared to kaolin and heparin-MnCl2 pretreatment (author's transl)]. PMID- 4155879 TI - [Blood-pictures in different courses of swine fever infection concerning lymphocytic reactions, cellnecrobiosis, moving forms of lymphocytes ("lysocytes") and reactions of the bone-marrow (author's transl)]. PMID- 4155880 TI - The property changes of two Tahyna virus strains by influence of serial passages in various environments. PMID- 4155881 TI - Plaque S- variant of Semliki Forest virus in poikilothermic cell culture at 20 degrees C. PMID- 4155882 TI - Purification of CV virus by CsCl density gradient centrifugation and extraction of viral DNA by MAK column chromatography. PMID- 4155883 TI - [Fermentation of lactose by permeaseless E. coli in the presence of dimethylsulfoxide (author's transl)]. PMID- 4155884 TI - [Aerogeny and extent of motility in motile E. coli strains (author's transl)]. PMID- 4155885 TI - Studies on phage tail bacteriocins of Proteus rettgeri. PMID- 4155886 TI - Continued epidemiological surveillance of Serratia marcescens infections by bacteriocin typing, with particular reference to strains isolated at Erlangen. PMID- 4155887 TI - Studies on group A (phage tail) bacteriocins of Serratia marcescens. II. Further characterization of subgroup I and II bacteriocins. PMID- 4155888 TI - [The virulence of Pasteurella multocida strains and their neuraminidase production (author's transl)]. PMID- 4155889 TI - [Susceptibility of non-sporing anaerobes of the genera Bacteroides, Fusobacterium, Sphaerophorus, Peptococcus, and Peptostreptococcus to clindamycin (author's transl)]. PMID- 4155890 TI - [Enterotoxin detection in thermostable Clostridium perfringens type A strains isolated from a food poisoning outbreak (author's transl)]. PMID- 4155891 TI - Transferable tetracycline resistance in Salmonella cholerae-suis var. Kunzendorf. PMID- 4155892 TI - [The Ausab test - a radioimmunoassay in the solid phase for the detection of antibodies against HBsAg (author's transl)]. PMID- 4155893 TI - A study of staphylococci isolated from the upper respiratory tract of different animal species. VI. Physiological properties of Staphylococcus aureus strains from horses. PMID- 4155894 TI - [Group F streptococci in guinea pigs (author's transl)]. PMID- 4155895 TI - [Incidence of salmonellosis in Budapest in the years 1956-1971 (author's transl)]. PMID- 4155896 TI - [Incidence of Salmonella serotypes in Budapest in the years 1956-1971 (author's transl)]. PMID- 4155897 TI - R factors and colicins in Escherichia coli strains causing infections of the urinary apparatus. PMID- 4155898 TI - [Employment of the immunological india-ink-reaction according to Geck for the quick demonstration of E. coli enteritis (author's transl)]. PMID- 4155899 TI - [Bacteriological investigations on reptiles and amphibians (author's transl)]. PMID- 4155900 TI - Studies on group A (phage tail) bacteriocins of Serratia marcescens. III. Inhibition of beta-galactosidase activity (ONPG-hydrolysis) in sensitive indicator cells. PMID- 4155901 TI - Studies on group A (phage tail) bacteriocins of Serratia marcescens. IV. Preliminary characterization of receptors of subgroup II bacteriocins. PMID- 4155903 TI - Global ecological surveillance. PMID- 4155902 TI - [Experimental body cavities in rabbits for the analysis of possible bacterial virulence factors (author's transl)]. PMID- 4155904 TI - [Serology of aspergillosis]. PMID- 4155905 TI - [Standardized technic for rubella hemagglutination- and hemagglutination inhibition tests]. PMID- 4155907 TI - [Dicarboxylic amino acids, GABA and serotonin in the hypothalamic area of rats of different ages]. PMID- 4155906 TI - [The effect of denervation and reinervation on rabbit skeletal muscle lactate dehydrogenase and malate dehydrogenases]. PMID- 4155908 TI - [Use of psychological tests in clinical practice]. PMID- 4155909 TI - Obstructive arteritis of Takayasu's type complicated by acute myocardial infarction. PMID- 4155910 TI - [On the etiology of aneurysmatic osseous cyst (author's transl)]. PMID- 4155911 TI - Comparison of the effect of gamma-aminobutyric acid and of sodium salt of gamma hydroxybutyric acid during the ontogeny of rats. PMID- 4155912 TI - Proceedings: Modification of epileptogenic focus by simultaneous application of drugs. PMID- 4155913 TI - Comparison of the antihistaminic effects in skin of a tertiary (promethazine) and a quarternary phenothiazine (N-hydroxyethylpromethazine). PMID- 4155914 TI - Desensitizing treatment in allergy to synthetic corticotrophin: study of three cases. PMID- 4155915 TI - Which must be the concept of adrenergic blockade and potentiation nowadays? PMID- 4155916 TI - [Neurologic complications due to anticholera vaccine]. PMID- 4155917 TI - [Case of leukoencephalomyelitis due to anticholera vaccine]. PMID- 4155918 TI - Beta-Blockers in the management of myocardial ischemia. PMID- 4155919 TI - Psychopharmacology for non-psychiatrists: a review. PMID- 4155920 TI - Legal and related barriers to increased utilization of new health practitioners. PMID- 4155921 TI - The determination of some 1,4-benzodiazepines and their metabolites in body fluids. A review. PMID- 4155922 TI - The role of cytochrome P-450 and P-448 in drug and steroid hydroxylations. PMID- 4155924 TI - Kinetic studies on the mechanism of conversion of cholesterol to pregnenolone. PMID- 4155923 TI - Studies on the partially purified heme protein P-450 from the adrenal cortex. PMID- 4155925 TI - Drugs, alcohol and sex hormones: a molecular perspective of the receptivity of cytochrome P-450. PMID- 4155926 TI - Activator and inhibitor factors in cholesterol side-chain cleavage. PMID- 4155927 TI - The in vivo effect of ACTH on utilization of reducing energy for pregnenolone synthesis by adrenal mitochondria. PMID- 4155928 TI - Lifetime of adrenal cytochrome P-450 as influenced by ACTH. PMID- 4155929 TI - Studies on the aromatization of C-19 androgens. PMID- 4155930 TI - Comparative studies on mitochondrial and partially purified bovine corpus luteum cytochrome P-450. PMID- 4155931 TI - Biochemical studies on cytochrome P-450 solubilized from liver microsomes: partial purification and mechanism of catalysis. PMID- 4155932 TI - Eelctron transport system for adrenocortical mitochondrial steroid hydroxylation reactions: the mechanism of the hydroxylation reactions and properties of the flavoprotein-iron-sulfur protein complex. PMID- 4155934 TI - [Chromosome studies of collagen diseases]. PMID- 4155933 TI - Hydralazine and beta-adrenergic blockade in the treatment of hypertension. PMID- 4155935 TI - Cutaneous periarteritis nodosa. PMID- 4155936 TI - Influence of serotonin on water intake and the renin-angiotensin system in the rat. PMID- 4155937 TI - The energy-yielding reactions of Peptococcus prevotii, their behaviour on starvation and the role and regulation of threonine dehydratase. PMID- 4155938 TI - Pharmacological studies on some anaphylactic reactions in mice. PMID- 4155939 TI - [Metabolic characteristics of the skeletal muscles in the Duchenne form of progressive muscular dystrophy]. PMID- 4155940 TI - [Ovarian interstitial tissue in disordered sex hormone balance]. PMID- 4155941 TI - [Histoenzymatic characteristics of primary lung cancer]. PMID- 4155942 TI - [Histochemical study of certain connective tissue tumors]. PMID- 4155943 TI - [Histoenzymological characteristics of carbohydrate metabolism in invasive breast cancer]. PMID- 4155944 TI - Diagnosis, treatment planning and referral by school dental therapists. PMID- 4155945 TI - A dental survey of an antenatal population. PMID- 4155946 TI - Community dental health survey. Sydney Metropolitan Area-1972. PMID- 4155947 TI - General medical care in China. PMID- 4155948 TI - Differential effects of 2-oxo acids on pyruvate utilization and fatty acid synthesis in rat brain. AB - 1. The effects of 2-oxo-4-methylpentanoate, 2-oxo-3-methylbutanoate and 2-oxo-3 methylpentanoate on the activity of pyruvate dehydrogenase (EC 1.2.4.1), citrate synthase (EC 4.1.3.7), acetyl-CoA carboxylase, (EC 6.4.1.2) and fatty acid synthetase derived from the brains of 14-day-old rats were investigated. 2. The pyruvate dehydrogenase enzyme activity was competitively inhibited by 2-oxo-3 methylbutanoate with respect to pyruvate with a K(i) of 2.04mm but was unaffected by 2-oxo-4-methylpentanoate or 2-oxo-3-methylpentanoate. 3. The citrate synthase activity was inhibited competitively (with respect to acetyl-CoA) by 2-oxo-4 methylpentanoate (K(i)~7.2mm) and 2-oxo-3-methylbutanoate (K(i)~14.9mm) but not by 2-oxo-3-methylpentanoate. 4. The acetyl-CoA carboxylase activity was not inhibited significantly by any of the 2-oxo acids investigated. 5. The fatty acid synthetase activity was competitively inhibited (with respect to acetyl-CoA) by 2 oxo-4-methylpentanoate (K(i)~930mum) and 2-oxo-3-methylpentanoate (K(i)~3.45mm) but not by 2-oxo-3-methylbutanoate. 6. Preliminary experiments indicate that 2 oxo-4-methylpentanoate and 2-oxo-3-phenylpropionate (phenylpyruvate) significantly inhibit the ability of intact brain mitochondria from 14-day-old rats to oxidize pyruvate. 7. The results are discussed with reference to phenylketonuria and maple-syrup-urine disease. A biochemical mechanism is proposed to explain the characteristics of these diseases. PMID- 4155949 TI - 7 Alpha-hydroxylation of cholesterol by reconstituted systems from rat liver microsomes. PMID- 4155950 TI - [Statistical evaluation of a cooperative study toward investigation of the effectiveness of the coronary stimulant dilazep in ischemic heart disease. 3. Influence of the duration of therapy and co-medication on the therapeutic result. Secondary effects and discontinuation of therapy]. PMID- 4155951 TI - [Statistical evaluation of a cooperative study toward investigation of the effectiveness of the coronary stimulant dilazep in ischemic heart disease. 4. Results of a summarizing evaluation with factor analysis and multiple regression analysis]. PMID- 4155952 TI - [Experimental studies on the influence of thiamazol on clinicochemical parameters of cholestasis]. PMID- 4155953 TI - Effect of tolamolol versus propranolol on cardiovascular haemodynamics in patients with angina. PMID- 4155954 TI - Steriod metabolism by human normal thyroid, nodular goitre and thyroid cancer. PMID- 4155955 TI - The effect of cultural conditions on the susceptibility of staphylococci to killing by the cationic proteins from rabbit polymorphonuclear leucocytes. PMID- 4155956 TI - The reduction of 3-phosphoglycerate by reconstituted chloroplasts and by chloroplast extracts. PMID- 4155958 TI - [Purine metabolism in Drosophila melanogaster cells in culture in vitro: purine interconversion]. PMID- 4155957 TI - The shikimate pathway : II. Stereospecificity of hydrogen transfer catalyzed by NADPH-dehydroshikimate reductase of E. coli. PMID- 4155959 TI - Factors affecting muscle activation in the hydroid Tubularia. PMID- 4155960 TI - A familial syndrome of short stature associated with facial dysplasia and genital anomalies. AB - The following report presents the clinical findings and natural history of a growth disorder affecting seven male patients from the same family. In addition to short stature they all had a similar pattern of anomalies and the condition appears to constitute a previously undescribed, probably X-linked recessive, nosologic entity. PMID- 4155961 TI - Multiple endocrine adenomatosis presenting as Zollinger-Ellison syndrome, nonbeta islet cell adenoma, parathyroid adenoma, renal calculi, bronchial carcinoid, insulinoma, hepatic hamartoma, etc. PMID- 4155962 TI - Genetic disorders involving parathyroid hormone and calcitonin. AB - There are several genetic disorders that cause abnormalities in the hormonal regulation of calcium metabolism. These include familial hyperparathyroidism, multiple endocrine adenomatosis, pseudohypoparathyroidism and kindreds with multiple cases of medullary carcinoma of the throid. The clinical characteristics of these several syndromes are outlined. Several tests of endocrine function, either determination of hormone secretory rates or biochemical manifestations of the action of hormones, are helpful in delineating genetic modes of transmissions of these disorders. radioimmunoassays are becoming important adjuncts in the diagnosis of hyperparathyroidism and medullary carcinoma of the thyroid. Determination of 3',5'-adenosine monophosphate in urine in response to parathyroid hormone allows accurate diagnosis of pseudohypoparathyroidism. PMID- 4155963 TI - Familial tumor endocrinopathies. AB - The spectrum of familial tumor endocrinopathies is broad; what has been described here probably represents only a small part of the entire subject. No consideration has been given to treatment, as this is covered in standard tests. It is important to recognize that, potentially, any endocrine tumor may be familial, and both a detailed family study and longitudinal follow-up are necessary if the mode of inheritance and the degree of clinical variability are to be established with certainty. PMID- 4155964 TI - Relationship of hyperparathyroidism to multiple endocrine adenomatosis. AB - An experience with 8 families with 56 members affected with hyperparathyroidism has emphasized that heredity is an important etiologic factor in this disease. The finding of other endocrine involvement in several members of these families has suggested that hereditary hyperparathyroidism is only a part of the autosomal dominantly inherited multiple endocrine adenomatosis syndrome. This association with hyperparathyroidism, a disease being found with increasing frequency as an inherited condition, provides evidence that multiple endocrine adenomatosis is more common than previously suspected. PMID- 4155965 TI - Dermatologic disorders in institutionalized mental defectives. AB - Skin diseases among the retarded fall into four categories--common dermatoses, behavioral disorders, iatrogenic manifestations produced by drug therapy and a group of congenital, hereditary and unexplained cases. The last three classifications are briefly reviewed in the following article. PMID- 4155966 TI - An unidentified syndrome with abnormality of skin and hair. PMID- 4155967 TI - [Method for studying deviations from the normal duration of the cardiac cycle]. PMID- 4155968 TI - [Effect of o,p'-dichlorodiphenyldichloroethane on glutathione reductase activity and on the SH-group content in the adrenals of dogs]. PMID- 4155969 TI - Blockade of peripheral vascular responses to isoprenaline by three beta adrenoceptor antagonists in the anaesthetized dog. AB - 1 A dog's hind limb was vascularly isolated by strong nylon snares and its sympathetic nerve supply interrupted. Blood was perfused at constant flow into the femoral artery and drained from the femoral vein. In some dogs the cardiac nerves were cut.2 Isoprenaline infused intravenously caused an increase in heart rate and a decrease in arterial resistance.3 Practolol (2 mg/kg) effectively blocked heart rate responses to isoprenaline infused at up to 10 mug/min but was relatively ineffective in blocking arterial responses. ICI 66082 (2 mg/kg) reduced vasomotor responses and propranolol (0.5 mg/kg) abolished vasomotor responses.4 Small cumulative doses of beta-adrenoceptor antagonists were given to some dogs. Practolol blocked heart rate responses in lower doses than were required to block vasomotor responses. Propranolol preferentially blocked vasomotor responses and ICI 66082 was intermediate between the other two in its effects. PMID- 4155970 TI - The actions of a new beta-adrenoceptor blocking drug, ICI 66082, on the rabbit papillary muscle and on the dog heart. AB - 1 The actions of 4-(2-hydroxy-3-isopropylaminopropoxy) phenyl acetamide (ICI 66082), a new beta-adrenoceptor blocking drug, on the twitch response of the isolated papillary muscle of the rabbit and on dP/dt max and free heart rate of a denervated dog heart preparation, are described.2 ICI 66082 (up to 1 mg/ml) did not produce any depression of the twitch response of the rabbit papillary muscle. ICI 66082 antagonized the action of isoprenaline on this preparation at a concentration of 0.01 mug/ml.3 ICI 66082 (0.5-1.0 mg/kg intravenously) reduced the control value of dP/dt max in four dog preparations by a mean value of 529 mmHg/s (s.e. mean +/- 139 mm Hg/s), with no significant change in free heart rate. Antagonism of the effect of isoprenaline on dP/dt max and on free heart rate was demonstrated with ICI 66082 (0.1 mg/kg).4 ICI 66082 (1.0-1.5 mg/kg) produced no significant changes in dP/dt max or in free heart rate in four dogs pretreated with reserpine. A significant reduction (16% of the control value) in dP/dt max was observed with ICI 66082 at a high dose of 40-50 mg/kg.5 It is concluded that ICI 66082 is a competitive antagonist against the actions of isoprenaline on cardiac muscle, has no negative inotropic action (unless the dose exceeds 40 mg/kg) and lacks intrinsic sympathomimetic activity. PMID- 4155971 TI - Effects of tiprenolol, practolol and propranolol on experimental ventricular tachyarrhythmias. AB - 1 Low doses of tiprenolol (0.01-0.02 mg/kg) and propranolol (0.05 mg/kg) abolished the ventricular arrhythmias produced by the intravenous injection of adrenaline in anaesthetized dogs respired with halothane.2 Larger doses of tiprenolol (2.0-4.0 mg/kg) restored sinus rhythm in four of five dogs with ventricular tachycardia produced by toxic doses of ouabain. Propranolol (2.0-4.0 mg/kg) had the same effect in each of four dogs.3 Both tiprenolol (4.0-8.0 mg/kg) and propranolol (4.0 mg/kg) increased the frequency of sinus beats and reduced the ventricular rate in dogs with ventricular tachycardia 20-44 h after ligation of a coronary artery.4 Practolol (0.5-16.0 mg/kg) did not reduce the ventricular rate or increase the frequency of sinus beats in dogs with ventricular tachycardia after ligation of a coronary artery.5 In dogs with ouabain-induced ventricular tachycardia mean arterial pressure was reduced after the administration of tiprenolol (0.5-8.0 mg/kg) or propranolol (4.0-8.0 mg/kg). Depression of sinus and atrioventricular nodal function, and of intraventricular conduction developed in some of the dogs given tiprenolol (4-8 mg/kg) or propranolol (8.0 mg/kg).6 The administration of tiprenolol (1.0-8.0 mg/kg) or propranolol (4.0-8.0 mg/kg) depressed the arterial pressure and caused the deaths of some dogs in which a coronary artery had been ligated. Such deaths did not occur in the group which had been given toxic doses of ouabain. PMID- 4155973 TI - Investigations on the mode of action of ergotamine in the isolated femoral vein of the dog. AB - 1 Experiments on spiral strips cut from the femoral vein of dogs suspended in Krebs-Henseleit solution were carried out.2 Ergotamine caused stimulation in concentrations about 350 times lower than noradrenaline (ED(50) of ergotamine = 2.2 x 10(-9) M; ED(50) of noradrenaline = 7.6 x 10(-7) M), but the maximal responses to ergotamine were only about one third those to noradrenaline.3 The pA(2) value of ergotamine against noradrenaline was 8.8.4 The effects of ergotamine can be blocked by prior administration of phentolamine. The pA(2) value for phentolamine against ergotamine was 6.8 and the pA(2) value for phentolamine against noradrenaline was 7.5.5 It is concluded that the stimulant action of ergotamine on smooth vascular muscle probably is mediated mainly via alpha-adrenoceptors. PMID- 4155972 TI - Influence of SKF-525A congeners, strophanthidin and tissue-culture media on desensitization in frog skeletal muscle. AB - 1 Microelectrodes have been used to follow changes in membrane potential at end plate regions of frog skeletal muscle fibres exposed to carbachol; the depolarizing drug was applied to narrow strips of muscle in a rapidly flowing solution containing relatively impermeant anions rather than chloride.2 During prolonged applications of carbachol (10 to 20 muM), the depolarization caused by the drug showed a gradual decline which was attributed to desensitization.3 Desensitization was little if at all affected by supplementing the external solution with factors present in tissue-culture media, or by treating the muscle with strophanthidin (25 muM).4 The rate of repolarization in the presence of carbachol (10 to 20 muM) was greatly increased by the SKF-525A congeners pipenzolate bromide (10 muM) and adiphenine hydrochloride (1 muM). The desensitization-enhancing action of these compounds is discussed. PMID- 4155974 TI - The action of indoramin and other compounds on the uptake of neurotransmitters into rat cortical slices. AB - Indoramin has been tested for its ability to inhibit the uptake of tritiated (-) noradrenaline and 5-hydroxytryptamine into rat brain cortical slices. Other alpha blocking agents and tricycic antidepressants were included for comparison. Activity against noradrenaline uptake is probably not important in the therapeutic action of indoramin. However, inhibition of 5-hydroxytryptamine uptake may be responsible for the sedation in high dosage noted by some investigators, PMID- 4155975 TI - The long-term regulation of tyrosine hydroxylase activity in cultured sympathetic ganglia: role of ganglionic noradrenaline content. AB - 1 An organ culture system is described for the in vitro maintenance of superior cervical sympathetic ganglia taken from mice of any age. The relation of tyrosine hydroxylase (T-OH) activity to ganglionic noradrenaline (NA) content has been investigated under various culture conditions.2 Depolarizing stimuli such as raised extracellular potassium and ouabain evoked increases of approximately 70% in the T-OH activity of cultured ganglia over a 48 h period. Exposure to a high concentration of potassium (high K(+)) for 30 min at the start of a 48 h culture was sufficient to elicit significant increases in T-OH activity.3 Depolarization induced rises in T-OH activity were observed after culture in the presence or absence of nerve growth factor.4 The NA content of ganglia, cultured for 48 h in the presence of high K(+), ouabain, reserpine, clorgyline and alpha-methyl-p tyrosine, showed no constant relation to their T-OH activity.5 Dibutyryl cyclic adenosine 3'-5'-monophosphate (dibutyryl cyclic AMP) mimicked high K(+) in its effect on ganglionic T-OH activity and NA content. Theophylline enhanced the potassium effects.6 Rises in the T-OH activity of ganglia cultured in the presence of high K(+) and dibutyryl cyclic AMP were abolished if the protein synthesis inhibitors cycloheximide or actinomycin D were present in the culture medium.7 It is concluded that the link between prolonged depolarization and rises in T-OH activity does not seem to depend upon changes in ganglionic NA content. In the intact animals, trans-synaptic modulation may take the form of a depolarization-induced rise in the cyclic AMP content of sympathetic ganglionic neurones leading to nuclear mediated synthesis of T-OH. PMID- 4155976 TI - Effect of preganglionic nerve stimulation on sensitivity of the superior cervical ganglion to nicotinic blocking agents. AB - 1 Periodic stimulation (every 10 min) of the cervical sympathetic nerve increased the ganglionic block by low concentrations of chlorisondamine (CHL) in the superior cervical ganglion of the cat when compared to the contralateral unstimulated side.2 Periodic stimulation of the postganglionic nerve was ineffective in increasing the block.3 Ganglionic block by low concentrations of mecamylamine had the same stimulus dependency, but ganglionic block by any dose of hexamethonium was not influenced by nerve stimulation.4 Physostigmine infused together with CHL increased the rate of onset of block produced by CHL. Atropine had no apparent effect on the development of ganglionic block by CHL.5 Repeated intra-arterial injections of 1,1-dimethyl-4-phenylpiperazinium into the circulation of the superior cervical ganglion increased the magnitude of block produced by CHL. Similar injections of methacholine had no effect on ganglionic block produced by CHL.6 The results are interpreted to indicate that activation of ganglionic nicotinic receptors increased the affinity of receptors for CHL and mecamylamine. PMID- 4155977 TI - Actions of putative transmitters in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations. AB - 1 Histamine (0.02-0.1 mug/ml) contracted the chicken rectum preparation. This effect was antagonized by mepyramine (0.01 mug/ml) but not by hyoscine (0.02 mug/ml).2 5-Hydroxytryptamine (0.05-0.25 mug/ml) relaxed the rectum preparation and at higher concentration produced a biphasic response. These responses were not antagonized by methysergide (0.01 mug/ml), and the relaxation was not antagonized by tetrodotoxin (0.1 mug/ml) or a combination of propranolol (0.05 mug/ml) and phentolamine (0.1 mug/ml).3 Neither mepyramine (0.1 mug/ml) nor methysergide (0.01 mug/ml) antagonized the contractions produced by nerve stimulation in vagus nerve/oesophagus and Remak nerve/rectum preparations.4 5 Hydroxytryptamine (2 mug/ml) in the presence of methysergide (0.01 mug/ml), inhibited the contractions produced by nerve stimulation in Remak nerve/rectum and vagus nerve/oesophagus preparations.5 Adenosine, adenosine 5'-phosphate (AMP), adenosine 5'-diphosphate (ADP) and adenosine 5'-triphosphate (ATP), in order of decreasing potency, produced slow contractions in most oesophagus preparations. The action of ATP in this preparation was antagonized by tetrodotoxin (0.1 mug/ml), hyoscine (0.1 mug/ml) and strychnine (5 mug/ml).6 Desensitization of the vagus nerve/oesophagus preparation to ATP did not produce any antagonism of the contractions to nerve stimulation.7 Adenosine and AMP produced relaxations and ADP and ATP contractions in the rectum preparation. ATP was about 100 times as potent as ADP in producing fast contractions which were not antagonized by tetrodotoxin, hyoscine or strychnine.8 Desensitization of the Remak nerve/rectum preparation to ATP resulted in the contractions to nerve stimulation and acetylcholine being inhibited to the same extent.9 Prostaglandin E(2) produced slow contractions in the oesophagus and rectum preparations which were not antagonized by tetrodotoxin (0.1 mug/ml). Polyphloretin phosphate (10 mug/ml) antagonized spontaneous movements and responses to prostaglandin E(2) in the rectum but not the oesophagus.10 Neither polyphloretin phosphate (60 mug/ml) nor indomethacin (20-100 mug/ml) antagonized the contractions produced by nerve stimulation in vagus nerve/oesophagus (with hyoscine in the bathing solution) and Remak nerve/rectum preparations.11 These experiments seem to exclude histamine, 5 hydroxytryptamine, adenosine and its nucleotides and prostaglandin E(2) as possible motor transmitters in synapses and neuromuscular junctions in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations. PMID- 4155978 TI - The specificity of some agonists and antagonists for nicotine-sensitive receptors in ganglia. AB - 1 The guinea-pig isolated ileum has been used to estimate the ability of substituted phenylalkylonium salts (related to nicotine) to stimulate or block receptors in ganglia. The effects of hexamethonium were used to indicate which were the most specific ganglion stimulants; these were tested on the blood pressure of pithed rats and for neuromuscular blocking activity on the rat diaphragm preparation.2m-Hydroxyphenylpropyltrimethylammonium and 3,4 dihydroxyphenethyltrimethylammonium (coryneine, ;quaternary dopamine') were the most active and specific ganglion stimulants but their usefulness in vivo may be limited by their neuromuscular blocking activity. The analogous tertiary compounds are being investigated.3 The affinities of substances which were blocking agents at ganglionic receptors were measured on the isolated ileum with m-hydroxyphenylpropyltrimethylammonium as agonist. The affinities of selected compounds for postganglionic receptors were measured in experiments on the ileum in the presence of hexamethonium and with carbachol as agonist. Some of the compounds were tested for neuromuscular blocking activity on the rat diaphragm.4 Phenylbutyldiethylamine had ganglion-blocking activity greater than pempidine and little postganglionic blocking or neuromuscular blocking activity. Its triethylammonium analogue had higher ganglion-blocking activity but had appreciable neuromuscular blocking activity.5 The aromatic ring system is not essential either for activity or affinity and the effects of substituents are not related to their effects on electron distribution. Stimulant activity is enhanced only by hydroxyl or amino groups in suitable positions; it is not improved by the presence of rigid features (double or triple bonds or a cyclopropane ring) in the side chain. Affinity is slightly increased by chloro or bromo groups in suitable positions but the unsubstituted compounds are among those with the highest affinity. Substituents have similar effects on affinity for postganglionic receptors, though for these receptors the compounds mostly have only about one tenth of their affinity for ganglionic receptors. PMID- 4155979 TI - Antagonism of inhibitory amino acid action by tubocurarine. AB - A comparison has been made of the antagonism by microelectrophoretically administered (+)-tubocurarine, bicuculline methochloride and strychnine of the inhibition of spinal interneurones and Renshaw cells in the cat by glycine and gamma-aminobutyric acid. The results indicate that (+)-tubocurarine would be of little use in assessing which of these amino acids was the transmitter at central inhibitory synapses. PMID- 4155980 TI - Proceedings: Convulsant substances as antagonists of GABA and presynaptic inhibition in the cuneate nucleus. PMID- 4155981 TI - Proceedings: The action of cinnarizine and of phentolamine on the noradrenaline dependent calcium influx in vascular smooth muscle. PMID- 4155982 TI - Proceedings: Vascular histamine receptors in the cat. PMID- 4155983 TI - Proceedings: Pharmacological studies with LL 21-945, a new beta-adrenoceptor blocking agent with a long duration of action. PMID- 4155984 TI - Proceedings: The hypoglycaemic action of ICI 66082 (4-(2-hydroxy-3-isopropyl aminopropoxy) phenyl acetamide) in the rat. PMID- 4155985 TI - Bicuculline and the frog spinal cord. AB - 1 The effects of bicuculline on dorsal and ventral root activity and upon the depressant effect of gamma-aminobutyric acid (GABA) and glycine on ventral root responses have been studied on the isolated spinal cord of the frog.2 In the absence of stimulation, the alkaloid induced a variety of activity of which the most notable was phasic simultaneous slow wave depolarization in the dorsal and ventral roots which could be reduced or suppressed by magnesium.3 With low concentrations of bicuculline, the adjacent dorsal root response evoked by a single stimulus was depressed maximally before an increase in the ventral root response could be discerned.4 The bicuculline-induced dorsal root activity (in the absence of stimulation) was still apparent at times when the evoked dorsal root response was reduced.5 Bicuculline did not differentiate between the depressant effects of GABA and glycine on the evoked ventral root responses.6 The excitant effects of bicuculline reported here did not appear to be attributable to specific antagonism of the postsynaptic depressant action of GABA. PMID- 4155986 TI - Implication of gastric mucosal histamine in inhibition by isoprenaline of pentagastrin-induced gastric secretion. AB - 1 The effect of isoprenaline on pentagastrin-induced gastric secretion was studied in conscious rats with Heidenhain pouches. The influence of isoprenaline on pentagastrin-induced release and formation of gastric mucosal histamine was also examined.2 Isoprenaline strongly inhibited pentagastrin-induced acid secretion, an inhibition which could not be overcome by increasing the dose of pentagastrin.3 Propranolol blocked the inhibitory effect of isoprenaline on pentagastrin-induced acid secretion.4 Isoprenaline enhanced pepsin secretion induced by pentagastrin, an effect which was blocked by propranolol.5 Isoprenaline reduced the increase in formation and release of gastric mucosal histamine following pentagastrin infusion, an inhibitory influence which was almost completely blocked by propranolol.6 The inhibition by isoprenaline of pentagastrin-induced acid secretion is tentatively related to alterations in gastric mucosal histamine occurring simultaneously. PMID- 4155987 TI - A non-adrenergic inhibitory nervous pathway in guinea-pig trachea. AB - 1 Electrical stimulation of the guinea-pig isolated tracheal tube causes a biphasic response, initially excitatory and then inhibitory. The excitatory response was abolished by atropine leaving the inhibitory response unaffected.2 The inhibitory response was greatly reduced but not abolished by propranolol or guanethidine. A residual inhibitory response was still present in tracheas in which sympathetic nerve function had been abolished by pretreatment with syrosingopine or 6-hydroxydopamine. These results show that the inhibitory response is predominantly adrenergic but that a small non-adrenergic component is also present.3 The non-adrenergic inhibitory response was abolished by lignocaine and tetrodotoxin suggesting that it is nervous in origin.4 Optimal stimulation parameters for the predominantly adrenergic inhibitory response were a pulse width of 0.7-2 ms, a stimulation period of 7 s and a frequency of 20 Hz. For the non-adrenergic inhibitory response, optimal stimulation parameters were a pulse width of 2 ms, a stimulation period of 12 s and a frequency of 20 Hz.5 Evidence obtained with pharmacological antagonists, enzyme inhibitors and activators suggested that the transmitter mediating the non-adrenergic inhibitory nervous response is unlikely to be: acetylcholine, histamine, 5-hydroxytryptamine, cyclic 3',5'-adenosine monophosphate or a prostaglandin.6 The adenosine uptake blocking drugs dipyridamole, hexobendine and Dilazep potentiated the non-adrenergic inhibitory nervous response and unmasked inhibitory responses to adenosine and adenosine 5'-triphosphate.7 It is concluded that electrical stimulation of the guinea-pig trachea, in addition to activating cholinergic and adrenergic nervous pathways, may activate a separate and distinct inhibitory nervous pathway. This pathway has some features in common with the non-adrenergic non-cholinergic inhibitory pathways in gastro-intestinal muscle. PMID- 4155988 TI - The rabbit rectococcygeus: a ganglion-free parasympathetically innervated preparation. AB - 1 Isolated, desheathed preparations of the rabbit rectococcygeus muscle were relatively insensitive to spasmogens other than muscarinic drugs. Transmural stimulation with 1-50 pulses (0.2-0.4 ms at 10 Hz) elicited graded twitches which were abolished by tetrodotoxin and were therefore neurogenic; longer pulses sometimes triggered tetrodotoxin-resistant myogenic contractions.2 Twitches elicited by 0.2-0.4 ms pulses were due to post-ganglionic excitation because they were not reduced by hexamethonium, pentolinium or dimethyltubocurarine, or by ganglion-paralyzing concentrations of nicotine.3 The acetyl- and butyryl cholinesterase activities of the rectococcygeus were determined manometrically and could be selectively inhibited by BW 284C51 (1:5-bis-(4-allyl dimethylammonium-phenyl)-pentan-3-one dibromide) and iso-OMPA (tetramonoisopropylpyrophosphortetramide), respectively. Single-pulse twitches were greatly potentiated in amplitude and duration only when both cholinesterases were inhibited.4 The preparations could not be made to contract by nicotine (2.1 21 muM) even after cholinesterase inhibition, suggesting an absence of ganglion cells; with nicotine (105-210 muM) small, atropine-susceptible responses were elicited, which were non-ganglionic because they were not reduced by tetrodotoxin.5 Rectococcygeus preparations that had been treated with physostigmine released acetylcholine into the bath fluid on electrical stimulation.6 The motor transmission was paralyzed by botulinum toxin (Type A) and abolished by atropine; the block of muscarinic receptors by atropine was effective against both endogenous and exogenous acetylcholine.7 Inhibitory adrenoceptors and scanty motor alpha-adrenoceptors were detected in the smooth muscle.8 Strong inhibitions of motor transmission and of rhythmic activity were produced by noradrenaline (but not by tyramine), by isoprenaline, and, after phentolamine, also by adrenaline and phenylephrine. These inhibitions were only slightly reduced by propranolol and rather more by pindolol.9 Experiments on preparations retaining their extrinsic nerve supply suggest an absence of ganglionic relays in the last 1-2 cm of the motor nerve pathway to this muscle.10 Some contrasting properties of the adjacent caudo-anal muscle, including the poor motor responses to transmural stimulation, are described. PMID- 4155989 TI - Prostaglandin inactivation in guinea-pig lung and its inhibition. AB - 1 Several compounds were tested for their ability to inhibit prostaglandin metabolism in guinea-pig lungs.2 In isolated perfused lungs polyphoretin phosphate (PPP) inhibited prostaglandin metabolism being active at concentrations greater than 100 ng/ml and having an ID(50) of 2.15 mug/ml against prostaglandin E(2) metabolism and 1.55 mug/ml against prostaglandin F(2alpha) metabolism.3 At these doses no antagonism of the actions of prostaglandins was seen.4 Diphloretin phosphate (DPP) was more active on a weight for weight basis and inhibition of inactivation of prostaglandins was seen at concentrations greater than 10 ng/ml, the ID(50) being 0.54 mug/ml against both prostaglandins E(2) and F(2alpha).5 At concentrations greater than 5 mug/ml DPP antagonized the actions of prostaglandin F(2alpha).6 The sulphydryl-binders N-ethyl maleimide (NEM) and sodium p chloromercuriphenyl sulphonate (PCMS) also inhibited prostaglandin inactivation by guinea-pig isolated lungs.7 All four compounds inhibited prostaglandin metabolism by a crude enzyme preparation from guinea-pig lungs. PMID- 4155991 TI - The effects of three beta-adrenoceptor blocking drugs on isolated preparations of skeletal and cardiac muscle. AB - 1 The effects of propranolol, oxprenolol and practolol on the isometric twitch responses to electrical stimulation of isolated diaphragm muscles from the rat and of isolated papillary muscles from the rabbit are described.2 Depression of the twitch responses of the diaphragm muscle was produced by propranolol (20 mug/ml), by oxprenolol (100 mug/ml) and by practolol (500 mug/ml).3 Depression of the twitch responses of the papillary muscles was produced by propranolol (20 mug/ml) by oxprenolol (100 mug/ml) and by practolol (200 mug/ml).4 No increase of twitch tension was produced by oxprenolol or practolol on either tissue.5 It is concluded that propranolol, oxprenolol and practolol produce negative inotropic actions on isolated cardiac muscle by a mechanism unrelated to blockade of beta adrenoceptors and which occurs at doses which are well in excess of those doses required to produce beta-blockade. PMID- 4155990 TI - Effect of sympathomimetic amines on the histamine forming capacity of human leucocytes. AB - 1 The effects of alpha- and beta-adrenoceptor stimulants on the histamine-forming capacity (HFC) of human isolated leucocytes have been studied, in vitro.2 It was confirmed that antigen significantly stimulates the HFC of human leucocytes.3 beta-Adrenoceptor stimulants, such as isoprenaline and salbutamol (10(-6)-10( 3)M) significantly inhibited the HFC of human leucocytes in the presence and absence of antigen. At concentrations lower than 10(-6)M, this effect was not observed. In general the degree of inhibition of HFC by beta-adrenoceptor stimulants followed their potency as beta-adrenoceptor stimulants.4 alpha Adrenoceptor stimulants significantly stimulated leucocyte HFC; noradrenaline within a limited concentration of 10(-6)M, while stimulation was seen consistently with phenylephrine at concentrations of 10(-7)-10(-4)M. Adrenaline, which stimulates both alpha- and beta-adrenoceptors, produced small inhibition, no effect, or a degree of stimulation.5 Phentolamine, an alpha-adrenoceptor blocking agent, produced an effect opposite to that of the alpha-adrenoceptor stimulants, i.e. a significant inhibition of the HFC of human isolated leucocytes. PMID- 4155992 TI - Beta-adrenoceptor blocking agents and responses to adrenaline and 5 hydroxytryptamine in rat isolated stomach and uterus. AB - 1 Four beta-adrenoceptor blocking agents, (+/-)- and (+)-propranolol, practolol and oxprenolol, were found to antagonize, apparently competitively, the responses of both the rat isolated stomach and uterus to 5-hydroxytryptamine (5-HT).2 The pA(2) values for each of these agents as antagonists of the contractile action of 5-HT on the rat stomach were found to be: (+/-)-propranolol, 6.08; (+) propranolol, 4.94; practolol, 3.43; and oxprenolol, 5.99. These values were very similar to the corresponding figures for antagonism of 5-HT-induced contractions of the uterus.3 pA(2) values for antagonism of adrenaline-induced relaxations by the four blocking agents on the rat stomach and uterus did not differ from the values for 5-HT blockade.4 To antagonize contractile responses to acetylcholine of the rat stomach it was necessary to give 100 times more (+/-)-propranolol than was needed to antagonize responses to 5-HT. PMID- 4155993 TI - Evidence for involvement of 5-hydroxytryptamine in the actions of amphetamine. AB - 1 Pargyline treatment, 1 h before (+)-amphetamine (1 mg/kg), reduced amphetamine stimulated motor activity. This inhibition was reversed in animals pretreated with p-chlorophenylalanine (PCPA).2 Following treatment with PCPA or 5,6 dihydroxytryptamine (5,6-DHT), amphetamine-induced locomotor activity was significantly potentiated. The increased response to amphetamine in PCPA-treated rats was reversed in animals pretreated with 5-hydroxytryptophan.3 The inhibition of amphetamine-stimulated locomotor activity by treatment with 6-hydroxydopamine was not reversed by PCPA treatment.4 Stereotypies produced by amphetamine were not found to be altered by depletion of 5-hydroxytryptamine.5 Induction of adrenal tyrosine hydroxylase activity produced by chronic amphetamine administration was significantly potentiated by PCPA, emphasizing the involvement of a 5-hydroxytryptamine inhibitory system in more than one action of amphetamine. PMID- 4155995 TI - [Possibilities in following the changes in speech manifestations during a course of the pedagogic process]. PMID- 4155994 TI - Comparison of the effects of propranolol and ICI 66082 in blocking the renin releasing effect of renal nerve stimulation in the cat. AB - The comparative effectiveness of propranolol and ICI 66082, in inhibiting the release of renin from the kidney resulting from renal nerve stimulation, has been studied in the cat. Over the dose range 0.17-0.68 x 10(-5) mol/kg propranolol there was a dose-response relationship with the increase of plasma renin activity (PRA) achieved after 10 min stimulation. Over the dose range 0.75-1.69 x 10(-5) mol/kg ICI 66082 also inhibited the release of renin caused by nerve stimulation, but was about five times less effective than propranolol. It would appear from these data that the beta-adrenoceptors within the kidney mediating renin release are distinctly different from those of the heart. PMID- 4155996 TI - [General principles of the use of inhibitors of adrenergic receptors]. PMID- 4155998 TI - Influences of some freshwater plants on the development and survival of mosquito larvae in British Columbia. PMID- 4155997 TI - Oxidative phosphorylation by chondrocyte mitochondria. PMID- 4155999 TI - Soluble factors and the immune response: in vitro studies of the immunosuppression induced by the graft-versus-host reaction. PMID- 4156000 TI - Inhibition of erythroid cell growth by allogeneic murine lymphocytes. Evidence for a synergism between lymph node cells and thymocytes. PMID- 4156001 TI - [Psychopharmacological treatment of psychosomatic disorders in gynecology (author's transl)]. PMID- 4156002 TI - [Conclusions gained from the Federal Conference on Psychosomatic and Sexual Problems in Gynecology and Obstetrics, Bonjnice 1973 (author's transl)]. PMID- 4156003 TI - Disorders of the autonomic nervous system. Chapter 4. Disorders of cardiac control. PMID- 4156004 TI - Use of bromazepam in obsessional, phobic and related states. PMID- 4156005 TI - Decoding of regulatory signals at the microbial surface. PMID- 4156006 TI - [Functional results after duodenopancreatectomy (with special consideration of iron absorption, breath test, and serum gastrin) (author's transl)]. PMID- 4156007 TI - [Dental caries surveys]. PMID- 4156008 TI - Simultaneous determination of sulthiame and diphenylhydantoin serum levels by gas liquid chromatography. PMID- 4156009 TI - Proceedings: An abnormality of secondary energy resources in epileptogenic human brain. PMID- 4156010 TI - [Reflex effects from the afferent fibers of the vagus nerve on the blood flow in the skeletal muscle and coronary vessels and cardiac contactility]. PMID- 4156011 TI - [Proceedings: Mechanism of stimulation of insulin secretion by beta 2 receptor stimulants. 2]. PMID- 4156012 TI - [Proceedings: Endocrinological study of retentio testis]. PMID- 4156013 TI - [Proceedings: Experimental transplantable cancer and cyclic nucleotides. I. Adenyl cyclase activity and protein phosphorylating enzymes in transplantable prostatic cancer]. PMID- 4156014 TI - [Proceedings: Effect of adrenergic agents on the oxytocin content of the rat hypothalamus and pituitary gland]. PMID- 4156015 TI - Coordinate regulation of enzyme inducibility and developmental competence in Aspergillus nidulans. PMID- 4156016 TI - Coexistence of raynaud's phenomenon and chronic active hepatitis with hepatitis B antigen. PMID- 4156017 TI - Cost containment: The buyer's nightmare. PMID- 4156018 TI - Opinion polls provide valuable feedback: ask the patient. PMID- 4156019 TI - Provocative approaches to materiel management. PMID- 4156020 TI - The art and science of materiel management. PMID- 4156021 TI - Editorial: Humanizing patient care. PMID- 4156022 TI - The trick of materiel management. PMID- 4156023 TI - A dissenting opinion: Miller vs. Unity Hospital. PMID- 4156024 TI - Location of NADH-oxidase activity in fractions of Tritrichomanas foetus homogenate. PMID- 4156025 TI - Effects of anti-T cell (theta) and anti-B cell (beta) serum on the immune response in mice. PMID- 4156026 TI - Activity of the reticuloendothelial system and the antibody response. III. The fate of type III pneumococcal polysaccharide and the antibody response. PMID- 4156027 TI - Immunological disease induced by injecting F1 lymphoid cells into certain parental strains. PMID- 4156028 TI - The action of some sympathomimetic amines on the neuromuscular junction. PMID- 4156029 TI - Simple chemical synthesis of a specific effector for the affinity chromatography of nicotinamide adenine dinucleotide phosphate-dependent dehydrogenases. PMID- 4156031 TI - [Report on the seminar of American Operating Room Nurses, Association]. PMID- 4156030 TI - Regulation of gene expression in mammalian cells. PMID- 4156032 TI - Problems of cryptorchidism. PMID- 4156033 TI - Evaluation of gonadal function in childhood and adolescence. PMID- 4156034 TI - Some properties of glutamine synthetase from baker's yeast. PMID- 4156035 TI - Succinate- and NADH oxidase systems of Escherichia coli membrane vesicles. Mechanism of selective inhibition of the systems by zinc ions. PMID- 4156036 TI - Separation and analysis of psychopharmacologic drugs by high efficiency liquid chromatography. PMID- 4156037 TI - An evaluation of low voltage counterimmunoelectrophoresis for the detection of hepatitis-B antigen (HB Ag). AB - A newly available low voltage counterimmunoelectrophoresis (CIEP) system for the detection of HB Ag (Hapindex, Ortho Diagnostics) was compared with a conventional CIEP method used at this laboratory. A total of 1216 sera were tested. The Hapindex system was found to be at least as sensitive as the conventional CIEP. No false positives were found in this series. The elimination of any preparative work makes the Hapindex system particularly suitable for laboratories not testing large numbers of sera for HB Ag. It also eliminates many of the contamination hazards inherent in the conventional method. PMID- 4156038 TI - The cold pressor response in liver cirrhosis. PMID- 4156039 TI - Effect of beta-alanine on glucose and fructose catabolism in Drosophila melanogaster with notes on beta-aminoisobutyric and gamma-aminobutyric acids. PMID- 4156040 TI - Estimation of effect of drugs on the nasal circulation. PMID- 4156042 TI - Inappropriate directions in the evolution of the physicians assistants. PMID- 4156041 TI - Steroidogenesis in vitro by the ovarian tissue of the domestic fowl (Gallus domesticus). PMID- 4156043 TI - Psychophysiology of pain: diagnostic and therapeutic implications. PMID- 4156044 TI - Physician extenders: divergent views and implications for the future. PMID- 4156045 TI - The computer in family practice. PMID- 4156046 TI - Toward consumer-oriented health care. PMID- 4156047 TI - Letters to the editor: Psychogenic backache. PMID- 4156049 TI - Changes in conduction velocity within a nerve net. PMID- 4156048 TI - Cerebral energy reserves and glycolysis in neural tissue of 6-aminonicotinamide treated mice. PMID- 4156050 TI - Isolation of hydrophobic proteins binding neurotransmitter amino acids: Gamma aminobutyric acid receptor of the shrimp muscle. PMID- 4156051 TI - Subunit structure and kinetic properties of 4-aminobutyrate-2-ketoglutarate transaminase purified from mouse brain. PMID- 4156053 TI - Metabolic compartmentation of glutamate associated with the formation of gamma aminobutyrate. PMID- 4156052 TI - L-glutamic acid decarboxylase in non-neural tissues of the mouse. PMID- 4156054 TI - Metabolic compartmentation in the brain: metabolism of a tricarboxylic acid cycle intermediate, (1,4-14C)succinate, after intracerebral administration. PMID- 4156055 TI - Membrane permeability change during inhibitory transmitter action in crayfish stretch receptor cell. PMID- 4156056 TI - Occupational medicine's new resource. PMID- 4156057 TI - Laser effect on vital oral tissues: a preliminary investigation. PMID- 4156058 TI - Half-life of diphenylpyraline in man. PMID- 4156059 TI - Spectrofluorodensitometric determination of flurazepam and its major metabolites in blood. PMID- 4156060 TI - GLC determination of propranolol, other beta-blocking drugs, and metabolites in biological fluids and tissues. PMID- 4156061 TI - Testicular carnitine acetyltransferase activity and serum testosterone levels in developing and cryptorchid rats. PMID- 4156062 TI - [A new nursing seminar. Internal medicine]. PMID- 4156064 TI - [Recommendations of the 29th All-Union Congress of Surgeons]. PMID- 4156063 TI - [Use of salazopyridazine in sphincter-preserving operations for nonspecific ulcerative colitis]. PMID- 4156066 TI - Induction of lethal graft versus host disease in rats by spleen grafting. PMID- 4156065 TI - [Organization and prospects for the development of the surgical service in the USSR; a report to the 29th All-Union Congress of Surgeons]. PMID- 4156067 TI - General principles of assays for adenylate cyclase and guanylate cyclase activity. PMID- 4156068 TI - Preparation of vertebrate photoreceptor membranes for study of adenylate cyclase, guanylate cyclase, and cyclic nucleotide phosphodiesterase. PMID- 4156069 TI - Preparation and characterization of guanylate cyclase from bovine lung. PMID- 4156070 TI - Guanylate cyclase from sperm of the sea urchin, Strongylocentrotus purpuratus. PMID- 4156071 TI - Guanylate cyclase in human platelets. PMID- 4156072 TI - Separation and purification of cyclic nucleotides by alumina column chromatography. PMID- 4156073 TI - Separation and purification of cyclic nucleotides by ion-exchange resin column chromatography. PMID- 4156074 TI - [Carbon dioxide fixation on 3-carbon acceptors in the obligate chemoautotroph Thiobacillus thiooxidans]. PMID- 4156075 TI - [Study of the activity of glutamine synthetase from the food yeast Candida tropicalis in the presence of magnesium, manganese and other cations]. PMID- 4156076 TI - Adverse Drug Reactions Advisory Committee report for 1973. PMID- 4156077 TI - [The effect of beta receptor blockaders on shifts in the ST and T leads of the electrocardiogram. Differential diagnostic possibilities for the differentiation between functional and organic diseases]. PMID- 4156078 TI - [Treatment of trigeminal neuralgia with beta receptor blockaders]. PMID- 4156079 TI - [International implications of fluoridation as a collective prevention of dental caries]. PMID- 4156080 TI - MMPI correlates of localized cerebral lesions. PMID- 4156081 TI - [Effect of beta-adrenergic blockage on the electrocardiographic exercise test in patients with angina pectoris]. PMID- 4156082 TI - [Clinical and experimental transplantation of the adrenals]. PMID- 4156083 TI - [The role of enzymatic disorders in carbohydrate and nucleotide metabolism in the pathogenesis of diabetes mellitus]. PMID- 4156084 TI - Phenelzine in phobic states. PMID- 4156085 TI - [Immunological and pathological aspects of immunopneumopathy produced in mice by pneumotoxic sera (author's transl)]. PMID- 4156086 TI - [Arrhythmias and the pre-excitation syndrome]. PMID- 4156087 TI - [Adrenergic beta blocking agents in clinical medicine: hopes and disappointments]. PMID- 4156088 TI - The oral health of children of dentists. PMID- 4156089 TI - Fissure sealing with Nuva-Seal in a public health program for Danish schoolchildren after 12 months' observation. PMID- 4156090 TI - Histochemistry of the epithelium in excisional palatal wounds of guinea pigs. PMID- 4156091 TI - Enzyme activities of the perfused ex-vivo porcine liver: importance of a physiological perfusate. PMID- 4156092 TI - [Daily working conditions 1974]. PMID- 4156093 TI - [Council of Representatives meeting]. PMID- 4156094 TI - [Students discuss the future of the profession in London]. PMID- 4156095 TI - [Older member,s anniversary wish: why not have a special meeting with representatives]. PMID- 4156096 TI - [Jaw fractures. Treatment of maxillofacial fractures]. PMID- 4156097 TI - [Effect of sorbitol-containing chewing gum on the occurrence of dental caries, plaque, and gingivitis]. PMID- 4156098 TI - Effects of alpha and beta receptor stimulating and blocking agents on experimental disseminated intravascular coagulation. AB - In this experimental study on rabbits, we compare the haemostatic and histological changes observed in animals with disseminated intravascular coagulation (DIC) induced by thrombin perfusion (100 u/kg/hr during 3 hours) with or without preventive administration of alpha and beta receptor stimulating or blocking agents. Both alpha and beta receptor stimulating agents enhance the disorders induced by thrombin alone, while alpha or beta blocking agents reduce them. This favourable action is still more pronounced with the combination of these two last types of drugs. The modifications observed appear to be related to changes in platelet function. PMID- 4156099 TI - Testicular nondescent versus testicular agenesis: importance of diagnosis and correct surgical management. PMID- 4156100 TI - Duplication of penis. PMID- 4156101 TI - [Motor-evacuation function of the gastrointestinal tract in external intestinal fistulas in experiments]. PMID- 4156102 TI - [Selection of intravenous anesthesia method in emergency surgery]. PMID- 4156103 TI - [Regional conferences and seminars of specialists of the RSFSR]. PMID- 4156105 TI - Reference materials and methods in clinical chemistry. Report of a Discussion Group Meeting held on the occasion of the 1st European Congress of Clinical Chemistry. Munich, 23rd April 1974. PMID- 4156104 TI - [A change in the concentrations of RNA, DNA and nicotinamide coenzymes in the tissues of rabbits undergoing treatment with alkylating agents for an experimental rheumatoid-arthritic process]. PMID- 4156107 TI - [Cognitive performance changes in brain damaged children. Application of classification studies in clinical-psychological diagnostics]. PMID- 4156106 TI - Problems of insecticide resistance. PMID- 4156108 TI - [Effect of beta receptor blockaders on energy metabolism of the myocardium in experimental hyperthyroidism]. PMID- 4156109 TI - [Determination of action begin and action duration of various beta-sympatholytic agents]. PMID- 4156110 TI - [Comparative studies on the determination of increased thrombocyte aggreggation. Report on "two workshops" in Frankfurt/Main]. PMID- 4156111 TI - [Methods and clinical experiences with a thin-layer chromatography procedure for the detection of drugs in human urine (Drug-screen)]. PMID- 4156112 TI - [Hemodynamic effect of beta receptor blockaders in arterial hypertension]. PMID- 4156113 TI - [Renin, angiotensin II, catecholamines and blood pressure in healthy subjects and in patients with essential hypertension prior and following beta-blockade]. PMID- 4156114 TI - [Antihypertensive effect of beta-blockaders]. PMID- 4156115 TI - [Therapy of essential hypertension using a new beta-receptor blockader (timolol maleate) combined with hydrochlorothiazide]. PMID- 4156116 TI - [Pharmacokinetics of a new beta-receptor blockader (terbuclomin) in kidney failure]. PMID- 4156117 TI - [Enzyme excretion in decreased kidney function]. PMID- 4156118 TI - [Significance of the beta-receptor system for the Euler-Liljestrand mechanism]. PMID- 4156119 TI - [Studies on the activity of NADP-linked dehydrogenases in porcine adipose tissue. 2. Comparison of enzyme activity in adipose tissue, liver and muscle and the influence of body weight, fasting, refeeding and sex on enzyme activity in adipose tissue]. PMID- 4156120 TI - [Significance of ophthalmological symptoms in early diagnosis and treatment of diabetes mellitus]. PMID- 4156121 TI - [Absorption, distribution and excretion of Co58-labelled vitamin B 12 during neoplastic process in the irradiated and non-irradiated body (experimental study)]. PMID- 4156123 TI - [Complex evaluation of epidemiological state of tuberculosis among children]. PMID- 4156122 TI - [Study of the effect of biological pastes on the course of experimental traumatic pulpitis]. PMID- 4156124 TI - [Amino acid composition of human milk at different periods of lactation and effect on it of hedge nettle extract administered in the early puerperal]. PMID- 4156125 TI - [Characteristics of leukocytic blood formula and erythrocyte count in healthy children aged 3-7 years under conditions of high altitude in Kirghizia]. PMID- 4156126 TI - [Hepatic echinococcosis]. PMID- 4156127 TI - [Isolation of arboviruses from birds in the areas of mass flight]. PMID- 4156128 TI - [Certain indicators of health and work capacity of school children attending a rural boarding school]. PMID- 4156129 TI - [Immunobiological reactivity of the body according to "skin autoflora" test]. PMID- 4156130 TI - [Intensity of erythropoiesis and erythrocyte survival in the blood of children under conditions of high and low altitude in Kirghizia]. PMID- 4156131 TI - [Incidence and course of acute and severe pneumonia according to materials of the Urban Hospital No. 3 in Frunze]. PMID- 4156132 TI - [Osteolysis of the distal phalanges of the fingers in scleroderma]. PMID- 4156133 TI - [Development of pharmacies during the 50 years of the Kirghiz SSR]. PMID- 4156134 TI - [Internal biliary fistulas in cholelithiasis]. PMID- 4156135 TI - [Case of intravital diagnosis of dissecting aneurysm of the abdominal aorta]. PMID- 4156136 TI - [Atrial trepidation developing into fibrillation]. PMID- 4156137 TI - [Bacterial sensitization in hemorrhagic vasculitis in children]. PMID- 4156138 TI - [Preparation of Q-fever antigen by Frigen 113 extraction (author's transl)]. PMID- 4156140 TI - [Natural foci and epidemiological characteristics of pseudotuberculosis on Sakhalin and the Kurile Islands]. PMID- 4156139 TI - [Use of methisazone for prevention of postvaccinal complications after smallpox vaccination]. PMID- 4156141 TI - [Study of the bacterial flora in children with acute respiratory diseases]. PMID- 4156142 TI - [Sudden cessation of psychotropic drugs]. PMID- 4156143 TI - Insulin and fat metabolism. PMID- 4156144 TI - Conditioning in the prediction of drug withdrawal effects in chronic schizophrenic patients. PMID- 4156145 TI - Bacterial flora of the normal conjunctiva. I. Topographical distribution. PMID- 4156146 TI - Activity of gamma-glutamyl-transpeptidase (GGTP) and leucyl-arylamidase (LAP) in the renal tubule during stop flow in dogs, in various ischemic states. PMID- 4156147 TI - [Evaluation of systematic desensitization in phobic patients]. PMID- 4156148 TI - [Injectable temesta, anxiety and distress]. PMID- 4156149 TI - [Double-blind trial treatment of anxiety with b 5833]. PMID- 4156150 TI - [A new benzodiazepine screened in a parallel double-blind test]. PMID- 4156151 TI - Urinary screening for drugs in a hospital for the mentally subnormal. PMID- 4156152 TI - An electron microscopic study of influenza virus reproductive cycle in chick embryo cells with selective inhibition of host cell macromolecular synthesis. PMID- 4156153 TI - Strong inhibition of transfection by critical low concentration of diethylaminoethyl-dextran. PMID- 4156154 TI - Thymidine kinase induction in mouse embryo cells by polyoma virus. II. Effect of 5-fluorouracil. PMID- 4156155 TI - Ribonuclease activity tightly bound to ribosome-like structures isolated from avian myeloblastosis virus. PMID- 4156156 TI - Adaptation of herpes simplex virus type 1 to supraoptimal temperature. II. Immunofluorescent and cytological study of virus-infected cells, adapted and non adapted to 40 degrees C. PMID- 4156157 TI - Behaviour of two herpes simplex virus strains of genital and non-genital origin carried through serial passages in WI-38 cells. PMID- 4156158 TI - Pathogenicity of mengo virus to mice. I. Virological studies. PMID- 4156159 TI - Aetiology of phlebotomus fever in Ashkhabad studied in retrospect. PMID- 4156160 TI - Rickettsial plaques in mosquito cell monolayers. PMID- 4156161 TI - Professor Frantisek Patocka--Septuagenarian. PMID- 4156162 TI - Regulation and suppression of graft-versus-host reaction. PMID- 4156163 TI - [New problems in tolerance induction]. PMID- 4156165 TI - [Age-related dynamics of NAD.H2-tetrazolium reductase activity in the neuroglial cells of the cat cerebral cortex]. PMID- 4156164 TI - [Lactic acidosis, hypoglycemia and hepatomegaly due to hereditary defect in hepatic fructose-1, 6-diphosphatase]. PMID- 4156166 TI - [Nicotinamide diaphorases and pentose cycle enzymes in the tooth germ of the human embryo]. PMID- 4156167 TI - Lipogenesis in rat and guinea-pig isolated epididymal fat-cells. AB - Fat-cells were prepared from rat and guinea-pig epididymal adipose tissue and compared on the basis of the intracellular distributions and activities of enzymes and with respect to their utilization of various U-(14)C-labelled substrates for lipogenesis. 1. Compared with the rat, guinea-pig extramitochondrial enzyme activities differed in that aconitate hydratase, alanine aminotransferase, ATP-citrate lyase, lactate dehydrogenase, NAD-malate dehydrogenase, NADP-malate dehydrogenase and phosphoenolpyruvate carboxykinase activities were appreciably lower, whereas aspartate aminotransferase, glucose 6 phosphate dehydrogenase, NADP-isocitrate dehydrogenase and 6-phosphogluconate dehydrogenase activities were appreciably higher. Mitochondrial activities of citrate synthase, NADP-isocitrate dehydrogenase and pyruvate carboxylase were appreciably lower, whereas mitochondrial activities of aspartate aminotransferase, glutamate dehydrogenase, NAD-malate dehydrogenase and phosphoenolpyruvate carboxykinase were higher in the guinea pig compared with the rat. 2. In general guinea-pig fat-cells incorporated acetate and lactate into fatty acids more readily than rat fat-cells, whereas rat fat-cells incorporated glucose and pyruvate more readily than guinea-pig fat-cells. 3. Acetate stimulated the incorporation of glucose into fatty acids in rat fat-cells, but had no appreciable effect upon this process in guinea-pig fat-cells. Acetate greatly decreased the incorporation of lactate into fatty acids in cells from both species. 4. Lactate/pyruvate ratios produced by incubation of guinea-pig cells with glucose+insulin were very low compared with those found with rat cells under the same conditions. 5. With glucose (+insulin) or with glucose+acetate (+insulin) as substrates guinea-pig cells produced enough NADPH by the hexose monophosphate pathway to satisfy the NADPH requirements of lipogenesis. In rat fat-cells under the same conditions, hexose monophosphate-pathway NADPH provision was not sufficient to meet the requirements of lipogenesis. 6. These results are discussed, particularly in relationship to the disposition of cytosolic reducing equivalents in the cells. PMID- 4156168 TI - Microbial oxidation of amines. Partial purification of a trimethylamine mono oxygenase from Pseudomonas aminovorans and its role in growth on trimethylamine. AB - 1. A mono-oxygenase, which oxidizes trimethylamine and other tertiary amines bearing methyl or ethyl groups, was partially purified sixfold from Pseudomonas aminovorans grown on trimethylamine as sole carbon source. 2. The preferred electron donor was NADPH. The enzyme had a pH optimum of 8.0-9.4 for trimethylamine oxidation, and 8.8-9.2 for dimethylamine oxidation. 3. The oxidation product of trimethylamine was shown to be trimethylamine N-oxide. Other tertiary amines were probably also converted into N-oxides. 4. The enzyme also oxidized secondary amines. 5. The oxidation of trimethylamine was only slightly inhibited by CO and not at all by KCN or proadifen hydrochloride (SKF 525-A), but was inhibited by trimethylsulphonium chloride, tetramethylammonium chloride, 2,4 dichloro-6-phenylphenoxyethylamine (Lilly 53325) and its NN-diethyl derivative (Lilly 18947). 6. The oxidation of dimethylamine showed a similar response to inhibitors and a parallel loss in activity on heating at 35 degrees C. 7. The activities of the trimethylamine mono-oxygenase, trimethylamine N-oxide demethylase and the secondary-amine mono-oxygenase increased severalfold during adaptation of succinate-grown bacteria to growth on trimethylamine, and the trimethylamine mono-oxygenase was the first enzyme to show an increase in activity. It is concluded that all three enzymes are involved in growth on trimethylamine by this organism. PMID- 4156169 TI - Microbial metabolism of the pyridine ring. The hydroxylation of 4-hydroxypyridine to pyridine-3,4-diol (3,4-dihydroxypyridine) by 4-hydroxypyridine-3-hydroxylase. AB - 1. The first metabolic step in the biodegradation of 4-hydroxypyridine by an Agrobacterium sp. was hydroxylation to form pyridine-3,4-diol. 2. Extracts required 1mol of O(2) and 1mol of NADH or NADPH for the conversion of 4 hydroxypyridine into pyridine-3,4-diol, suggesting that the enzyme responsible, 4 hydroxypyridine-3-hydroxylase, was a mixed function mono-oxygenase. 3. After treatment with acidic (NH(4))(2)SO(4) the enzyme required FAD for activity; FMN and riboflavin would not substitute for FAD. 4. The rate of anaerobic reduction of FAD by NAD(P)H was increased more than tenfold in the presence of 4 hydroxypyridine, suggesting that the mechanism of hydroxylation was similar to that of other aromatic hydroxylases which are of the mono-oxygenase type. 5. The partially purified enzyme was extremely specific for its heterocyclic substrate but would utilize either NADH or NADPH. 6. 4-Hydroxypyridine-3-hydroxylase was strongly inhibited by high substrate concentration (above 0.5mm) especially below pH7.5. 8. The inflexion at pH8.4 in a pK(m) versus pH plot, together with strong inhibition by p-chloromercuribenzoate, suggested a role for thiol groups in substrate binding. PMID- 4156170 TI - The isolation and subfractionation of plasma membrane from the cellular slime mould Dictyostelium discoideum. AB - A procedure for the isolation and separation of three different subfractions of plasma membrane from the cellular slime mould Dictyostelium discoideum is described. The cells were disrupted by freeze-thawing in liquid N(2) and plasma membranes were purified by equilibrium centrifugation in a sucrose gradient. The cell surface was labelled with radioactive iodide by using the lactoperoxidase iodination method. Alkaline phosphatase was identified as a plasma-membrane marker by its co-distribution with [(125)I]iodide. 5'-Nucleotidase, which has been widely described as a plasma-membrane marker enzyme in mammalian tissues, was not localized to any marked extent in D. discoideum plasma membrane. The isolated plasma membranes showed a 24-fold enrichment of alkaline phosphatase specific activity relative to the homogenate and a yield of 50% of the total plasma membranes. Determination of succinate dehydrogenase and NADPH-cytochrome c reductase activities indicated that the preparation contained 2% of the total mitochondria and 3% of the endoplasmic reticulum. When the plasma-membrane preparation was further disrupted in a tight-fitting homogenizer, three plasma membrane subfractions of different densities were obtained by isopycnic centrifugation. The enrichment of alkaline phosphatase was greatest in the subfraction with the lowest density. This fraction was enriched 36-fold relative to the homogenate and contained 19% of the total alkaline phosphatase activity but only 0.08% of the succinate dehydrogenase activity and 0.34% of the NADPH cytochrome c reductase activity. Electron microscopy of this fraction showed it to consist of smooth membrane vesicles with no recognizable contaminants. PMID- 4156171 TI - Comparison of the amino acid sequences of the variable regions of light chains derived from two homogeneous rabbit anti-pneumococcal antibodies. AB - The amino acid sequence of the N-terminal 139 residues of the L (light) chain derived from a homogeneous rabbit antibody to type III pneumococci was determined. This L chain, designated BS-5, exhibits a greater degree of homology with the basic sequence of human kappa chains of subgroup I (72%) than with subgroups II and III. L-chain BS-5 differs from another L chain (BS-1), also derived from an antibody to type III pneumococci (Jaton, 1974), by eight amino acid residues, even though the chains are identical within the N-terminal 30 residues. Six of these eight substitutions are located within the three hypervariable sections of the variable half: Asn/Ser in position 31, Glu/Ala in position 55, Asx/Thr, Thr/Gly, Thr/Gly and Val/Tyr in positions 92, 94, 96 and 97 respectively. The two anti-pneumococcal L chains BS-1 and BS-5 are much more similar to each other than to an anti-azobenzoate L chain (Appella et al., 1973), from which they differ by 30 and 29 residues respectively. Of these interchanges 13-15 are confined to the three hypervariable sections, and 11 occur within the N terminal 27 positions. The three chains have an identical sequence from residue 98 to residue 139, except for a possible inversion of two residues in positions 130-131 of the anti-azobenzoate chain. PMID- 4156172 TI - Regulation of ornithine decarboxylase activity by putrescine and spermidine in rat liver. PMID- 4156173 TI - Liver microsomal electron transport systems. III. The involvement of cytochrome b5 in the NADPH-supported cytochrome P-450-dependent hydroxylation of chlorobenzene. PMID- 4156174 TI - Microsomal (muS)1 lipid peroxidation, drug oxidations and chemiluminescence (CL): mechanisms. PMID- 4156175 TI - Metabolic differences between the arteries of atheroscierotic susceptible and resistant pigeons. PMID- 4156176 TI - Genetic variation in histidine ammonia-lyase activity in the mouse. PMID- 4156177 TI - Neuro-pharmacological studies on SB 5833, a new psychotherapeutic agent of the benzodiazepine class. PMID- 4156178 TI - A preliminary double-blind study with SB 5833 (camazepam), a new benzodiazepine derivative. PMID- 4156179 TI - Clinical testing of dicalcium phosphate supplemented sweets. (2). Caries prevalence in subjects aged 3 to 14 years following a maximum of three years' exposure to the sweets. PMID- 4156180 TI - Clinical testing of dicalcium phosphate supplemented sweets. (1). 3-year caries incidence in subjects aged 11 to 15 years. PMID- 4156181 TI - The effect of certain drugs on amphetamine-induced stereotyped behavior and brain amphetamine levels in the rat. PMID- 4156182 TI - The effect of a polychlorinated biphenyl (Aroclor 1254) on liver microsomal enzymes in the male rat. PMID- 4156183 TI - Patterns of admission in schizophrenia. PMID- 4156184 TI - [Clomiphene, nidation and fetus survival]. PMID- 4156185 TI - [Restorative therapeutic efficiency of mouse hematopoietic stem cells: modification by adjunction of thymic cells]. PMID- 4156186 TI - [Action of 3 beta adrenolytics on plasma renin hyperactivity induced by isoprenaline in the anesthtized dog. Contribution to its mechanism of action]. PMID- 4156187 TI - [Alpha-adrenergic blocking properties of metaraminol in the rat]. PMID- 4156188 TI - Methods for studying lipid-protein interactions. PMID- 4156189 TI - Genetic control of the immune response of mice to type III pneumococcal polysaccharide. PMID- 4156190 TI - Allogeneic interactions in the immune response and tolerance. I. The allogeneic effect in unprimed rats and mice. PMID- 4156191 TI - Cross-reactivity patterns of mouse lymphocytes sensitized against the major histocompatibility complex using a graft-versus-host assay. PMID- 4156192 TI - Allotype levels in normal and allotype suppressed mice after allogeneic stimulation. PMID- 4156193 TI - In vivo effects of antithymocyte serum on the homing patterns and graft-versus host reactivity of murine splenic lymphocytes. PMID- 4156194 TI - Immune restoration of mice immunosuppressed by a graft-vs.-host reaction. PMID- 4156195 TI - Local graft-versus-host reaction suppressed by immuno-blocking antibody secreted by antibody-forming cells transferred with the graft. PMID- 4156196 TI - Clinical trial of CDP-choline as a medicament for acute pancreatitis and its relation to pancreas and liver damage in acute pancreatitis. PMID- 4156197 TI - A critical review of the field application of a mathematical model of malaria eradication. AB - A malaria control field research trial in northern Nigeria was planned with the aid of a computer simulation based on Macdonald's mathematical model of malaria epidemiology. Antimalaria attack was based on a combination of mass drug administration (chloroquine and pyrimethamine) and DDT house spraying. The observed results were at great variance with the predictions of the model. The causes of these discrepancies included inadequate estimation of the model's basic variables, and overestimation, in planning the simulation, of the effects of the attack measures and of the degree of perfection attainable by their application. The discrepancies were to a great extent also due to deficiencies in the model. An analysis is made of those considered to be the most important. It is concluded that research efforts should be encouraged to increase our knowledge of the basic epidemiological factors, their variation and correlations, and to formulate more realistic and useful theoretical models. PMID- 4156198 TI - A comparison of the activities of the beta-adrenoceptor agonists MJ9184-1 AND (- )-ISOPRENALINE IN GUINEA-PIG AND CAT PREPARATIONS. PMID- 4156199 TI - Activities of some glycolytic enzymes in the major salivary glands of some laboratory animals. PMID- 4156200 TI - Insulation of furs in water. PMID- 4156201 TI - Bile pigments in the blood serum of fish from the family Cottidae. PMID- 4156202 TI - Effect of hypothalamic extracts on prolactin secretion in the goldfish, Carassius auratus L. PMID- 4156203 TI - The effect of repeated stimulation on the escape reflex and the acetylcholinesterase activity in different parts of the central nervous system in the crayfish (Pacifastacus leniusculus and Astacus astacus). PMID- 4156204 TI - Organic material and calories in the egg of the brown pelican, Pelecanus occidentalis. PMID- 4156205 TI - Serological differentiation of two species of Taterillus (Rodentia, Gerbillidae) from Senegal: T. gracilis (Thomas, 1892) and T. pygargus (Cuvier, 1832). PMID- 4156206 TI - Cellular DNA content of the Mollusca. PMID- 4156207 TI - Blood glucose in crayfish--I. Variations associated with molting. PMID- 4156208 TI - Depolarization-induced change in the enzymatic radio-iodination of a protein of the internal surface of the squid giant, axon membrane. PMID- 4156209 TI - Gas exchange and metabolism in the Sirenidae (Amphibia: Caudata)--I. Oxygen consumption of submerged sirenids as a function of body size and respiratory surface area. PMID- 4156210 TI - A study of the adaptation of marine organisms to changing salinities with special reference to the shore crab Carcinus maenas (L.). PMID- 4156211 TI - Calcium transport by subcellular fractions of rat, dog and monkey brains. PMID- 4156212 TI - Digestive enzymes in the salivary gland and midgut of the bug Stenotus binotatus. PMID- 4156213 TI - Carbon dioxide tension and pH of the blood of the lizard Sauromalus obesus at different temperatures. PMID- 4156214 TI - Myoglobin concentration in the chicken, especially in the gizzard (a biochemical, light and electron microscopic study). PMID- 4156215 TI - Temporal changes in amino acid catabolism during arousal from hibernation in the golden-mantled ground squirrel. PMID- 4156216 TI - Lack of influence of small ligands on the alkaline dissociation of Archachatina marginata haemocyanin and absence of co-operativity in the oxygenation. PMID- 4156217 TI - The effect of some amino acids on carbohydrate uptake by Trypanosoma lewisi. PMID- 4156218 TI - Chemoreception and the role of proteins: a comparative study. PMID- 4156219 TI - Organ culture of Amphiuma means liver: control of glycogen content. PMID- 4156220 TI - The distribution of the digestive enzymes in the gut of the polychaete Neanthes virens (Sars). PMID- 4156221 TI - Standard metabolism and body temperature of perameloid marsupials from different environments. PMID- 4156222 TI - Thermoregulation in perameloid marsupials from different environments. PMID- 4156223 TI - Water metabolism in perameloid marsupials from different environments. PMID- 4156224 TI - Seasonal and age variation in the metabolism of the common frog, Rana temporaria L. in northern Finland. PMID- 4156225 TI - Effects of mammalian and host gonadotropins on the ovaries and oviducts of female Texas horned lizards, Phrynosoma cornutum. PMID- 4156226 TI - Evolution in ground squirrels--I. Transferrins in holarctic populations of Spermophilus. PMID- 4156227 TI - Hydroxyproline content of the tadpole tail in response to hypothyroidism. PMID- 4156228 TI - Excitation-secretion coupling in the release of catecholamines from the in vitro frog adrenal: effects of K+, Ca2+, hypertonicity, Na+ and Ni2+. PMID- 4156229 TI - Seasonal and sex-bound variation in the carbohydrate metabolism of the liver of the whitefish. PMID- 4156230 TI - Exogenous 14C-urea distribution in Chimaeras. PMID- 4156231 TI - Exogenous 14C-urea distribution in rajiformes and teleosts. PMID- 4156232 TI - Comparative water relations of five species of spiders from different habitats. PMID- 4156233 TI - Distinct components of neutral amino acid transport in chick small intestine. PMID- 4156234 TI - The crustacean cuticle--I. Studies on the composition of the cuticle. PMID- 4156235 TI - Osmoregulation in the adult water boatman, Corisella edulis champion. PMID- 4156236 TI - Differential in rectal and chest muscle temperature during arousal in Eptesicus fuscus and Myotis sodalis (Chiroptera: Vespertilionidae). PMID- 4156237 TI - The effect of crustacean eye stalk extract on the endogenous respiration of selected mammalian tissues. PMID- 4156238 TI - The effect of salinity and sex on the respiration rates of excised gills of the blue crab, Callinectes sapidus. PMID- 4156239 TI - Studies on the mechanism of uptake of D-glucose by Tetrahymena pyriformis GL. PMID- 4156240 TI - [Glyconeogenesis from glycine 14C in tench during asphyxia]. PMID- 4156241 TI - Adaptations in the water economy of some anuran amphibia. PMID- 4156242 TI - Single unit discrimination of fish odours released by char (Salmo alpinus L.) populations. PMID- 4156243 TI - Oxygen consumption in relation to environmental oxygen concentrations in the ampullariid snail Marisa cornuarietis (L.). PMID- 4156244 TI - Surface activity of various fractions of rabbit lung lavage fluid. PMID- 4156245 TI - Water content of the salt glands and other avian tissues. PMID- 4156246 TI - Effect of glucose and other carbohydrates on the toad's glomerular pressure. PMID- 4156247 TI - The eco-physiological significance of the circulatory mechanics of Lymnaea stagnalis L. PMID- 4156248 TI - The development of thermoregulation and thyroid function in the marsupial Macropus eugenii (Desmarest). PMID- 4156249 TI - Erythrocytic ouabain-sensitive and ouabain-insensitive adenosine triphosphatase in various mammalian species;. PMID- 4156250 TI - Contractility of the in situ hibernating marmot ventricle. PMID- 4156251 TI - Circadian rhythm of plasma prolactin, growth hormone, glucose and free fatty acid in juvenile kokanee salmon, Oncorhynchus nerka. PMID- 4156252 TI - Water metabolism of two marsupials--the brush-tailed possum, Trichosurus vulpecula and the rock-wallaby, Petrogale inornata in the wild. PMID- 4156253 TI - The effect of essential fatty acids deficiency on the nitrogen metabolism of rats. PMID- 4156254 TI - Biochemical studies on some aspects of protein metabolism in vitamin-D deficient rats. PMID- 4156255 TI - Comparative biochemical studies of osmo-regulation in Sipunclul--I; Steady-state characteristics of two sipunculids in full-strength sea water. PMID- 4156256 TI - Anoxia tolerance in two species of toads, Bufo valliceps and Bufo woodhousei. PMID- 4156257 TI - Molecular and ultrastructural characterization of the egg capsule of the leech Erpobdella octoculata L. PMID- 4156258 TI - Movement of cholesterol and beta-sitosterol across the intestine of Ascaris suum. PMID- 4156259 TI - Movement of triglycerides and monoglycerides across the intestine of Ascaris suum. PMID- 4156260 TI - The electrogenic sodium pump and membrane potential of identified neurones in Helix aspersa. PMID- 4156261 TI - On the electrical gradient across the gill of the sea water-adapted eel. PMID- 4156262 TI - Cardiac response to diving in wild ducks. PMID- 4156263 TI - Effects of prolonged diving anoxia on the turtle, Pseudemys scripta elegans. PMID- 4156264 TI - The effects of nerve transection in walking legs of lobster on acetylcholine, acetylcholinesterase, choline acetyltransferase, adenosine triphosphatase and protein composition. PMID- 4156265 TI - Effects of cytochalasin B and other agents of insulin secretion from Saurian islets. PMID- 4156266 TI - Osmotic responses of spiny dogfish (Squalus acanthias L.) embryos to temperature and salinity stress. PMID- 4156267 TI - Body temperatures in the Tasmanian devil, Sarcophilus harrisii (Harsupialia: Dasyuridae). PMID- 4156268 TI - Effects of calcium and magnesium on facilitation of a unitary synaptic potential in neuron R15 of Aplysia. PMID- 4156269 TI - The osmolarity of the fluid secreted by the malpighian tubules of Carausius morosus. PMID- 4156270 TI - The effect of vitamine B6 on alanine transport in turtle intestine. PMID- 4156271 TI - The prandial state and the glycaemic and lipolytic responses of Gallus domesticus to catecholamines and glucagon. PMID- 4156272 TI - Ionic distribution and fluxes in holothurian tissues. PMID- 4156273 TI - Studies on the fibre types of the guinea pig masticatory muscles. PMID- 4156274 TI - A saline transfusion technique for crayfish CNS studies. PMID- 4156275 TI - Volume regulation in Nereis diversicolor--I. The steady state. PMID- 4156276 TI - Volume regulation in Nereis diversicolor--II. The effect of calcium. PMID- 4156277 TI - Volume regulation in Nereis diversicolor--III. Adaptation to a reduced salinity. PMID- 4156278 TI - Vibration detection by the macula neglecta of sharks. PMID- 4156279 TI - Urea, inulin and para-amino-hippuric acid (PAH) excretion by the gills of the eel, Anguilla anguilla L. PMID- 4156280 TI - Salt gland secretion in a mangrove monitor lizard. PMID- 4156281 TI - Bone ash, duodenal 45Ca absorption and calcium-binding protein in chicks fed lathyrogens. PMID- 4156282 TI - Changes in activity in a freshwater clam in response to oxygen concentration. PMID- 4156283 TI - High salinity adaptation of ion transport and epidermal lipids of frog skin. PMID- 4156284 TI - The water balance response of the pelvic "patch" of Bufo punctatus and Bufo boreas;. PMID- 4156285 TI - Interorgan transport of lipids in the purple sea urchin, Strongylocentrotus purpuratus. PMID- 4156287 TI - Responses from tactile receptors in the antenna of the spiny lobster Panulirus japonicus. PMID- 4156286 TI - Diurnal patterns of ammonia release in marine and terrestrial isopods. PMID- 4156288 TI - Erthrocyte glucose-6-phosphate dehydrogenase deficiency-a pharmacogenetic prototype. PMID- 4156289 TI - Double-blind comparison of the respiratory effects of parenteral lorazepam and diazepam in patients with chronic obstructive lung disease. AB - The effects on the respiratory function of two tranquillising drugs, lorazepam and diazepam, have been compared in 20 patients with chronic obstructive lung disease. Both drugs induce a respiratory depression (decrease in tidal volume and minute ventilation with acceleration of the respiratory frequency) with slight respiratory acidosis, but lorazepam causes no significant hypoxemia and has a shorter duration of action than diazepam. Nevertheless, if tranquillisers are indicated in such patients, they have to be used with care. PMID- 4156290 TI - Patient acceptance as a factor in the effectiveness of treatment: an open assessment of potassium clorazepate ('Tranxene') and lorazepam in anxiety. AB - Two new benzodiazepines, potassium clorazepate (15 mg. at night), and lorazepam (1 mg. t.d.s.) were compared in 50 patients presenting with anxiety in general practice. The response to treatment was assessed clinically and for patient acceptance. The single-dose regime of potassium clorazepate was significantly better, both for clinical effectiveness and patient acceptance. In the potassium clorazepate treated group there were significantly fewer side-effects. In particular, sedation was a problem with lorazepam, 6 patients stopping treatment and 8 voluntarily reducing the dose. Only 2 patients stopped treatment because of the sedative effect of potassium clorazepate. The sedative effects also show qualitative differences: in patients who completed the assessment lorazepam caused mainly daylong sedation and potassium clorazepate mid-day sedation, and when asked for their opinion on the value of sedation, only the potassium clorazepate group considered it to be beneficial. PMID- 4156291 TI - Halazepam in anxious outpatients: a controlled study. PMID- 4156292 TI - Effects of continuous infusion of cardiotonic agents on arterial cations and glucose in dogs. PMID- 4156293 TI - Physiologic disposition and metabolic fate of a new anti-inflammatory agent, cis 5-fluro-2-methyl-1-(p-(methylsulfinyl)-benzylidenyl)-indene-3-acetic acid in the rat, dog, rhesus monkey, and man. PMID- 4156294 TI - Seclazone: biotransformation during absorption in the rat, binding in plasma, and disappearance from plasma in the dog. PMID- 4156295 TI - Studies of the fate of metabolites and analogs of probenecid. The significance of metabolic sites, especially lack of ring hydroxylation. PMID- 4156296 TI - Metabolic fate of O2,2'-cyclocytidine. PMID- 4156297 TI - Studies of 9-beta-D-arabinofuranosyladenine in man. PMID- 4156298 TI - A sensitive radioactive assay for hexobarbital hydroxylase in hepatic microsomes. PMID- 4156299 TI - The rate of pentobarbital and acetanilide metabolism by liver microsomes: a function of lipid peroxidation and degradation of cytochrome P-450 heme. PMID- 4156300 TI - New potent modifiers of liver microsomal drug metabolism: 1-arylimidazoles. PMID- 4156301 TI - Isolation and stereochemical identification of a metabolite of naltrexone from human urine. PMID- 4156302 TI - Physiological disposition and urinary metabolites of cyproheptadine in the dog, rat, and cat. PMID- 4156303 TI - The radiosynthesis, percutaneous absorption, and metabolism of the wound-healing agent calcium acexamate in the rat. PMID- 4156304 TI - The in vitro metabolism of 2-hydroxynicotinic acid in human erythrocytes and platelets. PMID- 4156305 TI - Biliary excretion of diazepam in the rat. PMID- 4156306 TI - Metabolism of xenobiotics by the isolated perfused lung. Comparison with in vitro incubations. PMID- 4156307 TI - A comparative study of xenobiotic-metabolizing enzymes in liver and intestine of various animal species. PMID- 4156308 TI - Effects of various barbiturates on hepatic microsomal enzymes. A comparative study. PMID- 4156309 TI - The effect of diazepam on the metabolism of methadone by the liver of methadone dependent rats. PMID- 4156310 TI - Dibenamine impairment of rat hepatic microsomal enzymes and its relation to hepatotoxicity induced by CCl4 and dimethylnitrosamine. PMID- 4156311 TI - Studies on irreversible binding of radioactivity from (14C)halothane to rat hepatic microsomal lipids and protein. PMID- 4156312 TI - The role of ionization in the N-demethylation of some N,N-dimethylamines. PMID- 4156313 TI - The urinary excretion profile of naltrexone and metabolites in man. PMID- 4156314 TI - Pharmacokinetic studies of the disposition of secobarbital in the dog. PMID- 4156315 TI - Fetal hepatic drug metabolism in the nonhuman primate, Macaca arctoides. PMID- 4156316 TI - Hepatic microsomal mixed-function oxidase activity of several marine species from coastal Maine. PMID- 4156317 TI - The interaction of foreign chemical compounds with the glucuronidation of estrogens in vitro. PMID- 4156318 TI - Deuterium and tritium isotope effects on the microsomal N-demethylation of ethylmorphine. PMID- 4156319 TI - Involuntary movements not due to parkinsonism. PMID- 4156320 TI - beta-adrenoreceptor blocking drugs in hypertension. PMID- 4156321 TI - Use of beta-adrenoreceptor blocking drugs in hypertension. PMID- 4156323 TI - Presiding chairman's address to the opening of the Annual Scientific Conference of the Association of the Physicians of East Africa held in Dar es Salaam in June 1974. Medicine and progress. PMID- 4156322 TI - Clinical use of corticosteroids in renal disease. PMID- 4156324 TI - Normal values of plasma gamma-glutamyl transpeptidase in children. PMID- 4156325 TI - The distribution of malate NADP dehydrogenase in adult, fetal and neoplastic tissues of the rat. PMID- 4156326 TI - The use of cell separation techniques and isantibody to host antigens in the treatent of severe combined immunodeficiency disease with HL-A incompatible maternal marrow. PMID- 4156328 TI - [Experiences in activities of a feldsher health center in a machinery plant]. PMID- 4156327 TI - Antilymphocytic antibodies and marrow transplantation. IV. Comparison of the effects of antibody fragments directed against immunoglobulin or lymphocyte antigens on acute secondary disease. PMID- 4156329 TI - [Activities of a feldsher health center in a metallurgy factory]. PMID- 4156330 TI - [Hyperpolarization potentials of surface sections of the cerebral cortex in vivo and in vitro]. PMID- 4156331 TI - [Efferent inhibitory effect of sensory nerves on the heart]. PMID- 4156332 TI - [Problems of treatment with psychopharmacological drugs (author's transl)]. PMID- 4156333 TI - Public relations and patient rights. PMID- 4156335 TI - Physician and trustee must unsure competent medical care. PMID- 4156334 TI - In extended care facilities: reactivation programs cut nursing care costs. PMID- 4156336 TI - Heavy cost for hospitals: the toll of equipment replacement. PMID- 4156337 TI - A new skill for nursing homes: the handling of grievances. PMID- 4156338 TI - Food service: the challenge of cost control. PMID- 4156339 TI - Editorial: Let's get the real culprits. PMID- 4156340 TI - Implications for inservice education: is it legal to reproduce this page? PMID- 4156341 TI - Histochemical studies of the rat epididymis after treatment with alpha chlorohydrin (U-5897). PMID- 4156342 TI - [Effect of benzodiazepine derivatives on rats behavior pattern]. PMID- 4156343 TI - [Spasmolytic effect of piperiodlate on the excised smooth muscles. especially on uterine smooth muscles under the influence of sex hormones]. PMID- 4156344 TI - [Elawox powder, a high percent hydrogen peroxide powder, in the treatment of ulcus cruris]. PMID- 4156345 TI - [Etiology and therapy of the most common congenital defects]. PMID- 4156346 TI - [Side effects of various drugs acting on the eye]. PMID- 4156347 TI - [History of clinical pathology in Hokkaido in the last 50 years]. PMID- 4156348 TI - [Effect of lipids on liver microsomal membranes. (1) Studies of a relationship between delipidation of liver microsomes with the various organic solvents and cytochrome c reductase activity linked to reduced nicotinamide adenine dinucleotide (author's transl)]. PMID- 4156349 TI - Effect of alpha-adrenergic blocking agents on blood cholesterol triglyceride & liver cholesterol biosynthesis in rat. PMID- 4156350 TI - Pharmacology of neural control. PMID- 4156351 TI - Some social and political ramifications of utilizing non-physicians as chemotherapists. PMID- 4156352 TI - [Experience with long acting psychopharmaceutics in psychiatric hospitals]. PMID- 4156353 TI - The treatment of phenothiazine-induced tachycardia by propranolol. PMID- 4156354 TI - Tryptophan-dehydrobutyrine diketopiperazine, a metabolite of Streptomyces spectabilis. PMID- 4156355 TI - A new antibiotic, XK-46. PMID- 4156356 TI - In vitro activity of kitasamycin against gram-positive cocci. PMID- 4156357 TI - In vitro activity of BL-S217, a new cephalosporin antibiotic. PMID- 4156358 TI - Glucose metabolism in Neisseria gonorrhoeae. AB - The metabolism of glucose was examined in several clinical isolates of Neisseria gonorrhoeae. Radiorespirometric studies revealed that growing cells metabolized glucose by a combination on the Entner-Doudoroff and pentose phosphate pathways. A portion of the glyceraldehyde-3-phosphate formed via the Entner-Doudoroff pathway was recycled by conversion to glucose-6-phosphate. Subsequent catabolism of this glucose-6-phosphate by either the Entner-Doudoroff or pentose phosphate pathways yielded CO(2) from the original C6 of glucose. Enzyme analyses confirmed the presence of all enzymes of the Entner-Doudoroff, pentose phosphate, and Embden-Meyerhof-Parnas pathways. There was always a high specific activity of glucose-6-phosphate dehydrogenase (EC 1.1.1.49) relative to that of 6 phosphogluconate dehydrogenase (EC 1.1.1.44). The glucose-6-phosphate dehydrogenase utilized either nicotinamide adenine dinucleotide phosphate or nicotinamide adenine dinucleotide as electron acceptor. Acetate was the only detectable nongaseous end product of glucose metabolism. Following the disappearance of glucose, acetate was metabolized by the tricarboxylic acid cycle as evidenced by the preferential oxidation of [1-(14)C]acetate over that of [2 (14)C]acetate. When an aerobically grown log-phase culture was subjected to anaerobic conditions, lactate and acetate were formed from glucose. Radiorespirometric studies showed that under these conditions, glucose was dissimilated entirely by the Entner-Doudoroff pathway. Further studies determined that this anaerobic dissimilation of glucose was not growth dependent. PMID- 4156359 TI - Regulation of nitrogen fixation in Klebsiella pneumoniae: evidence for a role of glutamine synthetase as a regulator of nitrogenase synthesis. AB - Mutations causing constitutive synthesis of glutamine synthetase (GlnC(-) phenotype) were transferred from Klebsiella aerogenes into Klebsiella pneumoniae by P1-mediated transduction. Such GlnC(-) strains of K. pneumoniae have constitutive levels of glutamine synthetase. Two of three GlnC(-) strains of K. pneumoniae studied, each containing independently isolated mutations that confer the GlnC(-) phenotype, continue to synthesize nitrogenase in the presence of NH(4) (+). One strain, KP5069, produces 30% as much nitrogenase when grown in the presence of 15 mM NH(4) (+) as in its absence. The GlnC(-) phenotype allows the synthesis of nitrogenase to continue under conditions that completely repress nitrogenase synthesis in the wild-type strain. Glutamine auxotrophs of K. pneumoniae, that do not produce catalytically active glutamine synthetase, are unable to synthesize nitrogenase during nitrogen limited growth. Complementation of K. pneumoniae Gln(-) strains by an Escherichia coli episome (F'133) simultaneously restores glutamine synthetase activity and the ability to synthesize nitrogenase. These results indicate a role for glutamine synthetase as a positive control element for nitrogen fixation in K. pneumoniae. PMID- 4156360 TI - Stimulation of transport into Escherichia coli membrane vesicles by internally generated reduced nictotinamide adenine dinucleotide. AB - Membrane vesicles containing internal alcohol dehydrogenase and nicotinamide adenine dinucleotide (NAD) were prepared from Escherichia coli ML308-225. Upon the addition of ethanol, these vesicles respired and transported several amino acids. Transport rates driven by internally generated reduced NAD (NADH) were about 60 to 80% of that stimulated by d-lactate. This transport was inhibited by cyanide and anaerobiosis. Ferricyanide, a nonpermeable electron acceptor, inhibited transport stimulated by external NADH, but not that stimulated by internally generated NADH. PMID- 4156361 TI - Isolation of a trans-dominant histidase-negative mutant of Salmonella typhimurium. AB - A mutation of Salmonella typhimurium was obtained that results in the failure of cells to synthesize the enzyme l-histidine ammonia-lyase (histidase). The mutation mapped within the hutH gene and in merodiploid strains was dominant over the wild-type allele. Extracts from cells bearing the trans-dominant histidase negative allele were shown to contain material that reacts immunologically with antiserum against purified wild-type histidase. It is proposed that the trans dominant allele results in the synthesis of defective histidase subunits that can combine with, and partially inactivate, wild-type histidase subunits. This subunit mixing presumably does occur, as the enzyme synthesized in a hybrid merodiploid strain is abnormally heat sensitive. PMID- 4156362 TI - Ferredoxin from a blue-green alga, Aphanothece sacrum (Suringar) Okada. PMID- 4156363 TI - Primary structure of the N-terminal portion of D-amino acid oxidase. PMID- 4156364 TI - Heart rate feedback and the management of cardiac neurosis. PMID- 4156365 TI - The physician's assistant as a buffer in the delivery of primary care. PMID- 4156366 TI - Parameters in determining the specific activity of the succinate dehydrogenase coenzyme Q10 reductase in mitochondria of leucocytes. PMID- 4156367 TI - Proceedings: Effects of the iontophoretic application of bicuculline on the receptive field properties of simple cells in the visual cortex of the cat. PMID- 4156368 TI - Proceedings: The efferent pathway of the reflex increase in heart rate produced by stimulation of left arterial receptors. PMID- 4156369 TI - Psychological predictors of sudden death in myocardial infarction. PMID- 4156370 TI - Comparative resistance to insecticides in populations of three sympatric species of mosquitoes in the Coachella Valley of California. PMID- 4156371 TI - Experimental rearing of Chagasia bathana (Dyar) using induced mating, and description of the egg stage (Diptera: Cullicidae). PMID- 4156372 TI - [Effective use of azathioprine in a case of polyarteritis nodosa with recurrent intestinal perforation: a distinction between polyarteritis nodosa and allergic granulomatous angiitis]. PMID- 4156373 TI - Some aspects on the transmission of hepatitis B antigen; model experiments by mosquitoes with murine hepatitis virus. PMID- 4156374 TI - Studies on monoamine oxidase (report XXIV). Effect of harmine on monoamine oxidase. PMID- 4156375 TI - A ganglion blocking action of toxic substances, IS-toxin and surugatoxin, from the Japanese ivory shell, Babylonia japonica. PMID- 4156376 TI - Pharmacological features of peripheral vascular beds of beagles. PMID- 4156377 TI - Inhibition of adrenaline-induced fibrinolysis by alpha-adrenergic blocking agents in the rat. PMID- 4156378 TI - A comparative study on the mechanism of action of morphine on gastric acid secretion in dogs. PMID- 4156379 TI - Studies on monoamine oxidase. (Report XXV). Effects of alcohols on beef liver mitochondrial monoamine oxidase. PMID- 4156380 TI - [General Assembly of Portuguese Nursing Association]. PMID- 4156381 TI - [True problems of nursing, a reply to Mr. Nagakura's comments on the general meeting of the Japanese Nursing Association]. PMID- 4156382 TI - [Use of benzohexonium in the treatment of post-vagotomy complications]. PMID- 4156383 TI - The role of transcortin in glucocorticoid mediated enzyme induction: tyrosine aminotransferase induction in hepatoma tissue culture cells. PMID- 4156385 TI - [Can revaccination against smallpox damage the hearing? (AUTHOR'S TRANSL)]. PMID- 4156384 TI - [Observations about local fibrinolysis in clinical-surgery and after skin transplantation in rats (author's transl)]. PMID- 4156386 TI - [Toxicological problems of space flight]. PMID- 4156387 TI - [Studies on the effect of various substances on platelet function with several methods]. PMID- 4156388 TI - [Iatrogenic cataracts]. PMID- 4156389 TI - [Effectiveness of the use of repellents in the tundra of Krasnoiarsk region ]. PMID- 4156390 TI - [Species composition and daily activities of mosquitoes and horseflies in the lower part of the Volga delta]. PMID- 4156391 TI - [Infantile asthma. Current aspects of drug and immunological therapy]. PMID- 4156392 TI - [Pathogenesis of cerebral vasospasm]. PMID- 4156393 TI - Mammillary body fluorescence changes following septal or hippocampal lesions in the rat. PMID- 4156394 TI - An analysis of the gross behavioural changes induced by tetraethylammonium and a comparison with other substances affecting the autonomic and central nervous system after inraventricular inejctions to conscious cats. PMID- 4156395 TI - Clinical trials of topical fluorides. PMID- 4156396 TI - [Swarming of blood-sucking mosquitos in regions of northern Siberia and the Far East]. PMID- 4156398 TI - [Editorial: Physicians--spectators or leaders?]. PMID- 4156397 TI - The asexual and sexual circadian rhythms of Plasmodium vinckei chabaudi, of P. berghei and of P. gallinaceum. PMID- 4156399 TI - [Tooth colored filling materials]. PMID- 4156400 TI - Hypertension. PMID- 4156401 TI - Vasodilators.. PMID- 4156402 TI - Thyroid diseases. PMID- 4156403 TI - Epilepsy. PMID- 4156404 TI - Depressive disorders. PMID- 4156405 TI - Schistosoma mansoni. Sir Patrick Manson, 1844-1922. PMID- 4156406 TI - [Sensitivity of isolated intestine to drugs acting on adrenergic system in rabbits of different ages (author's transl)]. PMID- 4156407 TI - Proceedings: Dental plaque formation in relation to type of carbohydrate. PMID- 4156408 TI - Bioluminescence. PMID- 4156409 TI - Ion specificity of the aequorin luminescent reaction. PMID- 4156410 TI - Sedative effects on physiological and psychological measures in anxious patients. PMID- 4156411 TI - Clinical comparison of anxiolytic drug therapy. PMID- 4156412 TI - Clinical and biochemical comparison of clorazepate and diazepam. PMID- 4156413 TI - Relationship between mood and digit-symbol performance in hospitalized patients with functional psychiatric disorders. PMID- 4156414 TI - A comment on treatment analogues for phobic anxiety states. PMID- 4156415 TI - [Shock in meningococcal sepsis. Aspects on its pathogenesis and treatment]. PMID- 4156416 TI - Metabolism of pronethalol in the rat, the guinea pig and the mouse. PMID- 4156418 TI - [On the biphasic evolution of renal vascular lesions of polyarteritis nodosa]. PMID- 4156417 TI - Ovarian hormonogenesis and its alteration in the cystic disease. II(nd note). PMID- 4156419 TI - [Data analysis on the prevalence of dental caries in Campinas City, Sao Paulo, Brazil, 10 years after the fluoridation of water supply]. PMID- 4156420 TI - [Danger of general and local anesthesia in patients treated with bets-blockading agents]. PMID- 4156421 TI - Histological and histochemical studies on effects of some storage solutions on human split thickness skin grafts. PMID- 4156422 TI - [Necrotizing arteritis in infants. Review and communication of a special case involving pulmonary arteritis following surgery for congenital heart defects]. PMID- 4156423 TI - [Ambulant and stationary determination of the renin-sodium index in the classification and treatment of essential hypertension]. PMID- 4156424 TI - Effect of levamisole on the development of Breinlia sergenti in mosquitoes. PMID- 4156425 TI - [Pathological evaluation of overlapping syndrome]. PMID- 4156426 TI - [Autopsy report of 4 cases of malignant rheumatoid arthritis]. PMID- 4156427 TI - [Autopsy report of chronic rheumatoid arthritis associated with dermatomyositis and periarteritis nodosa]. PMID- 4156428 TI - [Autopsy report of chronic rheumatoid arthritis with systemic necrotizing angiitis]. PMID- 4156429 TI - An ultrastructural study on spicule formation in the pennatulid colony Renilla reniformis. PMID- 4156430 TI - Sea wasp (Chironex fleckeri) antivenene: neutralizing potency against the venom of three other jellyfish species. PMID- 4156431 TI - The toxic effect of cucumarioside C from Cucumaria fraudatrix on early embryogenesis of the sea urchin. PMID- 4156432 TI - Sarcophine--a new toxin from the soft coral Sarcophyton glaucum (Alcyonaria). PMID- 4156433 TI - Differential blockade of ganglionic transmission by extract from venom gland of black widow spider (Latrodectus mactans). PMID- 4156434 TI - Effects of sea nettle toxin on glucose transport in hamster intestine. PMID- 4156435 TI - [Psychotropic drugs, ovarian functions and mammary activity (author's transl)]. PMID- 4156436 TI - [Thioproperazine and pregnancy of the rat (author's transl)]. PMID- 4156437 TI - [Thioproperazine and transferred eggs on the rat (author's transl)]. PMID- 4156438 TI - [Transferred eggs: normal pregnancy in rats with a grafted ovary (author's transl)]. PMID- 4156439 TI - [Anti-arrhythmic and anti-anginal properties of acebutolol]. PMID- 4156440 TI - Vitamin E, selenium, and the membrane-associated drug-metabolizing enzyme system of rat liver. PMID- 4156441 TI - [Detection of the degree of infection of mosquitos in the Far East with group A arboviruses antigenically close to the Semliki forest virus]. PMID- 4156444 TI - [Prevention and treatment of the ischemic heart disease]. PMID- 4156442 TI - [Regulation of biosynthesis and oxidation of fatty acids and glycerides at the cellular level in mammalian tissues]. PMID- 4156443 TI - [Binding of exogenous coenzymes by mitochondrial structures in normal conditions and during gravitational stress]. PMID- 4156445 TI - [Adverse effects of neurolepitcs from the biochemical viewpoint]. PMID- 4156446 TI - [Influence of metabolism-inhibiting as well as metabolism-accelerating and ionotropic drugs on myocardial survival time in the rat under anoxia conditions]. PMID- 4156447 TI - [Case contribution to Kallamann's syndrome]. PMID- 4156448 TI - [The action of Th 1165 a metabolic acidosis of the fetus during the period of expulsion. A contribution to the question of intra-uterine re-animation (author's transl)]. PMID- 4156449 TI - [Manual reduction in puerperal inversio uteri following i.v. injection of the tocolytic Th 1165 a. Case report on conservative treatment of puerperal inversion (author's transl)]. PMID- 4156450 TI - [Use of medicamentous electroanesthesia in obstetrics]. PMID- 4156451 TI - Substitution of sucrose by lycasin in candy "the roslagen study". PMID- 4156452 TI - Incidence of dental caries among a group of university students in Turku. PMID- 4156453 TI - Immunofluorescence studies of extracapillary glomerulonephritis. PMID- 4156454 TI - [Professional training for a comprenhesive mental health program in Cordoba]. PMID- 4156455 TI - Rational use of psychotropic drugs. III. Major tranquilizers. PMID- 4156456 TI - [The influence of anaesthetic agents on the catecholamine synthesis in the adrenal medulla (author's transl)]. PMID- 4156457 TI - [Toxicity of divinyl ether and other inhalation anaesthetics in mice (author's transl)]. PMID- 4156458 TI - Double-blind study of flunitrazepam (Ro 5-4200) and Mandrax. PMID- 4156459 TI - [Clinical experiences with Ro 05-4200 in anaesthesia(author's transl)]. PMID- 4156460 TI - [Detection and identification of bezo-(f)-diazepine-1,4 derivatives in urine]. PMID- 4156461 TI - [Cestodes from plankton and marine invertebrates. 8th contribution (author's transl)]. PMID- 4156462 TI - [The mosquito Culiseta alaskaensis alaskaensis (Diptera Culicidae) in Dombes (author's transl)]. PMID- 4156463 TI - [The place of Takayasu's disease among granulomatous arteritides of unknown origin]. PMID- 4156464 TI - [The effect of a protein-free diet, in both donor and host, on the graft-host reaction after lymphocyte transplantation. The influence of cortisone or late thymectomy in donors (author's transl)]. PMID- 4156465 TI - Electroretinogram and the superior cervical ganglion. PMID- 4156466 TI - Thiambutene and acepromazine as analgesic and preanaesthetic agents in horses and sheep. PMID- 4156467 TI - Decreased tyrosine transaminase activity in iron deficient rat liver. PMID- 4156468 TI - Effects of acute and chronic pentobarbitone on the gamma-aminobutyric acid system in rat brain. PMID- 4156469 TI - Alteration of norepinephrine metabolism by barbiturates. PMID- 4156470 TI - Enzymic demethylation of a carcinogenic tryptophan metabolite, 8-methoxykynurenic acid. PMID- 4156471 TI - Examination of phenothiazine-albumin interaction by ultraviolet difference spectrophotometry. PMID- 4156472 TI - [Anti-complement activity of some beta-adrenergic blocking agents. Research in vitro and in vivo]. PMID- 4156473 TI - [Clinical correlation between the endocrine system and the cardiovascular system. Beta-adrenergic block in acute myocardial infarct]. PMID- 4156474 TI - [Response of the microcirculation to noradrenaline in histamine-depleted rats]. PMID- 4156475 TI - [Halothane as a depressor of the alpha adrenergic receptors]. PMID- 4156476 TI - [Carbamyl phosphate synthase (glutamine), aspartate carbamyltransferase and glutamine synthetase in the human placenta]. PMID- 4156477 TI - [Vasodilating action of dopamine on renal and mesenteric vessels after alpha and beta adrenergic blocking]. PMID- 4156478 TI - [The effect of glaziovine on exploratory behavior of normal mice in the so-called "holey board" test]. PMID- 4156479 TI - [Effect of glaziovine on exploratory activity of aggressive mice in the so-called "holey board" test]. PMID- 4156480 TI - Interactions of beta-receptor blockade and PCO2 levles in the anaesthetized dog. PMID- 4156481 TI - A comparison of lorazepam and diazepam as oral premedicants for surgery under regional anaesthesia. PMID- 4156482 TI - [Effect of Na+ and K+ ions on the rate of electron transport in microsomes]. PMID- 4156483 TI - Fatty acid synthesis in developing brain. PMID- 4156484 TI - The cardiovascular effects of intraventricular clonidine and Bay 1470 in conscious hypertensive cats. AB - 1 Intraventricular administration of clonidine (5-30 mug) and an analogue, BAY 1470 (15-30 mug) to conscious renal hypertensive cats produced a fall in mean blood pressure lasting for approximately 3 hours. This fall in blood pressure was accompanied by a marked bradycardia.2 Pretreatment with intraventricular phentolamine (100-200 mug), piperoxan (40-200 mug) or tolazoline (75-200 mug) abolished the cardiovascular effects of intraventricular clonidine (20 mug).3 The cardiovascular effects of intraventricular clonidine (20 mug) were not modified by the pretreatment with either haloperidol (1 mg/kg i.p.) or desmethylimipramine (1 mg/kg i.p.).4 Emesis was observed 1-2 min after the administration of either clonidine (5-20 mug) or BAY 1470 (30 mug). This preceded the cardiovascular actions and was still seen after pretreatment with haloperidol, desmethylimipramine, phentolamine, piperoxan or tolazoline.5 It is concluded that the centrally mediated cardiovascular responses observed after intraventricular administration of small doses of clonidine are due to stimulation of central alpha-adrenoceptors and are independent of central catecholamine uptake mechanisms and dopamine receptors. PMID- 4156485 TI - Biological actions in vivo and in vitro of two gamma-aminobutyric acid (GABA) analogues: beta-chloro GABA and beta-phenyl GABA. AB - 1 The synthesis of two analogues of gamma-aminobutyric acid (GABA), beta-chloro GABA and beta-phenyl GABA is described.2 The activity of brain GABA aminotransferase was inhibited by beta-chloro GABA (5.7 x 10(-5)M) and beta phenyl GABA (4.6 x 10(-3)M) in a competitive manner with GABA.3 beta-Chloro GABA exhibited 50% of the inhibitory activity of GABA in blocking the discharge of the crayfish stretch receptor neurone; beta-phenyl GABA had no detectable effect.4 Injection of beta-phenyl GABA (200 mg/kg) into normal or epileptic cats (cobalt) caused the appearance of synchronized slow-wave EEG activity.5 Administration of beta-chloro GABA (200 mg/kg) to epileptic cats (cobalt) produced a temporary diminution or abolition of epileptic discharges while causing no alteration in normal EEG activity.6 beta-Chloro GABA and beta-phenyl GABA had no effect on the concentrations of catecholamines or of amino acids in mouse brain.7 The results suggest that both beta-chloro GABA and beta-phenyl GABA may pass the blood-brain barrier. PMID- 4156486 TI - Proceedings: Potentiation of picrotoxin-induced convulsions in mice by antidepressants. Specificity of the effect. PMID- 4156487 TI - Proceedings: Synaptosomal exchange of gamma-aminobutyric acid (GABA) can simulate high affinity uptake. PMID- 4156488 TI - Proceedings: On the release of accumulated (3-H)-gamma-aminobutyric acid (GABA) from isolated rat superior cervical ganglia. PMID- 4156489 TI - Proceedings: Anticonvulsive action of homotaurine and taurine. PMID- 4156490 TI - Proceedings: Brain levels of the potent analgesic etorphine in rats and their functional significance. PMID- 4156491 TI - Proceedings: Dihydropteridine reductase: enzyme characteristics, regional distribution and ontogenetic development. PMID- 4156492 TI - Proceedings: Definition of the antagonistic action of burimamide and metiamide on the positive inotropic effect of histamine in isolated heart preparations. PMID- 4156493 TI - Brain histamine alterations after hypothalamic isolation. PMID- 4156494 TI - [Role of NADH in the endogeneous metabolism of types Pseudomonas fluorescens]. PMID- 4156495 TI - Commentary. Similarities of T cell function in cell-mediated immunity and antibody production. PMID- 4156496 TI - Conversion of type III pneumococcal polysaccharide low responders to high responders by immunization with a thymus-dependent form of antigen. PMID- 4156498 TI - Interaction between thymocytes and lymph-node cells in the graft-versus-host response: evidence for a synergistic and an antagonistic activity mediated by mouse thymocytes. PMID- 4156497 TI - Transfer factor: therapy in patients with deficient cell-mediated immunity and deficient antibody-mediated immunity. PMID- 4156499 TI - Survey of the relative prevalence of potential yellow fever vectors in north-west Nigeria. AB - The yellow fever epidemic in Nigeria in 1969-70 emphasized the lack of data concerning the possible importance of Aedes aegypti and other Stegomyia mosquitos as vectors. An entomological survey was therefore undertaken in September 1973 in 6 areas in the north-west of Nigeria to determine the prevalence of Stegomyia populations in the villages. An examination of over 6 700 water pots showed that 11-53% contained A. aegypti larvae, and in some areas larvae of A. vittatus were found in up to 18% of pots. In villages in the relatively dry Sudan savanna neither leaf axils nor tree-holes were important Stegomyia larval habitats, but in the more southern Kontagora area of the wetter northern Guinea savanna, these habitats were probably important breeding sites. In the early evening the most abundant man-biting mosquito in the villages was A. aegypti. A. vittatus was also caught at bait in some villages. It was concluded that the only potential yellow fever vectors in the area were A. aegypti and A. vittatus. There were large populations of A. aegypti, closely associated with man, in all the areas surveyed, but they should not present a risk of yellow fever transmission unless the disease were to be introduced into the area by man, or unless virus reservoirs, such as monkeys, were also present. Although monkeys were common in the Kontagora area they were rare in the Sudan savanna. PMID- 4156500 TI - Biochemical and immunological studies on isolated brush border membranes of human kidney cortex and their membrane surface proteins. PMID- 4156501 TI - Excitatory and inhibitory effects of noradrenaline on the isolated guinea-pig vas deferens. PMID- 4156502 TI - Visual evoked potentials as a measure of drug effects on arousal in the rabbit. PMID- 4156503 TI - Plasma renin response to acute blockade of angiotensin II in the anaesthetized rat. PMID- 4156504 TI - Non-catechol phenylethanolamines: agonistic and antagonistic actions on beta adrenoreceptors in isolated tissues from the guinea-pig. PMID- 4156507 TI - The graft versus host reaction in man after bone marrow transplantation: pathology, pathogenesis, clinical features, and implication. PMID- 4156505 TI - Cardiovascular effects of beta-adrenoreceptor blocking agents after intracerebroventricular administration in conscious normotensive cats. PMID- 4156506 TI - Central adrenoreceptors and the control of arterial blood pressure. PMID- 4156508 TI - [Clinical use of medazepam in neuropsychiatry]. PMID- 4156509 TI - Ornade and anticholinergic toxicity: hypertension, hallucinations, and arrhythmias. PMID- 4156510 TI - Water fluoridation: a choice for the community. PMID- 4156511 TI - The pharmacology of MS 222 (ethyl-m-aminobenzoate) in Squalus acanthias. PMID- 4156512 TI - The ionic mechanism of action of GABA and L-glutamate on a crustacean striated muscle (vas deferens of the crayfish). PMID- 4156513 TI - Factors influencing the circadian periodicity of plasma corticosteroid levels. PMID- 4156514 TI - Beta blockers in psychiatric illness. PMID- 4156515 TI - [A new treatment of agoraphobia: in-vivo group immersion (flooding)]. PMID- 4156517 TI - [Feldshers' and midwives' role in the prevention of diabetes mellitus in a village]. PMID- 4156516 TI - Cyclid AMP and catabolite repression in yeasts, In Schizosaccharomyces pombe glucose lowers both intracellular adenosine 3':5'-monophosphate levels and the activity of catabolite-sensitive enzymes. PMID- 4156518 TI - [Experience in participating in a competition for "Best feldsher of a health center"]. PMID- 4156519 TI - [Traumatized teeth. A clinical and radiographic follow-up study]. PMID- 4156520 TI - Bioluminescence: Chemical Aspects. PMID- 4156521 TI - Personnel development for the Illinois emergency medical services system. PMID- 4156522 TI - Illinois emergency medical service system: status report III (July, 1974). PMID- 4156523 TI - EKG of the month. PMID- 4156524 TI - The view box. PMID- 4156525 TI - Synthesis and properties of arginine oligopeptides. PMID- 4156526 TI - Deficiency of activity of succinate dehydrogenase-coenzyme Q10 reductase in leucoytes from patiens with essential hypertension. PMID- 4156527 TI - Study on vitamin A effects upon lipid peroxidation in rat liver. PMID- 4156528 TI - The utilization of glucose in the brain slices during uraemia. PMID- 4156529 TI - Fertility after treatment of bilateral cryptorchidism. PMID- 4156530 TI - Inhibition by oxalomalate of isocitrate (NADP+) dehydrogenase. PMID- 4156531 TI - Japanese encephalitis virus surveillance in Taiwan. II. Isolations from mosquitoes and bats in Taipei area 1969-1970. PMID- 4156532 TI - Design of agents for stimulation of neostriatal dopaminergic mechanisms. PMID- 4156533 TI - Inhibition of human platelet 5-hydroxytryptamine uptake by beta-phenethylamine derivatives. PMID- 4156534 TI - Interaction of phenobarbitone and ethanol in mice studied from dose-response curves and drug concentrations in blood. PMID- 4156535 TI - Effect of butriptyline on the brain uptake mechanisms for noradrenaline and 5 hydroxytryptamine. PMID- 4156536 TI - Effect of acute and chronic treatment with practolol on cardiovascular responses in the pithed rat. PMID- 4156537 TI - An analysis of the inter-subject variation in the metabolism of pentazocine. PMID- 4156538 TI - A molecular orbital study of tissue selectivity in beta-adrenoceptor blocking agents. PMID- 4156539 TI - Improved parameter estimates in drug-protein binding studies by non-linear regression. PMID- 4156540 TI - Influence of some tricyclic antidepressive drugs on the uptake of 5 hydroxytryptamine by rat blood platelets. PMID- 4156541 TI - Increased concentration of homovanillic acid in the brains of infant rabbits after administration of haloperidol to their nursing mothers. PMID- 4156542 TI - The fate of [14-c] lactose and administered into the lungs of rats and monkeys. PMID- 4156543 TI - On the mechanism of the hyperthermia induced by amphetamine in the rat. PMID- 4156544 TI - Evidence against the involvement of false neurotransmitters in tolerance to amphetamine-induced hyperthermia in the rat. PMID- 4156545 TI - The influence of atrial temperature on the in vitro selectivity of isoprenaline for atria and of orciprenaline for trachea. PMID- 4156546 TI - Triparanol-effected accumulation of desmosterol in oestrone-induced hypocholesterolaemia. PMID- 4156547 TI - Inhibition of gastric acid secretion in the rat by orally-administered synthetic prostaglandin analogues: enantiomorphs of 15-hydroxy-15-methyl-9-oxoprostanoic acid. PMID- 4156548 TI - Antispasmodic action of quaternary compounds administered orally. PMID- 4156549 TI - A human plasma fraction with anti-inflammatory but without either analgesic or antipyretic properties. PMID- 4156550 TI - A new source of anabasine. PMID- 4156551 TI - Anomalous behavior of some hydroflumethiazide crystal samples. PMID- 4156552 TI - The antimicrobial efficiencies of contact lens solutions. PMID- 4156553 TI - Some solution properties of pentagastrin and angiotensin: aggregation of pentagastrin. PMID- 4156554 TI - Aggregation of antihistamines in aqueous solution: micellar properties of some diphenylmethane derivatives. PMID- 4156555 TI - An analogue computer simulation of drug dissolution. PMID- 4156556 TI - The actions of some anticholinesterase drugs on skeletal muscle in culture. PMID- 4156558 TI - The effects of a human plasma fraction on carrageenan-induced paw oedema in the rat. PMID- 4156557 TI - Neuromuscular and other blocking actions of a new series of mono and bisquaternary aza steroids. PMID- 4156559 TI - An ESR titration technique for the determination of accessible tyrosine and tryptophan residues in globular proteins. PMID- 4156560 TI - Gas-liquid chromatographic estimation of lignocaine, ethylglycylxylidide, glycylxylidide and 4-hydroxyxylidine in plasma and urine. PMID- 4156561 TI - A gas chromatographic determination of carbenoxolone in human serum. PMID- 4156562 TI - Evaluation of the antibacterial activity of contact lens solutions. PMID- 4156563 TI - The production of extracellular lipids by Pseudomonas Aeruginosa NCTC 2000 in stationary liquid media containing macrogols. PMID- 4156564 TI - The use of desipramine in studies of noradrenergic nerve function. PMID- 4156565 TI - Interactive effect of (plus or minus)-fenfluramine and (+)-amphetamine on feeding in rats. PMID- 4156566 TI - Effects of the dopamine-beta-hydroxylase inhibitor FLA 63 on the kinetics of elimination of amphetamine in the rat. PMID- 4156567 TI - Correlation (+)-amphetamine lethality and hepatic metabolism. PMID- 4156568 TI - Long-lasting reduction of brain 5-hydroxytryptamine concentration by 3 chloramphetamine and 4-chloroamphetamine in iprindole-treated rats. PMID- 4156569 TI - Binding of (+)- and (minus)-delta-1-tetrahydrocannabinols and (minus)-7-hydroxy delta-1-tetrahydrocannabinol to blood cells and plasma proteins in man. PMID- 4156570 TI - Inhibition of eosinophil chemotaxis by the antagonist of slow reacting substance of anaphylaxis--compound FPL 55712. PMID- 4156571 TI - Characterization of phenobarbitone samples. PMID- 4156572 TI - [A liver protein factor and drug metabolizing enzymes responsible for hydroxylation of 2-aminobenzoyl derivatives]. PMID- 4156573 TI - Retained anticaries protection from topically applied acidulated phosphate fluoride: 30- and 36-month post-treatment effects. PMID- 4156574 TI - Correlations between oral hygiene status, ginigival health and dental caries in school children. PMID- 4156575 TI - [Effect of administration of miotics on serum cholinesterase]. PMID- 4156576 TI - [Radioindication control and regulation of the peripheral blood flow during anesthesia]. PMID- 4156577 TI - [Dynamics of autoantibody formation in nonspecific ulcerative colitis]. PMID- 4156578 TI - Sensitivity analysis and validation of stimulation models. PMID- 4156579 TI - [Flurazepam--a new soposfit drug]. PMID- 4156580 TI - [Pathogenic microflora of blood sucking mosquitoes of western Siberia and the Far East]. PMID- 4156581 TI - Pharmacological studies of the rabbit and human renal pelvis. PMID- 4156582 TI - The effect of ketamine upon depolarizing and non-depolarizing neuromuscular blockade in rabbit. PMID- 4156583 TI - Evidence against a causal relationship between increase in c-AMP and induction of tyrosine hydroxylase in the rat adrenal medulla. PMID- 4156584 TI - [Mechanism of functional myocardial disorders in spinal deafferentation of the heart]. PMID- 4156585 TI - [Physiopathology of angina and long term antianginal medication. Current concepts]. PMID- 4156586 TI - Hypothermia in old age. PMID- 4156587 TI - Frostbite. PMID- 4156588 TI - Prolintane in debility and fatigue. Report of a trial among college students in Cardiff. PMID- 4156589 TI - Vitamins and drug metabolism with particular reference to vitamin C. PMID- 4156590 TI - Drugs and appetite. PMID- 4156591 TI - Effect of prednisolone and cocaine on red cell volume-increased by pneumococcal endotoxin. PMID- 4156592 TI - Further observations of the effect of furosemide on mesenteric blood flow in dogs. PMID- 4156593 TI - [Polarographic determination of lorazepam (7-chloro-1,3-dihydro-3-hydroxy-5-o chlorophenyl-2H-1,4-benzodiazepin-2-one). 16. Drug analyses using polarography or oscillopolarography]. PMID- 4156594 TI - Effect of metiamide, a histamine antagonist of H2-receptors, on acid secretion of isolated canine stomach perfused with homologous blood. PMID- 4156595 TI - Effect of chronic administration of centrally acting compounds on chloramphenicol metabolism in schizophrenic patients. PMID- 4156596 TI - Public health nursing trends abroad. PMID- 4156597 TI - Patient management seminars. PMID- 4156598 TI - "Should physical therapists become physician's assistants?". PMID- 4156599 TI - [Influence of cholestasis on enzymatic induction with phenobarbital and other enzymatic aspects: experimental studies on guinea pigs]. AB - Investigations in guinea pigs to evaluate interferences between cholestasis and enzymatic induction by phenobarbital, and influences that both experimental conditions exert on the levels of gamma-glutamyl transpeptidase in microsomes and other subcellular fractions, have shown that: 1) cholestasis inhibits inductions of cytochrome P-450 from phenobarbital; 2) gamma-glutamyl transpeptidase is not an inducible enzyme in guinea pig; 3) rises or ferum gamma-glutanyl transpeptidase produced either by cholestasis or phenobarbital administration, are not related to an increased enzymatic synthesis in the various subcellular fractions of liver cell. PMID- 4156600 TI - [Evaluation of hepatic lesions in hyperthyroid conditions by means of determination of serum ornithine-carbamyl-transferase]. AB - OCT is a high specific test of liver mythocondrial damage; it increases early in the serum, before any feature of cell necrosis can histologically demonstrated. Serum values of this enzyme have been studied as an index of liver damage in 22 patients with hyperthyroidism lasting for a period of a minimum of two months to a maximum of two years. Other serum enzymes (gamma-GT, pseudocolinesterase, transaminase) have been studied comparatively. Serum OCT behaviour in the cases reported seems to suggest that hyperthyroidism can induce moderate liver functional improvement (not reliable to hemodynamic alterations) only after long time. PMID- 4156601 TI - [Angiitis caused by hypersensitivity]. PMID- 4156602 TI - [Use of RO 5-4200 as an inductor of anesthesia]. PMID- 4156603 TI - [Peritonsillar abscess in children]. PMID- 4156604 TI - [Cryoglobulins and inflammatory rheumatism]. PMID- 4156605 TI - Practical points regarding routine determination of gamma-glutamyl transferase (gamma-GT) in serum with a kinetic method at 37 degrees C. PMID- 4156606 TI - [Treatment of essential hypertension]. PMID- 4156607 TI - [Current acquisitions in treatment of angina pertoris]. PMID- 4156608 TI - [Use of modifiers of beta sympathetic activity in treatment of arterial hypertension]. PMID- 4156609 TI - [New treatments of spasticity (pyramidal hypertonia)]. PMID- 4156610 TI - [New viewpoints on the treatment of cryptorchism]. PMID- 4156611 TI - [Management of heart and circulation. 1. Circulatory agents]. PMID- 4156612 TI - [Management of heart and circulation. 2. Cardiac agents]. PMID- 4156613 TI - Stinging coral (Millepora tenera) toxin: a comparison of crude extracts with isolated nematocyst extracts. PMID- 4156614 TI - Toxic and immunological properties of stinging coral toxin. PMID- 4156615 TI - Endemic fluorosis in Ceylon. PMID- 4156616 TI - Isolation of arboviruses in Kenya, 1966-1971. PMID- 4156617 TI - A post-vaccinal inclusion body encephalitis in dogs. PMID- 4156618 TI - [Work organization of the medical post in a military air transport airfield]. PMID- 4156619 TI - Cinchophen duodenal ulcers in the mouse. PMID- 4156620 TI - [The local and bronchial tolerance of some aerosols of antihistaminics (author's transl)]. PMID- 4156621 TI - [Chemodifferentiation of the GABA-transaminase-SSA-dehydrogenase system of the olfactory blub, hippocampus and cerebellum during postnatal development of the albino rat]. PMID- 4156622 TI - [Proceedings: Case report on Wermer's syndrome. Polyadenomatosis of the endocrine system]. PMID- 4156623 TI - [Correlation between hypospadias and other congenital anomalies]. PMID- 4156624 TI - A study of flupenthixol decanoate and pipotiazine undecylenate in schizophrenics. PMID- 4156625 TI - Simplified symptom registration in psychiatric trials: a statistical approach. PMID- 4156626 TI - Attitudes of primary care physicians in the state of alabama toward physicianassistants: a preliminary report. PMID- 4156627 TI - [The influence of AH8165, a new non-depolarizing muscle relaxant on the haemodynamics in man (author's transl)]. PMID- 4156628 TI - [Use of RO 5-4200 as a hypnotic agent in neuroleptanalgesia. (Comparison with methohexital and diazepam)]. PMID- 4156629 TI - The enzymes of the hepatobiliary tract: a biochemical and clinical comparison. AB - The "biliary tract" enzymes (leucine aminopeptidase, gamma-glutamyltranspeptidase and 5'-nucleotidase) in serum reflect to varying degrees, obstruction, proliferation, inflammation and neoplasia involving the hepatobiliary duct system. Their use is directed towards two purposes: (1) as non-electrophoretic assays to evaluate the source of an elevated non-specific alkaline phosphatase and (2) to offer greater sensitivity and specificity for space-occuping lesions in the liver. In appropriate clinical states, any of the three enzymes offer these advantages and there is little to chose among them. Selection of the assay to use in the clinical laboratory then becomes based on non-clinical factors, i.e., technical ease, apparent substrate specifities, etc. With these additional factors and despite some shortcomings, our selection is leucine aminopeptidase. PMID- 4156630 TI - [Immunoglobulin or glutamine synthetase production by cells derived from a mouse myeloma]. PMID- 4156631 TI - Methemoglobin reductase variability as related to NAD glycohydrolase activity. PMID- 4156632 TI - The role of the Krebs cycle in the generation of intramitochondrial reducing equivalents for the 11 beta-hydroxylation of deoxycorticosterone in isolated rat adrenal cells. PMID- 4156633 TI - Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation. PMID- 4156634 TI - Differential effects of metabolites on the active and inactive forms of hepatic acetyl CoA carboxylase. PMID- 4156635 TI - The effect of quinolinic acid on the content and distribution of hepatic metabolites. PMID- 4156636 TI - Inhibition by cyanide of the respiratory chain oxidases of Escherichia coli. PMID- 4156637 TI - Protection by some beta-adrenergic blocking agents and other cardiovascular drugs against acute anoxia in isolated guinea-pig atria. PMID- 4156638 TI - Effect of predosing animals with immunosuppressive drugs on immune and non-immune induced inflammatory responses. PMID- 4156639 TI - Pharmacological studies with a tripeptide, prolyl-leucyl glycine amide. PMID- 4156640 TI - [Hemodynamic and hormonologic basis of the treatment of arterial hypertension]. AB - The efficiency and the variety of drugs used in the treatment of arterial hypertension demand that the various disorders responsible for the blood pressure increase be well individualized. The study of the haemodynamic and hormonal factors and of their interelations in the patients provides interesting informations which make it possible to classify the hypertensive subjects according to physiopathological criteria. Starting from these data, it is possible to consider a rational treatment by selecting the drugs acting specifically on the anomalies to be corrected. PMID- 4156641 TI - [Bioelectric cerebral changes in course of psychiatric treatment]. PMID- 4156642 TI - Giant intraabdominal seminoma: case report with a brief review of the literature. PMID- 4156643 TI - Control of uterine activity and prevention of premature birth. PMID- 4156644 TI - Effects of adrenoceptor-stimulating drugs on the myometrium and cardiovascular system in nonpregnant women. PMID- 4156645 TI - The mechanisms of ejaculation. PMID- 4156646 TI - [Electron transport in endoplasmic reticular membranes. Quantitative evaluation of the cytochrome b5 content in the NADPH and NADH oxidation chains]. PMID- 4156647 TI - [Inhibition of brain pyridoxal kinase activity by gamma-animobutyric acid]. PMID- 4156648 TI - [Induction and inhibition of mouse and rat liver tyrosine transaminase by vitamin b6 antagonists and inhibitors of pyridoxalic enzymes]. PMID- 4156649 TI - [Some properties of the NADP-malate dehydrogenase isoenzymes of the rat renal cortex]. PMID- 4156651 TI - Dwarfism and congenital medullary stenosis (Kenny syndrome). PMID- 4156650 TI - [Role of substances of a lipid nature in generating a membrane potential on submitochondrial particles]. PMID- 4156652 TI - [Energetic aspects of the effect of histamine and bradykinin on vascular permeability]. PMID- 4156653 TI - [Pyridine nucleotide concentrations in the muscles of rats following corticotropin and hydrocortisone administration]. PMID- 4156654 TI - [The effect of the type of premedication on the cardiovascular effects of inolin]. PMID- 4156655 TI - [Effect of Clomiphene on traumatic deciduoma in the pregnant or pseudopregnant rat]. PMID- 4156657 TI - [Prostaglandins are not responsible for anaphylactic hypotension in the rat]. PMID- 4156656 TI - [Activity of various neuroleptics after single repeated treatment in the mice submitted to the four plate test and the escape test]. PMID- 4156658 TI - [Variations as a function of animal species of insulin response to the activation of beta adrenergic receptors]. PMID- 4156659 TI - The effect of narcotic analgesics and their antagonists on conditioned avoidance in the rat. PMID- 4156660 TI - Blockade of the central hypotensive effect of clonidine by alpha-adrenoreceptor and antagonists in rats, rabbits and dogs. PMID- 4156661 TI - Connections of the basal ganglia and of the cerebellum. PMID- 4156662 TI - Fiber connections within the extrapyramidal system. PMID- 4156663 TI - Quantitative histochemistry of gamma-aminobutyric acid (gaba) in the human substania nigra and globus pallidus. PMID- 4156664 TI - Functional aspects of, and the role of transmitter in, the basal ganglia. PMID- 4156665 TI - Piperacetazine in ambulatory chronic schizophrenic patients. PMID- 4156666 TI - Effects of lorazepam on CNS structures: neurophysiological and behavioral correlations. PMID- 4156667 TI - Beta-blockade for hypertension. PMID- 4156669 TI - End products of human metabolism as affected by diet and space conditions. PMID- 4156670 TI - Metabolic controls in precancerous liver--VI. Studies in vivo and in vitro on feedback regulation of delta-aminolevulinic acid synthetase in ethionine-fed rats. PMID- 4156671 TI - Leukemic transformation of donor spleen cells following their transplantation into superlethally irradiated mice with pre-existing viral leukemia. PMID- 4156672 TI - Psychiatric sequelae to term birth and induced early and late abortion: a longitudinal study. PMID- 4156673 TI - Pathophysiological implications of the hepatitis associated antigen (HAA). PMID- 4156674 TI - Proceedings: Oxidative phosphorylation in intact chloroplasts. PMID- 4156675 TI - Proceedings: Control of acetyl-CoA carboxylase activity in isolated rat hepatocytes. PMID- 4156676 TI - Proceedings: Alpha-adrenergic stimulation of renal gluconeogenesis in isolated kidney tubules. PMID- 4156677 TI - Proceedings: Catalytic and regulatory properties of different mitochondrial acetoacetyl-CoA acetyltransferases from ox liver. PMID- 4156678 TI - Proceedings: Cyclic GMP, guanylate cyclase and growth control. PMID- 4156679 TI - Phosphines as ligands to microsomal cytochrome P-450. PMID- 4156680 TI - [Studies on the mechanism of the delta-4-3-oxosteroid-5alpha-reduction in rat liver microsomes (author's transl)]. PMID- 4156681 TI - Inhibitory and excitatory beta adrenergic receptors in the vas deferens of guinea pig. PMID- 4156682 TI - Metabolism of volatile anesthetics. PMID- 4156683 TI - Premedication. PMID- 4156684 TI - Postoperative analgesia. PMID- 4156685 TI - The sympathetic nerve ending. PMID- 4156686 TI - [Peroxidasosomes]. PMID- 4156687 TI - [Bacterial lipids]. PMID- 4156688 TI - [Pentose pathway of carbohydrate transformation in cardiac tissue (regulatory role or erythrose-4-phosphate]. PMID- 4156689 TI - The effect of particle size and shape on the flow and failure properties of procaine penicillin powders. PMID- 4156690 TI - Proceedings: The mechanics of inhibition of growth by some antibacterial agents. PMID- 4156691 TI - Proceedings: Enhancement of lincomycin activity against E. coli by alcohols. PMID- 4156692 TI - Proceedings: Methicillin-induced lysis of some methicillin-resistant strains of Staphylococcus aureus. PMID- 4156693 TI - Proceedings: Inactivation of beta-lactam antibiotics by Pseudomonas aeruginosa. PMID- 4156694 TI - Proceedings: A comparative study of the gamma-radiation responses of Bacillus megaterium spores suspended in aqueous solutions of ethanol and ethylene glycol. PMID- 4156695 TI - Proceedings: Granule consolidation during compaction. PMID- 4156696 TI - Proceedings: Disaggregation of compressed tablets. PMID- 4156697 TI - Proceedings: Evaluation of some tablet disintegrants and the effect of disintegrant type on the dissolution efficiency/compressional force relation. PMID- 4156698 TI - Proceedings: The effects of binding agents on granule strength and tablet strength. PMID- 4156699 TI - Proceedings: The use oa a gelatin hydrolysate to improve the compressibility of paracetamol and phenacetin. PMID- 4156700 TI - Proceedings: The effect of candicidin on exogenous cholesterol absorption in small laboratory animals. PMID- 4156701 TI - Proceedings: Factors in the experimental evaluation of calcium glycerophosphates in caries. PMID- 4156702 TI - Shearing and tensile tests on mixtures of pharmaceutical powders. PMID- 4156703 TI - Proceedings: Pharmacological studies on the leaves of Azadirachta indica. PMID- 4156704 TI - Proceedings: Alkaloids of the roots of Erythroxylum monogynum Roxb. PMID- 4156705 TI - Proceedings: Preliminary studies concerning the metabolism of hyoscine and hyoscyamine in the Solanaceae. PMID- 4156706 TI - Proceedings: Alkaloids from S. American species of Uncaria (Rubiaceae). PMID- 4156707 TI - Proceedings: The chemotaxonomic significance of alkaloids in the Naucleeae. PMID- 4156708 TI - Proceedings: Methylating and demethylating enzymes in Papaver somniferum latex. PMID- 4156709 TI - Proceedings: The equivalence of oxytetracycline tablets B.P. PMID- 4156710 TI - Proceedings: A new fluorimetric estimination of oxytetracycline in plasma: comparison with microbiological method. PMID- 4156711 TI - Proceedings: Modification of trypsin activity by anti-inflammatory drugs. PMID- 4156712 TI - Proceedings: The effect of hydrocortisone on tryptophan metabolism in the rat. PMID- 4156713 TI - Proceedings: An examination of the possible contribution of circulating corticosterone to the changes in brain monoamine metabolism during the oestrous cycle, pregnancy and the post-partum period in mice. PMID- 4156714 TI - Proceedings: The labilization of lecithin liposomes by steroidal anaesthetics: a correlation with anesthetic activity. PMID- 4156715 TI - Proceedings: Interactions of 4-chlorophenol and phenol with phosphatidylethanolamine monolayers in relation to antibacterial action. PMID- 4156716 TI - Proceedings: Lysozyme--preservative interactions in eye preparations. PMID- 4156717 TI - Proceedings: A novel sterility test for chloramphenicol. PMID- 4156718 TI - Proceedings: Inhibition of cholinesterase activity by two methylacridinium compounds. PMID- 4156719 TI - Proceedings: The effect of hydrotropic salts on the stability of liquid crystalline systems. PMID- 4156720 TI - Proceedings: Micellar interactions of bile salts with alkytrimethylammonimum bromides. PMID- 4156721 TI - Proceedings: Substituted ethoxy groups in anionic surfactants; effect on cmc, area per molecule and micellar counterion binding. PMID- 4156722 TI - Proceedings: pH-mobility plots for drug suspension systems and the effect of added surface active agents. PMID- 4156723 TI - Proceedings: Viscometric studies on surface agent solutions and the examination of hydrophobic interactions. PMID- 4156724 TI - Proceedings: Correlation of phase inversion temperature with stability of oil-in water emulsions stabilized by (polyoxyethylene)4 cetyl ether. PMID- 4156725 TI - Proceedings: Viscoelastic and continuous shear properties of Carbopol gels. PMID- 4156726 TI - Proceedings: The influence of alcohol chain length on the structure and rheology of emulsions stabilized by cetomacrogol/long chain alcohols. PMID- 4156727 TI - Proceedings: Transit in free films: casting solvent effects. PMID- 4156728 TI - Proceedings: The relationship between the physical and drug release properties of polyethyleneglycol bases. PMID- 4156729 TI - A kinetic study of human urinary excretion results for butobarbitone and its metabolites. PMID- 4156730 TI - Solute migration during granule drying. PMID- 4156731 TI - The influence of additives on the in vitro release of drugs from hard gelatin capsules. PMID- 4156732 TI - Application of polarography to the development of a stability-indicating assay method for a new indole derivative and its tablet formulations. PMID- 4156733 TI - The mechanical properties of some binders used in tableting. PMID- 4156734 TI - The effects of moisture content and gelatin binding agent on the mechanical and failure properties of an oxytetracycline formulation. PMID- 4156735 TI - Proceedings: Determination of the flow properties of powders by means of a flow balance. PMID- 4156736 TI - Proceedings: The effect of the specific surface area of primidone on its tableting properties. PMID- 4156737 TI - Proceedings: A preparative technique for studying the structure of compacts. PMID- 4156738 TI - Proceedings: Indentation hardness testing of tablets. PMID- 4156740 TI - A preliminary evaluation of a mercury intrusion method for assessing film continuity on coated tablets. PMID- 4156739 TI - The characterization of the mechanical strength of tablets. PMID- 4156741 TI - Proceedings: Apparent biological half-life values determined by administration of drug by methods other than rapid intravenous injection. PMID- 4156742 TI - Proceedings: Bioavailability of the quaternary ammonium compound thiazinamium methylsulphate (Multergan) after oral and intramuscular administration. PMID- 4156743 TI - Proceedings: A mucin model for the in vitro evaluation of mucolytic agents. PMID- 4156744 TI - Proceedings: Effect of mucin on the bioavailability of tetracycline from the gastro-intestinal tract: in vivo, in vitro correlations. PMID- 4156745 TI - Proceedings: the effect of food on the in vivo release of propranolol from a PVC matrix tablet in the dog. PMID- 4156746 TI - Proceedings: The renal clearnace of practolol in man. PMID- 4156747 TI - Proceedings: Elimination biokinetics of some topically-applied steroids. PMID- 4156748 TI - Proceedings: Stability of drugs in the presence of pharmaceutical colours. PMID- 4156749 TI - Proceedings: Catalytic degradation of hydrocortisone disodium phosphate solutions by copper (II) ions. PMID- 4156750 TI - Proceedings: Mechanism of degradation of 5-bromouracil in aqueous solutions of sodium bisulphite. PMID- 4156751 TI - Degradation of paracetamol by a Penicillium species. PMID- 4156752 TI - Proceedings: Kinetics of microagglomeration in liquid suspension. PMID- 4156753 TI - Proceedings: Self-association of some antihistamines in aqueous solution. PMID- 4156754 TI - Proceedings: Ortho-effects in structure-activity studies. Shielding of hydroxyl by alkyl groups. PMID- 4156755 TI - Proceedings: Hydrophobic substituent constants from thin-layer chromatography on polyamide plates. PMID- 4156756 TI - Proceedings: Intragranular solute migration in a test granulation dried by fluidization and vacuum tumbler drying. PMID- 4156757 TI - Proceedings: Scale up considerations in fluidized bed granulation: air flow rates and air pressure distribution. PMID- 4156758 TI - Proceedings: Particle size obtained on disintegration of phenylbutazone tablets and its relation to dissolution rate. PMID- 4156759 TI - Proceedings: Size analysis of sub-micron particles by centrifugal photosedimentometer. PMID- 4156760 TI - Proceedings: The use of an image analyser to determine the particle size distribution of salbutamol for use in metered dose inhalation aerosols. PMID- 4156761 TI - Proceedings: Disposition of disodium cromoglycate administered in three particle sizes. PMID- 4156762 TI - Proceedings: The effects of some prostaglandins on respiration in the rabbit. PMID- 4156763 TI - Proceedings: The effect of amantadine on the turnover of catecholamines in the rat brain. PMID- 4156764 TI - Proceedings: The effect of surfactants on the radiation sensitivity of benzocaine in aqueous solution. PMID- 4156765 TI - Proceedings: The effect of cosolvents on the sensitivity of benzocaine in aqueous solution to ionizing radiation. PMID- 4156766 TI - Proceedings: Investigations of solid dispersions of primidone in citric acid. PMID- 4156767 TI - Proceedings: Some effects of polyvinylpyrrolidone on the solubility and dissolution rate of allopurinol. PMID- 4156768 TI - Proceedings: The dissolution kinetics of sulphanthiazole form I. PMID- 4156769 TI - Proceedings: The thermodynamic properties of sulphanthiazole. PMID- 4156770 TI - Proceedings: Thermodynamic parameters for the solubilizaiton of some steroids by non-ionic surfactants. PMID- 4156771 TI - Proceedings: A method of testing the applicability of the diffusion layer dissolution method. PMID- 4156772 TI - Proceedings: Removal of hydrophobic surface coatings from a non-disintegrating hydrophilic solid in a water stream. PMID- 4156773 TI - Proceedings: The determination of partition coefficient data using the "AKUFVE" method. PMID- 4156774 TI - Proceedings: Some interactions between fenfluramine and antidepressant drugs: effects on 5-hydroxyindole concentrations in rat brain. PMID- 4156775 TI - Proceedings: Changes in the concentrations of 5-hydroxytryptamine and noradrenaline in six areas of rat brain during recovery from chronic methylamphetamine administration. PMID- 4156776 TI - Proceedings: Biogenic amines and the anti-nociceptive activity of agents with a non-opiate-structure. PMID- 4156777 TI - Proceedings: The binding of zinc to human serum proteins. PMID- 4156778 TI - Proceedings: the effect of blending on the physical properties of acid and alkaline gelatin gels. PMID- 4156779 TI - Proceedings: Mechanical properties of gelatin films. PMID- 4156780 TI - Proceedings: The determination of disulfiram in blood, and of exhaled carbon disulphide using cathode ray polarography. PMID- 4156781 TI - Proceedings: Sensitivity of R+ strains of Proteus mirabilis to sodium desoxycholate. PMID- 4156782 TI - Proceedings: R-factor mediated resistance to ultraviolet light. PMID- 4156783 TI - Proceedings: Trimethoprim resistance in Escherichia coli. PMID- 4156784 TI - Proceedings: The effect of some antibacterial agents on proton flux across the membrane of Clostridium welchii. PMID- 4156785 TI - Proceedings: The effect of chloroquine on the growth and viability of Escherichia coli. PMID- 4156787 TI - Regulation of catecholamine-synthesizing enzymes. PMID- 4156786 TI - Central catecholamine neurons, behavior and neuroleptic drugs: an analysis to understand the involvement of catecholamines in schizophrenia. PMID- 4156788 TI - The regulation of the noradrenergic neuron. PMID- 4156789 TI - Genetic differences in mechanisms involving neuroregulators. PMID- 4156790 TI - Possible role of catecholamines (CA) in the regulation of adrenal tyrosine hydroxylase (TH). PMID- 4156791 TI - Antipsychotic drugs and catecholamine synapses. PMID- 4156792 TI - Dose equivalence of the antipsychotic drugs. PMID- 4156793 TI - Dopaminergic blocking effects of antipsychotic drugs. PMID- 4156794 TI - New developments in the study of the mechanism of action of neuroleptics and amphetamine. PMID- 4156795 TI - Biochemical characterization of the dopamine receptor in the mammalian caudate nucleus. PMID- 4156796 TI - Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects. PMID- 4156797 TI - Antipsychotic drugs and catecholamine synapses. Summary of the session. PMID- 4156798 TI - The child health associate in a rural setting. PMID- 4156799 TI - Are there characteristics of the malpractice phenomenon peculiar to the black physician and patient. PMID- 4156800 TI - Assembly of lipids and proteins in Escherichia coli membranes. PMID- 4156801 TI - Glutamine synthetase in the embryonic chick neural retina: the effects of cycloheximide on the conservation of labile templates for enzyme synthesis. PMID- 4156802 TI - [Principles of antileukemic and immunosuppressive action of corticosteroids]. PMID- 4156803 TI - Monoamines, pyrogens and cations: their actions on central control of bodytemperature. PMID- 4156804 TI - Molecular geometry and adrenergic drug activity. PMID- 4156805 TI - Stimulatory effect of citrate on respiration and energy dependent transhydrogenation reaction in sonic particles. PMID- 4156806 TI - The physiological role of taurine in retina: uptake and effect on electroretinogram (ERG). PMID- 4156807 TI - Aspects on delivery of ear, nose, and throat care to Montana Indians. PMID- 4156808 TI - [Physiological and biochemical aspects of ethanol metabolism]. PMID- 4156809 TI - Effects of intraphippocampal administration of GABA on avoidance conditioning in the cat. Behavioral and EEG data. PMID- 4156810 TI - Teratogenic and other effects produced in mice by norethynodrel and its 3 hydroxymetabolites. PMID- 4156811 TI - [Action of various types of analgesics on the cutaneous flexion reflex in man. (Method allowing the determination of the neural mechanism of action of analgesics)]. PMID- 4156812 TI - ["Synthetic antihistamines, 30 years after their discovery"]. PMID- 4156813 TI - [The role of the chemical structure of steroid hormones in inhibiting peroxidative lipid oxidation in mitochondrial membranes]. PMID- 4156814 TI - [Oxidative catabolism of tyrosine in vitiligo]. PMID- 4156815 TI - [The peroxidase function of mitochondria]. PMID- 4156816 TI - [The effect of insulin deficiency and hydrocortisone on the activity of NADP- and NAD-dependent malate dehydrogenase in rat liver and renal cortex]. PMID- 4156817 TI - [Drug therapy of ischemic heart disease in ambulatory practice]. PMID- 4156818 TI - [Gastrogenic and pancreatogenic digestive insufficiency]. PMID- 4156819 TI - Turku sugar studies. I. An intermediate report on the effect of sucrose, fructose and xylitol diets on the caries incidence in man. PMID- 4156820 TI - Folic acid and vitamin B12: transport and conversion to coenzyme forms. PMID- 4156821 TI - Amplifying effect for glucocorticoid actions by a new polypeptide from enteric flora. PMID- 4156822 TI - The cyclic AMP system and drug development. PMID- 4156823 TI - The regulation of the pentose phosphate cycle in rat liver. PMID- 4156824 TI - [The zoogeographic situation of Timor]. PMID- 4156825 TI - Effect of endotoxin on metabolic regulation in mice. PMID- 4156826 TI - Slow conformational changes of a Neurospora glutamate dehydrogenase studied by protein fluorescence. AB - 1. The NADP-dependent glutamate dehydrogenase of Neurospora crassa undergoes slow reversible structural transitions, with half-times in the order of a few minutes, between active and inactive states. The inactive state of the enzyme, which predominates at pH values below 7.0, has an intrinsic tryptophan fluorescence 25% lower than that of the active state, which predominates at pH values above 7.6. The inactive state can be activated either by an increase in pH or by addition of activators such as succinate. 2. The kinetics of the slow transitions that follow activating and inactivating rapid changes in conditions have been monitored by measurements of protein fluorescence. The results show that the slow reversible conformational change detected by the change in fluorescence is the rate-limiting process for enzyme activation and inactivation. 3. In both directions this conformational change follows apparent first-order kinetics and the rate constant is independent of protein concentration. These kinetics and published measurements of molecular weight are indicative of an isomerization process. 4. In both directions the changes show a large energy of activation and a large positive entropy of activation, consistent with a considerable disturbance of conformation in the transition state. 5. Comparisons of the fluorescence emission spectra of the active and inactive states indicate that the difference in fluorescence is produced by quenching, possibly intramolecular, in the inactive conformation. Iodide ions cause similar quenching. 6. In some mutationally altered forms of the enzyme comparable but modified conformational changes can be followed by protein fluorescence. PMID- 4156827 TI - The enthalpy change for the reduction of nicotinamide--adenine dinucleotide. AB - The heat of the reaction NAD(+)+propan-2-ol=NADH+acetone+H(+) was determined to be 42.5+/-0.6kJ/mol (10.17+/-0.15kcal/mol) from equilibrium measurements at 9-42 degrees C catalysed by yeast alcohol dehydrogenase. With the aid of thermochemical data for acetone and propan-2-ol the values of DeltaH=-29.2kJ/mol (-6.99kcal/mol) and DeltaG(0)=22.1kJ/mol (5.28kcal/mol) are derived for the reduction of NAD (NAD(+)+H(2)=NADH+H(+)). These values are consistent with analogous but less accurate data for the ethanol-acetaldehyde reaction. Thermodynamic data for the reduction of NAD and NADP are summarized. PMID- 4156828 TI - Extraction, partial purification and properties of obelin, the calcium-activated luminescent protein from the hydroid Obelia geniculata. AB - 1. The Ca(2+)-activated luminescent protein obelin was extracted from the hydroid Obelia geniculata. 2. After the addition of a large excess of calcium (greater than 5mm) a peak in the rate of luminescence occurred within 100ms, followed by an exponential decay (k=2.8s(-1)). The obelin activity (light emitted) was measured by the peak height or by the total number of counts recorded on a scalar in the first 10s after addition of Ca(2+). 3. After an overnight extraction in 40mm-EDTA-200mm-Tris-HCl, pH7.0, 7.2x10(11) counts were obtained from 186g of wet hydroids. 4. The stability of the crude extracts was dependent on pH, being optimal at pH7.0. 5. Obelin could be purified threefold with a yield of 69% by selecting the protein precipitated between 60%- and 100%-saturated (NH(4))(2)SO(4). The precipitate could be stored for at least 6 months as a suspension in 40mm-EDTA+saturated (NH(4))(2)SO(4), pH7.0, frozen at -70 degrees C with a recovery of 95-100%. 6. Luminescence was also stimulated by Sr(2+). However, obelin appeared to have a lower affinity for Sr(2+) than for Ca(2+). Mg(2+) inhibited Ca(2+)-activated luminescence. 7. Obelin could be used to assay as little as 50pmol of Ca(2+) in a final volume of 1ml. 8. At pH7.0 in Ca(2+) EGTA [ethanedioxybis(ethylamine)tetra-acetate] buffers the rate of obelin luminescence was proportional to the square of the free Ca(2+) concentration in the presence and absence of 1 and 10mm-Mg(2+). Over the range 0.1-10mum-Ca(2+) less than 0.03% of the obelin was consumed/s. 9. In order to use obelin to study free ionized Ca(2+) concentrations similar to those found inside cells in the presence of 10mm-Mg(2+) a minimum of 10(8) counts were required. A total of 10(12) counts can be readily extracted from about 200g of wet hydroids. Thus a sufficient quantity of an aequorin-like calcium-activated luminescent protein should now be available to workers in the United Kingdom in order to carry out physiological experiments. PMID- 4156829 TI - The reconstitution of microsomal redox chains. A comparitive analysis of the effectiveness of membrane self-assembly and template binding of electron carriers. AB - A comparative analysis was made of the effectiveness of three methods for the reconstitution of microsomal electron-transfer chains, namely, self-assembly, incorporation of electron carriers into liposomes (non-specific template) and incorporation into ;ghosts' of microsomal vesicles (specific template). It was shown that when the ;ghosts' of the microsomal vesicles were used as a specific template extra cytochrome b(5) and NADH-specific flavoprotein were incorporated into them, but cytochrome P-450 and NADPH-specific flavoprotein were not incorporated into the membrane. As a result of the self-assembly and incorporation into liposomes all the electron carriers were present in the reconstituted membrane. Cytochrome P-450 reactivation took place and the inactive form, cytochrome P-420, was converted into the active form, cytochrome P-450. Of the four enzyme hydroxylation systems studied, i.e. NADPH- and NADH-dependent p hydroxylation of aniline, and NADPH- and NADH-dependent N-demethylation of dimethylaniline, only the NADH-dependent demethylation of dimethylaniline (60% of the initial value) and NADH-dependent p-hydroxylation of aniline (30% of the initial value) were reconstituted by self-assembly. NADPH oxidase and NADH oxidase activities were only properly reconstituted by self-assembly and incorporation into liposomes. In contrast, the NADPH-specific system of peroxidation of unsaturated fatty acids was reconstituted by specific template binding. PMID- 4156830 TI - Changes in respiratory activities during the cell-cycle of the fission yeast Schizosaccharomyces pompe 972h--growing in the presence of glycerol. AB - 1. The specific activities of cytochrome c oxidase, catalase, succinate dehydrogenase, succinate-cytochrome c oxidoreductase, NADH-cytochrome c oxidoreductase, and NADPH-cytochrome c oxidoreductase in mid-exponential-phase batch cultures of glycerol-grown Schizosaccharomyces pombe indicated that the organisms were catabolite-de-repressed. 2. In cultures growing synchronously in the presence of glycerol as sole carbon source, the respiration rate showed two abrupt increases at about 0.45 and 0.95 of the cell-cycle and remained constant in the periods between successive rises. 3. Catalase, succinate dehydrogenase, NADH-cytochrome c oxidoreductase and acid p-nitrophenyl-phosphatase all showed peak patterns of expression in synchronous cultures. 4. Cytochrome c oxidase and cytochromes a+a(3) both showed step patterns of expression with two rises per cell-cycle. 5. Cytochromes c(548), b(554) and b(560) all followed similar time courses in step patterns of expression, but these were distinct from, and more complex than, that of cytochromes a+a(3). 6. These results are compared with those previously obtained with glucose-grown cultures, and the part played by catabolite repression in the expression of respiratory activities in the cell cycle is assessed. PMID- 4156831 TI - Putrescine catabolism in mammalian brain. AB - In contrast with putrescine (1,4-diaminobutane), which is a substrate of diamine oxidase, monoacetylputrescine is oxidatively deaminated both in vitro and in vivo by monoamine oxidase. The product of this reaction is N-acetyl-gamma aminobutyrate. The existence of a degradative pathway in mammalian brain for putrescine is shown, which comprises acetylation of putrescine, oxidative deamination of monoacetylputrescine to N-acetyl-gamma-aminobutyrate, transformation of N-acetyl-gamma-aminobutyrate to gamma-aminobutyrate and degradation of gamma-aminobutyrate to CO(2) via the tricarboxylic acid cycle. PMID- 4156832 TI - Energy-linked reduction of nicotinamide--adenine dinucleotide in membranes derived from normal and various respiratory-deficient mutant strains of Escherichia coli K12. AB - 1. Assay conditions are described for the ATP-dependent, uncoupler-sensitive, energy-linked reduction of NAD(+) by succinate, dl-alpha-glycerophosphate or d lactate in membranes from aerobically grown Escherichia coli. 2. The reaction may be demonstrated in electron-transport particles (ET particles) from cells grown in glycerol, but not in depleted particles washed in low-ionic-strength buffer, or in ET particles from cells grown in glucose. 3. The latter two classes of particles have low specific activities of ATPase (adenosine triphosphatase), succinate dehydrogenase, dl-alpha-glycerophosphate dehydrogenase and d-lactate dehydrogenase relative to undepleted ET particles from cells grown in glycerol. 4. Reconstitution of energy-linked NAD(+) reduction in particles from cells grown in glucose was done by: (a) addition of the high-speed supernatant fraction from sonicates of the same cells; (b) addition of a protein fraction, precipitated by (NH(4))(2)SO(4) from this supernatant, or (c) addition of an (NH(4))(2)SO(4) precipitated fraction from the low-ionic-strength wash of particles from cells grown in glycerol. 5. The use of (NH(4))(2)SO(4)-precipitated fractions from ATPase- or succinate dehydrogenase-deficient mutants grown in glycerol in the above reconstitution indicated that failure to demonstrate the reaction in particles from cells grown in glucose was a result of inadequate activities of appropriate dehydrogenases, rather than of ATPase. 6. Energy-linked NAD(+) reduction could be demonstrated in particles from a ubiquinone-deficient mutant only after restoration of NADH oxidase activity by adding ubiquinone-1. 7. The measured rate of the energy-linked reaction in particles from a haem-deficient mutant, however, was not stimulated after the ATP- and haematin-dependent acquisition of functional cytochromes. 8. Results are interpreted as evidence of the ubiquinone-dependent, but cytochrome-independent, nature of the site I region of the respiratory chain in E. coli. PMID- 4156833 TI - Hormonal control of liver regeneration. AB - Two peaks in cyclic AMP production in rat livers 4 and 12h after partial hepatectomy (MacManus et al., 1972) were confirmed and a third peak established at 22h, which is the peak of DNA synthesis. The increases in cyclic AMP were prevented by beta-adrenergic blocking agents, propranolol and pindolol, without affecting ornithine decarboxylase induction or DNA synthesis. The alpha-blocking agents, phenoxybenzamine and phentolamine, given at the time of partial hepatectomy, delayed the rise in ornithine decarboxylase normally found 4h after operation, but did not affect DNA synthesis. If the alpha-blocking agents were given at 9-12h or 18h, the onset of DNA synthesis was delayed. Phenoxybenzamine did not affect the induction of ornithine decarboxylase in intact rat livers by glucagon or growth hormone, but did inhibit induction by dexamethasone. The induction of ornithine decarboxylase produced by dexamethasone was inhibited by 17alpha-hydroxy-progesterone; this compound also blocked the induction of ornithine decarboxylase in livers of partially hepatectomized rats. PMID- 4156835 TI - Pyruvate dehydrogenase activity in the normal and cryptorchid rat testis. PMID- 4156834 TI - The relative stability of liver cytosol enzymes incubated in vitro. AB - 1. Relative rates of enzyme inactivation were measured in liver slices, homogenates and cytosol fractions as well as in the presence of trypsin and at acid pH. The enzymes chosen are all present in the cytosol fraction of rat liver, and have widely different degradation rate constants in vivo. 2. The inactivation rates of lactate dehydrogenase, fructose bisphosphate aldolase, glucose 6 phosphate dehydrogenase, glucokinase, phosphoenolpyruvate carboxykinase (GTP), l serine dehydratase and thymidine kinase in liver preparations at neutral pH are in a similar order to the rate constants of degradation of these enzymes in the intact animal. 3. The two exceptions of this general correlation were tyrosine aminotransferase, which was stable in vitro but not in vivo, and glyceraldehyde phosphate dehydrogenase, which shows the reverse pattern. 4. These findings generally support the concept that the same factors are responsible for enzyme inactivation in vitro as occur in the intact tissue. PMID- 4156836 TI - The role of catecholamines and nerves in ovulation. PMID- 4156838 TI - Veterans Administration conference of prosthetics and sensory aids. July 20-23, 1974. Editorial: A basic theme of cooperation. PMID- 4156837 TI - The effect of ovulation on the response of the rabbit oviduct to adrenergic agonists in vitro. PMID- 4156839 TI - Veterans Administration conference of prosthetics and sensory aids. July 20-23, 1975. Preface. PMID- 4156840 TI - Lower-limb prosthetics workshop. PMID- 4156841 TI - Orthotics workshop. PMID- 4156842 TI - Upper-limb prosthetics workshop. PMID- 4156843 TI - Sensory-aids workshop. PMID- 4156844 TI - The spinal-cord-injured patient workshop. PMID- 4156845 TI - [Tumors of the undescended testis in the abdomen (apropos of 2 cases)]. PMID- 4156846 TI - New distribution and habitat records of biting midges and mangrove flies from the coasts of southern Baja California, Mexico (Diptera: Ceratopogonidae, Culicidae, Chironomidae, and Phoridae. PMID- 4156847 TI - World population year, 1974. PMID- 4156848 TI - The effect of a beta-adrenergic agent on prostaglandin stimulated labor. PMID- 4156849 TI - Studies on a cytochrome oxidase antibody. IV. An immunologic impurity. PMID- 4156851 TI - Decrease of DMF-levels 4 years after the introduction of a caries-preventive program, observations in 5819 schoolchildren of 20 communities. PMID- 4156850 TI - Inhibition by streptovaricins of Rauscher leukemia virus splenomegaly. AB - Streptovaricins (Sv), ansa macrolide antibiotics, inhibited Rauscher leukemia virus (RLV) splenomegaly by 25-50%. All streptovaricins tested were effective when administered orally either by diet ad lib or by intubation from infection to time of killing. When delivered by intubation, Sv was measurable in plasma for up to 6 h. SvC, at 300 mg/kg/day, reduced mean spleen weight of infected mice from 478 plus or minus 51 (SE) mg to 300 plus or minus 55 (SE) mg. Rifampicin, at 250 mg/kg/day, had no similar activity. Decrease in caloric intake and in body-weight gain also resulted in an inhibition of RLV splenomegaly; although Sv-treated mice gained weight, the increase was usually slightly less than controls. However, mice treated with a Sv diet for a week prior to infection, after an initial period of weight loss, gained at a rate equivalent to control group, and when killed had a marked reduction in splenomegaly. The selectivity of streptovaricins and specificity for viral events was suggested by several observations: (1) Splenomegaly and mortality, induced by L1210 or a non-infective transplantable tumor of RLV origin, was not inhibited. (2) No inhibition of normal hematopoietic spleen colonies was observed. (3) Host immune responses, including cellular and humoral immunity and interferon production and action, were not inhibited. Thus, although the effect of slightly decreased weight and intake could not be unequivocally established, the findings were most compatible with a selective inhibition of RLV splenomegaly by Sv. PMID- 4156852 TI - Reduction of caries, gingivitis and calculus after eight years of preventive measures--observations in seven communities. PMID- 4156853 TI - Psychotropic agents in the management of chronic asthmatic children. PMID- 4156854 TI - A study of the caries prevalence in first permanent molars of rural Zambian schoolchildren. PMID- 4156855 TI - Sensitivity of the Faschingbauer abbreviated MMPI to hospitalized adolescents. PMID- 4156856 TI - The effects of thyroid hormones on monoamine oxidase in the rat heart. PMID- 4156857 TI - Phenylalanine, brain phenethylamine and motor activity in the rat. PMID- 4156858 TI - Biliary excretion kinetics of phenolphthalein glucuronide after intravenous and retrograde biliary administration. PMID- 4156859 TI - Metabolic N- and alpha-C-oxidation of norephedrine by rabbit liver microsomal fractions and synthesis of the metabolic pdocuts. PMID- 4156860 TI - Disulphide cross-linking of thiolated alpha-chymotrypsin to form macromolecules. PMID- 4156861 TI - The dissolution of salicylic acid in micellar solutions of polysorbate 20. PMID- 4156862 TI - The uptake of digoxin and digitoxin by some antacids. PMID- 4156863 TI - Application of orthogonal functions to spectropolarimetric analysis of some penicillins. PMID- 4156864 TI - A new colorimetric method for the determination of methyldopa. PMID- 4156865 TI - The effect of dopamine and of apomorphine on dB-cAMP induced stimulation of synaptosomal tyrosine hydroxylase. PMID- 4156866 TI - Lack of effect of protriptyline on the 6-hydroxydopamine-induced noradrenaline depletion in the rat spinal cord. PMID- 4156867 TI - Acetylcholine activity in an identified 5-hydroxytryptamine containing neuron. PMID- 4156868 TI - Neuroleptics: relation between cataleptic and anti-turning actions, and role of the cholinergic system. PMID- 4156869 TI - The methylated derivatives of (+)-tubocurarine and its isomers. PMID- 4156870 TI - Pharmacological activity of some bis-benzylisoquinoline alkaloids. PMID- 4156871 TI - Different sensitivity to drugs eliciting homovanillic acid increase in two strains of mice. PMID- 4156872 TI - Interactions of imipramine and synthesis inhibitors on biogenic amines. PMID- 4156873 TI - Glucose absorption from the rat jejunum during acute exposure to metformin and phenformin. PMID- 4156874 TI - Potency ratio between the beta-adrenoceptor stimulants isoprenaline and terbutaline on rabbit detrusor muscle. PMID- 4156876 TI - Different types of drugs and their effects. PMID- 4156875 TI - Potentiation of oxytocin and prostaglandins-evoked responses by (+) INPEA on isolated rat uterus: its specificity and selectivity. AB - The effect of (+) IPNEA on various stimulant drugs was examined on isolated rat uterus. Addition of (+) IPNEA (1 times 10- minus 5 g/ml) to the organ bath, produced marked potentiation in the contractile responses of oxytocin and prostaglandins. Potentiation was less significant to 5-HT, vasopressin, angiotensin and bradykinin. (+) INPEA did not potentiate the responses of oxytocin on isolated rat mammary strip and the responses of prostaglandins on rat stomach (fundus) strip, guinea-pig tracheal chain and guinea-pig ileum. The significance of these findings has been discussed. PMID- 4156877 TI - [Use of injectable Tranxene during labor]. PMID- 4156878 TI - [Nephropathy caused by angiitis. Clinico-histological study of 3 cases of panarteritis nodosa and 1 case of Wegener's granulomatosis]. PMID- 4156879 TI - Jennerian vaccination: 2 unusual complications. PMID- 4156880 TI - [New data on the nature and function of the anticoagulation system]. PMID- 4156881 TI - [Effect of antispleen serum on the repopulation of hematopoietic cells]. PMID- 4156882 TI - Depression and drug addiction. PMID- 4156883 TI - The relationship of achievement of psychiatrists to their personal adjustment as residents. PMID- 4156884 TI - Neurohumors versus neurosecretion in the snail heart. PMID- 4156885 TI - [Meningoradiculitis: clinical, electromyographical and etiological data, apropos of 36 cases. Nosological limits]. PMID- 4156886 TI - [Ecological problems in the study of viruses and comparative virological research: biological associations and zoological groups in the biology of some animal viruses]. PMID- 4156887 TI - Successful treatment of severe experimental spinal cord injuries by intracisternal 3-alpha-dimethyltyrosine. PMID- 4156888 TI - Lymphatic regenaration in the vascular island pedicle flap. PMID- 4156889 TI - Activity of mullerian-inhibiting substance in postnatal testes. PMID- 4156890 TI - Effects of premature puberty on cryptorchid testes in rats. PMID- 4156891 TI - [NAD- and NADP-dependent dehydrogenase activity in the erythrocytes in experimental hypoxia]. PMID- 4156892 TI - The susceptibility to acetylcholine and dopamine in the caudate nucleus of cats with chronic nigrostriatal lesions. PMID- 4156893 TI - Elevation of brain gamma-aminobutyric acid in the mouse by L-2,4-diaminobutyric acid. PMID- 4156894 TI - [Studies on the Rh-(D)-properties of a low molecular weight erythrocyte membrane protein, using the Schultz-Dale reaction (author's transl)]. PMID- 4156895 TI - [NADH and NADPH dehydrogenase histochemistry in the tonsils in chronic tonsillitis]. PMID- 4156896 TI - Optimal incubation conditions for the first step of amidopyrine-N-demethylation by 9000 times g liver supernatant of newborn and adult rats. PMID- 4156897 TI - Antinuclear factors in relation to age, sex, mental disease and treatment with phenothiazines. PMID- 4156898 TI - A controlled trial of clothiapine and chlorpromazine in acute schizophrenic syndromes. PMID- 4156899 TI - Effects of histamine and noradrenaline on contractile force of guinea-pig ventricular strips: antagonism by burimamide and metiamide. PMID- 4156900 TI - [New beta-adrenergic receptor stimulators in the symptomatic treatment of asthma and chronic obstructive bronchial diseases]. PMID- 4156902 TI - American Nurses' Association 1973 Legislative Conference. Mayflower Hotel; June 5 6, 1973, Washington, D.C. No. L-89. PMID- 4156901 TI - [Post-traumatic osteitis]. PMID- 4156903 TI - [Antirabies vaccinations in France in 1973]. PMID- 4156904 TI - [The antibacterial and chemotherapeutic activity of the Soviet produced antibiotic rifamitsina SV]. PMID- 4156905 TI - [The neurotropic and myotropic properties of fucidin]. PMID- 4156906 TI - [The pharmacology of carbenicillin]. PMID- 4156907 TI - [Pulmonary pathology with miliary-like and noduliform radiological aspects]. PMID- 4156908 TI - [Ganglioneuroblastoma and ulcerative colitis. Chance association]. PMID- 4156909 TI - Factors affecting the prevalence of dental fluorosis in Luknow, India. PMID- 4156910 TI - The kinetic mechanism and properties of the cytoplasmic acetoacetyl-coenzyme A thiolase from rat liver. AB - 1. Cytoplasmic acetoacetyl-CoA thiolase was highly purified in good yield from rat liver extracts. 2. Mg(2+) inhibits the rate of acetoacetyl-CoA thiolysis but not the rate of synthesis of acetoacetyl-CoA. Measurement of the velocity of thiolysis at varying Mg(2+) but fixed acetoacetyl-CoA concentrations gave evidence that the keto form of acetoacetyl-CoA is the true substrate. 3. Linear reciprocal plots of velocity of acetoacetyl-CoA synthesis against acetyl-CoA concentration in the presence or absence of desulpho-CoA (a competitive inhibitor) indicate that the kinetic mechanism is of the Ping Pong (Cleland, 1963) type involving an acetyl-enzyme covalent intermediate. In the presence of CoA the reciprocal plots are non-linear, becoming second order in acetyl-CoA (the Hill plot shows a slope of 1.7), but here this does not imply co-operative phenomena. 4. In the direction of acetoacetyl-CoA thiolysis CoA is a substrate inhibitor, competing with acetoacetyl-CoA, with a K(i) of 67mum. Linear reciprocal plots of initial velocity against concentration of mixtures of acetoacetyl-CoA plus CoA confirmed the Ping Pong mechanism for acetoacetyl-CoA thiolysis. This method of investigation also enabled the determination of all the kinetic constants without complication by substrate inhibition. When saturated with substrate the rate of acetoacetyl-CoA synthesis is 0.055 times the rate of acetoacetyl-CoA thiolysis. 5. Acetoacetyl-CoA thiolase was extremely susceptible to inhibition by an excess of iodoacetamide, but this inhibition was completely abolished after preincubation of the enzyme with a molar excess of acetoacetyl CoA. This result was in keeping with the existence of an acetyl-enzyme. Acetyl CoA, in whose presence the overall reaction could proceed, gave poor protection, presumably because of the continuous turnover of acetyl-enzyme in this case. 6. The kinetic mechanism of cytoplasmic thiolase is discussed in terms of its proposed role in steroid biosynthesis. PMID- 4156911 TI - Partial amino acid sequence in the N-terminal region of an anti-pneumococcal immunoglobulin heavy chain of allotype alpha2. AB - The amino acid sequence of the N-terminal 48 residues of the heavy chain derived from a homogeneous rabbit antibody to type III pneumococci is described. This chain of allotype a(2) is compared with other rabbit heavy chains of allotypes a(1), a(2) and a(3). Within the N-terminal 25 positions, two chains which carry the same allotype a(2) possess identical amino acid sequences, but differ markedly from heavy chains of allotypes a(1) and a(3). Sequence variability is observed in residues 26-27 and 30-34, but not in residues 35-48. PMID- 4156912 TI - [Editorial: The methods of respiratory stimulation: present state and prospects (author's transl)]. PMID- 4156913 TI - [Ventilatory effects in healthy men of a new analeptic drug, S 2620 (author's transl)]. PMID- 4156914 TI - [Action of a respiratory stimulant (S 2620), orally administered, in obstructive bronchopulmonary disease (Statistical study) (author's transl)]. PMID- 4156915 TI - Comparison of cardiorespiratory effects of rimiterol and terbutaline aerosols. PMID- 4156916 TI - [Beta-adrenergic inhibitors (pharmacologic data and deductions for therapeutic application)]. PMID- 4156917 TI - [Structure and histochemistry of the periganglionic sheath of connective tissue surrounding the central nervous system of Crepidula fornicata (Phil) prosobranch gasteropod]. PMID- 4156918 TI - [Comparative study of the conformation of various compounds with antifibrillatory properties]. PMID- 4156919 TI - Monitoring in anesthesia. Monitoring depth of anesthesia. PMID- 4156921 TI - [Action of adrenergic substances on the smooth musculature of the bronchi in sensitization of animals by various types of allergens]. PMID- 4156920 TI - [Some aspects of the pathogenetic pharmacotherapy of acute, experimental myocardial ischemia]. PMID- 4156922 TI - [Determination of spasmolytic preparations by an interferometric method]. PMID- 4156923 TI - [Psychophysiological studies of students in the junior grades studying by the new program]. PMID- 4156924 TI - [2d day of round-table conference on "perfected methods of antibacillary treatment of pulmonary tuberculosis"]. PMID- 4156925 TI - [Experimental studies on anthelmintics. (23). Biochemical and pharmacological effects of 1-[2-(dodecyloxy) ethyl] pyrrolidine hydrochloride (DPE) on Ascaris suum]. PMID- 4156927 TI - [Correlation between hyperkalemia and hyperglyoemia. (III). Effects of isoproterenol]. PMID- 4156926 TI - [Pharmacological effects of 2-(4-benzyl-piperidino)-1-(4-hydroxyphenyl)-1 propanol (ifenprodil), with special reference to its effects on isolated arteries]. PMID- 4156928 TI - [Urticaria and Quincke's edema]. PMID- 4156929 TI - [Uricaria and Quincke's edema]. PMID- 4156930 TI - Adrenergic beta receptors in seminal vesicle. PMID- 4156931 TI - Neuroendocrine mediating mechanisms: from the symbolic stimulus to the physiological response. PMID- 4156932 TI - Anticholinesterase activity of some alpha-adrenergic blockers. PMID- 4156933 TI - [Corrected measurement of NAD(P)H' - fluorescence of the rat liver in vivo on the model of hemorrhagic shock]. PMID- 4156934 TI - [Metabolism of tricarboxylic acid cycle-bound amino acids in the brain]. PMID- 4156935 TI - Clinical experience with pipothiazine palmitate (19552 R.P.) in hospitalized and open ward patients with functional psychoses. PMID- 4156936 TI - Compendium of pharmacology. PMID- 4156937 TI - Abuse of psychopharmacological drugs experiences in Norway. PMID- 4156938 TI - Approach to a combined pharmacologic therapy of childhood hyperkinesis. PMID- 4156939 TI - Moral and legal issues--nursing judgments. PMID- 4156940 TI - [Possibilities of the therapy of hypertension with beta blockaders]. PMID- 4156941 TI - [Ethics of a seminar]. PMID- 4156942 TI - Insulin, andeyl cyclate, ions, and the heart. PMID- 4156943 TI - [Halogenated anesthetics effect on rat liver mitochondria]. PMID- 4156944 TI - [Our method for the production of antilymphocyte serum and the results of its experimental use]. PMID- 4156945 TI - [Effect of steroid narcosis on leukocyte bacterial phagocytosis]. PMID- 4156946 TI - [AUV-test for the measurement of alpha-amylase activity in serum and urine (author's transl)]. PMID- 4156947 TI - Sephadex gel filtration of gamma-glutamyl-transpeptidase, alkaline phosphatase and leucine aminopeptidase in the serum of patients affected by various liver diseases. PMID- 4156948 TI - A new enzymatic method for the estimation of inorganic phosphate in native sera. PMID- 4156949 TI - [Normal and pathological sugar metabolism]. PMID- 4156950 TI - Pharmacological approaches to the therapy of angina. PMID- 4156951 TI - [Single picture of kidney glomeruli devoid of glomera in a case of periarteritis nodosa]. PMID- 4156952 TI - [Modifications of gastric secretion during a course of phenyl-quinoline-carbonic acid (cinchophen) administration. Experimental research in the rat]. PMID- 4156953 TI - Ecological genetics of the wild rabbit in Australia. I. Geographical distribution and biochemical characterization of phosphogluconate dehydrogenase variants. PMID- 4156954 TI - Association of xanthine oxidase with the bovine milk-fat-globule membrane. AB - 1. The catalytic properties of xanthine oxidase in bovine milk (EC 1.2.3.2) are dependent on the state of the enzyme, i.e. whether free or bound to the fat globule membrane. Oxidase activity of the membrane-bound enzyme towards NADH is enhanced relative to that towards xanthine. This reflects a change in the relative K(m) values and enables the ratio of xanthine to NADH oxidase activities (X/N) to be used as a parameter for the relative amounts of free and membrane bound xanthine oxidase in milk fractions. 2. Chromatography of buttermilk on Sepharose 2B yielded an excluded fraction, BM(1), with xanthine oxidase activity. The remaining xanthine oxidase activity was eluted as a single broad peak. This was further resolved on Sephadex G-200 into an excluded fraction, BM(2), and free xanthine oxidase. Fractions BM(1) and BM(2) had X/N values in the range 45-65, which is characteristic of membrane-bound xanthine oxidase. Purified xanthine oxidase has a mean X/N value of 110.3. Addition of fraction BM(1), heated to remove associated enzyme activities, to purified xanthine oxidase progressively enhanced its NADH oxidase activity to a value where its X/N value was characteristic of membrane-bound xanthine oxidase. This was shown to be due to binding of free enzyme to heated fraction BM(1). The binding constant and stoicheiometry were determined. 4. Proteolytic digestion of fraction BM(1) liberated free xanthine oxidase from the fat-globule membrane with a corresponding alteration in X/N value. PMID- 4156955 TI - [Symposium of the mexican society of physiological introduction sciences. Introduction]. PMID- 4156956 TI - [Action of alpha-5-pyridoxal acetic acid on transaminases]. PMID- 4156957 TI - [Action of pyridoxyl-glutamic acid on transaminases]. PMID- 4156958 TI - [Changes in nucleoprotein metaboLISM IN THE RAT BRAIN. I. Effect of muscular exercise]. PMID- 4156959 TI - [Changes in nucleoprotein metabolism in the rat brain. II. Effect of the administration of a combination of oxalacetic acid, alpha-ketoglutaric acid and pyridoxal-5-phosphate in normal and fatigued animalsA1]. PMID- 4156960 TI - [Beta blockader-quinidine combination in atrial fibrillation of thyroid patients]. PMID- 4156962 TI - [Education of "medical assistants" in Tanzania]. PMID- 4156961 TI - The efficacy of systematic desensitization via imagery as a therapeutic technique with stutterers. PMID- 4156963 TI - Bronchodilators. Part I. PMID- 4156964 TI - [Parasite yield in filariasis vectors]. PMID- 4156965 TI - [Ultrastructure and specific biochemical activities of an established epithelium like cell culture obtained by enzymatic perfusion of adult Wistar rat liver]. PMID- 4156966 TI - [Testosterone in the peripheral blood of sheep with natural and experimental cryptorchidism, before and after suppression of adrenal function]. PMID- 4156967 TI - [The role of the adrenoreceptors in several organs in regulating carbohydrate and lipid metabolism]. PMID- 4156968 TI - [Tobramycin, a new aminoglycoside antibiotic]. PMID- 4156969 TI - [Methods and results of evaluating the activity of the heart in experimental metal poisonings]. PMID- 4156970 TI - [Most frequent post-Jenner complications and their treatment]. PMID- 4156971 TI - [Kidney manifestations in polyarteritis nodosa]. PMID- 4156972 TI - [Necrotic angiitis -- a clinico-diagnostic problem]. PMID- 4156973 TI - [Encephalitis after smallpox vaccination]. PMID- 4156974 TI - [Positive immuno-chemical reaction to LH in patients treated with phenothiazines]. PMID- 4156975 TI - [The influence of alpha receptor blockaders on insulin secretion stimulated by glucose during anesthesia and surgery]. PMID- 4156976 TI - Circadian chronotypic induction of tyrosine aminotransferase and depletion of glycogen by theophylline in the rat. PMID- 4156977 TI - [2 new cases of juvenil gangrenous vascularitis of the scrotum]. PMID- 4156978 TI - [Clinical results in 30 cases of human homologous renal transplants]. PMID- 4156979 TI - Guamecycline in bronchial infections due to Diplococcus pneumoniae. PMID- 4156980 TI - [Emergency chemotherapy in cases of extreme agitation]. PMID- 4156981 TI - [Beta-blocking agents in cardiology: How to select them? How to handle them]. PMID- 4156982 TI - [The causes of rhinorrhea in horses]. PMID- 4156983 TI - Enzyme histochemical studies of adipose tissue in porcine yellow fat disease. PMID- 4156984 TI - [The vector of Japanese encephalitis virus (author's transl)]. PMID- 4156985 TI - Goldthioglucose-induced lesions and quantitative changes of monoamines in the rat brain. PMID- 4156986 TI - Hormone implants in the climacterium. PMID- 4156987 TI - [Histochemical studies of the oxidation-reduction processes in the skin in Kaposi's angioreticulosis]. PMID- 4156988 TI - [Effect of psychotropic agents in emotional stress]. PMID- 4156989 TI - [Clinical structure of the initial stages of schizophrenia developing against a background of residual cerebral insufficiency]. PMID- 4156990 TI - Paper-chromatographic analysis of NADH2-oxidase and NH3-dependent NAD-reductase activity in choloragosome lipopigment of lumbricidae. PMID- 4156991 TI - [Incidence of noradrenaline in the cultures of isolated heart ventricle cells of newborn rats]. PMID- 4156992 TI - Misunderstanding or error? The UGDP report after four years. PMID- 4156993 TI - [Colony stimulating factor in graft-versus-host reaction and the changes in colony stimulating factor and in vitro colony forming cells after anabolic steroids treatment (author's transl)]. PMID- 4156994 TI - AMN-analgesia : preliminary results. PMID- 4156996 TI - Hemodynamic studies of flunitrazepam or RO 05-4200 injection in man. PMID- 4156995 TI - Clinical experimentation with flunitrazepam (Ro 05-4200). PMID- 4156997 TI - A comparative clinical study of flunitrazepam with thiopentone as an anesthetic agent. PMID- 4156998 TI - [Diffuse interstitial pulmonary fibrosis. General introduction]. PMID- 4156999 TI - [Action and reaction. Bio- and neurophysiological mechanisms]. PMID- 4157000 TI - [Anesthesia in patients with arterial hypertension]. PMID- 4157001 TI - [Environmental effect on metabolism of exogenous molecules in liver microsomes]. PMID- 4157002 TI - [Consequences of insecticide metabolism on cellular energy pathways]. PMID- 4157003 TI - [Poisoning by sedatives]. PMID- 4157004 TI - Laboratory investigations of neuroparalytic accidents associated with suckling mouse brain rabies vaccine. I.--Encephalitogenicity and virological studies. PMID- 4157005 TI - Clinical control charts. PMID- 4157006 TI - Pulmonary hypertension in Takayasu's arteritis. PMID- 4157007 TI - Isolation of mutations in Dictyostelium discoideum affecting alpha-mannosidase. PMID- 4157008 TI - Characterization of differentiated and dedifferentiated clones from a rat hepatoma. PMID- 4157009 TI - Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia. PMID- 4157010 TI - Selective T cell killing of human lymphocytes by ultraviolet radiation. PMID- 4157011 TI - The influence of a graft-versus-host reaction on the incidence of metastases after tumor transplantation. PMID- 4157012 TI - The effect of allogeneic spleen cells on the induction of immunologic tolerance. PMID- 4157013 TI - Editorial: Six years of the International Union of Immunological Societies. Presidential report (Brighton, 1974). PMID- 4157014 TI - Studies of the immunological capacity of germ-free mouse radiation chimeras. IV. Cell-mediated immunity. PMID- 4157016 TI - First appliance of dental injuried patients to the dentist. PMID- 4157015 TI - Alterations in hexose monophosphate shunt during lymphoblastic transformation. PMID- 4157017 TI - [The mechanism of the anti-inflammatory action of proteolytic enzyme preparation E-30]. AB - The author carried out a series of studies to discover some aspects of the mechanism of antiinflammatory action of bacterial proteolytic enzymic preparation E-30. It was established that in adrenalectomized rats the preparation inhibited to the same extent the development of carageninic edema of paws like that of the intact animals, which showed that its action was not connected with activation of hypothalamic-hypophysial-adrenal system. However, it inhibited t the activity of hyaluronidinase and diminished the permeability of the capillary walls and this could explain the strong antiexudative action, which the enzymic preparation possesses. In experiments on isolated intestines of rats and guinea pigs and on blood pressure of rats the author found that E-30 had moderate antihistaminic and antiserotonic action, which appeared to another important element in the complex mechanism, by which the preparation realized its antiinflammatory action. PMID- 4157018 TI - Inhibitory beta adrenergic receptors in the nictitating membrane of cat. PMID- 4157019 TI - Adrenoceptors in the heart of rana tigrina. PMID- 4157020 TI - Occupational health criteria for the evaluation of pesticides. Conclusions and recommendations of a workshop, Sofia, Bulgaria, April 9-11, 1974. PMID- 4157021 TI - Dental caries in school children at Shfar'am. An epidemiological study of an Arab population. PMID- 4157022 TI - Proceedings: Interaction between GABA and butyrophenones in cerebellar purkinje cells in cats. PMID- 4157023 TI - [Proceedings: Distribution of choline, GABA and adrenaline reactive neural control in the preoptic area]. PMID- 4157024 TI - [Proceedings: Exocytosis of autonomic nervous system transmitter substances]. PMID- 4157025 TI - Proceedings: GABA concentration in the layers of the superior colliculus. PMID- 4157026 TI - [Proceedings: Model for secretion of transmitter substances at multiple sites]. PMID- 4157027 TI - [Proceedings: Excitation of noradrenergic inhibitory nerves and ATP release]. PMID- 4157028 TI - [Proceedings: Isolation of possible transmission substances from the perfused synaptosome bed]. PMID- 4157029 TI - [Proceedings: Functions of neural transmitter substance of the central synaptic membranes in rats]. PMID- 4157030 TI - [Proceedings: Reactions between GABA and neural receptors]. PMID- 4157031 TI - [Proceedings: Sensitivity of transmitter substances and synaptic formation in cultured neurons]. PMID- 4157032 TI - [Proceedings: Pyridine nucleotide reduction in the liver induced by ethanol in vivo]. PMID- 4157034 TI - [Proceedings: Epithelial transmission in jellyfish--a theoretical consideration]. PMID- 4157033 TI - Proceedings: Effect of an autonomic ganglion blocking agent on plasma sodium concentrations in renal arteries and veins during sustained renal vein congestion. PMID- 4157035 TI - [Proceedings: Effects of 2-acetyl-7-(2-hydroxy-3-isopropylamino) propoxybenzofuran, propranolol and isoproterenol on respiration of myocardium homogenate and slices]. PMID- 4157036 TI - [Proceedings: Effect of rapid biliary clearance caused by paramidine in dogs]. PMID- 4157037 TI - [Immunopathology of collagen diseases]. PMID- 4157038 TI - [Blood serotonin during gammalon treatment of patients with acute cerebrovascular disorders]. PMID- 4157039 TI - [Differential therapy in coronary insufficiency]. PMID- 4157040 TI - [Post-vaccination complications and their prevention]. PMID- 4157041 TI - [Neurological complications after immunization of children against smallpox]. PMID- 4157042 TI - [Case of pneumococcal meningitis in a 3-month-old child]. PMID- 4157043 TI - [Letter: Immunoallergic hemolysis complicated by acute renal insufficiency after ingestion of glaphenine]. PMID- 4157044 TI - [Re-examination of long-term drug therapy in mental diseases with special reference to its non-reversible side effects]. PMID- 4157045 TI - Anaesthesia and intensive care in eclampsia. PMID- 4157046 TI - [Clinical testing of a new benzodiazepine, bromazepam, in a double blind test with thioridazine]. PMID- 4157047 TI - Fundus lesions in connective tissue disease. PMID- 4157048 TI - A rapid selective medium for the determination of trimethylamineoxide-reducing bacteria. PMID- 4157049 TI - [Industrial medicine research on deep-sea fishing in the German Democratic Republic--review and future prospects]. PMID- 4157050 TI - Observation on receptor specific proteins I. Haemagglutination and haemagglutination-inhibition reactions of two mannose-resistant strains of Escherichia coli. PMID- 4157051 TI - Humoral antibody response and GVH reactivity with neuraminidase treated murine lymphocytes as donor cells. PMID- 4157052 TI - [Synergism of conditioning and immunosuppressive treatment in the test model of the graft-versus-host-reaction (author's transl)]. PMID- 4157053 TI - Reduction of GvH splenomegaly in mice by antilymphocyte serum (ALS): correlation of the effect with immunosuppressive potency of ALS. PMID- 4157054 TI - Six years of the International Union of Immunological Societies. Presidential report, Brighton 1974. PMID- 4157055 TI - [Late spermatological results following unilateral orchidopexy]. PMID- 4157056 TI - [Endocrine glands following administration of receptor blockaders]. PMID- 4157057 TI - The Emperor's New Clothes: the reality of darvon-N. PMID- 4157058 TI - "I got a yen for that darvon-N": a pilot study on the use of propoxyphene napsylate in the treatment of heroin addiction. PMID- 4157059 TI - Treatment of polydrug users in San Francisco. PMID- 4157060 TI - Changing patterns of drug abuse in New York City. PMID- 4157061 TI - Quantitative correlation between pyrrolidonyl peptidase activity and coagulase of Staphylococci. PMID- 4157062 TI - [A new virus, Phnom-Penh bat virus, isolated in Cambodia from a short-nosed fruit bat, "Cynopterus brachyotis angulatus" Miller, 1898]. PMID- 4157063 TI - [Cutaneous periarteritis nodosa]. PMID- 4157064 TI - [Stability of the autolytic enzyme of the lyophilized Pneumococcus. Preliminary note]. PMID- 4157065 TI - [Increase of cerebral dopamine levels by alpha-chymotrypsin in rats pretreated with oxypertine and L-dopa]. PMID- 4157066 TI - Synthesis of tryptic peptides of hen egg lysozyme (positions 1-5 and 69-73) and related peptides. PMID- 4157067 TI - Determination of microquantity of ethylphenylephrine in plasma by radioisotope derivative method using p-toluenesulfonyl[35S] chloride. PMID- 4157068 TI - [Use of drug solutions on hydrophylic lenses]. PMID- 4157069 TI - [Central serous retinopathy and alpha-blockaders]. PMID- 4157070 TI - The quest for coupling site 1. PMID- 4157071 TI - Ferredoxins and photosynthesis. PMID- 4157072 TI - [Ornithosis and influenza with multiple titer rises in complement-fixation (author's transl)]. PMID- 4157073 TI - Certain concepts in the epidemiology of filariasis. A critical review. PMID- 4157074 TI - Effects of sympathomimetic tocolytic agents on the fetus. PMID- 4157075 TI - Tocolytic therapy in obstetrics. PMID- 4157076 TI - First results and experiences with our prematurity and dysmaturity prevention program (PDP-program). PMID- 4157077 TI - Sixth annual symposium on the medical aspects of sports. PMID- 4157078 TI - Pharmacological blockade. PMID- 4157079 TI - Cardiovascular events in anxiety in trained dogs: pharmacological aspects. PMID- 4157080 TI - Sympathetic control of coronary and systemic hemodynamics in emotional stress in the conscious dog. PMID- 4157081 TI - Effect of beta-receptor blockade upon myocardial hemodynamics and nutritional circulation in the heart. PMID- 4157082 TI - Mechanochemical coupling at the actomyosin cross-bridges and the adrenergic inotropic receptor. PMID- 4157083 TI - [Hypertensive encephalopathy]. PMID- 4157084 TI - [Acute pulmonary edema as a severe complication of myocardial infarct]. PMID- 4157085 TI - [Emergency measures the diagnosis and therapy of disseminated intravascular coagulation]. PMID- 4157086 TI - [Spontaneous pneumothorax]. PMID- 4157087 TI - [Residual pyelonephritis after acute renal failure due to toxico-septic shock]. PMID- 4157088 TI - [Disorders of potassium metabolism in diabetic acidoketosis]. PMID- 4157089 TI - [Current concepts concerning the role of dietetics in therapy]. PMID- 4157090 TI - [Glycoregulation disorders and diabetes mellitus in groups of elderly patients]. PMID- 4157091 TI - [Results obtained in 10 years of outpatient care of a large number of obese patients]. PMID- 4157092 TI - [Clinical aspects and treatment of diabetic autonomic neuropathies]. PMID- 4157093 TI - [Demonstration of early coronary involvement in a group of diabetics without manifest cardiovascular disease using the P wave changes in standard electrocardiograms]. PMID- 4157094 TI - [The role of glucagon in the etiopathogenesis and physiopathology of diabetes mellitus and obesity]. PMID- 4157095 TI - [Laboratory study of dyslipidemias and dyslipoproteinemias]. PMID- 4157096 TI - [Evaluation of methods of determination of serum cholesterol]. PMID- 4157097 TI - [Diazoxide]. PMID- 4157098 TI - [Current status of the surgical treatment of angina pectoris]. PMID- 4157099 TI - [Relations between the beta-adrenergic theory, synthetic bronchodilator therapy and specific hyposensitization]. PMID- 4157100 TI - [Paroxysmal atrial flutter]. PMID- 4157101 TI - [Emergency measures in digestive hemorrhage]. PMID- 4157102 TI - [Treatment of the Adams-Stokes syndrome]. PMID- 4157104 TI - [Comparative study of methods of determination of serum creatinine]. PMID- 4157103 TI - [Research on plasma renin activity in cirrhotic patients]. PMID- 4157105 TI - [Our experience with Bay-b 5097 (clotrimazole). A new antimycotic chemotherapeutic agent]. PMID- 4157107 TI - [Occupational fatique and automation]. PMID- 4157106 TI - [Biochemical and physiopathol mechanisms in epilepsy]. PMID- 4157108 TI - [Effect of elenium and related benzodiazepine derivatives on certain functions of the nervous system]. PMID- 4157109 TI - [Effect of dimecoline on certain clinico-biochemical indicators in patients with hypertensive disease]. PMID- 4157110 TI - Further data to anaphylaxis in the cat. PMID- 4157111 TI - Pharmacological studies of some central effects of tempidon. PMID- 4157112 TI - [The extent of resistance on clinically important pathogens in the Federal Republic]. PMID- 4157113 TI - [The metabolism of ethanol. II. Action of ethanol on biological amines]. PMID- 4157114 TI - Synthesis of dihydrodipicolinate synthetase in Escherichia coli K12. PMID- 4157115 TI - [Zinga virus (Ar B 1976), a new arbovirus isolated in central africa (author's transl)]. PMID- 4157116 TI - Actions of vertebrate sex hormones. PMID- 4157117 TI - Cyclic nucleotides. PMID- 4157118 TI - [Chemical findings in bromine-urea derivative poisoning]. PMID- 4157119 TI - The biosynthesis of granulose by Clostridium pasteurianum. AB - 1. Mutant strains of Clostridium pasteurianum were obtained, which are unable to synthesize granulose (an intracellularly accumulated amylopectin-like alpha polyglucan). 2. These mutants lacked either (a) ADP-glucose pyrophosphorylase (EC 2.7.7.27), or (b) granulose synthase (i.e. ADP-glucose-alpha-1,4-glucan glucosyltransferase, EC 2.4.1.21). 3. Although both of these enzymes were constitutively synthesized by the wild-type organism, massive deposition of granulose in a sporulating culture coincided with a threefold increase in the specific activity of ADP-glucose pyrophosphorylase. 4. The soluble ADP-glucose pyrophosphorylase was partially purified (33-fold). Its ATP-saturation curve was not sigmoidal and its activity was not enhanced by phosphorylated intermediates of glycolysis, pyruvate, NAD(P)H or pyridoxal 5'-phosphate. ADP at relatively high concentrations acted as a competitive inhibitor (K(i)=19mm). 5. The dependence of granulose synthase on a suitable polyglucan primer was demonstrated by using enzyme obtained from a granulose-free mutant strain (lacking ADP-glucose pyrophosphorylase). 6. Partial purification of granulose synthase from wild-type strains was facilitated by its being bound to the native particles of granulose. No activator was discovered, but ADP, AMP and pyridoxal 5'-phosphate were competitive inhibitors, ADP being most effective (K(i) about 0.2mm). 7. It would appear that the synthesis of granulose in Cl. pasteurianum is not subject to the positive, fine control that is a feature of glycogen biosynthesis in most bacteria. PMID- 4157120 TI - Mobilization of granulose in Clostridium pasteurianum. Purification and properties of granulose phosphorylase. AB - 1. The granulose of Clostridium pasteurianum ATCC 6013 is degraded when the organism is incubated in a medium containing no utilizable source of carbon and energy. 2. Mobilization of the polyglucan does not occur in the presence of exogenous glucose. 3. Breakdown of granulose is effected by a constitutively synthesized alpha-1,4-polyglucan phosphorylase. 4. Partial (530-fold) purification of this granulose phosphorylase was facilitated by its being loosely bound to the native granules of its substrate polyglucan. 5. The enzyme (pH optimum 6.4) was assayed both (a) in the degradative direction, K(m) for P(i)=2.2mm, and (b) in the synthetic direction, K(m) for glucose 1 phosphate=0.05mm. No requirement for bivalent cations was evidenced. 6. Granulose phosphorylase was inhibited by various nucleotide sugars; GDP-glucose, ADP glucose (K(i)=20mum) and UDP-glucose (K(i)=60mum) were particularly potent competitive inhibitors. ATP, NADP(+) and NADPH (at 1mm) were less effective inhibitors, whereas AMP was slightly stimulatory. 7. It would appear that granulose mobilization is favoured under conditions of low adenylate energy charge, but is prevented under conditions of ;glucose excess' chiefly by ADP glucose-mediated inhibition of granulose phosphorylase. PMID- 4157121 TI - Modulation of the immune response to transplantation antigens. III. Further studies on the effects of Freund's complete adjuvant on the immune response of mice to allogeneic tumour antigen. PMID- 4157122 TI - Enhancement and depression of the antibody response in mice caused by Corynebacterium parvum. PMID- 4157123 TI - Pharmacologic and therapeutic aspects of fluoride. PMID- 4157124 TI - Spontaneous and induced generation of optical activity in racemic 1,1' binaphthyl. PMID- 4157125 TI - Sexual dysfunction resulting from drug side effects. PMID- 4157126 TI - An evaluation of sotalol, a beta-blocking agent, in patients with angina pectoris. PMID- 4157127 TI - [Editorial: Delegation of medical activities]. PMID- 4157128 TI - [Severe endemic trachoma in Tunisia: changes in ocular bacterial pathogens in children treated by the intermittent antibiotic regimen]. PMID- 4157129 TI - [Bacteriology of the trachomatous eye]. PMID- 4157130 TI - Influence of the drugs on the immuno-allergic reactivity. IV. The action of tranquillizers on passive anaphylaxis in guinea-pig. PMID- 4157131 TI - [Skull tomography. Guiding principles and atlas]. PMID- 4157132 TI - The effect of antilymphocytic antibody on the humoral immune response of different strains of mice. V. Effects on the class and subclass of antibody produced, and the antibody responses of congenitally athymic mice. PMID- 4157133 TI - Microbial Decomposition of alpha-Picoline. AB - An organism, which degrades alpha-picoline but also utilizes 2-ethylpyridine or piperidine as alternative growth substrates, has been isolated from soil and characterized as arthrobacter sp. alpha-picoline-grown cells oxidize 2 ethylpyridine and vice versa. Other pyridine derivatives tested are neither utilized as growth substrates nor oxidized by the organism. alpha-Picolinate and 2-hydroxy-6-methylpyridine are not metabolized, indicating that degradation is neither initiated by methyl oxidation nor by hydroxylation in the 6-position of pyridine ring. Succinate semi-aldehyde and pyruvate accumulate when alpha picoline oxidation by resting cell suspensions is blocked by semicarbazide. The Arthrobacter grown on alpha-picoline rapidly oxidizes succinate semi aldehyde... PMID- 4157134 TI - Effects of alpha receptor blocking agents on tissue oxygenation during extracorporeal circulation. PMID- 4157135 TI - Pathology of hypertrophic obstructive cardiomyopathy. PMID- 4157136 TI - Diagnostic consistency in catatonic schizophrenia. PMID- 4157137 TI - [Effects of the infusion of free natural L-amino acids in the mother in the treatment of chronic feto-placental insufficiency]. PMID- 4157138 TI - [Behavior of serum gamma glutamyl transpeptidase activity during acute phase of myocardial infarct]. PMID- 4157139 TI - [A case of Takayashu's syndrome. Ophthalmologic aspects]. PMID- 4157140 TI - [Fertility after orchidopexy]. PMID- 4157141 TI - [Blood circulation in the testis in experimental cryptorchism in the rat]. PMID- 4157142 TI - [Mechanisms of growth and morphogenesis of hydroid polyps as revealed by time lapse microcinematography]. AB - By means of time lapse microcinematography, parameters of growth fluctuations in hydroid polyps Obelia and Dynamena were improved, the pulse pattern of morphogenetic processes was shown, the "antiphase" phenomenon was established in the growth fluctuations of adjacent rudiments of Dynamena. In the phase of rudiment stretching, the length of ectodermal epithelial-muscular cells reduces and their orientation changes, thus leading to the displacement of the whole cellular "column" in the distal direction. In the phase of rudiment partial shortening, endodermal cells loose and lengthen, their internal ends displace in the proximal direction and their external ends slide rapidly in the distal direction with respect to hydrotheca. Changes in the form of rudments arise as a direct mechanical result of periodical contractions of cells densely packed in the epithelial layer. On the basis of these data, morphogenetic processes in hydroid polyps related to the appearance and development of folds and to the rudiment flexures are analyzed. PMID- 4157143 TI - An ultrastructural study of axonal changes following constriction of postganglionic branches of the superior cervical ganglion in the rat. PMID- 4157144 TI - Histaminergic pathway in rat brain evidenced by lesions of the medial forebrain bundle. PMID- 4157145 TI - Synergism of insecticides by herbicides: effect of environmental factors. AB - The synergism of parathion and p,p'-DDT [1,1,1-trichloro-2,2-bis-(p chlorophenyl)ethane] by atrazine was investigated as a function of soil type, age of pesticide soil residues, and the presence of soils in quiet or turbulent water. Compared to previous tests in which the pesticides were applied on glass surfaces, a significant reduction of the toxicity of the insecticides to fruit flies and of the synergistic effects of atrazine was observed with soils, particularly a silt loam. The effects of atrazine as a synergist in soil declined rapidly within 4 days. The toxicity of parathion in water and its synergism by atrazine were significantly reduced by soil sediments, depending on the type and amount of soil present. Soils were highly effective in turbulent water: in water containing the relatively high parathion concentration of 0.3 part per million, 93 percent of the mosquito larvae present died within 24 hours, yet this solution was rendered nontoxic by being mixed with 5 grams of a loam soil. With atrazine present in the latter system, however, 38 percent of the mosquito larvae died. Thus, insecticides can be more or less toxic, depending on their concentrations, the presence of synergists, and the environmenetal conditions. PMID- 4157147 TI - The mechanism of the effect of increased biliary pressure on hepatic circulation. PMID- 4157148 TI - [Myocardial consumption of free fatty acids and carbohydrates following treatment with a new beta-blockader (1-o-methoxyphenoxy-3-isopropylamino-2-propanol HC1) D 1601]. PMID- 4157149 TI - Nicotinic acid as adjuvant therapy in newly admitted schizophrenic patients. AB - A placebo-controlled, comparative clinical study was conducted to test the hypothesis that nicotinic acid as an adjuvant medication has a beneficial therapeutic effect over and above the effect which can be achieved by the administration of phenothiazine drugs alone, over a six-month period, in newly (recently) admitted schizophrenic patients.The most important single finding was that no statistically significant therapeutic difference was seen between the active treatment and the placebo groups; i.e., the addition of nicotinic acid or nicotinamide to the regular phenothiazine treatment regimen did not have any measurable therapeutic effect in this sample of patients. It was shown that patients in the placebo group received a lower total daily amount of phenothiazine drugs than those on either of the active substances. Furthermore, it was noted that the addition of the active substances did not reduce the number of days of hospitalization. PMID- 4157150 TI - Influence of adrenergic blocking agents on lysine-vasopressin induced plasma cortisol response in man. PMID- 4157151 TI - [Gamma-glutamyltranspeptidase in myocardial infarct]. PMID- 4157152 TI - Sea anemone collagen: further evidence for the existence of only one alpha-chain type. PMID- 4157154 TI - [Current concepts in diabetology]. PMID- 4157156 TI - Report on AMSUS--80th annual meeting. PMID- 4157155 TI - Facultative IgG paraproteinaemia in polyarteritis nodosa. PMID- 4157157 TI - Navy allied health science program. PMID- 4157158 TI - [Biosynthesis of catecholamines: new concepts]. PMID- 4157159 TI - [Aminoacids transport in the brain (author's transl)]. PMID- 4157160 TI - [Microiontophoretical application of GABA and L-glutamic-acid on neurons of the mammalian C.N.S (author's transl)]. PMID- 4157161 TI - [The role of some aminoacids in the mechanisms of central inhibition (author's transl)]. PMID- 4157162 TI - [Some therapeutic effects of GABA in neurology (author's transl)]. PMID- 4157163 TI - Ultrastructural changes in skeletal muscle of rats treated with emetine and dehydroemetine. PMID- 4157164 TI - The uptake of [3H]gamma-amino butyric acid and [3H]glycine by the isolated retina of the frog. PMID- 4157165 TI - Calcium antagonism and its effect on the inhibitory actions of biogenic amines on cerebral cortical neurones. PMID- 4157167 TI - Effect of hyperphenylalaninemia on amino acid metabolism and compartmentation in neonatal rat brain. PMID- 4157166 TI - The release of amino acids with proposed neurotransmitter function from the cuneate and gracile nuclei of the rat in vivo. PMID- 4157168 TI - Effect of pentobarbital on uptake and release of [3H]GABA and [14C]glutamate by brain slices. PMID- 4157169 TI - [Physiology of the hypothalamus]. PMID- 4157170 TI - Cardiovascular and cardiac fine structural effects of the nonequilibrium alpha blocking agent, EEDQ. PMID- 4157171 TI - [Interstitial cells of the testis of cryptorchid horse cultivated in vitro]. PMID- 4157172 TI - Proceedings: A study of the involvement of adrenergic receptor stimulation in the mobilization of leucocytes in human subjects. PMID- 4157173 TI - Proceedings: The effect of dehydroemetine on vascular tissue. PMID- 4157174 TI - Dextrans. PMID- 4157175 TI - [Methods of studying the pharmacology of narcotic analgesics]. PMID- 4157176 TI - [Specificity of pharmacological trials and the idea of target structures]. PMID- 4157177 TI - Enzymes of carbohydrate metabolism in human epidermal tumors. 1. Lactate, malate, and isocitrate dehydrogenases, alanine and aspartate aminotransferases. PMID- 4157179 TI - [The problem of the two hemispheres of the brain]. PMID- 4157180 TI - [EEG activity pattern, eye movements, eyeblink rate, and heart rate in visual information processing]. PMID- 4157178 TI - [Value of electroencephalographic serveillance in the framework of resuscitation in coma caused by acute drug intoxication]. AB - The authors carried out long-term clinical and E.E.G. studies on 100 cases of acute drug poisoning. They made the following conclusions: - in unexplained coma, the E.E.G. can indicate toxic aetiology and may sometimes even suggest which drug is responsible, especially for certain chemical groups (barbiturates, phenothiasines, benzodiazepines); - the E.E.G. picture contributes a valuable indication of the depth of coma; the way in which it evolves affects the prognosis; - the effectiveness of therapy may be judged by monitoring cerebral electrical activity. PMID- 4157181 TI - [Accuracy of tracking and time required in directed movements: towards the validation of the Derwort-von Weizsacker law of constant figure time]. PMID- 4157182 TI - [Slowing of decision-making and level of activation in labile and stable persons. A study of the differential activation hypothesis]. PMID- 4157183 TI - [Effects of medazepam on the learning of 2 different programs of light discrimination]. PMID- 4157184 TI - Arterial oxygen tension during apnoea in parturient women. PMID- 4157185 TI - [Influence of Ro 05-4200 on night sleep]. PMID- 4157186 TI - [Use of acetylcholine, glutamic acid, glutamine and gama-aminobutyric acid in the cerebellum]. PMID- 4157187 TI - Letter: Medical auxiliaries. PMID- 4157188 TI - The main clinical classifications of neuroleptics. PMID- 4157189 TI - Scandinavian standpoint on the Liege classification of neuroleptics. PMID- 4157190 TI - Changing approaches to nursing research in the West. PMID- 4157191 TI - Development of communicating nursing research series. PMID- 4157192 TI - [Some aspects of neuroendocrine regulation of oxytocin release]. PMID- 4157193 TI - [Role of central nervous system monoamines in regulation of anterior pituitary function]. PMID- 4157194 TI - [Recent data on hypothalamic regulation of gonadotropic functions]. PMID- 4157195 TI - [Control of TSH secretion. I. Physiological aspects]. PMID- 4157196 TI - Vitamins and their carrier proteins in fatty acid synthesis. PMID- 4157197 TI - Autonomic neuromuscular transmission. PMID- 4157198 TI - The effect of chlorhexidine on oral anaerobes in relation to mixed infection. PMID- 4157199 TI - Adult liver parenchymal cells in primary culture characteristics and cell recognition standards. PMID- 4157201 TI - A diploid rat liver cell culture. 1. Characterization and sensitivity to aflatoxin B1. PMID- 4157200 TI - Regulation of glutamine synthetase in L cells by cortisol and L-glutamine. PMID- 4157203 TI - C.D.A. conference on dental auxiliaries: viewpoints. "You are on a course of action". PMID- 4157204 TI - [Contribution to the knowledge of testicular calculi]. PMID- 4157202 TI - Primary monolayer cultures of adult rat liver parenchymal cells suitable for study of the regulation of enzyme synthesis. PMID- 4157205 TI - Connective tissue diseases. PMID- 4157206 TI - Respiratory diseases. PMID- 4157208 TI - [Behavior of gamma-glutamyl transpeptidase (gamma GT) in the serum of chronic alcoholic patients]. PMID- 4157209 TI - The pattern of dental caries in Egyptian school children. PMID- 4157210 TI - Prevalence of dental caries and periodontal disease. PMID- 4157211 TI - Report to the Canadian Dental Association Council on Health Care. PMID- 4157212 TI - [Fluoride content of drinking water and an epidemiologic study of dental caries among schoolchildren in Hurum]. PMID- 4157213 TI - Dento-maxillary injuries of children. PMID- 4157214 TI - [Caries control in Hungary by use of fluoridated domestic salt]. PMID- 4157215 TI - [The distribution of frequencies of teeth in the DMF index]. PMID- 4157216 TI - [Incidence of new caries processes in school children in Central Slovenia]. PMID- 4157217 TI - [Desensitization as a therapy of conditioning and psychological control in the phobic child in the office]. PMID- 4157218 TI - [Basis and norms of utilization of anti-inflammatory drugs in dental surgery--2d part]. PMID- 4157219 TI - [Oral health of pupils of the Espirito Santo School. Present state and perspectives for the future]. PMID- 4157220 TI - [Epidemiologic study of the index DMF in two regions in Chile]. PMID- 4157222 TI - [Precision in soldering]. PMID- 4157221 TI - [Differential diagnosis between convulsive brain damage and other kinds of early childhood brain damages]. PMID- 4157223 TI - [Surgical cements and Bacteroides melaninogenicus: clinical and microbiological studies]. PMID- 4157224 TI - [Prevalence of dental caries and tooth mortality among students 12 to 15 years old, living in the city of Guaratingueta, State of Sao Paulo, according to age, sex and socio-economic level]. PMID- 4157225 TI - [Frequency of loss of Japanese first permanent molar teeth]. PMID- 4157226 TI - [Incidence of dental caries in 2,886 recruits originating from various regions in Italy]. PMID- 4157227 TI - [Results of a study on the prevalence of caries in pupils aged 7-14 enrolled in the official schools of the city of Medellin in the year 1974]. PMID- 4157228 TI - [Glutamine synthetase and glutaminase activity in the brain and liver homogenates and subcellular fractions of rats with alloxan diabetes (3)]. AB - Glutaminsynthetase activity has been determined in microsomal and soluble fractions of brain and liver of normal and alloxan diabetic rats and glutaminase activity in homogenates and mitochondrial fractions. The results obtained indicate that in brain of diabetic animals glutaminesynthetase activity of microsomal fractions is changed very slightly while that of the soluble fraction is marked reduced. In liver tissue enzyme activity is significantly decreased in both microsomal and soluble fractions. In homogenates of brain tissue of diabetic animals glutaminase does not differ markedly from that of control animals both in the presence and absence of activators (phosphate, aspartate, bicarbonate). In homogenates of liver, in the absence of activators, glutaminase activity is greater in diabetic animals than in controls, it is not much changed in the presence of phosphate and decreases in the presence of bicarbonate and aspartate. In diabetic animals, in the presence of phosphate, glutaminase activity of brain mitochondrial fractions increases while that of liver mitochondrial fractions does not change. It is interesting to note that in the absence of activators glutaminase activity is absent in both brain and liver mitochondria while it is quite high in homogenates. PMID- 4157229 TI - [Intracellular influence of different mediators on acid ribonuclease activity in brain tissue]. AB - The effect of acetylcholine, norepinephrine, serotonin, GABA and histone preparations on nervous tissue acid ribonuclease activity has been studied. Acetylcholine and serotonin in vitro were found to reduce the leakage of this enzyme out of lysosomes, whereas norepinephrine and histones enhanced it. These agents did not change free acid ribonuclease activity. It is assumed that these neurotransmitters and histones can take part in the regulation of intracellular RNA metabolism in brain tissue by changing the amount of the free acid ribonuclease fraction through affecting lysosome membranes rather than the activity of the free enzyme. GABA changes neither enzyme leakage out of lysosomes nor its activity. PMID- 4157230 TI - [Effect of gamma-aminobutyric acid on the concentration of noradrenaline in the synaptosoma fraction of the meso-diencephalic region of rat brain]. AB - We had previously shown [1, 2, 3, 4] that intraperitoneal administrations of 5 mg/kg amounts of gamma-aminobutyric acid (GABA) lower norepinephrine (NE) level of rat brain, this effect being most pronounced in the hypothalamic region. Subsequent studies showed that GABA increased normetanephrine level in iproniazid pretreated rats (II) and decreased NE content of crude mitochondrial fractions (12). These data implied changes in NE content of nerve endings. The results of the present study indicate that the NE content of the synaptosomal fraction of the mesodiencephalic region of GABA treated rats is significantly lower than that of untreated animals. This is a further confirmation of our previous results favouring a release of NE from nerve endings following the administration of GABA. PMID- 4157231 TI - [Effect of gamma-aminobutyric acid on the rats of synthesis and turnover time of serotonin in rat brain]. PMID- 4157232 TI - [Changes in the activities of NAD- and NADP-specific isocitrate dehydrogenases in the brain and liver during the postembryonic development of animals]. AB - The activities of NAD- and NADP-specific isocitrate dehydrogenases (ICDH) were investigated in subcellular fractions of rat brain and liver. Animals of different age groups were used: newborn, 10-, 20-, 30-, 40-days old and adult rats. It was shown that NAD-ICDH activity rose sharply in adult brain mitochondria as compared with that of developing animals. The NAD-dependent pathway of isocitrate oxidation predominated in mitochondria of both developing and adult brain. The activity of NADP-ICDH decreased in brain mitochondria and cytoplasm in the course of development. Some changes in the distribution of enzyme activity between subcellular fractions were also found in adult brain. The activity of mitochondrial NADP-ICDH was higher than that of newborn animals. PMID- 4157233 TI - [Success with fluorides. The example of Karl Marx City]. PMID- 4157234 TI - [Simplified method to estimate dental needs through direct measurement (author's transl)]. PMID- 4157236 TI - The application of invertebrate tissue culture in arboviruses studies. PMID- 4157235 TI - [Study of the relation between present and missing teeth and tooth brushing, in a group of workers of the city of S. Paulo]. PMID- 4157237 TI - Studies on arboviruses. Considerations on mosquito vectors of arboviruses in Rio de Janeiro. PMID- 4157238 TI - [An epidemiologic dental survey of an adult population with special reference to periodontal status (author's transl)]. PMID- 4157239 TI - Therapeutics in dentistry. Analgesics: 1. PMID- 4157240 TI - [Statistics on permanent tooth extractions in students]. PMID- 4157241 TI - [Dental caries occurrence in children in Sarajevo and the need for fluoridation]. PMID- 4157242 TI - [Dynamics of permanent tooth loss in schoolchildren in Sarajevo]. PMID- 4157243 TI - [Oral hygiene and caries incidence in permanent teeth of schoolchildren in Sarajevo]. PMID- 4157244 TI - [Characteristics of dental diseases in children from Belgrad]. PMID- 4157245 TI - [Experience with caries reduction with fluoride tablets in Zagreb]. PMID- 4157246 TI - Defective molecular variants of glucose-6-phosphate dehydrogenase and methaemoglobin reductase. PMID- 4157248 TI - Peculiarities in dermatology. Carbromal causing nonthrombocytopenic purpura. PMID- 4157247 TI - Sphingolipidoses. PMID- 4157249 TI - [Modern pharmacotherapy in psychiatry]. PMID- 4157250 TI - [Therapy of schizophrenic diseases]. PMID- 4157251 TI - [Therapy of depressive and manic diseases]. PMID- 4157252 TI - [Treatment of psychopathologic sequelae of early childhood brain damage]. AB - The pharmacotherapy of the psychopathological consequences of damages to the brain suffered in early childhood (erethistic or torpid oligophrenia, characteropathy, episodic psychic disorders in epilepsy, tics, and schizophrenic syndromes in encephalopathy) is discussed. PMID- 4157253 TI - Treatment of behaviour disorders in children with clinical and bioelectrical episodic symptomatology. AB - Fifty five children with episodic behaviour disorders and other behaviour disorders and a paroxysmal EEG pattern were examined clinically, psychologically and electroencephalographically. A detailed environmental analysis of social factors was made in each case. The aim of the study was a comparative analysis of the symptomatology and effects of treatment in behaviour disorders of children with and without an early lesion of the central nervous system. The authors have discussed the EEG-clinical correlations, the relationship between the effects of treatment and the clinical syndrome and EEG changes during treatment in the observed groups of children. The role of psychotherapy is emphasized, especially the influence of different environmental factors at home and at school. PMID- 4157254 TI - Endocardial lesion in a case of Takayasu's arteriopathy. AB - The clinical findings and the necropsy report of a 14-year-old girl suffering from Takayasu's arteriopathy have been presented. In addition to the typical arterial changes, thickening and puckering of the aortic valve and a patch of thickening in the left atrial endocardium were shown at necropsy. The histology of this lesion was found to be identical with the arterial intimal changes. It has been postulated that Takayasu's arteriopathy may rarely extend to the valvular and mural endocardium of the heart, producing cardiac murmurs. Similar cases with cardiac murmurs reported earlier and attributed to associated rheumatic endocarditis were probably due to the same pathological process extending to the endocarditis. PMID- 4157256 TI - Influence of hemoglobin concentration in perfusate and in blood on fluorescence of pyridine nucleotides (NADH and NADPH) of rat liver. PMID- 4157255 TI - Beta-adrenergic blocking agents and anaesthesia: a review. PMID- 4157257 TI - [The surgical treatment of coronary atherosclerosis]. PMID- 4157258 TI - [Action of beta-blocking drugs in catecholamine-induced arrhythmia]. PMID- 4157259 TI - The present status of focal glomerulonephritis. PMID- 4157260 TI - Electrical burns. A clinical and experimental study with special reference to peripheral nerve injury. PMID- 4157261 TI - The validity of mitochondrial marker enzymes in rat heart. PMID- 4157262 TI - [Contribution to the study of experimental catatonia in guinea pigs. Effect of various psychoactive drugs on this phenomenon]. PMID- 4157263 TI - The effects of "personality" and isolated demographic variables on adverse postpartum reactions: an attempt at prediction. PMID- 4157264 TI - [2 cases of Noonan syndrome in boys (so-called male Turner's syndrome)]. PMID- 4157265 TI - [Mechanism of action of factor XIII]. PMID- 4157266 TI - Water economy of the canyon mouse Peromyscus crinitus stephensi. PMID- 4157267 TI - The use of autoradiographic techniques for the identification and mapping of transmitter-specific neurones in the brain. PMID- 4157268 TI - Inhibitory beta-adrenoceptors in the urinary bladder of the rat. PMID- 4157269 TI - Effects of intraventricular brain injections of neurotransmitters on colonic temperature in morphine-tolerant rats. PMID- 4157270 TI - The use of the immobility reflex (animal hypnosis) as a possible procedure for detecting sedative activity. PMID- 4157271 TI - Biochemical studies on sub-fractions of rat liver mitochondria. PMID- 4157272 TI - Functional significance of alpha-stimulation and alpha-blockade on responses to cardiac nerve stimulation in anesthetized dogs. PMID- 4157273 TI - Daily rhythms in tyrosine transaminase and other hepatic enzymes that metabolize amino acids: mechanisms and possible consequences. PMID- 4157274 TI - Central and peripheral alpha adrenergic activity of imidazoline derivatives. PMID- 4157275 TI - Effects of neurotransmitters and other pharmacological agents on 32Pi incorporation into phospholipids of the iris muscle of the rabbit. PMID- 4157276 TI - Neurochemical correlates of synaptically active amino acids. PMID- 4157277 TI - A possible mechanism for the anti-depressant activity of thyrotropin releasing hormone. PMID- 4157278 TI - Monoamine oxidase inhibition: possible mechanism for cyproheptadine-induced alterations in insulin secretion. PMID- 4157279 TI - Regulation of tryptophan and tyrosine hydroxylase. PMID- 4157280 TI - Effect of sodium dodecyl sulfate on the kinetic properties and molecular weight of rat striatal tyrosine hydroxylase. PMID- 4157281 TI - The hepatic microsomal metabolism of beta-3,4-methylenedioxyamphetamine (MDA). PMID- 4157282 TI - Pyridine nucleotides in the thyroid gland. II. Effect of nicotinamide, nicotinic acid and L-tryptophan administration. PMID- 4157283 TI - Effects of hypophysectomy on unilaterally cryptorchid rats. PMID- 4157284 TI - Thyroxine stimulation of rat liver microsomal NADH-cytochrome c reductase in vitro. PMID- 4157285 TI - Role of peripheral resistance in the control of cardiac output. PMID- 4157286 TI - Primary arteritis of the aorta and its main branches (Takayasu's arteriopathy). A clinicopathologic autopsy study of eight cases. PMID- 4157287 TI - Long-term follow-up study of periarteritis nodosa. PMID- 4157288 TI - The effects of a beta-adrenergic blocking agent, pronethalol, on digitalis induced ventricular arrhythmias. PMID- 4157289 TI - Effect of angiotensin and beta-adrenergic stimulation on venous smooth muscle. PMID- 4157290 TI - Some pharmacological actions of the beta-adrenolytic agent Ro 3-3528 (6,7 dimethyl-alpha-[(isopropylamino) methyl]-2-benzofuranmethanol Hydrochloride). PMID- 4157291 TI - [Beta-adrenolytic and electrocardiographic effects using pitressin]. PMID- 4157292 TI - Early surgical intervention for aortic insufficiency due to bacterial endocarditis. PMID- 4157293 TI - Recommendations of the Laser Safety Conference. PMID- 4157294 TI - Effect of steroids and cofactors on the activity and stability of human placental glutamate dehydrogenase. PMID- 4157295 TI - Psychosocial conferences in medical oncology. Role in a training program. PMID- 4157296 TI - Cholinergic enzyme systems in Parkinson's disease. PMID- 4157297 TI - Psychosomatic aspects of Meniere's disease. PMID- 4157298 TI - Treatment of emotional problems in adolescents. PMID- 4157299 TI - Radioautographic studies in vitro of DNA and RNA synthesis in experimentally produced cryptorchidism in the Fischer rat. PMID- 4157300 TI - Evaluation of neurohumoral substances in local regulation of blood flow. PMID- 4157301 TI - Changes of venous return and other hemodynamic parameters during bradykinin infusion. PMID- 4157302 TI - Alteration of myocardial performance during thermal stress by beta adrenergic blockade. PMID- 4157303 TI - Detection of arboviruses by sentinel hamsters during the low period of transmission. PMID- 4157304 TI - Paradoxical effect of anti-thymocyte serum on the thymus. PMID- 4157305 TI - Paradoxical effect of ALS. PMID- 4157306 TI - Comparison of ethamivan and doxapram in the management of postanesthetic respiratory depression. PMID- 4157307 TI - Early operation for the undescended testis. PMID- 4157308 TI - Hypotensive effect of phenothiazines. PMID- 4157310 TI - Inaugural address. PMID- 4157309 TI - Indian Academy of Pediatrics. The Second National Conference. PMID- 4157311 TI - The merits of an evening arthritis clinic. PMID- 4157312 TI - Bilateral symmetrical march fractures simulating juvenile rheumatoid arthritis. PMID- 4157313 TI - Pheochromocytoma and medullary carcinoma of thyroid. PMID- 4157314 TI - Stereochemical mapping of the active site of glutamine synthetase. PMID- 4157315 TI - Some relationships between drugs and ions at a ganglionic synapse. PMID- 4157316 TI - Diffuse phlegmonous gastritis. A rare complication of pneumococcal endocarditis. PMID- 4157317 TI - Drug metabolizing ability in operating theatre personnel. PMID- 4157318 TI - The mode of action of promethazine in potentiating narcotic drugs. PMID- 4157319 TI - Metabolic assessment of internal mammary artery implantation in the dog. PMID- 4157320 TI - Internal mammary artery implantation: effect on myocardial lactate utilization. PMID- 4157321 TI - Direct blood flow studies of clinical internal thoracic (mammary) arterial implants. PMID- 4157322 TI - Reactivity of the vessels of collapsed and ventilated lungs to drugs and hypoxia. PMID- 4157323 TI - Myocardial oxygen consumption in acute experimental cardiac depression. PMID- 4157324 TI - [Significance of pyridoxine and gamma-aminobutyric acid in cerebral seizures]. PMID- 4157325 TI - [Caries attack rate in permanent teeth]. PMID- 4157326 TI - [Verification of dental conditions. Tentative standardization]. PMID- 4157327 TI - [A study concerning the nature of the optokinetic after nystagmus (report II)]. PMID- 4157328 TI - Endocrine tumours of neural crest origin: neurolophomas, apudomas and the APUD concept. PMID- 4157329 TI - Action of caffeine and theophyllamine on supersensitive dopamine receptors: considerable enhancement of receptor response to treatment with DOPA and dopamine receptor agonists. PMID- 4157330 TI - XXV Nordic Congress of Pneumonology. Goteborg, 1970. Abstracts. PMID- 4157331 TI - Evaluation of aquarium antibiotic formulations. AB - The antibacterial activity of eight products marketed for the therapy and prophylaxis of diseases of ornamental fishes was tested. The products contained erythromycin, neomycin, a nitrofuran, penicillin, sulfa compounds, streptomycin, or tetracycline. When used at the concentration recommended by the manufacturer, the products failed to inhibit the growth of bacterial species known to be potential pathogens of ornamental fishes and failed to reduce significantly the bacterial numbers in water containing fish. Concentrations of the products that were bacteriostatic were markedly higher than the in-use concentration recommended by the manufacturer. The danger presented by the unrestricted availability of antibiotic compounds frequently used in the treatment of human and animal disease is discussed. PMID- 4157332 TI - Cell culture studies on the antiviral activity of ether derivatives of 5 hydroxymethyldeoxyuridine. AB - The antiviral activity of several ether derivatives of 5 hydroxymethyldeoxyuridine against the herpesvirus of infectious bovine rhinotracheitis was determined in monolayer cultures of secondary bovine fetal kidney cells. 5-Methoxy-methyldeoxyuridine (OCH(3)UdR) was found to be markedly inhibitory against this virus. Pretreatment of the cells with OCH(3)UdR, simultaneous addition of OCH(3)UdR with virus to the cells, and postinfection treatment with OCH(3)UdR were found to be effective in inhibiting virus-induced cytopathogenic effect. Against this virus, OCH(3)UdR was found to be as potent as 5-iododeoxyuridine and cytosine arabinoside. The alpha-anomer of OCH(3)UdR did not show antiviral activity. Preliminarly toxicity studies indicate that OCH(3)UdR has a very low acute toxicity. PMID- 4157333 TI - Biochemical and genetic basis of tetracycline resistance in Staphylococcus aureus. AB - Both the genetic and biochemical basis of tetracycline resistance in a number of staphylococcal strains was investigated. The strains examined could be classified into three groups: (i) those possessing a high basal level of resistance and in which resistance could be induced to higher levels (macro-inducible); (ii) those which had a high uninduced level of resistance, but which were virtually uninducible (macro-constitutive); (iii) one derivative which had a low basal level of resistance and was also uninducible (micro-constitutive). Resistance in macro-constitutive strains was plasmid mediated and typical of organisms possessing wild-type plasmids. The macro-constitutive pattern of resistance appeared to be correlated with a chromosomal location for the resistance genes, whereas the micro-constitutive pattern was correlated with loss of a region from the wild-type plasmid. Analysis of membrane proteins by sodium dodecyl sulfate polyacrylamide gel electrophoresis suggested that a number of membrane polypeptides became unstable in staphylococci possessing high-level tetracycline resistance. In particular, the absence of a polypeptide of 22,000 daltons was always associated with high-level resistance. There was no evidence that multiple gene copies are required for expression of tetracycline resistance in Staphylococcus aureus. PMID- 4157334 TI - Polyene-resistant mutants of Aspergillus fennelliae: identification of sterols. AB - Four mutants strains of Aspergillus fennelliae resistant to various polyene antibiotics have been analyzed for their sterol content. The mutant strains contained Delta(7,22,24(28))-ergostatrien-3beta-o1 and Delta(7,22)-ergostadien 3beta-o1 as the major sterols, whereas the wild types contained ergosterol, indicating that the mutants contain metabolic blocks for C(5)-C(6) dehydrogenation and C(24)-C(28) reduction in the biosynthesis of ergosterol. Revertant sectors arising from the mutant colonies contained either more Delta(7,22)-ergostadien-3beta-o1 than the parent mutant strain or showed the reappearance of ergosterol. The revertant sectors also showed lower resistance to amphotericin B and a higher rate of sporulation than the parent mutant strain. These results confirm our previous observations that the presence of ergosterol is directly related to the drug susceptibility and the normal rate of sporulation in this species. PMID- 4157335 TI - Activity of tetracycline, doxycycline, and minocycline against methicillin susceptible and -resistant staphylococci. AB - Tetracycline, doxycycline, and minocycline were evaluated for their antibacterial activity against methicillin-susceptible and -resistant isolates of Staphylococcus. At clinically achievable levels both doxycycline and minocycline were more active than tetracycline against methicillin-susceptible organisms. Tetracycline and doxycycline had no activity against methicillin-resistant staphylococci, whereas minocycline at 2 mug/ml inhibited six of 13 strains and, at 3 mug/ml, 10 of 13 strains. PMID- 4157336 TI - Binding of aminoglycosides to feces. AB - Gentamicin and several other basic antibiotics were examined for their ability to adsorb to dog feces. It was found that 44 to 90% of all antibiotics studied were adsorbed to feces depending on the ratio of antibiotic to fecal material. Attempts to extract these antibiotics by acid treatment after adsorption onto feces were only partially successful since large portions of the bound materials were not removed. PMID- 4157337 TI - Ampicillin resistance of Shigella sonnei. AB - The ampicillin resistance of clinical isolates of Shigella sonnei is due to beta lactamase production. Two kinds of resistance are found: low level, nontransmissible; and high level, tranmissible. The nontransmissible type of resistance results from a chromosomal mutation which increases the production of a beta-lactamase that hydrolyses cephalosporins relatively rapidly and gives cephalothin resistance. The transmissible type of resistance is due to an R factor mediating the synthesis of a different beta-lactamase that does not significantly hydrolyze cephalosporins or confer cephalothin resistance. One clinical isolate is shown to possess simultaneously both these mechanisms of ampicillin resistance. PMID- 4157338 TI - Inactivation of endotoxin by polymyxin B. AB - The limulus gelation assay was utilized to investigate endotoxin inactivation by a number of antibiotics in vitro. Endotoxin activity was sharply reduced by polymyxin B and sodium colistimethate. The effect of the polymyxin was not significantly inhibited by 0.001 M calcium or 90% serum. Crude endotoxins from a variety of aerobic gram-negative bacteria, including several not previously studied, could be inactivated 1 or more logs by as little as 1 mug of polymyxin B per ml, whereas Bacteroides fragilis endotoxin was poorly detoxified. A 10,000 fold range in the relative susceptibility of different endotoxins to inactivation by polymyxin B was found. The endotoxin most susceptible to polymyxin B was derived from an organism resistant to polymyxin B by disk sensitivity testing, suggesting that the bacteriocidal and endotoxin detoxifying properties of polymyxin need not be directly related. PMID- 4157339 TI - Biliary tract excretion of cefazolin, cephalothin, and cephaloridine in the presence of biliary tract disease. AB - The biliary tract excretion of three cephalosporins, cefazolin, cephaloridine, and cephalothin, was compared in patients with biliary tract disease. In the absence of obstruction, mean antibiotic levels in bile from gall bladder and common duct in patients undergoing cholecystectomy were highest for cefazolin (17 and 31 mug/ml, respectively) than either cephaloridine (7 and 9 mug/ml) or cephalothin (1 and 4 mug/ml). Biliary tract levels generally paralleled serum levels. In no patient with cystic duct obstruction were any of the cephalosporins detectable in appreciable amounts in gall bladder bile. In patients with T-tube drainage given each of the three different cephalosporins on separate days, concentrations of cefazolin in bile were many-fold higher than either cephaloridine or cephalothin. Peak levels of cefazolin in T-tube bile averaged 51 mug/ml after intravenous and 26 mug/ml after intramuscular administration, whereas mean peak levels of cephalothin and cephaloridine were only 6 and 16 mug/ml, respectively. Here, too, T-tube levels reflected serum concentrations and obstruction to biliary flow impaired excretion of each of the drugs. PMID- 4157340 TI - Cinoxacin: effectiveness against experimental pyelonephritis in rats. AB - The antimicrobial activity of cinoxacin, 1-ethyl-4(1H)-oxo-[1,3]dioxolo[4,5 g]cinnoline-3-carboxylic acid, previously reported as compound 64716, was determined and compared with other antimicrobial agents at a dosage of 12 mg/kg once daily in a descending pyelonephritis rat model with Escherichia coli and Proteus mirabilis as infecting organisms. Cinoxacin was considerably more effective than either nalidixic acid or oxolinic acid when all three were administered orally at 3 mg/kg four times daily. The presence of demonstrable serum activity with a high recovery in urine indicates cinoxacin possesses highly desirable properties of an effective oral chemotherapeutic agent for urinary tract infections. PMID- 4157341 TI - Effect of probenecid on cerebrospinal fluid concentrations of penicillin and cephalosporin derivatives. AB - Probenecid may elevate the cerebrospinal fluid (CSF) concentration of penicillin G by inhibiting the excretion of organic acids from CSF. We have studied this phenomenon with various penicillin and cephalosporin derivatives. Penicillin concentrations were determined in rabbits under steady-state conditions before and after intravenous probenecid administration. With both low-dose and high-dose probenecid, CSF penicillin levels increased two to three times as did CSF concentration as a percentage of serum level. The same probenecid effect was consistently demonstrated in animals with experimental pneumococcal meningitis. Probenecid likewise increased the CSF concentration of ampicillin, carbenicillin, nafcillin, cephacatrile, and cefazolin. Probenecid may prove useful in certain bacterial infections where high CSF antibiotic levels are necessary. PMID- 4157342 TI - Comparative activity of tobramycin, amikacin, and gentamicin alone and with carbenicillin against Pseudomonas aeruginosa. AB - The effect of gentamicin against 130 clinical isolates of Pseudomonas aeruginosa was compared with that of two investigational aminoglycoside antibiotics, tobramycin and amikacin. Minimal inhibitory concentration data indicated that, on a weight basis, tobramycin was two to four times as active as gentamicin against most isolates. However, 14 of 18 organisms highly resistant to gentamicin (>/=80 mug/ml) were also highly resistant to tobramycin. Amikacin was the least active aminoglycoside on a weight basis, but none of the isolates were highly resistant to this antibiotic. When therapeutically achievable concentrations were used, adding carbenicillin to gentamicin or to tobramycin enhanced inhibitory activity against those isolates susceptible ( 500 mug/ml) were also highly resistant to BL-P1654. When an MIC of 32 mug/ml or less and a zone of inhibition of 12 mm or more by a 10-mug disk were used as criteria indicating susceptibility to BL-P1654, the false-resistance rate by the disk test was 10.6% and the false-susceptibility rate was 4.2%. The combination of BL-P1654 and gentamicin was synergistic against 45 of 70 isolates of P. aeruginosa tested, but synergism was demonstrated against only 4 of 24 highly gentamicin-resistant (MIC > 63 mug/ml), 1 of 12 highly BL-P1654-resistant (MIC > 250 mug/ml) isolates, and none of nine isolates highly resistant to both of these antibiotics. PMID- 4157348 TI - Binding of [14C]erythromycin to Escherichia coli ribosomes. AB - Erythromycin binding to Escherichia coli ribosomes required K(+) and Mg(2+). Under optimal conditions, the dissociation constant for erythromycin binding to E. coli ribosomes was found to be 1.0 x 10(-8) M and 1.4 x 10(-8) M at 24 C and 5 C, respectively. One molecule of [(14)C]erythromycin was bound to each 70S ribosome at equilibrium. Binding of erythromycin to ribosomes was rapid and reversible. The specific rate constants for the forward and reverse reactions were 1.7 x 10(7) liters per mol per min and 0.15 per min, respectively. PMID- 4157349 TI - Effect of erythromycin analogues on binding of [14C]erythromycin to Escherichia coli ribosomes. AB - The relative ability of 44 erythromycin analogues to bind to ribosomes was determined by their effect on [(14)C]erythromycin binding to Escherichia coli ribosomes. The association and dissociation constants of each of these erythromycin derivatives were determined as well as their interaction coefficient for their binding to ribosomes. Substitutions were made on various portions of the erythromycin molecule with retention of substantial activity as measured by inhibition of [(14)C]erythromycin binding to ribosomes. Since the effect of erythromycin analogues on [(14)C]erythromycin binding to ribosomes provides a relatively sensitive assay for these compounds, erythromycin analogues with relatively little affinity for ribosomes could be detected. Compounds with association constants of 10(4) M(-1) were detectable; the association constant for erythromycin binding to ribosomes was approximately 10(8) M(-1). Thus, compounds with 0.0001 the association constant of erythromycin were detectable. This assay could be used alone or in conjunction with microbiological assays for primary screening of active analogues or other compounds which interfere with [(14)C]erythromycin binding to ribosomes. It permits an estimate of the general activity of compounds rapidly and directly. Variables such as metabolic modifications of the compounds and permeability are excluded. The present assay reflects the ability of the compounds to interact directly with their target organelle and may serve as a useful adjunct in developing new compounds. PMID- 4157350 TI - Correlation of effects of erythromycin analogues on intact bacteria and on [14C]erythromycin binding to Escherichia coli ribosomes. AB - The dissociation constants for binding to ribosomes from Escherichia coli and concentrations at which 50% inhibition of [(14)C]erythromycin binding to ribosomes occurred were determined for 45 erythromycin analogues. These values were correlated with their antibacterial activities against Bacillus subtilis. Compounds which bound to ribosomes best showed the greatest activities; those which were poorly bound to ribosomes showed little or no antibacterial activity. The ribosomal binding assays therefore reflected the general antibacterial potential of the erythromycin analogues. PMID- 4157351 TI - Transferrable resistance to tobramycin in Klebsiella pneumoniae and Enterobacter cloacae associated with enzymatic acetylation of tobramycin. AB - Among gram-negative bacilli isolated from burn wound cultures, some strains of Enterobacteriaceae were resistant to tobramycin (minimal inhibitory concentration [MIC]>/= 20 mug/ml) but susceptible to gentamicin (MIC 90% in adults. Fluorescein-isothiocyanate-conjugated human gamma globulins were suitable for direct staining of the same proportion of cells. The stained cells appeared to be in varying stages of degeneration, but cultural conditions leading to an increase in the cellular death rates failed to result in a rise in fluorescent cells. Several observations suggest that the stainable cells might be those which are seen to harbor virus particles under the electron microscope. Two cell lines derived from leukemic patients in this country also contained a small fraction of stainable cells but two others, and numerous primary human leukocyte cultures, gave consistently negative results. Attempts to relate the staining to known viral antigens have failed to implicate herpes simplex, varicella, cytomegalo, and reo viruses types 1, 2, and 3. The nature of the virus carried by the lymphoma cells as well as of the staining reactions remains to be determined. PMID- 4160231 TI - Isolation of Candida protoplasts from a case of Candida endocarditis. AB - Rosner, Richard (St. Joseph's Hospital, Paterson, N.J.). Isolation of Candida protoplasts from a case of Candida endocarditis. J. Bacteriol. 91:1320-1326. 1966.-A case of endocarditis caused by Candida tropicalis is described. Even though the patient was receiving adequate therapy, and all routine blood cultures were negative for growth, the patient continued to give clinical evidence of active, progressive endocarditis. The isolation of osmotically fragile bodies from blood cultures placed in an osmotically controlled medium is described in detail. The role of these bodies, called protoplasts, in the active disease process of this patient is discussed in relation to the criteria for the implication of protoplasts in the disease process. Several explanations as to what caused the in vivo formation of protoplasts of C. tropicalis in this patient are discussed. PMID- 4160232 TI - Use of dihydrostreptomycin for the isolation of auxotrophic mutants of Pseudomonas aeruginosa. PMID- 4160233 TI - Papain-treated globulins in specific and cross-reacting immunofluorescent staining. AB - Jones, Wallis L. (Communicable Disease Center, Atlanta, Ga.), and J. W. Foster. Papain-treated globulins in specific and cross-reacting immunofluorescent staining. J. Bacteriol. 91:984-986. 1966.-Cross-reaction staining with preimmune and specific fluorescein conjugates to Corynebacterium diphtheriae was studied by use of papain-treated antisera. Enzyme-treated antisera were labeled and chromatographically separated into three fractions. Fractions were tested by both direct and inhibition fluorescent-antibody procedures. The cross-reaction staining was found in all three fractions, whereas specific staining was found in only two fractions. PMID- 4160235 TI - Three different types of mate-killer (mu) particle in Paramecium aurelia (syngen 1). PMID- 4160234 TI - Nonabsorbable rabbit anti-Salmonella typhimurium antibody as detected by the complement-mediated bactericidal reaction. AB - Herzberg, Mendel (University of Florida, Gainesville), Kathryn V. Kenny, and John B. Robbins. Nonabsorbable rabbit anti-Salmonella typhimurium antibody as detected by the complement-mediated bactericidal reaction. J. Bacteriol. 91:1548-1555. 1966.-A portion of antibody active in the complement-mediated bactericidal reaction against Salmonella typhimurium from hyperimmune rabbit serum has been shown to be nonabsorbable by repeated serial absorptions with whole heat-killed or living bacteria. The first two absorptions remove 90 to 95% of the activity, but 1 to 5% cannot be removed by subsequent absorptions. The nonabsorbable antibody appears to be a macroglobulin by density-gradient centrifugation and by comparison of activity and absorbability of purified gamma-M and gamma-G immune globulins. Alternative hypotheses involving low avidity antibody or antibody to minor cell antigenic components are offered in explanation of the phenomenon. PMID- 4160237 TI - A comparison of intrathecal alcohol and phenol. PMID- 4160236 TI - A histochemical analysis of the proteins in the larval fat body of Sarcophaga bullata. PMID- 4160238 TI - Effect of mitomycin C on protein synthesis in human neoplastic cell lines. PMID- 4160239 TI - [Contribution to clone isolation of foot-and-mouth disease virus with the plaque method]. PMID- 4160240 TI - [Functional changes of giant chromosomes under conditions of inhibited RNA synthesis]. PMID- 4160241 TI - [A new human serum polymorphism demonstration by the use of tanned erythrocytes adsorbing beta-1C globulin]. PMID- 4160242 TI - Cryosurgical treatment of the prostate. PMID- 4160243 TI - Leucine aminopeptidase activity in benign hyperplastic and malignant prostatic tissue. PMID- 4160244 TI - [Tests for the identification of falciform erythrocytes]. PMID- 4160245 TI - Relation between Gm(f) and the structure of the gamma-globulin molecule. PMID- 4160246 TI - The influence of environmental temperature on thyroid, adrenal, and water metabolism in the newborn human infant. PMID- 4160247 TI - Elevation of protein-bound iodine in an 8-year-old due to transplacental passage of an organic iodine dye. PMID- 4160249 TI - [The significance of pre-existing kidney damage in late pregnancy gestoses]. PMID- 4160248 TI - The nature of the cell membrane receptor for the agglutination factor present in the sera of tumor patients and pregnant women. PMID- 4160250 TI - [Immunoelectrophoretic studies on urinary proteins in inflammatory and degenerative kidney diseases]. PMID- 4160251 TI - [Contribution to the pathological histology of lacrimal glands. Incidence of mast cells in the lacrimal glands]. PMID- 4160253 TI - [Metachromasia and metachromatic colorations]. PMID- 4160252 TI - Controlled study of survival of patients with clinically inoperable lung cancer treated with radiation therapy. PMID- 4160254 TI - The interaction of human serum protein fractions with the starch-iodine complex. PMID- 4160255 TI - Studies on the antigenic capacity of chicken and bovine cytochrome C. PMID- 4160256 TI - Effect of reduction and alkylation on allergen-combining properties of reaginic antibody. PMID- 4160257 TI - Physicochemical properties of reaginic antibody. 1. Association of reaginic activity with an immunoglobulin other than gammaA- or gammaG-globulin. PMID- 4160258 TI - An immunofluorescent study of pathogenic mechanisms in glomerular diseases. PMID- 4160259 TI - [The electrophoretic picture of blood proteins in the premature infant. I]. PMID- 4160260 TI - The quantitation of human serum albumin by immunoelectrophoresis. PMID- 4160261 TI - Cholinesterase and tyrosinase activity in malignant melanoma. PMID- 4160262 TI - Ultrastructure of benign peripheral nerve sheath tumors. PMID- 4160263 TI - [Evaluation of post-extrasystolic modifications of the T wave]. PMID- 4160264 TI - ["Pathologic" ventricular extrasystole in diagnosis of myocardial necrosis]. PMID- 4160265 TI - P-5227: a 6-7-6 tricyclic antipsychotic compound. PMID- 4160266 TI - Effect of actinomycin and mitomycin on fibroin synthesis in the posterior silkgland of Bombyx mori. PMID- 4160267 TI - Simultaneous resin uptake studies of labeled thyroxine and triiodothyronine in thyroid disease. PMID- 4160268 TI - Gamma-globulin in the prophylaxis of posttransfusion hepatitis. PMID- 4160269 TI - [Follow-up treatment of fractures and fracture-induced disease]. PMID- 4160271 TI - [Modification 3 of Graham-Knoll peroxidase reaction for the demonstration of Auer bodies and nucleoli]. PMID- 4160270 TI - [Permeability of the margins of dental fillings controlled by crystal violet]. PMID- 4160272 TI - [Radioautographic studies on the RNA and protein metabolism of immature cells in acute leukemia. Preliminary report]. PMID- 4160273 TI - [Evaluation of the success of methods of silver impregnation in sections of the peripheral nervous system]. PMID- 4160274 TI - Submicroscopical structure of adenoid cystic carcinoma of salivary glands. PMID- 4160275 TI - Phenol reaction of collagen fibres and acid mucopolysaccharide content of connective tissue. PMID- 4160276 TI - Histochemical examination of vaginal epithelium and endometrium with special reference to mucopolysaccharides. PMID- 4160277 TI - [Development of keratinization of human epidermis with special reference to the barrier]. PMID- 4160278 TI - [Nomenclature of genetic factors supported by human immunoglobulins]. PMID- 4160279 TI - Management of far-advanced carcinoma of the lung. PMID- 4160280 TI - Specificity of immunological tolerance induced in the rabbit to genetic determinants of human gamma-G globulin. PMID- 4160281 TI - The immunoglobulin sequence. II. Histological effects of the suppression of gamma M and gamma-G antibody synthesis. PMID- 4160282 TI - The ultrastructure of human amyloid as revealed by the negative staining technique. PMID- 4160283 TI - The penetration of thorotrast into brain spaces following osmium, glutaraldehyde, and hydroxyadipaldehyde fixation. PMID- 4160284 TI - A comparative study of the palliative results of the indwelling esophageal tube. PMID- 4160285 TI - Thyroidectomy of the goat. PMID- 4160286 TI - Microsomal epoxidation of cyclodiene insecticides. PMID- 4160287 TI - [Changes in the serum proteins after fractionated irradiation of the thymus with low doses]. PMID- 4160288 TI - The shoulder-hand syndrome. PMID- 4160289 TI - [Distribution of the active dye bright red in the muscle tissue and the medium]. PMID- 4160290 TI - [Distribution to phenol red between muscles and the medium in solutions of various osmotic strength]. PMID- 4160291 TI - [Prevention of recurrence of operated goiter and the treatment of postoperative myxedema with triiodothyronine]. PMID- 4160292 TI - [Considerations on operative risk in prostatic hypertrophy]. PMID- 4160293 TI - Carbon monoxide levels in city driving. PMID- 4160294 TI - Biological effects of atmospheres contaminated by auto exhaust. PMID- 4160295 TI - Horse anti-SI immunoglobulins. I. Properties of gamma-M-antibody. PMID- 4160296 TI - [Histochemical analysis of PAS-positive substances in the reticular cells of the vermiform process in rabbits]. PMID- 4160297 TI - [Dynamics of morphologic changes in the innervation system of the meninges in dogs during severe forms of acute radiation sickness]. PMID- 4160298 TI - [Some indices of lipid metabolism and changes in the blood circulation in dogs during experimentally induced atherosclerosis without the use of cholesterol]. PMID- 4160299 TI - [Cabbage goitrogens and the possibilities of reducing their level by interventions during the vegetation period]. PMID- 4160300 TI - [A synthesis of 2-methyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-henzo[a] quinolizine-3-methanol phenylcarbamate. (Studies on the synthesis of heterocyclic compounds. 128]. PMID- 4160301 TI - Inactivity of purified reovirus RNA as a template for E. coli polymerases in vitro. PMID- 4160302 TI - Differential activity of allelic gamma-globulin genes in antibody-producing cells. PMID- 4160303 TI - Carcinoma of the oesophagus, with special reference to the upper third. I. Clinical considerations. PMID- 4160304 TI - Carcinoma of the oesophagus, with special reference to the upper third. II. Physical considerations. PMID- 4160305 TI - [2,3-PGase deficiency as a possible cause of increased ATP-content]. PMID- 4160306 TI - Hereditary high ATP content of human erythrocytes. PMID- 4160307 TI - [On the purification and characterization of 2,3-PGase of red blood cells]. PMID- 4160308 TI - [On the effect of glycolytic intermediary products on the 2,3-PGase activity of red blood cells]. PMID- 4160309 TI - [Phosphoglyceric acid changes in reticulocytes and erythrocytes of sheep]. PMID- 4160310 TI - [Problems of erythrocyte metabolism in anemias with pyruvate kinase deficiency]. PMID- 4160312 TI - [Carbohydrate metabolism of red blood cells in the dog in magnesium deficiency]. PMID- 4160311 TI - [Pyruvate kinase deficiency and some problems of glycolysis regulation]. PMID- 4160313 TI - [On erythrocyte glycolysis]. PMID- 4160314 TI - Limiting role of adenine nucleotide in the glycolysis of the human erythrocyte. PMID- 4160315 TI - [Investigations on an inosine kinase in red blood corpuscles]. PMID- 4160316 TI - [Investigations on the behavior of GOT in erythrocytes of newborn infants and older children]. PMID- 4160317 TI - [Acetylation of aromatic amines in red blood cells]. PMID- 4160318 TI - [Enzymatic regulation mechanisms on the level of lactate oxidoreductase]. PMID- 4160319 TI - [Behavior of glycine, alanine and glutamate in reticulocytes during brief incubation]. PMID- 4160320 TI - [Metabolism of amino acids in the reticulocyte]. PMID- 4160321 TI - [Serine metabolism in the reticulocyte]. PMID- 4160322 TI - [Effect of methylene blue on the metabolism of substrate in the reticulocyte]. PMID- 4160323 TI - [On the nature of the easily split-off iron]. PMID- 4160324 TI - On the correlation between specific activities of hem and globin and of their ratio with the hemoglobin content in duck blood incubated in vitro with 2-14C glycine. PMID- 4160325 TI - [On the maturation of reticulocytes under simple in vitro conditions]. PMID- 4160326 TI - [On purification of the Fe-flavin enzyme inhibitor from reticulocytes]. PMID- 4160327 TI - Factors influencing the preservation of red cell ATP on storage. PMID- 4160328 TI - The separation of glucose-6-phosphate dehydrogenase deficient erythrocytes from blood of heterozygotes for glucose-6-phosphate dehydrogenase deficiency. PMID- 4160329 TI - [On bound glutathione in erythrocytes]. PMID- 4160330 TI - [The difference between the mechanism of the effect of hydroxylamine and of phenylhydroxylamine on the metabolism of erythrocytes]. PMID- 4160331 TI - [Determinations of GSSG in red blood cells]. PMID- 4160332 TI - [On the action mechanism of phenylhydrazine on SH enzymes]. PMID- 4160333 TI - Fluorescent protein tracer studies in allergic reactions. 3. Distinguishing characteristics of direct and reversed passive Arthus reactions: the influence of size of antigen and of animal species. PMID- 4160334 TI - The immunogenicity of cephalosporin derivatives and their cross-reaction with penicillin. PMID- 4160336 TI - Characterization of two different agglutinators in the latex fixation test, occurring in normal human sera. PMID- 4160335 TI - Thymic involution and recovery: immune responsiveness and immunoglobulins after neonatal prednisolone in rats. PMID- 4160337 TI - The replication of bacteriophage MS2. V. Proteins specifically associated with infection. PMID- 4160338 TI - Variations in the heavy polypeptide chain structure of gamma myeloma immunoglobulins from an inbred strain of mice and a hypothesis as to their origin. PMID- 4160339 TI - Gamma globulin in asthmatic children. PMID- 4160340 TI - Experimental arthritis associated with auto-immunization to inflammatory exudates. PMID- 4160341 TI - [Identification of the gamma A-gloublins, kallikrein and transferrin in the human bronchial mucosa]. PMID- 4160342 TI - [Study of the metabolism of gamma globulins in the aged conducted with I-131 labelled gamma globulins. (Primary results)]. PMID- 4160343 TI - A rapid staining method giving sharp nuclear definition in frozen sections. PMID- 4160344 TI - Cytological staining procedures. PMID- 4160346 TI - [Diagnostic difficulties and adverse effects of prednisone in amyloid nephrosis with beta globulin paraproteinemia]. PMID- 4160345 TI - [Role of polychromes in some neuropathologic studies]. PMID- 4160347 TI - Some observations on thyroid-adrenocortical interrelationships. PMID- 4160348 TI - Enhanced protection with the use of gamma globulin proteins in the treatment of tourniquet shock with plasma expanders. PMID- 4160349 TI - [Comparative autoradiographic investigations on the protein metabolism of the cochlea and of the equilibrium mechanism]. PMID- 4160350 TI - The early years of the Academie des Sciences. PMID- 4160351 TI - John Dalton. PMID- 4160352 TI - The cytoplasmic control of gene activity. PMID- 4160353 TI - Cases of lymphoma treated with human tissue antisera. PMID- 4160354 TI - The shoulder-hand syndrome: observations and review of the literature. PMID- 4160355 TI - Leptospirosis in kennel dogs. PMID- 4160356 TI - Effect of dietary protein level prior to acute starvation on serum proteins in the rat. PMID- 4160357 TI - Adsorption and diffusion of gamma-globulin during passive sensitization of chopped guinea-pig lung. PMID- 4160358 TI - Gamma globulin synthesis on ribosomes and ribosomal aggregates. PMID- 4160359 TI - [A complex method for silver impregnation with Voelgen's reaction]. PMID- 4160360 TI - [Method for detecting on electrophoregrams and chromatograms stains from substances absorbing ultraviolet rays in the zone of 254-260 mmk (photography in ultraviolet light)]. PMID- 4160361 TI - [Detection of similar antigenic determinants in embryo-specific alpha globulins in man and some animals]. PMID- 4160362 TI - [Effect of actinomycin C on liver regeneration in mice]. PMID- 4160363 TI - [Studies on the benzoheterocyclic compounds. 3. Synthesis of benzoxazinone derivatives. I]. PMID- 4160364 TI - [Studies on the benzoheterocyclic compounds. IV. Synthesis of benzoxazolinone and benzoxazione derivatives. II]. PMID- 4160365 TI - The complications of endoesophageal tubes. PMID- 4160366 TI - [Effectiveness of treatment with gamma globulin in children infected with viral hepatitis]. PMID- 4160367 TI - [4-Oxo-5-methyl-proline, a component of actinomycin Z-1]. PMID- 4160368 TI - [Extensive and palliative surgical interventions in lung cancer]. PMID- 4160369 TI - Achiotin, an extract of achiote seeds (Bixa orellana L.), as a histologic stain for lipids. PMID- 4160370 TI - Basic fuchsin-tannic acid; a one-solution stain for spore walls in fungi. PMID- 4160371 TI - Vital staining by trypan blue; its selectivity for olfactory receptor cells of the brown bullhead, Ictalurus natalis. PMID- 4160372 TI - Iron-hematoxylin and safranin O as a polychrome stain for epon sections. PMID- 4160373 TI - Triple silver impregnation for selective staining of avian nerves. PMID- 4160375 TI - Counterstaining solution for sections stained with Golgi-Cox method. PMID- 4160374 TI - Gross demonstration of the mammalian atrioventricular bundle by a periodic acid Schiff procedure. PMID- 4160376 TI - Studies of plasma protein electrophoresis in canine renal homotransplantation. PMID- 4160377 TI - A case of autoimmune haemolytic anaemia, thrombocytopenia and Landry-Guillain Barre syndrome. PMID- 4160378 TI - Effect of growth hormone and thyrotropin upon deiodination of diiodotyrosine by hypophysectomized rat thryoid and liver. PMID- 4160379 TI - Thyroidal iodide tranpsort. 8. PMID- 4160380 TI - Early enhancement by thyrotropin of thyroid organification of circulating iodide. PMID- 4160381 TI - [Contribution to the fat specificity of sudan black B and other red sudan dyes in pure substances]. PMID- 4160382 TI - [On the indirect detection of non-lipid substances with sudan black B]. PMID- 4160383 TI - Immunology and morphology of acute post-streptococcal glomerulonephritis. PMID- 4160384 TI - [Morphological bases of the blood-brain barrier, Principles of the development of the problem up to the present time]. PMID- 4160385 TI - [Comparative study of the electrophoretic mobilities of serum and urinary myelomatous proteins]. PMID- 4160386 TI - Fluorometric estimation of antigens (antibodies). PMID- 4160387 TI - [Synthesis of ribonucleic acids in whole embryos and in the isolated ectoderm of Triturus alpestris]. PMID- 4160388 TI - [Actinomycins, XXVI; syntheses of actinomycins and actinomycin-like chromopeptides, I. Actinocinyl-bis-L-threonine]. PMID- 4160389 TI - Average evoked potentials and reaction times to visual stimuli. PMID- 4160390 TI - Comprehensive spectral analysis of human EEG generators in posterior cerebral regions. PMID- 4160391 TI - Some characteristics of average steady-state and transient responses evoked by modulated light. PMID- 4160392 TI - Inter-areal differences in the direct cortical response of the middle suprasylvian gyrus of the cat. PMID- 4160393 TI - Flicker-induced cardiac arrest in a patient with epilepsy. PMID- 4160394 TI - Electrophysiological findings in cortical blindness. Report of a case. PMID- 4160395 TI - Selective suppression of delayed hypersensitivity by the induction of immunologic tolerance. AB - Administration of DNP-BGG to newborn guinea pigs resulted, in more than half of the animals, in the specific suppression of delayed hypersensitivity to DNP-BGG and BGG, as shown after immunization with DNP-BGG in complete Freund's adjuvant. In contrast, all animals formed antibodies to DNP-BGG, whether or not delayed hypersensitivity to this antigen was present. No difference in antibody titers was found between pretreated and control animals. All animals had antibodies reacting specifically to the hapten DNP, and most of them to the carrier protein BGG, whether or not delayed hypersensitivity to the carrier protein was present. Furthermore, some animals with and without positive 24 hr skin test to DNP-BGG had antibodies with a combined hapten-carrier protein specificity to this antigen, i.e., a specificity which is similar to that of delayed hypersensitivity. Thus, delayed hypersensitivity and antibody formation to similar antigenic determinant were differently affected by injection of antigen in the neonatal period. The finding that delayed hypersensitivity and antibody formation could be dissociated by the induction of immunologic tolerance supports the assumption that delayed hypersensitivity and antibody formation are different immune processes which are not necessarily linked together. PMID- 4160396 TI - Characteristics of streptococcal group-specific antibody isolated from hyperimmune rabbits. AB - Intravenous immunization of New Zealand red rabbits with streptococcal group specific bacterial vaccines yielded sera which possessed markedly elevated gamma globulin. The sera of one rabbit immunized with Group A-variant vaccine possessed 55 mg/ml of gamma-globulin. The bulk of this gamma-globulin, identified as gamma(G)-globulin, was homogeneous by zone electrophoresis and of specificity directed against the Group A-variant carbohydrate antigen. L chains isolated from specific antibody obtained from an immune precipitate were distributed as a single band on starch gel electrophoresis, whereas the normal gamma-globulin traveled as a diffuse smear. These data suggest that the rabbit streptococcal Group A-variant antibodies possess a limited range of physicochemical properties and electrophoretic mobility compared to that generally observed for the normal complement of gamma-globulin. PMID- 4160397 TI - The IgA system. I. Studies of the transport and immunochemistry of IgA in the saliva. AB - 1. Five patients with congenital or acquired agammaglobulinemia, lacking detectable IgA in serum or saliva, were transfused with 1 to 2 liters of normal plasma. In 2 of these patients IgA was demonstrated in parotid saliva collected after transfusion, but in none of the 5 was salivary IgG or IgM found. This observation indicates the selective transport of IgA into saliva. 2. The observation by others of an immunochemical difference between serum and sahvary IgA globulin was confirmed. In contrast to serum IgA, salivary IgA is attached to a protein having antigenicity which migrates as a gamma(1) globulin. We have termed this protein component "transport piece". 3. The transport piece has been found in an unbound form in the saliva of persons completely lacking IgA: agammaglobulinemic patients, ataxia-telangiectasia patients, a healthy person lacking IgA, and a newborn infant. Free transport piece still occurs in the normal child's saliva after IgA production begins. By adulthood there is usually no free transport piece in the saliva. 4. Heat-aggregated salivary IgA, like heat aggregated serum IgA, does not fix complement. 5. Our findings offer support for the view that there is a distinct local antibody system for the protection of the mucous surfaces. PMID- 4160398 TI - Studies on the effect of the carrier molecule on antihapten antibody synthesis. I. Effect of carrier on the nature of the antibody synthesized. AB - 1. Fluorescence quenching has been calibrated, by comparison with equilibrium dialysis, for measurement of antibody-hapten association constants with guinea pig antibody to the 2,4-dinitrophenyl (DNP) determinant. The maximum quenching with all sites occupied which gave best agreement with equilibrium dialysis was found to be 100%. 2. The carrier to which the DNP-hapten is coupled influences significantly the amount, class (gamma(1) or gamma(2)), and affinity of the antibody of DNP specificity made by individual guinea pigs. 3. The affinities of gamma(1)- and gamma(2)-antibodies from individual guinea pigs are generally very similar. 4. Precipitin curves with gamma(1)-antibodies show more marked inhibition of precipitation in antigen excess than do precipitin curves with the less charged gamma(2)-antibodies, indicating the importance of nonspecific forces in the precipitation reactions. PMID- 4160399 TI - Studies on the effect of the carrier molecule on antihapten antibody synthesis. II. Carrier specificity of anti-2,4-dinitrophenyl-poly-l-lysine antibodies. AB - Equilibrium measurements of interactions of anti-DNP antibodies, prepared using DNP-PLL and several DNP-proteins for immunization, with DNP(0.6)-PLL(240) and with the univalent hapten, epsilon-DNP-L-lysine, were made utilizing the technique of fluorescence quenching. Carrier specificity of anti-DNP-PLL antibodies was demonstrated by a higher average intrinsic association constant (K(0)) of anti-DNP-PLL antibodies with DNP(0.6)-PLL(240) than with epsilon-DNP-L lysine. The free energy contribution of the PLL carrier to the interaction of intact anti-DNP-PLL antibodies with DNP(0.6)-PLL(240) was from -0.8 to -2.1 kcal/mole. On the other hand, intact anti-DNP-protein antibodies displayed a lower energy of interaction with DNP(0.6)-PLL(240) than with epsilon-DNP-L-lysine of up to +2.4 kcal/mole. Fab' fragments of both anti-DNP-PLL and anti-DNP-BGG antibodies have K(0)'s with epsilon-DNP-L-lysine identical to the K(0)'s of the intact anti-DNP antibodies from which they were prepared. However, K(0) of interaction of Fab' fragments with DNP(0.6)-PLL(240) (a large proportion of the conjugated PLL molecules in this preparation bear more than one DNP group) is considerably lower than that of the intact antibody. Thus a cooperative effect in the binding of bivalent antibody and bivalent (or greater) antigen exists and is of the order of -1.2 to -2.0 kcal/mole of IgG antibody. Although the direct contribution of the carrier to the interaction of Fab' fragment of anti-DNP-PLL and DNP(0.6)-PLL(240) is -0.4 kcal/mole, the energy of carrier specificity, based upon consideration of cooperative effects and of repulsion of anti-DNP-protein antibodies for portions of the DNP-PLL determinants, is of the order of -3 kcal/mole (approximately 30% of total binding energy). PMID- 4160401 TI - Deiodination of the 131-I-labelled substances of blood serum. I. PMID- 4160400 TI - Immunoglobulin isoantigens (allotypes) in the mouse. II. Allotypic analysis of three gammaG2-myeloma proteins from (NZB x BALB/c)F1 hybrids and of normal gammaG2-globulins. AB - Further analysis of the isoantigens (allotypes) of 2 classes of normal mouse immunoglobulins, gammaG(2a) and gammaG(2b), has shown a minimum of 10 specificities for the Ig-1 locus (controlling gammaG(2a)-antigens) and 3 specificities for the Ig-3 locus (controlling gammaG(2b)-antigens). Three gammaG(2)-myeloma proteins of plasma cell tumors induced in (NZB x BALB/c)F(1) mice have been analyzed for the isoantigens they carry. NZB mice are genotypically Ig-1(e) Ig-3(e), while BALB/c are Ig-1(a) Ig-3(a). Two of the myeloma proteins are gammaG(2a)-globulins. One of these, GPC-7, carries all the isoantigenic specificities of the Ig-1(e) allele while the other, GPC-8, carries all the isoantigenic specificities of the Ig-1(a) allele. Thus only one of the parental alleles of the mouse in which the tumor arose is expressed in each of these myeloma proteins. The third myeloma protein GPC-5, also carries the antigens of only one parental strain (NZB). However GPC-5, a gammaG(2b)-globulin, carries only one of the Ig-3 specificities normally associated with gammaG(2b) globulins of NZB. Most remarkably it also carries one Ig-1 specificity normally associated with gammaG(2a)-globulins of NZB. This is the first analyzed mouse myeloma shown (a) to express some but not all the antigenic specificities normally associated with an allele and (b) to carry antigenic specificities controlled by two distinct immunoglobulin loci. The implications of these findings are discussed in relation to the genetic control of immunoglobulins. PMID- 4160402 TI - Deiodination of the endogenously 131-I-labelled substances in blood serum. II. PMID- 4160403 TI - The use of the Bodian protargol method for the demonstration of parathyroid gland secretory granules in tissue fixed in chromate containing fixatives. PMID- 4160404 TI - The use of human immunoglobulin. Report of a WHO Expert Committee. PMID- 4160405 TI - [Diapositives, their preparation and significance in the illustration of scientific lectures]. PMID- 4160406 TI - An autoradiographic study of the RNA and protein metabolism of normal plasma cells and phytohaemagglutinin-stimulated lymphocytes. PMID- 4160407 TI - The routes for bulk drainage of aqueous humour in the vervet monkey (Cercopithecus ethiops). PMID- 4160408 TI - [On the "alpha 2 type" plasmocytoma. Case contribution]. PMID- 4160409 TI - Iodine deficiency in two endemic goiter areas of central and southern Italy. PMID- 4160410 TI - Quantitative studies of iodine metabolism after long-term treatment of thyrotoxicosis with antithyroid drugs. PMID- 4160411 TI - Disinfection of contra-angles and handpieces using a benzalkonium towelette. PMID- 4160412 TI - The need for continuing education. PMID- 4160413 TI - Dental care for half a million pre-schoolers. PMID- 4160414 TI - ADA and AADS testify on bill to aid health auxiliary education. PMID- 4160415 TI - Does the intermediate plexus of periodontal ligament exist? PMID- 4160416 TI - The production of slides and filmstrips. PMID- 4160417 TI - The C-terminal peptide of the heavy chain of the rabbit immunoglobulin IgG. PMID- 4160418 TI - Preparation and antibacterial activity of isatogens and related compounds. PMID- 4160419 TI - The new "rubella syndrome". PMID- 4160420 TI - [Detection of pathologic heart changes through measurement of R and T vectors in the sagittal plane of the body by means of leads of points of the "horizontal heart triangle"]. PMID- 4160422 TI - The preparation of nucleotide-protein conjugates: carbodiimides as coupling agents. PMID- 4160421 TI - [On vital stains of cytoplasmic structures in blood and tissue cells]. PMID- 4160423 TI - The production of antibodies to mononucleotides, oligonucleotides and DNA. PMID- 4160424 TI - Immunoglobulin patterns of antibodies against Brucella in man and animals. PMID- 4160425 TI - Immunologic unresponsiveness in the adult guinea pig. II. The kinetics of unresponsiveness. PMID- 4160426 TI - The use of lead as a tracer in ultrastructural research. PMID- 4160427 TI - [Gamma globulin in the saliva and salivary glands: identification and immuno histochemical localization]. PMID- 4160428 TI - All human beings start life as babies. PMID- 4160429 TI - Vacuoles in synovial fluid leukocytes. PMID- 4160430 TI - [Determination of total iodine and hormonal iodine in the blood serum by use of an autoanalyzer]. PMID- 4160431 TI - [Free histamine content in the groove caused by hanging as an in vivo reaction]. PMID- 4160434 TI - [Studies on histamine in human saliva (II)]. PMID- 4160435 TI - Serological analysis of some enzymes present in pseudorabies virus-infected and noninfected cells. PMID- 4160436 TI - Macroglobulins and the Sia water test. PMID- 4160437 TI - Anti-gamma-globulin and antinuclear factors in chronic bronchitis. Relation to disease course and hyperglobulinemia. PMID- 4160438 TI - [Changes of blood coagulation factors in long-term treatment with anticoagulants and in liver cirrhosis]. PMID- 4160439 TI - Lack of gamma A-immunoglobulin in serum of patients with steatorrhoea. PMID- 4160440 TI - Use of polyethylene glycol and phenol red as unabsorbed indicators for intestinal absorption studies in man. PMID- 4160441 TI - Selective and specific inhibition of 24-hour skin reactions in the guinea-pig. II. The mechanism of immune deviation. PMID- 4160442 TI - Evidence for a humoral thymic factor in rabbits. PMID- 4160443 TI - Isolation of purified H and L polypeptide chains from guinea-pig gamma-2 immunoglobulin after mild reduction. PMID- 4160444 TI - Properties of fragments of human Wassermann antibodies. PMID- 4160445 TI - Effect of mercaptans and other agents on the human complement component beta-1c globulin. PMID- 4160446 TI - In vitro synthesis of gamma M-like globulin by various chick embryonic cells. PMID- 4160447 TI - [Studies on the mechanism of the amine liberating action of proteolytic enzymes in blood platelets]. PMID- 4160448 TI - Phosphatase activity in Pasteurella multocida. A test for differentiation between var. mammalium and var. avium of this organism. PMID- 4160450 TI - The structure of Vi-phage II. PMID- 4160451 TI - Electron microscopic studies of Vi-phage II adsorption on Salmonella typhi. PMID- 4160449 TI - Exoenzymes in fungi degrading lignin. II. Demethoxylation of lignin and vanillic acid. PMID- 4160452 TI - Corticosteroidal stress and Newcastle disease virus infection. PMID- 4160453 TI - Enzymic activation of D-glutamic acid and D-alanine in Mycobacterium phlei. PMID- 4160454 TI - The intestinal microflora of Cetonia aurata L. (Lamellicorni) larvae fed different diets. PMID- 4160455 TI - The intestinal microflora of Oryctes nasicornis L. larvae. PMID- 4160456 TI - Studies on the role of microorganisms in the life of cultivated plants. 3. Origin of the bacterial substances stimulating the growth of plants. PMID- 4160457 TI - Methane fermentation of sewage sludge. 3. The rate of methane formation from short chain fatty acids. PMID- 4160458 TI - The effect of environmental temperature on the course of influenza virus infection in mice and frogs. PMID- 4160459 TI - [Relation of the biosynthesis of nonspecific gamma-globulins and antibodies in vitro and effects of antigens on these processes]. PMID- 4160460 TI - [Effect of ultrasonic waves on the structure and immunobiological activity of gamma-globulin]. PMID- 4160461 TI - Audiovisual methods in continuing education. PMID- 4160462 TI - Childhood hyperthyroidism. Report on 39 cases. PMID- 4160463 TI - [Periarthritis humeroscapularis in the roentgen picture of the shoulder]. PMID- 4160464 TI - [The Sudeck syndrome]. PMID- 4160465 TI - [The shoulder-arm syndrome]. PMID- 4160467 TI - Observations on the morphological changes in Myco. leprae in leprosy. PMID- 4160466 TI - [Therapeutic results and intrathoracic radiation reactions in the therapy of bronchial carcinoma by fast electrons. II. Radiation reactions]. PMID- 4160469 TI - [Expressive sound symbolism. A test of the hypothesis with 25 languages]. PMID- 4160468 TI - Lipodystrophy of mesenteric fat. PMID- 4160470 TI - [Rheumatoid arthritis treated by administration of imuran and actinomycin-c]. PMID- 4160472 TI - [Studies on benzoheterocyclic compounds. V. Synthesis of benzoxazolinone and benzoxazinone derivatives. 3]. PMID- 4160471 TI - [Biochemical findings in acute nitrogenzol poisoning in man]. PMID- 4160473 TI - [Cytochemical studies in acute leukoses]. PMID- 4160474 TI - [The immunoglobulins. Recent concepts. Their value in tropical pathology]. PMID- 4160475 TI - [Spray reagents with double function in thin layer chromatography of lipids]. PMID- 4160476 TI - Today and tomorrow. PMID- 4160477 TI - "Simplified clinical photography". PMID- 4160478 TI - Localization of arbutin in Pyrus by means of alkaline p-phenylenediamine. PMID- 4160479 TI - [Immunoelectrophoretic studies on meconium]. PMID- 4160480 TI - Familial chronic discoid lupus erythematosus and hypergammaglobulinemia. PMID- 4160481 TI - Mucin-producing carcinoma of the breast. Tissue culture, histochemical and electron microscopic study. PMID- 4160482 TI - Patient education. PMID- 4160483 TI - Educational material. PMID- 4160484 TI - The relation between isolated human amyloid fibrils and human gamma-globulin and its subunits. PMID- 4160485 TI - Difference in mechanism of viral neutralization under in vitro and in vivo conditions. PMID- 4160486 TI - [Liver and kidney profiles supplementing the 2-phase radioiodine tests in thyroid function diagnosis]. PMID- 4160487 TI - Skull adapted for teaching roentgenographic technique. PMID- 4160488 TI - [On the microstructure of argentaffin cells and other forms of Feyrter's clear cells in the rabbit stomach]. PMID- 4160489 TI - The relative proportion of pre-enterochromaffin (argyrophile) and enterochromaffin (argentaffin) cells in the gastro-intestinal tract of human foetuses. PMID- 4160490 TI - [The inhibition threshold of nucleic acid synthesis and division by actinomycin in Tetrahymena pyriformis]. PMID- 4160491 TI - Studies in alpha 1-antitrypsin deficiency. PMID- 4160492 TI - A rapid procedure for preparing fluorescein-isothiocyanate-labeled anti-Anaplasma gamma globulin. PMID- 4160493 TI - An improved staining method for Neorickettsia helminthoeca. PMID- 4160494 TI - Localization of hemosiderin. Histochemical observations of hemosiderin and iron associated pigment in rats as related to the source of iron. PMID- 4160495 TI - Planning dental illustrations. PMID- 4160496 TI - [Carbimazolum. (Carbimazole)]. PMID- 4160497 TI - Protein-bound iodine (pbi) in human amniotic fluid. PMID- 4160499 TI - Human immunoglobulins--a guide to nomenclature and clinical application. PMID- 4160498 TI - [Contribution to hereditary blepharochalasis]. PMID- 4160500 TI - The proliferation and migration of the attachment epithelium on the cemental surface of the rat incisor. PMID- 4160501 TI - Acid muopolysaccharides in the oral epithelium. PMID- 4160502 TI - Histamine liberation by gastric mucosa of pylorus-ligated rats damaged by acetic or salicylic acids. PMID- 4160503 TI - A study of gamma globulins in cholera. PMID- 4160504 TI - Dissociation of esterolytic and clotting activities of thrombin by trypsin binding macroglobulin. PMID- 4160505 TI - Endotoxin cytotoxicity: role of cell-associated antibody. PMID- 4160506 TI - Teratogenic effect of chlormadinone acetate in mice and rabbits. PMID- 4160507 TI - Passive immune hemolysis: titration of hemolytic anti-protein antibody using bis diazotized-benzidine to couple antigen to erythrocytes. PMID- 4160508 TI - Effect of thymectomy in newborn rats infected with Moloney virus. PMID- 4160509 TI - [So-called spontaneous prostatic hypertrophy in dogs and experimental hypertrophy induced by estrogens and androgens with reference to histo-enzymologic behavior]. PMID- 4160510 TI - Sudanophilic aortic lesions in chimpanzees. PMID- 4160511 TI - Effect of passive immunization on sensitizing action of Haemophilus pertussis. 1. Development of increased sensitivity to reinjection of homologous antigens. PMID- 4160512 TI - Content of embryo-specific alpha-globulin in fetal and neonatal sera and sera from adult humans with primary carcinoma of the liver. PMID- 4160513 TI - Effect of anticoagulants on blood viscosity, circulation time and the capillaroscopic picture. PMID- 4160514 TI - [Antigammaglobulin factors in myeloma and macroglobulinemia]. PMID- 4160515 TI - Controlled trials of hyperbaric oxygen and tracheal intubation in asphyxia neonatorum. PMID- 4160516 TI - Natural rabies in a laboratory monkey. PMID- 4160517 TI - The natural history of haemorrhage from oesophageal varices. PMID- 4160519 TI - Reovirus 3 and lymphoblastic lymphomas. PMID- 4160518 TI - Disturbance of swallowing after tracheostomy. PMID- 4160520 TI - Arterioles in hypertension. PMID- 4160521 TI - Hepatic cirrhosis and the lungs. PMID- 4160522 TI - Diagnosis of respiratory virus infections. PMID- 4160523 TI - Drugs and retroperitoneal fibrosis. PMID- 4160524 TI - Psychiatric dicta. PMID- 4160525 TI - YY chromosomes and Klinefelter's syndrome. PMID- 4160526 TI - [Ultrastructure of the normal and adenomatous prostate]. PMID- 4160527 TI - Disturbances of the immunoglobulins. PMID- 4160529 TI - [New morphological problems of kidney diseases]. PMID- 4160528 TI - [Kidney and hypertension]. PMID- 4160530 TI - [On the history of kidney pathology]. PMID- 4160531 TI - [Hemopoietin]. PMID- 4160532 TI - [Electron microscopic findings in experimental kidney infarcts of the rat]. PMID- 4160533 TI - [Ultrastructural cell changes of the tubular epithelium of the kidney after ligation of the kidney veins]. PMID- 4160534 TI - [Electron microscopic picture of experimental kidney cortex necrosis]. PMID- 4160535 TI - [Fine structures of the normal and functionally disturbed nephron]. PMID- 4160536 TI - [On pre-glomerular vascular findings in acute kidney failure in animal experiments and in man]. PMID- 4160537 TI - [Significance of lysosomes for the formal genesis of viomycin nephrosis]. PMID- 4160538 TI - [Electron microscopic and histochemical findings in primary alterations on the distal kidney tubule]. PMID- 4160539 TI - [Electron microscopic investigations on protein storage in the kidney of the mouse]. PMID- 4160540 TI - [Ultrastructural and histochemical early changes in viomycin nephrosis]. PMID- 4160541 TI - [Uptake of radioactive lead 210 by tubulus epithelia of the kidney]. PMID- 4160542 TI - [Polarization-optical investigations on oriented protein incorporation in the kidney]. PMID- 4160543 TI - [The kidney in diseases of the paraprotein-forming lymphoreticular system]. PMID- 4160544 TI - [Kidney changes in hereditary nephropathy with hardness of hearing of the middle ear]. PMID- 4160545 TI - [Changes in kidney tissue following directed high-dosage roentgen irradiation]. PMID- 4160546 TI - [Changes in the kidney caused by SE polyoma virus]. PMID- 4160547 TI - [On dissecting intima hematoma in coronary sclerosis]. PMID- 4160548 TI - [On the significance of blood capillaries for the focal arrangement of so-called hypoxic changes in the heart muscle]. PMID- 4160549 TI - [Investigations on the incidence of muscular collateral connections of the conduction system in premature infants]. PMID- 4160550 TI - [Immunohistochemical investigations on operatively removed heart auricles with special consideration of rheumatic changes]. PMID- 4160551 TI - [Morphological and radiochemical investigations of connective tissue neoplasm in the invasion front of malignant tumors]. PMID- 4160553 TI - [Neoplasms of the nasal cavities of the rat experimentally induced by nitrosamine]. PMID- 4160552 TI - [Neoplastic reticulosis after continuous cytostatic treatment of carcinoma removed by radical surgery]. PMID- 4160554 TI - [Granulomatous giant cell polymyositis and myocarditis in benign thymoma]. PMID- 4160556 TI - [Electron microscopic investigations on allyl alcohol poisoning of the mouse liver]. PMID- 4160555 TI - [Reticulosarcoma of the uterus]. PMID- 4160557 TI - [Electron microscopic investigations on glomus tumors of the glomus tympanicum]. PMID- 4160558 TI - [Histochemical investigations of toxic adenoma of the thyroid gland]. PMID- 4160559 TI - [Relative constancy of the karyotype of a tumor cell strain in various environmental conditions in vitro]. PMID- 4160560 TI - [Enzymological and histochemical investigations on the problem of the origin of tissue leukocytes]. PMID- 4160561 TI - [Cellular infiltration of intercellular substances]. PMID- 4160562 TI - [Histological and serological investigations on the development of immunological competence in the mouse]. PMID- 4160563 TI - [On enzymological and histochemical differentiation of reticuloendothelial spleen cells]. PMID- 4160564 TI - [Genetic reaction differences in the amyloid experiment with mice]. PMID- 4160565 TI - [Lactic acid acidosis and "excess lactate" as yardsticks of irreversible tissue damage]. PMID- 4160566 TI - [Electron microscopic investigations on the storage of organic bound copper in the liver]. PMID- 4160567 TI - [Demonstration of a radioactive substance in the lung of a uranium miner]. PMID- 4160568 TI - [Relationships between mucopolysaccharide synthesis and the submicroscopic structure of the cell (electron microscopic and autoradiographic investigations with tritium-labeled glucose)]. PMID- 4160569 TI - [Investigations on carbohydrate and protein metabolism of growing and aging aortic and tendon tissue]. PMID- 4160570 TI - [On fixation of glutaraldehyde for the demonstration of polysaccharides]. PMID- 4160571 TI - [Autoradiographic investigations on nuclear RNA synthesis in various cell types of the anterior hypophyseal lobe of the rat]. PMID- 4160572 TI - [Immunofluorescence of the ACTH formation sites]. PMID- 4160573 TI - [On the problem of hyperchromasia]. PMID- 4160574 TI - [Experimental investigations on damages of the intestinal mucosa]. PMID- 4160575 TI - [On cytogenetics of mongolism with special reference to the familial form]. PMID- 4160576 TI - [Investigations on lipoids in neurinoma]. PMID- 4160577 TI - [Changes of the enzyme pattern following experimental nerve separation]. PMID- 4160578 TI - [Electron microscopic investigations on Schwann cells during Waller's degeneration of peripheral nerves]. PMID- 4160579 TI - [Morphological substrate of the blood-brain barrier under physiologic and pathologic conditions]. PMID- 4160580 TI - [On the cellular storage of tellurium and its relationship to cytoplasmatic bodies summarized under the definition of lysosomes]. PMID- 4160581 TI - [Counter current principle of the kidney]. PMID- 4160582 TI - [Hermann Stahr May 30, 1868-Aug. 20, 1947]. PMID- 4160583 TI - [Helmut Baniecki July 31, 1899-Dec. 24, 1963]. PMID- 4160584 TI - [Gerhard Domagk Oct. 30, 1895-April 24, 1964]. PMID- 4160585 TI - [Walter Hans Schultze June 15, 1880-April 27, 1964]. PMID- 4160586 TI - [Julius Schorn Aug. 3, 1920-May 7, 1964]. PMID- 4160587 TI - [Erich Rix Sept. 29, 1900-Aug. 10, 1964]. PMID- 4160588 TI - [Heinrich Pette Nov. 23, 1887-Oct. 2, 1964]. PMID- 4160589 TI - [Nikolaj Nikolaevic Anickov Nov. 3, 1885-Dec. 7, 1964]. PMID- 4160590 TI - [Gerhard Sponholz April 14, 1896-Dec. 29, 1964]. PMID- 4160592 TI - [Physiopathology of acute renal failure]. PMID- 4160591 TI - [Johannes Dobberstein Sept. 19, 1895-Jan. 9, 1965]. PMID- 4160593 TI - [Pathological anatomy of acute kidney failure]. PMID- 4160594 TI - [Pathological anatomy of glomerulonephritis]. PMID- 4160595 TI - [Electron microscopic findings in glomerulonephritis]. PMID- 4160596 TI - [Bilateral chronic non-obstructive interstitial nephritides]. PMID- 4160597 TI - Histochemical studies of the hyperplastic prostate gland. PMID- 4160598 TI - [Carcinogenic aromatic hydrocarbons in the exhaust gases from automobile motors and methods for their detoxication]. PMID- 4160599 TI - Current aspects of the structure, function, and genetics of the immunoglobulins. PMID- 4160600 TI - Fragmentation of immunoglobulin during storage. PMID- 4160601 TI - The efficacy of fragmented immune serum globulin in passive immunization. PMID- 4160602 TI - [Our results with radiation therapy of inoperable bronchogenic carcinoma]. PMID- 4160604 TI - Goniophotometer to measure diffusion characteristics of rear projection screens. AMRL-TR-65-207. PMID- 4160603 TI - Some aspects of the use of cytostatic drugs in dermatology. PMID- 4160605 TI - [The problem of organized Botkin's disease control using gamma-globulin with special reference to the duration of induced immunity]. PMID- 4160606 TI - [Determination with the use of tissue cultures of the content of diphtherial antitoxin in gamma-globulins and immune sera]. PMID- 4160607 TI - [The biphasic effect of DDT and 666 on the biotransformation of pentobarbital in vivo]. PMID- 4160608 TI - Density gradient centrifugations of adenovirus-antibody comlexes. PMID- 4160609 TI - Some morphological characteristics of the internal component of measles virus. PMID- 4160610 TI - The dissociability of different poliovirus-antibody complexes as tested by hypertonic salt solutions. PMID- 4160611 TI - Cold stress and habenular lesion effects on rat behaviors. PMID- 4160612 TI - Immunohistochemical analysis of amyloid. PMID- 4160613 TI - Effect of resochin on the formation of the cells in vitro. PMID- 4160614 TI - Reversible inhibition of interferon synthesis by puromycin: evidence for an interferon-specific messenger RNA. PMID- 4160615 TI - [Study of hyperalphaglobulinemia. Study of 78 operated patients]. PMID- 4160616 TI - [Comparative studies on soluble proteins from tumor and normal tissues using agar and paper electrophoresis and fractional ammonium sulfate precipitation]. PMID- 4160617 TI - The histogenesis of Whipple's disease: a cytochemical, electron microscopic, and electron histochemical study. PMID- 4160618 TI - [The effect of antibiotics on components and partial reactions of the protein biosynthesis apparatus]. PMID- 4160619 TI - [Comparative studies on the nucleic acid synthesis in cell nuclei and mitochondria and their control by drugs]. PMID- 4160620 TI - [Inflammatory spontaneous perforation of a bladder cell]. PMID- 4160621 TI - [Serologic studies in children vaccinated against smallpox under protection of gamma globulin or methisazone]. PMID- 4160622 TI - [Traumatic cardiopathies in closed chest injuries]. PMID- 4160623 TI - [A review of corticotherapy]. PMID- 4160625 TI - [The diagnosis of pregnancy]. PMID- 4160624 TI - [Tetanus]. PMID- 4160626 TI - [Nurses in the school environment]. PMID- 4160627 TI - [Methods of vocational education in aged workers]. PMID- 4160628 TI - [Errors in the carrying out of drug prescriptions in the hospital environment]. PMID- 4160629 TI - [The benefit of epidemiological surveys on tuberculosis]. PMID- 4160630 TI - [The safety of hospitalized children and maternal-child welfare establishments]. PMID- 4160631 TI - [Admission to schools of nursing]. PMID- 4160632 TI - [Admission qualifications to midwifery schools]. PMID- 4160633 TI - [Effect of a thyreostatic drug on the blocking vessels of the rat thyroid gland]. PMID- 4160634 TI - [Indirect nematodifugic action exercised in the intestinal tract by a new imidazole derivative, introduced parenterally in the system of sheep]. PMID- 4160635 TI - Cytochemical studies in cell cultures infected with Rous sarcoma virus. PMID- 4160636 TI - Selective tracing of human gamma-M antibodies by the mixed haemadsorption technique using indicator red cells with an exterior coating of rabbit anti cynomolgus globulin. PMID- 4160637 TI - Nonspecific inhibition of PCA reaction in immunized guinea pigs. PMID- 4160638 TI - The relationship between skin-sensitizing antibodies and gamma-D globulin in the sera of ragweed-sensitive individuals. PMID- 4160639 TI - Immunoglobulin class and pattern of nuclear fluorescence in systemic lupus erythematosus. PMID- 4160640 TI - Ribonucleic acid and protein synthesis in Rhizophlyctis rosea zoospores. AB - LeJohn, Herbert B. (Purdue University, Lafayette, Ind.), and James S. Lovett. Ribonucleic acid and protein synthesis in Rhizophlyctis rosea zoospores. J. Bacteriol. 91:709-717. 1966.-The uniflagellate zoospores of Rhizophlyctis rosea display active motility and a high endogenous respiratory metabolism, but neither growth nor net ribonucleic acid (RNA) or protein synthesis can be measured by ordinary procedures. Nevertheless, synthesis can be detected with isotopic precursors. Uracil-C(14) is incorporated slowly into both the soluble and ribosomal RNA. Analysis of zoospore extracts (on diethylaminoethyl cellulose columns or sucrose gradients) after various periods of labeling suggested that most of the uracil incorporation represents slow synthesis of ribosomal precursor RNA and, ultimately, ribosomes. Actinomycin D caused an 80% inhibition of uracil incorporation. The most rapidly labeled RNA was susceptible to extensive degradation in cells treated with actinomycin, but the percentage of stable RNA increased with the time of incorporation before addition of the antibiotic. Neither the effects of actinomycin nor the results of chase experiments have established unequivocally the existence of turnover or the presence of a short lived "messenger" fraction in motile spores. Both leucine and methionine were slowly incorporated into a spectrum of cellular proteins. The methyl group of C(14)-methylmethionine also served as a methyl donor for the methylation of soluble RNA but not of ribosomal RNA. The observations that some of the newly synthesized RNA and protein occur in the intact 82S ribosomes and that actinomycin inhibits the low level of protein synthesis provide some indirect evidence for a very low rate of "messenger" synthesis and turnover in zoospores. PMID- 4160641 TI - The detection and localization of mineral fibers in tissue. PMID- 4160642 TI - Canine distemper virus in ferret, dog and bovine kidney cell cultures. PMID- 4160643 TI - Sleep patterns in the young adult female: an EEG study. PMID- 4160644 TI - The site of infection in pregnancy bacteriuria. PMID- 4160645 TI - The determination of glomerular filtration-rate in clinical practice. PMID- 4160646 TI - A comparison of the protective effect of methisazone and a hyperimmune antivaccinial gamma-globulin in primary smallpox vaccination carried out in the presence of contraindications. PMID- 4160647 TI - Carcinoma of the oesophagus with tylosis (keratosis palmaris et plantaris). PMID- 4160648 TI - Effect of pH on the incidence of infusion thrombophlebitis. PMID- 4160649 TI - Progression of retroperitoneal fibrosis despite cessation of treatment with methysergide. PMID- 4160650 TI - Correlation between sponge biopsies and uterine cervical smears. PMID- 4160651 TI - Methylprednisolone in the treatment of exophthalmos. PMID- 4160652 TI - The aetiology and pathogenesis of Burkitt's African lymphoma. PMID- 4160653 TI - Virus induction autoimmune disease and neoplasia. PMID- 4160654 TI - Voluntary sterilisation for family welfare. A proposal by the Simon population Trust. PMID- 4160655 TI - Another chance for thalidomide? PMID- 4160656 TI - Analysis of the urban atmosphere and air pollution source effluents for phenalen 1-one and 7 H-benz (de)anthracen-7-one. PMID- 4160657 TI - [The antibody content of normal and pathologic gamma globulin fractions of sera containing cryoglobulins with rheumatoid factor effect]. PMID- 4160658 TI - [Current evolutional problems of acute otitis in children]. PMID- 4160659 TI - [Possible effects of the taking of contraceptive products]. PMID- 4160660 TI - [Radiation effect under changed metabolic conditions]. PMID- 4160661 TI - [Jacob Erdheim May 22, 1874-April 21, 1937]. PMID- 4160662 TI - The study of calcification of mammalian cartilage in norm and pathology by stain historadiography. PMID- 4160663 TI - The representation of organisms in terms of predicates. PMID- 4160664 TI - [Anti-estrogenic and anti-androgenic effects of certain oral gestagens]. PMID- 4160665 TI - [Meaning and methods of gynecologic rehabilitation]. PMID- 4160666 TI - [On the description of the perineural localization of cervix carcinoma by means of inclusion stainings]. PMID- 4160667 TI - Brain mitochondria. IV. The activation of fatty acids in bovine brain mitochondria. PMID- 4160669 TI - Effects of thyrotropin upon thyroidal iodide; studies using thyroid venous cannulation and two radioiodine isotopes. PMID- 4160668 TI - Albumin metabolism in patients with Whipple's disease. PMID- 4160670 TI - The proteins in nasal secretion: a longitudinal study of the gammaA-globulin, gammaG-globulin, albumin, siderophilin, and total protein concentrations in nasal washings from adult male volunteers. PMID- 4160671 TI - [Malignant melanoma in children]. PMID- 4160672 TI - [On increased iodine uptake by the thyroid gland without hyperfunction]. PMID- 4160673 TI - [Value and limitations of thyroid gland diagnosis with radioiodine]. PMID- 4160674 TI - [New aspects in the therapy of hyperthyroidism from the view of the specialist for internal medicine]. PMID- 4160675 TI - Video tape recording of tracheobronchial dynamics. PMID- 4160676 TI - Susceptibility of mycobacteria to 4,4'-diisoamyloxythiocarbanilide. PMID- 4160677 TI - Effect of actinomycin C on glucose-6-phosphate dehydrogenase activity of a human adenocarcinoma growing in a heterologous host. PMID- 4160678 TI - Immunoglobulin responses to bacterial endocarditis. PMID- 4160679 TI - Studies of ACTH antibodies and their reactions with inactive analogues of ACTH. PMID- 4160680 TI - Concerning the staining properties of aldehyde basic fuchsin. PMID- 4160681 TI - Hyaline bodies in carbon tetrachloride-damaged hepatic cells: nucleosidediphosphatase activity. PMID- 4160682 TI - Esterases and proteins of normal and atrophic feline muscle. PMID- 4160683 TI - A simple method for the determination of water content and protein concentration in subcellular elements. PMID- 4160684 TI - Normal human neutrophil leukocytes as a reference system for the microspectrophotometrically quantitated periodic acid-Schiff reaction. PMID- 4160685 TI - Selective localization of nucleolar protein with amido black 10B. PMID- 4160686 TI - Accurate identification of experimental pulmonary metastases. PMID- 4160687 TI - [Treatment of whooping cough complications in 1963]. PMID- 4160688 TI - A new immunological test for monoclonal macroglobulinemia--a preliminary report. PMID- 4160689 TI - A genetic predisposition to Waldenstrom's macroglobulinaemia. PMID- 4160690 TI - [Heterogeneity of myeloma proteins]. PMID- 4160691 TI - Coagulation studies in different types of myeloma. PMID- 4160692 TI - [On the occurrence of basophilic corpuscles on the erythrocytes in the blood following splenectomy]. PMID- 4160693 TI - Waldenstrom's chronic active hepatitis. PMID- 4160694 TI - Current trends in immune globulin research. PMID- 4160695 TI - Structural relationship between gamma-G- and gamma-M-globulin in man. PMID- 4160696 TI - Biological significance of exocrine gamma-A-immunoglobulin. PMID- 4160697 TI - Sedimentation constants of IgG and IgD myeloma proteins compared with those of normal IgG. PMID- 4160698 TI - The frequency of pronounced polyclonal hypergammaglobulinaemia in a random population. PMID- 4160699 TI - Action of epsilon-aminocaproic acid and of parotid inhibitor on the fibrinolysis activation due to nicotinic acid derivatives and to heparin-like substances. PMID- 4160700 TI - Studies on chemotaxis. 3. Modification of Boyden's technique for the evaluation of chemotactic agents. PMID- 4160701 TI - The properties of isolated serum and urinary antibodies to a single antigen. PMID- 4160702 TI - Production of antibody against purified human gamma-G-globulin in rabbits, goats, sheep and horses. A report to the Medical Research Council by a sub-committee of their blood transfusion research committee. PMID- 4160703 TI - [Report on experiences with Lasonil]. PMID- 4160704 TI - [Experiences with compression bandage therapy in venous inflammations]. PMID- 4160705 TI - Antibody response in the rat. II. Microclasmatosis, a possible mode of antibody release. PMID- 4160706 TI - Identification of rat urinary proteins by zone and immunoelectrophoresis. PMID- 4160708 TI - The physiologic basis and clinical implications of paired pulse stimulation of the heart. PMID- 4160707 TI - Air pollution and health. PMID- 4160709 TI - The synthesis of thyromimetic substances and potential inhibitors of thyroxine. PMID- 4160710 TI - Significance of dysmenorrhea in infertility. Report of a preliminary study of therapy with a sequential estrogen-progestagen regimen. PMID- 4160711 TI - The cytologic diagnosis of ovulatory function. PMID- 4160712 TI - [Apropos of the effect of changed condition of the nervous system on the incidence of protein sensitization]. PMID- 4160713 TI - [An improved method for the determination of the circulating blood volume using albumin labeled with I-131]. PMID- 4160714 TI - Experimental Coxsackie virus B4 valvulitis in cynomolgus monkeys. PMID- 4160715 TI - [On the possibility of identifying LH-ICSH cells in the dog adenohypophysis with lead hematoxyline]. PMID- 4160716 TI - Creation of an atrial septal defect without thoracotomy. A palliative approach to complete transposition of the great arteries. PMID- 4160717 TI - The oxidase activity of serum ceruloplasmin in multiple sclerosis. PMID- 4160718 TI - Roentgen irradiation effects on mouse proteins. PMID- 4160719 TI - The evaluation of a nasal decongestant preparation. PMID- 4160720 TI - [Variations of the Gomori-Grocott and periodic acid-Schiff technics for staining of the wall and internal structure of some varieties of fungi]. PMID- 4160721 TI - [Some immunological problems in the newborn]. PMID- 4160722 TI - [The sulfide framework and conformation of gamma-globulin]. PMID- 4160723 TI - [Nomenclature of human immune globulins]. PMID- 4160724 TI - Intraoral North American blastomycosis. PMID- 4160725 TI - Mucopolysaccharide keratin dystrophy of the oral epithelium. PMID- 4160726 TI - A genetic approach to the pathogenesis of hepatic cirrhosis. A clinical and serological study. PMID- 4160727 TI - On the viability of tumour cells in artificially produced suspensions. PMID- 4160728 TI - Specificity of anti-antibodies in human sera. PMID- 4160729 TI - Quantitative determinations of incomplete anti-D antibodies in reaction with anti Gm factors. PMID- 4160730 TI - Studies on non-specific antistreptolysin O titre. 2. Comparison of specific and non-specific antistreptolysins by gelfiltration and dextran sulphate precipitation. PMID- 4160731 TI - Elevation of the serum protein-bound iodine level in inhabitants of the Marshall Islands. PMID- 4160732 TI - Factors affecting the determination of the serum protein-bound iodine. PMID- 4160733 TI - Carcinoma of the esophagus. A twenty year study. PMID- 4160734 TI - Necrosis of the breast: a rare complication of anticoagulant therapy. PMID- 4160735 TI - Steroid-protein interactions. XI. Electrophoretic characterization of corticosteroid-binding proteins in serum of rat, man and other species. PMID- 4160736 TI - Aggregation of chicken gamma-G immunoglobulin in 1.5 M sodium chloride solution. PMID- 4160737 TI - Differential staining of viable and nonviable spermatozoa with fluorescence microscopy. PMID- 4160738 TI - A cold agglutinin of the IgA class. PMID- 4160739 TI - The effect of hydrostatic pressure on the rate of inactivation of Cypridina luciferase by specific antibody. PMID- 4160740 TI - Antigenic determinants of human beta-1c and beta-1g-globulins. PMID- 4160741 TI - Catabolism of gammaG-globulin with reduced interchain disulfide bonds in rabbits. PMID- 4160742 TI - Autoimmune hepatitis. Immunofluorescence reactions with cytoplasm of smooth muscle and renal glomerular cells. PMID- 4160743 TI - Serum-insulin in essential hypertension and in peripheral vascular disease. PMID- 4160744 TI - A possible hereditary factor in the nasal carriage of staphylococci. PMID- 4160745 TI - High serum-folate levels in intestinal blind-loop syndrome. PMID- 4160746 TI - Hunger during total starvation. PMID- 4160747 TI - Excretion of pregnanetriol in a case of hydatidiform mole associated with ovarian theca lutein cysts. PMID- 4160748 TI - Splenomegaly and sickle-cell trait in a malaria-endemic village. PMID- 4160749 TI - Effect of hyperbaric oxygen on the growth of aerobic organisms in deep culture. PMID- 4160750 TI - Leucocyte-vitamin-C content and clinical signs in the elderly. PMID- 4160751 TI - Renal carcinoma with myopathy-like features. PMID- 4160752 TI - Inactivation of chlorhexidine ("hibitane") by bark corks. PMID- 4160753 TI - Improved thigh sphygmomanometer cuff. PMID- 4160754 TI - A suction amniotomy instrument for surgical induction of labor. PMID- 4160755 TI - Osteoarthrosis. PMID- 4160756 TI - Radiosensitisers. PMID- 4160757 TI - Outpatient services. PMID- 4160758 TI - Natural regressions in malignant tumours. PMID- 4160759 TI - Coordination in the care of the elderly. PMID- 4160760 TI - The National Health Service. Reflections by an American family doctor. PMID- 4160761 TI - Bacterial aerosol from water closets. A comparison of two types of pan and two types of cover. PMID- 4160762 TI - [Sequential clinical analysis of a new product with an antirhinitis action]. PMID- 4160763 TI - Newer knowledge of ovine vibriosis. PMID- 4160764 TI - Clinical management of neonatal diarrhea in calves, with special reference to pathogenesis and diagnosis. PMID- 4160765 TI - [Porphyrins and the diagnostic significance of their determination (review of the literature)]. PMID- 4160766 TI - [Errors in the measurement of some indices of lesser circulation hemodynamics and of the function of the respiratory apparatus]. PMID- 4160767 TI - [Nitrogen determination in biological substances by means of Berthelot's reaction]. PMID- 4160768 TI - [Methods of accelerated dialysis and concentration of protein solutions by means of ultrafiltration in a vacuum]. PMID- 4160769 TI - [Standard solution for cholesterol determination]. PMID- 4160770 TI - [Determination by the same method of total blood serum proteins, blood plasma fibrinogen and gastric juice pepsin]. PMID- 4160771 TI - [Spectrophotometric method of pH determination of nutritional media for tissue cultures]. PMID- 4160772 TI - [Methods of zonal or specimen paper electrophoresis of hemoglobin]. PMID- 4160773 TI - [An accelerated method of determination of fibrinase activity]. PMID- 4160774 TI - [Method of thrombelastography using citrated plasma]. PMID- 4160775 TI - [Erythrocyte diagnosticum for the development of Vi-antibodies in serums]. PMID- 4160776 TI - [A method of obtaining standard immune serums against tick-borne encephalitis]. PMID- 4160777 TI - [A method of determination of the immunological properties of serum proteins]. PMID- 4160779 TI - [On impregnation by silver of toxoplasma cysts]. PMID- 4160778 TI - [Rapid determination of bacterial sensitivity to antibiotics]. PMID- 4160781 TI - [Portable device for the determination of the microorganism content of soft articles]. PMID- 4160780 TI - [Evaluation of the action of merthiolate and formalin on some cell cultures]. PMID- 4160782 TI - [The post-traumatic Sudeck syndrome. Radiographic pictures]. PMID- 4160783 TI - Sodium diuresis after relief of obstructive uropathy. PMID- 4160784 TI - [The cases of shoulder-hand syndrome treated satisfactorily with griseofulvin]. PMID- 4160785 TI - The role of the sympathetics in premature systoles. PMID- 4160786 TI - Vitally stained kappa in Paramecium aurelia. PMID- 4160787 TI - Monoclonal and diclonal gamma-pathies. PMID- 4160788 TI - Fluorescein studies in fundus flavimaculatus and drusen. PMID- 4160789 TI - Transsphenoidal hypophysectomy for diabetic retinopathy. Preliminary study of 18 cases. PMID- 4160790 TI - [Remarks on the problem of indications for use and the so-called detoxication of streptomycin (dihydrostreptomycin)]. PMID- 4160791 TI - [Treatment of bacterial infections with combined preparations of streptomycin or dihydrostreptomycin and penicillin]. PMID- 4160793 TI - Bronchogenic carcinoma, stages 3 and 4. Palliation by radiotherapy. PMID- 4160792 TI - Bronchogenic carcinoma, stages 3 and 4. Palliation by chemotherapy. PMID- 4160794 TI - Bronchogenic carcinoma, stages 3 and 4. Palliation by surgery. PMID- 4160795 TI - [Immunological studies on the influence of cysteine hydrochloride on anti-I agglutinins]. PMID- 4160796 TI - Tetanus. Its prophylaxis and treatment. PMID- 4160797 TI - The immunofluorescent tumor imprint technique. II. The frequency of antinuclear factors in connective tissue diseases and dermatoses. PMID- 4160798 TI - Management of thyroid problems in the geriatric patient. PMID- 4160799 TI - Keratin in normal and abnormal epidermis. PMID- 4160800 TI - [Hereditary alpha-1 antitrypsin deficiency; its relation to chronic obstructive bronchopulmonary diseases]. PMID- 4160801 TI - [Immunoelectrophoretic studies of serum proteins in children with measles with special reference to immune globulins]. PMID- 4160802 TI - [Studies on the epiphysis cerebri and the subcommissural organ of the frog. With live observation of the epiphysial circulation, complete staining of the subcommissural organ and severing of Reissner's fiber]. PMID- 4160803 TI - Palliation and life prolongation with anticancer drugs. PMID- 4160804 TI - On the significance of the heterogeneity in molecular size of human serum gamma A globulins. PMID- 4160805 TI - The concept of the centron. PMID- 4160806 TI - [Microspectrophotometric investigations with the UMSP I (C.Zeiss) on the outer epidermis of the scaly leaves of Allium cepa after staining with neutral red]. PMID- 4160807 TI - Nonthrombogenic plastic surfaces. AB - Heparin has been chemically combined with a number of plastic surfaces rendering them nonthrombogenic as judged by Lee-White coagulation tests in vitro with human blood. Addition of quaternary ammonium groups to the plastic permitted formation of insoluble complexes with heparin. These heparinized surfaces were essentially nonthrombogenic and adsorb blood proteins to a significantly smaller degree from dilute solution than do the unmodified plastic surfaces. The affinity of the formed blood elements for these modified surfaces is much less than for the unmodified surfaces. PMID- 4160808 TI - Electrophoretic heterogeneity of the polypeptide chains of human G-myeloma proteins. AB - The light and heavy polypeptide chains derived from human Gmyeloma proteins are electrophoretically heterogeneous as judged by disc electrophoresis of the polypeptide chains in urea-acrylamide gels. Individual myeloma proteins contained as many as eight light-chain and nine heavy-chain components. PMID- 4160809 TI - Tritiated norepinephrine: release from brain slices by electrical stimulation. AB - Slices of rat brain and heart that had concentrated H(3)-norepinephrine were superfused and electrically stimulated. Stimulation induced a marked release of H(3)-norepinephrine with a threshold and a maximum repsonse. Release also occurred with increased concentrations of potassium, presumably due to neuronal depolarization. Inhibition of electrically induced release occurred with low calcium and with chlorpromazine and pentobarbital. PMID- 4160810 TI - Staining tissue for light and electron microscopy by bridging metals with multidentate ligands. AB - "Osmium black," a pigment very useful for cytological staining in both light and electron microscopy, may be deposited selectively at the tissue-binding sites of other metal ions by bridging OsO(4) to the tissue bound metal ion through a multidentate ligand. PMID- 4160811 TI - Isoniazid with thiacetazone (thioacetazone) in the treatment of pulmonary tuberculosis in East Africa--third investigation: the effect of an initial streptomycin supplement. PMID- 4160812 TI - An international co-operative investigation into thiacetazone (thioacetazone) side-effects. PMID- 4160813 TI - Adult hypoglycaemia associated with neoplasia. A report of three cases with a note on the use of diazoxide. PMID- 4160814 TI - Prostatic obstruction in the African and Asiatic. PMID- 4160815 TI - Some side effects of heparin, heparinoids, and their antagonists. PMID- 4160816 TI - The nephrotic syndrome of childhood: immunologic, clinical, and pathologic correlations. PMID- 4160817 TI - Rabbit lymphoid cells differentiated with respect to alpha-, gamma-, and mu- heavy polypeptide chains and to allotypic markers Aa1 and Aa2. AB - Lymphoid cells present in spleen and lymph nodes of hyperimmune rabbits were found to be differentiated with respect to the class of immunoglobulin heavy chain which they contained. The relative proportions of cells containing the various heavy chains were as follows: alpha-chain (5 to 8%), micro-chain (14 to 21%), and gamma-chain (71 to 81%). The allotypic markers Aa1 and Aa2, found on heavy chains, were also found to be separately localized in cells of Aa(1)/Aa(2) heterozygous rabbits. The ratio of cells in spleen and lymph nodes containing the Aa1 marker to those containing the Aa2 marker varied with individual rabbits; the range was 53 to 88% Aa1 versus 12 to 47% Aa2. PMID- 4160818 TI - [On the gamma-globulin system (including multiple myeloma)]. PMID- 4160819 TI - Electrophoretic heterogeneity of polypeptide chains of specific antibodies. AB - Heavy and light polypeptide chains isolated from different specific antibodies to haptens and from (gamma)G-immunoglobulin of normal rabbits have been resolved into distinct, multiple components by disc electrophoresis in polyacrylamide gels in the presence of urea. In spite of the resolution of these chains into multiple bands, different specific antibodies and normal rabbit (gamma)G-immunoglobulin were indistinguishable from each other by this method. PMID- 4160820 TI - Effect of interferon on early interferon production. AB - Chick embryo cells given prior treatment with interferon make new interferon earlier and in larger quantities upon stimulation with Chikungunya virus than cells not so treated. By the criterion of loss of sensitivity to actinomycin, the time needed for formation of messenger RNA for interferon was decreased in the primed cells. Thus interferon affects virus action within 1 hour after infection. PMID- 4160821 TI - Lymphoid cells producing antibody against simple haptens: detection and enumeration. AB - Enumeration of cells producing antibody against arsanilic acid was made feasible by the use of hapten-conjugated sheep erythrocytes for the localized hemolysis-in gel technique. The time of appearance and numbers of these hapten-specific plaque forming cells correlated closely with the development of arsanilic acid-specific serum antibodies. PMID- 4160822 TI - The relationship of thyroid disease and the atopic state. PMID- 4160823 TI - Prosthetic treatment for palatopharyngeal incompetence: research and clinical implications. PMID- 4160824 TI - Growth, morphogenesis, and virulence of Candida albicans after oral inoculation in the germ-free and conventional chick. AB - Balish, Edward (Syracuse University, Syracuse, N.Y.), and A. W. Phillips. Growth, morphogenesis, and virulence of Candida albicans after oral inoculation in the germ-free and conventional chick. J. Bacteriol. 91:1736-1743. 1966.-The effects of intestinal bacteria on the multiplication, morphogenesis, and infectivity of Candida albicans in the alimentary tract were investigated by comparing results obtained in germ-free and conventional chicks after oral inoculation. This challenge resulted in the establishment of large numbers of the pathogen in the alimentary tract of each group of chicks; these numbers were increased in crop contents from challenged bacteria-free chicks wherein hyphae predominated over the yeast form. These animals also had lesions of the crop epithelium containing numerous hyphae and few yeast-like forms. In contrast, challenged conventional chicks receiving an adequate diet displayed no evidence of infection. Their alimentary tract contained the yeast form of C. albicans; no hyphae were seen. Although we found bacterial inhibition of C. albicans multiplication in the alimentary tract, this in itself did not seem to explain the resistance to intestinal candidiasis in our conventional chicks. We argued that this resistance to infection was due chiefly to the prevention of hyphal development in C. albicans by intestinal bacteria. C. albicans in the gut of our conventional chicks resulted in some increase in numbers of enterococci in contents from the crop. Increased pH values in contents from the gut of germ-free chicks were not clearly related to infection after challenge. The E(h) of the above crop contents were only slightly decreased in the germ-free crop. Thus the E(h) did not appear to be involved in susceptibility to infection. Invasion of the blood stream and kidneys of conventional chicks by the yeast form of C. albicans occurred in challenged animals receiving a purified diet which had been radiation-sterilized and stored for 6 months at room temperature (25 C). Their growth rate decreased and they became moribund; no hyphae were observed in tissues or intestine of these animals. Challenged bacteria-free chicks receiving the same diet were resistant to the above invasion, although they had crop lesions containing hyphae as described. The resistance of these chicks to systemic invasion was attributed to absence of intestinal bacteria competing for low levels of vitamins in the stored diet. Germ-free chicks had decreased levels of serum gamma-globulin which increased after challenge, whereas this value was unchanged in conventional birds after challenge. PMID- 4160825 TI - Growth and virulence of Candida albicans after oral inoculation in the chick with a monoflora of either Escherichia coli or Streptococcus faecalis. AB - Balish, Edward (Syracuse University, Syracuse, N.Y.), and A. W. Phillips. Growth and virulence of Candida albicans after oral inoculation in the chick with a monoflora of either Escherichia coli or Streptococcus faecalis. J. Bacteriol. 91:1744-1749. 1966.-Bacterial protection against intestinal infection by Candida albicans was investigated in chicks with a monoflora of either Escherichia coli or Streptococcus faecalis. These animals were obtained by orally inoculating germ free chicks (3 days old) with pure cultures of bacteria. Each bacterial species was established in large numbers in the gut of separate groups of animals within 24 hr of inoculation; these numbers were similar in chicks examined 34 days later, at which time all animals were killed. The numbers of bacteria from contents of the crop, small intestine, and ceca were similar in chicks with the E. coli monoflora. Comparable results were obtained in chicks with the S. faecalis monoflora, except for decreased numbers in the duodenum and jejunum. Some of the monoflora chicks (7 days old) were transferred into separate isolators, orally inoculated with C. albicans, and observed for 34 days. All chicks grew well and appeared healthy. However, examinations at autopsy revealed severe crop infections in chicks with a diflora containing S. faecalis. Preferential growth of hyphae (C. albicans) occurred in the lesions and throughout the gut. The numbers of S. faecalis in the gut were comparable to those found in unchallenged animals. Agglutinins against C. albicans were not detected in our test or control chicks. Chicks with a diflora containing E. coli and C. albicans had a few microscopic crop lesions containing small numbers of hyphae. C. albicans was well established in the gut of these animals, largely as the yeast form. The numbers of E. coli in the gut were similar to those in control chicks. Thus, it was concluded that E. coli provided protection against crop infection by C. albicans. In crop contents from unchallenged animals, chicks with S. faecalis monoflora were about pH 5, whereas birds with E. coli monoflora were about pH 7. The challenge did not greatly change the former value, and the latter was slightly decreased. In the crop of unchallenged birds, negative E(h) values were found in chicks with S. faecalis and positive E(h) values in those with E. coli. Challenge did not greatly change these values. These data on pH and E(h) were related to conditions for morphogenesis of C. albicans and virulence. No major difference in the concentrations of serum proteins was seen in chicks with E. coli or S. faecalis after challenge with C. albicans. Possible mechanisms of the protective effect of E. coli are discussed. PMID- 4160826 TI - Technique for visualizing papovaviruses in tumors and in tissue cultures. PMID- 4160827 TI - Filamentous and tubular structures in mammalian axoplasm. An electron microscopic study. PMID- 4160828 TI - Rubro-cerebellar connections in the cat: an experimental study with silver impregnation methods. PMID- 4160829 TI - [Significance of the determination of free oxygen in tissues in some hygienic investigations]. PMID- 4160830 TI - [Study of the dynamics of serum antibodies in organ and tissue homotransplantation]. PMID- 4160831 TI - [Short outline of immunoglobulin knowledge and of immunological processes]. PMID- 4160832 TI - [Effect of the adjuvant on the process of antibody formation (immuno-fluorescent studies)]. PMID- 4160833 TI - [Effect of passive immunization on the sensitizing effect of Bordetella pertussis. 3. Development of increased sensitivity to histamine]. PMID- 4160834 TI - 6-alpha-methyl- 17-alpha-hydroxyprogesterone acetate as a chemotherapeutic agent in adenocarcinoma of the uterus. PMID- 4160835 TI - Antibody synthesis in poikilothermic vertebrates. PMID- 4160836 TI - The accumulation of synthetic chelating agents in osseous tissues. PMID- 4160837 TI - Further studies of the mechanism of passive sensitization. AB - 1. The mechanism of passive sensitization of chopped guinea-pig lung when incubated with rabbit antiserum alone and in the presence of non-antibody gamma globulin has been investigated.2. The effect of concentrations of antibody on the fraction of receptors occupied by molecules attached at one, two or three points has been calculated assuming mass action relations. If a single attachment is sufficient for sensitization the predicted log concentration-effect curve is S shaped; if two or more attachments are needed the curve is bell-shaped. The effect of inhibiting non-antibody gamma-globulin on the shape and position of the curves has also been calculated.3. The effect of incubating with a wide range of concentrations of antibody on the subsequent histamine release with antigen has been determined. Bell-shaped curves were obtained. Their shape and position were altered by inhibiting non-antibody in a manner predicted by the two-point attachment hypothesis.4. The first affinity constants for antibody and non antibody gamma-globulin have been calculated from the experimental concentration effect curves. They are similar and have a value of about 10(7) l./mole. Approximate values for the second affinity constants and for the fraction of receptors effectively occupied at maximum sensitization have also been estimated. PMID- 4160839 TI - Functional and metabolic effects of total and selective vagotomy. PMID- 4160838 TI - Complications of diuretic therapy in hepatic cirrhosis. PMID- 4160840 TI - Countercurrent exchange between the vasa recta and the loop of Henle. PMID- 4160841 TI - Gastrointestinal protein loss measured with 59Fe-labelled iron-dextran. PMID- 4160842 TI - Plasma thiocyanate and vitamin B12 in Nigerian patients with degenerative neurological disease. PMID- 4160843 TI - Chronic portal-systemic encephalopathy after ileostomy and colonic resection. PMID- 4160844 TI - Cholera in children. PMID- 4160845 TI - An isothiazole thiosemicarbazone in the treatment of variola major in man. A controlled clinical trial and laboratory investigations. PMID- 4160846 TI - Assessment of an isothiazole thiosemicarbazone in the prophylaxis of contacts of variola major. PMID- 4160847 TI - Combined action of methyldopa and bethanidine. Evidence for a synergistic effect. PMID- 4160848 TI - Administration of measles vaccine by dermojet. PMID- 4160849 TI - Infusion of dextrose solution in cardiogenic shock. PMID- 4160850 TI - Bladder retractor. PMID- 4160851 TI - Trace elements. PMID- 4160852 TI - Coronary angiography. PMID- 4160853 TI - Voluntary workers in a psychiatric hospital. PMID- 4160854 TI - Suxamethonium and uterine activity. PMID- 4160855 TI - Tetracyclines and the teeth. PMID- 4160856 TI - Postoperative infection with Pseudomonas aeruginosa in an eye hospital. PMID- 4160857 TI - Radioimmunoassay for human chorionic gonadotrophin and luteinising hormone. PMID- 4160858 TI - Cathartic colon. PMID- 4160859 TI - Effects of dextran 40 on erythrocyte aggregation. PMID- 4160860 TI - Pulmonary aspiration of gastric contents in obstetric patients. A report of two patients treated by artificial ventilation. PMID- 4160861 TI - Apparent cri-du-chat and "antimongolism" in one patient. PMID- 4160862 TI - Minor ocular abnormalities associated with thalidomide. PMID- 4160863 TI - Effect of thalidomide on the immunological response in local lymph nodes after a skin homograft. PMID- 4160864 TI - Immunosuppression by thalidomide: implications for teratology. PMID- 4160865 TI - Apparatus for turning patients. PMID- 4160867 TI - Breathlessness. PMID- 4160866 TI - Pseudomonas aeruginosa. PMID- 4160868 TI - Living records. PMID- 4160869 TI - Suxamethonium and uterine activity. PMID- 4160870 TI - Turner's Syndrome and phenotype. PMID- 4160871 TI - The Christchurch chromosome. PMID- 4160872 TI - Chromosomes in cleft-palate tissues. PMID- 4160873 TI - Methyldopa and haemolytic anaemia. PMID- 4160874 TI - Dehydroemetine in chronic leukaemia. PMID- 4160875 TI - Cyclophosphamide treatment of kidney disease in (NZB x NZW) F1 mice. PMID- 4160876 TI - Observations on the mechanisms of infarction in the dog after experimental occlusion of the coronary artery. PMID- 4160877 TI - Gastric secretory patterns before and after vagotomy. PMID- 4160878 TI - T-strain mycoplasma in non-gonococcal urethritis. PMID- 4160879 TI - Generalised vaccinia in the human foetus. PMID- 4160880 TI - Increased dispersal of skin bacteria into the air after shower baths: the effect of hexachlorophene. PMID- 4160881 TI - Arginine infusion in maturity-onset diabetes mellitus. Defective output of insulin and of growth hormone. PMID- 4160882 TI - Relationship between postoperative changes in adenosine-diphosphate induced platelet adhesiveness and venous thrombosis. PMID- 4160883 TI - The vascular fault in chronic hypertension with particular reference to the role of medial hypertrophy. PMID- 4160884 TI - Diarrhoea and acid-base disturbances. PMID- 4160885 TI - Lead absorption and lead poisoning. PMID- 4160886 TI - Adrenergic receptors. PMID- 4160888 TI - Follow-ups of elderly discharged patients. PMID- 4160887 TI - Variola minor. A preliminary report from the Birmingham Hospital region. PMID- 4160889 TI - Not to be left to nature. PMID- 4160890 TI - [Histologic observations and mucopolysaccharide distribution in monostotic fibrous dysplasia with mandibular localization (Jaffe-Lichtenstein disease)]. PMID- 4160891 TI - Plaque localization and distribution of vasa vasorum. A micro-angiological study of the human abdominal aorta. PMID- 4160892 TI - Ribonucleic acid content of Burkitt tumour cells. AB - Methyl-green-pyronin-Y staining was performed on 57 biopsies of Burkitt's tumour and 62 biopsies from other types of malignant lymphoma. The specificity of the pyronin staining for ribonucleic acid (RNA) was controlled by staining duplicate slides previously digested in ribonuclease. Burkitt's tumour cells have a higher cytoplasmic content of RNA than the cells of most other malignant lymphomas. The results of acridine orange staining of a smaller number of biopsies support these findings. PMID- 4160893 TI - Granulocyte changes in infectious mononucleosis. AB - Various changes in the granulocytes have been investigated in a large series of patients with infectious mononucleosis. A high proportion of cases regularly show a neutropenia with a shift to the left during the first three to four weeks of the disease; these changes, though transient, may be profound. The band cells present during the acute phase of the disease also show certain alterations in cytochemical staining and low alkaline phosphatase scores are common at this time. The maturation and release of leucocytes from the bone marrow is apparently normal. Theoretical mechanisms for the neutropenia are briefly discussed, including the possible role of excessive peripheral destruction. PMID- 4160894 TI - Simultaneous demonstration of mast cells and plasma cells. PMID- 4160895 TI - Structural changes in the incisors of cortisone-treated rats. PMID- 4160896 TI - Vascular and nerve supply to the molar teeth of guinea pigs. PMID- 4160897 TI - Oxytalan fibers in the periodontium of ascorbic acid-deficient guinea pigs. PMID- 4160898 TI - Biomechanical control of bone growth and development: a histologic and tetracycline study. PMID- 4160899 TI - [Reactions of a myelomatous type in the course of collagen diseases]. PMID- 4160900 TI - Absence of alpha globulin from the egg white of the domestic turkey. PMID- 4160901 TI - Oxygen consumption and NADPH oxidation in microsomes from vitamin K-deficient, warfarin- and dicumarol-treated rats. PMID- 4160902 TI - [Dysproteinemia of myeloma]. PMID- 4160904 TI - Pathogenesis of hyaline formation in sarcoidotic lymph nodes. PMID- 4160903 TI - [Antitetanus prophylaxis with specific human gamma globulins]. PMID- 4160905 TI - Serum proteins and glucoproteins in sarcoidosis. PMID- 4160906 TI - Serum proteins in sarcoidosis. PMID- 4160907 TI - Whipple's disease: evolution of current concepts. PMID- 4160908 TI - A primary isolation medium. For the differentiation of genus Proteus from other non-lactose and lactose fermenters. PMID- 4160909 TI - Primary biliary cirrhosis-positive antibody tests associated with increased immunoglobulin. PMID- 4160910 TI - Whipple's disease with clinical remission induced by ampicillin. PMID- 4160911 TI - [Derivative of 4,9-dihydrothieno(2,3-b)benzo(e)thiepine--a new type of effective antihistaminic]. PMID- 4160912 TI - Thyroid function and glaucoma. PMID- 4160913 TI - Congenital indifference to pain. PMID- 4160914 TI - The effects of chemical modifications of human gamma-globulins on their interaction with rheumatoid factors and antibodies. PMID- 4160915 TI - [Dysuria caused by pressure of osteochondroma]. PMID- 4160916 TI - Studies on nucleic acid metachromasy. I. The effect of certain fixatives on the dye stacking properties of nucleic acids in solution. AB - The stacking coefficients (K's) of nucleic acids have been thought to influence the color contrast between DNA and RNA in tissue sections stained with metachromatic dyes. This idea was tested by titrating toluidine blue (TB) and acridine orange (AO) in solution against DNA and RNA, native or treated with formaldehyde, acrolein, or Carnoy's fluid. Absorption spectra at varying polymer dye ratios were used to compute K values by the methods of Bradley and colleagues. Results with both dyes fit Bradley's stacking equations. Fixatives did not block dye-binding sites but markedly altered K values. K of DNA was low, unaffected by aldehyde fixative, increased by Carnoy's fluid or heat denaturation. K of RNA was higher than that of DNA and was increased greatly by formaldehyde, almost as much by acrolein, considerably less by Carnoy's fluid. Aldehyde effects were partially reversed upon removal of aldehyde by dialysis. These observations accord with known effects of aldehydes and denaturation upon nucleic acid conformation. Differences between K's of DNA and RNA were greater after aldehyde treatment than after Carnoy's, and were greater with AO than with TB. This is generally consistent with the magnitude of the color contrasts observed in tissues. Additional factors must contribute to the intense color contrast observed in acrolein-fixed tissues stained with TB. PMID- 4160917 TI - Studies on nucleic acid metachromasy. II. Metachromatic and orthochromatic staining by toluidine blue of nucleic acids in tissue sections. AB - Acrolein-fixed, polyester wax-embedded tissue sections showed excellent preservation of light microscopic architecture and, when stained with toluidine blue, intense color contrast between DNA, which stained orthochromatically, and RNA, which stained metachromatically. This method has practical value for differentiating DNA from RNA in the same section. The color contrast was impaired by substituting formaldehyde for acrolein or paraffin for polyester wax, and was negligible in tissues fixed in formaldehyde or Carnoy's fluid and embedded in paraffin. Quality of structural preservation paralleled degree of color contrast. Metachromatic staining can be analysed, by the quantitative parameters of Bradley and colleagues, to provide inferences regarding the conformation of biopolymers in tissue sections. Comparison of the nucleic acid color contrasts in toluidine blue-stained sections with titrations of fixative-treated nucleic acids against toluidine blue in solution indicated a greater difference in conformation between DNA- and RNA-protein in acrolein-polyester sections than between acrolein-treated free DNA and RNA in solution. This is supported by recent evidence that the conformation of ribosomal RNA is quite different in whole ribosomes from that assumed by the same RNA free in solution. The acrolein-polyester method may enhance color contrast by providing superior preservation of ordered nucleoprotein conformations. PMID- 4160918 TI - Serum protein changes associated with Oesophagostomum columbianum infections in sheep. PMID- 4160919 TI - [Antigenicity of nucleic acids]. PMID- 4160920 TI - [Colposcopic diagnosis of gynecological trichomoniasis]. PMID- 4160921 TI - [Mediofacial malignant granuloma in a 4-month-old child]. PMID- 4160922 TI - [The role of the nurse in the urological care of paraplegics]. PMID- 4160924 TI - [Hyperbaric oxygen therapy]. PMID- 4160923 TI - [The current state of the hemophilia problem]. PMID- 4160925 TI - [Indications for cesarean section]. PMID- 4160926 TI - [Observation of the patient: nephrotic syndrome]. PMID- 4160928 TI - [Case study of a diabetic]. PMID- 4160927 TI - [Home care services of the French Red Cross in a rural area]. PMID- 4160929 TI - [Hospitalization at home within the limits of the anticancer centers of the Paris area]. PMID- 4160930 TI - [A survey on faulty diet in the Paris area]. PMID- 4160931 TI - [The demographic situation in France]. PMID- 4160932 TI - [The WHO and health protection for students]. PMID- 4160933 TI - [Respiratory function test]. PMID- 4160934 TI - Studies on purified C'1 esterase and hereditary angioneurotic oedema sera by combined electrophoresis and immune haemolysis. PMID- 4160935 TI - The mannequin. A teaching aid in ophthalmology. PMID- 4160936 TI - [Localization of antistreptokinase in the range of immunoproteins]. PMID- 4160937 TI - Inhibition by heparinoid of aldosterone biosynthesis in man. PMID- 4160938 TI - Commentary on a proposed TSH reserve test. PMID- 4160939 TI - [Immunohistochemical study of the plasmacytes of normal human intestinal mucosa]. PMID- 4160940 TI - [Hormone-binding proteins]. PMID- 4160941 TI - [Hypergammaglobulinemia]. PMID- 4160942 TI - Antibody active sites and immunoglobulin molecules. AB - In order to obtain detailed information about the relationship between structure and function in antibody molecules, a method called affinity labeling has been devised to attach chemical labels specifically to amino acid residues in the active sites of antibody molecules. With antibodies to three different haptens, highly specific labeling of the active sites has been achieved. Tyrosine residues on both heavy and light polypeptide chains have been labeled in a molar ratio close to 2:1, and labels on the two chains are equally specific to the active sites. Peptide fragmentation studies of the labeled chains of one antibody system have shown that: (i) within 25 amino acid residues of the labeled tyrosine on either chain, substantial chemical heterogeneity exists among different antibody molecules of the same specificity; and (ii) the labeled peptide fragments from both chains are very similar in physicochemical characteristics, including average size, heterogeneity, and unusual hydrophobicity. These experimental results have led us to the view that a particular region of the heavy chain and a particular region of the light chain are utilized to construct the active sites of the three different antibodies, differences in specificity arising from chemical perturbations in these two regions. Correlated structural studies of affinity-labeled antibodies and of the homogeneous light chains (Bence Jones proteins) and heavy chains produced in multiple myeloma may permit the identification of these special active-site regions. The view that active sites of different specificity are chemical perturbations of a particular region of the antibody molecule has a possible close analogue in enzyme systems, particularly among the esterases. The marked chemical similarities we have observed between the active site regions of heavy and light chains indicate to us that chemical homologies, but not identities, exist between the chains. This is reinforced by recently obtained amino acid sequence data which reveal homologies between the two chains near their carboxyl-terminals. These results indicate that the structural genes which code for the synthesis of heavy and light chains are related, presumably having arisen from some common ancestral gene during evolution. This conclusion strongly suggests that both heavy and light chains determine antibody specificity, and has important implications for the still unknow mechanisms of antibody biosynthesis. PMID- 4160943 TI - Antiserum to immunoglobulin A: Inhibition of cell-mediated demyelination in tissue culture. AB - Lymph node cells from rats immunized with sciatic nerve in Freund's adjuvant demyelinate trigeminal ganglion cultures. Rabbit antiserum to rat immunoglobulin A blocks this cytodestructive event. The antiserum may act by combining with IgA on the lymphoid cell surface, preventing the interaction of cell-bound antibody and tissue anitigen. PMID- 4160944 TI - 10-Demethylation of testosterone by human prostate, in vitro. PMID- 4160945 TI - [Cytochemical investigations of Kulczycki's cells in the epithelium of the duodenum of albino rats]. PMID- 4160946 TI - The role of calcium and magnesium ions in invasiveness of schistosome cercariae. PMID- 4160947 TI - [Furo(3,2-c)coumarins from 3-propinyl-4-hydroxycoumarins]. PMID- 4160948 TI - [The dependence of the secretory cycle of the striated submandibular gland parts on the ovarian cycle in the white mouse]. PMID- 4160949 TI - Intestinal lipodystrophy (Whipple's disease): a cause of unexplained fever. PMID- 4160950 TI - [Evaluation of rapid method of determination of the prothrombin time]. PMID- 4160951 TI - Cardiopulmonary effects of tobacco and related substances. I. The release of histamine during inhalation of cigarette smoke and anoxemia in the heart-lung and intact dog preparation. PMID- 4160952 TI - [Early detection of dental caries]. PMID- 4160953 TI - The immunoglobulins in congenital rubella. PMID- 4160954 TI - A mammalian equivalent of the avian bursa of Fabricius. PMID- 4160955 TI - Liver function after myocardial infarction. PMID- 4160956 TI - Effect of urinary pH on excretion of porphyrins. PMID- 4160957 TI - Steroid therapy and strongyloidiasis. PMID- 4160958 TI - Clinical recognition of hypoxaemia under fluorescent lamps. PMID- 4160959 TI - Spontaneous descent of the testicle. PMID- 4160961 TI - Osteomalacia after gastrectomy. PMID- 4160960 TI - A press-stud electrode for continuous monitoring of the electrocardiogram. PMID- 4160962 TI - Thymus and bursa. PMID- 4160963 TI - Air pollution and respiratory infection in children. PMID- 4160964 TI - Third thoughts. PMID- 4160966 TI - Brucellosis in East Africa. PMID- 4160965 TI - B.C.G., U.S.A. PMID- 4160967 TI - A success story. PMID- 4160968 TI - Regional lymph-nodes in malignant melanoma. PMID- 4160969 TI - Staffing of clinical biochemistry laboratories serving the National Health Service. PMID- 4160970 TI - The teaching potential of a home-care unit. PMID- 4160971 TI - [Investigations on the tolerability of intravenously administered homologous antibodies. Combined application of gamma globulin and heat-inactivated human plasma-protein solution]. PMID- 4160972 TI - [On carmine-positive substances in the central nervous system. A contribution to the problem of glycogen metabolism disorders in hepatocerebral diseases]. PMID- 4160973 TI - Lactate in cerebrospinal fluid during muscular exercise. PMID- 4160974 TI - Lactate in cerebrospinal fluid during hyperventilation. PMID- 4160975 TI - Excitatory and depressive phenomena in the olfactory system of the sloth (Choloepus hoffmani Peters). PMID- 4160976 TI - [Active transport and passive permeability at the level of the cornea in the toad, Bufo marinus L]. PMID- 4160977 TI - Hydroxytryptaminergic transmission in a frog vagus-stomach muscle preparation. PMID- 4160978 TI - [Apropos of the gastrin content of hyperstimulated antra]. PMID- 4160979 TI - [Action of so-called selective vagotomy and total vagotomy on biliary and pancreatic secretions]. PMID- 4160980 TI - Hypothalamic control of coronary circulation in the dog. PMID- 4160981 TI - Changes of aspartic acid in various cerebral structures of hibernating and aroused ground squirrels. PMID- 4160982 TI - [Adipokinetic effect of anaphylactic shock in guinea pigs]. PMID- 4160983 TI - [Manifestations, in normal man, of the electrical response of the diaphragmatic pillars to electric stimulation of the phrenic nerves by single shocks]. PMID- 4160984 TI - [New theoretical remarks on the subject of corporeal plethysmography applied to the study of pulmonary ventilation]. PMID- 4160985 TI - [Relations existing between thyroid-stimulating and exophthalmogenic activities of a bovine pituitary extract]. PMID- 4160986 TI - Cortical activation of pyramidal tract during the sleepwakefulness cycle. PMID- 4160987 TI - Thalamic transmission changes during the rapid eye movements of deep sleep. PMID- 4160988 TI - [Catalepsy-inducing action of paramethoxy (2-methylaminopropyl) benzene]. PMID- 4160989 TI - The effect of intracarotid amobarbital injections upon experimentally induced epileptiform activity. PMID- 4160990 TI - Electrical stimulation of therapeutic targets in waking dyskinetic patients. PMID- 4160991 TI - Post-primary cortical responses to flashes and their specific potentiation by steady light. PMID- 4160992 TI - An analysis of cingulate gyrus response to cingulum stimulation in the cat. PMID- 4160993 TI - The volume conduction of motor unit potentials. PMID- 4160994 TI - Infrared thermograph studies of cortical circulation: evaluation of the method. PMID- 4160995 TI - A method for attaching apparatus to the skull. PMID- 4160996 TI - Estrogenic management of benign prostatism, including early and poor-risk cases. 7-year experience. PMID- 4160997 TI - [Clinical observations on prostatic hypertrophy and cancer: Okayama University Medical School in the recent eight years]. PMID- 4160998 TI - Biosynthesis of gamma globulin: studies in a cell-free system. AB - Incorporation of C(14)-amino acids into high-molecular-weight material precipitable by trichloroacetic acid indicates that microsomal cell-free systems, derived from spleens of immunized rabbits, are active in protein synthesis. Protein was made soluble by ultrasonic irradiation of the cell-free incubation mixtures, and low-molecular-weight materials were removed by dialysis and gel filtration. Chromatography and radio-immunoelectrophoresis of this soluble protein fraction reveal C(14)-labeled protein having several characteristics of gamma globulin. PMID- 4160999 TI - Hepatic synthesis of alpha 2 (acute phase)-globulin of rat plasma. AB - Synthesis of plasma alpha(2) (acute phase)-globulin was demonstrated in isolated perfused rat liver obtained from animals showing acute inflammatory reaction to injury. These findings indicate that the liver is a source of the globulin and that appearance of this protein in the serum results from de novo synthesis by the liver rather than from release of performed and stored globulin. PMID- 4161001 TI - Innovations in the teaching of anatomy. PMID- 4161000 TI - Sensitivity to P-T-C among primates. PMID- 4161002 TI - Biomedical communication: crisis and plan for action. PMID- 4161003 TI - The synthesis of foetal chicks and rats of serum proteins having some properties of the immunoglobulins. PMID- 4161004 TI - Growth of diploid and heteroploid tissue cultures in the presence of some antibiotics. PMID- 4161005 TI - [Subacute Hodgkin's disease with increased myeloid hyperleukocytosis--interesting palliative effect of marrow fraction FM1A, gamma globulin and beta-lipoproteins]. PMID- 4161006 TI - The effect of heparin on nuclear immunofluorescence. PMID- 4161007 TI - A simple model for the in-vivo function of antibody. PMID- 4161008 TI - Proteolysis of fluoresceinated proteins. PMID- 4161009 TI - Production of gamma-1- and gamma-2-antiovalbumin by various lymphoid tissues of the guinea pig. PMID- 4161010 TI - A study of soluble complexes and uncombined material in antigen-antibody reactions involving allotypic specificities of purified rabbit gamma-globulin. PMID- 4161011 TI - Components of fraction 3 and pepsin-digested fraction 3 from papain-digested rabbit gamma-globulin. PMID- 4161012 TI - Reaginic activity associated with IgG immunoglobulin. AB - Five human sera with reaginic activity to a number of allergens were fractionated using anion exchange chromatography. In each serum, fractions which contained detectable IgG and no detectable IgA had capacity to fix to skin and subsequently elicit a P-K reaction. Four of these sera had reaginic activity about equally distributed between fractions containing only IgG and fractions containing mixtures of IgG and IgA. A fifth serum contained reaginic activity to crystalline bovine serum albumin (BSA) and most of the activity was associated with the fraction which contained only IgG. This serum was extensively studied using a variety of techniques and it was confirmed that most of the reagin to BSA in this serum was in those fractions containing only IgG. Since reaginic activity can no longer be considered a unique property of IgA the implications of finding antibody with reaginic qualities in immunoglobulins other than IgA are discussed. PMID- 4161013 TI - Gamma-A-blood group antibodies. AB - The serological characteristics of gammaA-anti-A and anti-B were studied using, as a source, either colostrum, or fractions relatively rich in gammaA obtained from selected potent antisera. gammaA-anti-A and anti-B were never hemolytic nor did they sensitize red cells to agglutination by anticomplement globulin sera. gammaA-anti-A, like gammaG-anti-A and unlike gammaM-anti-A was unaffected by heating at 56 degrees C for 3 hr. On the other hand in the following three characteristics the behavior of gammaA fell between that of gammaG- or gammaM anti-A: sensitivity to inactivation by 2-mercaptoethanol, ease of neutralization by A substance and degree of enhancement of agglutination in a medium of serum rather than saline. The agglutination produced by gammaA-anti-A was regularly enhanced by addition of anti-gammaA-globulin serum. In searching for gammaA-blood group antibodies of other specificities the following sera were tested: anti-D (32 examples); anti-c (2 examples); anti-Le(a) or -Le(b) (3 examples); anti-K (3 examples); anti-Fy(a) (3 examples), and anti-Jk(a) (3 examples). Only 3 sera, all containing anti-D, sensitized red cells to agglutination by anti-gammaA. There were no discrepancies between results obtained with four different anti-gammaA globulin sera. Approximately half the sera were fractionated on DEAE-cellulose, and the fractions rich in gammaA tested for their ability to sensitize red cells to agglutination by anti-gammaA; no additional examples of gammaA-antibodies were detected. One of the three examples of gammaA-anti-D appeared in the serum of a woman during the course of deliberate reimmunization. gammaA-anti-D appeared only after three intravenous injections of red cells although the gammaG-anti-D titer rose considerably after a single injection. 3 yr after a fourth injection of Rh positive cells gammaA-anti-D, as well as gammaG-anti-D, was still present in the serum. PMID- 4161014 TI - Transformation products of 5H-dibenzo-[a,d]-10,11-dihydrocyclohepten-5-one. PMID- 4161015 TI - Chromosomes in Kostmann's disease. PMID- 4161016 TI - Karyotype of treated thrombocythemia. PMID- 4161017 TI - Deleted late-replicating chromosomes. PMID- 4161018 TI - Sex chromatin after cytostatic drugs. PMID- 4161019 TI - Pulmonary veno-occlusive disease. PMID- 4161020 TI - The bleeding disorder of uraemia. A qualitative platelet defect. PMID- 4161021 TI - Chromosome studies on testicular cells from 50 subfertile men. PMID- 4161022 TI - Idiopathic haemochromatosis in a family. PMID- 4161023 TI - Pulmonary complications of peritoneal dialysis. PMID- 4161025 TI - Phosphaturic effect of thyrocalcitonin. PMID- 4161024 TI - Intermittent therapy with corticotrophin. PMID- 4161026 TI - Rhesus-immunised mothers and direct-coombs-test-negative babies. PMID- 4161027 TI - Renal clearance of 57-Co-cyanocobalamin. Importance of plasma-protein binding. PMID- 4161028 TI - Intrinsic -factor antibodies in gastric juice of pernicious - anemia patients. PMID- 4161029 TI - Serum-growth-hormone in acromegaly. Effect of cryogenic pituitary destruction. PMID- 4161030 TI - The Aldon intestinal deflation tube. PMID- 4161031 TI - Training of pathologists. PMID- 4161032 TI - Diagnosis of renovascular hypertension. PMID- 4161033 TI - The geography of multiple sclerosis. PMID- 4161035 TI - [Chlormadinone]. PMID- 4161034 TI - Management, during dental surgery, of patients on anticoagulants. PMID- 4161036 TI - Use of potassium permanganate as a fixative for virus particles in plant tissues. PMID- 4161037 TI - Staining of the thyroid gland with ferritin-conjugated antithyroglobulin. PMID- 4161038 TI - Clinical observations on prostatic hypertrophy of 268 cases in the recent 15 years. PMID- 4161039 TI - [Histochemical and electron optical findings on biopsy material in Whipple's disease]. PMID- 4161040 TI - Physicochemical properties of complexes between deoxyribonucleic acid and antibiotics which affect ribonucleic acid synthesis (actinomycin, daunomycin, cinerubin, nogalamycin, chormomycin, mithramycin, and olivomycin). PMID- 4161041 TI - Polypeptide chain structure of rabbit immunoglobulins. I. gamma-G-immunoglobulin. PMID- 4161042 TI - Polypeptide chain structure of rabbit immunoglobulins. II. gamma-M immunoglobulin. PMID- 4161043 TI - Aggregation of IgG globulin in vivo. II. Physicochemical properties of the isolated protein. PMID- 4161044 TI - Observations on the lipolytic action in vitro of a fat-mobilizing substance extracted from urine of fasting rats. PMID- 4161045 TI - Factors influencing the excretion of a fat-mobilizing substance in the urine of rats. PMID- 4161046 TI - [Cold staining of tubercle bacilli--a progress compared to conventional hot staining methods?]. PMID- 4161047 TI - Jejunal bacteriology and bile-salt metabolism in patients with intestinal malabsorption. PMID- 4161048 TI - Transferable R factors in enteric bacteria causing infection of the genitourinary tract. PMID- 4161049 TI - Mortality in neonatal duodenal obstruction. PMID- 4161050 TI - Reflections on cardiopulmonary resuscitation. PMID- 4161051 TI - Ambilhar in amoebic dysentery and amoebic liver abscess. PMID- 4161052 TI - Extra minute chromosome in somatic and germ-line cells of the same person. PMID- 4161053 TI - Effect of secretin on insulin secretion. PMID- 4161054 TI - Effects of secretin on insulin and glucagon in portal and peripheral blood in man. PMID- 4161055 TI - Rubidomycin. A new agent active in the treatment of acute lymphoblastic leukaemia. PMID- 4161056 TI - Kuru as a persisting tolerated infection. PMID- 4161057 TI - Vein tester and stretcher. PMID- 4161058 TI - Cancer research: is progress too slow? PMID- 4161059 TI - Toxicity of tannic acid. PMID- 4161061 TI - Congenital word blindness. PMID- 4161060 TI - Intestinal hormones and insulin. PMID- 4161062 TI - Injection accidents in industry. PMID- 4161063 TI - Control of smallpox. PMID- 4161064 TI - The first fourteen days of some west African babies. PMID- 4161065 TI - B.M.A'S views on abortion. PMID- 4161067 TI - Pathological fracture. PMID- 4161068 TI - Dissociation of delayed-hypersensitivy and antibody-synthesising capacities in man. Report of two sibships with thymic dysplasia, lymphoid tissue depletion, and normal immunoglobulins. PMID- 4161069 TI - Haemodynamic effects of physical training in coronary patients. PMID- 4161070 TI - The normal synthesis, catabolism, and distribution of albumin and gamma-globulin. PMID- 4161071 TI - Pathophysiology of plasma proteins with special reference to hypoproteinaemic states. PMID- 4161072 TI - The total clearance of different gammaglobulin preparations. PMID- 4161073 TI - Precipitation methods and large-scale methods. PMID- 4161074 TI - Isolation of gamma-A-globulin as by-product of large-scale fractionation. PMID- 4161075 TI - Immunochemical determination of plasma proteins. PMID- 4161076 TI - The stimulation of hydroxylation by carcinogenic and non-carcinogenic compounds. PMID- 4161077 TI - Thyrotoxicosis, hyperparathyroidism, and hyperuricaemia. PMID- 4161079 TI - [Basedow's disease]. PMID- 4161078 TI - Diseases of the heart and blood-vessels. Ischaemia of the lower limbs. PMID- 4161080 TI - [Purification of gamma-globulins. A new method using glycine-rich solvent systems]. PMID- 4161081 TI - [Fuchsinic index of the oral cavity hygiene]. PMID- 4161082 TI - [Lipids of brain tumors]. PMID- 4161083 TI - [The autonomic nervous system in ulcerative colitis]. PMID- 4161084 TI - [Release of biologically active polypeptides from the chromatographic fractions of alpha- and beta-pseudoglobulins]. PMID- 4161085 TI - The relation of covert cognitive interference in the color-phonetic symbol test to personality characteristics and adjustment. PMID- 4161086 TI - [Normal and abnormal interactions of gamma-G-globulins with iodine]. PMID- 4161087 TI - Demineralization with EDTA by constant replacement. PMID- 4161088 TI - The cell web in the ameloblasts of the rat incisor. PMID- 4161089 TI - Ultraviolet fluorescence of bladder tumors following oral administration of tetracycline compounds. A macroscopic, microscopic and fluorescence spectrophotometric study. PMID- 4161090 TI - Effects of antitumor agents and hyperbaric oxygen in normal and tumor-bearing rodents. PMID- 4161091 TI - Cytology and histopathology of cervical herpes simplex infection. PMID- 4161092 TI - Comparative histochemical studies of L-leucyl beta-naphthylamidase in ovarian epithelial tumors. PMID- 4161093 TI - Histochemical study of the enzymatic activity of human neoplasms. 3. Structural functional relationships in a hepatoma. PMID- 4161094 TI - Histochemical study of the enzymatic activity of human neoplasms. II. Histogenesis of renal cell carcinoma. PMID- 4161095 TI - Studies on diazabenzobicyclo[3.3.1]nonane system. IV. Synthesis of 1,2,3,4,5,6, hexahydro-1,5-methanobenzo[e][1,3]diazocine derivatives. PMID- 4161096 TI - [Determination of the synthesis of poliovirus antigens with the use of gamma globulin labled with I-131]. PMID- 4161097 TI - [Pharmacology of 3-phenylazetidine and of some of its derivatives]. PMID- 4161098 TI - [Studies on the biosynthesis of proteins. VI. A new method in the preparation of a cellfree system from Escherichia coli and its properties in nucleic acid dependent protein synthesis]. PMID- 4161099 TI - Prednisone in emergency treatment of malignant exophthalmos. PMID- 4161100 TI - Chromosomal abnormalities in idiopathic osteoarthropathy. PMID- 4161101 TI - A comparison of tetracycline fluorescence and exfoliative cytology in the detection of malignancy. PMID- 4161102 TI - Collagenolytic activity of the skin associated with neuromuscular diseases including amyotrophic lateral sclerosis. PMID- 4161103 TI - Chemical test for bilirubin in liquor amnii. For assessment of prognosis in rhesus isoimmunisation. PMID- 4161104 TI - The management of dry skin in leprosy patients. PMID- 4161105 TI - Job's Syndrome. Recurrent, "cold", staphylococcal abscesses. PMID- 4161106 TI - Loss of ejaculation in male rhesus monkeys after administration of progesterone to their female partners. PMID- 4161107 TI - The third type of nucleic-acid-directed protein synthesis. PMID- 4161108 TI - Muscle spindles. PMID- 4161109 TI - The lymphocyte. PMID- 4161110 TI - Oropharyngeal cancer in India. PMID- 4161111 TI - Greenwich district hospital. PMID- 4161112 TI - Effect of oral streptokinase on antibody and antiplasmin levels. PMID- 4161113 TI - Effects of a gastrin-like pentapeptide (I.C.I. 50,123) on stomach and pancreas. PMID- 4161114 TI - The effect of a synthetic gastrin-like pentapeptide (I.C.I. 50,123) on intestinal motility in man. PMID- 4161115 TI - Circulatory effects of a synthetic gastrin-like pentapeptide (I.C.I. 50,123). PMID- 4161116 TI - Mathematics and creative thinking. PMID- 4161117 TI - Microfluorometric characterization of intracellular nucleic acids and nucleoproteins by acridine orange. PMID- 4161118 TI - [Presence in the mitochondria of a factor inhibiting the production of antibodies and other cellproteins]. PMID- 4161119 TI - [Visual aids in health education]. PMID- 4161120 TI - Further studies of learning and memory after intracerebral actinomycin-D. PMID- 4161121 TI - Cause of raised serum-alkaline-phosphatase after partial gastrectomy and in other malabsorption states. PMID- 4161122 TI - [Malignant lymphoma and plasma proteins]. PMID- 4161123 TI - Methods for teaching basic rehabilitation techniques to nonprofessional staff. PMID- 4161124 TI - Proteus: the quiet sort. PMID- 4161125 TI - Female carriers of muscular dystrophy. PMID- 4161126 TI - Immunoelectrophoretic study of serum proteins in mongolism. PMID- 4161127 TI - Contribution to the morphological study of dendritic arborization in the brain stem. PMID- 4161128 TI - [Remarks on changes in electron microscopic sections by decreasing electron beam and on the structure of inbedded tissues]. PMID- 4161129 TI - Formation of complexes between basic proteins of leucocytes and plasma globulins. PMID- 4161130 TI - Staining of blood smears. 7. PMID- 4161131 TI - [Considerations on palliative operations in severe congenital cardiopathies in infants]. PMID- 4161132 TI - Cytochemical localization of pancreatic lipase with light and electron microscopy. PMID- 4161133 TI - Immuno-diazothioether-osmium tetroxide (immuno-DTO) technique for staining embedded antigen in electron microscopy. PMID- 4161134 TI - Post-embedding staining for electron microscopy with ferritin-antibody conjugates. PMID- 4161135 TI - Formation of vaccinia antigen studied by immunouranium and immuno-diazothioether osmium tetroxide techniques. PMID- 4161136 TI - Selectivity of ferritin-protein conjugates for sites on skeletal muscle. PMID- 4161137 TI - [Studies on the metabolism of phytol, dihydrophytol and phytanic acid]. PMID- 4161138 TI - [Actinomycins, XXV; antibiotics from actinomycetes, LIV. Actinomycin Z-1. On the quantitative amino acid analysis of actinomycins]. PMID- 4161139 TI - Tryptic digestion of rabbit gamma-globulin. PMID- 4161140 TI - [Immunity of pregnant women, fetus and newborn infant]. PMID- 4161141 TI - [Arrhythmia in myocardial infarct]. PMID- 4161142 TI - A light scattering technique for measuring protein concentration. PMID- 4161143 TI - [Clinical aspects of immunoglobulins]. PMID- 4161144 TI - Immunoglobulin M allotypes of the rabbit: identification of a second specificity. AB - Rabbit antiserums, originally prepared to react specifically with rabbit immunoglobulin allotypes Ab5 and Ab6, also react with some normal rabbit serums that clearly do not contain Ab5 or Ab6 allotypes. This reaction is due to antigenic specificity present on rabbit immunoglobulin M(IgM) and not on rabbit immunoglobulin G. Serums that contain this IgM allotype do not react with an antiserum that reacts with the known rabbit IgM allotype, Ms1. This specificity may therefore be identified as a second rabbit IgM allotype, Ms2. PMID- 4161145 TI - Subclasses of human immunoglobulin a based on differences in the alpha polypeptide chains. AB - Antiserum from goats immunized with heavy polypeptide chains from a gammaA-type myeloma globulin was absorbed with serum from patients with selective absence of immunoglobulin A (gammaA). The resulting reagents could be used for the classification of 58 gammaA-myeloma proteins into two distinct antigenic types, respectively called subclasses He and Le. These differences were shown to be related to the heavy (alpha) polypeptide chains and independent of the integrity of interchain disulfide bridges. The gammaA-immunoglobulin from normal serum appears to consist, for the most part, of molecules with Le subclass specificity. PMID- 4161146 TI - Urinary gamma-globulin excretion in systemic lupus erythematosus. PMID- 4161147 TI - A study of in vitro incorporation of tetracycline antibiotics into avian and mammalian blood cells. PMID- 4161148 TI - [Experimental investigations of the mechanism of sedimentation of blood corpuscles]. PMID- 4161149 TI - [Animal experimental studies of the formation of anti-erythrocyte autoantibodies]. PMID- 4161150 TI - 5'-Nucleotidase activity in human blood granulocytes during acute infections. PMID- 4161151 TI - [Cytochemical investigations and function tests of the bone marrow in hemoblastosis bone marrow insufficiency]. PMID- 4161152 TI - [Comparative investigations of the value of puncture methods in the diagnosis of panmyelopathies]. PMID- 4161153 TI - [Normal blood values of African clawed toad, Xenopus laevis (Daudin)]. PMID- 4161155 TI - Negative staining of ultrathin secretion. PMID- 4161154 TI - [The volume ratio of erythrocytes to plasma as a regulator of hemostasis]. PMID- 4161156 TI - Towards responsible parenthood. The education of the educators. PMID- 4161157 TI - Slowing of cerebral circulation after concussional head injury. A controlled trial. PMID- 4161158 TI - Postoperative changes in gas tensions of arterial blood and in ventilatory function. PMID- 4161159 TI - Effects of cigarette smoking on serum-lipids, blood-glucose, and platelet adhesiveness. PMID- 4161160 TI - Frequency-distribution curve of uric acid in the general population. PMID- 4161161 TI - Absence of prophylactic effect of linolenic acid in patients with coronary heart disease. PMID- 4161162 TI - Gastric acid secretion in chronic iron-deficiency anaemia. PMID- 4161163 TI - Phenylketonuria among the mentally retarded in India. PMID- 4161165 TI - Calcium, phosphorus, and fatty acids in plasma stored at room temperature. PMID- 4161164 TI - The triphenyl tetrazolium chloride test in general-practitioner antenatal care. PMID- 4161166 TI - Solitary pyogenic liver abscess in patients with diabetes mellitus. PMID- 4161167 TI - Heterogeneity of lymphocytes in chronic lymphocytic leukaemia. PMID- 4161168 TI - Temperature control in incubators. PMID- 4161169 TI - Decreasing alveolar size from apex to base in the upright lung. PMID- 4161170 TI - Experimental homotransplantation of the knee-joint. PMID- 4161171 TI - Experimental cholera. A canine model. PMID- 4161173 TI - Epidemics of acute leukaemia. PMID- 4161172 TI - Postoperative hypoxaemia. PMID- 4161174 TI - Survival of children with nephroblastoma. PMID- 4161175 TI - Overdoses from linear accelerator. PMID- 4161176 TI - Milk-borne diseases. An epidemiological review. PMID- 4161177 TI - Measurement of gastric emptying-rate. PMID- 4161178 TI - Long marker chromosome in bronchogenic carcinoma. PMID- 4161179 TI - Chromosomes in chronic lymphocytic leukaemia. PMID- 4161180 TI - Chromosomes in cleft-palate tissues. PMID- 4161181 TI - Serum-vitamin-B12 and chlorpromazine. PMID- 4161182 TI - Mitogenic action of trypsin and chymotrypsin. PMID- 4161183 TI - [Normal metabolism of gamma G globulin]. PMID- 4161184 TI - [Iodine conversion in long-term treatment with antithyroid drugs]. PMID- 4161185 TI - [Content of the embryo-specific alpha-globulin in the serum of the fetus, newborn infant and adult man with primary liver cancer]. PMID- 4161186 TI - Canine mastocytoma: altered alpha-globulin distribution. PMID- 4161187 TI - WHO-supported comparative studies of attenuated live measles virus vaccines. AB - UNDER THE AUSPICES OF WHO A COMPARATIVE STUDY OF ATTENUATED LIVE MEASLES VACCINES WAS MADE BY TEAMS IN FIVE COUNTRIES: Canada, Czechoslovakia, Nigeria, Switzerland and Yugoslavia. The reactions and antibody responses to Enders' Edmonston B vaccine with or without gamma-globulin and to the Schwarz, Beckenham and Milovanovic vaccine were measured. In each trial Enders' Edmonston B vaccine with gamma-globulin was used as a "standard" vaccine, and in each trial there was also an unvaccinated control group. There were altogether 1685 children in the study 1317 vaccinated and 368 controls.Each team placed the vaccines in a similar order as to the percentages of children with rash and pyrexia after vaccination. The percentages of children with rash and pyrexia after injection of the same vaccine were, however, found to vary greatly between trials. It was therefore impossible to give accurate figures for the percentage of children who would develop pyrexia after any one vaccine, but in general terms the proportion of children with fever of 39.4 degrees C (103 degrees F) or more may be expected to vary from 10% to 30% depending on the vaccine used. Six of the vaccinated children (0.5%) had convulsions 6-9 days after vaccination, but no other serious reactions and no permanent sequelae were recorded. No convulsions occurred in the unvaccinated control groups. The antibody responses were measured by the haemagglutination inhibition test; nearly all children gave an antibody response but this varied with the vaccine employed. Children given vaccines causing the most reaction had the highest antibody levels. PMID- 4161188 TI - [Nomenclature of genetic factors supported by human immunoglobulins]. PMID- 4161189 TI - [An examination of the reticulocyte staining method: a comparison of the Brecher method and a variation of the Kammerer method and also the use of Miller ocular disc]. PMID- 4161190 TI - Immunochemical semiquantitative estimation of gamma-M- and gamma-A immunoglobulins in healthy and diseased children. 3. Immunoglobulin levels in infectious diseases, allergic diseases, collagen diseases and liver cirrhosis. PMID- 4161191 TI - Placental transmission of autoimmune diseases. PMID- 4161192 TI - Ligation of the main pulmonary artery and systemic-pulmonary arterial anastomosis. A new palliative operation for complete transposition of the great arteries. PMID- 4161193 TI - Evoked potentials and reaction times: a study of intra-individual variability. PMID- 4161194 TI - Intracellular potentials from "idle" cells in cerebral cortex of cat. PMID- 4161195 TI - Prevalence of hallux valgus in a neolithic New Guinea population. PMID- 4161196 TI - Oral contraceptives and thyroid function tests. PMID- 4161197 TI - Cytochemical localization of lactate dehydrogenase in muscular dystrophy of the mouse. AB - By use of phenazine methosulfate and the "ncubation mixture film method," lactate dehydrogenase activity has been demonstrated in the dystrophic muscle fibers of strain 129 mice. The results indicate that for demonstration of lactate dehydrogenase activity in dystrophic muscle fibers phenazine methosulfate is necessary. This finding is typical for the "white" muscle fibers in the normal muscle and suggests that the dystrophy affects primarily the "white" muscle fibers. PMID- 4161198 TI - [Fluorescence serological demonstration of coli dyspepsia in routine operation. Problems of economy and technique]. PMID- 4161199 TI - Specificity in the combination of Fd fragments with L chains to form hapten binding sites. AB - In the work reported here we have shown that light chains and Fd fragments can be separated completely in propionic acid and then recombined to form Fab fragments with antibody activity. This experiment indicates that in the recombination a correct alignment of the Fd fragments and the L chains occurs to give a competent antibody site, just as occurs with the recombination of separated heavy and light chains of the antibody; thus the Fc fragment is not required for correct alignment. Fd fragments of antibody alone show very low binding activity toward the specific hapten. As is the case for the combination of heavy and light chains, the combination of Fd fragments and light chains also requires that both components come from antibody from the same rabbit in order to give binding sites. When they are derived from different rabbits producing antibody against the same antigen, they still give Fab fragments as shown by immunoelectrophoresis but do not have competent binding sites. An important observation is that the subunits of the papain digest fractions, Fab(I) and Fab(II), have the capacity to cross-combine to form active Fab fragments with competent binding sites. Fd(I) from Fab(I) combines with L(II) chains from Fab(II) to give the composite (Fd(I) L(II)) with good binding activity. Likewise, the composite (Fd(II)-L(I)) has good binding activity. The composites from the two types of antibody molecules yielding different Fab fragments have antibody activity although heretofore these molecules have appeared to be different on the bases of chromatography and amino acid analysis. There is also a preferential combination of the Fd fragments to combine with the correct L fragments to give binding sites since this combination takes preference over the combination of Fd fragments of antibody with light chains of normal globulin (or of light chains of antibody with Fd fragments of normal globulin). PMID- 4161200 TI - Relationship of some vibrio antibodies to serum immune globulins in man and in Cercopithecus aethiops. PMID- 4161201 TI - Is our pathology really necessary? Parkinson versus Beeching. PMID- 4161202 TI - Myeloma cells and immunoglobulin formation. PMID- 4161203 TI - [Effect of the polypeptide kallikrein on the cholesterol and protein-bound iodine serum level of hypercholesteremic rats]. PMID- 4161204 TI - The politics of pollution. PMID- 4161205 TI - Fatal granulomatous disease of childhood. An inborn abnormality of phagocytic function. PMID- 4161206 TI - Endocrine studies in African males with nasopharyngeal cancer. PMID- 4161207 TI - The excretion of foriminoglutamic acid and urocanic acid after partial gastrectomy. PMID- 4161208 TI - Urinary insulin excretion in healthy children and in siblings of childhood-onset diabetics. PMID- 4161209 TI - The deconjugation of bile salts by human intestinal bacteria. PMID- 4161210 TI - Therapeutic suggestion. An important part of hypnotic medication. PMID- 4161211 TI - Effect of thalidomide on survival of skin homografts in rabbits. PMID- 4161212 TI - A method of continuous measurement of arterial-oxygen tension. PMID- 4161213 TI - Measurement of rate of gastric emptying using chromium-51. PMID- 4161214 TI - The mechanism of acidosis caused by infusion of saline solution. PMID- 4161215 TI - Mechanism of water and electrolyte secretion by the eccrine sweat gland. PMID- 4161216 TI - Modification of Down's ileostomy appliance. PMID- 4161218 TI - Family likeness. PMID- 4161217 TI - Man in the control room. PMID- 4161219 TI - Maternal deaths. PMID- 4161220 TI - Effects of radiation from fallout. PMID- 4161221 TI - Family planning and the physician. PMID- 4161222 TI - Urine pH and drug excretion. PMID- 4161223 TI - The "loss of control" myth. PMID- 4161224 TI - Another chance for thalidomide? PMID- 4161225 TI - P.HA. and thymic lymphocytes. PMID- 4161226 TI - Phytohaemagglutinin and lymphocytes from acute lymphocytic leukaemia. PMID- 4161227 TI - Pulmonary blood-flow in lung cancer. PMID- 4161228 TI - Histamine metabolism in carcinoidosis. PMID- 4161229 TI - Gonadal dysgenesis and diabetes. PMID- 4161230 TI - Methyldopa and haemolytic anaemia. PMID- 4161231 TI - Enzymes in trisomy-18 syndrome. PMID- 4161232 TI - Mosaicism of X and G chromosomes. PMID- 4161233 TI - Metabolic changes after exercise. PMID- 4161234 TI - The electrocardiogram of neonatal hypoventilation. PMID- 4161235 TI - Serum protein formation of donor type in rat-into-mouse chimaeras. PMID- 4161236 TI - Properties of horse serum gamma inhibitor. PMID- 4161237 TI - Creatine phosphokinase isoenzymes. PMID- 4161238 TI - Use of galactose oxidase in the histochemical examination of mucus-secreting cells. PMID- 4161239 TI - Effect of trypsin inhibitor isolated from sows' colostrum on the absorption of gamma-globulin by piglets. PMID- 4161240 TI - [Experiences in the treatment of esophageal carcinomas]. PMID- 4161241 TI - The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man. PMID- 4161242 TI - Effect of dihydrostreptomycin on tissue lipid of guinea-pigs. PMID- 4161243 TI - [On the histochemistry of mucopolysaccharides and proteins in periplacental trophoblast in rabbits]. PMID- 4161244 TI - [Changes in ultraviolet and blue fluorescence of liver cells in white rats during the early postnatal period]. PMID- 4161245 TI - Cystathioninuria from pyridoxine deficiency complicating treatment of hypercalcaemia in a cretin. PMID- 4161246 TI - [The cytologic action of selenium dioxide during egg segmentation of Pleurodeles waltlii Michah]. PMID- 4161247 TI - [Serologic and immunohistological studies on sperm and sera from men with sterile marriages supplemented by animal experimental controls]. PMID- 4161248 TI - The effects of crude and purified gastrin preparations on the release of histamine from mast cells. PMID- 4161249 TI - Appearance of rat slow alpha-2 globulin after irradiation. PMID- 4161251 TI - [Hematological studies of blood-building tissues of lower vertebrates]. PMID- 4161250 TI - [In memory of Prof. Dr. med. Hans Schulten. July 25 1899-March 5, 1965]. PMID- 4161252 TI - [On cytology and cytogenesis of tissue eosinophils]. PMID- 4161253 TI - [Cytochemical modifications in phagocytosis. II. Changes in glucides and lipids in leukocytes during phagocytosis of staphylococcus aureus and citreus]. PMID- 4161254 TI - The investigation of the immunological reactivity of patients with haemoblastosis. PMID- 4161255 TI - [On the problems of transition of chronic myelosis into reticulum cell sarcoma]. PMID- 4161256 TI - [Denaturation of hemolyzed erythrocytes to globular formations in vivo and in vitro]. PMID- 4161257 TI - [Coagulation disturbances in vitro due to a peculiar inhibition body phenomenon. Studies on 68 cases that almost exclusively belong to a group of so-called collagen diseases]. PMID- 4161258 TI - [Clinical studies on the hemostatic effect of estriol]. PMID- 4161259 TI - [In memory of Prof. Dr. med. Karel Bobek. January 4, 1909 to November 24, 1964]. PMID- 4161260 TI - [Histological and histochemical findings in infant kidneys in nephrolithiasis. (Together with a contribution on formal stone formation)]. PMID- 4161261 TI - [Reticulocytoma of the nasopharyngeal space]. PMID- 4161262 TI - [Spermatozoa invasion-and granulomas of the epididymis]. PMID- 4161263 TI - [Histochemical demonstration of acid mucopolysaccharides in the visual cell layer of mammal retinas]. PMID- 4161264 TI - A modified Papanicolaou method for distinguishing degrees of keratinization in the oral mucosa using frozen tissues. PMID- 4161265 TI - The value of continuous saline rinses in mucoperiosteal flap surgery. PMID- 4161266 TI - "Yellow fat" in the wild rabbit. PMID- 4161267 TI - High antihaemophilic factor in multiple myeloma. PMID- 4161268 TI - Indications of the presence of organochlorine insecticides in rainwater in central England. PMID- 4161269 TI - Use of methylene blue for staining sialomucoproteins on paper. PMID- 4161270 TI - Fluorescent antibody studies in pemphigus vulgaris. PMID- 4161271 TI - Clinical significance of autoantibodies in pemphigus. PMID- 4161272 TI - Studies in immunoglobulin chemistry. I. Reinvestigation of the C-terminal amino acids of 6.5S rabbit and human gamma-globulins. PMID- 4161273 TI - (S)- and (R)-1-cyano-2-hydroxy-3-butene from myrosinase hydrolysis of epi progoitrin and progoitrin. PMID- 4161274 TI - Solubility of proteins in the presence of polysaccharides. PMID- 4161275 TI - [Immuno-serological study on the so-called "feeling of cold" (hiesho)]. PMID- 4161276 TI - [Immuno-serological study of the so-called "feeling of cold" (hiesho)]. PMID- 4161277 TI - Histochemical study of acid phosphatase activity in cerebral tumors. PMID- 4161278 TI - Vascular changes in senile brains. A micro-angiographic study. PMID- 4161279 TI - [Multiple sclerosis with Rosenthal's fibers]. PMID- 4161280 TI - Deposition of glycogen during the degeneration and regeneration of the sciatic nerves of rabbits. (Light and electron microscopic studies). PMID- 4161281 TI - [Comparative light and fluorescence microscopic studies of experimental allergic encephalomyelitis in guinea pigs]. PMID- 4161282 TI - The intramuscular nerve endings in muscular dystrophy. A biopsy study. PMID- 4161284 TI - [The influence of prostatic adenoma on the tonus of the bladder]. PMID- 4161285 TI - A staining method for proteins and dextrans on cellulose acetate. PMID- 4161283 TI - A study of the evolution of viral infection in experimental herpes simplex encephalitis and rabies by means of fluorescent antibody. PMID- 4161286 TI - Dependence of the chemical nature of antibodies on the net electrical charge of antigens. PMID- 4161287 TI - [Preparation of visual aids from plastmass]. PMID- 4161288 TI - [Thyroid gland function in cardiacs]. PMID- 4161289 TI - Cytochemical demonstration of histones and protamines. Mechanism and specificity of the alkaline bromphenol blue binding reaction. PMID- 4161290 TI - Fluorescence and viability of Proteus mirabilis stained directly with fluorescein isothiocyanate. AB - Grunberg, E. (Hoffman-La Roche, Inc., Nutley, N.J.), and R. Cleeland. Fluorescence and viability of Proteus mirabilis stained directly with fluorescein isothiocyanate. J. Bacteriol. 92:23-27. 1966.-Washed cell suspensions of Proteus mirabilis, under the proper conditions, stained well with fluorescein isothiocyanate with little or no loss of cell viability. The speed and intensity of the reaction was dependent on both the concentration of dye and pH. Within a range of pH 3.0 to 10.0, staining was most rapid at pH 5.0 to 6.0, with a slower and less intense reaction occurring at the other pH values. As the concentration of dye at either pH 5.0 or 9.0 was increased from 10 to 1,000 mug/ml, there was an increase in the rate of staining but a decrease in cell viability. After 24 hr of incubation at 4 C, pH 5.0, and a dye concentration of 10 mug/ml, all cells were stained, the majority exhibiting intense fluorescence with little or no loss of viability noted. In preliminary experiments with Staphylococcus aureus, similar results were obtained. Of various other fluorescent dyes tested, only rhodamine isothiocyanate was found to give satisfactory staining. PMID- 4161291 TI - Electrophoretic and immunoelectrophoretic studies of sera from normal, tuberculous, and noninfected tuberculin-sensitive guinea pigs. AB - Dardas, T. J. (Michigan State University, East Lansing), and V. H. Mallmann. Electrophoretic and immunoelectrophoretic studies of sera from normal, tuberculous, and noninfected tuberculin-sensitive guinea pigs. J. Bacteriol. 92:76-81. 1966.-Normal guinea pig serum was separated into seven fractions by electrophoresis on cellulose acetate membranes. Thirty antigens were found by immunoelectrophoresis: albumin, 6 alpha(1) globulins, 11 alpha(2) globulins, 6 beta(1) globulins, 5 beta(2) globulins, and gamma globulin. Hyper-alpha(2) globulinemia was detected in sera from guinea pigs 14 days after inoculation with viable virulent Mycobacterium bovis. An additional alpha(2) globulin, not demonstrable prior to infection, was detected concomitantly with the hyper alpha(2)-globulinemia by immunoelectrophoresis. The additional alpha(2) globulin was tentatively named alpha(2)-T. It persisted until the death of the guinea pigs. Neither hyper-alpha-globulinemia nor the alpha(2)-T antigen was detected by cellulose acetate electrophoresis and immunoelectrophoresis of sera from guinea pigs sensitized with heat-killed M. bovis. Both changes were due to the disease, not to delayed sensitivity alone. PMID- 4161292 TI - Lymphochromography in female pelvic cavity. PMID- 4161293 TI - Side effects of treatment of hypogammaglobulinaemia with gammaglobulin. PMID- 4161294 TI - The clinical manifestations of temporal arteritis. PMID- 4161295 TI - Mode of action of certain myelin stains. PMID- 4161296 TI - Anaphylaxis in the cat. PMID- 4161297 TI - Gamma globulin catabolism by the kidney. PMID- 4161298 TI - Gastrointestinal motility function related to thyroid activity. An experimental study in the rat. PMID- 4161299 TI - [Clinical experiences with the complement consumption test for the demonstration of tissue antibodies]. PMID- 4161300 TI - [Treatment of CEP (chronic evolutive polyarthritis) by immunosuppressive substances. Clinical and immunological study]. PMID- 4161301 TI - [Action of an inhibitor of histidine decarboxylase on the liberation and reconstitution of cutaneous histamine in rats]. PMID- 4161302 TI - The ultrastructural basis for the identification of cell types in the pancreatic islets. I. Guinea pig. PMID- 4161303 TI - [A flocculation method for gram differentiation of bacteria without gram staining]. PMID- 4161304 TI - [Features of histological and histochemical observations on experimental triamcinolone myopathy in the rabbit]. PMID- 4161305 TI - [Comparative cytomorphologic and cytochemical vital staining attempts in high moor algae]. PMID- 4161306 TI - The cultured lymphocytes of atopic patients. PMID- 4161307 TI - Immunologic responses and "altered reactivity" in syphilis. PMID- 4161308 TI - [Screening test for the detection of high iodine levels in human serum]. PMID- 4161309 TI - Individuality of glycoproteins in human aorta. PMID- 4161311 TI - The in vivo formation and fate of antigen-antibody complexes formed by fragments and polypeptide chains of rabbit gamma-G-antibodies. AB - The in vivo formation and subsequent fate of complexes formed between specific rabbit gammaG-antibody subunits and circulating protein antigens was studied in rabbits and guinea pigs. Subunits obtained from purified antibodies were injected immediately after an injection of antigen, and the elimination from the circulation of either I*-labeled gammaG-subunits or labeled antigen determined. In the absence of antigen, all gammaG-subunits which lack the Fc fragment were rapidly eliminated. In the presence of excess antigen, F (ab')(2), Fab and Fd fragments reacted with antigen and remained in the circulation as complexes which were eliminated at the same rate as the antigen. Fab hybrids containing a specific Fd fragment and a nonspecific L chain similarly reacted with antigen and remained in the circulation complexed to antigen. In contrast, L chains and Fab hybrids containing a specific L chain and a nonspecific Fd fragment did not react with antigen in vivo and were rapidly eliminated in both presence and absence of antigen. H chains remained in the circulation of rabbits in the absence of antigen, however, in the presence of antigen, more H chains which formed complexes with antigen remained in the intravascular space and were rapidly eliminated when the immune elimination of the antigen by the host occurred. Nonspecific H chains were rapidly eliminated from the circulaion of guinea pigs, whereas specific H chains remained in the circulation with the antigen. F (ab')(2) fragments formed complexes with antigen near antibody equivalence and in antibody excess which were rapidly eliminated, however, less effectively than complexes formed near antibody equivalence with intact gammaG. Complexes formed in antibody excess between Fab fragments and H chains remained in the circulation at all concentrations studied and were eliminated at the rate of antigen. The role of the Fc fragment in the immune elimination of antigen-antibody complexes is discussed. PMID- 4161310 TI - Studies on human antibodies. IV. Purification and properties of anti-A and anti-B obtained by absorption and elution from insoluble blood group substances. AB - Insoluble blood group substances prepared by copolymerization of soluble blood group substances with N-carboxy-L-leucine anhydride were used to absorb blood group antibodies from two human, high-titered anti-A sera. After the absorbants were washed free of nonspecific serum proteins, blood group antibodies were eluted either with pH 3.62 acetate buffer, or at neutral pH with monosaccharide haptens of the A or B antigenic determinants (N-acetyl-D-galactosamine or D galactose respectively). The purified anti-A antibodies were characterized, immunoelectrophoretically, as gammaM-, gammaA-, and gammaG-immunoglobulins. These were further separated into gammaM- and gammaG-fractions by gel filtration or density gradient centrifugation. Both gammaM- and one of the two gammaG-antibody fractions contained K and L light chain determinants; the remaining gammaG fraction was comprised, almost totally, of type K molecules. Precipitability of the purified anti-A immunoglobulins by blood group A substance varied from 43 to 89%. The agglutinating activity per unit N of the isolated gammaG-anti-A was found to equal, in one case, and to exceed, in the second, that of the gammaM antibodies from the same individuals. The marked differences between gammaM- and gammaG-antibody fractions in quantitative hapten inhibition studies were interpreted to mean that the antibody-combining site of the isolated eluted gammaG-anti-A was significantly larger than that of the eluted gammaM-anti-A. Whether these data connote differences in combining site size between entire immunoglobulin classes in an individual serum or simply reflect the properties of highly selected antibody populations cannot be stated at present. PMID- 4161312 TI - Studies on immunoglobulins of Nigerians. II. Immunoglobulins and malarial infection in Nigerians. PMID- 4161313 TI - Studies on immunoglobulins of Nigerians. I. The immunoglobulin levels of a Nigerian population. PMID- 4161314 TI - [Nomenclature of genetic factors supported by human immune globulins]. PMID- 4161315 TI - [On some cardiovascular effects of an indenopyrimidine derivative in rats]. PMID- 4161316 TI - Relations between EEG phenomena and potentials of single cortical cells. II. Spontaneous and convulsoid activity. PMID- 4161318 TI - Stable changes in the pattern of the recruiting response associated with a well established conditioned reflex. PMID- 4161317 TI - Relations between EEG phenomena and potentials of single cortical cells. I. Evoked responses after thalamic and erpicortical stimulation. PMID- 4161319 TI - Thalamic spreading depression in the rat. PMID- 4161320 TI - Electroencephalography in subjects sixty years and over. PMID- 4161321 TI - A neurophysiological comparison of alpha-chloralose with gamma-hydroxybutyrate in cats. PMID- 4161322 TI - A power booster for stimulus isolation units. PMID- 4161323 TI - An automatic drive for micro-electrodes. PMID- 4161324 TI - Abnormal lymphocytes in schizophrenia. PMID- 4161326 TI - [Intractable pain in cancer. Combined neurosurgery and chemotherapy]. PMID- 4161325 TI - Investigations into the mechanism of electroshock in the rat. II. Effect of electrical stimulation on the capillary endothelium and on hemodynamic conditions in histamine and serotonin-depleted rats. PMID- 4161327 TI - [Experimental hypothyroidism. II. Synthetic antithyroid drugs]. PMID- 4161328 TI - [Expulsion of intrathyroid iodine]. PMID- 4161329 TI - Thymic lymphatics and the cellular localization of gamma globulin in the guinea pig thymus. PMID- 4161330 TI - Damage to proteins, enzymes, and amino acids by peroxidizing lipids. PMID- 4161332 TI - [The pathology of galea capitis. I. Diagnosis and coloured preparation of persistent acrosome]. PMID- 4161331 TI - Size classes of soluble liver macromolecules. PMID- 4161333 TI - [Preservation of lipids with techniques used in electron microscopy]. PMID- 4161334 TI - Spectroscopic and staining studies of the ripening and overripening of aluminum hematoxylins. PMID- 4161335 TI - A silver staining reaction for chromosomes and nuclei. PMID- 4161336 TI - [Studies on the causes of non-specific stains in immunofluorescence]. PMID- 4161337 TI - [Atheroma and synthetic heparinoids]. PMID- 4161338 TI - [Our experiences in the treatment of patients with pulmonary tuberculosis and asthma with Histaglobine]. PMID- 4161339 TI - [Further observations of the finer innervation of the larynx]. PMID- 4161340 TI - [Current advantage of the use of gamma globulins in pediatrics]. PMID- 4161341 TI - A colony of actinomyces-like organisms in a periapical granuloma. PMID- 4161342 TI - [Therapy of thyrotoxic crisis]. PMID- 4161343 TI - Heterologous transplantation with Kiel bone. An experimental and clinical study. PMID- 4161344 TI - An unusual late complication of pulmonary artery banding. PMID- 4161345 TI - [Treatment of internal lesions suffered in sports with Lasonil]. PMID- 4161346 TI - Physiochemical properties of reaginic antibody. II. Characteristic properties of reaginic antibody different from human gamma-A-isohemagglutinin and gamma-D globulin. PMID- 4161347 TI - [Intramammary lymphnodes of the milk gland in cattle. II. Microscopic and anatomic conditions]. PMID- 4161348 TI - [Light and electron microscopic investigations of Paneth's cells in the jejunum of the mouse with special attention to their granules]. PMID- 4161349 TI - [Contributions to the morphology and histochemistry of human major vestibular glands]. PMID- 4161350 TI - [Case of Addison's disease associated with hyperthyroidism]. PMID- 4161351 TI - The radiotherapy of carcinoma of the oesophagus and post cricoid region in south east Scotland. PMID- 4161352 TI - The effect of thyroid hormone and an antithyroid drug on the startle response of the rat. PMID- 4161353 TI - [Chemical and physical changes of proteins by beta rays]. PMID- 4161354 TI - Whipple's disease. PMID- 4161355 TI - Nasal decongestants in otorhinolaryngology. PMID- 4161356 TI - Physiologic evidence concerning the re-entry hypothesis for ectopic beats. PMID- 4161357 TI - Infectious mononucleosis. Some observations on the cellular localization of immune globulin synthesis. PMID- 4161358 TI - [On the method of histochemical detection of ketosteroids in the cortical substance of the adrenal]. PMID- 4161359 TI - The diagnostic value of premature beats. PMID- 4161361 TI - Effect of curarisation on breath-holding time. PMID- 4161360 TI - [Artificial lymph node thesaurismosis following polyvinylpyrrolidone]. PMID- 4161363 TI - [Treatment of neurotrophic rheumatism of the upper limb]. PMID- 4161362 TI - Iodine-125-labelled L chains of human blood group antibodies. PMID- 4161364 TI - [Diagnosis of rupture of the amnio-chorial sac by means of the cyto-morphologic method using Nile blue sulfate]. PMID- 4161365 TI - [On the small hyperchromatic nuclei of medulloblastomas]. PMID- 4161366 TI - [Immunoelectrophoretic research on the blood and fragments of the auricle of subjects with mitral stenosis]. PMID- 4161367 TI - Active anaphylactic reaction in mouse peritoneal mast cells in vitro. PMID- 4161368 TI - [Voluminous abdominal mass, hyperazothemia. (Clinico-pathological conference)]. PMID- 4161369 TI - [Quantitative studies on systemic anaphylactic shock in guinea pigs]. PMID- 4161370 TI - [On the behavior of actinomycins in aqueous solutions]. PMID- 4161371 TI - [On the structure of the actinomycin-desoxyguanosine complex]. PMID- 4161372 TI - [The role of histamine in allergic processes]. PMID- 4161373 TI - [C-reactive protein, rheumatoid factor and gamma globulin in the blood serum and synovial fluid in patients with joint diseases]. PMID- 4161374 TI - [A few remarks on the contribution "Limitations of urologic diagnosis" by Prof. Dr. E. R. Welcker]. PMID- 4161375 TI - Diagnosis and results of surgery in renovascular hypertension. PMID- 4161376 TI - Serum-free-fatty-acids after acute myocardial infarction and cerebral vascular occlusion. PMID- 4161377 TI - Hypoglycemia in children with acute diarrhoea. PMID- 4161378 TI - Incidence of a positive direct coombs test in patients on alpha-methyldopa. PMID- 4161379 TI - Autoimmune haemolytic anaemia associated with alpha-methyldopa therapy. PMID- 4161380 TI - Treatment of endotoxic shock with isoprenaline. PMID- 4161381 TI - Functional compensation after small-bowel resection in man. Demonstration by direct measurement. PMID- 4161382 TI - An application of the serological recognition of transplantation antigens on leucocytes. PMID- 4161383 TI - Beryllium poisoning. PMID- 4161384 TI - Protein deficiencies and calorie deficiencies. PMID- 4161385 TI - [Fluorescence microscopy of precancerous conditions of the mouth with the aid of acridine orange staining]. PMID- 4161386 TI - [Acridine orange-chromium fluoride and cytochemical control studies of carcinomas in cytological smear preparations]. PMID- 4161387 TI - [On the granular neuroma (so-called myoblastic myoma)]. PMID- 4161389 TI - Chemical evaluation of conformational differences in native and chemically modified proteins. PMID- 4161390 TI - The effect of organic solvents on rabbit antibody. PMID- 4161391 TI - [Contribution to the study of the electrophoretic pattern in the postoperative period of splenectomized patients]. PMID- 4161392 TI - Spontaneous peritonitis in cirrhosis of the liver. PMID- 4161388 TI - [New findings on the innervation of the vascular system. (Investigations with application of the osmium-zinc iodide method on the aorta, thyroid glands and iris vessels of the rabbit and on the corpus cavernosum penis of the white mouse)]. PMID- 4161393 TI - [Metabolism of plasma albumin in the light of isotopic investigations]. PMID- 4161394 TI - Ultraviolet reactivation of a bacteriophage containing a single-stranded deoxyribonucleic acid as a genetic element. PMID- 4161395 TI - Interaction between poliovirus and immunoglobulins. 3. The effect of cleavage products of rabbit gamma-G-globulin on infectivity and distribution of virus in polymer phase systems. PMID- 4161396 TI - Further studies on the specificity of presumed immune associations of myasthenia gravis and consideration of possible pathogenic implications. PMID- 4161397 TI - Direct fluorescent antibody studies of gamma globulin localization in muscle of patients with myasthenia gravis. PMID- 4161398 TI - Ultrastructural localization of gamma globulin binding to skeletal muscle. PMID- 4161399 TI - Studies in myasthenia gravis: demonstration of presence of immunofluorescence in serums correlated with clinical findings. PMID- 4161400 TI - Does myasthenic serum bind to the neuromuscular junction? PMID- 4161402 TI - [Symbolism. 1]. PMID- 4161401 TI - Occurrence of two different rheumatoid factors reacting with immune and normal rabbit gamma-globulins. PMID- 4161403 TI - [Symbolism. 2]. PMID- 4161404 TI - 1966 annual award. Presentation address. PMID- 4161405 TI - [Display cases in a Swedish dental clinic for children]. PMID- 4161406 TI - Unit signs of visual cortex modulation by the lateral geniculate body. PMID- 4161407 TI - Changes in visual recovery functions produced by temporal lobe stimulation in monkeys. PMID- 4161408 TI - Steady potential correlates of intracranial reinforcement. PMID- 4161409 TI - The natural history of isolated ventricular septal defects in infancy. Indication for palliative, surgical treatment. PMID- 4161410 TI - Trypsin stabilizers in human serum. The role of alpha-2-macroglobulin. PMID- 4161411 TI - [On the alleged acidophilia of parietal cells]. PMID- 4161413 TI - [Rapid procedure for staining of nuclei of yeasts and molds (HCl-Boroviczeny stain)]. PMID- 4161412 TI - The staining behavior of oocyte cytoplasm with the alcoholic Feulgen variant and with methyl green. PMID- 4161414 TI - Prosatic massage and the plasma acid phosphatase level. PMID- 4161415 TI - The effect of epsilon aminocaproic acid on the blood loss after retropubic prostatectomy. PMID- 4161416 TI - Molecular genetics of avian proteins. VI. Evolutionary implications of blood proteins of eleven species of geese. PMID- 4161417 TI - [Studies on examination methods with dyes for some biochemical functions of the cornea. Fluorescein test, methylene blue test and Evans blue test]. PMID- 4161418 TI - Acute rheumatic fever and carditis in older adults. PMID- 4161419 TI - The simple assessment of selectivity in heavy proteinuria. PMID- 4161420 TI - Effect of antisecretory drugs on gastric hypersecretion in endocrine-adenoma syndromes. PMID- 4161421 TI - Effects of dextran 40 on postoperative renal haemodynamics. PMID- 4161422 TI - Effect of a small decrease in blood-glucose on plasma-growth-hormone and urinary excretion of catecholamines in man. PMID- 4161423 TI - The value of diuretics in respiratory failure. PMID- 4161424 TI - Antibodies to cytoplasm of ova. PMID- 4161425 TI - Dicoumarol-induced diphenylhydantoin intoxication. PMID- 4161426 TI - Anaesthesia during hypotensive therapy. PMID- 4161428 TI - The medical officer of health. PMID- 4161427 TI - Exchange transfusion in anaemia. PMID- 4161429 TI - Autoimmunity to inflammatory exudates. PMID- 4161430 TI - Hypertension and limb lengthening. PMID- 4161431 TI - Towards the organisation of biochemistry in the general hospital. PMID- 4161432 TI - Tetracyclines and the teeth. PMID- 4161433 TI - Drug addiction. PMID- 4161434 TI - [Specific gamma- and beta-globulin activity of the placental blood to adeno- and influenza viruses]. PMID- 4161435 TI - [Effect of the passive immunization on the sensitizing activity of Bordetella pertussis. I. Increase of sensitivity to repeated homologous antigen administrations]. PMID- 4161436 TI - [Studies on the prevention of serum hepatitis]. PMID- 4161437 TI - [T loop in ventricular extrasystole]. PMID- 4161438 TI - Clinical evaluation of the blood smear. PMID- 4161439 TI - A clinical and cytogenetical study of three patients with male phenotype and apparent XX sex chromosome constitution. PMID- 4161441 TI - Immunological significance of the morphological changes in lymph nodes draining breast cancer. PMID- 4161440 TI - The N- and c-terminal amino acid sequences of the heavy chain from a pathological human immunoglobulin IgG. AB - The heavy chain of a pathological human immunoglobulin IgG and also the Fd fragment have been isolated. No free alpha-amino group was present on either and the N-terminal sequence of both has been identified as pyrrolid-2-one-5 carbonylvalylthreonine. Splitting at the four methionine residues of the heavy chain with cyanogen bromide gave five fractions. The fraction from the C-terminal end of the chain was isolated in high yield and the amino acid sequence was: His Glu-Ala-Leu-His-Asp(NH(2))-His-Tyr-Thr-Glu(NH(2))-Lys-Ser-Leu-Ser-Leu-Ser-Pro-Gly These results give strong support to the view that the heavy chain of immunoglobulin is a single peptide chain. PMID- 4161442 TI - Anaphylactic tests for tumour antigen in transplantable animal tumours. PMID- 4161443 TI - [Adaptation of the Gomori and the azo-dye staining technics for alkaline phosphatase in the evaluation of vaginal smears]. PMID- 4161444 TI - A combined staining rack and slide washer. PMID- 4161445 TI - Thrombohemorrhagic lesions induced by combined treatment with rare earth metals and epinephrine. PMID- 4161446 TI - The value of the plasma protein-bound iodine estimation in the diagnosis of primary myxoedema and thyrotoxicosis. PMID- 4161447 TI - [Anti-D gamma globulins in the prevention of hemolytic disease of the newborn]. PMID- 4161448 TI - [Comparison of the protein spectra obtained from the transparent and nontransparent human corneal grafts in the cornea of the rabbit]. PMID- 4161449 TI - [Structure of immune globulin paraprotein and globulin in Franklin's syndrome]. PMID- 4161450 TI - [On the elastic fiber framework of the medulla of the human adrenal glands]. PMID- 4161451 TI - [Studies on synapses of the peripheral vegetative nervous system. V. Additional observations on the ending systems of postganglionic nerve fibers]. PMID- 4161452 TI - A brief look at the management of hyperthyroidism. PMID- 4161453 TI - Ageing of the human temporo mandibular disk with special reference to the occurrence of cartilaginous cells. PMID- 4161454 TI - [Pain and cancer]. PMID- 4161455 TI - Insulin antibodies in pregnant guinea pigs and in their offspring. PMID- 4161456 TI - Placental transfer of insulin-131-I in guinea pigs immunized against insulin. PMID- 4161457 TI - The failure of gamma globulin as a prophylactic agent in meningococcal disease. PMID- 4161458 TI - The synthesis of actinomycin analogues. II. Actinocylgramicidin S. PMID- 4161459 TI - A clinical stain for use in selecting biopsy sites in patients with vulvar disease. PMID- 4161460 TI - Evaluation of a new sequential contraceptive agent. PMID- 4161461 TI - Endometrial morphology after sequential medication with mestranol and chlormadinone. PMID- 4161462 TI - The feed-back mechanism in immunoglobulin synthesis. PMID- 4161463 TI - Isolation of a reaginic antibody fraction with properties of gamma-g-globulin. PMID- 4161464 TI - Separation of trypsin inhibitors of human plasma on DEAE-cellulose. PMID- 4161465 TI - Isoimmunization with Human gamma-G immunoglobulins. PMID- 4161466 TI - Quantitative studies on gamma-2 anti-dinitrophenyl antibodies. PMID- 4161467 TI - Comparative development of pheasant and chick embryo sera. PMID- 4161469 TI - Amyloid staining with Thioflavine T in dermatopathology. PMID- 4161468 TI - Polarographic characteristics of human albumin, gamma globulin, ceruloplasmin and transferrin. PMID- 4161470 TI - The immunoglobulins. PMID- 4161471 TI - Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. PMID- 4161472 TI - Immunoglobulins. PMID- 4161473 TI - A comparison of the labile disulfide bonds of rabbit gamma-G-immunoglobulin fragments. PMID- 4161474 TI - The metabolism of human gammaglobulin. PMID- 4161475 TI - [Study on pretreated struma]. PMID- 4161476 TI - Examination for tubercle bacili by fluorescence microscopy. PMID- 4161477 TI - The origin of yeasts from sputum. PMID- 4161478 TI - Azophloxine GA, a selective stain for light and fluorescence microscopy of myoepithelial cells. PMID- 4161479 TI - Fixation and staining of fungus hyphae and host plant root tissues for electron microscopy. PMID- 4161480 TI - A pollen grain squash technique for Saccharum and related genera. PMID- 4161481 TI - Calcium in cells of fresh bone stained with glyoxal bis(2-hydroxyanil). PMID- 4161482 TI - Two-color fluorescent labeling of mineralizing tissues with tetracycline and 2,4 bis[N,N'-di-(carbomethyl)aminomethyl] fluorescein. PMID- 4161483 TI - Flazo orange for masking of auto and nonspecific fluorescence of leukocytes and tissue cells. PMID- 4161484 TI - Dysthyroid exophthalmos. Palliation by lateral orbital decompression. PMID- 4161485 TI - Mucopolysaccharide staining in experimental corneal edema. PMID- 4161486 TI - Modification of the homograft reaction in corneal transplantation. Further studies. PMID- 4161487 TI - Liberal use of antibiotics and its effect in neonatal staphylococcal infection, with particular reference to erythromycin. PMID- 4161488 TI - Immune response of man to inoculation with Plasmodium cynomolgi and challenge with P. vivax. PMID- 4161489 TI - Use of silver-nitrate solutions in maintenance of air hygiene in a burns unit. PMID- 4161490 TI - Bacteriuria in old age. PMID- 4161491 TI - Toxic diffuse goitre in monozygotic twins. PMID- 4161492 TI - The normal thyroid scan. PMID- 4161493 TI - Effects of micturition on leg reflexes. PMID- 4161494 TI - pH studies in human malignant tumours. PMID- 4161495 TI - Experimental autoimmune thymitis. An animal model of human myasthenia gravis. PMID- 4161496 TI - Coaxial flow-guided catheterization of the pulmonary artery in transposition of the great arteries. PMID- 4161497 TI - Erythropoiesis in chronic renal disease. PMID- 4161498 TI - Renin and hypertension. PMID- 4161499 TI - Hand-drill attachment for simplifying wire suturing of the sternum. PMID- 4161500 TI - Parental deprivation and mental health. PMID- 4161501 TI - Arthrodesis, arthroplasty, or abduction osteotomy? PMID- 4161502 TI - Obesity in childhood. PMID- 4161503 TI - Fluorescent-antibody techniques in the diagnosis of syphilis. PMID- 4161505 TI - Aetiology of reticuloses. PMID- 4161504 TI - Shortage of people. PMID- 4161506 TI - Cleanliness. PMID- 4161507 TI - Dopamine storage and parkinsonism. PMID- 4161508 TI - Universities and government. The constant dialogue. PMID- 4161509 TI - Dietary factors associated with death-rates from certain neoplasms in man. PMID- 4161510 TI - A safer system of supply and storage of medicines in hospitals. PMID- 4161512 TI - Laboratory suggestion. A simple staining unit for coverslips. PMID- 4161511 TI - Vehicle exhausts in relation to public health. PMID- 4161513 TI - Presence of large numbers of plasma cells containing IgD in the rectal mucosa of a patient with ulcerative colitis. PMID- 4161514 TI - Histochemical studies on acid mucopolysaccharides. I. On some new methods and differentiation in tissue sections. PMID- 4161515 TI - [Palliative anastomoses in infants with Fallot's tetralogy. (Apropos of 158 cases)]. PMID- 4161516 TI - [Pallitive surgery in tetralogy of Fallot. Value of prosthetic bridging]. PMID- 4161517 TI - [On the etiology and prevention of endemic goiter. II. Thyroid function in subjects residing in an endemic area]. PMID- 4161518 TI - [Arthropathy of the knee joint in congenital analgia]. PMID- 4161519 TI - Low-temperature spectropolarimetry of protein solutions and the study of fast conformation changes in their molecules. PMID- 4161520 TI - Determination of gamma globulin in the cerebrospinal fluid by quantitative chromatography. PMID- 4161521 TI - Immunoelectrophoretic studies in patients with cryofibrinogenemia. PMID- 4161522 TI - Simple assessment of thyroid activity: the T3 resin sponge uptake test. PMID- 4161523 TI - A scheme of care during pregnancy. PMID- 4161524 TI - [Results of treatment in combined finger deformities]. PMID- 4161526 TI - Filling skeletal defects with thin plates of homogenous bone by the "faggot" method. PMID- 4161525 TI - Clinical experience in homotransplantation of thyroid and parathyroid glands on vascular stumps. PMID- 4161527 TI - [The Thallwitz principles in the treatment of cleft lip, palate and jaw]. PMID- 4161528 TI - [On the terminology of cleft lips, jaws and palates]. PMID- 4161529 TI - Congenital malformations of the auricle and their reconstruction by a new method. PMID- 4161530 TI - Method of covering gaping defects in the walls of the pharynx and cervical section of oesophagus after surgical removal of larynx. PMID- 4161531 TI - Severe and extensive loss of skin on the limbs. PMID- 4161532 TI - Staining of sectioned leptospirae with heavy metals. PMID- 4161533 TI - Immunocytes and immunoglobulins. PMID- 4161534 TI - Injection of rabbit anti-rat serum into rats presensitized with rabbit serum. PMID- 4161535 TI - The distribution of immunoglobulin-containing cells along the human gastrointestinal tract. PMID- 4161536 TI - Electrophoretic study of human isoamylases. A new saccharogenic staining method and preliminary results. PMID- 4161537 TI - "We are here to learn from one another". PMID- 4161538 TI - A challenge to APCA. PMID- 4161539 TI - The seasonal, weekly, and daily cycles of atmospheric smoke content in central Montreal. PMID- 4161540 TI - Electric car system introduced. PMID- 4161541 TI - Symposium on current trends in peripheral vascular surgery. Acute venous occlusion. PMID- 4161542 TI - [The treatment of Sudeck's dystrophy with neuroplegics]. PMID- 4161543 TI - Some serum protein polymorphisms in Kalahari bushmen and Bantu: gamma globulins, haptoglobins, and transferrins. PMID- 4161544 TI - Posterior root canal therapy. I. PMID- 4161545 TI - [Systemic scleroderma associated with progressive chronic polyarthritis and a positive finding of typical LE cells]. PMID- 4161546 TI - [Study on red blood cell and resin uptake of 131-I labeled 3,5,3'-L triiodothyronine in thyroid diseases]. PMID- 4161547 TI - The plasma inorganic iodine concentration in thyrotoxicosis. PMID- 4161548 TI - Serum immunoglobulins in rheumatoid arthritis. PMID- 4161549 TI - [Some clinical experiences of "Eviprostat" in prostatic hypertrophy]. PMID- 4161550 TI - [A modification of the method of beta-aminoisobutyric acid determination in the urine and tissues of animals]. PMID- 4161551 TI - [Significance of sialic acid and erythrocyte sedimentation rate in the diagnosis of surgical diseases]. PMID- 4161552 TI - [On the diphenylamine method of quantitative determination of sialic acids]. PMID- 4161553 TI - [Association of electrophoresis and chromatography for the investigation of amino acids in hydrolysates]. PMID- 4161554 TI - [The Sudan test and its value for the determination of the stability of the bonds between proteins and lipids of blood serum]. PMID- 4161555 TI - [On causes on inconsistency in the determination of glutamic-oxaloacetic transaminase in the serum]. PMID- 4161556 TI - [Cytological diagnosis of intraocular tumors]. PMID- 4161557 TI - [Use of cytochemical methods in the investigation of smears from the cervix uteri]. PMID- 4161558 TI - [On the problem of the cytological diagnosis of appendicitis]. PMID- 4161559 TI - [Diagnostic value of cytological investigation of the urine and kidney tumor punctates in children]. PMID- 4161560 TI - [On the participation of disintegrated erythrocytes in the process of fibrinolysis]. PMID- 4161561 TI - [Method of the quantitative determination of plasminogen and plasmin inhibitors in the blood serum]. PMID- 4161562 TI - [The method of in vivo fluorochromization of microorganisms in an agar nutritive chamber]. PMID- 4161563 TI - [On the method of determination of enteropathogenic Escherichia coli]. PMID- 4161564 TI - [Tricarbohydrate medium with urine for the investigation of enterobacteriae]. PMID- 4161565 TI - [Trial of the use of Olkenitski's medium for the study of bacteria of the Enterobacteriaceae group]. PMID- 4161566 TI - [Complex analysis of feces in gastrointestinal disorders of obscure etiology]. PMID- 4161567 TI - [Use of the universal "FU" fluoroscope in bacteriological work]. PMID- 4161568 TI - [Use of a wide-neck thermos for the inactivation of serums]. PMID- 4161569 TI - [Filtering device]. PMID- 4161570 TI - [Automatic microburet for amperometric titration]. PMID- 4161571 TI - [A modification of the device for obtaining an ultrafilterable fraction of calcium from the blood plasma]. PMID- 4161572 TI - [Tungsten aperture and condenser diaphragms in electron microscopy]. PMID- 4161573 TI - [Therapeutic use of antibiotics and gamma globulin for osteomyelitis]. PMID- 4161574 TI - Synergic effect of naturally occurring goitrogens on the thyroid gland in rats. PMID- 4161575 TI - The effect of thyrotropic hormone in vivo on autoiodoproteolysis of 127-I thyroglobulin in vitro. PMID- 4161576 TI - [Electrophoretic and immunoelectrophoretic studies of protein fractions of the blood serum in infants]. PMID- 4161577 TI - [Allotypes of serum immunoglobulins in systemic lupus erythematosus]. PMID- 4161578 TI - Isoniazid plus thioacetazone compared with two regimens of isoniazid plus PAS in the domiciliary treatment of pulmonary tuberculosis in South Indian patients. AB - Previous reports from the Tuberculosis Chemotherapy Centre, Madras, have established that ambulatory treatment of pulmonary tuberculosis with a standard daily regimen of isoniazid plus PAS for one year yields satisfactory results. However, this regimen may be unsuitable for large-scale use in many developing countries, because PAS is expensive, bulky and unpleasant to take, and has poor keeping qualities, especially in tropical countries. It might be possible to overcome these disadvantages, by substituting for the PAS a drug which is equally effective but less expensive and more acceptable, or by reducing the daily dosage of PAS and the period for which it is prescribed.This paper presents the results over a 12-month period of a controlled comparison of (a) the standard regimen of isoniazid (average 4.5 mg/kg body-weight) plus sodium PAS (average 0.22 g/kg), daily in two divided doses; (b) a regimen of isoniazid (average 6.9 mg/kg) plus thioacetazone (average 3.4 mg/kg), daily in one dose; and (c) a 2-phase regimen of isoniazid (average 5.5 mg/kg) plus sodium PAS (average 0.17 g/kg), daily in one dose for 6 months, followed by isoniazid alone (average 6.8 mg/kg), daily in one dose for the second 6 months. The regimen of isoniazid plus thioacetazone was found to be therapeutically as effective as the standard regimen of isoniazid plus PAS; however, it was associated with a higher incidence of minor side effects, and three cases of exfoliative dermatitis. The 2-phase regimen of isoniazid plus PAS followed by isoniazid alone was less effective.These findings are encouraging for the large-scale use in developing countries of the relatively inexpensive regimen of isoniazid plus thioacetazone; however, any such step should be preceded by carefully planned studies to investigate, under local conditions, the toxicity and the efficacy of the regimen. PMID- 4161579 TI - [Considerations on the variability of the morphology of bigeminal ventricular extrasystoles, in relation to the pathogenetic mechanism of extrasystoles]. PMID- 4161580 TI - [Pelvic lymph node metastases and a method of preoperative lymph node staining in surgery of cervical cancer]. PMID- 4161581 TI - The chemical and histochemical properties of alcian blue. IV. Further studies on the methods for the identification of acid glycosaminoglycans. PMID- 4161582 TI - Histone specificity revealed by ammoniacal silver staining. PMID- 4161583 TI - New approaches to tetanus prophylaxis. PMID- 4161584 TI - Patterns of hormonal release after glucose, protein, and glucose plus protein. PMID- 4161585 TI - Incidence and epidemicity of Down's syndrome. PMID- 4161586 TI - Aortic-valve replacement. PMID- 4161587 TI - The preparation of aortic-valve homografts. PMID- 4161588 TI - Fatty foods and dyspersia. PMID- 4161589 TI - Vesico-uretheral reflux and asymptomatic bacteriuria in the puerperium. PMID- 4161590 TI - Lymphocyte cultures in drug hypersensitivity. PMID- 4161591 TI - The use of double-wrapped packs to reduce contamination of the sterile contents during extraction. PMID- 4161592 TI - Effect of a xanthine-oxidase inhibitor (allopurinol) on radioiron absorption in man. PMID- 4161593 TI - Hyperphagia induced by ventricular pressure and pentobarbitone in normal and hypothalmic obese rats. PMID- 4161594 TI - Clubbing of the fingers and hypertropic osteoarthropathy in pregnancy. PMID- 4161595 TI - X-Y chromosomal interchange in the aetiology of true hermaphroditism and of XX Klinefelter's syndrome. PMID- 4161596 TI - A simple technique for continuous gastric aspiration. PMID- 4161597 TI - Social security. PMID- 4161598 TI - Gastric ulcer and gastritis. PMID- 4161599 TI - Crumbling edifice. PMID- 4161600 TI - A fresh look at protein-calorie malnutrition. PMID- 4161601 TI - [On the start of neurosecretion and secretion of the subcommisural organ in lamprey embryos]. PMID- 4161602 TI - The second International Standard for Dihydrostreptomycin. AB - The National Institute for Medical Research, London, was requested by the WHO Expert Committee on Biological Standardization to establish a second International Standard for Dihydrostreptomycin, since stocks of the first International Standard were depleted. A batch of 500 g of dihydrostreptomycin sulfate obtained in 1961 was distributed into ampoules in 200-mg amounts and dried in vacuo; the ampoules were then filled with dried nitrogen and sealed. The proposed replacement material has been assayed biologically in terms of the first International Standard in seven laboratories in six countries by means of both plate-diffusion and turbidimetric assays.Significant heterogeneity of the potencies obtained by the different laboratories was revealed by statistical analysis; this heterogeneity might be caused by slight differences in the content of streptomycin of the two samples. The material has been established as the Second International Standard for Dihydrostreptomycin with a defined potency of 820 IU/mg. The International Unit of Dihydrostreptomycin is defined as the activity of 0.001219 mg of the Second International Standard for Dihydrostreptomycin. PMID- 4161603 TI - Some histochemical effects in the rat uterus submitted to ionophoresis in vivo. PMID- 4161604 TI - Further researches on transplantable tumours subjected to ionophoresis in vivo. PMID- 4161605 TI - [Clinical use of chloramphenicol with gamma-globulin (Chlorabulin) for infections in children]. PMID- 4161606 TI - Myringotomy in acute otitis media. A controlled study. PMID- 4161607 TI - The pigmented hive. PMID- 4161608 TI - [Immunological studies on skin-sensitizing antibodies. 1. Its relation to immunoglobulins]. PMID- 4161609 TI - Transfusion-asociated viral hepatitis. PMID- 4161610 TI - Effects of rheumatoid factor on complement levels in vivo. PMID- 4161611 TI - Incidence and prediction of ischaemic heart-disease in London busmen. PMID- 4161612 TI - A follow-up study of infants born to mothers with oestriol excretion during pregnancy. PMID- 4161613 TI - Effect of abdominal operation on glucose tolerance and serum levels of insulin, growth hormone, and hydrocortisone. PMID- 4161614 TI - Frequency of autoantibodies in patients with chromatin-positive Klinefelter's syndrome and their parents. PMID- 4161615 TI - Effect of long-term corticosteroids and corticotrophin on the growth of children. PMID- 4161616 TI - The role of erythrasma in pruritus ani. PMID- 4161617 TI - Gastrostomy in neonatal respiratory failure. PMID- 4161618 TI - Treatment by local application of insulin of an infected wound in a diabetic. PMID- 4161620 TI - Sands of planning. PMID- 4161619 TI - Assessment of lung function. PMID- 4161621 TI - Laboratory services for the general practitioner. PMID- 4161622 TI - Insecticide residue in foods subjected to aerosols under simulated warehouse conditions. PMID- 4161623 TI - Anti-gamma-globulin factors in visceral larva migrans. PMID- 4161624 TI - The distribution of antigenic and nonantigenic compounds within draining lymph nodes. PMID- 4161625 TI - [Use of heparinoid-hyaluronidase ointment in practice]. PMID- 4161627 TI - Comments on immunization. PMID- 4161626 TI - Active and passive immunization of chimpanzees infected with West African and Southeast Asian strains of Plasmodium falciparum. PMID- 4161628 TI - [Mechanism of LE cell production]. PMID- 4161629 TI - Cytotoxic antibodies against leucocytes. PMID- 4161630 TI - Radiological diagnosis of disaccharidase deficiency. PMID- 4161631 TI - Fibrinolytic response to oral glucose. PMID- 4161632 TI - [Encephalitis following smallpox vaccination]. PMID- 4161633 TI - I-131 metabolism in whole and sliced rat thyroid lobes. PMID- 4161634 TI - Manifestations of immunologic unresponsiveness in Hodgkin's disease. PMID- 4161635 TI - Lymphoid malignancy and development, differentiation, and function of the lymphoreticular system. PMID- 4161636 TI - [Protein bound iodine (PBI) in the evaluation of thyroid activity in children with dwarfism and low-stature]. PMID- 4161637 TI - Late results of medical and surgical treatment of bleeding peptic ulcer. PMID- 4161639 TI - Treatment of idiopathic secondary amenorrhoea with single injections of follicle stimulating hormone and chorionic gonadotrophin. PMID- 4161638 TI - Hashimoto's disease and encephalopathy. PMID- 4161640 TI - Abdominal arterial murmurs in liver disease. PMID- 4161641 TI - Hormone-excretion patterns in patients with dysmenorrhoea. PMID- 4161642 TI - Blood-levels of hydrocortisone, transaminases, and cholesterol after myocardial infarction. PMID- 4161643 TI - Adrenergic blockade and the eye signs of thyrotoxicosis. PMID- 4161644 TI - Electron microscopy in the rapid diagnosis of smallpox. PMID- 4161646 TI - The organisation of pharmacology. PMID- 4161645 TI - Antidiuretic effect of diguanides. PMID- 4161647 TI - Dental caries and the comforter. PMID- 4161648 TI - Towards a numerate profession. PMID- 4161650 TI - Our problem too. PMID- 4161649 TI - Vitamin-A deficiency and blindness. PMID- 4161651 TI - Thrombophlebitis and pregnancy. PMID- 4161653 TI - The bleeding ulcer. PMID- 4161652 TI - "Only connect"... PMID- 4161654 TI - Training as a consultant. PMID- 4161655 TI - Put the child to bed. PMID- 4161656 TI - [Amino acid composition of the alpha-3-protein in the blood serum of non irradiated and irradiated dogs]. PMID- 4161657 TI - Don't tell them...show them. PMID- 4161658 TI - In vitro selection and identification of antibiotic resistant Mycoplasma mutants. PMID- 4161659 TI - Y chromosome and exclusion of paternity. PMID- 4161660 TI - The influence of chronic infection on blood-pressure in New Guinea males. PMID- 4161661 TI - A simple catheter for continuous intravascular sampling. PMID- 4161662 TI - Unsuspected Wilms tumor. Dangers in the conservative therapy of renal trauma. PMID- 4161663 TI - Reaction after administration of macroaggregated albumin for a lung scan. PMID- 4161664 TI - Studies in a hyperthyroid subject after hypophysectomy. PMID- 4161665 TI - The effect of chloral hydrate on bishydroxycoumarin metabolism; a fatal outcome. PMID- 4161666 TI - Alterations in the values or tests of thyroid function in rabbits with immunologically produced thyroiditis. PMID- 4161667 TI - Paediatrics 1984. PMID- 4161668 TI - Inherited thrombocytopenia. PMID- 4161669 TI - Hashimoto's disease. A clinicopathological study with matched controls. Lack of significant associations with other "autoimmune" disorders. PMID- 4161671 TI - Development of "autoimmune processes" in rabbits after neonatal removal of central lymphoid tissue. PMID- 4161670 TI - Intra-arterial cytotoxic therapy and x-ray therapy for cancer of the head and neck. PMID- 4161672 TI - Diabetes insipidus and obsessional neurosis. A syndrome. PMID- 4161673 TI - Effect of desferrioxamine on iron absorption. PMID- 4161674 TI - Contact dermatitis from neomycin and framycetin. PMID- 4161675 TI - Mesenteric embolus treated with low-molecular-weight dextran. PMID- 4161676 TI - Immunoallergic lung purpura treated with azathioprine. PMID- 4161677 TI - Silicone foam resting splints for rheumatoid arthritis. PMID- 4161678 TI - Warning device for oxygen cylinders. PMID- 4161679 TI - The part-time teacher. PMID- 4161680 TI - Tropical neurology. PMID- 4161681 TI - Health of immigrants. PMID- 4161682 TI - Results of respiratory-function tests in miners. PMID- 4161683 TI - Corticosteroids in the acute infections. PMID- 4161684 TI - A psychiatric mother and baby. PMID- 4161685 TI - Autosomal monosomy in a spontaneous abortion. PMID- 4161686 TI - Mongolism and thyroid autoimmunity. PMID- 4161687 TI - Parathion poisoning in Finland. PMID- 4161688 TI - [Endoesophageal intubation of malignant stenosis with Celestin's tube]. PMID- 4161689 TI - [Tanderil in the treatment of Sudeck's syndrome]. PMID- 4161690 TI - [Immunoelectrophoretic patterns of blood serum proteins of patients with gastric cancer]. PMID- 4161691 TI - Partial excision of the vomer in infancy. PMID- 4161692 TI - [Significance and role of anesthesia in the complex rehabilitation of patients with cleft lips, jaws and palates]. PMID- 4161693 TI - Plastic operations of abdominal wall. PMID- 4161694 TI - Observations on the treatment of burns in the tropics. PMID- 4161695 TI - The nomenclature for cleft lip and/or palate. PMID- 4161696 TI - Cleft uvula--a microform of cleft palate. PMID- 4161697 TI - [Experimental research on the value and applicability of various bone transplants in reconstructive jaw and face surgery]. PMID- 4161698 TI - [A case of chronic lymphocytic leukemia with interesting serum protein abnormality (gamma-system abnormality)]. PMID- 4161699 TI - Middle ear mucosa. PMID- 4161700 TI - The present status of the caval-pulmonary anastomosis. PMID- 4161701 TI - Cytoplasmic granules of the corneal stroma cell. PMID- 4161703 TI - [Method of conservation of metachromasia in permanent preparations]. PMID- 4161702 TI - Effect of anabolic hormone on albumin and globulin turnover in aged patients. PMID- 4161704 TI - Study on the effects of carbimazole therapy in heart diseases. PMID- 4161705 TI - [On some rare vulvar and vaginal tumors]. PMID- 4161706 TI - Delayed-type hypersensitivity and the immunology of Hodgkin's disease, with a parallel examination of sarcoidosis. PMID- 4161707 TI - Hashimoto's disease. A search for associated disorders in 170 clinically detected cases. PMID- 4161708 TI - Investigation of the occurrence of dermatophytes on the floor and in the air of indoor environments. PMID- 4161709 TI - [Diseases associated with a myelomatous protein]. PMID- 4161710 TI - Circulating total serum-lipids in healthy and malnourished infants. PMID- 4161712 TI - [Value of the determination of protein-bound iodine in the evaluation of the functional state of the thyroid]. PMID- 4161711 TI - [Differentiation of sensitivity of Pediculus humanus humanus L. to chloroganic insecticides, in relation to physiological and environmental conditions. I. Influence of p,p DDT and gamma hexachlorocyclohexane on sensitivity in Pediculus humanus in relation to sex]. PMID- 4161713 TI - The mucoid cells of the adenohypophysis of the rabbit during pregnancy and lactation. PMID- 4161714 TI - Studies of amniotic membranes. PMID- 4161715 TI - The proteolysis of immunoglobulin G with long-acting thyroid-stimulating activity. AB - 1. Proteolysis of immunoglobulin G with long-acting thyroid-stimulating activity with papain and pepsin shortened the duration of thyroid stimulation in mice prepared for the McKenzie (1958) bioassay. The time-course appeared to be related to molecular size. 2. The activity after proteolysis was recovered solely in the electrophoretically slow F(ab)-fragment. 3. There was no immunological cross reaction between pituitary thyroid-stimulating hormone and the active fragments of the long-acting thyroid stimulator despite their similar behaviour in the bioassay. 4. The implications of these findings are discussed. PMID- 4161716 TI - Recovery of antigenic activity upon reoxidation of completely reduced polyalanyl rabbit immunoglobulin G. PMID- 4161717 TI - Polysaccharides associated with the exterior surface of epithelial cells: kidney, intestine, brain. PMID- 4161718 TI - Long-term arterial-graft patency in relation to platelet adhesiveness, biochemical factors, and anticoagulant therapy. PMID- 4161719 TI - Complement-dependent biological functions in complement deficiency in man. PMID- 4161720 TI - Attempted adoptive immunotherapy of acute leukaemia by leucocyte transfusions. PMID- 4161721 TI - A simple technique for measuring changes in ventilatory response to carbon dioxide. PMID- 4161722 TI - Acid-base status of amniotic fluid during delivery. PMID- 4161723 TI - Pathological changes in the nervous system in severe neonatal hypoglycaemia. PMID- 4161724 TI - The complement system and body defence. PMID- 4161725 TI - Infected meat. PMID- 4161727 TI - Recurrent meningitis. PMID- 4161726 TI - Deep freeze. PMID- 4161728 TI - Crime '65. PMID- 4161729 TI - Pregnancy and drug metabolism. PMID- 4161730 TI - A successful parasite. PMID- 4161731 TI - Closure of umbilical blood vessels. PMID- 4161732 TI - Late-night education. PMID- 4161733 TI - Who goes to alcoholics anonymous? PMID- 4161734 TI - Tetracyclines and the teeth. PMID- 4161735 TI - A. A. O. audio-visual library listing--1966 additions. PMID- 4161736 TI - Genito-urinary problems. PMID- 4161737 TI - Diagrammatic color slides quickly made. A new method from various materials. PMID- 4161738 TI - Pacing on demand in the treatment of atrioventricular conduction-disturbances of the heart. PMID- 4161739 TI - Genetic regulatory mechanisms and carcinogenesis. PMID- 4161740 TI - [Contribution to the differential diagnosis of thyroid gland tumors with inclusion of the radioiodine-and localization test]. PMID- 4161741 TI - Hypercalcemia of thyrotoxicosis. PMID- 4161742 TI - Light-chain disease. An abortive variant of multiple myeloma. PMID- 4161743 TI - Severe diarrhea controlled by gamma globulin in a patient with agammaglobulinemia, amyloidosis, and thymoma. PMID- 4161744 TI - The effect of iodochloro-oxyquinoline and iopanoic acid on the determination of PBI and BEI. PMID- 4161746 TI - A staining pool for mammalian eggs. PMID- 4161745 TI - [The effect of some anticoagulant agents on coronary blood flow]. PMID- 4161748 TI - A syndrome of the neural crest. PMID- 4161747 TI - The vascular pathology of thrombotic thrombocytopenic purpura. An immunohistochemical and ultrastructural study. PMID- 4161749 TI - Fluorescence depolarization. II. The intramolecular relationships of the constituent fragments of gamma-globulin. PMID- 4161750 TI - The negative staining of protein molecules. PMID- 4161751 TI - [Serovaccination against hog cholera: information drawn from the determination of leukopenia and gamma globulin levels]. PMID- 4161752 TI - Runt diseases as a model of immunosuppressive therapy. PMID- 4161753 TI - [On phylogenetics of Gm gammaglobulin polymorphism]. PMID- 4161754 TI - Some physical-chemical properties of chicken gamma-globulins and their pepsin and papain digestion products. PMID- 4161755 TI - On the distribution of rheumatoid factors among the immunoglobulins. PMID- 4161756 TI - On the heterogeneity of the light chains of rabbit antibodies. PMID- 4161757 TI - The Fd' fragment of human gamma-G immunoglobulin. PMID- 4161758 TI - An analogue for negative staining. PMID- 4161759 TI - Properties of a virus-induced RNA polymerase in ascites cells infected with encephalomyocarditis virus. PMID- 4161760 TI - Fluorescent staining techniques in early diagnosis of tissue alterations. PMID- 4161761 TI - Allotypic specificities in pigs. PMID- 4161763 TI - [Prostatic hypertrophy. Dilatation as opposed to transurethral resection- prostatectomy. Follow-up study]. PMID- 4161762 TI - [Prostatic hypertrophy. Deisting's dilation treatment combined with transurethral prostate resection and prostatectomy]. PMID- 4161764 TI - [Vasomotor properties of mercaptoethylguanidine (MEG) in the rat]. PMID- 4161765 TI - Relationships between Bucephalus sp. and Crassostrea virginica: a histochemical study of some carbohydrates and carbohydrate complexes occurring in the host and parasite. PMID- 4161766 TI - The chemical nature and evolutionary significance of monogenean attachment sclerites. PMID- 4161767 TI - [An electrolytic method for the preparation of dihydrostreptomycin sulfate]. PMID- 4161768 TI - The syndrome associated with midsystolic click and late systolic murmur. PMID- 4161769 TI - Hyalinization of afferent and efferent glomerular arterioles in cyanotic congenital heart disease. PMID- 4161770 TI - Testosterone potentiated 32P therapy in prostatic carcinoma. PMID- 4161771 TI - Sedimentation analysis of a multiple myeloma gamma-G-globulin and one of its mercaptoethylamine reaction products. PMID- 4161772 TI - Sedimentation analysis of a papain-digested human multiple myeloma gamma-G globulin. PMID- 4161773 TI - [N-acetylneuraminic acid in the blood serum and standard clinical tests of so called acute phase in the treatment of chronic progressive rheumatism]. PMID- 4161774 TI - A comparison of currently popular thyroid function tests. PMID- 4161775 TI - A rapid polychrome stain for epoxy-embedded tissue. PMID- 4161776 TI - A simple rapid method for staining epoxy-embedded specimens for light microscopy with the polychromatic stain paragon-1301. PMID- 4161777 TI - Ceruloplasmin rise and PBI fall in serum due to diphenylhydantoin. PMID- 4161778 TI - Federal air pollution prevention and abatement responsibilities and operations. PMID- 4161779 TI - The internal membranes of Caulobacter crescentus. PMID- 4161780 TI - A histological and histochemical study of the glands of the external auditory canal of the dog. PMID- 4161781 TI - Differentiation of epithelial and connective tissue components in the tongue of Gallus domesticus. PMID- 4161782 TI - Accumulations of fat in the brains of mice affected with scrapie. PMID- 4161783 TI - Observations on the mineral composition and staining properties of the inclusion bodies of infectious canine hepatitis. PMID- 4161784 TI - Measurement of the colloid osmotic pressure in serum with Tybjaerg Hansen's osmometer. PMID- 4161785 TI - Studies on the immunoglobulin spectrum of porcine serum and colostrum. PMID- 4161786 TI - [Treatment of angina pectoris with the association of a duodenal heparinoid and )O-(beta-diethylaminoethoxy)phenyl propiophenone]. PMID- 4161787 TI - Observations on the use of progesterone impregnanted tampons in a herd of Dorset Hill sheep. PMID- 4161789 TI - Morphological changes in glial cells during nerve regeneration. PMID- 4161788 TI - [Lead in benzine and its consequences to health. Does the Soviet Union win biologically?]. PMID- 4161790 TI - [Gammaglobulin as a therapeutic and prophylactic drug]. PMID- 4161791 TI - Amino acid analyzer using 2,4,6-trinitrobenzenesulfonic acid. PMID- 4161792 TI - A procedure for the determination of total iodine in radioactive iodide preparations of high specific activity. PMID- 4161793 TI - Evaluation of the palliative effects of treatment with the 70-MEV synchrotron on advanced carcinoma of the bladder. PMID- 4161794 TI - Twelve cases of pulmonary mycosis. PMID- 4161795 TI - Hemodynamic features of extrasystoles in newborn and older infants. PMID- 4161796 TI - Electrophoretic patterns in adult sheep on a magnesium-deficient diet. PMID- 4161797 TI - Application of miniature goats in ruminant research. PMID- 4161798 TI - The biochemical effects of coumaphos and three oximes on certain enzyme systems and blood protein elements in cattle. PMID- 4161799 TI - Spontaneous atherosclerosis in the arterial system of aging swine. PMID- 4161800 TI - Identification and virulence studies of Brucella strains isolated from Eskimos and reindeer in Alaska, Canada, and Russia. PMID- 4161801 TI - Pathogenesis of skunk rabies virus: rabies inhibiting substance as related to rabies diagnosis. PMID- 4161802 TI - Serum protein electrophoresis and serum transaminase activity of dogs with canine distemper. PMID- 4161803 TI - Right colon by-pass for inoperable carcinoma of the oesophagus. PMID- 4161804 TI - Radiology in epidemiological studies and some therapeutic trials. PMID- 4161806 TI - Ultracentrifugal studies of the reactions of rheumatoid factor with native human gamma-G-globulin. PMID- 4161805 TI - Immunocytochemical localization of the immunoglobulin factors Gm(a), Gm(b) and Inv(a) in human lymphoid tissue. PMID- 4161808 TI - The role of the sixth component of complement in some types of hypersensitivity. PMID- 4161807 TI - Recombination of heavy and light chains from human immunoglobulins. PMID- 4161809 TI - Isolation and characterization of active fragments obtained by cleavage of immunoglobulin G with cyanogen bromide. PMID- 4161811 TI - Studies of thyroid economy in two patients with phenylketonuria. PMID- 4161810 TI - Effect of iodinated water supplies on thyroid function. PMID- 4161812 TI - Tolerance to bovine gamma-globulin in adult guinea pigs. PMID- 4161813 TI - Gamma-globulin and antibody formation in vitro. V. The secondary response made by splenic white and red pulp with reference to the role of secondary nodules. PMID- 4161814 TI - Phagocytosis by guinea pig splenic cells of Escherichia coli and protein-coated bentonite particles labeled with iodine-125. PMID- 4161815 TI - Erythroid aplasia following thymomectomy. Report of a case with a positive lupus erythematosus cell preparation and elevated plasma erythropoietin level. PMID- 4161816 TI - Reaction of adenine-specific antibodies with denatured deoxyribonucleic acid. PMID- 4161817 TI - Ultrastructural alterations in human liver disease. PMID- 4161818 TI - [Demonstration of placental tissue protein in gamma globulin preparations and initial raw materials]. PMID- 4161819 TI - [The clinical significance of serum butanol-extractable iodine determination in cases of latent hypothyroidism, especially with goiter]. PMID- 4161821 TI - [Serum proteins in children treated for rheumatic fever with prednisone]. PMID- 4161820 TI - Hereditary deficiency of the second component of complement (C'2) in man. PMID- 4161822 TI - [Evaluation of the susceptibility of Musca domestica L. to gamma-HCH. Studies on the stability of insecticidal bases containing gamma-HCH. I]. PMID- 4161823 TI - Reoperation in carcinoma of the colon following resection and adjuvant chemotherapy. PMID- 4161824 TI - A survey of 302 transvesical prostatectomies with primary closure technique. PMID- 4161825 TI - [Reversible suppression of thyroid function after long-term massive thyroid medication]. PMID- 4161826 TI - Preferential inhibition of RNA synthesis in Bacillus subtilis by actinomycin S. PMID- 4161827 TI - The importance of the growth-promoting alpha-globulin for cells in culture. PMID- 4161828 TI - Microscopical observations on the effects of phenanthroline chelates on Landschutz ascites tumour cells. PMID- 4161829 TI - [On the possibility of showing peroxidase-positive formations in the pharyngeal secretion of the premature infant]. PMID- 4161830 TI - [Genetically determined disturbances of immunologic mechanisms]. PMID- 4161831 TI - [Our experience with the health surveillance of subjects employed in the production of benzanthrone]. PMID- 4161832 TI - Technic for removal of whole retinas. SAM-TR-66-67. PMID- 4161833 TI - Mucous thread in inferior conjunctival fornix. Qualitative analyses of the normal mucous thread. PMID- 4161834 TI - Nasal decongestant properties of some tetrahydrothiophene-1,1-dioxide derivatives. PMID- 4161835 TI - Immunologic studies in ataxia-telangiectasia. I. Delayed hypersensitivity and serum immune globulin levels in probands and first-degree relatives. PMID- 4161836 TI - Do polymorphonuclear leukocytes play a role in passive cutaneous anaphylaxis of the guinea pig? PMID- 4161837 TI - Serum protein alterations induced by Listeria monocytogenes infections. PMID- 4161838 TI - The adjuvant action of endotoxin in thymectomized mice. PMID- 4161839 TI - Plasmodial mitoses and polyploidy in the Myxomycete Physarum polycephalum. PMID- 4161840 TI - [A comparative study of some methods of determination of the viability of the bone marrow cells]. PMID- 4161841 TI - [Transitional LE phenomenon after penicillin therapy]. PMID- 4161842 TI - [A rapid blood sugar determination using o-toluidin]. PMID- 4161843 TI - Field study of the effect of cold exposure and increased muscular activity upon metabolic rate and thyroid function in man. PMID- 4161844 TI - [On the problem of gamma globulin therapy of infectious diseases. Passive mice immunity studies with human gamma globulin]. PMID- 4161845 TI - [Significance of histamine and its inactivation in the pathogenesis of tuberculosis in young children]. PMID- 4161846 TI - [Differentiation of the sensitivity of Pediculus humanus humanus L. to organic chlorine insecticides with special regard to physiological and environmental conditions. II. Influence of physiological conditions (age, satiety) on the sensitivity of the cause on p,p'DDT and gamma-benzene hexachloride]. PMID- 4161847 TI - The shortest peroxidase stain time and the mean cellular peroxidase content of blood leukocytes. PMID- 4161848 TI - [Excellent effects of oral streptomycin in a case of idiopathic steatorrhea]. PMID- 4161849 TI - Unusual disease of pulmonary arteries with dyspnea. Structure-function relationships. PMID- 4161850 TI - Asymptomatic monoclonal IgA hypergammaglobulinemia. A three year study. PMID- 4161852 TI - Increased specificity of immunofluorescent reactions. PMID- 4161851 TI - Protein-bound iodine and abortion. PMID- 4161853 TI - Immunologic and histochemical studies of lymph nodes after local administration of heterologous antigenic material. I. Cellular localization of antigenic material from chrysoidin hepatoma, livers of healthy mice and human gamma globulin. PMID- 4161854 TI - Immunologic and histochemical studies of lymph nodes after local administration of heterologous antigenic material. II. Localization of antibodies, produced under the influence of antigenic material, obtained from chrysoidin hepatoma, livers of healthy mice and human gamma-globulin. PMID- 4161855 TI - Comparison of the early thyroidal iodide clearance with estimates obtained at later intervals. PMID- 4161857 TI - The properties of Shigella flexneri 1b strain carrying a lethal factor. PMID- 4161856 TI - [Comparative studies of the differentiation of Pappenheim-Wright stained blood smears in the diagnosis of leukosis]. PMID- 4161859 TI - Antibiotic edeine. II. Morphological observations on Bacillus brevis Vm4 strain. PMID- 4161858 TI - Antibiotic edeine. I. Isolation of induced high activity mutant of Bacillus brevis Vm4. PMID- 4161860 TI - The influence of sodium deoxycholate and dimethylsulphoxide on the permeability of cell membrane of Schizosaccharomyces. PMID- 4161861 TI - Falvin biosynthesis by Propionibacteria. PMID- 4161862 TI - Dynamics of amylolytic enzymes synthesis in Aspergillus oryzae. PMID- 4161863 TI - The effect of various humic fractions of peat on Bacillus subtilis and Escherichia coli. PMID- 4161864 TI - [The effect of sewage from the Poznan District on the bacterial flora of the Warta River]. PMID- 4161865 TI - Immunoglobulins in pediatric disorders an immunoelectrophoretic study. PMID- 4161866 TI - [Bleeding in inflamed skin areas following treatment with anticoagulants]. PMID- 4161867 TI - [Electron microscopic-autoradiographic studies on the collagen synthesis of fibroblasts in healing wounds]. PMID- 4161868 TI - Threonine dehydratase of streptomycin-dependent Escherichia coli K-12. PMID- 4161869 TI - Effect of freezing on the corneal endothelium. PMID- 4161870 TI - Validation of an indicator of mammalian retinal receptor response: density of stain as a function of stimulus magnitude. PMID- 4161871 TI - [On the significance and elimination of interfering inflammatory manifestations in the cytological vaginal smear]. PMID- 4161872 TI - Sequential UV-induced mutations in synchronized cultures of Escherichia coli K 12. PMID- 4161873 TI - Lysogeny in Rhizobium meliloti. PMID- 4161874 TI - Investigations on the antigenic composition of Salmonella gallinarum and Salmonella pullorum. PMID- 4161875 TI - Phospholipase C (phosphatidylcholine cholinephosphohydrolase) in Clostridium perfringens cultures. PMID- 4161876 TI - Influence of root extracts and root exudates on respiratory activity of Azotobacter. PMID- 4161877 TI - Optimal medium for synthesis of corrinoids by propionibacteria. PMID- 4161878 TI - Bacterial associations of the Vistula (black and white Vistula streams). PMID- 4161879 TI - The disinfection of infected store-rooms in archives, libraries and museums. PMID- 4161880 TI - Contamination of chrome-tanned leather by Desulfovibrio. PMID- 4161881 TI - Direct fluorescent labeling of microorganisms as a possible life-detection technique. AB - Microorganisms and selected proteinaceous substances were directly tagged with fluorescein isothiocyanate. This approach suggested a possible application for detection of extraterrestrial life. A stable and apparently specific linkage was formed with protein, and nonprotein substances were readily destained. Soil and atmospheric debris did not exhibit any significant affinity for the dye. PMID- 4161882 TI - Analysis of polycyclic aromatic hydrocarbons in petroleum waxes and white mineral oils with appraisal of merits of different methods of analysis. PMID- 4161884 TI - [On the clinical features and pathologic anatomy of carcinoma of the Meibomian gland]. PMID- 4161883 TI - Electron microscopy of guinea-pig epidermis stained by the osmium-iodide technique. PMID- 4161885 TI - [Immunological tolerance in rabbits injected with human serum heated to 60-62 degrees C]. PMID- 4161886 TI - [Thrombolytic treatment of leg ulcer and ecthyma]. PMID- 4161887 TI - The role of diabetogenic hyperinsulinism in the pathogenesis of prostatic hyperplasia and malignancy. PMID- 4161888 TI - Structure of isolated plant Golgi apparatus revealed by negative staining. AB - Sucrose-gradient-purified dictyosomes of plant Golgi apparatus appear, after glutaraldehyde stabilization, as stacks of highly fenestrate and tubate cisternae when negatively stained with phosphotungstic acid, shadowed with heavy metal, or OsO(4)-stained in thin section. The tubular proliferations (diameter 200 to 400 A) extend for several microns from the central region and are united at intervals into an anastomosing network. Associated with the tubules are two kinds of vesicles which are distinguishable on the basis of texture, size, shape, and staining characteristics. One vesicle type is rough-surfaced, nearly spherical, and of uniform dimensions (diameter approximately 600 A). Metal shadowing shows that these vesicles remain spherical after drying. The other vesicle type is smooth-surfaced and varies in both size and shape. Intercisternal elements are revealed, by negative staining, on the surface of internal cisternae after fragmentation of the dictyosome. The progressive differentiation of cisternae from the forming face to the maturing face is observed in thin sections of these isolated preparations. The morphological characteristics observed in negatively stained dictyosomes indicate regions of functional specialization within the dictyosome cisternae and reveal a dictyosome structure more extensive than that envisioned from sections. PMID- 4161889 TI - Assessment of two tests of thyroid function: serum protein bound iodine and radioiodine tracer test. PMID- 4161890 TI - Uric acid in human plasma. V. Isolation and identification of plasma proteins interacting with urate. PMID- 4161891 TI - Acute phase protein in serum of women using hormonal contraceptives. AB - Acute phase protein precipitating sonatic C-polysaccharide of pneumococci appears in serum of women under treatment with hormonal contraceptives in a significantly higher number of cases when compared with control groups. The summarized results of three preliminary studies show that in 80 control serums there were four positive specimens (5 percent) and in 80 serums from women using hormonal contraceptives there were 58 positive specimens (72.5 percent). PMID- 4161892 TI - Biodegradation of the gamma isomer of benzene hexachloride in submerged soils. AB - Determination of the residual gamma isomer of benzene hexachloride (gamma-BHC) by gas chromatography showed that the insecticide persisted longer in sterilized flooded soils than in nonsterilized flooded soils. A second addition of gamma-BHC to one of the nonsterilized soils. (55 days after the first application) disappepsilonared more rapidly than the first addition. These results strongly indicate biodegradation of gamma-BHC in flooded soils. PMID- 4161893 TI - Histochemistry of the neurosecretory substance. The fraction accounted for the neurosecretory substance selective staining by the chrome-alum hematoxylin and the aldehyde-fuchsin. PMID- 4161894 TI - [On the staining of elastic structures with janus green and neutral red inclusion staining]. PMID- 4161895 TI - [Histogenesis and histochemistry of the beta cells of the Langerhans islands in the pancreas of human embryos]. PMID- 4161896 TI - [Histochemical and autoradiographic studies on protein metabolism of the large oral salivary glands]. PMID- 4161897 TI - Effect of cortisone on anaphylactic shock in the guinea pig. PMID- 4161898 TI - Refsum's disease (heredopathia atactica polyneuritiformis). An inborn error of lipid metabolism with storage of 3,7,11,15 tetramethyl hexadecanoic acid. A review of the clinical findings. PMID- 4161899 TI - Refsum's disease (heredopathia atactica polyneuritiformis). An inborn error of lipid metabolism with storage of 3,7,11,15 tetramethyl hexadecanoic acid formal genetics. PMID- 4161900 TI - Differentiation of diffusing proteins according to their geometrical patterns. PMID- 4161901 TI - Effect of antigen on the structural configuration of homologous antibody following antigen-antibody combination. PMID- 4161902 TI - A serological study of primary thymic neoplasms. PMID- 4161903 TI - [Modification of the Pappenheim staining with Tween 80]. PMID- 4161904 TI - Complement components in three pathological sera: relation to clinical states. PMID- 4161905 TI - Some relations between the structure and the antibacterial activity of natural coumarins. PMID- 4161906 TI - Phagocytosis and immunity. The kinetics of phagocytosis. PMID- 4161907 TI - [Examination of 223 families concerning the formal genesis of Inv-polymorphism]. PMID- 4161908 TI - Advantage of three combined diagnostic procedures with I-131 for the evaluation of thyroid disorders. PMID- 4161909 TI - Classification of immunoglobulins in the dermo-epidermal junction in lupus erythematosus. PMID- 4161910 TI - Serological activity in myeloma type golbulins. PMID- 4161911 TI - Observation of the protective effect of live measles vaccines in the first year after vaccination. PMID- 4161912 TI - Study of contamination of the atmosphere by injurious road transport and industrial products. PMID- 4161913 TI - Armour's "Letter" for hypothyroidism. PMID- 4161914 TI - A study of the relationship between the mineralisation of dentine and its staining with haematoxylin in decalcified sections. PMID- 4161915 TI - [Indications for roentgenotherapy in palliative treatment of bronchial cancer]. PMID- 4161916 TI - Ferritin in synovial cells in patients with rheumatoid arthritis. PMID- 4161917 TI - Pathology of experimental haemarthrosis. PMID- 4161918 TI - Protein concentration of cantharides blisters in rheumatoid arthritis. PMID- 4161919 TI - Substructure in negatively stained microtubules of mammalian blood platelets. PMID- 4161921 TI - Conflict and violence. PMID- 4161920 TI - [Contribution on the demonstration of the tongue nerve fibers in the human fetus by silver impregnation staining method]. PMID- 4161922 TI - [A comparative study of methods for inducing experimental atherosclerosis in albino rats]. PMID- 4161923 TI - The innervation of the periodontal membrane as observed by the apoxestic technique. PMID- 4161924 TI - Periodontal disease in experimental animals subjected to chronic cold stress. PMID- 4161926 TI - [On the problem of differential staining of live and dead microorganisms with acridine orange using the Strugger method]. PMID- 4161925 TI - Clinical and histological evaluation of gingival massage in the treatment of chronic gingivitis. PMID- 4161927 TI - Some observations on the histochemical localisation of phosphorylase in the nervous tissues of parrot (Psittacula krameri). PMID- 4161928 TI - [On crystalline amyloid]. PMID- 4161929 TI - Some ultrastructural changes in adrenal cortical cells of rat after hypophysectomy and following ACTH administration. PMID- 4161931 TI - [Epididymitis and prostatectomy]. PMID- 4161930 TI - Specific inhibition of mast cell disruption in vitro. PMID- 4161932 TI - [Action of 1-triiodothyronine on the blood protein-bound iodine (PBI 127) in euthyroid subjects]. PMID- 4161933 TI - [Evaluation of quantitative changes in Kulchitskii's cells detected with Fast Red B in the duodenum of the frog (Rana temporaria L.)]. PMID- 4161934 TI - Immunohistochemical study of human malignant melanoma for the presence of gamma globulin. PMID- 4161935 TI - Localization in the kidney of antibodies to human skin and malignant melanoma. PMID- 4161936 TI - Concentration of gamma-A-globulin in serum, saliva, and nasopharyngeal secretions of infants and children. PMID- 4161937 TI - Use of visual memory in teaching written language skills to deaf children. PMID- 4161938 TI - A method for eliciting naming behavior from aphasic patients. PMID- 4161939 TI - The gamma globulins. IV. Therapeutic uses of gamma globulin. PMID- 4161940 TI - [Criticism on Ertels's and Dorsts's expressive phonetic symbolism]. PMID- 4161941 TI - [On the deceptive methodology in experiments on phonetic symbolism. Reply to Taylor's criticism and criticism on Taylor]. PMID- 4161942 TI - [Studies on the demonstration of cell-bound antigammaglobulins in primary chronic polyarthritis and other diseases]. PMID- 4161943 TI - [Visualization in the practical teaching of prosthodontics and maxillofacial injuries]. PMID- 4161944 TI - [Blood as a therapeutic agent]. PMID- 4161945 TI - 3-hydroxyanthranilic acid-mediated respiration in the inhibited respiratory chain. PMID- 4161946 TI - Studies of the biosynthesis of thyroxine. II. Solubilization and characterization of an iodide peroxidase from thyroid tissue. PMID- 4161948 TI - [Vital staining of mucous membranes. Specific staining with fluorescein, rose bengal and alcian blue]. PMID- 4161947 TI - Laboratory and clinical studies of 2-phenylalanine-8-lysine vasopressin (octapressin). PMID- 4161949 TI - [Morphological and physical-optic studies on Achilles and patellar tendons]. PMID- 4161950 TI - Functional morphology of the pars intermedia of the rat hypophysis as revealed with the electron microscope. II. Correlation of the pars intermedia with the hypophyseo-adrenal axis. PMID- 4161951 TI - Behavior of immunoglobulins and some natural and acquired antibodies in chronic lymphatic leukemia. PMID- 4161952 TI - Acute subvalvar mitral incompetence. PMID- 4161953 TI - [Refsum's disease: heredopatia atactica polineuritiformis]. PMID- 4161954 TI - Studies on alpha-2-macroglobulin. 3. Isolation and properties of Erinaceus alpha 2-macroglobulin. PMID- 4161955 TI - [Reaction of the neural elements of the gastrointestinal tract to the radiation effect due to total x-ray irradiation]. PMID- 4161956 TI - The ability of patients with herdopathia atactica polyneuritiformis to alpha oxidize and degrade several isoprenoid branch-chained fatty structures. PMID- 4161957 TI - [Congenital chickenpox]. PMID- 4161959 TI - Elevated PBI, free thyroxine, and plasma protein concentration in man at high altitude. PMID- 4161958 TI - [Biological activities of chlormadinone acetate. (I). Analysis of hormonal activities]. PMID- 4161960 TI - Hyperparathyroidism in acromegaly. Findings in three cases. PMID- 4161961 TI - Dietary regulation of cholesterol metabolism. PMID- 4161962 TI - Further information on the antibody response to wart virus. PMID- 4161963 TI - Central venous pressure and direct serial measurements as guides in blood-volume replacement. PMID- 4161964 TI - Six cases of gamma-D myelomatosis. PMID- 4161965 TI - How many blows make an F.E.V.1.0? PMID- 4161966 TI - Incidence of unwanted effects of dihydrocodeine bitartrate in healthy volunteers. PMID- 4161967 TI - A test for pyloric regurgitation. PMID- 4161968 TI - Measurement of A.D.P.-induced platelet aggregation and A.D.P.-splitting enzymes in plasma. PMID- 4161970 TI - Prognosis in alcoholism. PMID- 4161969 TI - Prediction of ischaemic heart-disease. PMID- 4161971 TI - Who will vaccinate the vaccinators? PMID- 4161972 TI - Postural control of urinary incontinence. The curtsy sign. PMID- 4161973 TI - Immunology of sarcoidosis. PMID- 4161974 TI - Anticoagulants during dental surgery. PMID- 4161975 TI - Isaac Harvey Flack. PMID- 4161976 TI - Jejunal biopsy: criteria and significance. PMID- 4161977 TI - Histamine in guinea pig tissues. PMID- 4161978 TI - [The functional state of the thyroid gland in patients suffering from neurosis with marked neurovegetative disturbances]. PMID- 4161979 TI - [The results of struma resection in hyperthyroidism]. PMID- 4161980 TI - [Diffuse mesothelioma of the pleura]. PMID- 4161981 TI - Polymorphism of heavy-chain genes in immunoglobulins of wild mice. AB - The serums of 123 wild mice from six different geographic locations in the United States contain five of the six known heavy-chain antigenic determinants that have been identified in immunoglobulin of inbred laboratory strains of mice. On the basis of the distribution of determinants in inbred strains,44 of the mice were judged to be heterozygotes of various combinations and two had combinations of determinants that were unusual and could only have occurred in laboratory inbred mice by recombination. PMID- 4161982 TI - The formation of immunoglobulins by human tissues in vitro. II. Quantitative studies. PMID- 4161983 TI - The formation of immunoglobulins by human tissues in vitro. 3. Spleen, lymph nodes, bone marrow and thymus. PMID- 4161984 TI - The formation of immunoglobulins by human tissues in vitro. I. The methods and their specificity. PMID- 4161986 TI - Thyroid and steroid hormones and their relation to serum lipid concentrations in man. PMID- 4161985 TI - The formation of immunoglobulins by human tissues in vitro. IV. Circulating lymphocytes in normal and pathological conditions. PMID- 4161987 TI - Endemic goiter in Greece: metabolic studies. PMID- 4161988 TI - Effect of prednisone on thyroxine-binding proteins. PMID- 4161989 TI - Action of potassium iodide on thyroxine metabolism. PMID- 4161990 TI - The effect of epsilon aminocaproic acid on the healing of extraction wounds in hamsters. PMID- 4161991 TI - Chronic oral candidiasis and leukoplakia. PMID- 4161992 TI - Effect of 5,5'-diphenylhydantoin on the metabolism of L-thyroxine-131-I in the rat. PMID- 4161993 TI - Further studies on inhibitory effect of excess iodide on thyroidal hormone release in the rat. PMID- 4161994 TI - Effects of structure and iodine content of the rat thyroid on the distribution of 127-I and 131-I between particulate and soluble thyroidal protein-bound iodine. PMID- 4161995 TI - Chloramphenicol-, dihydrostreptomycin-, and kanamycin-inactivating enzymes from multiple drug-resistant Escherichia coli carrying episome 'R'. PMID- 4161996 TI - Involvement of the adrenal cortex in the appearance of rat slow alpha-2-globulin. PMID- 4161997 TI - Vital staining of the granulated juxtaglomerular cells in the mouse kidney. PMID- 4161998 TI - Transplantation of homo- and heterogenous tendon stored in meda solution. PMID- 4161999 TI - [Antagonists of the K-vitamins]. PMID- 4162000 TI - [Antimitotic effects of substances extracted from the Paris mushroom Psalliota campestris. Influence on vegetable embryos of actinomycin]. PMID- 4162001 TI - [Estrogenic and anti-estrogenic activity of chlormadinone in rats]. PMID- 4162002 TI - [Hypersensitivity for exogenous histamine in histamine deficient rats]. PMID- 4162003 TI - The slow response of the human cortex to auditory stimuli: recovery process. PMID- 4162004 TI - The fronto-striatal arrest response in man. PMID- 4162005 TI - Rhythmic activity in the EEG of newborns. PMID- 4162006 TI - Psychophysiological study on the depth of sleep in normal human subjects. PMID- 4162007 TI - Behavior disorders of childhood. PMID- 4162008 TI - Electrophysiological and behavioural changes following selective and reversible inactivation of lower brain-stem structures in chronic cats. PMID- 4162009 TI - Thalamo-cortical activity during increased gravitational stress. PMID- 4162010 TI - Cortical sensory evoked potentials during limbic seizures. PMID- 4162011 TI - The effect of stimulation of certain skin areas on the extensor motoneurons in the phasic reaction of a stretch reflex in normal human subjects. PMID- 4162012 TI - Conative control of the contingent negative variation. PMID- 4162013 TI - Adjustable stimulating and recording electrodes in brain of the unrestrained animal. A study of red nucleus. PMID- 4162014 TI - [Nerve block with a new local anesthetic (Rec 7/0518) in tumoral painful syndromes]. PMID- 4162015 TI - Degenerative joint disease in cattle. PMID- 4162016 TI - Antigenic heterogeneity of human immunoglobulin A proteins. AB - Two types of human IgA myeloma proteins were distinguished by immunochemical tests. Seven of 51 IgA-myeloma proteins contained an an tigenic determinant that was not de tected in the other 44 proteins. The distinctive antigenic site was not dem onstrated on either the heavy or light polypeptide chains. PMID- 4162017 TI - Mast cells in rat gastrointestinal mucosa. I. Effects of fixation. PMID- 4162018 TI - Mast cells in rat gastrointestinal mucosa. 2. Dye-binding and metachromatic properties. PMID- 4162019 TI - Heterogeneity of anti-gamma-globulin factors detected by pepsin-digested human gamma G-globulin. PMID- 4162020 TI - Reaction of human anti-antibodies with incomplete anti-D and its sub-units. PMID- 4162021 TI - Picric acid staining of serum paraproteins. PMID- 4162022 TI - The Nobel Foundation. PMID- 4162023 TI - Viral carcinogenesis. PMID- 4162024 TI - The sodium pump. PMID- 4162025 TI - Psychology of color preference in projection slides (from Kircher to Koch). PMID- 4162026 TI - Macromolecular organization of hemocyanins and apohemocyanins as revealed by electron microscopy. PMID- 4162027 TI - Absence of tolbutamide effect on anticoagulant therapy. PMID- 4162028 TI - Atypical leukemia. PMID- 4162029 TI - Primary amenorrhea. A cytogenetic and endocrinologic study of 18 cases. PMID- 4162030 TI - Progesterone caproate in the treatment of endometrial cancer. PMID- 4162031 TI - [Possibilities of the use of neuroleptoanalgesic substances in therapy of pain in cancer patients]. PMID- 4162033 TI - Studies on components of RNA in cardiac muscle with emphasis on the rapidly labeled 4 to 18 S fraction. PMID- 4162034 TI - [Pemphigus vulgaris. Treatment with gamma globulin. Theoretic fundamentals]. PMID- 4162032 TI - [Activity of certain enzymes of intermediate metabolism and behavior of serum proteins and their fractions in workers exposed to strong acoustic and vibrational stimuli]. PMID- 4162035 TI - [Progressive hypergammaglobulinemic hepatitis]. PMID- 4162036 TI - The gamma globulins. I. The structure and synthesis of the immunoglobulins. PMID- 4162037 TI - The gamma globulins. I. The structure and synthesis of the immunoglobulins. PMID- 4162038 TI - Antibodies to human growth hormone. Development during therapy with human growth hormone. PMID- 4162039 TI - Efficacy of Actifed as a decongestant. PMID- 4162040 TI - [Gamma A and gamma M immunoglobulins studied with the immunodiffusion method in patients with malignant tumors; their behavior during radiotherapy]. PMID- 4162041 TI - [Clinical trial of a new drug with antispastic and analgesic action]. PMID- 4162042 TI - The gamma globulins. II. Hypergammaglobulinemia. PMID- 4162043 TI - [Intravenous anticoagulation with warfarin (Marevan) in surgery]. PMID- 4162044 TI - Influence of adrenal cortex on synthesis of alpha-2-AP globulin of rat serum. PMID- 4162045 TI - Antigen induced histamine release from platelets of rabbits producing homologous PCA antibody. PMID- 4162046 TI - Differential nucleic acid metabolism of planarial segments. PMID- 4162047 TI - Absence of serum alpha-2 globulin in Niemann-Pick disease. A measure of hepato cellular involvement. PMID- 4162048 TI - [Protein-bound iodine and blood bilirubin: trial correlation in normal term newborn infants]. PMID- 4162049 TI - Pendred's syndrome in South African Bantu brothers. PMID- 4162050 TI - Graves' disease in a 5-year-old child. PMID- 4162051 TI - Accumulation of I-131 by channel catfish (Ictalurus punctatus) ovaries in vivo and in vitro. PMID- 4162052 TI - Cytochemical studies on leucocyte alkaline phosphatase by naphthol AS-MX phosphate Fast Blue RR staining method from the pediatric aspects. I. Leucocyte alkaline phosphatase activity in healthy children. PMID- 4162053 TI - [Encephalitis following 1st smallpox vaccination despite pretreatment with vaccine antigens]. PMID- 4162054 TI - Collagen profile in various clinical conditions. PMID- 4162055 TI - Some effects of oral contraceptives on carbohydrate metabolism. PMID- 4162056 TI - Some effects of oral contraceptives on serum-lipid and lipoprotein levels. PMID- 4162057 TI - Accumulation of serum-albumin at the operative wound site as a cause of postoperative hypoalbuminaemia. PMID- 4162058 TI - Cephaloridine in the treatment of urinary proteus infections. PMID- 4162059 TI - Immunochemical glucagon in human pancreas, gut, and plasma. PMID- 4162060 TI - Effect of cyclandelate on cerebral cortex perfusion-rates in cerebrovascular disease. PMID- 4162061 TI - Gastric secretion in early childhood. PMID- 4162062 TI - Pool's cryoprecipitate and exhausted plasma in the treatment of von Willebrand's disease and factor-XI deficiency. PMID- 4162063 TI - Inhibition of insulin secretion by a phaeochromocytoma. PMID- 4162064 TI - A blow on the head. PMID- 4162065 TI - Sugar diarrhoea. PMID- 4162066 TI - Russell's viper and the cascade. PMID- 4162067 TI - Sudden death and phenothiazines. PMID- 4162068 TI - Family-planning advice after abortion. PMID- 4162069 TI - Klinefelter's syndrome and diabetes mellitus. PMID- 4162070 TI - Autoantibodies in Klinefelter's syndrome. PMID- 4162071 TI - Effect of stimulation and suppression of the thyroid gland upon production of iodoprotein in man. PMID- 4162072 TI - Use of phenazine methosulfate in enzyme histochemistry of human muscle biopsies. PMID- 4162073 TI - [Gamma globulin therapy in domestic animals]. PMID- 4162074 TI - [Prostatic hypertrophy and prostatic cysts in dogs]. PMID- 4162075 TI - Induced metachromasia as an histochemical and histological method. PMID- 4162076 TI - On the double innervation of the parotid gland. An experimental study. PMID- 4162077 TI - Cholinesterases in the walls of the great arterial trunks and coronary arteries. PMID- 4162078 TI - Serum anti-gamma-G globulin factors in paroxysmal nocturnal hemoglobinuria. PMID- 4162079 TI - [Histochemical color reactions (Wurmbach-Poland and Fasske-Stein methods) on dental tissues]. PMID- 4162080 TI - Serum protein in an aging population with particular reference to evaluation of immune globulins and antibodies. PMID- 4162081 TI - Methylene-C14-dioxyphenyl compounds: metabolism in relation to their synergistic action. AB - The methylene-C(14) group is hydroxylated yielding formate-C(14) in the microsome reduced nicotinamide-adenine dinucleotide phosphate system in vitro and yielding expired C(14)O(2), in living mice and houseflies. Methylenedioxyphenyl compounds apparently serve as alternate substrates for this enzymatic hydroxylation system of microsomes, and thus reduce the rate of metabolism and prolong the action of certain drugs and insecticide chemicals. PMID- 4162083 TI - Effect of local heat in vivo on the fine structure of the basement membrane and the sertoli cells of the rat testis. PMID- 4162082 TI - Hormone-induced alterations of ovarian morphology. PMID- 4162084 TI - Electron microscopy of paraffin-embedded material in amyloidosis. PMID- 4162085 TI - Pathological, rickettsiological and immunofluorescence studies of a case of Q fever endocarditis. PMID- 4162086 TI - Intracerebral tumours of reticular tissue: the problem of microgliomatosis and reticulo-endothelial sarcomas of the brain. PMID- 4162087 TI - Characterisation of an antiserum to human growth hormone and the localisation of the hormone in the normal adult adenohypophysis. PMID- 4162088 TI - The pituitary acidophil: a comparison of its staining reactions with anti-human growth-hormone and thioflavine T. PMID- 4162089 TI - Argentaffin granules and lung tumours. PMID- 4162090 TI - Eosinophil turnover in the rat during primary and secondary antibody response to tetanus toxoid. PMID- 4162091 TI - Radiation--facts versus fears. PMID- 4162092 TI - Postoperative psychiatric disturbance. PMID- 4162093 TI - Reversible agglutination of trypsinised red cells by a gamma-M-globulin synthesized by the human foetus. PMID- 4162094 TI - Urinary hormone metabolites in cancer and benign hyperplasia of the prostate: a multivariate statistical analysis. PMID- 4162095 TI - Antibody molecules: discontinuous heterogeneity of heavy chains. AB - The heavy polypeptide chains of antibody ( and of gammaG-immnunoglobulin) molecules show discrete bands on disc electrophoresis. The same bands are present for chains from antibodies of the same or diverse specificities. Individual bands are of different intensities for chains from the different rabbits tested even if the antibodies are directed against the same hapten. The bands appear to represent classes of heterogeneous H-chains of the same size having discrete differences in mizobilities with respect to a single charge difference. PMID- 4162096 TI - Alpha globulin injections and decreased gamma globulin production in chickens. AB - Electrophoretic analysis shows a strong similarity in the blood serums of chickens subjected to egg parabiosis and of chickens repeatedly injected with fraction IV (alpha globulins). In both instances there is an evident rise in the albumin-plus alpha(1) titer and an evident decrease in the gamma globulin levels. These findings suggest that the injection of alpha globulins has the same serum effect on the animal as parabiotically induced blood chimerism, namely, a reduction in circulating gamma globulin (immunoglobulins?). PMID- 4162097 TI - Gm(a) grouping in neonates and children. PMID- 4162098 TI - Prevention of Rh-haemolytic disease: results of the clinical trial. A combined study from centres in England and Baltimore. PMID- 4162099 TI - Spinal-fluid gamma-globulin and multiple sclerosis. PMID- 4162100 TI - Immunoglobulin levels in atopic eczema. PMID- 4162101 TI - Inhibiting effect of desensitization on release of histamine from guinea pig lung by specific antigen. PMID- 4162102 TI - Physicochemical properties of reaginic antibody. 3. Further studies on the reaginic antibody in gamma-A-globulin preparations. PMID- 4162103 TI - The characterization of human antibody to heterologous serum protein. PMID- 4162104 TI - Special aids for the 1967 National Children's Dental Health Week. Bureau of Dental Health Education. PMID- 4162105 TI - Incorporation of protein and nucleic acid precursors into frog nervous tissue in vitro. PMID- 4162106 TI - Initial dietary influences on antibody absorption in newborn puppies. PMID- 4162107 TI - Immunophoretic evaluation of blood serum proteins in chickens. I. Changing protein patterns in chickens according to age. PMID- 4162108 TI - Immunophoretic evaluation of blood serum proteins in chickens. 3. Effects of nutritional myopathy-producing diets deficient in vitamin E and sulfur amino acids. PMID- 4162109 TI - Effect of condensed phosphates on vitamin D-induced aortic calcification in rats. PMID- 4162110 TI - Serum proteins in NZB/Bl and related strains of mice. PMID- 4162111 TI - Subgroups of gamma-A immune globulins. PMID- 4162112 TI - [Pathogenetic role of the LE phenomenon]. PMID- 4162114 TI - The behavior of rabbit antigens and allotypic antibodies in experimental posttransfusion shock. PMID- 4162113 TI - [On the significance of the protective action of antihistaminics in the field of dermatology]. PMID- 4162115 TI - Audio-visual aids to learning. PMID- 4162116 TI - Globulins in dystrophia myotonica. PMID- 4162117 TI - Thiochrome: a convenient synthesis from thiamine. PMID- 4162118 TI - [Presence of a slow alpha-2-globulin during immunologic polyarthritis determined by Freund's adjuvant]. PMID- 4162119 TI - Quantitative N-terminal amino acid analysis by thin layer chromatography. PMID- 4162120 TI - [A variation of the bichromate-esmium acid-fixation for the nervous system]. PMID- 4162121 TI - Studies on the serum gamma-A-globulin level. IV. Conditions with pathological proteins (M-components) in serum. PMID- 4162122 TI - The serum gamma M-globulin level in health subjects, hypergammaglobulinemic patients and conditions with pathological proteins (M-components) in serum. PMID- 4162123 TI - [On the light cells in the rat ductus epididymis]. PMID- 4162124 TI - Detection of preclinical atherosclerosis. PMID- 4162125 TI - Immunologic structure of horse antitoxic beta-2a-globulin. PMID- 4162126 TI - The influence of specific antibody on the disappearance of staphylococcal enterotoxin B from blood. PMID- 4162127 TI - Effects of prolonged ethanol intake in man: role of dietary adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. PMID- 4162128 TI - Assay of materials used in immunofluorescence techniques. AB - Samples of commercially available fluorescein isothiocyanate and conjugated antispecies globulins were evaluated. Only one of the samples was of very high quality. There was great variation in the quality of the conjugated globulin solutions and even the best of them showed defects. PMID- 4162130 TI - Reconstitution of dried-up tissue specimens for histological examination. PMID- 4162129 TI - The occurrence of abnormal serum proteins in patients with epithelial neoplasms. AB - In a series of 99 patients with paraproteinaemia, nine had carcinoma without myeloma. A review of the literature suggests that this may be a significant association, and its theoretical and clinical significance is discussed. PMID- 4162131 TI - The biology of fungous infections of the feet. PMID- 4162132 TI - [Human immunoglobulin against tetanus--but it is expensive]. PMID- 4162133 TI - Antigenic determinants common to human immunoglobulins G and M: importance of conformational antigens. AB - Antiserums produced against certain isolated human myeloma IgGglobulins and absorbed in order to show only individual antigenic specificity crossreact with certain Waldenstrom IgM-globulins. Some of the common antigenic determinants revealed by these cross-reactions depend on the tertiary and quaternary structure of the IgG and IgM molecules and are independent of their K and L light-chain antigenic types. PMID- 4162134 TI - The orthochemistry of immune globulins. PMID- 4162135 TI - The pathochemistry of the immunoglobulinopathies. PMID- 4162137 TI - Management of the gammopathies. PMID- 4162136 TI - Clinical and pathogenic immunoglobulinopathies. PMID- 4162138 TI - Bacteria in Whipple's disease. Isolation of a Haemophilus strain from the jejunal propria. PMID- 4162139 TI - Kidney lesions in rats with severe long-term alloxan diabetes. 2. Histochemical studies, comparison with human diabetic glomerular lesions. PMID- 4162140 TI - In vitro abrogation of the inhibitory action of tumour ascitic fluid on the oncolytic reaction. PMID- 4162141 TI - A comparative study of the effects of morphine in unanaesthetized and anaesthetized cats. PMID- 4162142 TI - Small bowel obstruction secondary to hematoma of the mesentery. PMID- 4162143 TI - [A fully automatic method of determination of protein-bound iodine in the blood serum]. PMID- 4162144 TI - Isolation and amino-acid sequence of beta-LPH from sheep pituitary glands. PMID- 4162145 TI - Electrophoretic mobility of an immune globulin from rainbow trout serum. PMID- 4162146 TI - Gm(b) factor in the gamma globulin of non-human primates. PMID- 4162147 TI - Comparative investigation of immune globulins of various vertebrate classes. PMID- 4162149 TI - The staining of malaria parasites. PMID- 4162148 TI - Clinical and pathological observations with special reference to the nervous system in Macaca radiata infected with Kyasanur Forest Disease virus. PMID- 4162150 TI - Immunoelectrophoretic analysis of guinea pig sera. PMID- 4162151 TI - Mechanism of the inhibition of enzymatic halogenation by antithyroid agents. PMID- 4162152 TI - Role of the thymus in tolerance. 3. Tolerance to bovine gamma globulin after direct injection of antigen into the shielded thymus of irradiated rats. AB - Rats subjected to high doses of whole-body irradiation, with simultaneous shielding of the thymus or spleen, recovered at 3 wk the ability to develop delayed sensitization and to form hemagglutinating and precipitating antibody following foot-pad injection of BgammaG in complete adjuvant. Injection of BgammaG into the shielded thymus immediately after irradiation, in amounts between 20 gammag and 40 mg, inhibited these response to later challenge partially or completely. A comparable effect on immune responses to BgammaG was not seen after injection of heterologous antigen (Ea) intrathymically, BgammaG intraperitoneally, or BgammaG into the shielded spleen. However high doses (20 or 40 mg) of antigen given by the latter routes resulted in some diminution of later response. Arthus reactivity recovered partially in the spleen-shielded group and was readily suppressed by intrasplenic administration of antigen. PMID- 4162153 TI - Recombination of heavy and light chains of human gamma-a-myeloma proteins: formation of hybrid molecules and configurational specificity. AB - The present studies demonstrate that the conditions necessary for reductive cleavage, isolation, and recombination of L and H polypeptide chains of human gammaA-myeloma globulins parallel those required for similar manipulation of the component chains of gammaG-globulin. Specificity of recombination was shown for chains derived from the same protein. In contrast, no intradass preferential recombination was demonstrable. Hybrid molecules, formed by reassociation of noncovalent bonds, could be synthesized from isolated chains of two immunoglobulin classes resulting in the formation of molecules of the type gammaA H-gammaG-L and gammaG-H-gammaA-L. Several sera containing both gammaA- and gammaG "monoclonal" peaks were studied, one of which demonstrated the L chains associated with both peaks to be identical both by electrophoretic mobility in acid-urea gel and antigenic analysis. The possibility is considered that this case represents a naturally occurring analogue of the artificially produced hybrid molecules described in this study. Configurational antigenic specificity of gammaA-myeloma proteins, imposed by the presence of kappa L chains in native and appropriately recombined molecules, provides a further indication of the importance of noncovalent bonds in the establishment of the quaternary structure of these proteins. PMID- 4162154 TI - Genetically determined antigen of the Ne subgroup of gamma-globulin: detection by precipitin analysis. AB - A genetic antigen, Gm(n), has been described for the Ne subgroup of gamma globulin previously devoid of Gm factors. It was detected by precipitin tests with a primate antiserum to Ne-type heavy chains. A relation to the Gm(b) antigens of the Vi subgroup and the Gm(f) and Gm(y) antigens of the We subgroup was apparent. The availablity of genetic antigens for the heavy chains of three subgroups of gamma-globulin with varying relationships in different populations offers an approach to the mapping of the genes concerned. PMID- 4162155 TI - Multiple sclerosis: correlation between immunoglobulin-G in cerebrospinal fluid and brain. AB - There is a positive correlation between the concentration of immunoglobulin-G in plaques of demyelination due to multiple sclerosis (as well as in white matter of normal appearance) and the concentration of this globulin in the cerebrospinal fluid. The tentative conclusion drawn from these results was that, in patients with multiple sclerosis, the increase in immuno-globulin-G in the cerebrospinal fluid is a reflection of an excess of this globulin in the brain. PMID- 4162156 TI - Correlation of localization of alkaline and acid phosphatases with morphological development of the rat kidney. PMID- 4162157 TI - Morphological variability of keratohyalin. PMID- 4162158 TI - New aspects of immunogenetic relations between child and mother. I. Children produce antibodies against their mother's antigen. PMID- 4162159 TI - Electronmicroscopic studies of isolated yeast mitochondria with negative staining and thin sectioning methods. PMID- 4162160 TI - Extracts of plasma and serum toxic for mammalian cells cultured in vitro. PMID- 4162161 TI - Growth hormone replacement therapy. PMID- 4162162 TI - Ultrastructural studies in hypertension. I. Comparison of renal vascular and juxtaglomerular cell alterations in essential and renal hypertension in man. PMID- 4162163 TI - Ultrastructural studies in hypertension. II. Renal vascular changes in progressive systemic sclerosis. PMID- 4162164 TI - The antigastric-antibody test as a screening procedure for vitamin-B12 deficiency in psychiatric practice. PMID- 4162165 TI - Enzyme and isoenzyme studies in preinvasive carcinoma of the cervix. PMID- 4162166 TI - Quantitative estimation of bilirubin in liquor amnii. PMID- 4162167 TI - Long-term assessment of steroid therapy in childhood nephrosis. PMID- 4162168 TI - A study of retinal vascular occlusion using fluorescein angiography. PMID- 4162169 TI - Hypergammaglobulinaemia, antibody deficiency, autoimmune haemolytic anaemia, and nephritis in an infant with a familial lymphopenic immune defect. PMID- 4162170 TI - Candida albicans and the contraceptive pill. PMID- 4162171 TI - The effects of propantheline on gastric-acid secretion after vagotomy. PMID- 4162172 TI - Haemodynamic and metabolic effects of hyperbaric oxygen in myocardial infarction. PMID- 4162173 TI - Blood-gas changes after acute myocardial infarction. PMID- 4162175 TI - A simple device for external cooling. PMID- 4162174 TI - Effect of anti-lymphocyte globulin on kidney disease in (N.Z.B. x N.Z.W.) F 1 mice. PMID- 4162176 TI - How much illness do viruses cause? PMID- 4162177 TI - Madras--and after. PMID- 4162179 TI - The pink spot: a red herring? PMID- 4162178 TI - Abnormal calcification of cartilage. PMID- 4162180 TI - Errors in the classification of fatal pericarditis. PMID- 4162181 TI - Fluoridation. PMID- 4162182 TI - Chemotherapy in Burkitt's Tumour. PMID- 4162183 TI - Methyldopa and hemolytic anemia. PMID- 4162184 TI - [Plastic surgery of reversed stomach as the palliative method of treatment in cases of inoperative cancer of the cardia]. PMID- 4162185 TI - Fine structure of lily pollen tubes following various fixation and staining procedures. PMID- 4162186 TI - The role played by the natural anti-thyroidal substances of food and fodder in the apparition of endemic goitre. PMID- 4162187 TI - A strain of transplantable thyroid gland tumor of rats. PMID- 4162188 TI - Physicochemical properties and antigenic activity of fragments of human gamma globulin obtained by action of ultrasound. PMID- 4162189 TI - Cytochemical investigation of decidual cells of human placenta. PMID- 4162190 TI - Immunization with protein-cellulose co-polymer (immunosorbent). PMID- 4162191 TI - [Automobiles as source of harmful substances]. PMID- 4162192 TI - A rapid fluorochromatic tissue stain for frozen section diagnosis. PMID- 4162193 TI - [Routine prostatectomy in association with amputation of the rectum]. PMID- 4162194 TI - Effect of aortic-caval fistula on experimental atherosclerosis in dogs. PMID- 4162195 TI - How topical application of fluorides protects teeth. PMID- 4162196 TI - Unusual case of a nonagenarian with reticulum-cell sarcoma presenting as acute haemolytic anaemia. PMID- 4162197 TI - Cytochemical identification of protein amino acids in the cell coat of mouse ascites tumor cells. PMID- 4162198 TI - Animal experiments concerning the aetiology of viral hepatitis. PMID- 4162199 TI - Studies on the experimental salmonellosis. Hypersensitivity against the endotoxin and appearance of hyaline granules in mice immunized under various conditions. PMID- 4162200 TI - [Determination of insecticidal residue of chlorinated hydrocarbons (lindane and aldrin) in foodstuffs by means of Drosophila melanogaster. Preliminary report]. PMID- 4162201 TI - Preparation and properties of 3,5-di-Op-anisoyl-1,2-dideoxy-D-erythropentofuranos 1-ene. Various p-anisoylated derivatives of D-ribofuranose. PMID- 4162202 TI - The synthesis of N-benzylthieno[2,3-b]pyrrole. PMID- 4162203 TI - Viruses in the aetiology of acute appendicitis. PMID- 4162204 TI - The gamma globulins. II. Hypergammaglobulinemia. PMID- 4162205 TI - Evoked responses to clicks and tones of varying intensity in waking adults. PMID- 4162206 TI - Electroencephalographic-behavioral dissociations during animal hypnosis. PMID- 4162207 TI - Electroencephalographic studies in toads. PMID- 4162208 TI - Demonstration of averaged operant potentials in the human EEG. PMID- 4162209 TI - Unusual EEG in coma after cardiac arrest. PMID- 4162210 TI - Electroencephalographic and clinical changes in an epileptic child during repeated photic stimulation. PMID- 4162211 TI - A miniature stimulating electrode set. PMID- 4162212 TI - The application of electro-luminescence to photic stimulation. PMID- 4162213 TI - Permanently implanted recording electrodes for immature animals. PMID- 4162214 TI - [Considerations on the interpretation of thymol tests, in correlation with electrophoretic and immunoelectrophoretic data]. PMID- 4162215 TI - [Sound-image display. A contribution to the intensification of instruction]. PMID- 4162216 TI - Emissions of polynuclear hydrocarbons from automobiles and trucks. PMID- 4162217 TI - Pharmacodynamic correlations between acetylcholine and potassium. PMID- 4162218 TI - Evidence that choline can exchange for hydrogen across proximal tubules of dogs. PMID- 4162219 TI - Histaminergic transmission in a frog vagus stomach muscle preparation. PMID- 4162220 TI - [Metabolism of phosphorus esters in the Rana temporaria sartorius treated with a hypertonic Ringer solution]. PMID- 4162221 TI - [Protein nutrition in Tenebrio molitor L. VII. New attempts at replacement of casein by preparations of amino acids]. PMID- 4162222 TI - Acetylcholinesterase in Tribolium confusum Duval. PMID- 4162223 TI - The proteolytic activity in brain. PMID- 4162224 TI - Metabolism in the crayfish Astacus astacus (L.). 3. Absence of cholesterol synthesis. PMID- 4162225 TI - Changes in haemolymph proteins in first instar locusts. PMID- 4162226 TI - Effects of strontium ions on heart muscle. I. Influences on contractility. PMID- 4162227 TI - Effects of strontium ions on heart muscle. II. Influence on excitability, conduction and potassium efflux. PMID- 4162228 TI - Studies on the phosphorylase activity in isolated perfused rat heart. PMID- 4162229 TI - Vagal escape time in rabbit heart and effect of serpasil. PMID- 4162230 TI - Unit activity of thalamic and hypothalamic neurons during thalamic spreading depression in rats. PMID- 4162231 TI - [Comparison between porcine and bovine pituitary thyrotropin]. PMID- 4162232 TI - [The association of podophyllum derivatives and cyclophosphamide in the palliative therapy of female pelvic neoplasms]. PMID- 4162233 TI - Changes after splenectomy of plasma protein pattern in Banti's syndrome. PMID- 4162234 TI - Effect of thiouracil-type drugs on the alpha-glycerophosphate dehydrogenase response to thyroxine analogs. PMID- 4162235 TI - Immune globulin levels in colostrum and breast milk, and serum from formula- and breast-fed newborns. PMID- 4162236 TI - Wall charts. An aid to resuscitation. PMID- 4162237 TI - Further studies on the chemotactic factor of complement and its formation in vivo. PMID- 4162239 TI - Some aspects of the surgical treatment of intracranial aneurysms. PMID- 4162240 TI - Hemorrhagic diabetic retinopathy. Treatment by pituitary stalk section or by pituitary irradiation with protons at the Bragg peak. PMID- 4162241 TI - Contributions of stereoencephalotomy to the body-mind problem. PMID- 4162238 TI - Tolerance of turkey gamma-globulin in chickens. PMID- 4162242 TI - Experimental and clinical studies of radiosensitizers in brain tumors, with special reference to BUdR-antimetabolite continuous regional infusion-radiation therapy (BAR therapy). PMID- 4162243 TI - [Histochemical study of the nucleic acids in cerebral tumors with fluorochromatization technics]. PMID- 4162244 TI - Effect of immunosuppressive therapy on the intrarenal distribution of blood flow in dog renal allograft rejection. PMID- 4162245 TI - Intracranial localization of substances used for brain scanning. PMID- 4162246 TI - [The postnatal development of adrenal functions in the golden hamster (Mesocricetus auratus). I. Histochemical tests for the presence of medulla hormones]. PMID- 4162247 TI - [The importance of histological pretreatment in studies of the blood-brain barrier with fluorescent labelled proteins]. PMID- 4162248 TI - [Contrasting of thin sections with barium chloride. A method for the topochemical determination of substances with incompletely esterified sulfuric acid groups in the submicroscopic area]. PMID- 4162249 TI - Long-term outcome of hyperthyroidism treated with antithyroid drugs. PMID- 4162250 TI - Rapid redistribution of serum thyroxine during ether anesthesia. PMID- 4162251 TI - Norethynodrel-mestranol and thyroid function. PMID- 4162252 TI - Effect of L-tyrosine upon the protein bound iodine in thyrotoxicosis. PMID- 4162253 TI - [Comparative value of some indicators of lipid metabolism in arteriosclerosis]. PMID- 4162254 TI - [Laboratory control in anticoagulant therapy]. PMID- 4162255 TI - [On the clinical value of the study of the adhesive capacity of thrombocytes]. PMID- 4162256 TI - [The halometric method of determination of the mean diameter of erythrocytes]. PMID- 4162257 TI - [Electronic semi-automatic apparatus for measuring the diameter of erythrocytes]. PMID- 4162258 TI - [Photometric standardization of erythrocyte suspensions]. PMID- 4162259 TI - [Automatic recording of erythrograms by the EFA-1 densitometer]. PMID- 4162260 TI - [On the method of making an induced test of intravascular hemolysis]. PMID- 4162262 TI - [A simplified method of gastric juice electrophoresis]. PMID- 4162261 TI - [A method of determination of the residual oxidizability of the cerebrospinal fluid and its clinical value]. PMID- 4162263 TI - [Clinical value of the Waaler-Rose reaction and carbonic agglomeration (carbo test) in rheumatoid arthritis]. PMID- 4162264 TI - [A test for detection of C-reactive protein in psychiatric diseases]. PMID- 4162265 TI - [On the standardization of the RNGA method in listeriosis]. PMID- 4162266 TI - [On the problem of the specificity of the passive hemagglutination reaction and antibody neutralization in plague]. PMID- 4162267 TI - [On the value of the heterohemagglutination reaction in Botkin's disease]. PMID- 4162268 TI - [A comparative study of nutrient media for the determination of antibiotic sensitivity in diphtheria bacteria]. PMID- 4162269 TI - [A comparative study of nutrient media for isolation of diphtheria bacteria]. PMID- 4162270 TI - [Quantitative determination of riboflavin in the urine by the fluorometric method]. PMID- 4162272 TI - [Fluorometric determination of griseofulvin]. PMID- 4162271 TI - [A fluorometer for the determination of catecholamines in living tissues]. PMID- 4162273 TI - [Augmentation of the sensitivity of the EF-3M fluorometer by a semi-conducting triode attachment]. PMID- 4162274 TI - [A semiautomatic attachment to the polarograph for work with a revolving hard electrode]. PMID- 4162275 TI - [A simple appliance for unidimensional paper chromatography]. PMID- 4162276 TI - [A simple cuvette for descending chromatography]. PMID- 4162277 TI - [An improved calorimeter]. PMID- 4162278 TI - [On the use of a BK-4 type viscosimeter for the standardization of the viscosity of hyaluronic acid]. PMID- 4162279 TI - Mechanism of a histochemical reaction differentiating between adrenaline- and noradrenaline-storing cells in the electron microscope. PMID- 4162280 TI - Elevated cord macroglobulins in the diagnosis of intrauterine infections. PMID- 4162281 TI - [Effect of blocking of thyroid hormone synthesis on the iron absorption in the rat intestine]. PMID- 4162282 TI - Two-stage surgical treatment of complete transposition of the great vessels. PMID- 4162283 TI - Fibrillation in empty and loaded ventricles. An experimental study of coronary artery ligation during partial and complete cardiac bypass. PMID- 4162284 TI - Production of 7 S immunoglobulins in immunized guinea pigs. PMID- 4162285 TI - Presence of identical antigenic determinants in the Fd fragments of gamma-1- and gamma-2-guinea pig immunoglobulins. PMID- 4162286 TI - Ontogeny of the immune response. II. Characterization of 19S-gamma-G- and 7S gamma-G-immunoglobulins in the true primary and secondary responses in piglets. PMID- 4162287 TI - Studies on the mechanisms of hypersensitivity phenomena. XIV. Passive sensitization in vitro of human leukocytes to ragweed pollen antigen. PMID- 4162288 TI - The immune response to azo-human gamma-globulin conjugates in mice tolerant to human gamma-globulin. PMID- 4162289 TI - The immunologic significance of antigen induced lymphocyte transformation in vitro. PMID- 4162290 TI - A possible role of gamma-A-immunoglobulin in herpes simplex virus infection in man. PMID- 4162291 TI - Fatal brain damage after dental anaesthesia. Its nature, etiology, and prevention. PMID- 4162292 TI - Fibrinolytic activity in pregnancy, during parturition, and in the puerperium. PMID- 4162293 TI - Postmortem findings in 25 cases of sudden heart arrest in the perioperative period. PMID- 4162294 TI - Relation between long-acting thyroid stimulator and thyroid function in thyrotoxicosis. PMID- 4162295 TI - Effect of oestriol on platelet adhesiveness and fibrinolysis in men. PMID- 4162296 TI - Effect of alteration of species source of insulin on insulin-antibody levels. PMID- 4162297 TI - Myocardial infarction associated with severe factor-XII deficiency. PMID- 4162298 TI - 125-I-labelled fibrinogen in cerebral malaria. PMID- 4162299 TI - Test for ovarian function and responsiveness leading to ovulation induction. PMID- 4162300 TI - A diffraction method for measuring the average sizes and shapes of red blood cells. PMID- 4162301 TI - Spontaneous "transformation" of lymphocytes from the umbilical-cord vein. PMID- 4162302 TI - Acclimatisation to cold. PMID- 4162303 TI - Spontaneous regression of cancer. PMID- 4162304 TI - An insulin hazard? PMID- 4162305 TI - Schistosomiasis. PMID- 4162306 TI - Surgery under adverse conditions. PMID- 4162307 TI - Drug surveillance utilizing nurse monitors. An epidemiological approach. PMID- 4162308 TI - [Chronic intermittent extracorporeal hemodialysis and kidney transplantation as a therapeutic measure in chronic renal insufficiency. 2]. PMID- 4162309 TI - [Silver impregnation of the connective tissues. Considerations on the properties of the precollagen reticular tissue and proposed technical procedure]. PMID- 4162310 TI - The production of a state of active immunity to isologous and autologous serum proteins. PMID- 4162311 TI - A method for separation and quantitation of LDH isoenzymes on cellulose acetate. PMID- 4162312 TI - Role of gastroenterostomy in management of pancreatic carcinoma. Risk of duodenal obstruction after biliary bypass. PMID- 4162313 TI - [Action of histamine-liberating drugs on histamine levels and on cardiac anaphylaxis]. PMID- 4162314 TI - [Interference of noradrenaline and pronethalol on histamine liberation from peritoneal cells of the rat in vitro]. PMID- 4162315 TI - Studies on the serum proteins of chimeras. I. Identification and study of the site of origin of donor type serum proteins in adult rat-into-mouse chimeras. PMID- 4162316 TI - Studies on the serum proteins of chimeras. II. Rat gamma globulin formation in neonatal mice with graft-versus-host reaction induced by rat spleen or thymus. PMID- 4162317 TI - Kapok allergens. PMID- 4162318 TI - Carcinoma of the prostate: an analysis of 136 cases treated at the Veterans Administration Hospital, Tuskegee, Alabama, 1950-1960. PMID- 4162319 TI - Combined positive inotropic interaction of quindonium and ouabain. PMID- 4162320 TI - Fibrinolytic treatment of rheumatoid arthritis with phenformin plus ethyloestrenol. PMID- 4162321 TI - Impotence in patients with temporal-lobe lesions. PMID- 4162322 TI - A transferable factor causing abnormal platelet behaviour in vascular disease. PMID- 4162323 TI - Acetylsalicylic acid as a cause of pancytopenia from bone-marrow damage. PMID- 4162324 TI - Possible chemical factors in the postnatal development of rubella cataracts. PMID- 4162325 TI - Effects of age on the loss of bone after gastric surgery. PMID- 4162326 TI - Impaired delayed hypersensitivity in patients with lepromatous leprosy. PMID- 4162327 TI - Nasal carriage of Staphylococcus aureus in diabetes mellitus. PMID- 4162328 TI - Dependence of serum-uric-acid on haemoglobin and other factors in the general population. PMID- 4162329 TI - Growth hormone and kwashiorkor. Role of protein in growth-hormone homoeostasis. PMID- 4162330 TI - Porphyrin-binding effect of cholestyramine. Results of in-vitro and in-vivo studies. PMID- 4162331 TI - Disposable arterial and venous sets with connectors for use with the modified two layer Kiil kidney. PMID- 4162332 TI - Tuberculosis and immigration. PMID- 4162333 TI - Coeliac disease. PMID- 4162334 TI - Aspirin and the blood. PMID- 4162335 TI - Chemotherapy of Burkitt's lymphoma. PMID- 4162336 TI - Changes in the incidence of neural-tube defects. PMID- 4162337 TI - Blunt abdominal trauma in head injuries. PMID- 4162338 TI - Some effects of oral contraceptives on serum lipid and lipoprotein levels. PMID- 4162339 TI - Mitogenic action of papain. PMID- 4162340 TI - Fatal poisoning with methaqualone and diphenhydramine. PMID- 4162341 TI - [Research for the demonstration of nucleolar RNA in vegetables]. PMID- 4162342 TI - [Studies on glycoproteins. Nature of the glycan-protein attachment point in gamma G globulins of human blood]. PMID- 4162343 TI - Use of technetium-99m in studying thyroid physiology in the mouse: double label experiment with technetium-99m and iodine-125. PMID- 4162344 TI - Testosterone metabolism in prostate; formation of androstan-17-beta-ol-3-one and androst-4-ene-3, 17-dione, and inhibitory effect of natural and synthetic estrogens. PMID- 4162345 TI - Constituents of Iva species. IV. Structure of pseudoivalin, a new guaianolide. PMID- 4162346 TI - The reaction of some 1-trihaloacetyl-8-methylazulenes with base. PMID- 4162347 TI - Histological evidence against the view that the cat's optic nerve contains centrifugal fibres. AB - 1. Degeneration that can be shown by the Nauta-Gygax technique in the orbital part of the cat's optic nerve does not begin until 10 days after intracranial transection of the nerve, though after enucleation of the eye it is conspicuous in 4 days.2. We were not able to tell, by any silver-staining technique applied to an optic nerve at any interval after an operation, whether at that operation the nerve had been cut peripherally only or both peripherally and centrally.3. From these and subsidiary observations we conclude that either the cat's optic nerve contains no centrifugal fibres detectable by silver staining and light microscopy, or, if there are such fibres, they are much less susceptible to prograde (Wallerian) degeneration and much more susceptible to retrograde degeneration than most of the centripetal fibres. The former is the simpler and, we suggest, the more likely conclusion. PMID- 4162348 TI - Fifty years after Flexner. PMID- 4162349 TI - Observations on mountain sickness in the Colombian Andes. PMID- 4162350 TI - Hyperacute rejection of kidney allografts, associated with pre-existing humoral antibodies against donor cells. PMID- 4162351 TI - Juvenile cirrhosis and allergic capillaritis of the skin. A hepato-cutaneous syndrome. PMID- 4162352 TI - Cytogenetic investigation of survivors of the atomic bombings of Hiroshima and Nagasaki. PMID- 4162353 TI - Hepatitis complicating chronic haemodialysis. PMID- 4162354 TI - Experimental use of cetrimide in the prevention of wound implantation with cancer cells. PMID- 4162355 TI - The use of soluble swabs in exfoliative cytology of the bronchus and hollow viscera. PMID- 4162356 TI - Hypermetabolic states. PMID- 4162357 TI - A miniature phlebogram device. PMID- 4162358 TI - A device for simplifying the measurement of central venous pressure. PMID- 4162359 TI - Catheter for bladder drainage. PMID- 4162360 TI - Pathogenesis of myotonia. PMID- 4162361 TI - Direct-current shock for atrial fibrillation. PMID- 4162362 TI - Led by the nose? PMID- 4162363 TI - Genetics of schizophrenia. PMID- 4162364 TI - Mumps embryopathy. PMID- 4162365 TI - A controlled trial of propranolol in acute myocardial infarction. PMID- 4162367 TI - The incidence of urinary infection in 5000 pregnant women. PMID- 4162366 TI - Absence of prophylactic effect of propranolol in myocardial infarction. PMID- 4162368 TI - An outbreak of urinary Pseudomonas aeruginosa infection acquired during urological operations. PMID- 4162369 TI - Muscle dysfunction in hyperthyroidism. PMID- 4162370 TI - Corticosteroid withdrawal in rheumatoid arthritis. PMID- 4162371 TI - Prolonged coma after head injury. PMID- 4162372 TI - Congenital deformities and insulin antagonism. PMID- 4162373 TI - A new technique for examining the leptomeningeal circulation. PMID- 4162374 TI - Effect of corticotrophin on growth-hormone secretion in response to insulin induced hypoglycemia in children. PMID- 4162375 TI - Failure of oral propranolol to maintain relief from paroxysmal syncopal attacks in Fallot's tetralogy after its successful intravenous use. PMID- 4162376 TI - Inhibition of experimental leukaemia by a combination of various factors. PMID- 4162378 TI - Propranolol and myocardial infarction. PMID- 4162377 TI - A social-work service for Scotland. PMID- 4162379 TI - The biology of tissue transplantation. PMID- 4162380 TI - Fibrinolysis and pulmonary embolism. PMID- 4162381 TI - Intensive therapy. PMID- 4162382 TI - Garden fertilisers as a source of salmonellae. PMID- 4162383 TI - The Minister on administration of the N.H.S. PMID- 4162385 TI - Contaminated areas in operating-theatres. PMID- 4162386 TI - Oral contraceptives and carbohydrate metabolism. PMID- 4162384 TI - Derbyshire Neck. Thyroid abnormalities in the Derbyshire Peak district. PMID- 4162387 TI - The effect of dicumarol, diphacinone and pivalyl upon blood prothrombin time of chicks. PMID- 4162388 TI - [The "Snyder test" and the "fern leaf test" as indications of the incidence of dental caries]. PMID- 4162389 TI - [Quantitative determination of protein-bound iodine with a titrimetric method]. PMID- 4162390 TI - Visual aids: their use and abuse. PMID- 4162392 TI - [Practical nursing]. PMID- 4162391 TI - The menace of the exhaust. PMID- 4162394 TI - [Chronic cor pulmonale: its clinical forms and treatment]. PMID- 4162393 TI - [Primary hyperparathyroidism]. PMID- 4162395 TI - [Collagen diseases]. PMID- 4162396 TI - [The management of ascites]. PMID- 4162398 TI - [The psychological needs of the hospitalized child]. PMID- 4162397 TI - [Salpingitis]. PMID- 4162399 TI - [The importance of observation in young nurses; problems and difficulties encountered]. PMID- 4162400 TI - [Blood transfusion incidents]. PMID- 4162401 TI - [LSD and hallucinogenic drugs]. PMID- 4162402 TI - [The National Public Health Laboratory]. PMID- 4162403 TI - [Vision problems in road security]. PMID- 4162404 TI - [Educational films]. PMID- 4162405 TI - [Nursing care of a patient with a prostatectomy for prostatic hypertrophy]. PMID- 4162407 TI - [General observations on the operative sequela in thoracic surgery. 1]. PMID- 4162406 TI - [The use of audio-visual aids in the instruction of medicine]. PMID- 4162408 TI - [Acute pericarditis]. PMID- 4162409 TI - [Multiple sclerosis]. PMID- 4162410 TI - [Acute and chronic diarrhea in adults. 1]. PMID- 4162411 TI - [The nurse versus social and economic conditions of her profession]. PMID- 4162412 TI - [The functions and education of voluntary social workers]. PMID- 4162413 TI - [2 scientific groups study 2 contraceptive methods]. PMID- 4162414 TI - [The 3d WHO report on the health status of the world]. PMID- 4162415 TI - [The prevention of cardiovascular disorders in France]. PMID- 4162416 TI - [Deontology]. PMID- 4162417 TI - [Emergency medical assistance]. PMID- 4162418 TI - [Extra-uterine pregnancy]. PMID- 4162419 TI - [Purulent pleurisy]. PMID- 4162421 TI - [Staffing of nursing personnel in a general medical service]. PMID- 4162420 TI - [Glaucoma]. PMID- 4162422 TI - [The 36th national antituberculosis stamp campaign; November 15 - December 15, 1966]. PMID- 4162424 TI - [Training Schools for Male and Female Nurses]. PMID- 4162423 TI - [The organization of the Department of Social Affairs]. PMID- 4162425 TI - Electrocardiographic findings during bronchoscopy. The apnoeic oxygenation technique. PMID- 4162426 TI - Alterations in the nocturnal sleep cycle resulting from LSD. PMID- 4162427 TI - Analysis of the frequency/voltage ratio of the EEG in intracranial diseases. PMID- 4162429 TI - Rhythmic bursts in the medullary reticular formation and their connection with agonal respiration during hypoxia and the post-hypoxic period. PMID- 4162428 TI - Stimulus-response relationship in the production of after-discharges and their spread from intact cerebral gyri to neuronally isolated slabs. PMID- 4162430 TI - A light-weight micro-pipette puller by vacuum. PMID- 4162431 TI - A cytochemical study of cytoplasmic basic proteins in echinoderm oogenesis. PMID- 4162432 TI - Quantitative cytophotometric studies of nuclear protein in Vicia faba following acute irradiation. PMID- 4162433 TI - The depression of the immune response by serum protein fractions. PMID- 4162434 TI - Gamma 1-antibodies in guinea-pigs infected with the cattle lungworm. PMID- 4162435 TI - Passive haemagglutination for estimation of early and late anti-human gamma globulin antibodies. PMID- 4162436 TI - The role of mycobacteria and silica in the immunological response of the guinea pig. PMID- 4162437 TI - Immunologic unresponsiveness in the adult guinea pig. 3. Variation of the antigen and vehicle of suppression. Induction of unresponsiveness in the adult rat. PMID- 4162438 TI - Gamma-A-immunoglobulin from rabbit colostrum. PMID- 4162439 TI - Ontogeny of the immune response. I. Development of immunoglobulins in germfree and conventional colostrum-deprived piglets. PMID- 4162440 TI - Physico-chemical properties of human reaginic antibody. IV. Presence of a unique immunoglobulin as a carrier of reaginic activity. PMID- 4162441 TI - Suppression of experimentally induced polyarthritis in the rat by heterologous anti-lymphocyte serum. PMID- 4162443 TI - Notation for genetic factors of human immunoglobulins. PMID- 4162442 TI - Risk of changing from ox to pig insulin. PMID- 4162444 TI - Factors influencing the staining of histones in irradiated rat thymocytes. PMID- 4162445 TI - The management of adequate anticoagulant therapy and its complications. PMID- 4162446 TI - [The association of ephedrine with a local anesthetic (mepivacaine) in epidural anesthesia]. PMID- 4162447 TI - The effects of antigens and of phytohemagglutinin on rabbit spleen cell suspensions. AB - Phytohemagglutinin (PHA) stimulated the rate of DNA synthesis in rabbit spleen cell suspensions. Unlike antigens, previous immunization to PHA was not necessary and the specific response could not be transferred by macrophages, although lymphocytes primed by incubation in PHA were able to stimulate other spleen cells not directly exposed to PHA. When rabbits were stimulated by in vivo immunization with antigens, spleen cells proliferating in response to antigen were stimulated to divide by in vitro contact with PHA. Using the technique of specific hemolytic plaque formation by individual cells synthesizing gammaM-antibody to sheep red cells (plaque-forming cells), no evidence was obtained that stimulation of cell division by PHA resulted in specific antibody formation, although the presence of antigen resulted both in stimulation of cell proliferation and the production of plaque-forming cells. The presence of both sheep red cells and PHA in the medium of the same cell suspensions did not enhance the production of plaque-forming cells although there was a summative effect on DNA synthesis. PMID- 4162448 TI - Structural studies of human gamma-G-myeloma proteins of different antigenic subgroups and genetic specificities. AB - 1. Peptide maps of Fc fragments or heavy chains of 36 G myeloma proteins and two "heavy chain disease" proteins belonging to the four gamma-chain subgroups revealed very striking similarities between them. However differences in a few peptides were noted. This was most pronounced for the Ge(gamma(2)d) subgroup which lacked three peptides characteristic of the other three subgroups. While Fc fragments from different proteins belonging to the same subgroup appeared very similar, minor differences in addition to those based on currently recognized Gm factors were occasionally noted. 2. Fc fragments from Gm(a+) We(gamma(2)b) proteins had a peptide previously shown to be characteristic of normal Gm(a+) gammaG-globulins. Fc fragments from Gm(a-) molecules belonging to the We(gamma(2)b), Vi(gamma(2)c), or Ne(gamma(2)a) subgroups, whether Gm(b+), Gm(f+), or Gm(-), had the peptide previously identified in Gm(b+f+) normal gammaG globulin. This "non-a" peptide was absent in peptide maps from Gm(-) molecules of the Ge(gamma(2)d) subgroup which contained instead another peptide with the same electrophoretic mobility but migrating slightly further on chromatography. 3. Both the "a" and "non-a" peptides were pentapeptides having three amino acids in common, and differing in the other two. The "a" peptide contained one residue of lysine, aspartic acid, threonine, leucine, and glutamic acid. The "non-a" peptides prepared from Gm(b+), Gm(f+), and Gm(-) proteins were identical and contained one residue of lysine, threonine, and methionine sulfone, and two residues of glutamic acid. 4. Several possible mechanisms for the origin of these differences, and their possible role in serologic specificity are discussed. PMID- 4162450 TI - The minister among the young doctors. PMID- 4162449 TI - Polymorphonuclear leukocytes in immunologic reactions. The destruction of vascular basement membrane in vivo and in vitro. AB - Vascular basement membrane was disrupted in the presence of polymorphonuclear leukocytes (PMN's) during two immunologic reactions: The Arthus phenomenon and the reaction to locally injected antibody to vascular basement membrane. This disruption was evidenced by (a) the inability of the basement membrane to retain circulating carbon, by (b) loss of antigenic constituents, and by (c) electron microscopic observation showing actual gaps in the structure of the vascular basement membrane. The factors within PMN's responsible for damage to isolated glomerular basement membrane in vitro were found by isolation procedures to be cathepsins D and E. Cationic proteins of PMN's were separable from the cathepsins. While inducing vascular permeability upon injection, these basic proteins failed to inflict the severe damage to the basement membrane observed in Arthus and antibasement membrane reactions. It is concluded that the full expression of these immunologic lesions requires destruction of the basement membrane possibly brought about by cathepsins D and E. Some of the physicochemical properties of these pathologically active leukocytic factors are given. PMID- 4162451 TI - Hydrocortisone and/or desiccated thyroid in physiologic dosage. XIX. Muscular dystrophy: creatine phosphokinase during thyroid and alpha-tocopheryl acetate therapy. PMID- 4162452 TI - Pneumocystis carinii pneumonia and altered host resistance: treatment of one patient with pentamidine isethionate. PMID- 4162453 TI - Cancer of the alimentary tract. A positive approach to palliation. PMID- 4162454 TI - Frequent or severe respiratory infections in children. PMID- 4162455 TI - Left lobe hepato-cholangio-jejunostomy in palliative treatment of malignant biliary obstruction. PMID- 4162456 TI - Initiation of irreversible differentiation in vaginal epithelium. PMID- 4162457 TI - Mammillary complex of cat brain--aspects of quantitative organization. PMID- 4162458 TI - Presence of a "cell coat" rich in carbohydrate at the surface of cells in the rat. PMID- 4162460 TI - Glomerular ultrastructure in the kidney of a hibernating animal. PMID- 4162459 TI - Cells with filopodia cultured from human synovialis. PMID- 4162461 TI - Intracytoplasmic membranes in Escherichia coli. PMID- 4162463 TI - Sound and visual teaching aids in obstetrics and gynaecology. PMID- 4162464 TI - Speaking at meetings. PMID- 4162462 TI - Freezing and in vitro culture of hamster teeth before transplantation and replantation. PMID- 4162465 TI - The epidiascope and television in medical teaching. PMID- 4162466 TI - Immunologic aberrations in the Di Guglielmo syndrome. PMID- 4162467 TI - Staining of blood cells with periodic acid/salicyloyl hydrazide (PA-SH). A fluorescent method for demonstrating glycogen. PMID- 4162468 TI - Intussusception of the ileum in a horse. A case report. PMID- 4162469 TI - Epididymitis of rams. Antibody in newborn lambs. PMID- 4162470 TI - Measles--canine distemper relationship. The effect of measles viruses and their influence on subsequent challenge with Snyder Hill distemper virus. PMID- 4162471 TI - [Studies on the prophylaxis of transfusion hepatitis with gamma globulin]. PMID- 4162472 TI - Somatic projection to the orbital cortex of the cat. PMID- 4162473 TI - Relationships of neuronal spike populations and EEG activity in chronic cats. PMID- 4162474 TI - Rubrally evoked unitary potentials in ventro-lateral thalamus of cat. PMID- 4162475 TI - Striatal connections and influences on somatosensory and photic projections to the hypothalamus. PMID- 4162476 TI - Hippocampal electrical correlates of self-stimulation in the rat. PMID- 4162477 TI - The effects of central stimulation and nasal air flow on induced activity of olfactory structures. PMID- 4162478 TI - The periodic events of subacute sclerosing leucoencephalitis. PMID- 4162479 TI - Auto- and cross-correlation of the EEG following unilateral caloric stimulation of the labyrinth. PMID- 4162480 TI - Effect of beta-phenylisopropylhydrazine (JB 516) on the isolated cerebral cortex. PMID- 4162481 TI - Insulating micro-electrodes by centrifuging. PMID- 4162482 TI - A simple noise generator for use in neurophysiological and behavioral research. PMID- 4162483 TI - [Problems of industrial hygiene and state of health of workers in the production of commercial hexachlorane]. PMID- 4162484 TI - Enhancement of antibody synthesis by 6-mercaptopurine. AB - The administration of 6-MP to rabbits led to either suppression or enhancement of antibody production, depending on when the drug was given in relation to the antigenic challenge. Maximum enhancement of antibody synthesis was found when a small dose of BGG was administered 5 days after the last dose of a 1 wk course of 6-MP. There were no indications that the macrophage system or immunological memory was affected in animals with augmented antibody synthesis. It was proposed that enhancement of antibody production by 6-MP was due to nucleic acids released from cells killed or injured by the drug. It was suggested that lymphocytes incorporating these nucleic acids were transformed into specialized cells capable of direct and immediate stimulation by antigen and lacking immunological memory (hemocytoblasts). A relatively small dose of antigen was apparently capable of stimulating all the hemocytoblasts representing a given clone) with the result that large amounts of antibody rapidly appeared in the serum. PMID- 4162485 TI - Mechanisms of immunologic injury of rat peritoneal mast cells. I. The effect of phosphonate inhibitors on the homocytotropic antibody-mediated histamine release and the first component of rat complement. AB - The ability of a number of p-nitrophenylethyl, alkyl phenylalkyl, chloroalkyl, and aminoalkyl phosphonates to inhibit the homocytotropic antibody-mediated release of histamine from rat peritoneal mast cells has been tested. The effectiveness of these same phosphonates against the activated first component of rat complement (C'1a) has also been investigated. The rat mast cell esterase activated by the reaction of antigen and homocytotropic antibody resembles chymotrypsin in its reactivity with the phenylalkyl and chloroalkyl phosphonate, but is unlike this protease in its greater responsiveness to the 5-aminopentyl phosphonate relative to the pentyl phosphonate. The antigen-homocytotropic antibody-activated mast cell esterase and chymotrypsin, thus, appear to be similar, but different enzymes; i.e., they are parazymes (see reference 4, p. 501). There are distinct differences in the pattern of inhibition given by the phenylalkyl and aminoalkyl and alkyl phosphonates of the homocytotropic antibody mediated histamine release from rat peritoneal mast cells and from guinea pig lung slices. On the basis of these differences it is concluded that the esterases activated by the combination of antigen and homocytotropic antibody on the mast cells of the two species are not the same. The arithmetic dose response curve found for the action of the phosphonates on the antigen-induced histamine release from rat peritoneal mast cells contrasted sharply with the logarithmic relationship found when these same inhibitors acted on the guinea pig lung system. This suggests that in addition to the antigen-antibody-activated esterases being unlike, the detailed mode of histamine release from the mast cells of the guinea pig lung differs from that of the mast cells of the rat peritoneum. Distinct and large differences were found in the pattern of inhibition of histamine release from rat peritoneal mast cells and of rat C'1a given by the phenylalkyl, and chloroalkyl and alkyl phosphonates implying that esterase activated by the combination of antigen with the sensitized rat peritoneal mast cells is not C'1a. Thus, the results with the peritoneal mast cells lead to the same conclusion as the previous work with guinea pig lung slices; i.e., the antigen-antibody-activated esterase involved in the homocytotropic antibody-mediated release of histamine is not part of the complement system. PMID- 4162486 TI - Mechanisms of immunologic injury of rat peritoneal mast cells. II. Complement requirement and phosphonate ester inhibition of release of histamine by rabbit anti-rat gamma globulin. AB - There is an absolute requirement for C'1, C'2, C'4, C'3, and C'5 in releasing histamine from rat peritoneal mast cells sensitized with rabbit anti-rat gamma globulin. This conclusion is based upon the restoration of histamine-releasing capacity by adding highly purified complement components to sera deficient in one or more of these components. Of special advantage was the availability of sera from humans with inborn or acquired deficiencies in a single component. The p nitrophenyl ethyl phosphonates block this reaction by inhibiting an antigen antibody-activated esterase which exists in a phosphonate resistant precursor state until activated by the interaction of the sensitized mast cell and serum complement. There is almost complete disparity between the ability of the phosphonates to inhibit complement-dependent histamine release by rabbit anti-RGG and to inactivate C'1a. Even though C'1a is required for complement-dependent histamine release by rabbit anti-RGG, this is not the esterase being blocked by the phosphonates under the experimental conditions used. The pattern of inhibition by the phosphonates of the antigen-antibody-activated esterase required for complement-dependent, noncytotoxic histamine release is remarkably similar to that of the esterase required for homocytotropic antibody-mediated histamine release. One possible implication is that these two quite different modes of carrying out antigen-antibody-induced histamine release from rat peritoneal mast cells lead to activation of the same esterase and share a common pathway. PMID- 4162488 TI - The stability of gamma-G-globulin and gamma-G related fragments in normal human urine. PMID- 4162487 TI - Quantitative studies of the immunoglobulin sequence in the response of the rabbit to a somatic antigen. AB - Employing a sensitive and immunoglobulin-specific assay method based upon antiglobulin augmentation, quantitative and qualitative aspects of the primary and secondary response of the rabbit to Salmonella typhimurium O antigens have been evaluated. These studies examine the validity of the method of assay for detecting and measuring gammaG- and gammaM-antibodies produced in response to whole organisms or its lipopolysaccharide. The results show that during the primary response gammaG-antibodies, not detectable by usual techniques, are produced in a pattern similar to that reported in animals stimulated by other classes of antigens. Moreover, the gammaG response following reinjection is characteristic of a secondary-type response. In contrast, gammaM-antibody levels after both primary and secondary stimulation rose equally to levels between 1 and 4 mg/ml. Despite increased sensitivity of detection and quantitative estimates of the actual molar concentration of each immunoglobulin, the minimal interval between gammaM and gammaG appearance in serum was not less than 1.5 days. The variable degree of augmentation of agglutination by antiglobulin reagent found during the immune response severely limits the quantitative usefulness of the methods developed. However, the data suggest that qualitative changes in anti-O antibodies interpretable as changes in avidity occur regularly during the immune response. PMID- 4162489 TI - Sensitization of mice with human IgA. PMID- 4162490 TI - Electrophoretic behaviour of H and L chains of human serum and colostrum gamma globulin. PMID- 4162491 TI - [The autoregulatory effect of iodide in hyperthyroidism]. PMID- 4162492 TI - Clinical observations on the use of propranolol in disorders of cardiac rhythm. PMID- 4162493 TI - Long term treatment of paroxysmal cardiac arrhythmias with propranolol. PMID- 4162494 TI - Immediate effects of intravenous propranolol on various cardiac arrhythmias. PMID- 4162495 TI - Determination of nonfibrin protein in fibrin clots by use of I-131-labeled protein fractions. PMID- 4162496 TI - Alterations in thyroid physiology during pneumococcal septicemia in the rat. PMID- 4162498 TI - Stoichiometric relationships in mitochondrial accumulation of calcium and phosphate supported by hydrolysis of adenosine triphosphate. PMID- 4162497 TI - Studies on deiodination occurring during pancreatin digestion of thyroid homogenates and its prevention by methimazole. PMID- 4162499 TI - A tool for clinical supervision. PMID- 4162500 TI - Sulfonamide reactions in systemic lupus erythematosus. PMID- 4162501 TI - Urine as a medium for bacterial growth. PMID- 4162502 TI - Thyroidal suppression by triiodothyronine as a guide to duration of treatment of thyrotoxicosis with antithyroid drugs. PMID- 4162503 TI - Treatment of acute retrobulbar neuritis with corticotrophin. PMID- 4162504 TI - Activity and hepatitis. PMID- 4162505 TI - 5-hydroxyindole compounds in the cerebrospinal fluid of patients with psychiatric or neurological diseases. PMID- 4162506 TI - Acute mitral incompetence after acute myocardial infarction, with successful early treatment by mitral-valve prosthesis. PMID- 4162507 TI - Acid-base status in acute myocardial infarction. PMID- 4162508 TI - Experimental "kuru" in chimpanzees. A pathological report. PMID- 4162509 TI - Change partners. PMID- 4162510 TI - Measurement of gastric acidity. PMID- 4162511 TI - Death of an asbestos worker. PMID- 4162512 TI - Saul Eli Keidan. PMID- 4162513 TI - [The renal transplant: experimental research andfirst clinical experiences]. PMID- 4162514 TI - [PBI determination. preliminary test to avoid iodine contamination by drug contaminated serum]. PMID- 4162515 TI - Cellular changes accompanying the swarming of Proteus mirabilis. II. Observations of stained organisms. PMID- 4162516 TI - Evaluation of acridine orange fluorescence test in viability studies on Escherichia coli. PMID- 4162517 TI - A new procedure for the detection and enumeration of coagulase-positive staphylococci from frozen seafoods. PMID- 4162518 TI - Sequential mestranol-chlormadinone acetate as an oral contraceptive. PMID- 4162519 TI - Propranolol (Inderal) in cardiac arrhythmias. PMID- 4162520 TI - Anticoagulant prophylaxis of thromboembolism in postsurgical patients. PMID- 4162521 TI - Serial serum immunoelectrophoretic changes and activity of tuberculosis. PMID- 4162522 TI - [Comparative paper electrophoresis studies of serum from camelidae and cattle]. PMID- 4162523 TI - A fluorescent method for staining mast cells. PMID- 4162524 TI - The application of immune electron microscopy to the demonstration of polyoma virus antigen in cultured mouse embryo cells. PMID- 4162525 TI - The transmission of immunity from mother to young and the catabolism of immunoglobulins. PMID- 4162526 TI - Effect of daily muscular exercise in patients with intermittent claudication. PMID- 4162527 TI - Oxygen uptake during and after positive-pressure ventilation for the resuscitation of asphyxiated newborn infants. PMID- 4162528 TI - Action of d-aldosterone on the electrolyte composition of human cells grown in vitro. PMID- 4162529 TI - Acetone in alveolar air, and the control of diabetes. PMID- 4162530 TI - The effect of oral sodium phosphate on the formation of renal calculi and on idiopathic hypercalcuria. PMID- 4162531 TI - Transduction of antibiotic resistance in Staphylococcus aureus. PMID- 4162532 TI - Amenorrhea after treatment with oral contraceptives. PMID- 4162533 TI - Lipolytic activity of human pituitary fractions on isolated human adipose-tissue cells. PMID- 4162534 TI - The luxury-perfusion syndrome and its possible relation to acute metabolic acidosis localised within the brain. PMID- 4162535 TI - The differentiation between oesophageal and cardiac pain. PMID- 4162536 TI - Fluid deficit and drug effect. PMID- 4162537 TI - William Arthur Edward Karunaratne. PMID- 4162538 TI - Analgesic abuse and renal disease in North-East Scotland. PMID- 4162539 TI - Portacaval transposition in the treatment of glycogen-storage disease. PMID- 4162540 TI - Effect of propranolol in mild hypertension. PMID- 4162541 TI - Oesophageal acid-perfusion in the diagnosis of precordial pain. PMID- 4162542 TI - Immunological maturation in an infant of an agammaglobulinaemic mother. PMID- 4162543 TI - Pulmonary embolectomy. A review of five cases with three survivals. PMID- 4162544 TI - Coronary thrombosis and myocardial infarction. PMID- 4162545 TI - Production of myopia in rabbits by raised body-temperature and increased intraocular pressure. PMID- 4162546 TI - Measurement of regional cerebral blood-flow during carotid ligation. PMID- 4162547 TI - The influence of red blood-cells on platelet adhesiveness. PMID- 4162548 TI - Thymitis and myasthenia gravis. PMID- 4162549 TI - Admissions and mortality in a children's ward in an urban tropical hospital. PMID- 4162550 TI - Usefulness of intermittent positive-pressure respiration in the treatment of tetanus. PMID- 4162551 TI - The laboratory diagnosis of chronic brucellosis. PMID- 4162552 TI - A dangerous rodenticide. PMID- 4162553 TI - Where hospital staff eat. PMID- 4162554 TI - Psychiatric Reports: whether and how. PMID- 4162555 TI - Philip Henry Manson-Bahr. PMID- 4162556 TI - Infusion through inferior gluteal artery for pelvic cancer. A preliminary report. PMID- 4162557 TI - The specific precipitation of reagins with an anti-beta-2A globulin serum. PMID- 4162558 TI - Patch test methods. 3. Influence of adhesive tape on test response. PMID- 4162559 TI - Histamine release from the skin of patients with cutaneous mast cell disease (urticaria pigmentosa). PMID- 4162560 TI - Griseofulvin and tuberculin sensitivity. PMID- 4162561 TI - Studies of the mechanism of ultra-violet erythema formation. 3. A method for biological testing of ultra-violet radiation sources and substances affecting the degree of erythema. PMID- 4162562 TI - Studies of the mechanism of ultra-violet erythema formation. IV. The histamine content of the skin during the process of ultra-violet and thermal erythema. PMID- 4162563 TI - Enzymic differentiation of melanin phagocytosis and synthesis. A combined dopa acid phosphatase reaction. PMID- 4162564 TI - Blood-tissue exchange in psoriatic skin. PMID- 4162565 TI - Bone marrow studies in lupus erythematosus. PMID- 4162566 TI - Extensive micropapular sarcoidosis with joint manifestations in a child. PMID- 4162567 TI - Biochemical studies in epidermolysis bullosa. PMID- 4162568 TI - The connective tissue in mice and rabbits in experimental carcinogenesis. PMID- 4162569 TI - Penicillinase-producing staphylococci in the male urethra and their effect on penicillin treatment of gonorrhoea. PMID- 4162570 TI - Immunoglobulins in the skin of patients with lupus erythematosus. PMID- 4162571 TI - Multiplication of measles virus in the presence of actinomycin D, aurantin or 5 bromodeoxyuridine. PMID- 4162572 TI - The periodic acid-Schiff reaction in neutrophil leukocytes in untreated and myleran-treated chronic myelocytic leukemia. A quantitative microspectrophotometric study. PMID- 4162573 TI - [Experimental and clinical studies on 1st transabdominal flooding of the maternal circulation with fetal erythrocytes (new aspects of Rh sensitization)]. PMID- 4162574 TI - Unusual familial goiter associated with intrathyroidal calcification. PMID- 4162575 TI - Observations concerning the binding of thyroid hormones in sera of normal subjects of varying ages. PMID- 4162576 TI - The serumtyrosine level as an index of thyroid function. PMID- 4162577 TI - Homoreactant: a naturally occurring autoantibody in rabbits. AB - Homoreactant, a factor found in the serum of every normal rabbit tested thus far, reacts specifically with buried antigenic determinants on the Fab-fragment of papain-digested autologous and homologous gammaG-globulin. It appears that rabbits normally produce naturally occurring autoantibodies. PMID- 4162579 TI - [On the use of film reproductions for the diagnosis of neuroses]. PMID- 4162578 TI - [Experiences with a gestagen-estrogen preparation (AK 103=Aconcen)]. PMID- 4162580 TI - [The dentition as a symbolic means of expression in Buddhist iconography]. PMID- 4162581 TI - Atrioventricular junctional premature and escape beats with altered QRS and fusion. PMID- 4162582 TI - [Health education material on maternal and neonatal health protection]. PMID- 4162583 TI - [Changes in blood proteins in full-term and premature newborn infants as a result of exchange transfusion]. PMID- 4162584 TI - [Evaluation of the Cliffton-Mahajan method in palliative therapy of pulmonary cancer]. PMID- 4162585 TI - [Synthesis of actinomycin-(thr-val-pro-sar-meval), the antipode of actinomycin C1]. PMID- 4162586 TI - Modification of the Brown and Brenn gram stain for the differential staining of gram-positive and gram-negative bacteria in tissue sections. PMID- 4162588 TI - New aspects of immunogenetic relations between child and mother. II. An easy way to find maternal isoagglutinins alpha and beta on their babies' cells (a modified direct coombs tehnique). PMID- 4162587 TI - Experimental amyloidosis. Structural relationships of amyloid and reticulin in tissue sections and isolated preparations. PMID- 4162589 TI - Programmed group instruction. PMID- 4162591 TI - Ultrastructure of human thyroid. A study of normal thyroid, untreated and treated diffuse toxic goiter. PMID- 4162590 TI - Studies on myoinositol. 3. On the growth promoting and lipotropic action of some fatty acid esters of myoinositol. PMID- 4162592 TI - [Cylindromatoid alteration of the hair follicles of the anal region. Report of 2 cases]. PMID- 4162593 TI - [Quantitative analyses of immune globulins (IgA, IgG, IgM) during cytostatic treatment]. PMID- 4162594 TI - Delayed ultrastructural changes in duodenal crypts of x-irradiated mice. PMID- 4162595 TI - Automotive emissions after hot and cold starts in summer and winter. PMID- 4162596 TI - Production of tolerance in immunized mice and the effects of immunosuppression. PMID- 4162597 TI - Hypogammaglobulinemia, primary and secondary: immunoglobulin levels (gamma-G, gamma-A, gamma-M) in one hundred and twenty-five patients. PMID- 4162598 TI - Studies of the control of thyroid function in endemic goiter in Eastern New Guinea. PMID- 4162599 TI - Goitrous cretinism with chromosomal aberration and defect in thyroglobulin synthesis. PMID- 4162600 TI - A new method for PAS stain of osmium-fixed araldite-embedded thick tissue sections. PMID- 4162601 TI - Double-blind study of nasal decongestion with oxymetazoline and phenylephrine in asthmatic children with rhinitis. PMID- 4162602 TI - Effect of passive immunization on the dental caries incidence of caries susceptible rats. PMID- 4162603 TI - Selective vulnerability of the blood-brain barrier in chemically induced lesions. PMID- 4162604 TI - Horse anti-pneumococcal immunoglobulins. II. Specific mouse protective activity. PMID- 4162605 TI - Uptake of dihydrostreptomycin by intact splenic cells cultured from immunized rabbits and its binding to the 40S ribosomal subunit. PMID- 4162606 TI - Experimental specific serum therapy of Staphylococcus. PMID- 4162607 TI - Monoclonal gamma-globulins in ferrets with lymphoproliferative lesions. PMID- 4162608 TI - A comparative study of amniotic fluid, maternal sera and cord sera by disc electrophoresis. PMID- 4162609 TI - Effect of 1-methyl-2-mercaptomidazole (methimazole-tapazole) on the DNA content of the rat thyroid gland. PMID- 4162610 TI - Changes in alpha-macroglobulin during malaria in the duckling. PMID- 4162611 TI - Termination of acquired immunological tolerance in mice with antigen aagregates. PMID- 4162612 TI - Thyroidectomy. PMID- 4162613 TI - The value of protein-bound iodine and triiodothyronine resin uptake in assessing thyroid function. PMID- 4162614 TI - Studies of the effects of salicylate in hyperthyroidism. PMID- 4162615 TI - [An injecting-diaphanizing-embedding technique for studying the vascular pattern of fetal human teeth]. PMID- 4162616 TI - Organochlorine pesticides in gallstones. PMID- 4162617 TI - Studies on experimental insulin immunity. I. Dynamics of insulin immunity in the guinea pig. PMID- 4162618 TI - The passive transfer of delayed hypersensitivity in the guinea-pig. I. The synergic effect of immune cells and immune serum on the 24-hour skin reaction and a study of the histology. PMID- 4162619 TI - The synthesis of radioactive fluorescein isothiocyanate. PMID- 4162620 TI - Histamine release from leukocytes of hypersensitive individuals. I. Use of several antigens. PMID- 4162621 TI - The senescent sequences of normal processes. PMID- 4162622 TI - Permeability of incipient carious enamel lesions. PMID- 4162623 TI - Cutaneous leishmaniasis encountered in Philadelphia. PMID- 4162624 TI - [Our experiences in the surgical treatment of rectal carcinoma]. PMID- 4162625 TI - [Palliative operation in rectal carcinoma]. PMID- 4162626 TI - [Paraproteinemias]. PMID- 4162627 TI - [Monoclonal gammopathy of the gamma-A type. Physiopathological notes and clinical contribution]. PMID- 4162628 TI - Electroencephalographic recordings from actively sensitized animals after various routes of challenge. PMID- 4162629 TI - The epidemic of polymorph toxic erythema in the Netherlands in 1960. The so called margarine disease. PMID- 4162630 TI - On the allergic origin of the Jarisch-Herxheimer reaction. PMID- 4162631 TI - Allergy to chromium, nickel and cobalt. PMID- 4162632 TI - The frequency of allergic diseases among relatives to patients with allergic eczematous contact dermatitis. A preliminary report. PMID- 4162633 TI - Routine patch testing. II. Proposed basic series of test substances for Scandinavian countries and general remarks on testing technique. PMID- 4162634 TI - Besnier's prurigo (atopic dermatitis) in children. PMID- 4162635 TI - Bone marrow studies in chronic leg ulcers. PMID- 4162636 TI - Absence of deep leg veins in a case of Klippel-Trenaunay-Weber syndrome. PMID- 4162637 TI - Acquired angioma. PMID- 4162639 TI - Investigation of patients suffering from generalized pruritus, with special references to systemic diseases. PMID- 4162638 TI - Thorium X in the treatment of nevus flammeus. PMID- 4162640 TI - Electron microscope observations of Kaposi's sarcoma. PMID- 4162641 TI - Agranulocytosis due to acetosulfone (promacetin). PMID- 4162642 TI - Toxic epidermal necrolysis and Stevens-Johnson's disease. PMID- 4162643 TI - Reticulohistiocytosis (lipoid dermato-arthritis) of the skin and joints. PMID- 4162644 TI - Immunoelectrophoretic analysis in acrodermatitis chronica atrophicans. PMID- 4162645 TI - Cutaneous self-mutilation and potential self-destruction in a schizoid psychopath. PMID- 4162646 TI - The inhibitory effect of dithranol (anthralin) on DNA synthesis. PMID- 4162647 TI - Cellular changes in the psoriatic epidermis. IV. Studies on the submicroscopic organization of epidermal cells of long-term tissue cultures. PMID- 4162648 TI - Glucose-6-phosphate dehydrogenase in erythrocytes of psoriatics. PMID- 4162649 TI - Discoid lupus erythematosus. A study of sex and age at onset. PMID- 4162650 TI - Urticaria changing to vitiligo provoked by electromyographic examination. PMID- 4162651 TI - Gonorrhoea in 1964. Cases treated at the Department of Dermatology, Karoliska Sjukhuset. PMID- 4162652 TI - The essence of gonorrhoea control. 3. The delineation of the male: female source ratio. PMID- 4162653 TI - The gonococcal dermatitis syndrome. Demonstration of gonococci in skin lesions by immunofluorescence. PMID- 4162654 TI - Genes and phenotypes in the Samaritan isolate. PMID- 4162655 TI - Definitive treatment of 536 cases of hyperthyroidism with I-131 or surgery. PMID- 4162656 TI - [On the possibility of simultaneous staining for polysaccharides (Schick test) and desoxyribonucleic acid (DNA) according to Felgen-Rozenbeck]. PMID- 4162657 TI - From internal combustion to electricity. PMID- 4162658 TI - Effects of dextran infusion on the adhesiveness of human blood-platelets. PMID- 4162659 TI - Cytomegalovirus mononucleosis with jaundice as presenting sign. PMID- 4162660 TI - Anal carriage as the probable source of a streptococcal epidemic. PMID- 4162661 TI - Survival of the foetus in a patient in acute renal failure. PMID- 4162662 TI - Humoral basis of carcinoid flush. PMID- 4162663 TI - Encephalitis of lethargica type in a mental hospital. PMID- 4162664 TI - 75th anniversary of the Lister Institute. PMID- 4162665 TI - Urinary infection in the two sexes. Problems of aetiology. PMID- 4162666 TI - Comparative trial of surgery and radiotherapy for the primary treatment of small celled or oat-celled carcinoma of the bronchus. First report to the Medical Research Council by the working-party on the evaluation of different methods of therapy in carcinoma of the bronchus. PMID- 4162667 TI - 5-hydroxyindoles and kinins in the carcinoid and dumping syndromes. PMID- 4162668 TI - Treatment of obesity by total fasting for up to 249 days. PMID- 4162669 TI - Effect of penicillamine on human collagen and its possible application to treatment of scleroderma. PMID- 4162670 TI - Nutrition and metabolic bone disease in old age. PMID- 4162671 TI - The behavior of the basement membrane of skin and oral lesions in patients with lichen planus, erythema multiforme, lupus erythematosus, pemphigus vulgaris, benign mucous membrane pemphigoid, and epidermolysis bullosa. PMID- 4162672 TI - Polypeptide chains of immunoglobulins from the smooth dogfish (Mustelus canis). AB - The 17S and 7S immunoglobulins of the smooth dogfish, Mustelus canis, have been characterized with respect to molecular weights, chain structure, amino acid composition, and carbohydrate content. The 17S protein had a molecular weight of 982,000; that of the 7S protein was 198,000. Both proteins had similar amino acid compositions and a carbohydrate content of approximately 8 percent. Light and heavy chains from both immunoglobulins had molecular weights of 20,000 and 72,000 respectively. Apparently both immunoglobulins belong to the same class; this class resembles the gammaM-immunoglobulins of higher vertebrates. PMID- 4162673 TI - A comparison of two different staining methods for evaluating corneal endothelial viability. PMID- 4162674 TI - The effect of antibody to L-phenylalanine mustard conjugate on malignant cells selectively marked through "early inflammatory-like" vascular permeability. PMID- 4162675 TI - Studies on the mechanism of template stability. I. The effect of actinomycin on the base composition and sedimentation of 32P-labeled RNA in rat liver. PMID- 4162676 TI - Learning and memory in the immune response. PMID- 4162677 TI - The influence of infection upon serum protein changes in severe burns. PMID- 4162678 TI - Brucellosis among veterinary surgeons. PMID- 4162679 TI - [Agar gel electrophoresis of cerebrospinal fluid proteins. Semiology of the gamma zone]. PMID- 4162680 TI - [The gamma globulins of the cerebrospinal fluid in multiple sclerosis]. PMID- 4162681 TI - Relation of variations in activation order to intraventricular pressures during premature beats. PMID- 4162682 TI - Hypertensive angiopathy in familial chloride diarrhea. PMID- 4162683 TI - Rapid staining of juxtaglomerular cell granules and renal tubular mitochondria for light microscopy. PMID- 4162684 TI - The sympathetic chain in patients with diabetic and alcoholic polyneuropathy. PMID- 4162685 TI - Effects of x-irradiation on the antigenic character of Agkistrodon piscivorus (cottonmouth moccasin) venom. PMID- 4162686 TI - Narcotic blockade. PMID- 4162687 TI - Solitary mast cell "tumor" of lung. Its place in the spectrum of mast cell disease. PMID- 4162688 TI - Automating cancer cytodiagnosis by determining unbound acridine dye. PMID- 4162689 TI - Metabolism of gammexane in flies, ticks and locusts. PMID- 4162690 TI - [Attempts at using Hale's reaction to detect acid mucopolysaccharides with the electron microscope]. PMID- 4162691 TI - [The value of determining PBI in the diagnosis of functional states of the thyroid gland]. PMID- 4162692 TI - [Experimental studies on post-transfusion active and passive shocks due to incompatibility of the group serum proteins (gamma globulins)]. PMID- 4162693 TI - The indirect fluorescent anti-body technic and the diagnosis of the connective tissue diseases. PMID- 4162694 TI - Serum protein changes in Capillaria obsignata infections. PMID- 4162695 TI - Apparatus and technique for cryosurgery of the prostate. PMID- 4162696 TI - The clinical significance of increased activity of urinary lactic dehydrogenase. PMID- 4162697 TI - [Toluidine blue staining of thin Epon sections]. PMID- 4162698 TI - Animal exposure chambers in air pollution studies. PMID- 4162699 TI - [Regeneration of myelinic fibers and osmio-iodurophilic reaction]. PMID- 4162700 TI - [Characterization and isolation of A immunoglobins from the gastric mucosa]. PMID- 4162701 TI - [Prophylaxis of virus infections]. PMID- 4162702 TI - Neocortical influence on the amygdala. PMID- 4162703 TI - [Spinal and bulbar localization of the afferent somesthetic pathways to the ventro-lateral thalamus of cat]. PMID- 4162704 TI - Organization of somatic sensory mechanisms in the macaque cerebral cortex. PMID- 4162705 TI - Cerebral somatosensory responses evoked during sleep in the cat. PMID- 4162706 TI - Temperature changes in the rabbit brain during paradoxical sleep. PMID- 4162707 TI - Electroencephalography in old age: dominant alpha pattern. PMID- 4162708 TI - Headache and the EEG. PMID- 4162709 TI - Prevention of air embolism in the decerebrate preparation. PMID- 4162710 TI - A computer technique for evaluation of recovery cycle of the H reflex in the abnormal movement disorders. PMID- 4162711 TI - Surgical immobilization of the eye and pupil, permitting stable photic stimulation of freely moving cats. PMID- 4162712 TI - Studies on the transfer of human delayed-type hypersensitivity. I. Partial purification and characterization of two active components. PMID- 4162713 TI - [On the determination of inorganic phosphate in biological fluids]. PMID- 4162714 TI - Effects of detergents on guinea pig skin. Histological studies after single exposure to anionic, cationic and non-ionic surfactants. PMID- 4162715 TI - Studies of the mechanism of ultra-violet erythema formation. II. The effect of an increased and a reduced serotonin content of experimental animals. PMID- 4162716 TI - Cellular localization and quantitation of tritiated antigen in mouse lymph nodes during early primary immune response. PMID- 4162717 TI - Radiation necrosis and repair in rat fetal cerebral hemisphere. PMID- 4162718 TI - Lactate dehydrogenase in urinary tract disease. PMID- 4162719 TI - Inhibition of antibody production by ribonucleases. PMID- 4162720 TI - The use of immunoadsorbents for the fractionation of rheumatoid factor and rabbit anti-human gamma-G antibodies. PMID- 4162721 TI - Electrophoretic pattern of heat induced antibody-protein complexes. PMID- 4162722 TI - New metabolites of imipramine. PMID- 4162724 TI - [Staining properties of Tiazol Yellow in connective pulp tissue]. PMID- 4162723 TI - [Staining method for the morphological study of the rat dental follicle]. PMID- 4162725 TI - Physician , heal thyself... PMID- 4162726 TI - Re-evaluation of the effect of estrogen on thyroid activity in the rat and its mechanism. PMID- 4162727 TI - Evidence for heterogeneous turnover of iodine in rat thyroid glands. PMID- 4162728 TI - Effect of a malignant tumor on thyroxine metabolism and thyroid function in the rat. PMID- 4162729 TI - High and low energy states of cytochromes. I. In mitochondria. PMID- 4162730 TI - High and low energy states of cytochromes. II. In submitochondrial particles. PMID- 4162731 TI - High and low energy states of cytochromes. 3. In reactions with cations. PMID- 4162732 TI - [Studies on the efficacy of prophylactic gamma globulin in infectious hepatitis in institutions for children]. PMID- 4162733 TI - Quantitative variations in L chain types in guinea pig antihapten antibodies. AB - In guinea pig purified antihapten antibodies, the proportion of molecules bearing the kappa- or lambda-type of L chains (K or L molecules) may diverge markedly from that found in normal gamma(2)-globulins. This has been evaluated by precipitation of I(131)-labeled antibody preparations using a specific anti lambda-chain antiserum. Anti-DNP antibodies isolated 3 wk after immunization of guinea pigs with DNP(65)-BGG antibodies, contain less than 1% of L molecules, while in pipsyl antibodies, isolated from the sera of animals immunized with pipsyl-BGG, the proportion of L molecules is significantly greater than in normal gamma(2)-globulins. Anti-DNP antibodies produced against conjugates of this hapten with carriers other than BGG (BSA, OVA, or poly-L-lysine) or with BGG with a small number of DNP groups (DNP(10)-BGG) contained a greater proportion of lambda-chain bearing molecules than anti-DNP antibodies isolated from late sera of guinea pigs immunized with highly conjugated DNP(65)-BGG. An increased percentage of L molecules was detected in preparations of anti-DNP(65)-BGG antibodies isolated early (10 days), when compared to those isolated later during the course of immunization. However, the level of L molecules in all these anti DNP antibody preparations was always considerably below that present in normal gamma(2)-globulin. The relative amounts of L molecules in distinct immunoglobulin families (gamma(1) and gamma(2)) in antibody preparations isolated from individual animals was remarkably similar. PMID- 4162734 TI - Phylogenetic origins of antibody structure. II. Immunoglobulins in the primary immune response of the bullfrog, Rana catesbiana. AB - The anuran amphibian, Rana catesbiana, has been found to possess at least two kinds of immunoglobulins corresponding to gammaG- and gammaM-classes. These classes have the same chain structures as those of their counterparts in higher animal species. Light chains of both immunoglobulins had molecular weights of 20,000. Heavy chains of the gammaM-class had molecular weights of 72,100; those of the gammaG-class had molecular weights of 53,600. The carbohydrate content of the gammaG-immunoglobulin was 2.1%, and that of the gammaM-protein was 10.8%. The amino acid compositions of the immunoglobulins were generally similar to those of mammalian immunoglobulins. After a single injection of phage antigen (f2), the order of appearance of phage-neutralizing activity in the frog immunoglobulin classes was (a) gammaM-antibodies, and (b) gammaG-antibodies. The results of this and previous studies suggest that the gammaG-immunoglobulins emerged at some point in evolution between the elasmobranchs and the anuran amphibians. PMID- 4162735 TI - Studies on Echinostomatidae (Trematoda) in Malaya. 13. Integumentary papillae on six species of Echinostome cercariae. PMID- 4162736 TI - Studies on Echinostomatidae (Trematoda) in Malaya. XIV. Body gland cells in cercariae of Echinostoma audyi Lie and Umathevy, and E. lindoense Sandground and Bonne. PMID- 4162737 TI - [Experience in the treatment of mycosis fungoides with aurantin]. PMID- 4162738 TI - Serum alpha-fetoprotein, albumin, and gamma-G-globulin in the human conceptus. PMID- 4162739 TI - Dilution dependent autoinhibition of agglutination in rheumatoid arthritis sera and rabbit anti-human gamma-G antisera. PMID- 4162740 TI - Immunoglobulin production in human leukemia cell lines. PMID- 4162741 TI - Immunoglobulin classes of neutralizing antibody formed after human inoculation with soluble adenoviral antigens. PMID- 4162743 TI - C'-1 fixation by human isoagglutinins: fixation of C'-1 by gamma-G and gamma-M but not by gamma-A antibody. PMID- 4162742 TI - Inhibition of spleen cell DNA synthesis by autologous macrophages. PMID- 4162744 TI - Gamma-M and gamma-G antibodies in mice: dissociation of the normal immunoglobulin sequence. PMID- 4162745 TI - Refsum's disease: a disorder of lipid metabolism. PMID- 4162746 TI - Hypertensive disease and cerebral oedema. PMID- 4162747 TI - [Recent myocardial infarction in the immunoelectrophoretic picture]. PMID- 4162748 TI - A safe and effective method of administering 5-fluorouracil to adrenalectomized patients. PMID- 4162749 TI - Detection of venous thrombosis in the human by means of radioiodinated antifibrin fibrinogen antibody. PMID- 4162750 TI - A study of the effects of intra-arterial immunosuppressive drug therapy on canine renal allografts. PMID- 4162751 TI - True hermaphrodism in a rhesus monkey. PMID- 4162752 TI - Histology and radioautography of induced benign enlargement of the mouse prostate. PMID- 4162753 TI - Familial emphysema and alpha-1-antitrypsin deficiency. PMID- 4162754 TI - [Even a Dental Information Agency needs educational material]. PMID- 4162755 TI - Reactions of rheumatoid factor with natural human antibodies. PMID- 4162756 TI - Increase of L-chain proteins in the sera of patients with systemic lupus erythematosus and the synovial fluids of patients with peripheral rheumatoid arthritis. PMID- 4162757 TI - Mechanisms of renal injury in systemic lupus erythematosus. PMID- 4162758 TI - An in vitro system for studying hormonal induction of hepatic gluconeogenic enzymes. PMID- 4162759 TI - Ultrastructure of basidiospores and mycelium of Lenzites saepiaria. AB - Hyde, James M. (University of Mississippi Medical School, Jackson), and Charles H. Walkinshaw. Ultrastructure of basidiospores and mycelium of Lenzites saepiaria. J. Bacteriol. 92:1218-1227. 1966.-Ungerminated and germinated basidiospores and 2-day-old mycelial cultures of Lenzites saepiaria were similar in their fine structure. Fixation with glutaraldehyde, followed by osmium tetroxide, was far superior to permanganate. Cell organelles were seen in cytoplasm of spores and hyphae, and clamp connections were abundant in hyphal elements. Numerous lomasomes, vesicular bodies, and complex concentric membranes occurred in the cytoplasm and were often associated with the cell membrane or the dolipore membrane (parenthesome) of the septum. Endoplasmic reticulum was not found, but numerous ribosomes were seen; polyribosome groupings were frequently noted. The nucleus was bounded by a double membrane which contained few pores. Germinating spores exhibited one or more large osmiophilic bodies in association with a vacuole and membranous elements. Other than possessing a thin wall, the emerging germ tube was similar in structure to the parent spore. PMID- 4162760 TI - Immunofluorescent antibody studies of a murine leukemia virus. AB - Brown, Eric R. (Northwestern University Medical School, Chicago, Ill.), Peter Buinauskas, and Steven O. Schwartz. Immunofluorescent antibody studies of a murine leukemia virus. J. Bacteriol. 92:978-982. 1966.-Correlation was close between in vitro complement fixation, immunodiffusion, and passive cutaneous anaphylaxis tests with the S-63 and GC murine leukemia viruses and immunofluorescence reactions with these viruses. When fluorescein-isothiocyanate conjugated convalescent sera obtained from mice initially infected with S-63 leukemia virus were used, the reactive site was within the cytoplasm of the infected cell. By electron microscopic examination, virus particles were demonstrated in the same areas within the cells that exhibited specific fluorescence with the conjugates. Spleen and mesenteric nodes contained the most virus, whereas kidney tissues contained the least amount. Fluorescence was not observed within the nuclei of infected cells. PMID- 4162761 TI - [Serum gamma globulin levels in members' families of patients with systemic lupus erythematosus]. PMID- 4162762 TI - Wheezing associated with respiratory tract infections in children. The role of specific infectious agents in allergic respiratory manifestations. PMID- 4162763 TI - Antithyroid and antiadrenocortical activity of aminoglutethimide. PMID- 4162764 TI - A simple method for estimating serum thyroxine concentration in thyroid disease and iodine-treated patients. PMID- 4162765 TI - [On the problem of goitrogenic properties of some vegetables grown in Uzbekistan]. PMID- 4162766 TI - [On the construction of an elastic pressure bandage from soft plastic material in extensive perforations of the faciocervical region]. PMID- 4162767 TI - Correlation of structural and functional recovery from cirrhosis in rats treated with lipotropic diets. PMID- 4162768 TI - [Research on tricyclic psychotropic drugs. Dibenzothiadizepines]. PMID- 4162769 TI - A comparison of two principles for evaluating corneal endothelial viability. PMID- 4162770 TI - [The effect of actinomycin on protein synthesis in large rat liver cytoplasmic granules and microsomes]. PMID- 4162771 TI - Observations on the epidemiology of prostatic hyperplasia in Wales. PMID- 4162772 TI - Anaplastic carcinoma of the thyroid with abnormal circulating iodoprotein: a case simulating subacute thyroiditis. PMID- 4162773 TI - [Electrocorticogram and unitary activites with expanding lesions in man]. PMID- 4162774 TI - A simple electronic method for graphing EEG sleep patterns. PMID- 4162775 TI - A technique for precision multi-channel evoked response averaging. PMID- 4162776 TI - The use of 131-I-labelled albumin and amberlite IRA-400 in determination of protein-losing enteropathy. PMID- 4162777 TI - Evolution of immunoglobulin polypeptide chains: carboxy-terminal of an IgM heavy chain. AB - The dipeptide sequence at the carboxy-terminal of a heavy (micro) chain from a human macroglobulin ( IgM) is tyrosylcysteine, although the reverse sequence, cysteinyltyrosine, has not been rigorously excluded. The presence of cysteine at the carboxy-terminal was predicted from a recognition of the chemical homologies among the polypeptide chains of immunoglobulins, and their probable evolutionary origin. PMID- 4162778 TI - [Palliative treatment of serous effusions with radioactive gold Au-198]. PMID- 4162779 TI - Interactions between eye movements and the visually evoked response in the cat. PMID- 4162780 TI - [Prostatic hypertrophy]. PMID- 4162781 TI - [Mechanism of anaphylactic release of histamine from mast cells]. PMID- 4162782 TI - Oral contraceptives. PMID- 4162783 TI - [Intravitam staining of the causative agent of trichomoniasis in cattle]. PMID- 4162784 TI - Gm(20), a new hereditary gamma globulin factor. PMID- 4162785 TI - Gm and Inv studies of a Hokkaido population: evidence for a Gm2 allele in the Ainu. PMID- 4162786 TI - Chemotherapy for advanced ovarian cancer. PMID- 4162787 TI - Absorption of macromolecules by neonatal intestine. PMID- 4162788 TI - Colour reactions in chromatography. PMID- 4162789 TI - Alpha-2-anti-trypsin activity and different trypsin substrates. PMID- 4162790 TI - A comparison of dyes used for staining electrophoretically separated lipoprotein components. PMID- 4162791 TI - Differential staining of ceruloplasmin as an aid to interpretation in immunoelectrophoresis. PMID- 4162792 TI - [Initial trials with simultaneous rabies vaccination in man]. PMID- 4162793 TI - The prevention of ageing in cells. PMID- 4162794 TI - Metronidazole in amoebic dysentery and amoebic liver abscess. PMID- 4162795 TI - Faecal carriage of Pseudomonas aeruginosa in hospital patients. Possible spread from patient to patient. PMID- 4162796 TI - Death from appendicitis and appendicectomy. An epidemiological survey. PMID- 4162797 TI - Penicillamine for the treatment of Darier's disease and other disorders of keratin formation. PMID- 4162798 TI - The long-term value of fasting in the treatment of obesity. PMID- 4162799 TI - Plasma-testosterone levels in Kenyan men in relation to cancer of the nasopharynx. PMID- 4162800 TI - Clinical differentiation between primary and metastatic brain tumours. PMID- 4162802 TI - Accuracy of death certificates. PMID- 4162801 TI - A comparison of infra-red and convective heating for newborn infants. PMID- 4162803 TI - Brucellosis. PMID- 4162804 TI - Better members. PMID- 4162806 TI - Obesity in childhood. PMID- 4162805 TI - Dental erosion. PMID- 4162807 TI - Alcohol and the pancreas. PMID- 4162808 TI - Steroid treatment of asthmatic children. PMID- 4162809 TI - A method for the rapid determination of the number of patients to include in a controlled clinical trial. PMID- 4162810 TI - Mental deficiency no ground for divorce. PMID- 4162811 TI - [On the use of streptomycin combinations in general practice]. PMID- 4162812 TI - Synthesis of alpha-2-AP (acute phase) globulin of rat serum by the liver. PMID- 4162813 TI - Effect of antibiotics on some rumen and intestinal bacteria. PMID- 4162814 TI - Electroencephalographic changes in children with migraine. PMID- 4162815 TI - Thyroid hormone induction of alpha-glycerophosphate dehydrogenase in rats of different ages. PMID- 4162816 TI - Antithyroid action in rats of small doses of some naturally occurring compounds. PMID- 4162817 TI - Cirrhosis and prostatic neoplasms. PMID- 4162818 TI - Terminal patient care. PMID- 4162819 TI - The antagonism of the effects of compound 48-80 by protoveratrine A and piperacetazine. PMID- 4162820 TI - [On the problem of the treatment of gas gangrene]. PMID- 4162821 TI - Creating your own patient-education program with audio-visual materials. PMID- 4162822 TI - Vascular volume changes following histamine release in the dog forelimb. PMID- 4162823 TI - Hidden rheumatoid factors with specificity for native gamma globulins. PMID- 4162824 TI - A case of congenital insensitivity to pain with neuropathic arthropathy. PMID- 4162825 TI - Hexamethylentetramine-silver reaction for lysosomes. PMID- 4162826 TI - Demonstration of sarcoplasmic reticulum of skeletal muscle by hematoxylin. PMID- 4162827 TI - [Toxic adenoma of the thyroid gland. Study of 160 cases and review of the literature]. PMID- 4162828 TI - [A new application of the method of Champy-Maillet for detecting nerve fibers in thick microanatomic preparations of blood vessels injected with hematoxylin]. PMID- 4162829 TI - The relationship of juvenile hypothyroidism to chronic lymphocytic thyroiditis. PMID- 4162830 TI - Increase in source of vaccinia immune globulins. PMID- 4162831 TI - [Studies on orangephilia of some structures in glial tumors stained with polychromes]. PMID- 4162832 TI - On the possibility of selective staining of DNA and RNA using toluidine blue and related dyes. PMID- 4162833 TI - Studies on sarcoptic mange in camels (camelus dromedarius). PMID- 4162834 TI - The frequencies of transferrin types in the population of Cracow (Poland). PMID- 4162835 TI - [The local inflammatory reaction in the pyrexal skin test according to Heilmeyer in arterial blood circulation disorders in the region of the extremities]. PMID- 4162836 TI - [New data on the physiology and pathology of immunoglobulins]. PMID- 4162837 TI - The heptacarboxylic porphyrin of various types of porphyria and the melting-point curve of methyl esters of the 1 and 3 isomers. PMID- 4162838 TI - Exhibit advances community nutrition education. PMID- 4162839 TI - The effect of phenyramidol on the metabolism of bishydroxycoumarin. PMID- 4162840 TI - [A melanoblastoma]. PMID- 4162841 TI - [Electron microscopic study on hemagglutination produced by iodinized Coombs serum. (Preliminary report)]. PMID- 4162842 TI - [Morbidity in later age of premature infants having received large doses of gamma globulin]. PMID- 4162843 TI - [Thyroid function in spontaneous interruptions of pregnancy tested by protein bound iodine in blood plasma]. PMID- 4162844 TI - [Treatment of prostatic hypertrophy in persons over 70]. PMID- 4162845 TI - [The anti-pressor effect of heparins, heparinoids and SP-54 in hypertensive patients]. PMID- 4162846 TI - [Hemeran cream, a local antiphlebitic and antithrombotic agent]. PMID- 4162847 TI - Studies on sera from cases of myasthenia gravis, using the fluorescent antibody technique. PMID- 4162848 TI - Sequential estrogen and progestogen therapy. A clinical evaluation. PMID- 4162849 TI - Morphology of the cervix in women treated with synthetic progestins. PMID- 4162850 TI - Studies on the staining of amyloid with Congo red. PMID- 4162851 TI - Variation in membrane structure as revealed by negative staining technique. PMID- 4162852 TI - Modifications in the fluorescence microscopy technique as applied to identification of acid-fast bacilli in tissue and bacteriological material. AB - The principles and techniques involved in fluorescence microscopy as related to the demonstration of acid-fast bacilli are discussed. The auramine-rhodamine staining method, for both tissue and bacteriological preparations, is described as well as the necessary equipment for both microscopy and photomicroscopy. Fluorescence staining is no more difficult nor time consuming than a Ziehl Neelsen stain yet it is more effective in demonstrating acid-fast organisms. PMID- 4162853 TI - Cytological features of anthrax spores phagocytized in vitro by rabbit alveolar macrophages. PMID- 4162854 TI - [On the biochemical significance of mucopolysaccharides in wound healing and clinical experiences with Hirudal]. PMID- 4162855 TI - pH-changes in mercuric chloride solutions in contact with human and guinea pig skin, in vivo and in vitro. PMID- 4162856 TI - Some attempts to influence the percutaneous absorption rate of sodium (22Na) and mercuric (203Hg) chlorides in the guinea pig. Effect of soap, alkyl aryl sulphonate, stripping, and pretreatment with distilled water and mercuric chloride. PMID- 4162857 TI - Interaction between dithranol and nucleic acids. A possible mechanism for the effect of dithranol on psoriasis. PMID- 4162858 TI - Histamine induced increase of basophil and eosinophil leukocytes in inflammatory exudates. PMID- 4162859 TI - Dermatitis herpetiformis. Cases observed at the Dermatologic Clinic, Karolinska Sjukhuset, 1954--1963. PMID- 4162860 TI - Psoriasis: aetiological aspects. PMID- 4162861 TI - Ophthalmological changes in atopic dermatitis. PMID- 4162862 TI - Myotonia atrophica and multiple calcifying epithelioma of Malherbe. PMID- 4162863 TI - "Disappearance measurements", a method for studying percutaneous absorption of isotope-labelled compounds emitting gamma-rays. PMID- 4162864 TI - Percutaneous absorption of sodium chromate (51Cr), cobaltous (58Co), and mercuric (203Hg) chlorides through excised human and guinea pig skin. PMID- 4162865 TI - A non-specific effect of pollen distinguishable from the anaphylactic behaviour. PMID- 4162866 TI - The behavioural pattern of the non-specific reaction to pollen in comparison with reactions to histamine, compound 48-80, serotonin and bradykinin. PMID- 4162867 TI - Motor behaviour of actively sensitized guinea-pigs during the anaphylactic reaction. PMID- 4162868 TI - Skin homograft survival in thyroidectomized and thyroxin treated guinea-pigs. PMID- 4162869 TI - Immunologic studies in pathologic conditions of the skin, with special reference to psoriasis. PMID- 4162870 TI - Partial inhibition of the lupus erythematosus cell phenomenon by dexamethasone. PMID- 4162871 TI - Adhesive tape. Its bacteriostatic effect and its use in the treatment of ulcus cruris. PMID- 4162872 TI - The latex-histamine test in skin diseases. PMID- 4162873 TI - Microsporon canis--an actual cause of ringworm in Sweden. PMID- 4162874 TI - Fluorescence microscopy of acantholytic cells in primordial vesicles in chronic forms of eczema. PMID- 4162875 TI - Acute parapsoriasis with articular involvement. (Report of a case). PMID- 4162876 TI - [Histochemical studies on the polygonal cells of the rabbit cornea in tissue culture. 1. PAS-positive substances of the polygonal cells]. PMID- 4162877 TI - Congenital indifference to pain. PMID- 4162878 TI - Diagnosis of experimental fungal corneal ulcers by fluorescent antibody techniques. PMID- 4162879 TI - The temporal raphe of the human retina. PMID- 4162880 TI - Hair loss in patients treated with carbimazole. PMID- 4162881 TI - [Importance of experimental conditions in the evaluation of the activity of gestogens in the castrated rat after ovoimplantation]. PMID- 4162882 TI - A study of individual neuro-muscular junctions in myotonia. PMID- 4162883 TI - Motivational determinants of the "contingent negative variation". PMID- 4162884 TI - The phasic relation of a component of alpha rhythm to fixation saccadic eye movements. PMID- 4162885 TI - Some characteristics of stimulus-provoked alpha activity. PMID- 4162886 TI - Behavioral and polygraphic study of "sleep" and "wakefulness" in chronic decerebrate cats. PMID- 4162887 TI - Effects of anesthetics upon the EEG response to reticular stimulation. Patterns of slow synchrony. PMID- 4162888 TI - Ontogenesis of paroxysmal cortical activity in foetal sheep. PMID- 4162890 TI - The use of carbon electrodes for chronic cortical recording. PMID- 4162889 TI - Effects of an association between oxytocin and ACTH on the EEG and clinical evolution of some cerebral diseases. PMID- 4162891 TI - Histamine release in vivo during anaphylaxis in mice. PMID- 4162892 TI - [Histochemistry and ultrastructure of the cornea in a case of gargoylism]. PMID- 4162894 TI - Some aspects of wound healing in the germfree animal. PMID- 4162893 TI - Regeneration and Hyper-regeneration of corneal nerves. PMID- 4162895 TI - [Treatment of bronchial asthma and asthmatoid bronchitis with gamma globulin or epsilon aminocaproic acid]. PMID- 4162896 TI - The effects of polyamines on the melting of polyriboadenylic acid plus polyribouridylic acid complexes in a solution. PMID- 4162897 TI - [Immunologic aspects of the ataxia-teleangiectasia syndrome]. PMID- 4162899 TI - Landolt's club in the amphibian retina: a Golgi and electron microscope study. PMID- 4162898 TI - Clinical, histochemical, and electron microscopic study of colonic histiocytosis. PMID- 4162900 TI - Effect of central cooling in man on pituitary-thyroid function and growth hormone secretion. PMID- 4162901 TI - Mucoprotein-containing histiocytes (muciphages) in the rectum. AB - Mucoprotein-containing macrophages (muciphages) are a common finding in routine rectal biopsies, occurring in about 50% of cases. No correlation was found between their presence and the sex, age, and disease of the patient. They must be distinguished from the cells of Whipple's disease and from lipofuscin-containing macrophages. The origin of the mucoprotein is discussed and rectal epithelial mucin is considered a possible source. PMID- 4162902 TI - [Demonstration and ultrastructure of hepatic glycogen. The effect of technics on the preparation]. PMID- 4162903 TI - [On the problems of quantitative determination of tumor cells in blood]. PMID- 4162904 TI - Oral contraceptives. PMID- 4162905 TI - [On the therapy of Sudeck's disease]. PMID- 4162906 TI - Narcotic blockade--a medical technique for stopping heroin use by addicts. PMID- 4162907 TI - Atypical bacteria in Whipple's disease. PMID- 4162908 TI - [The treatment of pulmonary embolism and venous thrombosis with thrombolytic agents]. PMID- 4162909 TI - [Study of a case of IgD myeloma. (First Italian case)]. PMID- 4162910 TI - Simplified procedure for determining sensitivities of mastitis causing organisms to antibacterial agents. PMID- 4162911 TI - Pesticides--a dairy industry problem. PMID- 4162913 TI - Ichthyosporidium sp. Schwartz, 1963, parasite of the fish leiostomus xanthurus, is a microsporidian. PMID- 4162912 TI - Phytanic acid in Refsum's syndrome. PMID- 4162914 TI - [The modifications of the Michaelis constants of pepsins and trypsins by various irradiated proteins and the chromatographic and electrophoretic separation of the splitting products produced by proteolysis]. PMID- 4162915 TI - [The behavior of haptoglobins and Gm factors, as well as their relations to the quantitative alpha-2 and gamma globulin values in diseases of the blood]. PMID- 4162916 TI - [Viral hepatitis. Current epidemiological and practical problems]. PMID- 4162917 TI - [On the technic of block of the stellate ganglion]. PMID- 4162918 TI - Rules and regulations--Annual Award Committee. PMID- 4162920 TI - Third molar impactions: need for removal and care. PMID- 4162919 TI - Strike two. PMID- 4162921 TI - Radiography in crown and bridge prosthodontics. PMID- 4162922 TI - Accreditation program for dental laboratories. PMID- 4162923 TI - NADSP supports proposal for children's dental health program. PMID- 4162924 TI - [On antibodies following keratoplasty]. PMID- 4162925 TI - Studies on the livetins of egg yolk. 3. Heterogeneity and immunoelectrophoretic behavior of beta-livetin. PMID- 4162926 TI - Intracarotid amobarbital and metrazol test for the study of epileptiform discharges in man: a note on its technique. PMID- 4162927 TI - Peptide maps of rabbit gamma-G-immunoglobulin heavy chains controlled by allelic genes. PMID- 4162928 TI - Isoantibodies specific for myeloma gamma-G and gamma-H immunoglobulins of BALB-c mice. PMID- 4162929 TI - Some comments on Hoglund & Levin's electron micrographs of human serum proteins. PMID- 4162930 TI - Dihydrostreptomycin and kanamycin ototoxicity. An experimental study by surface preparation technique. PMID- 4162931 TI - Mechanism of antibody synthesis: size differences between mouse kappa chains. AB - Structural analysis of immunoglobulin light chains has been carried out in an attempt to elucidate the genetic mechanisms involved in antibody synthesis. Analysis of two mouse kappa-chain proteins is almost complete. The differences are localized in one-half of the molecules, and do not reflect the operation of any one mutational mechanism. The peculiar character of the differences is discussed with reference to various theories of antibody formation. The finding that the two proteins differ in size is incompatible with certain proposed theories. PMID- 4162932 TI - Granules and tubules in the cytoplasm of the sleeping sickness trypanosome: an electron microscope study. PMID- 4162933 TI - [Intravital staining of the central nervous system by diphenylthiocarbazone]. PMID- 4162934 TI - A new ward for infectious skin conditions in the dermatologic clinic of the Karolinska Hospital, Stockholm. PMID- 4162935 TI - Some immunological properties of guinea pig skin-saline suspension. I. Attempts to sensitize guinea pigs to homologous skin-suspension. PMID- 4162936 TI - Some immunological properties of guinea pig skin-saline suspension. II. Rabbit dermatotoxic serum. PMID- 4162937 TI - Spontaneous flare-up reactions induced by different amounts of 1,3-dinitro-4 chlorobenzene. Frequency of reactions, time of appearance and histology. PMID- 4162938 TI - Routine patch testing 3. Frequency of contact allergy at six Scandinavian clinics. PMID- 4162939 TI - Fluorescence microscopy of malignant melanomas in the Syrian golden hamster. PMID- 4162940 TI - The effect of roentgen irradiation on the specific fluorescence of epidermal melanocytes. PMID- 4162941 TI - High titer of Wassermann antibodies in a case of advanced myelomatosis. PMID- 4162942 TI - Vitamin A in the treatment of maleformatio ectodermalis generalisata--"porcupine man". PMID- 4162943 TI - Pigmentary disturbances due to drugs. PMID- 4162944 TI - A simple method for combined chemical and dermatological analysis of chemical mixtures by paper chromatography. PMID- 4162945 TI - Parameters of hemostasis in Epidermolysis bullosa: absence of significant deviations from normal. PMID- 4162946 TI - Tentative new classification of melanoma of the skin. PMID- 4162947 TI - Influence of vehicles on the topical activity of fluorometholone. PMID- 4162948 TI - Epidemic occurrence of trichophytosis among wrestlers. PMID- 4162949 TI - Cytomorphologic analyses of smears from the male urethra in urethritis of gonococcal and non-gonococcal origin. PMID- 4162950 TI - The essence of gonorrhoea control. IV. The promiscuous female pool. PMID- 4162951 TI - Phenobarbital and the shoulder-hand syndrome. PMID- 4162952 TI - [Morphological and physiologic changes of staphylococci under the influence of streptomycin and cobalt 60]. PMID- 4162953 TI - Classification of immunoglobulins in the dermal-epidermal junction in lupus erythematosus. PMID- 4162954 TI - Donovanosis. PMID- 4162955 TI - [Staining of schizomycetes with calcofluor white M2R. (2). Effect on the growth of the fluorescing bacteria]. PMID- 4162956 TI - The influence of thioridazine upon urinary gonadotropin excretion. PMID- 4162957 TI - Congenital agammaglobulinemia: a review. PMID- 4162958 TI - Patch test methods. II. Regional variations of patch test responses. PMID- 4162959 TI - Diagnostic importance of punch biopsy and cytologic examination in herpes zoster and herpes simplex. PMID- 4162960 TI - The character of cells with "alteration cavitaire" (Leloir). PMID- 4162961 TI - Report on a case of subcutaneous dissemination of Aspergillus niger, type awamori. PMID- 4162962 TI - Investigations of dermatophyte sensitivity to griseofulvin. PMID- 4162963 TI - Unusual cutaneous manifestations in Wegener's granulomatosis. PMID- 4162964 TI - Dermatitis in a crisp factory. PMID- 4162965 TI - Kinetics of glycolysis after fluocinolone acetonide in psoriasis. PMID- 4162966 TI - The essence of gonorrhoea control. I. The importance of "feed back". PMID- 4162967 TI - Recurrence of gonorrhoea following penicillin treatment. PMID- 4162968 TI - Etiological problems in connection with a case of Kaposi's varicelliform eruption. PMID- 4162969 TI - Coexistent chronic myelocytic leukemia, monoclonal gammopathy and multiple chromosomal abnormalities. PMID- 4162970 TI - Survival in males with bronchogenic carcinomas resected as asymptomatic solitary pulmonary nodules. PMID- 4162971 TI - Problems in surgery for bronchogenic carcinoma. PMID- 4162972 TI - [A rapid method of silver impregnation of nerve ganglia]. PMID- 4162973 TI - [Investigation on permanent long lasting storage of the color preparations of Treponema pallidum. II. Relation of the preliminary treatment with various fixatives and disinfectants]. PMID- 4162974 TI - Observations on the ultrastructure of the plasmalemma in oranges. PMID- 4162975 TI - Varicella-zoster infections in pregnancy. PMID- 4162976 TI - Rapid uptake of tritiated antigen by mouse eosinophils. PMID- 4162978 TI - Dynamics of protein-bound iodine of blood plasma in thyroid diseases. PMID- 4162977 TI - Chromatography, physical characteristics, and disulfide bonds of euglobulin plasminogen. PMID- 4162979 TI - The dose of antigen required for the suppression of the IgM and IgG antibody response in chickens. II. Studies at the cellular level. PMID- 4162980 TI - [Demonstrability of the nucleolus in the lymphatic elements of peripheral blood]. PMID- 4162981 TI - The mechanism of the differential staining reaction for adrenaline-and noreadrenaline-storing granules in tissues fixed in glutaraldehyde. PMID- 4162982 TI - The rheumatic diseases; laboratory procedures and diagnosis. PMID- 4162983 TI - Radiation therapy of lung cancer. Maine Medical Center, 1955-1965. PMID- 4162984 TI - [Treatment of Sudeck's syndrome with Reparil]. PMID- 4162985 TI - [A new method for differential staining of spores]. PMID- 4162986 TI - Myelopathy caused by metastatic spinal epidural neoplasms. PMID- 4162987 TI - Serum protein bound iodine and the ABO blood groups. PMID- 4162988 TI - Zymosan coated particles used to prepare anti-beta-1C. PMID- 4162989 TI - Detection of anti-gamma-globulin factors in human sera by simple screening methods. PMID- 4162991 TI - Some properties of the DNA-actinomycin K complex. PMID- 4162990 TI - The inhibitory effect of mouse gamma globulin on the lysis of isologous mouse tumour cells by human serum. PMID- 4162992 TI - Effect of actinomycin D on alkaline phosphatase induction by estrogen in uterine epithelium of spayed mice. PMID- 4162993 TI - Serum-protidopoyesis in neonatally thymectomized rats develops normally. PMID- 4162994 TI - Studies on the passage of virus and antibody-protein through the human placenta. A fluorescence-microscopic observation. PMID- 4162995 TI - [On the technique of medical lectures]. PMID- 4162996 TI - [Studies on anti-Gm antibodies in sera of patients with rheumatoid arthritis and in sera of normal individuals]. PMID- 4162997 TI - [Proportional increase of gamma globulins in normal cerebrospinal fluid in routine tests. Observations made with paper electrophoresis]. PMID- 4162998 TI - Hyperthyroidism causing atrial fibrillation in a young man. PMID- 4163000 TI - [Amino acid composition of thyroglobulin from euthyroid and goitrous subjects]. PMID- 4162999 TI - Typical and atypical cases of Pendred's syndrome in one family. PMID- 4163001 TI - The goitrogenic effect of naturally occurring L-5-vinyl- and L-5-phenyl-2-thio oxazolidone in rats. PMID- 4163002 TI - Intravenous administration of modified gamma globulin. Several studies on a patient with agammaglobulinemia. PMID- 4163003 TI - Quantitation of immunoglobulins in cerebrospinal fluid. PMID- 4163005 TI - [On the stainability and non-stainability of Entamoeba histolytica with eosin]. PMID- 4163004 TI - [The Kohn chlorazol technic for staining protozoa]. PMID- 4163006 TI - The use of a wate-soluble carbodiimide as a coupling reagent in the passive hemagglutination test. PMID- 4163007 TI - "Protein A" from S. aureus. I. Pseudo-immune reaction with human gamma-globulin. PMID- 4163008 TI - Physicochemical properties of reaginic antibody. V. Correlation of reaginic activity wth gamma-E-globulin antibody. PMID- 4163009 TI - The interaction of antigen with leucocytes of allergic individuals. PMID- 4163010 TI - Effects of mild eriodate oxidation on antibodies. PMID- 4163011 TI - The sedimentation and antigenic properties of proteins in nasal and other external secretions. PMID- 4163012 TI - Adoptive cutaneous anaphylaxis: a technique for studying antibody globulin synthesis. PMID- 4163013 TI - Isolated thyroid-stimulating hormone (TSH) deficiency following childbirth. PMID- 4163014 TI - [Studies on staining properties of the striated muscle and myocardium]. PMID- 4163015 TI - Mouse immunoglobulin allotypes: detection with rabbit antiserums. AB - An antiserum with allotypic specificity for mouse gamma(2a)-globulins was prepared in a rabbit by injection of 7S gamma(2)-globulin of C(57)BL/6 mice. The antibody reacted with an isoantigen in the 7S gamma(2)-globulins of normal serum of mouse strains belonging to the lg-1(b) allotype class (C(57)BL/6, C(57)BL/10, and SJL strains). No precipitin reaction was observed with serum from 18 other inbred mice strains representing other lg-1 allotype classes. PMID- 4163016 TI - [7-chlor and 7-brom-actinomycin]. PMID- 4163017 TI - An appraisal of the clinical effect of three different oral contraceptive agents and their influence on transaminase activity. PMID- 4163018 TI - Schizophrenia as an immunologic disorder. II. Effects of serum protein fractions on brain function. PMID- 4163019 TI - Schizophrenia as an immunologic disorder. I. Demonstration of antibrain globulins by fluorescent antibody techniques. PMID- 4163020 TI - The effect of osmium fixation on the histological appearance of the normal epidermal horny layers of man and the guinea-pig. PMID- 4163021 TI - [Actinocinyl-bis-peptide]. PMID- 4163022 TI - [Blocking action of beta-2A-globulin in certain cutaneous allergic reactions]. PMID- 4163023 TI - [Separation of a subcellular fraction enriched with acridine orange cytoplasmic granules]. PMID- 4163024 TI - [Actinomycin D as an in vivo dye and fluorochrome]. PMID- 4163025 TI - [The effect of mitomycin C, actinomycin C and puromycin on the synthesis of protein in cell strains obtained from human tumors]. PMID- 4163026 TI - Cytophotometric study of acid dye binding by proteins of isolated frog liver nuclei in relation to nuclear size. PMID- 4163027 TI - [Experiences with Feulgen staining for quantitative cytochemical determinations of DNA]. PMID- 4163028 TI - [Use of the microautoradiographic method for the study of the functional properties of the erythroid elements]. PMID- 4163030 TI - [On the reaction of the urine of cancer patients with methylene blue]. PMID- 4163029 TI - [On the value of determination of agranulocytes and use of fluorescent and immunologic tests in hematology]. PMID- 4163031 TI - [Experience in the use of the cytological method of study for the diagnosis of cancer. (According to data of the Saratov Regional Oncologic Clinic)]. PMID- 4163032 TI - [On the diagnostic value of Khakim's serological reaction in cancer]. PMID- 4163033 TI - [Influence of air temperature variations on the erythrocyte sedimentation reaction]. PMID- 4163034 TI - [On agglomerin (critical analysis of 1 concept)]. PMID- 4163035 TI - [On a method of duodenal intubation]. PMID- 4163036 TI - [A spectrographic method of determination of trace elements in human individual erythrocyte fractions and blood plasma]. PMID- 4163037 TI - [The isolation of hyaluronic acid and its chemical characteristics]. PMID- 4163038 TI - [On a method of determination of glutamine transaminase in the blood serum]. PMID- 4163039 TI - [The diagnostic value of quinine oxidase in Botkin's disease]. PMID- 4163040 TI - [On certain peculiarities of the determination of the fibrinolytic properties of the blood by Bidwell's method]. PMID- 4163041 TI - [Rapid methods of determination of diastase in the blood]. PMID- 4163042 TI - [A method of quantitative determination of the decarboxylase activity of bacteria of the Enterobacteriaceae family]. PMID- 4163043 TI - [On the presence of nitrate- and nitrite-reductase in different strains of Mycobacterium tuberculosis]. PMID- 4163044 TI - [Comparative evaluation of methods of measuring the drug resistance of Mycobacterium tuberculosis]. PMID- 4163045 TI - [On the significance of drug resistance of the causal agent for the clinical aspects of tuberculosis]. PMID- 4163046 TI - [On a method of electrophoretic detection of Mycobacterium tuberculosis in the sputum of pulmonary tuberculosis patients]. PMID- 4163047 TI - [Must Mycobacterium tuberculosis be detected in a blood-stained expectoration?]. PMID- 4163048 TI - [Automatic apparatus for decanting cell suspensions and nutritive media]. PMID- 4163049 TI - Acute pancreatitis associated with frusemide therapy. PMID- 4163050 TI - Agranulocytosis after desipramine. PMID- 4163051 TI - Reaction after dichloralphenazone. PMID- 4163052 TI - Jaundice and oral contraceptive drugs. PMID- 4163053 TI - Endocrine activity in multiple sclerosis. PMID- 4163054 TI - Secretion of gastric intrinsic factor. PMID- 4163055 TI - Effect of phenylhydrazine-induced haemolysis on the urinary excretion of iron after desferrioxamine. PMID- 4163056 TI - Prognosis in optic neuritis related to age. PMID- 4163058 TI - Low butanol-extractable-iodine levels in the serum of patients with Down's syndrome. PMID- 4163057 TI - Prevention of tetanus by antitoxin of bovine origin. PMID- 4163059 TI - Intrinsic-factor antibody in the saliva of a patient with pernicious anemia. PMID- 4163060 TI - Acute hemodynamic changes during treatment of louse-borne relapsing fever. PMID- 4163061 TI - Skin sensitivity to flour in bakers' apprentices. PMID- 4163062 TI - Hormones and histones? PMID- 4163063 TI - Hyperuricaemia, hypertension, and vascular disease. PMID- 4163064 TI - The primary physician in a comprehensive health service. Further reflections after a visit to the United States. PMID- 4163065 TI - A surgical wound isolator. PMID- 4163066 TI - [Intestinal lipodystrophy. (Whipple's disease)]. PMID- 4163067 TI - Inhibition of ovulation in the adult estrus rabbit by vaginal deposition. PMID- 4163068 TI - [Comparison between allergic rhinitis and bronchial asthma evaluated by the action histamine-liberating substances on the bronchi and nasal mucosa]. PMID- 4163069 TI - Systemic (primary) amyloidosis associated with an IgM (beta-2M) paraproteinaemia. Biochemical, histochemical and immunohistochemical investigations. PMID- 4163070 TI - Heterogeneity of anti-antibodies in individual human sera. PMID- 4163071 TI - The immune response to vaccination with inactivated poliovirus vaccine in Sweden. PMID- 4163072 TI - An improved procedure for the determination of serum protein-bound iodine by alkaline incineration. PMID- 4163073 TI - Staining for nerve fiber and cholinesterase activity in fresh frozen sections. PMID- 4163074 TI - An improved stain for fresh, mineralized bone sections. Useful in the diagnosis of certain metabolic diseases of the bone. PMID- 4163075 TI - [Staining of Entamoeba histolytica with fuchsin and methylene blue on histological slices]. PMID- 4163076 TI - LSD and the dying patient. PMID- 4163077 TI - [Comparative immunoelectrophoretic demonstration of gamma-alpha-globulin in agar and agarose]. PMID- 4163078 TI - Innervation of human finger tendons as determined by histochemical techniques. PMID- 4163079 TI - Electrophoretic analysis of serum proteins, glucoproteins and lipoproteins in acute infectious diseases in infants and children. PMID- 4163080 TI - [On the isolation of human gamma globulin fragments formed after splitting and their properties]. PMID- 4163081 TI - [Intubation in cancer of the gastro-intestinal anastomosis]. PMID- 4163082 TI - [Some notes on the nature of "nonspecific" gamma globulins]. PMID- 4163083 TI - [On the tissue nature of the so-called alveolar soft tissue sarcoma]. PMID- 4163084 TI - Recovery of the long-acting thyroid stimulator from serum of patients with thyrotoxicosis by concentration of immunoglobulin G. PMID- 4163085 TI - Pancreatic catabolism of albumin and gamma-globulin. PMID- 4163086 TI - Comparison of the behaviour of IgG and IgM anti-Forssman antibodies in agglutination, haemolysis and cytolysis. PMID- 4163087 TI - Atrial fibrillation: anticoagulation and quinidinization. PMID- 4163088 TI - [The level of neutral 17-ketosteroids in prostatic hypertrophy]. PMID- 4163089 TI - Neuropathic fractures and joint injuries. Pathogenesis and rationale of prevention and treatment. PMID- 4163091 TI - [On a new dynamic electrocardiographic procedure for long-term observation of the heart]. PMID- 4163090 TI - Canine scabies in dogs and in humans. PMID- 4163092 TI - Fluorescent treponemal-antibody absorption tests. Studies of false-positive reactions to tests for syphilis. PMID- 4163093 TI - [Actinomycin derived from dihydro-actinomycin]. PMID- 4163094 TI - Caries-like lesions in rat calculus. PMID- 4163095 TI - Nasal drops and sprays. PMID- 4163096 TI - New psychiatric unit at Bridgewater Hospital, Manchester. PMID- 4163097 TI - How drugs act. 5. Drugs and the thyroid gland. PMID- 4163098 TI - [The so-called periodic disease]. PMID- 4163099 TI - [The current status of fibrinolytic therapy]. PMID- 4163100 TI - [Cardiac catheterization. 1. Technic]. PMID- 4163101 TI - [Typhoid fever]. PMID- 4163102 TI - [Sterilization: methods--controls]. PMID- 4163103 TI - [What is the situation in the state hospitals?]. PMID- 4163104 TI - [The demographic occurrence of birth control in France]. PMID- 4163105 TI - [Basal metabolism]. PMID- 4163106 TI - [Nursing in the treatment of myocardial infarct]. PMID- 4163107 TI - Schizophrenia as an immunologic disorder. 3. Effects of antimonkey and antihuman brain antibody on brain function. PMID- 4163108 TI - The organization of the ventral anterior nucleus of the thalamus. A Golgi study. PMID- 4163109 TI - The posterior thalamic region in man. PMID- 4163110 TI - [The antitumoral and toxic effect of individual aurantins (actinomycins)]. PMID- 4163111 TI - [Precipitation of protein fractions from serum by chlorpromazine]. PMID- 4163112 TI - The pathogenesis of postobstructive diuresis. PMID- 4163113 TI - An immunoelectrophoretic study of the soluble antigens of the human prostate. PMID- 4163114 TI - Radioactive phosphorus in the treatment of metastasis to bone from carcinoma of the prostate. PMID- 4163115 TI - [On a method of obtaining pure gastric juice]. PMID- 4163116 TI - [On a modified method of determination of estriol in the urine of pregnant women]. PMID- 4163117 TI - [On the microbiological examination of cadavers]. PMID- 4163118 TI - Propranolol and hypoglycaemia. PMID- 4163119 TI - John Josias Conybeare. PMID- 4163120 TI - Glucose tolerance in hypertensive patients on long-term diuretic therapy. PMID- 4163121 TI - The blind-loop syndrome. PMID- 4163122 TI - An immunological study of categories of gastritis. PMID- 4163123 TI - Relation of residual placental blood-volume to onset of respiration and the respiratory-distress syndrome in infants of diabetic and non-diabetic mothers. PMID- 4163124 TI - Acid secretion in symptomatic sliding hiatus hernia. PMID- 4163125 TI - Renal failure in malaria. PMID- 4163127 TI - A pneumothorax valve. PMID- 4163126 TI - Agglutination of tanned sheep erythrocytes by serum from Nigerian adults and children. PMID- 4163128 TI - Effect of interstitial pressure on pulmonary blood-flow. PMID- 4163129 TI - Lymphocyte stimulation and chronic liver disease. PMID- 4163131 TI - The mortality of appendicitis. PMID- 4163132 TI - Barbiturate poisoning. PMID- 4163130 TI - Cushing's syndrome: use of lysine vasopressin to distinguish overproduction of corticotrophin by pituitary from other causes of adrenal cortical hyperfunction. PMID- 4163133 TI - A parting gift. PMID- 4163134 TI - Preventing misuse of L.S.D. PMID- 4163135 TI - Veratrum and myasthenia gravis. PMID- 4163136 TI - Local government. PMID- 4163137 TI - Fluorides and osteoporosis. PMID- 4163138 TI - Diabetic neuropathy. PMID- 4163139 TI - Outpatient treatment of heroin addiction. PMID- 4163140 TI - Some aspects of current therapy in acute leukemia. PMID- 4163141 TI - Vinca alkaloids and salivary-gland pain. PMID- 4163142 TI - Prevalence and pathological changes of ischaemic heart-disease in a hard-water and in a soft-water area. PMID- 4163143 TI - Serum protein and cholinesterase changes in association with contraceptive pills. PMID- 4163145 TI - Tryptophan metabolism in carcinoma of the breast. PMID- 4163144 TI - Parietal-cell antibodies in patients with duodenal ulcer and gastric cancer. PMID- 4163146 TI - Cellular metachromasia, a genetic marker for studying the mucopolysaccharidoses. PMID- 4163147 TI - Bacteriological findings in acute otitis media. PMID- 4163148 TI - Role of carriers in the intrafamilial spread of cholera. PMID- 4163149 TI - Active renal water excretion. PMID- 4163150 TI - An immunosupressive site of action of heterologous antilymphocyte serum. PMID- 4163151 TI - Central and peripheral effects of anti-lymphocyte sera. PMID- 4163152 TI - Relation between haemagglutination by immunoglobulin-A preparations and reaginic activity. PMID- 4163153 TI - R-factor-mediated resistance to new aminoglycoside antibiotics. PMID- 4163154 TI - Haemochromatosis and hepatic xanthine oxidase. PMID- 4163155 TI - Human growth hormone and insulin. PMID- 4163157 TI - Action needed on epilepsy. PMID- 4163156 TI - Endotracheal intubation or tracheostomy? PMID- 4163158 TI - Rubella vaccines. PMID- 4163159 TI - The 1967 outbreak of influenza B in the U.S.S. R. PMID- 4163160 TI - Lead poisoning from drinking soft water. PMID- 4163161 TI - Osmometry. PMID- 4163162 TI - The rationale of oxygen therapy. PMID- 4163163 TI - [Parameters of evaluation of balneotherapy in children with rheumatoid arthritis. 3. Serologic studies]. PMID- 4163164 TI - [Endoscopy and audio-visual education]. PMID- 4163165 TI - Vulnerability of the organ of Corti in poisoning. PMID- 4163166 TI - The histochemistry of mucins in certain primate salivary glands. PMID- 4163167 TI - Further observations on the cutaneous branches of the dorsal primary rami of the spinal nerves. PMID- 4163168 TI - Serum and bile lipids in altered thyroid function. PMID- 4163169 TI - Evaluation of palliative operations for carcinoma of the pancreas. PMID- 4163170 TI - Rupture of small ducts and acini in the pancreas of the rat and guinea pig following major duct obstruction. PMID- 4163171 TI - The anticoagulant response to bishydroxycoumarin. I. The role of individual variation. PMID- 4163172 TI - The anticoagulant response to bishydroxycoumarin. II. The effect of D-thyroxine, clofibrate, and norethandrolone. PMID- 4163173 TI - Plutonium inhalation studies. VII. Bronchiolo-alveolar carcinomas of the canine lung following plutonium particle inhalation. PMID- 4163175 TI - Histamine release from leukocytes of hypersensitive individuals. II. Reduced sensitivity of leukocytes after injection therapy. PMID- 4163174 TI - A factor in pollen which enhances vascular permeability. PMID- 4163176 TI - Studies on the placental transfer of skin-sensitizing antibody, specific binding of a ragweed fraction, and immunoglobulins. PMID- 4163177 TI - Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test. PMID- 4163178 TI - Early secretory activity in the hypothalamic nuclei and neurohypophysis in the rat; determined by selective staining. PMID- 4163179 TI - The cellular localisation of growth hormone in the human foetal adenohypophysis. PMID- 4163180 TI - Antigen-induced morphological changes in germ-free mice. PMID- 4163181 TI - Influence of cold on thyroid uptake of iodine-131 and circulating iodine compounds. PMID- 4163182 TI - Separation of 2 different substrates for plasma kinin-forming enzymes. PMID- 4163183 TI - [Transurethral prostatectomy for prostatic calculi]. PMID- 4163184 TI - Application of systems concepts to instruction. PMID- 4163185 TI - Synthesizing language arts skills with the overhead projector. PMID- 4163186 TI - A multi-faceted approach to teaching. PMID- 4163187 TI - A multi-media approach in the classroom for the deaf. PMID- 4163188 TI - Effect of sequential mestranol-chlormadinone on sebum production. PMID- 4163189 TI - [On the physico-chemical peculiarities and antigenic activity of separate fragments of human gamma globulin obtained by ultrasonic effect]. PMID- 4163190 TI - Fibrillar structures ("cell web") in the cells of human adenocarcinomas. PMID- 4163191 TI - Low radioiodine uptake and high serum PBI levels from hemorrhage into thyroid adenoma. PMID- 4163192 TI - The surface reactions associated with fertilization of the sea urchin egg as studied by immunoelectron microscopy. PMID- 4163193 TI - Hemangiopericytoma. Report of a case. PMID- 4163194 TI - Osseous healing in dog mandibles with and without decortication. PMID- 4163195 TI - Cell renewal in the oral mucosa and skin of the rat. II. DNA conservation and reutilization during the renewal cycle in vivo and in tissue explants. PMID- 4163197 TI - Post ovulatory development of ovarian follicles in the domestic fowl. PMID- 4163196 TI - A cytochemical examination of the spermatozoon of the domestic fowl. PMID- 4163198 TI - The relative susceptibility of sheep, goats and mice to two types of the goat scrapie agent. PMID- 4163199 TI - The clinical significance of the immunoglobulins. PMID- 4163200 TI - [Effects of cobalt on thyroid function]. PMID- 4163201 TI - Inhibition of ovulation by estrogens. PMID- 4163202 TI - The presence of phytanic acid in normal human and animal plasma. PMID- 4163203 TI - The existence of an alternative pathway for the degradation of branch-chained fatty acids, and its failure in heredopathia atactica polyneuritiformis (Refsum's disease). PMID- 4163204 TI - Passive immunization with gamma globulin. PMID- 4163205 TI - The amino-terminal amino acid sequences of rabbit immunoglobulin light chains. PMID- 4163206 TI - Immunoglobulin levels in cord-blood serum of negroes and Caucasians. PMID- 4163207 TI - Imitation, modeling, and cross-cultural training. AMRL-TR-66-88. PMID- 4163208 TI - Contact allergy to wool-fat ("lanolin"). Its incidence in a dermatological in patient department. PMID- 4163209 TI - An electron microscopic study of the keratinization process in lichen ruber lesions. PMID- 4163210 TI - The pathogenesis of eczematous sensitization. PMID- 4163211 TI - The role of keratohyalin material in the keratinization process and its importance for the barrier function. PMID- 4163212 TI - Metabolic evaluation of the crural blood flow during standing and during sitting leg exercise in patients with congenital absence of venous valves in the legs. PMID- 4163213 TI - Erythema chronicum migrans with multiple lesions. PMID- 4163214 TI - Alopecia mucinosa and hypopituitarism. PMID- 4163215 TI - Kaposi's sarcoma associated with Hodgkin's disease. PMID- 4163216 TI - Urinary hydroxyproline in various diseases. PMID- 4163217 TI - Fluocinolone-plastic treatment and traditional treatment in severe psoriasis. A comparative study. PMID- 4163218 TI - The use of desoxycorticosterone acetate (DOCA) in the management of pemphigus. PMID- 4163219 TI - The demonstration of N. gonorrhoeae with the aid of fluorescent antibodies. 5. A comparison of different techniques--absorption, one-step inhibition, and counterstaining--for elimination of cross reactions. PMID- 4163220 TI - The demonstration of N. gonorrhoeae with the aid of fluorescent antibodies. 6. A comparison of conventional methods and fluorescent antibody (FA) techniques with counterstaining for the demonstration of N. gonorrhoeae. PMID- 4163221 TI - Sensitization to cobalt and nickel in cement eczema. PMID- 4163222 TI - Patch test methods. I. A comparative study of six different types of patch tests. PMID- 4163223 TI - Occupational quinidine contact dermatitis, a concept apparently not yet described. PMID- 4163224 TI - Bacterial allergy in the skin diseases. II. Delayed allergy to streptococci in some skin diseases. PMID- 4163225 TI - Problems in diagnosis, treatment and control of gonorrheal infections. I. A comparison of direct microscopy and culture. PMID- 4163226 TI - Biologic false positive seroreactions for syphilis. PMID- 4163227 TI - Treatment of non-gonococcal urethritis with tetracycline-L-methylene lysine. PMID- 4163228 TI - Transient kryoglobulinaemia. PMID- 4163229 TI - Comparison of various culture media for dermatophytes. PMID- 4163230 TI - Why Acarus scabiei avoids the face. PMID- 4163231 TI - Cellular changes in the psoriatic epidermis. II. The submicroscopic organization in psoriatic lesions of different age. PMID- 4163232 TI - A method for studying percutaneous toxicity of metal compounds in the guinea pig. PMID- 4163233 TI - Autologous skin grafting in psoriasis. Observations in the first postoperative weeks. PMID- 4163234 TI - The question of congenital keratoses. PMID- 4163235 TI - Use of polarising microscopy in the study of hair penetration by Trichophyton mentagrophytes. PMID- 4163236 TI - Studies of the mechanism of ultra-violet erythema formation. The role of histamine and histidine. PMID- 4163237 TI - Subcorneal pustular dermatosis. An immunoelectrophoretic study. PMID- 4163238 TI - Influence of polymyxin B and histamine on the cellular exudate in "skin windows". PMID- 4163239 TI - Bound hexose of the serum in scleroderma. PMID- 4163240 TI - The effect of chloroquine on glucose metabolism in erythrocytes of patients with chronic lupus erythematosus. PMID- 4163241 TI - The pathogenesis of the so-called ulcus vulvae acutum. PMID- 4163242 TI - Problems in diagnosis, treatment and control of gonorrheal infections. II. Routine sensitivity tests with the plate dilution and disc methods. PMID- 4163243 TI - Problems in diagnosis, treatment and control of gonorrheal infections. 3. The concentration of penicillin in the blood of men and women, respectively, with different doses and makes of penicillin. PMID- 4163244 TI - Problems in diagnosis, treatment and control of gonorrheal infections. IV. The correlation between the dose of penicillin, concentration in blood, IC-50-values of gonococci and results of treatment. PMID- 4163245 TI - [Histological and histochemical observations on the basal membrane in periodontal cysts]. PMID- 4163246 TI - Effects of thyrotrophic hormone on thyroid cells in filter-well culture. PMID- 4163248 TI - [Pharmaceutical studies with diene-addition products. V. On the coronary dilator properties of a new class of amines]. PMID- 4163247 TI - Pyridine nucleotides in the thyroid gland. VII. Effect of thyroid stimulating hormone on ATP concentration in dog thyroid slices. PMID- 4163249 TI - Histamine release by passive sensitization with murine neoplastic mast cells in vitro. PMID- 4163250 TI - Electroencephalographic changes during long term treatment with oral contraceptives. PMID- 4163251 TI - A histochemical study of the development of alkaline phosphatase in the testicle and epididymis of young bovine males. PMID- 4163252 TI - The effect of active and inactive rheumatoid factors on tolerance to human gamma globulin in Swiss mice. PMID- 4163253 TI - Serum immunoglobulin levels in human malaria and their relationship to antibody production. PMID- 4163254 TI - Immunoglobulin isoantigens (allotypes) in the mouse. 3. Detection of allotypic antigens with heterologous antisera. PMID- 4163255 TI - PCA and RPCA in guinea pigs with rabbit and guinea pig antibodies and different antigens. PMID- 4163256 TI - [On the laboratory diagnosis of prethrombotic states in the clinical aspects of internal diseases]. PMID- 4163257 TI - [On methods of determining the contact activation of blood coagulation]. PMID- 4163258 TI - [Xanthoma cells in bone marrow punctates and their diagnostic significance]. PMID- 4163259 TI - [On a method of intravital morphological study of immunogenetic intensity in rabbits]. PMID- 4163260 TI - [A method of study of the phagocytic reaction of blood neutrophil leukocytes in small laboratory animals]. PMID- 4163261 TI - [A micromethod of determination of the concentration of proteins by the xanthoprotein reaction]. PMID- 4163262 TI - [Comb-type nozzle arrangement for vacuum distillation]. PMID- 4163264 TI - [Elimination of the influence of variations in sodium level in the determination of potassium by the flame photometry method]. PMID- 4163263 TI - [Determination of lactate dehydrogenase activity as a method of diagnosis of bacterial endocarditis]. PMID- 4163265 TI - [Use of ion exchange resins for obtaining water equivalent to distilled water]. PMID- 4163266 TI - [On determination of the virulence of pyogenic staphylococci in chick embryos]. PMID- 4163267 TI - [Evaluation of methods of the bacteriological diagnosis of purulent meningitis]. PMID- 4163268 TI - [The diagnosis of Wolhynian riccketsiosis by the complement fixation test]. PMID- 4163269 TI - [An apparatus for the objective evaluation of the luminescence of microorganisms]. PMID- 4163270 TI - [Petri dishes of methyl polymethacrylate for tissue culture]. PMID- 4163271 TI - [A simplified apparatus for the incineration of materials by nitric acid vapors]. PMID- 4163272 TI - [Use of an automatic syringe in laboratory work]. PMID- 4163273 TI - [A small gauge exchange cage for small laboratory animals]. PMID- 4163274 TI - [The peripheral blood picture of "August" strain rats]. PMID- 4163275 TI - The sequential development of lesions in spontaneous Aleutian disease of mink. PMID- 4163276 TI - [Hyper-gamma-globulinemia in paper electrophoresis: its importance in clinical practice outside of myelomatous syndromes]. PMID- 4163277 TI - [On some immunological aspects of sarcoidosis]. PMID- 4163278 TI - Dysimmunoglobulinemia in the absence of clinical features of multiple myeloma and macroglobulinemia. PMID- 4163279 TI - Study of mesenteric lymph nodes in neonatally thymectomized rats with regard to cell types and gamma globulin content of cells. PMID- 4163280 TI - Psychotic episodes associated with the use of common proprietary decongestants. PMID- 4163281 TI - Treatment of carcinoma of the esophagus. PMID- 4163282 TI - Pancreaticoduodenal cancer. PMID- 4163283 TI - Refsum's disease--a recently characterized lipidosis involving the nervous system. Combined clinical staff conference at the National Institutes of Health. PMID- 4163284 TI - [Immunochemical analysis of the products of bovine gamma-globulin digestion with papain]. PMID- 4163285 TI - [Conditions favoring the onset of auricular fibrillation]. PMID- 4163286 TI - Endergonic reduction of mitochondrial diphosphopyridine nucleotide by sarcosine. PMID- 4163287 TI - Anticomplementary activity of sera from patients with connective tissue disease and normal subjects. PMID- 4163288 TI - [The demonstration and identification of a factor of the nature of immune globulin M and the antibody properties in the serum of patients with multiple sclerosis]. PMID- 4163289 TI - [Studies on the phytol metabolism in lipoidosis heredopathia atactica polyneuritiformis (Refsum's syndrome). The transformation of 3H-phytol into the 3,7,11,15-tetramethylhexadecanoic acid (phytanic acid) of the plasma lipoid fractions]. PMID- 4163290 TI - [The optic-polarization method of study of urinary calculi]. PMID- 4163291 TI - [Quantitative polarographic determination of microconcentrations of p phenylenediamine and benzidine]. PMID- 4163293 TI - [On a method of bilirubin determination (according to Jendrassik, Cleghorn and Grof)]. PMID- 4163292 TI - [Spectrophotometric method of determination of the amount of blood loss during labor]. PMID- 4163294 TI - [Determination of disulfide bonds in proteins]. PMID- 4163295 TI - [Determination of iodine bound to blood proteins]. PMID- 4163296 TI - [Determination of chlorine in the blood serum by use of a dichlorfluorescein indicator]. PMID- 4163297 TI - [Use of a meat-agar medium for cultivation of pertussis bacilli]. PMID- 4163298 TI - [A rapid method of laboratory diagnosis of colienteritis]. PMID- 4163299 TI - [Modification of a method of negative impression of the capsule]. PMID- 4163300 TI - [Statistical augmentation of the optimal conditions for calculation of the cells in a monolayer culture]. PMID- 4163301 TI - [A wide diapason apparatus for high-frequency titration without contact]. PMID- 4163302 TI - [A multiple layer support for coloring electrophoregrams]. PMID- 4163303 TI - [An apparatus for the cages of laboratory animals for the purpose of better utilization of their food]. PMID- 4163304 TI - [New model of a bacteriological batometer]. PMID- 4163305 TI - [A standard light apparatus for determination of the dimensions of the 3d blood coagulation fraction x]. PMID- 4163306 TI - [Improvement of the procedure of washing Petri dish test sets]. PMID- 4163307 TI - [Determination of the residual humidity of lyophylized preparations in a vacuum drying cabinet]. PMID- 4163308 TI - Acceleration of wound healing in man with zinc sulphate given by mouth. PMID- 4163310 TI - Urinary excretion of free noradrenaline and adrenaline following acute myocardial infarction. PMID- 4163309 TI - A critical evaluation of the trisodium-edetate test for hypo-parathyroidism after thyroidectomy. PMID- 4163311 TI - Treatment of urinary schistosomiasis. Practice and theory. PMID- 4163313 TI - Bacillus cereus bacteraemia. A complication of intermittent haemodialysis. PMID- 4163312 TI - Assessment of body-iron stores in cirrhosis and haemochromatosis with the differential ferrioxamine test. PMID- 4163314 TI - Glucose-6-phosphate-dehydrogenase deficiency, sickling, and malaria in African children in South Western Nigeria. PMID- 4163315 TI - Isolation of diphtheroid organisms from rheumatoid synovial membrane and fluid. PMID- 4163316 TI - Psychiatric aspects of cerebrovascular disease. PMID- 4163318 TI - Notes towards the definition of education. A personal account of the Plowden Committee. PMID- 4163317 TI - Poverty and the welfare state. PMID- 4163319 TI - Trials and tribulations. PMID- 4163320 TI - Subnormality and unsoundness of mind. PMID- 4163321 TI - Propranolol and hypoglycemia. PMID- 4163322 TI - Denis John Wolko Browne. PMID- 4163323 TI - Possibility of a new infective aetiological agent in congestive cardiomyopathy. PMID- 4163324 TI - The effect of cryoprecipitate concentrate in patients with classical haemophilia. PMID- 4163325 TI - Isoenzymes of alkaline phosphatase in patients operated upon for peptic ulcer. PMID- 4163326 TI - Bassen-Kornzweig and Refsum's syndromes. Some comments on their recognition among the N.Z. population. PMID- 4163327 TI - Anticoagulant therapy of cerebral infarction: report of a national cooperative study. PMID- 4163328 TI - A long term study of cerebral vascular disease. PMID- 4163329 TI - Evaluation of anticoagulant therapy in focal ischemic cerebrovascular disease: further observations. PMID- 4163330 TI - Prostatectomy in the community hospital. PMID- 4163331 TI - [Significance of the Nissl technique in the study of structural disorders of the central and peripheral nervous system]. PMID- 4163332 TI - [Sensitization of formalinized erythrocytes by immune gamma-globulins]. PMID- 4163333 TI - Palliative treatment of Ewing's sarcoma. PMID- 4163334 TI - The immunoelectrophoretic gamma-A globulin in malabsorption. PMID- 4163335 TI - [The production of embryo-specific alpha-globulin in dogs during the intrauterine period and in the first days after birth]. PMID- 4163336 TI - Nerve-muscle relations in the salamander: possible relevance to nerve regeneration and muscle specificity. PMID- 4163337 TI - [Auditive and perceptive education]. PMID- 4163338 TI - A new method for preparing staining solutions for bacteriological examinations. PMID- 4163339 TI - Dentine caries. PMID- 4163340 TI - The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation. PMID- 4163341 TI - Inhibition of the anti-globulin reaction by nonspecifically cell-bound human gamma-G-immunoglobulin. PMID- 4163342 TI - Differences in the structure and variability of spray-like nerve endings in the joints of some mammals. PMID- 4163343 TI - Action of nitrous acid on recombination in E. coli. PMID- 4163344 TI - The effect of mercuric ions on growth and respiration of two coagulase-positive Staphylococcus aureus strains. PMID- 4163345 TI - Inhibition of Brucella-phage adsorption by Brucella endotoxins. PMID- 4163346 TI - Hemagglutinating properties of Miyagawanella strains. PMID- 4163347 TI - Studies on the relationships of somatic antigens among different groups of Rhizobium. PMID- 4163348 TI - The effect of ion exchange resins on CO2 production in anaerobic respiration of yeasts. PMID- 4163349 TI - The biosynthesis of vitamins of the B12 group in mixed cultures of bacteria. PMID- 4163350 TI - Semi-continuous corrinoid biosynthesis by Propionibacterium petersonii. PMID- 4163351 TI - The effect of herbicides on Rhizobium. I. Susceptibility of Rhizobium to herbicides. PMID- 4163352 TI - Recovery of infectious virus from brain tissue of rats treated with antirabic vaccine of Semple type. PMID- 4163353 TI - Serum uric acid values in various states of thyroid function. PMID- 4163354 TI - Autoradiography of exfoliated epithelial cells in the study of malignant bladder mucosa. A preliminary report. PMID- 4163355 TI - Myocardial ischaemia in infancy and childhood. AB - Examination of 135 consecutive necropsy specimens has shown that ischaemic myocardial injury is not uncommon in infancy and childhood. The extent of the myocardial change has been assessed by a technique of staining with acid fuchsin, first described by Selye (1958). The significance of the findings is discussed. PMID- 4163356 TI - Determination of serum thyroxine using a resin sponge technique. AB - A method is described for the determination of serum thyroxine using ion-exchange resin sponges. The principle is based on the use of protein-binding sites and part of the technique is similar to the Triomet resin uptake test. An isotope extraction recovery procedure is incorporated in the method. Studies of factors influencing the analysis are reported and the results of tests of accuracy, precision, and specificity are presented. Serum thyroxine iodine values are compared with protein-bound iodine estimations. The values found in health and disease are similar to the results of previous workers. The specificity of the analysis represents a considerable advantage over protein-bound iodine determinations since no interference is caused by iodides, iodine-containing contrast media, mercurial diuretics, mono-iodotyrosine, di-iodotyrosine, di iodothyronine, and also tri-iodothyronine in physiological amounts. Therapy with diphenylhydantoin and tri-iodothyronine will tend to depress protein-bound iodine levels and thyroxine values are similarly influenced. PMID- 4163357 TI - Antibodies involved in antigen-induced release of slow reacting substance of anaphylaxis (SRS-A) in the guinea pig and rat. AB - The antigen-induced release of SRS-A and histamine was studied in the guinea pig and rat using whole and fractionated antiserum preparations. Guinea pig 7Sgamma(1)-antibody sensitized sliced guinea pig lung tissue for antigen-induced release of both SRS-A and histamine; neither substance was released from lung tissue prepared with 7Sgamma(1)-antibody. Rats injected intraperitoneally with hyperimmune rabbit or rat antiserum released only SRS-A in significant amounts when challenged with antigen by the same route. A definite time interval between the injection of antiserum and challenge with antigen was required for optimal release of SRS-A. Fractionation of rat antiserum demonstrated that the immunoglobulin responsible for most of the SRS-A release from rat peritoneal tissue was a gammaG-antibody or fraction thereof. Acting in this capacity, the gammaG-antibody or its subfraction may be considered a second type of homocytotropic antibody. Fractions of rat antisera containing the first type of homocytotropic antibody, i.e. antibody mediating release of histamine and serotonin, prepared peritoneal tissues for the release of large amounts of these pharmacological agents and only small amounts of SRS-A. Two different mechanisms for the production of PCA lesions in the rat were considered. One of these involves the antigen-induced release of histamine and serotonin from mast cells sensitized by homocytotropic antibody. This reaction has an optimal latent period of 24-72 hr. The second mechanism involves the local combination of antigen with "hyperimmune" heterologous or homologous antisera. This reaction can be elicited after a latent period of 4 but not 24 hr; host complement and leukocyte lysosomal enzymes, as well as SRS-A, may be involved. PMID- 4163358 TI - Studies of the Vi (gamma-2c) subgroup of gamma-globulin. A relationship between concentration and genetic type among normal individuals. AB - Further delineation of the antigens characteristic of the Vi or gamma(2c) subgroup of gamma-globulin was carried out utilizing a number of rabbit and primate antisera. Two genetic antigens characteristic of this subgroup, Gm(b) and Gm(g), were also detected by precipitation techniques with certain of the antisera. These were clearly differentiated from antigens common to all proteins of this subgroup. The concentration, of Vi protein in normal and pathological sera from several population groups was measured quantitatively utilizing a variety of immunological procedures. All sera studied showed measurable levels. The mean value for Caucasian sera was 1.06 mg/ml, representing approximately 8% of gammaG-globulin. This agreed closely with a figure of 8.4% for the incidence of myeloma proteins of the Vi subgroup among all gammaG-myeloma proteins in Caucasians. A relationship was found between the Vi subgroup concentration and the specific genetic type of a given individual. Measurements of the Gm(b) genetic determinants, which are found solely in Vi-type proteins, brought forward this relationship. Gm(b+) individuals showed higher concentrations of Vi-type gamma-globulin than those who were Gm(b-), and this difference was statistically significant for both the homozygous and heterozygous states. It appeared that the structural genes for Gm(b+) polypeptide chains showed a greater synthetic capacity than those for Gm(b-) types. The possible significance of such effects in governing the relative composition of the antibody population in a given individual is discussed. PMID- 4163359 TI - Recovery of antibody activity from inactive hybrids of H and L chains. AB - Hybrid IgG molecules were prepared from the heavy and light chains of specifically purified antibody against two different haptens. One hybrid consisted of the H chains from the anti-p-azobenzoate antibody from one rabbit and L chains from the anti-p-azobenzenearsonate antibody from the second rabbit, and the second hybrid consisted of the opposite combination, light chains from the first rabbit and heavy chains from the second. The two hybrids were mixed at pH 8 and were found to be so stable in the mixture that even after 2 wk at 5 degrees C there was still only low hapten-binding activity toward p-iodobenzoate and p-iodobenzenearsonate. However, exposure of the mixture of hybrids to 1 M propionic acid followed by buffer at pH 8 resulted in recovery of binding activity for p-iodobenzoate and p-iodobenzenearsonate. Thus no exchange occurred between the light and heavy chains of the hybrids in the buffer, but exchange did occur on exposure to propionic acid, and this exchange favored a preferential combination among the chains in such a manner that effective antibody sites resulted. PMID- 4163360 TI - Gamma globulin and antibody formation in vitro. VII. Effect of x-irradiation on the secondary antibody response in vitro. AB - The present studies have shown that the influence of X-irradiation on the secondary antibody response in vitro is remarkably similar to its effect on the primary response in vivo. When sensitized tissue was first irradiated and then reexposed to antigen, the duration of the interval between irradiation and antigen addition determined the degree of inhibition of the secondary response obtained. A delay of 12 hr resulted in stronger inhibition than a delay of 6 hr, and an interval of 24 hr before reexposure to antigen caused complete suppression of antibody production to diphtheria toxoid and almost complete suppression when sheep RBC were used as the antigen. Induction of the secondary response in rabbit lymph node tissue in vitro followed by exposure to X-irradiation, revealed that immediate exposure to irradiation after antigen produced stronger inhibition of the subsequent response than irradiation on days 2-3. Irradiation on day 6 had no detectable effect. The effectiveness of the early radiation is probably due to prevention of the proliferation of the antibody-forming cells. BUDR was found to be effective at similar time periods as X-irradiation, whereas colchicine could still stop antibody formation when added late during the secondary response in vitro. It was noted that lymph nodes from some BSA-sensitized rabbits as late as 18 months after sensitization gave a response indistinguishable from a typical secondary response, even when not reexposed to antigen. PMID- 4163361 TI - Nuclear fluorescence employing antinucleoside immunoglobulins. AB - Fluoresceinated antinucleoside globulins were shown to react with the nuclei of L cells. The pattern of nuclear fluorescence was similar to the distribution of nuclear DNA. This reaction was shown to be specific by the following control experiments: 1. Absorption of the specific antibody from an antiadenosine globulin eliminated all fluorescence. 2. Treatment of the cells with nonfluorescent antiadenosine globulin, followed by staining with the fluorescent antiadenosine eliminated almost all of the fluorescence of the nucleus. 3. Treatment of the cells with DNase destroyed the ability of the nucleus to react with antiuridine fluorescent antibodies. 4. Fluoresceinated anti-BSA did not produce nuclear fluorescence. Nuclear fluorescence occurred only in cells harvested during the period of maximum DNA synthesis as measured by the uptake of thymidine. This correlates with the previously demonstrated specificity of the antibodies for denatured DNA. PMID- 4163362 TI - Studies on rabbit lymphocytes in vitro. VI. The induction of blast transformation with sheep antisera to rabbit IgA and IgM. AB - Sheep antisera specific for the three major immunoglobulin groups of the rabbit, i.e. IgG (gamma-chain), IgA (alpha-chain), and IgM (micro-chain), are each able to induce blast transformation of the peripheral lymphocytes of the rabbit when added to in vitro cultures. The per cent of lymphocytes transformed with each antiserum indicate that one-fourth of the peripheral lymphocytes carry or have the capacity to synthesize molecules of all three of the major immunoglobulin groups, and that the remaining three-fourths carry or have the capacity to synthesize only two (IgG and IgM). The data do not permit direct conclusions concerning the ability of a single cell to produce molecules belonging to more than one immunoglobulin group at the same time, or the ability of a given cell to make a transition from the synthesis of molecules of one immunoglobulin group to those of another group. PMID- 4163363 TI - Specificity of the antibodies produced by single cells following immunization with antigens bearing two types of antigenic determinants. AB - A combination of double immunofluorescent technique and radioautographic localization of radioactive antigens was used to investigate the question whether single antibody-producing cells can make antibodies of more than one specificity after immunization with antigens bearing more than one determinant. When guinea pig gamma(2)-globulins, containing the F(ab')(2) and Fc determinants, were used to immunize rabbits, a small percentage of cells (3.7%) were stained with both the anti-F(ab')(2) and anti-Fc reagents. These results were shown to be due to the lack of absolute specificity of the detecting antigen and antibody reagents which can be obtained for use in this system. However, when immunological systems such as hapten-protein conjugates were used, and where completely specific antigen and antibody reagents could be prepared, the results were unequivocal. The individual lymph node cells from rabbits or guinea pigs immunized with hapten protein conjugates produced antibodies against the hapten or antibodies against the antigenic determinants of the carrier molecule, never antibodies against both specificities. PMID- 4163364 TI - The roentgen diagnosis of Whipple's disease (intestinal lipodystrophy), with emphasis on improvement following antibiotic therapy. PMID- 4163365 TI - Metastatic carcinoma to the mesentery and gut. PMID- 4163366 TI - Forms of insulin-like activity at different sites of the circulation in dogs. PMID- 4163367 TI - Alterations in the antigenic constitution of renal glomerular capillaries accompanying the histological maturation of renal glomeruli in the rat. PMID- 4163368 TI - Antinuclear factor in rheumatoid arthritis and related diseases. PMID- 4163369 TI - Separating fact from fiction in auto smog control. PMID- 4163370 TI - Airborne carcinogens and allied compounds. PMID- 4163371 TI - Minimizing pollution from car exhaust gases. PMID- 4163373 TI - The vascular system in the rat upper incisor and its development. PMID- 4163372 TI - Fluctuation of the anterior hypophyseal cell numbers of the female rat. PMID- 4163374 TI - Identity of trypanosome growth factors in serum. II. Active globulin components. PMID- 4163375 TI - Autoimmune reactions in rats with Plasmodium berghei infection. PMID- 4163376 TI - Electron microscope observations on the cuticle and submicroscopic binding of antibody in Ascaris suum larvae. PMID- 4163377 TI - Prevention of Rh isoimmunization. Progress report of the clinical trial in mothers. PMID- 4163378 TI - Tetracycline and thyroid function. PMID- 4163379 TI - Panniculitis, vasculitis, and a positive lupus erythematosus cell test. PMID- 4163380 TI - Radiation-induced thyroid dysfunction in the dog. PMID- 4163381 TI - [Changes in the function of the ciliated epithelium of the nasal mucosa under the influence of hexachlorane]. PMID- 4163382 TI - [On the immunochemical structure of antitoxic horse beta-2A-globulin]. PMID- 4163383 TI - Posttransfusion hepatitis and its possible prophylaxis with gamma globulin. PMID- 4163384 TI - Cadaveric transplants. PMID- 4163385 TI - The measurement and significance of the urinary flow rate. PMID- 4163386 TI - [Rapid identification of sanguicolous parasites by staining with acridine orange and fluorescence microscopy]. PMID- 4163387 TI - [Observation of the localization of gamma-1A-globulin in the skin and mucosa in relation to allergic reactions]. PMID- 4163388 TI - Acriflavine-induced immunological paralysis: the effect of varying antigen doses. PMID- 4163389 TI - A.S.D.C. offers new slide/lecture in color for young children. PMID- 4163390 TI - Dental office audio-visual patient education. PMID- 4163391 TI - The fate of macroaggregated albumin used in lung scanning. PMID- 4163393 TI - Techniques used in the construction of cold cure acrylic skulls and sections of skulls. PMID- 4163392 TI - [Collagen biosynthesis in gingival tissues of guinea pig]. PMID- 4163394 TI - [The dynamics of protein-bound iodine of the blood plasma in different diseases of the thyroid gland]. PMID- 4163395 TI - [Fundamentals and clinical value of thyroid function exploration]. PMID- 4163396 TI - [Study of the biological activity of globulin isolated from a perfusate of tissues of irradiated and non-irradiated dogs (experiments on rabbits)]. PMID- 4163397 TI - [Study of kidney function in patients with adenoma of the prostate by means of radioisotope renography]. PMID- 4163398 TI - [The determination of residual urine by the radioisotope method]. PMID- 4163399 TI - Inhibition of RNA synthesis in HeLa and L cells by Mengovirus. PMID- 4163400 TI - Immunological evidence for the appearance of a new DNA-polymerase in cells infected with vaccinia virus. PMID- 4163401 TI - Thyroid hormone metabolism in the pregnant syrian hamster (Mesocricetus auratus). PMID- 4163402 TI - Abnormal regulation of thyroid function in patients with chronic Chaga's disease. PMID- 4163403 TI - Perfusion-fixation of the brain with chrome-osmium solutions for the rapid Golgi method. PMID- 4163404 TI - [Studies of immuno-allergic impairment of testicles in the guinea pig]. PMID- 4163405 TI - Genetics of juvenile diabetes mellitus. PMID- 4163406 TI - Results of treatment of breast cancer at Aberdeen Royal Infirmary 1940-55. PMID- 4163407 TI - Further observations on renal transplants in man from cadaveric donors. PMID- 4163408 TI - A study on the ground substance of arteries, veins and grafted veins in dogs. PMID- 4163409 TI - Electron microscopic study of the rodent "picodnavirus" X14. PMID- 4163410 TI - [Issues of industrial hygiene in the production of enriched hexachlorocyclohexane]. PMID- 4163411 TI - Interaction of Vi antigen with proteins. AB - Whiteside, Roberta E. (Boston University School of Medicine, Boston, Mass.), and Edgar E. Baker. Interaction of Vi antigen with proteins. J. Bacteriol. 92:1597 1603. 1966.-Purified Vi antigen (Vi) mixed in equal amounts with bovine serum albumin (BSA) or human gamma globulin (HGG) at pH values above 4.7 formed a complex which was not precipitated by trichloroacetic acid or tungstic acid. At pH values below 4.7, the interaction between Vi and either BSA or HGG produced insoluble complexes except when excess Vi antigen was present. When sufficient Vi was present at the lower pH values, the soluble complex was not precipitated by trichloroacetic acid. Other acid polysaccharides tested did not form trichloroacetic acid-soluble complexes with BSA. When subjected to immunoelectrophoresis, the Vi-BSA complex migrated in agar at a rate different from that of either BSA or Vi alone. The complex reacted with both Vi and BSA antiserum. The addition of either BSA or Vi antiserum to a Vi-BSA complex resulted in dissociation of the complex and precipitation of either Vi or BSA, depending upon the antiserum used. Vi antigen mixed with purified O antigen from Salmonella typhosa formed a complex which migrated in agar at a rate different from that of either component alone when subjected to immunoelectrophoresis. PMID- 4163413 TI - The jejunum after kwashiorkor. PMID- 4163412 TI - Persistent infection of cells in culture by measles virus. I. Development and characteristics of HeLa sublines persistently infected with complete virus. AB - Rustigian, Robert (Tufts University School of Medicine, Boston, Mass.). Persistent infection of cells in culture by measles virus. I. Development and characteristics of HeLa sublines persistently infected with complete virus. J. Bacteriol. 92:1792-1804. 1966.-After the development of marked cytopathic effects in HeLa cultures infected with the Edmonston strain of measles virus, renewed cell growth occurred, and HeLa sublines persistently infected with measles virus were obtained. Persistent infection has occurred in a large fraction of the cells of infected clonal lines for more than 300 to 500 cell generations during a period of 6 years. One mechanism by means of which infection was maintained in the clonal lines is transmission of virus or viral subunits from cell to cell at division. Continued subculture of the persistently infected populations resulted in the virtual disappearance of cytopathic effects, a marked decrease in the amount of extracellular virus, and alterations in the cytopathogenicity of virus recovered from persistently infected populations. The intracellular virus-host cell events in late passages of the infected clonal lines appeared to be similar to those in cells of primary infected cultures at early stages of infection, as judged by the pattern of viral immunofluorescence and the very low incidence of cells with intranuclear inclusion bodies. Cultures of the persistently infected clonal lines were highly resistant to super infection by parent Edmonston virus. Cultures of one of these clonal lines were just as susceptible as normal HeLa cultures to vaccinia, herpes simplex, and polio type 2 viruses, and a simian agent, with a possible low degree of resistance to the simian agent. PMID- 4163414 TI - The fluid mechanics of the control of reflux. PMID- 4163415 TI - The cardia in swallowing, eructation, and vomiting. PMID- 4163416 TI - Encephalopathy and fatty degeneration of the viscera. Acid-base observations. PMID- 4163417 TI - Acute pyelonephritis. Incidence of reinfection in 100 patients. PMID- 4163418 TI - Jaundice and oral contraceptive drugs. PMID- 4163419 TI - Small-bowel changes in dermatitis herpetiformis. PMID- 4163420 TI - Inheritance of alcoholism. Its association with colour-blindness. PMID- 4163421 TI - Chronic pyelonephritis or glomerulonephritis? PMID- 4163422 TI - Treatment of the fetus with Rhesus disease. PMID- 4163423 TI - The control of venereal disease. PMID- 4163424 TI - Corneal lymphatics and grafts. PMID- 4163425 TI - Xga. PMID- 4163426 TI - The pre-discharge ward. PMID- 4163427 TI - Infectious drug resistance in Escherichia coli isolated from healthy farm animals. PMID- 4163428 TI - Public baths revisited. PMID- 4163429 TI - Training the specialist surgeon. PMID- 4163430 TI - Psyche submerged. PMID- 4163431 TI - Management of the patient with inoperable bronchogenic carcinoma. PMID- 4163432 TI - [Experiences in automation and mechanization of the process of gamma-globulin production]. PMID- 4163434 TI - Passively-acquired immunity in experimental cryptococcosis. PMID- 4163433 TI - Immune studies in candidiasis. 3. Precipitating antibodies in systemic candidiasis. PMID- 4163435 TI - Synthesis of donor type gamma-G-globulin following thymus transplantation in hypo gamma-globulinaemia with severe lymphocytopenia. PMID- 4163436 TI - Karyometric investigations of the erythroblastic system. Normal values. PMID- 4163437 TI - Differential Mantoux testing in the diagnosis of atypical mycobacterial infection in children. PMID- 4163438 TI - Effect of thyrocalcitonin on bone. PMID- 4163439 TI - Reduction of gastric iron-binding protein in haemochromatosis. A previously unrecognised metabolic defect. PMID- 4163440 TI - Resistance of insulin to insulinase. A genetic discriminant in diabetes mellitus. PMID- 4163441 TI - Propranolol in acute myocardial infarction. A multicentre trial. PMID- 4163442 TI - Potassium, glucose, and insulin in treatment of heart block after myocardial infarction. PMID- 4163443 TI - Changes in pulmonary function 6-12 months after recovery from myocardial infarction. PMID- 4163444 TI - Prolapse of the umbilical cord. PMID- 4163445 TI - Correction of pulmonary atresia with a homograft aortic valve. PMID- 4163447 TI - Renal disease and rheumatoid arthritis. PMID- 4163446 TI - The long-term prognosis of generalized miliary tuberculosis in children. PMID- 4163449 TI - Uterine cancer. PMID- 4163448 TI - Isoniazid: how much a carcinogen? PMID- 4163451 TI - Carcinoma of the nasopharynx. PMID- 4163450 TI - Calcifications in human cartilage. PMID- 4163452 TI - Stones in a hot climate. PMID- 4163453 TI - Medical staffing in the National Health Service in England and Wales. PMID- 4163455 TI - Old people and their relatives. PMID- 4163454 TI - Mast cells and cancer in the skin of mice. PMID- 4163456 TI - Functions of medical boards. PMID- 4163457 TI - Thomas Arthur Munro. PMID- 4163458 TI - [Apropos of hyperimmune globulins in the treatment of whooping-cough]. PMID- 4163459 TI - [Educational aids PMP and MEDSB]. PMID- 4163460 TI - [On the ultrastructure of foliate villi of the Indian rhinoceros placenta (Rhinoceros unicornis L.)]. PMID- 4163461 TI - [Importance of defense mechanisms in therapeutic treatment of some dermatoses. (Justification of this clinical note)]. PMID- 4163462 TI - Glutaraldehyde fixation of routine surgical eye tissue. PMID- 4163463 TI - [Drug treatment of prostatic hypertrophy]. PMID- 4163464 TI - [On the fungicidal properties of components of commercial benzene hexachloride]. PMID- 4163465 TI - Biochemical findings in long-term oral contraceptive usage. I. Liver function studies. PMID- 4163467 TI - Continuous progestogen contraception: a dose relationship study with chlormadinone acetate. PMID- 4163466 TI - Endometrial enzyme histochemistry in oral contraceptive therapy. PMID- 4163468 TI - Studies on the inhibition of actinomycin biosynthesis by D-valine. PMID- 4163469 TI - Cloning of immunoglobulin-producing human leukemic and lymphoma cells in long term cultures. PMID- 4163470 TI - Evidence for anti-Gm(a) antibody in gamma A immunoglobulins. PMID- 4163471 TI - Mechanism of action of TSH studied by organ culture of fetal rat thyroid gland. PMID- 4163473 TI - Fluorescent antibody studies with Nocardia asteroides. I. Preliminary attempts in removing cross-reacting factors. PMID- 4163472 TI - [Endemic goiter in the Provincia de Misiones (Argentina)]. PMID- 4163474 TI - The amount of gammaglobulin on the surface of leukocytes taken from diabetics and normal subjects. PMID- 4163475 TI - Isolation of antibodies by gel-filtration. PMID- 4163476 TI - Allergic type skin reactions in animals with alloxan diabetes. PMID- 4163477 TI - [The mechanism underlying the influence of the vagus nerve on ventricular extrasystole]. PMID- 4163478 TI - The orienting reflex during waking and sleeping. PMID- 4163479 TI - Discriminating among states of consciousness by EEG measurements. A study of four subjects. PMID- 4163480 TI - The effect of variations in total sleep time on the occurrence of rapid eye movement sleep in cats. PMID- 4163481 TI - Physiological correlates of steady potential shifts during sleep and wakefulness. I. Sensitivity of the steady potential to alterations in carbon dioxide. PMID- 4163482 TI - Physiological correlates of steady potential shifts during sleep and wakefulness. II. Brain temperature, blood pressure, and potential changes across the ependyma. PMID- 4163483 TI - Neurophysiological evidence for a differential organization of the mesencephalic reticular formation. PMID- 4163484 TI - Modification of sensory cortical evoked potentials by hippocampal stimulation. PMID- 4163485 TI - Amplitude measurement of the sleep electroencephalogram. PMID- 4163486 TI - Depth EEG studies in a patient with fourteen and six per second positive spikes. PMID- 4163487 TI - A simple cable for reduction of movement artifact in electroencephalographic recordings. PMID- 4163488 TI - Failure of long-acting thyroid stimulator globulin (LATS) and serum to stimulate thyroid function in the chick. PMID- 4163490 TI - [On the use of the vital staining method in determining the standards of air pollution]. PMID- 4163491 TI - The acridine orange and dye exclusion viability tests applied to irradiated Ehrlich tumour cells. PMID- 4163489 TI - The fine structure of the cuneate nucleus in normal cats and following interruption of afferent fibres. An electron microscopical study with particular reference to findings made in glees and nauta sections. PMID- 4163492 TI - Frequency of secondary amyloidosis in hospital patients in Malawi. PMID- 4163493 TI - Histology of rat molar pulp at different ages. PMID- 4163494 TI - Effects of age on dentin demonstrated with azure A. PMID- 4163495 TI - Bacterial and viral coproantibodies in breast-fed infants. PMID- 4163496 TI - Sarcoplasmic reticulum of striated muscle: localization of potential calcium binding sites. AB - Fish branchial muscle stained at a low pH with thorium dioxide shows localization of the stain over the sacroplasmic reticulum. Binding of the positively charged thorium micelles with dissociated acid groups of polyanions in this region suggests a possible mechanism for the storage and release of divalent cations such as calcium. PMID- 4163497 TI - Ontogenesis of the rat corticospinal tract. Normal events and effects of intra uterine neurosurgical lesions. PMID- 4163498 TI - Precapillary arteriovenous anastomoses. "Thoroughfare channels" in the brain. PMID- 4163499 TI - Immunofluorescent localization of the third and the fourth component of complement in synovial tissue from patients with rheumatoid arthritis. PMID- 4163500 TI - Electroimmunodiffusion (EID): a simple, rapid method for quantitation of immunoglobulins in dilute biological fluids. PMID- 4163501 TI - Intralaminar distributions of proteolipid protein and residue protein in human frontal cortex. PMID- 4163502 TI - Tubal metaplasia of the endometrium. PMID- 4163503 TI - Wiskott-Aldrich syndrome: clinical, immunologic, and pathologic observations. PMID- 4163504 TI - Sixth National Burn Seminar. Control of sepsis in burns. PMID- 4163505 TI - Sixth National Burn Seminar. The anabolic aspect of plasma protein metabolism in burn patients. PMID- 4163506 TI - Pentagastrin as a stimulant of maximal gastric acid response in man. A multicentre pilot study. PMID- 4163507 TI - Failure of high dialysis-fluid glucose to prevent the disequilibrium syndrome. PMID- 4163508 TI - Finger-print pattern and the sex chromosomes. PMID- 4163509 TI - Response to a gluten-free diet of patients with the coeliac syndrome. PMID- 4163510 TI - Paneth-cell deficiency. PMID- 4163511 TI - The risk of recurrence after two children with central-nervous-system malformations. PMID- 4163512 TI - Successful repeated platelet-transfusion in radiation-induced bone-marrow failure. PMID- 4163513 TI - Haemodynamic consequences of atrial septostomy without thoracotomy in an infant with transposition of the great arteries. PMID- 4163514 TI - Carcinoma of the nasal cavity and accessory sinuses in woodworkers. PMID- 4163515 TI - Antinuclear factors in synovial fluids. PMID- 4163516 TI - Paneth-cell function. PMID- 4163517 TI - Biochemistry of depression. PMID- 4163518 TI - Paneth cells and coeliac disease. PMID- 4163519 TI - Administration of teaching hospitals. PMID- 4163520 TI - The abortion bill. PMID- 4163521 TI - Definition of suicide. PMID- 4163522 TI - The boundaries between physiology, pathology, and irreversibility after injury. PMID- 4163523 TI - Immunohistological and serological studies in endomyocardial fibrosis. PMID- 4163524 TI - Effects of sustained maternal hypertension on foetal growth and survival. PMID- 4163525 TI - Haemodynamic factors in the development of acute pulmonary oedema in renal failure. PMID- 4163526 TI - Effects of hyberbaric oxygen on shallow, stationary broth cultures of Escherichia coli. PMID- 4163527 TI - A simple method for producing antibody specific to a single selected diffusible antigen. PMID- 4163528 TI - Muscle antibodies in myasthenic mothers and their babies. PMID- 4163529 TI - Effect of glucagon on insulin release in vitro. PMID- 4163530 TI - Chromosomal abnormalities in human diploid cells infected with mycoplasma and their possible relevance to the aetiology of Down's syndrome (mongolism). PMID- 4163531 TI - Standing-room only? PMID- 4163532 TI - Blood-groups and the intestine. PMID- 4163533 TI - Academic deep freeze. PMID- 4163534 TI - Industrial carcinogens: new legislation needed. PMID- 4163535 TI - The multiplication of man or Noah's new flood. PMID- 4163536 TI - The case against the promotion of health. PMID- 4163537 TI - Brain damage after dental anesthesia. PMID- 4163539 TI - Guy Pascoe Crowden. PMID- 4163538 TI - Chronic ethchlorvynol intoxication. PMID- 4163540 TI - Charles Edward Kindersley. PMID- 4163541 TI - A controlled trial of antiserum in the treatment of tetanus. PMID- 4163542 TI - The relation between glucose tolerance and atherosclerotic vascular disease. PMID- 4163543 TI - Effect of short-term sucrose restriction on serum-lipid levels. PMID- 4163544 TI - Reduction of haematocrit and red-blood-cell volume in patients with polycythaemia secondary to hypoxic lung disease by dapsone and pyrimethamine. PMID- 4163545 TI - Effects of propranolol on the hormonal and metabolic responses to insulin-induced hypoglycaemia. PMID- 4163546 TI - Hypoglycaemia precipitated by propranolol. PMID- 4163547 TI - Antiperistaltic segments after massive intestinal resections. PMID- 4163548 TI - Blood-gas tensions during apnoea in hyperbaric oxygen. PMID- 4163549 TI - Precipitins against extracts of thatched roofs in the sera of New Guinea natives with chronic lung disease. PMID- 4163550 TI - Evolution of sex chromosomes in mammals and birds. PMID- 4163551 TI - Training our specialists. PMID- 4163552 TI - The world's deformities. PMID- 4163553 TI - Fire and hyperbaric oxygen. PMID- 4163554 TI - Ignition by electrostatic sparks in hyperbaric oxygen. PMID- 4163555 TI - Setting up a therapeutic community. PMID- 4163556 TI - Liberation of patients. PMID- 4163557 TI - Reaction after dichloralphenazone. PMID- 4163558 TI - A gamma-globulin genetic factor related to Gm(a) but localized to a different portion of the same heavy chains. PMID- 4163559 TI - Rapid method for demonstrating intracellular pleuropneumonia-like organisms in a strain of hamster kidney cells (BHK 21 C13). PMID- 4163560 TI - Peripheral neuropathy with bronchiectasis. PMID- 4163561 TI - Development of the tracheal glands in man. Number, density, structure, shape, and distribution of mucous glands elucidated by quantitative studies of whole mounts. PMID- 4163562 TI - [The role of the synthesis of nucleic acids in the mechanism of stabilization of conditioned reflexes and memory]. PMID- 4163563 TI - Developmental and acquired variations in erythrocyte carbonic anhydrase isozymes. PMID- 4163564 TI - Studies in vascular permeability of human skin bradykinin. PMID- 4163565 TI - Role of mast cells in the inflammatory defense mechanism in the skin of rats. PMID- 4163566 TI - [Monocytic leukemia with gamma-G-paraproteinemia after roentgen irradiation and cytostatic therapy of a myosarcoma]. PMID- 4163567 TI - Receptive fields in the accessory optic system of the rabbit. PMID- 4163568 TI - The regenerative capacity of the telencephalon of the goldfish and rat. PMID- 4163569 TI - Influence of stimulation of the septal area on visual evoked potentials. PMID- 4163570 TI - A study of the distribution of epidermal dendritic cells in pigmented and unpigmented skin. PMID- 4163571 TI - Surgical wound sepsis in a general hospital. PMID- 4163572 TI - The bursa of Fabricius and the immune response. 2. An electrophoretic analysis of the spleen extracts of bursectomized animals. PMID- 4163573 TI - Reaction of antinuclear factors with polymorphonuclear leucocytes. 1. Absorption studies. PMID- 4163574 TI - The value of radiotherapy in the treatment of carcinoma of the colon. PMID- 4163575 TI - Studies on the purification of the human serum group specific component. PMID- 4163576 TI - Stainability of decalcified human coronal dentine. PMID- 4163577 TI - Relationship between microradiography and stainability of human coronal dentine. PMID- 4163578 TI - Staining mast cells in human gingiva. PMID- 4163579 TI - Vital staining and electron microscopy of the intramuscular nerve endings in the neuropathy of adult coeliac disease. PMID- 4163580 TI - Neurological disorders associated with adult coeliac disease. PMID- 4163581 TI - Mental deficiency associated with muscular dystrophy. A neuropathological study. PMID- 4163582 TI - Histone differentiation and nuclear activity. PMID- 4163583 TI - [Association of IgM with albumin in certain cases of Waldenstrom's disease]. PMID- 4163584 TI - Electrophoretic heterogeneity of alpha-2-macroglobulin. PMID- 4163585 TI - IgM light chain types in suspected macroglobulinaemia. PMID- 4163586 TI - Resistance of differentiating neurons to the antimetabolite, amethopterin. PMID- 4163587 TI - Effects of subthalamic lesions on sensory-evoked potentials in the reticular formation and sensorimotor cortex. PMID- 4163588 TI - Calcium localized in odontogenic cells of rat mandibular teeth by the glyoxal bis (2-hydroxyanil) method. PMID- 4163589 TI - Mast cells in gingival tissue. I. A standardized method for fixation and staining of the mast cell in human gingival tissue. PMID- 4163590 TI - Free thyroxine levels in children with mongolism. PMID- 4163591 TI - Some observations of renal function after prostatectomy. PMID- 4163592 TI - Studies on the hemolytic titer of the complement and on the intensity of precipitation in the beta-1C globulins in the course of certain diseases. PMID- 4163593 TI - Autologous immune-complex pathogenesis of experimental allergic glomerulonephritis. AB - A renal tubular epithelial antigen is deposited in association with gamma globulin and complement in glomeruli from rats with experimental allergic glomerulonephritis induced by immunization with renal tubular antigens. Apparently, in normal kidneys this antigen is concentrated in the distal segment of the proximal convoluted tubular epithelium, and the principal source of this antigen in the glomerular deposits is autologous. This form of glomerulonephritis provides an experimental prototype for what may be termed "autologous immunecomplex" diseases. PMID- 4163594 TI - Hereditary disorders of the retina and choroid. PMID- 4163595 TI - [On the palliative treatment of inoperable esophageal carcinoma]. PMID- 4163596 TI - A generalized disorder of nervous system, skeletal muscle and heart resembling Refsum's disease and Hurler's syndrome. I. Clinical, pathologic and biochemical characteristics. PMID- 4163597 TI - A generalized disorder of nervous system, skeletal muscle and heart resembling Refsum's disease and Hurler's syndrome. II. Ultrastructure. PMID- 4163598 TI - Influence of pargyline on the toxicity of morphine and pethidine in mice. PMID- 4163599 TI - Investigation with tritiated thymidine of the relationship between the sex chromosomes, sex chromatin, and the drumstick in the cells of the female nine banded armadillo, Dasypus novemcinctus. PMID- 4163600 TI - Tinea Nigra. Report of five cases seen in Venezuela. PMID- 4163601 TI - Actinic elastosis and pseudoxanthoma elasticum. PMID- 4163602 TI - The in vitro activity of the microsomal fraction isolated from the spleen and the lymph nodes after immunization of the donor. PMID- 4163603 TI - Allotypic specificities in pigs. II. Types of frequency of allotypic specificities of gamma M globulin in pigs. PMID- 4163604 TI - Studies of the proteins of secretions from two villous tumours of the rectum. PMID- 4163605 TI - [Studies on the functional relationship between liver parenchyma and mesenchyma. Indocyanine green clearance under the influence of antigen]. PMID- 4163606 TI - Histochemical properties of insular beta-cells after short tryptic digestion. PMID- 4163607 TI - Histochemical demonstration of the activity of phosphatases by means of leadrhodizonate. PMID- 4163608 TI - [On the demonstrability of neurosecretory substance with chromalum-gallocyanine in the dog supra-optico-hypophyseal system]. PMID- 4163609 TI - Serum free thyroxine and thyroxine-binding protein studies in patients with supraventricular tachycardias. PMID- 4163610 TI - Occurrence in thyrotoxicosis of a gamma globulin which protects LATS from neutralization by an extract of thyroid gland. PMID- 4163611 TI - Studies of 47Ca metabolism in acromegaly. PMID- 4163612 TI - Congenital goiter with hypothyroidism and iodo-serum albumin replacing thyroglobulin. PMID- 4163613 TI - Sex-related differences in the binding in serum of thyroid hormones. PMID- 4163614 TI - Regulation of the pituitary-thyroid axis in man: relationship of TSH concentration to concentration of free and total thyroxine in plasma. PMID- 4163615 TI - Goitrous hypothyroidism induced by amino-glutethimide, anticonvulsant drug. PMID- 4163616 TI - Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone. PMID- 4163617 TI - Synthesis and pharmacology of 6-methylenedihydrodesoxymorphine. PMID- 4163618 TI - The contribution of the precentral gyrus to the pyramidal tract of man. PMID- 4163619 TI - Ribonucleic acid in canine mast cell granules and the possible interrelationship of mast cells and plasma cells. PMID- 4163620 TI - Live attenuated mumps virus vaccine. 1. Vaccine development. PMID- 4163621 TI - Immunoglobulin responses to experimental human infection with adenovirus types 26 and 27. PMID- 4163622 TI - Comparison of several methods for isolation of rat peritoneal mast cells. PMID- 4163623 TI - Molecular weight of human renin. PMID- 4163624 TI - Persistent polioviral infection of the intact amniotic membrane. II. Existence of a mechanical barrier to viral infection. PMID- 4163625 TI - Structure and heterogeneity of antibodies. PMID- 4163626 TI - The involvement of a globulin fraction from serum and lymphoid cells in the passive transfer of contact allergy. PMID- 4163627 TI - Passive transfer of a delayed skin reactivity to 2,4-dinitrochlorobenzene (DNCB) with the immunoglobulin A (IgA) fraction of serum and lymphoid cells. PMID- 4163628 TI - Lattice corneal dystrophy. An inherited variety of amyloidosis restricted to the cornea. PMID- 4163629 TI - Carcinoma of the male breast. PMID- 4163630 TI - [Histological and histochemical study of the dog liver after orthotopic transplantation]. PMID- 4163631 TI - [Histamine liberation by rat mastocytes in presence of hexadimethrine bromide]. PMID- 4163632 TI - [Cytological and cytochemical study of the effects of hexadimethrine bromide on rat peritoneal mast cells]. PMID- 4163633 TI - A rapid semimicro method for determining protein-bound iodine. PMID- 4163634 TI - [Successive cytophotometric determination of deoxyribonucleic acid, histone and total protein]. PMID- 4163635 TI - Light and heavy chain components of gamma globulins in urines of normal persons and patients with agammaglobulinemia. AB - A heavy chain component of gammaG-globulins in normal urines has the characteristics of the proteolytic digestion product, Fc-fragment. This fragment is estimated to compose up to 15% of the gamma globulins present in urines. In contrast to urinary light chains, the urinary Fc-like fragment probably represents a catabolic component in normal gammaG-globulin metabolism. The light chains of the urine constitute more than half the total gamma globulin present. The calculated kappa/lambda ratio of light chains averaged 1.9 in ten urines, but the ratio in individual urines varied widely to either side of this figure. In two adult patients with agammaglobulinemia whose sera contained less than one hundredth the normal gamma globulin levels, the urinary Fc-like fragment was absent, whereas the light chain levels were only one-tenth the average normal level. Treatment with exogenous gamma globulins resulted in normal or near normal Fc-like fragment excretion, whereas light chain excretion was only modestly affected. PMID- 4163636 TI - Rabbit gamma A- and gamma M-immunoglobulins with allotypic specificities controlled by the a locus. PMID- 4163637 TI - Some observations on the ABO antigen sites of the erythrocyte membranes of adults and newborn infants. PMID- 4163638 TI - Streptococcal related glomerulonephritis. II. Glomerulonephritis in rhesus monkeys immunologically induced both actively and passively with a soluble fraction from human glomeruli. PMID- 4163639 TI - Characterization of human serum and nasal hemagglutinating antibody to Francisella tularensis. PMID- 4163640 TI - Demonstration of tissue-specific soluble antigens in human skin by immunodiffusion. PMID- 4163641 TI - Bacteriophage neutralizing activity of fragments derived from rabbit immunoglobulin by papain digestion. PMID- 4163642 TI - Possible effects of various ototoxic drugs upon the ATP-hydrolyzing system in the stria vascularis and spiral ligament of the guinea pig. PMID- 4163643 TI - Autonomous functioning nodules and thyrotoxicosis. PMID- 4163644 TI - The neuropathy of sulfatide lipidosis (metachromatic leukodystrophy). PMID- 4163645 TI - Immunosuppressive drugs in the management of malignant and severe rheumatoid arthritis. PMID- 4163646 TI - The hereditary tapetoretinal degenerations. PMID- 4163647 TI - Penicillin hypersensitivity with eosinophilia; a case report with immunologic studies. PMID- 4163648 TI - Hypothalamic vasopressor and vesicopressor pathways. I. Functional studies. PMID- 4163649 TI - Hypothalamic vasopressor and vesicopressor pathways. II. Anatomic study of their course and connections. PMID- 4163650 TI - ATPase activity in discharging cortical lesions induced by freezing. PMID- 4163651 TI - Fine structure of partially demineralized enamel. PMID- 4163652 TI - Histological recognition of gingival reticulin. PMID- 4163653 TI - Protein adsorption on bovine enamel. PMID- 4163655 TI - An electron microscopic study of the acquired pellicle and plaque formed on the enamel of human incisors. PMID- 4163654 TI - Aldehyde fuchsin-Halmi reaction in fibres of the human dental pulp. PMID- 4163656 TI - [Contribution to the knowledge of the species Lyophyllum karsten and calocybe Kuhner (Agaricales, Basidiomycetes). I. The fine structure of the carminophil granulation]. PMID- 4163657 TI - Heparin inhibition of histamine release and its relation to calcium. PMID- 4163658 TI - Uptake and release of 3-H-histamine in cat submaxillary gland. PMID- 4163660 TI - Comparative fine structure of the trigeminal ganglia, including human autopsy studies. PMID- 4163659 TI - Evidence for temporal and quantitative control of genetic transcription and translation during slime mold development. PMID- 4163661 TI - Fine structure of the normal trigeminal ganglion in the cat and monkey. PMID- 4163662 TI - Correlated light and electron microscopic observations on the normal trigeminal ganglion and sensory root in man. PMID- 4163663 TI - Electron microscopy of the gasserian ganglion in trigeminal neuralgia. PMID- 4163664 TI - Pathology of trigeminal neuralgia: light and electron microscopic observations. PMID- 4163665 TI - Thymic alymphoplasia, lymphoma, and dys-gamma-globulinemia, hyper-gamma A-, normo gamma M-, hypo-gamma G, a-gamma D-, and gamma E-globulinemia, plasmacytosis, normal delayed hypersensitivity, severe allergic reactions, and Coombs' positive anemia. PMID- 4163666 TI - [New patent medicines. 12. The ovulation inhibitor ovosistone and the progestational hormone chlormadinone]. PMID- 4163667 TI - Liberation of histamine in man. Gas chromatography of ring methylated imidazoleacetic acids in urine. PMID- 4163668 TI - Alpha-oxidation of branched chain fatty acids in man and its failure in patients with Refsum's disease showing phytanic acid accumulation. PMID- 4163669 TI - Rodent plasmodia of the Republique Centrafricaine: the sporogony and tissue stages of Plasmodium chabaudi and P. berghei yoelii. PMID- 4163670 TI - The insulin-like activity in serum determined by the rat epididymal fat method. VI. Insulin-like activity in serum and serum-protein fractions from normal persons and patients with diabetes mellitus. PMID- 4163672 TI - Fractionation of mouse serum proteins. An evaluation of two methods with special reference to the gamma-globulins. PMID- 4163671 TI - Localization of plasma proteins in small dermal blood vessels in diabetes. Preliminary report. PMID- 4163673 TI - Comparison of Mycobacterium paratuberculosis and other mycobacteria, using standard cytochemical tests. PMID- 4163674 TI - Selective staining of chromatin in hematogenous lymphocytes in nodes. PMID- 4163675 TI - Visceral involvement in lipoid proteinosis. PMID- 4163676 TI - Three-dimensional visualization of elastic fibers in thick skin sections. PMID- 4163677 TI - The formation and properties of organic films on teeth. PMID- 4163678 TI - Odontogenic myxoma: some histochemical considerations. PMID- 4163679 TI - The ultrastructure of negatively stained platelets. Some physiologic implications. PMID- 4163680 TI - Electrographic correlates of behavior in the frog with special reference to sleep. PMID- 4163681 TI - Sleep induction by progesterone in the pre-optic area in cats. PMID- 4163682 TI - EEG studies during acidaemia and alkalaemia in children undergoing cardiac surgery. PMID- 4163683 TI - EEG responses to light flashes during the observation of stabilized and normal retinal images. PMID- 4163684 TI - Changes in visual recovery functions and unit activity produced by frontal and temporal cortex stimulation. PMID- 4163685 TI - Effects of stimulation of the superior colliculus and lateral thalamus on visual evoked potentials. PMID- 4163686 TI - The relationship between neuron activity and cortical steady potentials. PMID- 4163687 TI - Duration and frequency patterns of the after-discharge from septum and amygdala. PMID- 4163688 TI - Mental arithmetic and eye opening. An EEG frequency analysis and GSR study. PMID- 4163689 TI - Discriminator and integrator instrument for an on line frequency analysis of single unit discharges. PMID- 4163690 TI - A chronically fixed stereotaxic device for intracerebral exploration with macro- and micro-electrodes. PMID- 4163691 TI - A platinum micro-electrode for intracerebral exploration with a chronically fixed stereotaxic device. PMID- 4163692 TI - Testing metal micro-electrodes. PMID- 4163694 TI - Periventricular Gomori-positive glia in the hypothalamus of the rabbit. PMID- 4163693 TI - Somatotopical organization of the projection from the nucleus interpositus anterior of the cerebellum to the red nucleus. An experimental study in the cat with silver impregnation methods. PMID- 4163695 TI - [Studies on eosinophilia of hyalin cartilage]. PMID- 4163696 TI - Embryology of the thyrotroph. PMID- 4163697 TI - On the immunological nature of the long acting thyroid stimulator. PMID- 4163698 TI - An attempt to establish a test for thyrotropin (TSH) reserve. PMID- 4163699 TI - Electrophoretic evidence for the presence of an estrogen-binding beta-globulin in human plasma. PMID- 4163700 TI - Effect of maternal ingestion of iophenoxic acid (Teridax) on protein-bound iodine: report of a family. PMID- 4163701 TI - Transformations in glycyrrhetinic acid: rearrangement of ring A. PMID- 4163702 TI - A neutrophil cycle in healthy individuals. PMID- 4163703 TI - [Possibility of errors in the diagnosis of Toxoplasma gondii in a hemogram]. PMID- 4163704 TI - Diffuse thinning of hair in iodide-induced hypothyroidism. PMID- 4163705 TI - Follicular hyperkeratosis and ocular abnormalities associated with Fairbank's syndrome. PMID- 4163706 TI - Diagnosis of gonorrhea by a fluorescent antibody technique. PMID- 4163707 TI - Polycyclic aromatic hydrocarbons in common Japanese foods. I. Broiled fish, roasted barley, shoyu, and caramel. PMID- 4163708 TI - Studies of human anti-gamma-globulin factors reacting with pepsin-digested gamma globulins. AB - Many sera from normal individuals as well as patients with various disease states contain agglutinating antibodies which show specificity for antigenic determinants of gamma-globulin revealed by pepsin digestion at pH 4.1. Sera containing such agglutinating activity as well as sera negative for these agglutinators contain low molecular weight (3S-5S) components of slow gamma mobility which inhibit these agglutination reactions. Low molecular weight inhibitors show both auto- and isospecificity, and are antigenically related to the 5S pepsin fragment of gamma-globulin. A common situation is thereby revealed in which human anti-gamma-globulin antibodies showing specificity for pepsin digested gamma-globulins are present in serum along with low molecular weight gamma-globulin components capable of inhibition. Autoreactivity or autospecificity of such anti-gamma-globulin factors is a phenomenon shared by both normal human sera and sera from patients with various disease states. PMID- 4163709 TI - Studies on rabbit lymphocytes in vitro. V. The induction of blast transformation with sheep antisera to rabbit IgG subunits. AB - The addition of sheep antisera to rabbit IgG or to rabbit IgG subunits (L chain, H chain, Fab piece, Fc piece) to in vitro cultures of rabbit peripheral lymphocytes may induce up to 80-90% of the small lymphocytes to transform into immature "blast" cells. As many as 1 x 10(7) molecules of antibody may be required to stimulate each cell. It is concluded that each peripheral lymphocyte carries the antigenic specificities of the entire IgG molecule and thus could carry, and may produce specific antibody molecules. Such a conclusion supports the theory that the small lymphocyte may be the site of specific recognition of antigens in the primary response. PMID- 4163710 TI - Heavy chain subclasses of human gamma G-globulin. Serum distribution and cellular localization. AB - Two antigenic types of naturally occurring proteins related to the papain produced F(c) fragment of gammaG-globulin have been studied. Most normal and myeloma gammaG-globulins are related to one or the other of these proteins, based on antigenic and structural characteristics of their heavy chain. Molecules bearing the determinant "Cr" are approximately 10 times as abundant as those bearing the determinant termed "Zu" in pools of normal gammaG-globulin and among a large group of gammaG-myeloma globulins. Both populations have properties of typical gammaG-globulin antibodies. Splenic cells, stained for these two populations with specific fluorescent antibody preparations, are found to contain one or the other of the two populations of gammaG-globulin, but not both. Approximately 10 times as many cells contain the Cr determinant as contain the Zu determinant. PMID- 4163711 TI - Thyromimetics. V. The synthesis and biological screening of alpha methylthyroxine. PMID- 4163712 TI - [Study of the rheumatoid factor. Its reactivity with gamma globulin in several animals]. PMID- 4163713 TI - [Purification and immunological studies of bovine serum beta-globulin having the identical complement activity with mouse beta-globulin regulated by a single gene]. PMID- 4163714 TI - Overhead projectors in nurse training. PMID- 4163715 TI - Purification and activity of growth-promoting alpha-globulin for cells in cultures. PMID- 4163716 TI - [Field method for the evaluation of sensitivity of flies to gamma hexachlorocyclohexane]. PMID- 4163717 TI - [Differentiation of sensitivity of Pediculus humanus humanus L. to the organochlorine insecticides in relation to physiological and environmental conditions. 3. Effects of environmental conditions (temperature, humidity) and density of population on the sensitivity of louse to p,p'-DDT and gamma HCH]. PMID- 4163718 TI - Use of the silver-hydroquinone sequence for the display of reticular fibers. PMID- 4163719 TI - Pollen tube mitosis in culture; osmotic control and acenaphthene treatment. PMID- 4163720 TI - Rapid demonstration of juxtaglomerular granules in mammals and birds. PMID- 4163721 TI - A resinous mounting medium compatible with azo-dye staining for alkaline phosphatase. PMID- 4163722 TI - A convenient method for processing fetuses for skeletal staining. PMID- 4163723 TI - Erythema nodosum. PMID- 4163724 TI - Erythema chronicum migrans (Afzelii) associated with mosquito bite. PMID- 4163725 TI - Some immunological properties of guinea pig skin-saline suspension. 3. Skin lesions produced in guinea pigs by rabbit dermatotoxic serum. PMID- 4163726 TI - Sensitization to the neomycin group of antibiotics. Patterns of cross-sensitivity as a function of polyvalent sensitization to different portions of the neomycin molecule. PMID- 4163728 TI - Cytochemical reactions of basophil leukocytes. V. Sudan black B staining. PMID- 4163727 TI - Specific fluorescence in guinea-pig melanocytes. PMID- 4163729 TI - Processing cryostat sections of formalin-fixed tissues. PMID- 4163730 TI - Rapid fluorescein and protein assay method for fluorescent-antibody conjugates. AB - A method is presented for the rapid determination of the fluorescein content, protein content, and fluorescein-to-protein ratio for immune globulin conjugates with fluorescein isothiocyanate as the fluor. This method is based on the absorbance of the fluorescent antibody at those wavelengths primarily associated with the fluorescein and gamma-globulin fractions, and permits these materials to be determined by a single nondestructive analytical procedure. A small sample of the fluorescent antibody, in many cases 0.1 ml or less, is adequate for the above determinations. A nomograph is presented which allows simultaneous determination of the materials from the observed absorbance at the two wavelengths. The method is sufficiently accurate for most applications of the fluorescent-antibody techniques. Although this procedure has been developed primarily for fluorescent antibody conjugates prepared from rabbit gamma-globulin, it can be used directly for antibodies prepared from other animals provided the gamma-globulin is relatively free from albumin. PMID- 4163731 TI - [Immunoelectrophoretic studies on proteinuria in children affected by Cooley's disease]. PMID- 4163732 TI - Appearance of pre-alpha-2-globulins soon after the very first dose of diphtheria toxoid in horse. PMID- 4163733 TI - A simple technique for the preservation of vital dyes in fixed and sectioned embryos. PMID- 4163734 TI - [Immunochemical analysis of trypsin-antitrypsin antibody system]. PMID- 4163735 TI - Thyroid status in pregnancy and in women taking oral contraceptives. PMID- 4163736 TI - Venous/arterial pulmonary shunting as the principal cause of postoperative hypoxaemia. PMID- 4163737 TI - In-vitro activity of cephalothin/kanamycin and methicillin/kanamycin combinations against methicillin-resistant Staphylococcus aureus. PMID- 4163738 TI - The significance of bacteriuria in pregnancy. PMID- 4163739 TI - The long-term prognosis of severe infantile malnutrition. PMID- 4163740 TI - Blood-volume changes in severe anaemia in pregnancy. PMID- 4163741 TI - Treatment of early Hodgkin's disease. PMID- 4163743 TI - Motes and beams. PMID- 4163742 TI - Neuronal membrane patterns in memory and concussion. PMID- 4163744 TI - Monitoring of drugs. PMID- 4163745 TI - Glandular-fever cells. PMID- 4163746 TI - The health of students. PMID- 4163747 TI - Radiologists and radiation. PMID- 4163749 TI - Chromosome breakage and leukemia. PMID- 4163748 TI - Hepatic cirrhosis and diabetes mellitus. PMID- 4163750 TI - Antihistamine treatment and drug eruptions. PMID- 4163751 TI - Children and death. PMID- 4163752 TI - F.A.O. comes of age. PMID- 4163753 TI - Red eyes in renal failure. PMID- 4163754 TI - Hemodialysis in poisoning with methaqualone and diphenydramine. PMID- 4163756 TI - Walter Russell Brain. Baron Brain of Eynsham. PMID- 4163755 TI - Hematological side-effects of diazoxide. PMID- 4163758 TI - [Thyroid function in Cushing's disease. I. Studies prior to surgical treatment]. PMID- 4163757 TI - Arterial blood-gas tensions and pH in acute lower-respiratory-tract infections in infancy and childhood. PMID- 4163759 TI - [Metabolism of lipids in rats influenced by orotic acid, lipotropic factors, substances with purine nucleus, and a purified diet]. PMID- 4163760 TI - Efficacy of topically applied progestational agents. PMID- 4163761 TI - Orthotopic autotransplantation and allotransplantation of the liver: functional and structural patterns in the dog. PMID- 4163762 TI - The nature of the "basement membrane" in human gingiva. PMID- 4163763 TI - Induction of proliferative synovitis in rabbits by intra-articular injection of immune complexes. PMID- 4163764 TI - Long-term culture of lymph node tissue from a patient with lymphocytic lymphoma. II. Preliminary ultrastructural, immunofluorescence and cytogenetic studies. PMID- 4163765 TI - Observations on the deposition, structure, and cytochemistry of the jelly envelopes of the egg of the newt, Triturus viridescens. PMID- 4163766 TI - Intrathyroidal exchangeable iodine in endemic goiter in Misiones, Argentina. PMID- 4163767 TI - Protein-bound iodine level during childhood and adolescence. PMID- 4163768 TI - Acceleration of thyroxine and triiodothyronine turnover during bacterial pulmonary infections and fever: implications for the functional state of the thyroid during stress and in senescence. PMID- 4163769 TI - Modern developments in teaching methods. PMID- 4163770 TI - Electrophoretic mobilities of serum gamma-glutamyl transpeptidase and its clinical application in hepatobiliary disease. PMID- 4163771 TI - Conservative resection in surgery for bronchogenic carcinoma. PMID- 4163772 TI - Experience with palliative resection and irradiation therapy for carcinoma of the lung. PMID- 4163773 TI - Dermal connective tissue in patients with chronic obstructive airways disease. PMID- 4163774 TI - Gastric function in patients with gastric carcinoma. PMID- 4163775 TI - Treatment of urinary schistosomiasis with niridazole (Ambilhar) in 576 African schoolchildren. PMID- 4163776 TI - Haemophilus influenzae precipitins in the serum of patients with chronic bronchial disorders. PMID- 4163777 TI - Capsulated Haemophilus influenzae and respiratory-tract disease. PMID- 4163778 TI - Rapid rise of insulin concentration in the plasma after intravenous administration of sodium tobutamide. PMID- 4163779 TI - Need for glucagon in severe hypoglycaemia induced by sulphonylurea drugs. PMID- 4163780 TI - Microscopy of the cancer cell as a guide to cancer chemotherapy. PMID- 4163781 TI - Epilepsy and driving. PMID- 4163782 TI - A day hospital for disturbed children under five. PMID- 4163783 TI - Serological investigations in suspected brucellosis. PMID- 4163784 TI - [Clinical use of eviprostat for hypertrophy of prostate]. PMID- 4163785 TI - Effect of interhemispheric transection on the EEG patterns in sleep and wakefulness in monkeys. PMID- 4163786 TI - Morphological and chemical studies of Nauta-stained degenerating cerebellar and hypothalamic fibers. PMID- 4163787 TI - Spinal afferents to the lateral reticular nucleus. I. An histological study. PMID- 4163788 TI - Cytoarchitectonic study of the isocortex in the sloth (Choloepus hoffmanni Peters). PMID- 4163789 TI - Patterns and mode of termination of cerebellar cortico-nuclear pathways in the monkey (Macaca mulatta). PMID- 4163790 TI - Observations of the development of the nucleus of Edinger-Westphal in man and the albino rat. PMID- 4163791 TI - The naso-temporal division of the cat's retina. PMID- 4163792 TI - The projection of the cat's retina on the lateral geniculate nucleus. PMID- 4163793 TI - Muliaxonal autonomic junctions in intestinal smooth muscle of the toad (Bufo marinus). PMID- 4163794 TI - [Macroscopic studies of heart conduction system - with special references to PAS method]. PMID- 4163795 TI - Vaccinia Gangrenosa with normal humoral antibodies. A case possibly due to deficient cellular immunity treated with N-methylisatin beta-thiosemicarbazone (Compound 33T57, Marboran). PMID- 4163796 TI - Localized scleroderma. A histochemical and chemical study. PMID- 4163797 TI - Purpura hyperglobulinemia. PMID- 4163798 TI - Comparison between FA factor and LE cell tests. PMID- 4163799 TI - Malacoplakia. Discussion of pathogenesis and report of three cases including one of fatal gastric and colonic involvement. PMID- 4163800 TI - Effect of actinomycin on the synthesis of macromolecules in Escherichia coli. PMID- 4163801 TI - Stimulation of polypeptide synthesis by artificial nucleoproteins. PMID- 4163802 TI - [Triosorb test in various diseases]. PMID- 4163803 TI - [Thyroid gland]. PMID- 4163804 TI - No more measles? PMID- 4163805 TI - Some urological aspects of 93 consecutive renal homotransplants in modified recipients. PMID- 4163806 TI - The effect of bilateral adrenalectomy on induced benign prostatic hyperplasia in mice. PMID- 4163807 TI - [Effect of prednisolone and glycyrrhizin on passive transfer in experimental allergic encephalomyelitis]. PMID- 4163808 TI - [Antigenic structure of penicillin]. PMID- 4163809 TI - Widely distributed necrotic arterial lesions induced in rabbits by experimental renal alterations. VI. Demonstration of antigenic determinants of gamma-globulin and of thrombin-clottable plasma protein in arterial lesions: uptake of guinea pig complement in vitro. PMID- 4163810 TI - Succinylation of gamma globulin. PMID- 4163811 TI - Stable bromine and activation analysis in protein tracer studies. PMID- 4163812 TI - The elusive trigger mechanism of endotoxin shock. PMID- 4163813 TI - Interglobular dentine and the calcospherite pattern. PMID- 4163815 TI - Production of alpha-1-globulins by the perfused rat liver. PMID- 4163814 TI - The cytopathic action of purified staphylococcal delta-hemolysin. PMID- 4163817 TI - The frequency and pattern of normal tremor. PMID- 4163816 TI - Refsum's disease. PMID- 4163818 TI - Inhibition of visual evoked responses to patterned stimuli during voluntary eye movements. PMID- 4163819 TI - Non-primary sensory projections on the fronto-orbital cortical area in the cat. PMID- 4163820 TI - EEG synchronization induced by high frequency midbrain reticular stimulation in anesthetized cats. PMID- 4163821 TI - Changes in electrical activity of the cerebral cortex and of some subcortical centers in hyperbaric oxygen. PMID- 4163822 TI - Relationships between EEG patterns and arterial pressure changes. PMID- 4163823 TI - Vestibular influences upon the EEG of epileptics. PMID- 4163824 TI - EEG findings in late infantile metachromatic and globoid cell leucodystrophy. PMID- 4163826 TI - Observations on high frequency electroencephalograms. PMID- 4163825 TI - Diagnostic recording of somato-sensory cortical evoked potentials in man. PMID- 4163827 TI - Intrinsic and induced EEG rhythms in severe hypothyroidism secondary to panhypopituitarism. A case report. PMID- 4163828 TI - An averaging method for determination of temporal relationship between epileptogenic foci. PMID- 4163829 TI - Monopolar rheoencephalography. PMID- 4163830 TI - New subminiature amplifier-transmitters for telemetering biopotentials. PMID- 4163831 TI - An antaminic drug, BC 105, in the prophylaxis of migraine. Pharmacological, clinical, and therapeutic experiences. PMID- 4163832 TI - Quantitative immunoglobulin levels (IgG, IgA and IgM) in children. PMID- 4163833 TI - Experimental eosinophilia. IX. Effects of immunosuppressive agents on eosinophil cell responses. PMID- 4163834 TI - Studies on the radiosensitive phase of the primary antibody response in rabbits. I. The role of the macrophage. PMID- 4163835 TI - Application of the paired label radioantibody technique to tissue sections and cell smears. PMID- 4163836 TI - Antibodies against human leukemia cell lines. PMID- 4163837 TI - Tumors in amphibians. I. Histology of a neuroepithelioma in Siredon mexicanum. PMID- 4163838 TI - A simple immunoelectrophoretic method for demonstrating deficiency of the beta-1A C component of complement in serum. PMID- 4163839 TI - Combining the antidepressant drugs. PMID- 4163840 TI - Abdominal wound disruption. PMID- 4163841 TI - [Experiences with epsilon-aminocaproic acid in electroresection of the prostate]. PMID- 4163842 TI - [Diagnosis and therapy of prostatic diseases in advanced age]. PMID- 4163843 TI - Immunoglobulins. PMID- 4163844 TI - Some studies on the effects of radiation and radiation modifiers on growing hair. PMID- 4163846 TI - [Biosynthesis of protein (immunoglobulin)]. PMID- 4163845 TI - [Research on thyroid function in female phenotype gonadal dysgenesis]. PMID- 4163847 TI - [Immunopathology of rheumatoid arthritis]. PMID- 4163848 TI - [Distribution of biologically active groups in gamma globulin molecules]. PMID- 4163849 TI - Peritoneal atrial shunt for intractable ascites. PMID- 4163850 TI - Preparation of nonthrombogenic plastic surfaces. PMID- 4163851 TI - Transrectal needle biopsy of the prostate. PMID- 4163852 TI - Geriatric surgery. Immediate postoperative care and treatment with special reference to cardiovascular, cerebral, and pulmonary complications. PMID- 4163853 TI - Panorama of surgical diseases in the aged. PMID- 4163854 TI - Geriatric urology. PMID- 4163855 TI - Results of geriatric surgery. PMID- 4163856 TI - Ten years' experience of geriatric aspects in surgery of patients with benign prostatic hyperplasia. PMID- 4163857 TI - Vital staining of the canaliculus lacrimalis and the palpebral border (Marx' line). PMID- 4163858 TI - Studies in oral leukoplakias. 10. Periodic-acid-Schiff staining of normal and leukoplakic epithelium before and after vitamin A application. PMID- 4163859 TI - Histologic parallels between mastocytoma and melanoma. Demonstration of melanin in tumor cells of mastocytoma and metachromasia in tumor cells of melanoma. PMID- 4163860 TI - The role of soluble aggregates in the primary immune response of mice to human gamma globulin. PMID- 4163861 TI - The loss of phenotypic traits by differentiated cells. 3. The reversible behavior of chondrocytes in primary cultures. AB - Observations were made on the behavior of chondrocytes grown under various conditions in vitro. The chondrocytes in 10-day embryonic chick vertebrae were grown as cultures of intact vertebrae, as pellets of chondrocytes liberated from their matrix, and as monodispersed cells plated out on plasma clots. Cartilage matrix was stained metachromatically with toluidine blue. Radioautographs were made of incorporated H(3)-thymidine, H(3)-proline, and S(35)-sulfate to determine the extent of DNA synthesis, collagen synthesis, and chondroitin sulfate synthesis, respectively. Chondrocytes in intact vertebrae or in pellets are rounded and actively synthesizing chondroitin sulfate and collagen. There is little DNA synthesis by cells in either vertebrae or pellets. Chondrocytes grown as monodisperse cells rapidly cease synthesizing cytologically detectable chondroitin sulfate and are induced to synthesize DNA and divide. There is a change in the shape of these chondrocytes from a rounded to a more stellate condition which accompanies the shift in metabolic activity. Conversely, when the cells attain a certain cell density, they reacquire a rounded shape, cease dividing, and again synthesize chondroitin sulfate. Clusters of chondrocytes synthesize more chondroitin sulfate than isolated chondrocytes. It is concluded that most chondrocytes synthesizing chondroitin sulfate do not concurrently synthesize DNA. Interaction between associated chondrocytes is important in inducing and maintaining chondroitin sulfate synthesis in genetically determined chondrocytes. Failure of interaction between chondrocytes leads to DNA synthesis and cell multiplication. PMID- 4163862 TI - Some aspects of the structural organization of the myofibril as revealed by antibody--staining methods. AB - FROM OBSERVATIONS OF FLUORESCENT ANTIBODY STAINING AND ANTIBODY STAINING IN ELECTRON MICROSCOPY, EVIDENCE IS PRESENTED FOR THE FOLLOWING: (a) Direct contact of the actin and myosin filaments occurs at all stages of contraction. This results in inhibition of antibody staining of the H-meromyosin portion of the myosin molecule in the region of overlap of the thin and thick filaments. (b) Small structural changes occur in the thick filaments during contraction. This leads to exposure of antigenic sites of the L-meromyosin portion of the myosin molecule. The accessibility of these antigenic sites is dependent upon the sarcomere length. (c) The M line is composed of a protein which is weakly bound to the center of the thick filament and is not actin, myosin, or tropomyosin. (d) Tropomyosin as well as actin is present in the I band. (e) If actin or tropomyosin is present in the Z line, it is masked and unavailable for staining with antibody. PMID- 4163863 TI - The fine structure of the ribonucleoprotein in bacterial cytoplasm. PMID- 4163864 TI - Studies on thyroid function in malnourished infants and children in Egypt. PMID- 4163865 TI - [Mode of action and biologic effects of steroid inhibitors of ovulation]. PMID- 4163866 TI - A simple method of preparing protein-erythrocyte conjugates for hemagglutination tests. PMID- 4163867 TI - Sites of production of primate serum proteins associated with complement system. PMID- 4163868 TI - Comparative immunology. Active immunization of young alligators with hemocyanin. PMID- 4163869 TI - Specific heterophile antibody from infectious mononucleosis serum. PMID- 4163870 TI - Reduced biological effectiveness of orally administered L-thyroxine in the rat in the presence of blood plasma. PMID- 4163871 TI - Eosinophils and histamine in Asboe-Hansen's disease (incontinentia pigmenti). Studies with the skin window technique. PMID- 4163872 TI - Immunoelectrophoretic study of biological false positive serum reactions for syphilis. PMID- 4163873 TI - [DMSO as an inhibitor of the anaphylactoid reaction produced by dextran]. PMID- 4163874 TI - The effect of prolonged thiazide administration on thyroid function. PMID- 4163875 TI - Systemic lupus erythematosus and multiple sclerosis in identical twins. PMID- 4163876 TI - Fine structure of meiotic chromosomes. Comparative study of nine species of insects. PMID- 4163877 TI - Release of histamine into gastric venous blood following injury by acetic or salicylic acid. PMID- 4163878 TI - An in-service training program for dietary employees. PMID- 4163879 TI - Rabbit macrophage interferons. I. Conditions for biosynthesis by virus-infected and uninfected cells. AB - Interferon is produced in cultures of rabbit leukocytes in response to infection with Newcastle disease virus or in the absence of known viral infection. The macrophage appears to be the responsible producing cell. Cultures prepared from sterile peritoneal exudates, which contained about 90% macrophages, are at least as efficient as cultures of rabbit kidney (RK) cells in their capacity to synthesize NDV-induced interferon. Interferon can be detected in the medium by 2 hr after viral infection and the titers usually reach a peak of 10,000 PDD(50)/ml by 4-6 hr. Exposure to actinomycin prior to or shortly after viral induction effectively blocks interferon synthesis by cells of both types. However, macrophages become refractory to actinomycin by 30-60 min compared with 607-120 min for RK cells, a finding which suggests earlier and more rapid transcription of interferon-specific messenger RNA in macrophages. Macrophages harvested from the peritioneal cavity of rabbits injected intravenously with NDV 48 hr previously also exhibit slightly reduced capacity to synthesize interferon, but this tolerant state is less marked than is tolerance to production of circulating interferon in intact rabbits. Interferon is also synthesized by rabbit macrophages not infected with virus but simply incubated at 37 degrees C in medium with or without added bacterial endotoxin. Uninfected polymorphonuclear leukocytes, rabbit kidney and spleen cells produced no detectable interferon under similar conditions of cultivation. No interferon was released by intact macrophages incubated at 4 degrees C or by ultrasonically disrupted macrophages incubated at 37 degrees C. Although interferon titers were found to be higher when uninfected cultures were exposed to 10-100 microg/ml of E. coli lipopolysaccharide, unavailability of suitable pyrogen-free maintenance media precluded answering the question whether macrophages can continually synthesize and release interferon spontaneously. Interferon yields from uninfected macrophages were only 1% or less of the yields from NDV-infected macrophages, but the rates of synthesis were similar under both conditions. Studies with actinomycin and puromycin revealed that sequential transcriptive and translational events are required for de novo interferon synthesis by uninfected cells in a manner similar to virus-induced interferon synthesis. The physical properties and molecular weights of these rabbit interferons are discussed in the following report (12). PMID- 4163880 TI - Histamine releasers. I. Structure of the dimer formed from p-methoxy-N methylphenethylamine and formaldehyde. PMID- 4163881 TI - Voluntary male sterilization. PMID- 4163882 TI - Studies with radioactive copper (64Cu and 67Cu) in relation to the natural history of Wilson's disease. PMID- 4163883 TI - Immunoglobulin synthesis within the central nervous system in disseminated sclerosis. PMID- 4163884 TI - A self-releasing inferior vena caval clip. PMID- 4163885 TI - Creation of atrial septal defects by balloon catheter in babies with transposition of the great arteries. PMID- 4163886 TI - Antibiotic-resistant streptococci in the mouths of children treated with penicillin. PMID- 4163887 TI - Fatal granulomatous disease of childhood and benign lymphocytic infiltration of the skin (congenital dysphagocytosis). PMID- 4163888 TI - Hypothermia in kwashiorkor. PMID- 4163889 TI - Gallstones, gastric secretion, and flatulent dyspepsia. PMID- 4163890 TI - The performance of nasal catheters and a face mask in oxygen therapy. PMID- 4163891 TI - Hypofibrinogenaemia without increased fibrinolysis in leukaemia. PMID- 4163892 TI - Leucocyte-excretion rate as a screening test for bacteriuria. PMID- 4163893 TI - Treatment of primary biliary cirrhosis with azothioprine. PMID- 4163894 TI - Metabolic precursors of methylmalonic acid in vitamin-B12 deficiency. PMID- 4163895 TI - Tedium and the law of diminishing returns in clinical biochemistry laboratories. PMID- 4163896 TI - Joseph Bamforth. PMID- 4163897 TI - Abnormal urinary steroid excretion and subsequent breast cancer. A prospective study in the Island of Guernsey. PMID- 4163898 TI - Fasting blood-sugar and serum-growth-hormone in hypopituitary diabetics. PMID- 4163899 TI - Effect of coffee on glucose tolerance and circulating insulin in men with maturity-onset diabetes. PMID- 4163900 TI - Subjective assessment and objective measurement of finger clubbing. PMID- 4163901 TI - A controlled trial of artificial respiration in the respiratory-distress syndrome of the newborn. PMID- 4163902 TI - A simple scoring system for classifying the severe forms of protein-calorie malnutrition of early childhood. PMID- 4163903 TI - Addison's disease and Addisonian anaemia. PMID- 4163904 TI - Precipitating antibodies to aspergillus fumigatus in cystic fibrosis. PMID- 4163905 TI - A simple method for determining selectivity of proteinuria. PMID- 4163906 TI - Measles-virus antibody and antigen in subacute sclerosing panencephalitis. PMID- 4163908 TI - Epithelial changes in the uterine cervix. PMID- 4163907 TI - Effect of intrinsic factor on absorption of vitamin B12 from small intestine. PMID- 4163909 TI - Efficient use of blood. PMID- 4163910 TI - A defence against viruses. PMID- 4163911 TI - A unique endeavour. PMID- 4163912 TI - Another kind of measles encephalitis? PMID- 4163913 TI - The handicapped child at school. PMID- 4163914 TI - Central action of chlorpromazine. PMID- 4163915 TI - A controlled trial of inpatient and outpatient treatment of alcohol dependency. PMID- 4163916 TI - Resident hospital doctors' families. PMID- 4163917 TI - Pet meat as a potential source of human salmonellosis. PMID- 4163918 TI - Medical ethics today. A student's uncertainties. PMID- 4163919 TI - From medical science to medical care. Public policy, the resultant of private policies. PMID- 4163920 TI - Hereditary coproporphyria. PMID- 4163921 TI - Antibodies in the families of thyrotoxic patients. PMID- 4163922 TI - Streptococcus pyogenes, type 49. A nephritogenic Streptococcus with a wide geographical distribution. PMID- 4163923 TI - Blood-gas tensions in bronchial asthma. PMID- 4163924 TI - Multiple serotypes of vibrio cholerae isolated from a case of cholera. Evidence suggesting in-vivo mutation. PMID- 4163925 TI - Autoimmunity in gonadal dysgenesis and Klinefelter's syndrome. PMID- 4163927 TI - Acid and bicarbonate secretion in health and disease. PMID- 4163926 TI - In-vitro variation of viscosity of body fat during cooling. PMID- 4163928 TI - Salt loading as a possible factor in the production of potassium depletion, rhabdomyolysis, and heat injury. PMID- 4163929 TI - Flexible renal grid-sling for localising stones during lithotomy. PMID- 4163930 TI - Diagnostic tests in the porphyrias. PMID- 4163931 TI - Adult coeliac disease and neuropathy. PMID- 4163932 TI - Evaluation of a method of prescribing drugs in hospital, and a new method of recording their administration. PMID- 4163933 TI - Measurement and control of drug-administration incidents. PMID- 4163934 TI - National or personal health service? PMID- 4163935 TI - Jaundice and oral contraceptives. PMID- 4163936 TI - Cerebral thrombosis and oral contraception. PMID- 4163938 TI - Aspirin for young children. PMID- 4163937 TI - Barbiturate poisoning. PMID- 4163939 TI - Fatal benzene exposure by glue-sniffing. PMID- 4163940 TI - Effect of phosphate supplements in patients with fractures. PMID- 4163941 TI - Quantitative radiological and histological studies of the thymus in thyroid disease. PMID- 4163942 TI - Placental transfer of gastric antibodies. PMID- 4163943 TI - Haemophilia Bm: a new type of factor-IX deficiency. PMID- 4163944 TI - Effect of strenuous and graded exercise on fibrinolytic activity. PMID- 4163945 TI - Primary hypomagnesaemia with secondary hypocalcaemia in an infant. PMID- 4163946 TI - Partial-thickness skin grafting of fingertip injuries. PMID- 4163948 TI - Magnesium and malnutrition. PMID- 4163947 TI - The masking of antigens on trophoblast and cancer cells. PMID- 4163949 TI - The thymus gland and autoimmunity. PMID- 4163950 TI - International classification of tumours. PMID- 4163951 TI - Fingertip injuries. PMID- 4163952 TI - Management of phaeochromocytoma. PMID- 4163953 TI - Myotonia produced by an unknown humoral substance. PMID- 4163954 TI - [Prophylaxis of viral infectious hepatitis with gamma-globulin]. PMID- 4163955 TI - [Study of certain constituents of the beta-globulin group in the human umbilical cord blood. Comparative study with the maternal blood]. PMID- 4163956 TI - [Gamma globulins and rubella]. PMID- 4163957 TI - Palliative treatment of metastatic carcinoma of the liver by hepatic artery infusion with 5-fluorouracil: report of a case. PMID- 4163958 TI - Leiomyosarcoma of the bladder: case report with autopsy. PMID- 4163959 TI - Influence of prior sensitization with mycobacteria on antibody response to protein antigen in Freund's adjuvants. PMID- 4163960 TI - Antibodies to corticotrophin and their relation to adrenal function in children receiving corticotrophin therapy. PMID- 4163962 TI - Molecular size of gamma-A-immunoglobulin from bronchial secretions. PMID- 4163961 TI - Increase in RNase and DPNase activities in ascites tumor cells induced by various cytostatic agents. PMID- 4163964 TI - Slide projection for small groups. PMID- 4163963 TI - Simple test for insulin antibodies in sera, using 131-I-insulin and ethanol precipitation. PMID- 4163965 TI - Immunoglobulins in the conjunctiva. PMID- 4163966 TI - Relationship between ragweed-reagins and serum immunoglobulins. PMID- 4163967 TI - Characterization of rat IgA and its non-identity with the anaphylactic antibody. PMID- 4163968 TI - Relationship of normal human serum immunoglobulins to blocking of Prausnitz Kustner sensitization. PMID- 4163969 TI - Evidence that the two ribosomal RNA species of plant tissue are synthesized on different genetic loci. PMID- 4163970 TI - Comparative study between immunoglobulin status and interferon response in health and disease. PMID- 4163971 TI - The binding of immune globulins and other proteins by polystyrene latex particles. PMID- 4163972 TI - Endomyocardial fibrosis in Europeans resident in tropical Africa. PMID- 4163973 TI - Skin flora of the newborn. PMID- 4163974 TI - Simple goitre in Glasgow and Dumfries schoolchildren. PMID- 4163975 TI - Effects of octanoic acid on serum-levels of free fatty acids, insulin, and glucose in patients with cirrhosis and in healthy volunteers. PMID- 4163976 TI - Therapeutic hazards of phenylbutazone and oxyphenbutazone in polymyalgia rheumatica. PMID- 4163977 TI - Immunological studies in endomyocardial fibrosis and other forms of heart-disease in the tropics. PMID- 4163978 TI - Intravascular haemolysis and disseminated intravascular coagulation. PMID- 4163979 TI - Hypoglycaemic effect of adipose-tissue extracts in adrenalectomised rats. PMID- 4163980 TI - Bacterial endocarditis: a changing pattern. PMID- 4163981 TI - Capsulated haemophilus influenzae. PMID- 4163982 TI - Pneumocystis carinii pneumonia. PMID- 4163983 TI - Oxygen by face mask and nasal catheter. PMID- 4163984 TI - Inotropic effect of quinidine. PMID- 4163985 TI - Significance of disappearance-rate of injected insulin. PMID- 4163986 TI - Potassium, glucose, and insulin in myocardial infarction. PMID- 4163987 TI - Testing for hypoparathyroidism. PMID- 4163988 TI - Serum-creatine-phosphokinase levels. PMID- 4163989 TI - Phenylthiocarbamide and mental immaturity. PMID- 4163990 TI - Small-bowel changes in ichthyosis. PMID- 4163991 TI - Haematological effects of methyldopa. PMID- 4163992 TI - Glandular-fever cells. PMID- 4163993 TI - Erythrocyte lipids in Tay-Sachs disease. PMID- 4163994 TI - Propranolol and hypoglycaemia. PMID- 4163995 TI - [Role of the serum complement in the pathogenesis of the LE phenomenon]. PMID- 4163996 TI - Histochemical observations on the lipids of carious human dentine. PMID- 4163997 TI - Electron microscopic identification of autonomic nerve endings. PMID- 4163998 TI - Location of spore and vegatative antigens of Bacillus cereus by means of ferritin labelled antibodies. PMID- 4163999 TI - [Specific human anti-gamma globulin antibodies of the Gm system in multiply transfused patients]. PMID- 4164001 TI - Systemic lupus erythematosus. PMID- 4164000 TI - [Aspects of tetanic toxigenicity]. PMID- 4164002 TI - Determination of serum thyroxine. The diagnostic value in thyroid diseases. PMID- 4164003 TI - [Improvement of the method of staining of glia fibers]. PMID- 4164004 TI - Cultured mammalian cell deoxyribonucleic acid as a template for in vitro protein synthesis. PMID- 4164005 TI - Interaction of 14C-labeled human and bovine growth hormone with serum proteins. PMID- 4164006 TI - Bacterial antigens and aggregated gamma globulin in the lesions of nodular vasculitis. PMID- 4164007 TI - Autosensitization and multiple sclerosis. PMID- 4164008 TI - Thyroid activity in mice with hypothalamic lesions induced by goldthioglucose. PMID- 4164009 TI - Studies on the mechanism of action of liver extracts in inhibiting uptake of 131 I in vitro by the rat thyroid gland. PMID- 4164010 TI - The microcrystalline structure of cellulose in cell walls of cotton, ramie, and jute fibers as revealed by negative staining of sections. AB - With a new technique of negative staining of sections, it has been possible to observe directly, in ultrathin sections under the electron microscope, the original microcrystalline and microfibrillar structure of cellulose as it occurs in living cells. This method has advantages over the study of isolated fibers used so far by others, in that the original arrangement of microfibrils is better preserved, and their collapse into larger fibrillar units is prevented. With this method, the cell walls of ramie, jute, and cotton fibers have been studied. The size (diameter, 25 to 40 A) and the longitudinal periodicity observed in the single microfibrils and the orientation and spatial arrangement of the microcrystallite within the microfibrils are found to correspond with the latest models derived by others from data obtained by indirect methods such as X-ray diffraction. The microfibril size of about 35 A, found by measuring these structures in sections, agrees with the latest conclusions reached by others in recent work with isolated fibrils. PMID- 4164011 TI - The importance of osmiophilia in the production of stable azoindoxyl complexes of high contrast for combined enzyme cytochemistry and electron microscopy. PMID- 4164012 TI - The effect of trypan blue on the postnatal development of serum proteins. PMID- 4164013 TI - [Contribution to the "Refsum's syndrome" retinopathia pigmentosa in hereditary enzymopathy of lipid metabolism]. PMID- 4164014 TI - [Studies on cell cultures in the rabbit cornea]. PMID- 4164015 TI - Mitigation of secondary disease in mice receiving bone marrow from donors pretreated with cortisone and alkylating agents. PMID- 4164016 TI - [Effects of metandiennone (Geabol, Dianabol) on pituitary function]. PMID- 4164017 TI - Observations on the relationship between the maximal thyroxine binding capacities of thyroxine-binding interalpha globulin and thyroxine-binding prealbumin, the serum protein bound iodine concentration and sexual maturity in adolescents. PMID- 4164018 TI - Compartmentalization and turnover of 131-I-labeled albumin and gamma globulin in horses. PMID- 4164019 TI - Microscopic anatomy of the integument of adult swine. PMID- 4164020 TI - Chemotherapy of renal leptospirosis in hamsters. PMID- 4164021 TI - The problem of the coronary changes due to disturbance of vascular wall permeability. PMID- 4164022 TI - Disc electrophoretic studies of human perilymph. PMID- 4164023 TI - Innervation of the human cochlea. PMID- 4164024 TI - [Binding of proflavin and actinomycin on deoxyribonucleic acid. II. Binding on denaturated and single strand DNA, apyrimidic acid and apurinic acid]. PMID- 4164025 TI - Modification of stress responses in histamine-depleted rats. PMID- 4164026 TI - [Studies on durable long term preservation of stained preparations of Treponema pallidum. Experiment I. Detection of Treponema pallidum in testes of syphilitic rabbits by fluorescent antibody reaction]. PMID- 4164027 TI - A cytocidal system in normal human serum active against Ehrlich Lettre ascites tumor cells. I. Identification of the components of the system and site of attachment. PMID- 4164028 TI - Histological demonstration of mucosal invasion by Giardia lamblia in man. PMID- 4164029 TI - Ultrastructural studies of the human Giardia lamblia and subjacent jejunal mucosa in a subject with steatorrhea. PMID- 4164030 TI - Some biological activities associated with the 10S form of human gamma-G globulin. PMID- 4164031 TI - Inhibition of the anti-globulin reaction by human immunoglobulin G and its fragments. PMID- 4164032 TI - Bacteriostatic effects of horse sera and serum fractions on Clostridium welchii Type A, and the abolition of bacteriostasis by iron salts. PMID- 4164033 TI - Electrophoretic studies of the conversion products of serum beta-1C-globulin. PMID- 4164035 TI - Oral pathology in focus. PMID- 4164034 TI - Quantitative studies of immunofluorescent staining. I. Analyses of mixed immunofluorescence. PMID- 4164036 TI - Magnesium starvation of Aerobacter aerogenes. IV. Cytochemical changes. AB - A number of cytochemical changes were revealed by microscopic observations of Aerobacter aerogenes populations starving for Mg(++). During the first few hours, while the synthesis of deoxyribonucleic acid (DNA) was paralleled by an increase in viable bacteria, the cells became progressively smaller. Subsequently, the number of viable cells in the culture remained constant in spite of continuing DNA synthesis, and the cells progressively elongated into filamentous forms. During this time, a second population of very small bacteria could be identified. These cells, whose number increased progressively, were inert with respect to (i) growth or reproduction when returned to a complete medium and (ii) biosynthetic activity as judged by autoradiographic estimation of uracil-H(3) incorporation into nucleic acids. When observed by electron microscopy, many thin sections from bacteria that had been starved of Mg(++) for 20 hr appeared to be almost devoid of ribosomal particles. Thionine staining indicated that the inert cells contain DNA. Furthermore, the rate of DNA synthesis in the culture corresponded to the rate of accumulation of inert cells, suggesting that their presence can account for the difference between total DNA and viable count. PMID- 4164037 TI - Influence of fixation on gross morphology of Mycoplasma. PMID- 4164038 TI - Acid treatment modification for the preparation of permanent slides of l forms and mycoplasmas. PMID- 4164039 TI - Simple method of detecting spore septum formation and synchrony of sporulation. PMID- 4164040 TI - Poly C synthetase activity in the particulate fraction of rat brain nuclei. PMID- 4164041 TI - Effective chemotherapy in children with Wilms' tumor. PMID- 4164042 TI - Morphological observations on some diphtherial phages. PMID- 4164043 TI - Cytological study of amniotic fluid with Nile blue sulphate staining. PMID- 4164045 TI - Localization of the small-intestinal disaccharidases. PMID- 4164044 TI - Alcian-PAS positive granules in mesothelioma and mesothelial cells. PMID- 4164046 TI - Anemia and cholesterolemia during estrus and pregnancy in the Beagle. PMID- 4164047 TI - Regulation of acetohydroxy and synthetase in streptomycin-dependent Escherichia coli. PMID- 4164048 TI - Regulation of acetohydroxy acid synthetase in streptomycin-dependent Escherichia coli K-12. PMID- 4164049 TI - Effects of pyridoxine deficiency and dietary cholesterol supplementation in the chick on plasma protein-bound iodine, glutamic-oxalacetic transaminase activity, and 14-C-acetate incorporation into cholesterol. PMID- 4164050 TI - [Determination of alpha-2-macroglobulin turnover in humans]. PMID- 4164051 TI - Cytochemical and chromatographic demonstration of platelet histamine release by antigen-antibody reaction in vitro. PMID- 4164052 TI - Permanent stained agar preparation of Mycoplasma and of L forms of bacteria. AB - A procedure is described that permits the preparation of permanent stained mounts of Mycoplasma and of bacterial L forms grown on the surface of and within agar media. These preparations are especially useful for making representative photographs. The cultures are fixed with Formalin vapor. Thin slices of agar are stained at elevated temperature between 50 and 60 C and at a low pH, are dried rapidly, and are mounted in Canada balsam. The results with this staining procedure are illustrated by photographs of various strains of Mycoplasma and of bacterial L forms. PMID- 4164053 TI - Evaluation of polyvinyl alcohols as semipermanent mountants for fluorescent antibody studies. PMID- 4164054 TI - Immunologic unresponsiveness to allergic thyroiditis in guinea pigs. PMID- 4164055 TI - Role of the thymus in tolerance. V. Suppressive effect of treatment with nonaggregated and aggregated bovine gamma-globulin on specific immune responses in normal adult rats. PMID- 4164056 TI - Allergen-binding activity of gamma-E, gamma-G and gamma-A antibodies in sera from atopic patients. In vitro measurements of reaginic antibody. PMID- 4164057 TI - An effect upon the regulation of gene expression: allotype suppression at the a locus in heterozygous offspring of immunized rabbits. PMID- 4164058 TI - Synthesis of human immunoglobulins in germinal centers of lymphoid organs. PMID- 4164059 TI - Enhanced immunologic sensitization of mice by the simultaneous injection of antigen and specific antiserum. 3. The role of antigen in controlling the immune response elicited with immune complexes. PMID- 4164060 TI - Interaction of rabbit anti-human H chain sera with denatured human gamma-globulin and its subunits. PMID- 4164061 TI - Interaction of rheumatoid factors with urea-denatured human gamma-globulin and its subunits. PMID- 4164063 TI - Chromosome anomalies in primary lymphoedema. PMID- 4164062 TI - Treatment of haemophilia (factor-8 deficiency) with human antihaemophilic factor prepared by the cryoprecipitate process. PMID- 4164064 TI - Role of insulin in glucose intolerance in uraemia. PMID- 4164065 TI - Bacterial L-forms in relapsing urinary-tract infection. PMID- 4164066 TI - Measurement of blood-pressure in the leg. PMID- 4164067 TI - Adrenal adenoma and hypertension. PMID- 4164068 TI - Treatment of phobic patients by systematic desensitisation. PMID- 4164069 TI - Non-specific ulcerative colitis in Bedouin Arabs. PMID- 4164070 TI - An unusual neurological manifestation of hypocalcaemia. PMID- 4164071 TI - Platelet adhesiveness in experimental scurvy. PMID- 4164072 TI - Failure of insulin response to glucose load during operation and after myocardial infarction. PMID- 4164073 TI - Foolproof tap systems for manometry. PMID- 4164074 TI - Patient demand. PMID- 4164075 TI - Anaesthetics and the heart. PMID- 4164076 TI - Streptococci and rheumatic fever. PMID- 4164078 TI - Early operation in acute piles. PMID- 4164077 TI - Crisis at adolescence. PMID- 4164079 TI - Learning to read. PMID- 4164081 TI - Epilatories and depilatories. PMID- 4164080 TI - Intravenous anaesthesia for dental surgery. PMID- 4164082 TI - The case for a new maternity-bed ratio. PMID- 4164083 TI - A national standard for anticoagulant therapy. The Manchester comparative reagent. PMID- 4164084 TI - Multiple-screening tests in Glasgow men aged over forty-five years. PMID- 4164085 TI - Voluntary eradication of brucellosis. PMID- 4164086 TI - Vinca alkaloids and salivary-gland pain. PMID- 4164087 TI - Propranolol and hypoglycemia. PMID- 4164089 TI - Immune reactions in polysaccharide media. 1. The effect of dextran on the reaction between iodine-125 labelled human serum albumin and gamma-G-globulin from rabbit anti-albumin sera. PMID- 4164088 TI - [A systematic study of 46 cases of coronary arteriosclerosis]. PMID- 4164091 TI - [Miction movement in prostatic hypertrophy observed by X-ray cineradiography]. PMID- 4164090 TI - [The amino acid composition of normal and pathological gamma globulins]. PMID- 4164092 TI - [Use of Eviprostat for treatment of prostatic hypertrophy]. PMID- 4164093 TI - Hemodynamic effects of isotonic solutions rapidly injected into the heart and great vessels. PMID- 4164094 TI - A modified Golgi-Cox method with counterstain for the study of synapses. PMID- 4164095 TI - Lipoprotein in the normal and regenerating limb tissues of the adult newt, Diemictylus viridescens. PMID- 4164096 TI - Glycogen content of preimplantation mouse embryos. PMID- 4164097 TI - [Immunoelectrophoretic studies on sera of healthy swine and swine ill with swine plague]. PMID- 4164098 TI - Preparation and some properties of antibodies with specificity toward rho nitrophenyl esters. PMID- 4164099 TI - Rubrobulbar fibres to the facial nucleus and the lateral reticular nucleus (nucleus of the lateral funiculus). An experimental study in the cat with silver impregnation methods. PMID- 4164101 TI - [A blackboard with magnetic teeth as a didactic aid in teaching students orthodontics]. PMID- 4164100 TI - [Contribution to the study of cardiac arrhythmias in childhood. (Studies on cases of the Clinica Pediatrica of the University of Bari in the period 1957-1965). II. Heterotopic rhythms]. PMID- 4164102 TI - [A negatoscope for the simultaneous reproduction of several slides or x-ray films]. PMID- 4164104 TI - The effect of phenothiazines on cerebrospinal fluid. PMID- 4164103 TI - One-pill-a-month contraceptive. PMID- 4164105 TI - The learning of double alternation by children and adults under different training procedures. PMID- 4164106 TI - The motivational effect of value symbols and competition upon problem-solving behavior in children. PMID- 4164107 TI - A diazosulfanilic acid azure A sequence for tissue protein. PMID- 4164108 TI - Studies in histochemistry. LXXXV. Histochemical demonstration of protein with bromsulfalein. PMID- 4164109 TI - Two methods for the demonstration of noradrenaline-containing adrenal medullary cells. PMID- 4164110 TI - A milk-borne infectious hepatitis epidemic. PMID- 4164111 TI - [A disorder of ganglioside metabolism with storage of ceramide lactoside, monosialo ceramide lactoside and Tay-Sachs ganglioside in the brain]. PMID- 4164112 TI - Regional distribution of some chemical structural components of the human nervous system. II. Cerebrosides, proteolipid proteins and residue proteins. PMID- 4164113 TI - [A case of amaurotic juvenile idiocy with a non-calcifying meningio-cerebral angiomatosis]. PMID- 4164114 TI - Coonhound paralysis. An acute idiopathic polyradiculoneuritis in dogs resembling the Landry-Guillain-Barre syndrome. PMID- 4164115 TI - Paternal immunoglobulin abnormalities in congenital hypogammaglobulinemia. PMID- 4164116 TI - A newly defined X-linked trait in man with demonstration of the Lyon effect in carrier females. PMID- 4164117 TI - Gastrointestinal observations in rosacea. PMID- 4164118 TI - Lymphocyte transformation in drug hypersensitivity. PMID- 4164119 TI - Variations in the frequency and form of sex chromatin in females with burns. PMID- 4164120 TI - Postoperative depression of the lymphocyte response to phytohaemagglutinin. PMID- 4164121 TI - Narrow-bore suprapubic bladder drainage in Uganda. PMID- 4164122 TI - Activity of lymphoid tissues from antilymphocyte-serum-treated mice. PMID- 4164123 TI - Characteristics in youth predisposing to fatal stroke in later years. PMID- 4164124 TI - Autoimmune reactions and virus-like particles in germ-free NZB mice. PMID- 4164125 TI - Serum gamma-G-globulin levels and gestational age in premature babies. PMID- 4164126 TI - Epidemic polyuria in man caused by a phycomycetous fungus (the Sassoon hospital syndrome). PMID- 4164127 TI - Fasting serum-triglycerides concentration and distribution of subcutaneous fat. PMID- 4164128 TI - Growth-rate in utero. PMID- 4164129 TI - What is value for money in medical care? Experiences in England and Wales, Sweden, and the U. S. A. PMID- 4164130 TI - The difficult historian. PMID- 4164131 TI - Lymphocytic activation by transfusion. PMID- 4164132 TI - Warming emergency blood-transfusions. PMID- 4164133 TI - Efficient use of blood. PMID- 4164134 TI - What is the nephrogram? PMID- 4164135 TI - Isoniazid: how much a carcinogen? PMID- 4164136 TI - Oxygen by face mask and nasal catheter. PMID- 4164137 TI - Propranolol in myocardial infarction. PMID- 4164138 TI - Propranolol in myocardial infarction. PMID- 4164139 TI - Treatment of alcohol dependency. PMID- 4164140 TI - Rickets from liquid paraffin. PMID- 4164141 TI - Benjamin William Rycroft. PMID- 4164142 TI - Induction of hepatic 7,12-dimethylbenz(alpha)anthracene metabolism by polycyclic aromatic hydrocarbons and aromatic azo derivatives. PMID- 4164143 TI - A naturally occurring fragment related to the heavy chains of immunoglobulin G in normal human urine. PMID- 4164144 TI - F'c fragment of immunoglobulins. PMID- 4164145 TI - Use of charged thiol reagents in interpreting the electrophoretic patterns of immune globulin chains and fragments. PMID- 4164146 TI - Transplantation immunity: localization in mouse serum of antibodies responsible for haemagglutination, cytotoxicity and enhancement. PMID- 4164147 TI - Lack of natural tolerance to allotypic gamma-globulins in rabbits. PMID- 4164148 TI - Staining of Paneth cells with thioflavine T. PMID- 4164149 TI - Immunosuppressive therapy of chronic renal disease. PMID- 4164150 TI - Azure A-Schiff, alcian blue, HIO4-Schiff, Naphthol yellow S--a sequential staining method for paraffin sections. PMID- 4164151 TI - Application of methods for mammalian chromosome spreads to the cells of cestodes. PMID- 4164152 TI - Staining of small lymphoid nucleoli in paraffin sections by aniline-azure B. PMID- 4164153 TI - Staining and washing ultrathin sections; a device for handling various materials simultaneously. PMID- 4164154 TI - Simplified culture and chromosome preparations of primate leukocytes. PMID- 4164155 TI - Rapid schedules for KOH clearing and alizarin red S staining of fetal rat bone. PMID- 4164156 TI - Staining rickettsiae in sections of formalin-fixed tissue; a 12-minute Wright buffer sequence. PMID- 4164157 TI - A rapid tissue-culture stain based on Heidenhain's iron-hematoxylin but requiring no differentiation. PMID- 4164158 TI - [Recto-colonic cancer in the aged]. PMID- 4164159 TI - Management of pain in cancer, with special reference to pain caused by pelvic malignancy. PMID- 4164160 TI - [Experimental light and electron microscopic studies on Sternheimer-Malbin cells]. PMID- 4164161 TI - [Studies on the specificity of the antistreptolysin reaction]. PMID- 4164162 TI - Cytologic observations on the pancreatic islets with reference to some endocrine like cells of the gastrointestinal mucosa. PMID- 4164163 TI - Morphology of the mouse embryo, from the time of implantation to mesoderm formation. PMID- 4164164 TI - [On staining of cell border membranes of Purkinje cells of the mouse]. PMID- 4164165 TI - [On psychotropic action of a new tricyclic compound, L-methyl-amino-methyl 2,3/5,6-dibenzo-2,2,2-bicyclooctane HCl]. PMID- 4164166 TI - [Studies on an aesculetine ester]. PMID- 4164168 TI - Role of the forensic science laboratory. PMID- 4164167 TI - Natural history and clinical significance of arrhythmias after acute cardiac infarction. PMID- 4164169 TI - The relative proportions of IgG-, IgAand IgM-containing cells in rabbit tissues during experimental trichinosis. PMID- 4164170 TI - The detection of monoclonal macroglobulinemia with antisera specific for gamma-M globulins. PMID- 4164171 TI - Allotypy of serum immunoglobulins in systemic and chronic lupus erythematosus. PMID- 4164172 TI - [Studies on immunity to measles. II. Prophylactic and serological studies on the use of live and attenuated measles-virus vaccine]. PMID- 4164173 TI - Hypercalcaemia and supravalvar aortic stenosis. PMID- 4164174 TI - No questions asked. . .? PMID- 4164175 TI - Penicillin and working capacity. PMID- 4164176 TI - [Survival of skin transplants. Experimental animal study]. PMID- 4164177 TI - [Cytochemical identification of nucleic acids]. PMID- 4164178 TI - [Nerve end-organs in the skin of the badger]. PMID- 4164180 TI - [Use of "Eviprostat" on hypertrophy of the prostate]. PMID- 4164179 TI - [Evaluation of biochemical serum findings in mentally ill people]. PMID- 4164181 TI - [The distribution of polysaccharides in the interglobular areas of human dentin]. PMID- 4164182 TI - The growth of mouse bone marrow cells in vitro. PMID- 4164183 TI - The effect of anti-thyroid drugs on thyrocalcitonin secretion. PMID- 4164184 TI - Autoantibodies in ulcerative colitis. PMID- 4164185 TI - [Immunochemical study of the products of papain and pepsin proteolysis of 2 human M immunoglobulins]. PMID- 4164186 TI - Electrochromatographic separation of low molecular weight Elson-Morgan and ninhydrin-positive substances obtained by gel filtration of urine. PMID- 4164187 TI - Comparison of three methods for the estimation of the conversion factor (ratio PB 131-I: total 131-I) in biological material. PMID- 4164188 TI - Cytophysiology of the lead-hematoxylin positive cells in the hypophysis of the slender loris. PMID- 4164189 TI - Studies on the A1-cells in the endocrine pancreas of some cartilaginous fishes. PMID- 4164190 TI - Dirofilariasis in Connecticut dogs. PMID- 4164191 TI - [Histochemical and biochemical studies of the prostate (the terminal electron transport system in hypertrophy and cancer of the prostate)]. PMID- 4164192 TI - [Immunoglobulins--their classification and characteristics]. PMID- 4164193 TI - [Poly- or monoclonal hypergammaglobulinaemia]. PMID- 4164194 TI - Perinuclear halo versus koilocytotic atypia. PMID- 4164195 TI - Glycoprotein profiles of fetal and maternal serum. PMID- 4164196 TI - Anemia of pregnancy treated with single intravenous dose of iron-dextran. PMID- 4164197 TI - [LE factor and antinuclear antibodies]. PMID- 4164198 TI - [Presentation of 4 cases of ataxia telangiectasia]. PMID- 4164199 TI - Metachromatic leukodystrophy (sulfatide lipidoses) cultured in vitro. AB - Cerebral white matter from a patient with metachromatic leukodystrophly was successfully cultured in vitro. A luxuriant growth in Rose chambers and in roller tubes was apparent by the 14th day. The outgrown cells contained large numbers of granules which stained dark brown with cresyl violetacetic acid. The growth and metachromasia were maintained up to 80 days in vitro. PMID- 4164200 TI - Thyroxine interaction with actinomycin D and possible biological implications. AB - Actinomycin D and thyroxine interact in solution (pH 8 to 10), as revealed by changes in the absorbance of actinomycin D. Thyroxine can prevent the growth inhibitory effect of actinomycin D on Bacillus subtilis if it is present in a molar ratio of 3000 (thyroxine to actinomycin D). PMID- 4164201 TI - Toxicity of antibiotics in laboratory rodents. PMID- 4164202 TI - On the metabolites of penicillium duclauxi delacroix--3. The reactions of duclauxin with ammonia and primary amines. The structures of desacetylduclauxin, neoclauxin, xenoclauxin and cryptoclauxin. PMID- 4164203 TI - Biosynthesis of duclauxin. PMID- 4164204 TI - Experimental studies on the pathogenesis of leucodystrophies. II. The effect of sphingolipids on various cell types in cultures from the nervous system. PMID- 4164205 TI - Lead encephalo-myelopathy of the suckling rat and its implications on the porphyrinopathic nervous diseases. With special reference to the permeability disorders of the nervous system's capillaries. PMID- 4164206 TI - Congenital metachromatic leukodystrophy. Report of a case. PMID- 4164207 TI - [Sequential treatment in menstrual irregularities and ovulation disorders]. PMID- 4164208 TI - [Use of a synthetic estro-progestational hormone: C. S. 1516 in gynecologic therapeutics. Apropos of 39 cases]. PMID- 4164209 TI - Separation of two trypsin-binding alpha-2-globulins of human serum. PMID- 4164210 TI - [Measurement of the trypsin inhibition capacity of human serum]. PMID- 4164211 TI - Electrophoresis and immunoelectrophoresis of pericardiac fluid proteins. PMID- 4164212 TI - Histopathology of the larger colonic polyp. PMID- 4164213 TI - Massive hemorrhage from colonic diverticula caused by arterial erosion: a practical theory of its mechanism and causation: report of two cases. PMID- 4164214 TI - Affinity of animal cell nucleoli for normal serum. Preliminary characterization of serum and cell components. AB - Nucleoli of animal cells cultured in vitro are modified by a component of "nonimmune" animal serum. Modified nucleoli bind fluorescein-conjugated nonimmune serum proteins, as shown by calcium ion-dependent fluorescence. Analysis of serum indicates that the nucleolar-binding component is a globulin, with an electrophoretic mobility in the same region as the slow alpha-1 component in pH 8.6 Veronal buffer. The component has a low sedimentation constant (2.4S), and appears to contain glycoprotein with relatively high sialic acid content (8.5%); the latter moiety may be essential to reaction with nucleoli. The nucleolar component reacting with this alpha globulin fraction appears to be a histonelike basic protein. Primary cultures of animal cells have been supported for 1 wk through attachment, spreading, and outgrowth from colonies to confluent monolayers in medium containing a nucleolar-reactive serum fraction as the only protein supplement. PMID- 4164215 TI - Phosphotungstic acid-hematoxylin, reactivity in vitro. PMID- 4164216 TI - Microspectrophotometric analysis of basic protein rich sites stained with Biebrich scarlet. PMID- 4164217 TI - Nephrotoxic serum nephritis in complement intact and deficient mice. PMID- 4164218 TI - [Adenoma of the prostate]. PMID- 4164219 TI - [Medical progress and the physician's responsibilities]. PMID- 4164220 TI - [Cardiac catheterization. 2]. PMID- 4164221 TI - [Principles of respiratory reanimation. 1. Respiratory insufficiency; principles and methods of treatment]. PMID- 4164222 TI - [The immediate and long-term problems posed by total cystectomy. 1. The intervention]. PMID- 4164224 TI - [Man against the rat]. PMID- 4164223 TI - [The under-6-year-old child in front of television]. PMID- 4164225 TI - [Preventive technics and technics of prevention]. PMID- 4164226 TI - [Genetics]. PMID- 4164227 TI - [Chelating agents]. PMID- 4164228 TI - [Palace or hovel, can the hospital be sanitary?]. PMID- 4164229 TI - [The immediate and long-term problems posed by total cystectomy. 2. The surgical results]. PMID- 4164230 TI - [Laparoscopy]. PMID- 4164231 TI - [The treatment of whooping cough]. PMID- 4164232 TI - [The pediatric nurse and the psychological problems posed by the hospitalized leukemia child and by his family. 1]. PMID- 4164233 TI - [Birth control. Report of the Chief Advisory Committee on Population and Family]. PMID- 4164234 TI - [The application of operational research in health planning]. PMID- 4164235 TI - [An evaluation of the needs of personnel recruitment in health and social services in France]. PMID- 4164236 TI - [Conference on the marginal states between life and death]. PMID- 4164237 TI - [Admission to schools of masso-kinesitherapy]. PMID- 4164238 TI - How effective is TV as a bedside teaching aid? PMID- 4164239 TI - The hibernation cycle and related changes in the brown fat tissue of Citellus lateralis. PMID- 4164240 TI - Electron microscopic observations on the substructure of tobacco rattle virus. PMID- 4164241 TI - Molecular nature of the drug-resistance factors of the Enterobacteriaceae. PMID- 4164242 TI - Note on the theory of symbolic transformations. PMID- 4164243 TI - Rapid staining procedures for differentiating plant virus inclusions in epidermal strips. PMID- 4164244 TI - Discrete gammaglobulin (M-)components in serum. Clinical study of 150 subjects without myelomatosis. PMID- 4164245 TI - Reversible inactivation of an endotoxin by plasma proteins. PMID- 4164246 TI - The inactivation of endotoxin after interaction with certain proteins of normal serum. PMID- 4164247 TI - The histamine-sensitizing effect of endotoxins. PMID- 4164248 TI - Role of antibodies in reactions to gram-negative bacterial endotoxins. PMID- 4164249 TI - Protection against lethality of E. coli endotoxin with "O" antiserum. PMID- 4164250 TI - Uric acid excretion following pelvic perfusion for malignancy. PMID- 4164251 TI - Radioactive iodine, antithyroid drugs, and surgery in treatment of hyperthyroidism. PMID- 4164252 TI - Fractionation on DEAE-Sephadeex of normal and a-myeloma human sera. I. Electrophoretic heterogeneity of gamma-a globulins. PMID- 4164253 TI - Regulation of the initiation of hemoglobin synthesis in the blood island cells of chick embryos. 3. Qualitative studies of the effects of 8-azaguanine and preparations of transfer RNAs. PMID- 4164254 TI - Dicumarol: a novel inhibitor of steroid 11-beta-hydroxylation. PMID- 4164255 TI - Determination of chlorinated insecticides in human blood. PMID- 4164256 TI - Lupoid features in a case of leprosy. PMID- 4164257 TI - The morphologic and physiologic basis for a new classification of lymphoedema. PMID- 4164258 TI - Evidence for in vivo breakdown of beta-10-globulin in hypocomplementemic glomerulonephritis. AB - Evidence has been obtained for the presence in vivo of alpha(2D)-globulin, a breakdown product of serum beta(1C)-globulin, in patients with acute and persistent hypocomplementemic glomerulonephritis. The protein has been identified by immunoelectrophoretic analysis, and the amounts present have been determined by direct measurement of specific antigenic determinants present on alpha(2D). beta(1A)-Globulin, another breakdown product of beta(1C)-globulin, may also be present in vivo in severely hypocomplementemic patients, but its levels are much lower than those of alpha(2D)-globulin.Alpha(2D)-globulin has been identified by immunoelectrophoretic analysis of fresh EDTA plasma from patients with hypocomplementemic nephritis as an arc in the alpha(2) region that shows a reaction of identity with the arc representing alpha(2D)-globulin produced by aged normal serum. beta(1A)-Globulin was not seen in these patterns. Measurement of specific antigenic determinants has been carried out in both fresh EDTA plasma and aged serum. In the fresh plasma, the concentration of D antigen, found on both beta(1C)- and alpha(2D)-globulins, has been related to that of B antigen, found only on beta(1C) and taken as a measure of the concentration of this protein. In the hypocomplementemic patients, the concentration of D antigen, in comparison to that of B, was greater than in the normal subjects. Similarly, in aged serum, the level of alpha(2D) was greater than would be expected from the amount of beta(1C) that had been broken down in vitro, measured by the concentration of beta(1A). Calculations indicated that the in vivo alpha(2D) level in severely hypocomplementemic patients ranged from 7.5 to 18% of that which would be found in a pool of aged normal serum in which beta(1C) is completely broken down. The levels tended to be lower in less severely hypocomplementemic patients, and none could be detected in normal plasma. Only small quantities of A and D antigens are detectable in the urine of patients with hypocomplementemic nephritis. The rate of excretion is about equal to that of the normal subject. The study indicates that the low serum levels of beta(1C) globulin that may be present over long periods in patients with persistent hypocomplementemic glomerulonephritis can be ascribed, in part, to in vivo breakdown of this protein as a result of reaction with immune complexes. The contribution of beta(1C) deposition on immune complexes and of diminished synthesis to the depressed serum levels cannot be assessed by the present study. PMID- 4164259 TI - Immunopathologic studies of systemic lupus erythematosus (SLE). I. Tissue-bound immunoglobulins in relation to serum antinuclear immunoglobulins in systemic lupus and in chronic liver disease with LE cell factor. AB - We studied the composition of tissue-bound immunoglobulins and of antinuclear factors by immunofluorescent techniques in five patients with systemic lupus and two with chronic liver disease associated with positive LE cell tests. Renal glomeruli in all seven demonstrated deposits of bound gammaG-globulin and complement, although the presence of gammaA- and gammaM-immunoglobulins was variable. Blood vessel walls contained primarily gammaG-globulin and complement in the systemic lupus patients, but such deposits were absent from vessels in the two with chronic liver disease. We observed antinuclear factors, demonstrated by immunofluorescence, in all three immunoglobulin classes. In six of the seven patients, evidence was obtained of a correspondence between the classes of bound immunoglobulins in glomeruli and vessels and the serum titers of antinuclear immunoglobulins. These observations are consistent with the concept that immunoglobulin deposits in tissues may be derived at least in part from antinuclear factors. Neither bound immunoglobulins nor complement was observed in liver parenchyma of the two patients with chronic liver disease or in two patients with systemic lupus and liver pathology. It thus seems doubtful that serum antibodies play a primary role in the pathogenesis of forms of chronic liver disease associated with positive LE cell tests. PMID- 4164260 TI - Immunopathologic studies of systemic lupus erythematosus. II. Antinuclear reaction of gamma-globulin eluted from homogenates and isolated glomeruli of kidneys from patients with lupus nephritis. AB - The gammaG-globulin eluted at acid pH from kidney cortex homogenates and isolated glomeruli of five of six patients with lupus nephritis was found to exhibit antinuclear activity, which was not dependent on presence of fresh human serum. Specificity, as demonstrated by absorption of antinuclear activity, was related to nucleoprotein in three glomerular acid eluates and to DNA in two acid eluates as well as in a deoxyribonuclease digest of disrupted glomeruli in one patient. Antinuclear activity was not found in acid eluates of kidneys from two patients with chronic liver disease and chronic discoid lupus, respectively, and one with lupus nephritis. These patients had a low titer of serum antinuclear factor and lesser amounts of kidney bound immunoglobulins. The presence of antinuclear activity in eluates of kidneys appeared to correlate with the amount of glomerular bound immunoglobulin and the level of antinuclear antibodies in serum. These findings suggest that in lupus nephritis, part of the glomerular bound immunoglobulin is derived from serum antinuclear factors possibly deposited as immune complexes. PMID- 4164262 TI - Districts, Pennsylvania Dental Association. PMID- 4164263 TI - Stainless steel crowns. PMID- 4164261 TI - [Antigen-antibody reactions in the gastric mucosa. Passive mucosal anaphylaxis and application of soluble antigen-antibody complex for the mucosa]. PMID- 4164265 TI - Advantages of mixed dentition treatment. PMID- 4164264 TI - The handicapped dental patient. PMID- 4164266 TI - Vital staining of Histoplasma capsulatum with Janus Green B. PMID- 4164267 TI - [Apropos of a sporadic case of distal myopathy]. PMID- 4164268 TI - [The effect of continuous pressure breathing on the protein level of rabbits]. PMID- 4164269 TI - Experimental arteriosclerosis in dogs: the effects of triton-induced hyperlipemia. PMID- 4164270 TI - Phenobarbitone and the shoulder-hand syndrome. PMID- 4164271 TI - Electrophoretic studies of sera from cattle vaccinated or naturally infected with Brucella abortus. AB - Examinations of the electrophoretic behaviour in cellulose acetate were made on the proteins of sera from 18 field cases of brucellosis, 15 calves recently vaccinated with strain 19 Brucella abortus and from 28 normal cattle. The total protein and gamma-globulin content of the sera of the naturally infected, serologically positive cattle tended to be somewhat higher than that of sera from most normal cattle. A few of the serologically-negative normals also had defenitely elevated serum gamma-globulin values. In the vaccinated calves there was an increase both in total serum protein and gamma-globulin but its magnitude in different individuals was not directly related to the rise in their antibody titre. PMID- 4164272 TI - Protein-bound iodine determination by activation analysis. PMID- 4164273 TI - A mumps epidemic on St. George Island, Alaska. PMID- 4164274 TI - [Serological study on antinuclear factors with special reference to its heterogeneity]. PMID- 4164276 TI - [On use of streptomycin and dihydrostreptomycin]. PMID- 4164275 TI - The physiological role of the lymphoid system. I. An extension of the mechanism of antibody-antigen reaction. PMID- 4164277 TI - Preparation of permanent whole mounts of marine centric diatoms to permit observations of cytoplasmic inclusions. PMID- 4164278 TI - Infiltrating and embedding tissues with mixtures of polyethylene glycols and polyvinylacetate resins. PMID- 4164279 TI - Bird erythrocytes in experimentally introduced blood clots, for differentiation from autogenous mammalian clots. PMID- 4164280 TI - A microspectrophotometric analysis of staining with carmine, orcein and carmine orcein. PMID- 4164281 TI - Polychromasia of cresyl violet dyes; a chemical explanation of variations in pre World War II products. PMID- 4164282 TI - Histochemical analysis of microdissected nephrons: enzyme stains. PMID- 4164283 TI - Controlled-heat fixation of smears and thin tissue slices in liquid mercury. PMID- 4164284 TI - A basic fuchsin-alcian blue stain for the human hypophysis. PMID- 4164285 TI - A general stain based on Gallego's method for connective tissue. PMID- 4164286 TI - [Various antithyroid substances]. PMID- 4164287 TI - Lipid-protein interrelationship in pregnancy. PMID- 4164288 TI - The histochemical localization of calcium in the keratohyalin granules of human oral epithelium. PMID- 4164289 TI - Iodine metabolism in young chinook salmon (Oncorhynchus tschawytscha, Walbaum). I. Thyroidal impairment with the use of 131-I. PMID- 4164290 TI - Effect of EDTA on histochemical demonstration of phosphorylase activity. PMID- 4164291 TI - Electron microscope studies of antigen-antibody complexes. PMID- 4164292 TI - Reticulocytosis in renal failure. PMID- 4164293 TI - Segmental infarcts of the small intestine and mesenteric adenitis in Thai children. PMID- 4164294 TI - Glucose tolerance, age, and circulating insulin. PMID- 4164295 TI - Maternal serum-proteins in idiopathic respiratory distress syndrome of the newborn. PMID- 4164296 TI - Trophoneurotic blisters in elderly hemiplegics. PMID- 4164297 TI - Diagnosis of posterior urethral inflammation in the male. PMID- 4164298 TI - Absence of harmful effect of maternal hypocapnia in babies delivered at caesarean section. PMID- 4164299 TI - Hydrocortisone-production rates in Africans. PMID- 4164300 TI - Venous distension in strangulated femoral hernia. PMID- 4164301 TI - Measurement of glomerular filtration-rate in man using a 51Cr-edetic-acid complex. PMID- 4164302 TI - Enhancement by caffeine of glucagon-induced and tolbutamide-induced insulin release from isolated foetal pancreatic tissue. PMID- 4164303 TI - Cells in human spleen forming antibody to sheep erythrocytes. PMID- 4164304 TI - A transmission model for kuru. PMID- 4164305 TI - Oral contraceptives and thromboembolism. PMID- 4164306 TI - The advance of cholera. PMID- 4164307 TI - Antibody, antimind? PMID- 4164308 TI - An ABC of modern immunology. I. Links between the old and the new. PMID- 4164309 TI - Viral hepatitis. A staff hazard in dialysis units. PMID- 4164310 TI - Pneumococcus resistant to erythromycin and lincomycin. PMID- 4164311 TI - Fatal granulomatous disease of childhood. PMID- 4164312 TI - Efficient use of blood. PMID- 4164314 TI - Chromosome anomalies. PMID- 4164313 TI - Octanoic acid and free fatty acids. PMID- 4164315 TI - Frusemide in acute pulmonary oedema. PMID- 4164316 TI - Adult coeliac disease and neuropathy. PMID- 4164317 TI - Sickle-cell anaemia in G.-6-P.D. deficiency. PMID- 4164318 TI - Merokinetic effect of Anovlar. PMID- 4164319 TI - Thyroxine and hypolipidaemic effect of clofibrate. PMID- 4164320 TI - Efect of "Dicumarol" (bishydroxycoumarin) on insulin secretion in vitro. PMID- 4164321 TI - Modified vesicourethroplasty for the contracted vesical neck. Technic and clinical results. PMID- 4164322 TI - [So-called primary acquired hypogammaglobulinemia]. PMID- 4164323 TI - On the origin of lactic dehydrogenase isoenzymes in urine. PMID- 4164324 TI - Specificity of the antiglobulin test in "auto-immune" hemolytic anemias. PMID- 4164325 TI - Application of an in vitro cariogenic technic to study the development of carious lesions around dental restorations. PMID- 4164326 TI - Fluoride levels of plasma and cerebrospinal fluid. PMID- 4164327 TI - In vitro absorption of gamma-globulin by neonatal intestinal epithelium of the pig. AB - 1. An in vitro method, using fluorescent gamma-globulin and everted neonatal pig's intestinal slices, for the study of the active transport of large molecules is described.2. Uptake of gamma-globulin occurred within 15 min and required no exogenous substrates.3. In vitro absorption of gamma-globulin by intestinal epithelium was limited to the neonatal pig and 5-day-old mouse. No uptake was seen in intestines from a mature mouse, a pig with diarrhoea, a normal pig, a mature rabbit, a guinea-pig, a chick, and a chick embryo. Chick embryo yolk sac readily took up gamma-globulin.4. Rings of everted intestinal epithelium remained active (still absorbed gamma-globulin) after incubating for 4-6 hr in balanced salt solution (BSS).5. Uptake of gamma-globulin required oxygen and sodium and was reversibly inhibited by metabolic antagonists such as iodoacetate, arsenate, fluoride, 4,6-dinitro-varphi-cresol, phlorrhizin, anaerobiosis and cold. Under the conditions of the test, large colloidal molecules did not inhibit uptake of gamma-globulin.6. Similar results (although not as clear-cut) with metabolic inhibitors were obtained with preparations of chick embryo yolk sacs.7. Injuring mature pig's intestinal epithelium with surface-active agents did not produce non specific absorption artifacts that resembled the specific absorption found in immature pig's intestinal epithelium. PMID- 4164328 TI - A possible genetic basis for specific pattern in antibody. PMID- 4164329 TI - Structural heterogeneity of L chains in antibodies of restricted specificity. PMID- 4164330 TI - Medical services under TITLE XIX. PMID- 4164331 TI - Flaps and flap necrosis. Improving the circulation in skin flaps with Complamin and with Dicoumarol: animal experiments. PMID- 4164332 TI - [Therapy of skin diseases with Hameran cream]. PMID- 4164333 TI - Hyperplasia, atypism, and carcinoma in situ in prostatic periurethral glands. PMID- 4164334 TI - Variations in argentaffin cells in experimental gastritis. PMID- 4164335 TI - Bifunctional imidoesters as cross-linking reagents. PMID- 4164336 TI - Reversal of azide inhibition by uncouplers. PMID- 4164337 TI - Antinuclear antibodies and nuclear antigens. AB - The lupus erythematosus (LE) cell factor is one of a variety of heterogeneous antibodies directed against many nuclear antigens. These antinuclear antibodies are found in a wide variety of clinical disorders. As detected by immunofluorescence techniques, they are so frequently found in association with systemic lupus erythematosus that their absence essentially excludes that diagnosis. It is suggested that in certain situations other than systemic lupus, antinuclear antibodies may be the result of some inflammatory and destructive processes. Antinuclear antibodies may be detected in certain lower animals frequently in association with disease. In lower animals, immunization with nuclear antigens appropriately complexed* to protein carriers consistently results in the induction of antinuclear antibodies. In both man and animals, antinuclear antibodies are often detected without associated disease. Furthermore, antinuclear antibodies are not injurious to intact tissue culture cells. Nonetheless, antigen-antibody complexes consisting of nuclear antigens and antinuclear antibodies may contribute to the propagation of certain diseases, particularly lupus nephritis. The use of antinuclear antibodies as immunochemical tools holds great promise for the better understanding of such nuclear antigens as are found in viruses and in the nuclei of certain malignant cells. PMID- 4164339 TI - [Abnormal gamma globulin--a study on plasmacytoma]. PMID- 4164338 TI - Effect of progestational agents on gonadal and adrenal cortical function in patients with benign prostatic hypertrophy and carcinoma of the prostate. PMID- 4164340 TI - [Immunochemical evaluation for the treatment of chronic thyroiditis]. PMID- 4164341 TI - [Determination of triiothyronine binding to serum proteins by means of dextran gel filtration]. PMID- 4164342 TI - [Comparative studies of endocrine glands and enzyme activities in dystrophia myotonica and myotonia congenita]. PMID- 4164344 TI - [Massive oral calcium therapy in the treatment of osteoporosis]. PMID- 4164343 TI - [The optical rotatory dispersion of electrophoretically isolated paraproteins. I. On group specificity of normal and pathologic gamma globulins]. PMID- 4164346 TI - Nucleolar architecture in root meristematic cells of Allium cepa. PMID- 4164345 TI - Morphological observations on the nucleolus of cells in tissue culture, with special regard to its composition. PMID- 4164347 TI - Nucleolar-chromosomal interaction in microspores of maize. PMID- 4164348 TI - Synthesis of transfer RNA in the nucleolus of Smittia. PMID- 4164349 TI - Autoradiographic, biochemiical, and ultrastructural studies into the effect of actinomycin, 5-fluorouracil, and adenosine on nucleolar and cellular structure and function. PMID- 4164350 TI - RNA metabolism in the HeLa cell nucleus and nucleolus. PMID- 4164351 TI - The nucleolus and ribosomal RNA synthesis in mammalian cells. PMID- 4164352 TI - [Research on the nature of the substrates of endogenous respiration of Yoshida's ascites hepatoma]. PMID- 4164353 TI - Histologic studies of human coronal dentine following cavity preparations and exposure of ground facets in vivo. PMID- 4164354 TI - Homogenous deposits in the membranous semicircular canals. PMID- 4164355 TI - The effect of phytohaemagglutinin on the metabolism and gamma-globulin synthesis of human lymphocytes. PMID- 4164356 TI - Antibody purification on insoluble adsorbents and purification and characterization of immunoglobulin A. AB - A meeting, sponsored by WHO, was held at the WHO International Reference Centre for Immunoglobulins in Lausanne, Switzerland, from 12 to 17 March 1966 to review (a) antibody purification on insoluble adsorbents and (b) immunoglobulin A (IgA, gammaA) purification and characterization.The text below-prepared by Dr J. L. Fahey, Dr E. C. Franklin, Dr R. S. Nezlin and Dr T. Webb-is a precis of some of the statements made at this meeting.(a) PMID- 4164357 TI - [On the behavior of protein-bound iodine (PB-127J) in the serum following administration of iodine containing substances, especially x-ray contrast media]. PMID- 4164358 TI - [Differential diagnostic difficulties in multiple sclerosis]. PMID- 4164359 TI - Effect of menadione on the phagocytic activity of guinea-pig polymorphonuclear leucocytes. PMID- 4164360 TI - Effect of experimental allergic encephalomyelitis gamma-globulin upon the electrical activity of the brain. PMID- 4164362 TI - Comment on Dr Ritvo's paper. PMID- 4164361 TI - Purification of ferritin-labelled immunoglobulins. PMID- 4164363 TI - The adaptive use of regression. PMID- 4164364 TI - Pathogenesis of the renal lesion associated with the abuse of analgesics. PMID- 4164365 TI - Maternal and foetal ketone concentrations in plasma and urine. PMID- 4164366 TI - Probable gallbladder infection in convalescent cholera patients. PMID- 4164367 TI - Influence of hyperbaric oxygen on the survival of split skin grafts. PMID- 4164368 TI - The iliofemoral venous segment as a source of pulmonary emboli. PMID- 4164369 TI - Hydrocephalus due to elongated basilar artery. A new clinicoradiological syndrome. PMID- 4164370 TI - Cerebral blood flow in subarachnoid hemorrhage. PMID- 4164371 TI - Tyrosine metabolism and faecal aminoacids in cystic fibrosis of the pancreas. PMID- 4164372 TI - The possibility of predicting the efficacy of cancer chemotherapy in the prolongation of survival. PMID- 4164374 TI - Design of operating-theatres. PMID- 4164373 TI - Simple warning system for apnoea in premature infants. PMID- 4164375 TI - Myocarditis. PMID- 4164376 TI - Polymyositis. PMID- 4164377 TI - Breast cancer. PMID- 4164378 TI - Tetanus in Britain. PMID- 4164380 TI - Student health in Oxford. PMID- 4164379 TI - Iliofemoral thrombosis. PMID- 4164381 TI - Renal stones and sodium. PMID- 4164383 TI - Planning for community health. PMID- 4164382 TI - II. Antibodies anatomised. PMID- 4164384 TI - Efficient use of blood. PMID- 4164385 TI - Guillain-Barre syndrome complicating mumps. PMID- 4164386 TI - Neurotoxic side-effects of piperazine. PMID- 4164387 TI - Jaundice from potassium p-aminobenzoate. PMID- 4164388 TI - Fibroblast chromosome preparations. PMID- 4164389 TI - Systematic desensitisation for phobias. PMID- 4164390 TI - Classifying protein-calorie malnutrition. PMID- 4164391 TI - Oral contraceptives and thromboembolism. PMID- 4164392 TI - Skin reactions to phytohaemagglutinin. PMID- 4164393 TI - Acetylcysteine in airway maintenance. PMID- 4164394 TI - Hypersensitisation by measles virus. PMID- 4164395 TI - Pregnancy tests and proteinuria. PMID- 4164396 TI - Systemic effects of skin disease. PMID- 4164397 TI - Pontine gliomas of childhood. PMID- 4164398 TI - Clinical and pathological significance of asymptomatic atrophic thyroiditis. A condition of latent hypothyroidism. PMID- 4164399 TI - Renal haemodialysis in porphyria. PMID- 4164400 TI - Iodide goitre. PMID- 4164401 TI - Change in gastric iron-binding protein (gastroferrin) during iron-deficiency anaemia. PMID- 4164403 TI - Heterograft aortic-valve replacement. PMID- 4164402 TI - Phenylalanine-hydroxylase activity in hyperphenylalaninaemia. PMID- 4164404 TI - Radiocalcium turnover in man. PMID- 4164405 TI - Design of outpatient departments. PMID- 4164406 TI - The grey bar. PMID- 4164407 TI - The nature of pain. PMID- 4164408 TI - Iodide goitre. PMID- 4164409 TI - Propranolol. PMID- 4164410 TI - Wound repair: sutures or strips? PMID- 4164411 TI - A telluric disease. PMID- 4164412 TI - 3. Immunoglobulin physiology. PMID- 4164413 TI - Community medicine. PMID- 4164414 TI - Heat as the cause of dental decay. PMID- 4164415 TI - Propranolol. PMID- 4164416 TI - [Study of the activity of a sulfomucopolysaccharide extractive on the blood-lipid and fibrinolytic pattern in atherosclerotic disease]. PMID- 4164417 TI - Heterogeneity of heavy (gamma) chain preparations from human gamma G immunoglobulins. PMID- 4164418 TI - Foreign body reaction of the brain. Enzyme-histochemical study in dogs. PMID- 4164419 TI - Keratomycosis: an ultrastructural study. PMID- 4164420 TI - Fluorescent probes for conformational states of proteins. I. Mechanism of fluorescence of 2-p-toluidinylnaphthalene-6-sulfonate, a hydrophobic probe. PMID- 4164421 TI - Ruby laser micro-irradiation of single tissue culture cells vitally stained with Janus green B. I. Effects observed with the phase-contrast microscope. PMID- 4164422 TI - Effect of papain digested, univalent antibody on the morphology, cleavage and fertilizing capacity of sea urchin eggs. PMID- 4164423 TI - Congenital rubella syndrome in late infancy. PMID- 4164424 TI - A comparison of neutralizing antibodies to rubella virus in gamma globulin and "convalescent" sera. PMID- 4164426 TI - Experimental studies on the pathogenesis of leucodystrophies. I. The effect of intracerebrally injected sphingolipids in the rat's brain. PMID- 4164427 TI - Failure to detect 3,4-dimethoxyphenylethylamine in the urine of psychotic children. PMID- 4164428 TI - Plasma growth hormone after arginine infusion. Clinical experiences. PMID- 4164429 TI - Characterization of the antibody response to acetone-killed typhoid vaccine. PMID- 4164430 TI - [Principles of respiratory reanimation. 2. Assisted respiration--oxygen therapy- methods of resuscitation]. PMID- 4164431 TI - Some effects of clofibrate in hypothyroidism and on the metabolism of thyroxine. PMID- 4164432 TI - A filter method for processing small samples of marine ova through fixation, dehydration, and embedding without changing containers. PMID- 4164433 TI - [Telephone call: nursing 1966]. PMID- 4164434 TI - [Educational material from Kodak]. PMID- 4164435 TI - Fact sheet on dental prepayment. PMID- 4164436 TI - Establishing occlusal vertical dimension in edentulous patients. PMID- 4164437 TI - Dental care for homebound patients in Philadelphia. PMID- 4164438 TI - [Repeated hemodialysis in chronic renal insufficiency]. PMID- 4164439 TI - [Surveillance of comas]. PMID- 4164440 TI - [Female sterility]. PMID- 4164441 TI - [The surveillance and future of a patient following a stomach operation]. PMID- 4164442 TI - [The pediatric nurse and the psychological problems posed by the hospitalized leukemia child and by his family. 2]. PMID- 4164443 TI - [A survey of the professional life of the Japanese nurse]. PMID- 4164444 TI - [The need for an international standardization of measures relative to drugs which can only be given out on prescription]. PMID- 4164445 TI - [The installation of an electronic monitor in cardiology]. PMID- 4164446 TI - Chromosomal aberrations common to three types of monoclonal gammopathies. PMID- 4164447 TI - Treatment by prostatic injection of acute urinary retention due to prostatic hyperplasia. PMID- 4164448 TI - Thyroid hormone secretion by the fetal thyroid gland. PMID- 4164449 TI - The localization and distribution of protein-bound sulfhydryl and sisulfide groups in skeletal tissues of mice during growth and aging. PMID- 4164450 TI - Isolation and characterization of Lafora bodies in two cases of myoclonus epilepsy. PMID- 4164451 TI - A chemical basis for the staining of myelin sheaths by luxol dye techniques; further observations. PMID- 4164452 TI - Transformation of astrocytes and destruction of spongioblasts induced by a simian tumor virus (SV40) in cultures of human fetal neuroglia. PMID- 4164453 TI - Immunohistochemical studies in diabetic glomerulosclerosis. PMID- 4164454 TI - The phases of muscle necrosis. PMID- 4164455 TI - Thymic dysplasia ("Swiss agammaglobulinemia"). I. Graft versus host reaction following bone-marrow transfusion. PMID- 4164456 TI - Immunoglobulins and other proteins in commercial preparations of gamma globulin. PMID- 4164457 TI - Actinomycin D in management of Wilms' tumor. PMID- 4164458 TI - Distribution in human nasopharyngeal tonsils of plasma cells containing different types of immunoglobulin polypeptide chains. PMID- 4164460 TI - A light and electron microscopic study of the effects of a single dose of cyclophosphamide on various organs in the rat. I. The urinary bladder. PMID- 4164459 TI - Human renal ultrastructure. II. The thin limb of Henle's loop and the interstitium in healthy individuals. PMID- 4164461 TI - Bile ductules in cholestasis: morphologic evidence for secretion and absorption in man. PMID- 4164462 TI - Intravenous glucose-tolerance test in parents of diabetic children. PMID- 4164463 TI - Influence of pregnancy and oral contraception on the incidence of strokes in women of childbearing age. PMID- 4164464 TI - Vasomotor-relfex response in idiopathic and hormone-dependent migraine. PMID- 4164465 TI - Influence of environmental factors on foetal growth in man. PMID- 4164466 TI - The effect of retinol (vitamin-A alcohol) on urinary excretion of mucopolysaccharides in the Hurler syndrome. PMID- 4164467 TI - Iron distribution in the liver of patients with thalassaemia major. PMID- 4164468 TI - Relief of pain in labour. PMID- 4164469 TI - Cerebral-cortex-perfusion rates in migraine. PMID- 4164470 TI - Accidental hypothermia treated by extracorporeal blood warming. PMID- 4164471 TI - Automatic equilibration of volume in exchange transfusion in adults. PMID- 4164473 TI - Autoimmunity in idiopathic addison's disease. PMID- 4164472 TI - Oral contraceptives and thromboembolism. PMID- 4164474 TI - Alcohol shift. PMID- 4164475 TI - Coagulation--fibrinolysis. PMID- 4164476 TI - Paddy-field foot. PMID- 4164477 TI - Is the anesthetic really necessary? PMID- 4164478 TI - Mycoplasmas. PMID- 4164479 TI - Some practical aspects of intensive cytotoxic therapy. PMID- 4164480 TI - An ABC of modern immunology. V. The immunological capability of small lymphocytes. PMID- 4164481 TI - Kissing as a mode of transmission of infectious mononucleosis. PMID- 4164482 TI - Incorporation of labeled amino acids into serum and tissue proteins from normal and x-irradiated mice. PMID- 4164483 TI - 131-I-tobacco mosaic virus inhibition of hemolysin formation in rabbits. PMID- 4164484 TI - Molecular weight of renin determined by Sephadex G-200 gelfiltration. PMID- 4164485 TI - A general program for maximum likelihood estimation of gene frequencies. PMID- 4164486 TI - Granular dystrophy of the cornea. A histochemical and electron microscopic study. PMID- 4164487 TI - Quantitative immunoglobulin levels (IgG, IgA and IgM) in children with intractable asthma.